CA2585995A1 - Multimaterial diaphragm - Google Patents

Multimaterial diaphragm Download PDF

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Publication number
CA2585995A1
CA2585995A1 CA002585995A CA2585995A CA2585995A1 CA 2585995 A1 CA2585995 A1 CA 2585995A1 CA 002585995 A CA002585995 A CA 002585995A CA 2585995 A CA2585995 A CA 2585995A CA 2585995 A1 CA2585995 A1 CA 2585995A1
Authority
CA
Canada
Prior art keywords
disk
diaphragm
diaphragm according
central axis
bonded
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002585995A
Other languages
French (fr)
Other versions
CA2585995C (en
Inventor
Michael Holroyd
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norton Healthcare Ltd
Original Assignee
Norton Healthcare Ltd.
Michael Holroyd
Norton Healthcare Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norton Healthcare Ltd., Michael Holroyd, Norton Healthcare Limited filed Critical Norton Healthcare Ltd.
Publication of CA2585995A1 publication Critical patent/CA2585995A1/en
Application granted granted Critical
Publication of CA2585995C publication Critical patent/CA2585995C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0096—Hindering inhalation before activation of the dispenser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0093—Inhalators mechanically breath-triggered without arming or cocking, e.g. acting directly on the delivery valve
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor

Abstract

A metered dose inhaler for use with a pressurized aerosol container (25) which is preferably breath-actuated. A preload (460) is applied to the internal aerosol valve by an amount sufficient to result in a dose release, but this is prevented by the application of a pneumatic resisting force. The inhaler comprises a release device (520) which, upon actuation, releases the resisting force and allows the preload to actuate the aerosol valve. A metered dose of medicament is then released for inhalation by the patient. The pneumatic resisting force is established by a negative pressure region (600) defined in part by a diaphragm (440). The diaphragm (440) includes a central disk (441) of a first, relatively high stiffness material 'A' and a peripheral ring, coupled by a flexure of a second, relatively low stiffness material 'B'.

Claims (15)

1. A diaphragm comprising a relatively rigid central disk made of a first material characterized by a relatively high stiffness; a peripheral attachment ring disposed about a peripheral portion of said disk; and an annular flexure made of a second material characterized by a relatively low stiffness, and extending between said peripheral portion of said disk and said attachment ring; and wherein said annular flexure is bonded to said disk, and said disk, said annular flexure and said peripheral ring form a contiguous assembly.
2. A diaphragm according to claim 1 for defining a closed region within a medicament dispensing device including a main body, a sleeve movably positioned within said main body, and a spring operatively positioned in said main body to apply a preload force to said sleeve.
3. A diaphragm according to claim 1 wherein said relatively rigid central disk is adapted to be affixed to an inner end of said main body of said medicament dispensing device.
4. A diaphragm according to claim 1 wherein said peripheral attachment ring is adapted to be attached to a closed end of said sleeve of said medicament dispensing device.
5. A diaphragm according to claim 1 wherein said annular flexure defines a closed region between said diaphragm and said closed end of said sleeve.
6. A diaphragm according to claim 1 further comprising a valve port for providing fluid communication between said inner end of said main body and said closed region.
7. A diaphragm according to claim 1 wherein said peripheral ring is made of a second material and unitarily formed with said annular flexure.
8. A diaphragm according to claim 1 wherein said annular flexure is bonded to said disk along at least one surface substantially parallel to a central axis of said diaphragm.
9. A diaphragm according to claim 8 wherein said at least one bonding surface comprises a continuous surface axially arranged with respect to said central axis.
10. A diaphragm according to claim 1 wherein said annular flexure is bonded to said disk along at least one surface substantially traverse to a central axis of said diaphragm.
11. A diaphragm according to claim 1 further comprising a central portion made of said material and unitarily formed with and extending radially inwardly from said annular flexure, said central portion bonded to said disk along said at least one surface substantially traverse to a central axis of said diaphragm.
12. A diaphragm according to claim 11 wherein said central portion comprises a disk.
13. A diaphragm according to claim 11 wherein said central portion is also bonded to said disk along at least one surface substantially parallel to said central axis.
14. A diaphragm according to claim 13 wherein said central portion includes at least one annular wall coaxially arranged with respect to said central axis and received within an annular groove of said disk, said annular wall bonded to said disk along the at least one surface substantially parallel to said central axis.
15. A diaphragm according to claim 11 further comprising a valve port for providing fluid communication between said inner end of said main body and said closed region, and wherein said valve port passes through said central portion and said disk.
CA2585995A 2000-06-09 2001-06-08 Multimaterial diaphragm Expired - Lifetime CA2585995C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/591,321 2000-06-09
US09/591,321 US6553988B1 (en) 2000-06-09 2000-06-09 Medicament dispensing device with a multimaterial diaphragm bounding a pneumatic force chamber
CA002407279A CA2407279C (en) 2000-06-09 2001-06-08 Medicament dispensing device with a multimaterial diaphragm bounding a pneumatic force chamber

