CA2556755C - Delta-sigma modulator for outputting analog representation of physiological signal - Google Patents
Delta-sigma modulator for outputting analog representation of physiological signal Download PDFInfo
- Publication number
- CA2556755C CA2556755C CA2556755A CA2556755A CA2556755C CA 2556755 C CA2556755 C CA 2556755C CA 2556755 A CA2556755 A CA 2556755A CA 2556755 A CA2556755 A CA 2556755A CA 2556755 C CA2556755 C CA 2556755C
- Authority
- CA
- Canada
- Prior art keywords
- signal
- physiological
- waveform
- analog
- output
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03M—CODING; DECODING; CODE CONVERSION IN GENERAL
- H03M3/00—Conversion of analogue values to or from differential modulation
- H03M3/02—Delta modulation, i.e. one-bit differential modulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03M—CODING; DECODING; CODE CONVERSION IN GENERAL
- H03M7/00—Conversion of a code where information is represented by a given sequence or number of digits to a code where the same, similar or subset of information is represented by a different sequence or number of digits
- H03M7/30—Compression; Expansion; Suppression of unnecessary data, e.g. redundancy reduction
- H03M7/3002—Conversion to or from differential modulation
- H03M7/3004—Digital delta-sigma modulation
- H03M7/3015—Structural details of digital delta-sigma modulators
- H03M7/3031—Structural details of digital delta-sigma modulators characterised by the order of the loop filter, e.g. having a first order loop filter in the feedforward path
- H03M7/3042—Structural details of digital delta-sigma modulators characterised by the order of the loop filter, e.g. having a first order loop filter in the feedforward path the modulator being of the error feedback type, i.e. having loop filter stages in the feedback path only
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03M—CODING; DECODING; CODE CONVERSION IN GENERAL
- H03M7/00—Conversion of a code where information is represented by a given sequence or number of digits to a code where the same, similar or subset of information is represented by a different sequence or number of digits
- H03M7/30—Compression; Expansion; Suppression of unnecessary data, e.g. redundancy reduction
- H03M7/3002—Conversion to or from differential modulation
- H03M7/3004—Digital delta-sigma modulation
- H03M7/3015—Structural details of digital delta-sigma modulators
- H03M7/302—Structural details of digital delta-sigma modulators characterised by the number of quantisers and their type and resolution
- H03M7/3024—Structural details of digital delta-sigma modulators characterised by the number of quantisers and their type and resolution having one quantiser only
- H03M7/3028—Structural details of digital delta-sigma modulators characterised by the number of quantisers and their type and resolution having one quantiser only the quantiser being a single bit one
Abstract
A method and apparatus for providing a substantially real-time representation of an analog representation of a physiological signal. The waveform signal from the sensor is converted into digital form. A delta-sigma modulator is used as a simple Digital-to-analog Converter (ADC). The output can then be provided through a simple hardware filter to give an analog output signal in nearly real-time, which can be used for other instruments, synchronization, display, etc.
Description
DELTA-SIGMA MODULATOR FOR OUTPUTTING ANALOG
REPRESENTATION OF PHYSIOLOGICAL SIGNAL
BACKGROUND OF THE INVENTION
[0001] The present invention relates to oximeters, and in particular to analog waveform displays in pulse oximeters.
REPRESENTATION OF PHYSIOLOGICAL SIGNAL
BACKGROUND OF THE INVENTION
[0001] The present invention relates to oximeters, and in particular to analog waveform displays in pulse oximeters.
[0002] Pulse oximetry is typically used to measure various blood chemistry characteristics including, but not limited to, the blood-oxygen saturation of hemoglobin in arterial blood, the volume of individual blood pulsations supplying the tissue, and the rate of blood pulsations corresponding to each heartbeat of a patient. Measurement of these characteristics has been accomplished by use of a non-invasive sensor which scatters light through a portion of the patient's tissue where blood perfuses the tissue, and photoelectrically senses the absorption of light in such tissue. The amount of light absorbed at various frequencies is then used to calculate the amount of blood constituent being measured.
[0003] The light scattered through the tissue is selected to be of one or more wavelengths that are absorbed by the blood in an amount representative of the amount of the blood constituent present in the blood. The amount of transmitted light scattered through the tissue will vary in accordance with the changing amount of blood constituent in the tissue and the related light absorption. For measuring blood oxygen level, such sensors have typically been provided with a light source that is adapted to generate light of at least two different wavelengths, and with photodetectors sensitive to both of those wavelengths, in accordance with known techniques for measuring blood oxygen saturation.
