CA2573407A1 - System for performing a corneal transplantation - Google Patents

System for performing a corneal transplantation Download PDF

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Publication number
CA2573407A1
CA2573407A1 CA002573407A CA2573407A CA2573407A1 CA 2573407 A1 CA2573407 A1 CA 2573407A1 CA 002573407 A CA002573407 A CA 002573407A CA 2573407 A CA2573407 A CA 2573407A CA 2573407 A1 CA2573407 A1 CA 2573407A1
Authority
CA
Canada
Prior art keywords
cornea
donor
laser source
patient
recited
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002573407A
Other languages
French (fr)
Other versions
CA2573407C (en
Inventor
Klaus Baumeister
Tobias Kuhn
Frieder Loesel
Fritz Meisel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Technolas Perfect Vision GmbH
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Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2573407A1 publication Critical patent/CA2573407A1/en
Application granted granted Critical
Publication of CA2573407C publication Critical patent/CA2573407C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/008Methods or devices for eye surgery using laser
    • A61F9/009Auxiliary devices making contact with the eyeball and coupling in laser light, e.g. goniolenses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/008Methods or devices for eye surgery using laser
    • A61F9/00825Methods or devices for eye surgery using laser for photodisruption
    • A61F9/00831Transplantation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00969Surgical instruments, devices or methods, e.g. tourniquets used for transplantation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/008Methods or devices for eye surgery using laser
    • A61F2009/00844Feedback systems
    • A61F2009/00846Eyetracking
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/008Methods or devices for eye surgery using laser
    • A61F2009/00861Methods or devices for eye surgery using laser adapted for treatment at a particular location
    • A61F2009/00872Cornea

Abstract

A system for performing a corneal transplantation includes a laser source for generating a laser beam and a chair for positioning a patient relative to the laser source. A stabilizing element, engageable with the laser source, is fixated on the anterior surface of the patient's cornea to hold the cornea in alignment with the laser source. The laser source is then used to remove diseased tissue from the cornea of the patient, thereby creating a corneal cavity of known dimensions. In a subsequent step, a donor graft that was previously photoaltered to have substantially the same dimensions as the corneal cavity, is transplanted into the corneal cavity.

Claims (20)