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002407279A Division CA2407279C (en) 2000-06-09 2001-06-08 Medicament dispensing device with a multimaterial diaphragm bounding a pneumatic force chamber

Publications (2)

Publication Number Publication Date
CA2585995A1 true CA2585995A1 (en) 2001-12-13
CA2585995C CA2585995C (en) 2012-08-21

Family

ID=24366021

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2585995A Expired - Lifetime CA2585995C (en) 2000-06-09 2001-06-08 Multimaterial diaphragm
CA002407279A Expired - Lifetime CA2407279C (en) 2000-06-09 2001-06-08 Medicament dispensing device with a multimaterial diaphragm bounding a pneumatic force chamber

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA002407279A Expired - Lifetime CA2407279C (en) 2000-06-09 2001-06-08 Medicament dispensing device with a multimaterial diaphragm bounding a pneumatic force chamber

Country Status (17)

Country Link
US (3) US6553988B1 (en)
EP (1) EP1289589B1 (en)
JP (2) JP2003534882A (en)
KR (1) KR100528375B1 (en)
AR (2) AR028689A1 (en)
AT (1) ATE274954T1 (en)
AU (2) AU6680601A (en)
CA (2) CA2585995C (en)
DE (1) DE60105291T2 (en)
DK (1) DK1289589T3 (en)
ES (1) ES2228890T3 (en)
GB (1) GB2366207A (en)
PE (1) PE20020185A1 (en)
PT (1) PT1289589E (en)
SI (1) SI1289589T1 (en)
TW (1) TW493997B (en)
WO (1) WO2001093933A2 (en)

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Also Published As

Publication number Publication date
AU6680601A (en) 2001-12-17
GB0114046D0 (en) 2001-08-01
US6553988B1 (en) 2003-04-29
CA2407279C (en) 2007-08-14
DE60105291T2 (en) 2005-09-15
PE20020185A1 (en) 2002-02-23
AR028689A1 (en) 2003-05-21
AU2001266806B2 (en) 2005-03-10
JP5069653B2 (en) 2012-11-07
EP1289589A2 (en) 2003-03-12
TW493997B (en) 2002-07-11
CA2585995C (en) 2012-08-21
WO2001093933A3 (en) 2002-03-14
KR100528375B1 (en) 2005-11-15
ES2228890T3 (en) 2005-04-16
EP1289589B1 (en) 2004-09-01
JP2003534882A (en) 2003-11-25
US7637260B2 (en) 2009-12-29
WO2001093933A2 (en) 2001-12-13
CA2407279A1 (en) 2001-12-13
GB2366207A (en) 2002-03-06
ATE274954T1 (en) 2004-09-15
DE60105291D1 (en) 2004-10-07
US20100065050A1 (en) 2010-03-18
AR064324A2 (en) 2009-03-25
DK1289589T3 (en) 2005-01-17
US8225780B2 (en) 2012-07-24
US20040025867A1 (en) 2004-02-12
SI1289589T1 (en) 2005-02-28
KR20030028737A (en) 2003-04-10
PT1289589E (en) 2004-12-31
JP2008296062A (en) 2008-12-11

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Effective date: 20210608