[0004] Known non-invasive sensors include devices that are secured to a portion of the body, such as a finger, an ear or the scalp. In animals and humans, the tissue of these body portions is perfused with blood and the tissue surface is readily accessible to the sensor.
[0005] Pulse oximeters, after processing the sensor data and calculating oxygen saturation, present that information to a display. In some pulse oximeters, it is also desirable to display the analog waveform itself. For example, US Patent No. 6,188,470 shows a signal for a display reflecting the waveform. US Patent No. 6,385,471 also discusses a waveform display, and sets forth that the data is first digitized, prefiltered, and then reconstructed for the display.
[0006] Nellcor Puritan Bennett, the assignee of the present invention, provides analog outputs in a number of its products. The analog outputs are used for such purposes as synchronizing to other instruments (e.g., EKG, multi-parameter monitor) as well as for a display. The analog waveforms are sometimes provided from the hardware pre-processing circuitry, to insure the analog signal is close in time to the actual patient waveform.
[0007] A problem with providing an analog waveform to a display after processing is that the processing takes some time, and thus the signal provided is delayed and not real-time.
BRIEF SUMMARY OF THE INVENTION
BRIEF SUMMARY OF THE INVENTION
[0008] The present invention provides a method and apparatus for providing a substantially real-time representation of an analog representation of a physiological signal.
The waveform signal from the sensor is converted into digital form. A delta-sigma modulator is used as a simple Digital-to-analog Converter (ADC). The output can then be provided through a simple hardware filter to give an analog output signal in nearly real-time, which can be used for other instruments, synchronization, display, etc.
The waveform signal from the sensor is converted into digital form. A delta-sigma modulator is used as a simple Digital-to-analog Converter (ADC). The output can then be provided through a simple hardware filter to give an analog output signal in nearly real-time, which can be used for other instruments, synchronization, display, etc.
[0009] The invention allows a waveform to be converted into digital form, and supplied to the software, while still allowing fast conversion back into hardware after initial processing in software. In particular, for a pulse oximeter that does demodulation in software, the digital IR signal can be obtained after this software demodulation, but before the much slower software filtering process used as part of the process to calculate oxygen saturation.
[0010] In one embodiment, in a first path the digital signal is processed, but a second path applies this digitized waveform to the delta-sigma modulator. The second path picks off the signal immediately after it is converted into digital form and demodulated. For a pulse oximeter, an IR signal is chosen for the analog output because it typically has less noise.
[0011] In one embodiment, the delta-sigma modulator is a software modulator which operates on the digitized version of the waveform. The delta-sigma modulator provides a single bit, serial output. This output is provided to a hardware RC filter, and then to the display.
[0011a] Accordingly, there is provided a method for operating a physiological monitor comprising: detecting an analog signal from a patient, wherein the analog signal comprises a physiological waveform; converting the analog signal into a digital signal;
demodulating the digital signal to produce at least two demodulated physiological signals;
applying one of the demodulated physiological signals to a delta-sigma modulator to provide an output signal; and filtering said output signal to provide a real-time analog filtered physiological waveform output.
[0011b] There is also provided a physiological monitor apparatus comprising:
an input for receiving from a patient an analog signal including a physiological waveform; an analog-to-digital converter for converting said analog signal into digital signal; a demodulator for demodulating the digital signal to produce at least two demodulated physiological signals; a delta-sigma modulator configured to convert one said demodulated physiological signals from digital into analog form; and a filter coupled to an output of said delta-sigma modulator.
2a ' [0012] For a further understanding of the nature and advantages of the invention, reference should be made to the following description taken in conjunction with the accompanying drawings.
BRIEF DESCRIPTION OF THE DRAWINGS
[0013] Fig. 1 is a block diagram of an oximeter incorporating the present invention.
[0014] Fig. 2 is a block diagram of a prior art circuit for generating an analog output signal.
[0015] Fig. 3 is a block diagram of an embodiment of a circuit for generating an analog output signal according to the present invention.
[0016] Fig. 4 is a block diagram of the software delta-sigma modulator according to an embodiment of the present invention.
[0017] Fig. 5 is a circuit diagram of an embodiment of the hardware RC filter according to an embodiment of the present invention.