1. An apparatus for performing a corneal transplantation of a donor graft from a donor cornea into a cavity in a cornea of a patient, wherein the cavity has a predetermined dimensional configuration and the apparatus comprises:
a laser source for generating a laser beam;
a means for presenting a donor cornea with an exposed anterior surface;
a stabilizing element engageable with said laser source to establish a fixed configuration therewith, said stabilizing element having a lens with a surface; and a means for selectively fixating the surface of said stabilizing element against the anterior surface of the donor cornea, to hold the donor cornea in alignment with said laser source while said laser source is activated to photoalter tissue of the donor cornea and to create the donor graft therefrom, wherein the donor graft has a substantially same dimensional configuration as the cavity for transplantation thereof into the cavity in the cornea of the patient.
2. An apparatus as recited in claim 1 further comprising:
a means for positioning the patient to selectively fixate the surface of said stabilizing element against the anterior surface of the cornea of the patient, to hold the cornea of the patient in alignment with the laser source while said laser source is activated to photoalter tissue for removal of diseased tissue from the cornea of the patient during creation of the cavity for receipt of the donor graft therein; and a means for transferring the donor graft from the donor cornea into the cavity in the cornea of the patient.
3. An apparatus as recited in claim 1 wherein the surface of said lens substantially conforms with an anterior surface of a cornea of a patient.
4. An apparatus as recited in claim 3 wherein said presenting means is a mount and said mount includes an artificial anterior chamber for fixedly holding only the donor cornea and a scleral rim of a donor eye, after the donor cornea and the scleral rim are surgically removed from the donor eye.
5. An apparatus as recited in claim 1 wherein said laser source is a femtosecond laser source.
6. An apparatus as recited in claim 1 wherein said stabilizing element is formed with a vacuum fitting, and further wherein the fixating means of the apparatus comprises:
a vacuum line connected to said vacuum fitting; and a vacuum pump in fluid communication with said vacuum line for generating a suction force to fixate the surface of said stabilizing element against the anterior surface of the donor cornea.
7. An apparatus as recited in claim 2 wherein said positioning means is a chair having a motorized control assembly for reconfiguring and moving said chair.
8. An apparatus as recited in claim 1 further comprising an alignment device mounted on said surgical laser unit for engaging with said stabilizing element, to establish the fixed configuration between said stabilizing element and said laser source.
9. A method for performing a corneal transplantation of a donor graft from the donor cornea into a cavity in a cornea of a patient, wherein the cavity has a predetermined dimensional configuration and the method comprises the steps of:
presenting a donor cornea having an exposed anterior surface;
fixating a stabilizing element against the anterior surface of the donor cornea, said stabilizing element having a lens with a surface;
engaging a laser source with said stabilizing element to align the donor cornea with said laser source; and activating said laser source to photoalter tissue of the donor cornea and to create the donor graft therefrom, wherein the donor graft has a substantially same dimensional configuration as the cavity for transplantation thereof into the cavity in the cornea of a patient.
10. A method as recited in claim 9 further comprising the steps of:
positioning the patient to selectively fixate the surface of a stabilizing element against the anterior surface of the cornea of the patient, to hold the cornea of the patient in alignment with said laser source while said laser source is activated to photoalter tissue for removal of diseased tissue from the cornea of the patient during creation of the cavity for receipt of the donor graft therein; and transferring the donor graft from the donor cornea into the cavity in the cornea of the patient.
11. A method as recited in claim 9 wherein said presenting step further comprises the steps of:
fixedly positioning the donor cornea in a mount;
attaching said mount to a platform adapter;
mounting said platform adapter on a motorized chair; and reconfiguring and moving said chair to present the donor cornea.
12. A method as recited in claim 11 wherein said positioning step further comprises the steps of:
securing the donor cornea and a scleral rim of a donor eye in an artificial anterior chamber, wherein the donor cornea and the scleral rim are surgically removed from the donor eye prior to securing the donor cornea and scleral rim in the artificial anterior chamber; and attaching said artificial anterior chamber to said mount for fixedly positioning the donor cornea in said mount.
13. A method as recited in claim 9 wherein said stabilizing element is formed with a vacuum fitting, and wherein said fixating step further comprises the steps of:
attaching a vacuum line to said vacuum fitting; and activating a vacuum pump in fluid communication with said vacuum line for generating a suction force to fixate the surface of said stabilizing element against the anterior surface of the donor cornea.
14. A method as recited in claim 9 wherein said laser source is a femtosecond laser source.
15. A system for performing a corneal transplantation which comprises:
a laser source for generating a laser beam;
a mount for holding a donor cornea in alignment with said laser source;
a means for positioning the cornea of a patient in alignment with the laser source while said laser beam is focused along a predetermined path to photoalter tissue in the cornea of the patient to create a cavity having a predetermined dimensional configuration;
a means for focusing the laser beam to a successive plurality of focal points along a substantially same predetermined path to photoalter tissue of the donor cornea and to create a donor graft therefrom having a substantially same predetermined dimensional configuration as the cavity; and a means for transferring the donor graft from the donor cornea into the cavity in the cornea of the patient.
16. A system as recited in claim 15 which further comprises:
a stabilizing element engageable with said laser source to establish a fixed configuration therewith, said stabilizing element having a lens with a surface; and a means for selectively fixating the surface of said stabilizing element against the anterior surface of the donor cornea, to hold the donor cornea in alignment with said laser source while said laser source is activated to photoalter tissue of the donor cornea.
17 17. A system as recited in claim 15 wherein said determining means comprises:
a means for measuring an x-y position of the donor cornea, according to a predefined orthogonal coordinate system, wherein the x-y plane of the coordinate system is substantially perpendicular to the beam path; and a means for measuring a z-position of the donor cornea, according to the predefined orthogonal coordinate system, wherein the z-axis of the coordinate system is substantially coincident with the beam path.
18. A system as recited in claim 17 wherein said means for measuring a z-position is a device selected from the group consisting of a Hartmann-Shack sensor and a confocal microscope.
19. A system as recited in claim 15 wherein said positioning means is a chair having a motorized control assembly for reconfiguring and moving said chair.
20. A system as recited in claim 15 wherein said laser source generates a femtosecond laser beam.
CA2573407A 2004-07-20 2005-06-27 System for performing a corneal transplantation Active CA2573407C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/895,276 2004-07-20
US10/895,276 US20060020259A1 (en) 2004-07-20 2004-07-20 System for performing a corneal transplantation
PCT/IB2005/001814 WO2006011011A1 (en) 2004-07-20 2005-06-27 System for performing a corneal transplantation

Publications (2)

Publication Number Publication Date
CA2573407A1 true CA2573407A1 (en) 2006-02-02
CA2573407C CA2573407C (en) 2010-04-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA2573407A Active CA2573407C (en) 2004-07-20 2005-06-27 System for performing a corneal transplantation

Country Status (5)

Country Link
US (1) US20060020259A1 (en)
EP (1) EP1768629A1 (en)
JP (1) JP4950045B2 (en)
CA (1) CA2573407C (en)
WO (1) WO2006011011A1 (en)

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Also Published As

Publication number Publication date
US20060020259A1 (en) 2006-01-26
JP2008506492A (en) 2008-03-06
JP4950045B2 (en) 2012-06-13
WO2006011011A1 (en) 2006-02-02
CA2573407C (en) 2010-04-20
EP1768629A1 (en) 2007-04-04

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