[0018] Fig. 6 is a front view of a monitor showing an analog display according to an embodiment of the present invention.
DETAILED DESCRIPTION OF THE INVENTION
Overall System [0019] Fig. 1 illustrates an embodiment of an oximetry system incorporating the present invention. A sensor 10 includes red and infrared LEDs and a photodetector.
These are connected by a cable 12 to a board 14. LED drive current is provided by an LED
drive interface 16. The received photocurrent from the sensor is provided to an I-V
interface 18.
The IR and red voltages are then provided to a sigma-delta interface 20 incorporating the present invention. The output of sigma-delta interface 20 is provided to a microcontroller 22.
Microcontroller 22 includes flash memory for a program, and RAM memory for data. The oximeter also includes a microprocessor chip 24 connected to a flash memory 26. Finally, a clock 28 is used and an interface 30 to a digital calibration in the sensor 10 is provided. A
separate host 32 receives the processed information, as well as receiving an analog signal on a line 34 for providing an analog display.
Prior Art Demodulation in Hardware [0020] Fig. 2 shows an example of a prior art circuit for generating an analog output signal.
A signal from a patient sensor is processed in hardware through a current-to-voltage converter (I-V) 36, and a filter 37. The red and IR signals are then demodulated in a demodulator 38. A red signal is provided through a first channel of a filter 39 and an amplifier 40 to an ADC 41. Similarly, the IR. signal is provided through a second channel of filter 42, amplifier 43 and ADC 44. The analog output is obtained from the IR
signal at the input of ADC 44.
Demodulation in Software in the Present Invention [0021] Fig. 3 shows an embodiment of the present invention where demodulation isn't done in hardware, rather in software, so an analog IR signal simply is not available in hardware. A
signal from a patient sensor is processed in hardware through a current-to-voltage converter 45 and a filter 46, then is supplied to an ADC 47. In software, a demodulator separates the red and IR signals. The red signal is then provided to a software filter 49 and further processing not shown. The IR signal is similarly provided through a software filter 50 and further processing not shown. Since the software filtering can cause a significant time delay, the IR signal before the filter 50 is converted back into analog form. A.sigma-delta modulator 51 is used as a simple Digital-to-analog Converter (ADC). By using a sigma-delta modulator, the conversion process is simple and can be done quickly. The resulting analog signal then only needs to be filtered in a simple RC filter 52.
Sigma-delta Modulator and Filter for Simple DAC
[0022] Fig. 4 is a block diagram of a delta-sigma modulator 51 of Fig. 3 according to an embodiment of the invention. This modulator is preferably implemented in software running on microcontroller 22 of Fig. 1. An input on line 52 is the digitized sensor signal. In a preferred embodiment this signal is the infrared (IR) signal as opposed to the red signal. The infrared is chosen because it is typically a cleaner signal than the red signal. Fig. 4 is a graphical representation of the difference equations implemented to create the second order noise shaping for the quintile signal. In one implementation, pseudocode that implements the difference equations is:
X is the input on line 52 Y is the output on line 54 A, B, and C are intermediate variables that store data from one iteration to the next loop every 206pS
A = X ¨ C + (2 * B) C=B
if A > 1/2 thenY = 1 else Y = 0 end if B = A - Y
end loop This code is executed in a loop that executes every 206pS, so the output (Y) is a 4845 bits/sec bit stream with an average value that is equal to the input (X).
[0023] The output on line 54 is preferably a 4845 Hz bitstream.
This is provided to the input 60 of a hardware filter as shown in Fig. 5. This filter includes resistors 62 and 64 and capacitors 66 and 68. This filter acts on the digital output signal to convert it into analog form to produce an output on line 70 that can be provided to a display. The filter is a passive, second order RC filter, without a buffer on the output. Any buffering could be done by the host system before displaying, if required.
[0024] Fig. 6 shows an example of an analog display 72 on a pulse oximeter monitor 74.
The signal for this display is provided from line 70 of Fig. 5.
[0025] As will be understood by those of skill in the art, the present invention may be embodied in other specific forms without departing from the essential characteristics thereof For example, the delta-sigma modulator could be of a different order than a second order. Some filtering could be done in software prior to the hardware filter, and a different configuration of the hardware filter could be used. Accordingly, the foregoing description is intended to be illustrative, but not limiting. The scope of the claims should not be limited by the preferred embodiments set forth in the examples, but should be given the broadest interpretation consistent with the description as a whole.
[0011a] Accordingly, there is provided a method for operating a physiological monitor comprising: detecting an analog signal from a patient, wherein the analog signal comprises a physiological waveform; converting the analog signal into a digital signal;
demodulating the digital signal to produce at least two demodulated physiological signals;
applying one of the demodulated physiological signals to a delta-sigma modulator to provide an output signal; and filtering said output signal to provide a real-time analog filtered physiological waveform output.
[0011b] There is also provided a physiological monitor apparatus comprising:
an input for receiving from a patient an analog signal including a physiological waveform; an analog-to-digital converter for converting said analog signal into digital signal; a demodulator for demodulating the digital signal to produce at least two demodulated physiological signals; a delta-sigma modulator configured to convert one said demodulated physiological signals from digital into analog form; and a filter coupled to an output of said delta-sigma modulator.
2a ' [0012] For a further understanding of the nature and advantages of the invention, reference should be made to the following description taken in conjunction with the accompanying drawings.
BRIEF DESCRIPTION OF THE DRAWINGS
[0013] Fig. 1 is a block diagram of an oximeter incorporating the present invention.
[0014] Fig. 2 is a block diagram of a prior art circuit for generating an analog output signal.
[0015] Fig. 3 is a block diagram of an embodiment of a circuit for generating an analog output signal according to the present invention.
[0016] Fig. 4 is a block diagram of the software delta-sigma modulator according to an embodiment of the present invention.
[0017] Fig. 5 is a circuit diagram of an embodiment of the hardware RC filter according to an embodiment of the present invention.
[0018] Fig. 6 is a front view of a monitor showing an analog display according to an embodiment of the present invention.
DETAILED DESCRIPTION OF THE INVENTION
Overall System [0019] Fig. 1 illustrates an embodiment of an oximetry system incorporating the present invention. A sensor 10 includes red and infrared LEDs and a photodetector.
These are connected by a cable 12 to a board 14. LED drive current is provided by an LED
drive interface 16. The received photocurrent from the sensor is provided to an I-V
interface 18.
The IR and red voltages are then provided to a sigma-delta interface 20 incorporating the present invention. The output of sigma-delta interface 20 is provided to a microcontroller 22.
Microcontroller 22 includes flash memory for a program, and RAM memory for data. The oximeter also includes a microprocessor chip 24 connected to a flash memory 26. Finally, a clock 28 is used and an interface 30 to a digital calibration in the sensor 10 is provided. A
separate host 32 receives the processed information, as well as receiving an analog signal on a line 34 for providing an analog display.
Prior Art Demodulation in Hardware [0020] Fig. 2 shows an example of a prior art circuit for generating an analog output signal.
A signal from a patient sensor is processed in hardware through a current-to-voltage converter (I-V) 36, and a filter 37. The red and IR signals are then demodulated in a demodulator 38. A red signal is provided through a first channel of a filter 39 and an amplifier 40 to an ADC 41. Similarly, the IR. signal is provided through a second channel of filter 42, amplifier 43 and ADC 44. The analog output is obtained from the IR
signal at the input of ADC 44.
Demodulation in Software in the Present Invention [0021] Fig. 3 shows an embodiment of the present invention where demodulation isn't done in hardware, rather in software, so an analog IR signal simply is not available in hardware. A
signal from a patient sensor is processed in hardware through a current-to-voltage converter 45 and a filter 46, then is supplied to an ADC 47. In software, a demodulator separates the red and IR signals. The red signal is then provided to a software filter 49 and further processing not shown. The IR signal is similarly provided through a software filter 50 and further processing not shown. Since the software filtering can cause a significant time delay, the IR signal before the filter 50 is converted back into analog form. A.sigma-delta modulator 51 is used as a simple Digital-to-analog Converter (ADC). By using a sigma-delta modulator, the conversion process is simple and can be done quickly. The resulting analog signal then only needs to be filtered in a simple RC filter 52.
Sigma-delta Modulator and Filter for Simple DAC
[0022] Fig. 4 is a block diagram of a delta-sigma modulator 51 of Fig. 3 according to an embodiment of the invention. This modulator is preferably implemented in software running on microcontroller 22 of Fig. 1. An input on line 52 is the digitized sensor signal. In a preferred embodiment this signal is the infrared (IR) signal as opposed to the red signal. The infrared is chosen because it is typically a cleaner signal than the red signal. Fig. 4 is a graphical representation of the difference equations implemented to create the second order noise shaping for the quintile signal. In one implementation, pseudocode that implements the difference equations is:
X is the input on line 52 Y is the output on line 54 A, B, and C are intermediate variables that store data from one iteration to the next loop every 206pS
A = X ¨ C + (2 * B) C=B
if A > 1/2 thenY = 1 else Y = 0 end if B = A - Y
end loop This code is executed in a loop that executes every 206pS, so the output (Y) is a 4845 bits/sec bit stream with an average value that is equal to the input (X).
[0023] The output on line 54 is preferably a 4845 Hz bitstream.
This is provided to the input 60 of a hardware filter as shown in Fig. 5. This filter includes resistors 62 and 64 and capacitors 66 and 68. This filter acts on the digital output signal to convert it into analog form to produce an output on line 70 that can be provided to a display. The filter is a passive, second order RC filter, without a buffer on the output. Any buffering could be done by the host system before displaying, if required.
[0024] Fig. 6 shows an example of an analog display 72 on a pulse oximeter monitor 74.
The signal for this display is provided from line 70 of Fig. 5.
[0025] As will be understood by those of skill in the art, the present invention may be embodied in other specific forms without departing from the essential characteristics thereof For example, the delta-sigma modulator could be of a different order than a second order. Some filtering could be done in software prior to the hardware filter, and a different configuration of the hardware filter could be used. Accordingly, the foregoing description is intended to be illustrative, but not limiting. The scope of the claims should not be limited by the preferred embodiments set forth in the examples, but should be given the broadest interpretation consistent with the description as a whole.
Claims (34)
PROPERTY OR PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:
1. A method for operating a physiological monitor comprising:
detecting an analog signal from a patient, wherein the analog signal comprises a physiological waveform;
converting the analog signal into a digital signal;
demodulating the digital signal to produce at least two demodulated physiological signals;
applying one of the demodulated physiological signals to a delta-sigma modulator to provide an output signal; and filtering said output signal to provide a real-time analog filtered physiological waveform output.
detecting an analog signal from a patient, wherein the analog signal comprises a physiological waveform;
converting the analog signal into a digital signal;
demodulating the digital signal to produce at least two demodulated physiological signals;
applying one of the demodulated physiological signals to a delta-sigma modulator to provide an output signal; and filtering said output signal to provide a real-time analog filtered physiological waveform output.
2. The method of claim 1, wherein said filtering is performed by a hardware filter coupled to an output of said delta-sigma modulator.
3. The method of claim 1 or 2, wherein said delta-sigma modulator provides a single bit output.
4. The method of any one of claims 1 to 3, wherein the physiological waveform comprises a representation of an IR signal returned from a physiological sensor and a red signal returned from a physiological sensor.
5. The method of any one of claims 1 to 4, wherein the demodulated waveform comprises a representation of an IR signal received from a physiological sensor.
6. The method of any one of claims 1 to 5, wherein the delta-sigma modulator is configured to provide second order noise shaping of the demodulated physiological signals.
7. The method of any one of claims 1 to 6, wherein the delta-sigma modulator is configured to output a serial bit stream having a given frequency.
8. The method of claim 2, wherein the hardware filter comprises an RC filter.
9. The method of any one of claims 1 to 8, further comprising digitally filtering of one of the demodulated physiological signals to provide a first digital output signal.
10. The method of any one of claims 1 to 9, further comprising digitally filtering of the other one of the demodulated physiological signals to provide a second digital output signal.
11. A physiological monitor apparatus comprising:
an input for receiving from a patient an analog signal including a physiological waveform;
an analog-to-digital converter for converting said analog signal into digital signal;
a demodulator for demodulating the digital signal to produce at least two demodulated physiological signals;
a delta-sigma modulator configured to convert one said demodulated physiological signals from digital into analog form; and a filter coupled to an output of said delta-sigma modulator.
an input for receiving from a patient an analog signal including a physiological waveform;
an analog-to-digital converter for converting said analog signal into digital signal;
a demodulator for demodulating the digital signal to produce at least two demodulated physiological signals;
a delta-sigma modulator configured to convert one said demodulated physiological signals from digital into analog form; and a filter coupled to an output of said delta-sigma modulator.
12. The physiological monitor apparatus of claim 11, wherein said delta-sigma modulator is a software modulator that produces a serial, single bit output.
13. The physiological monitor apparatus of claim 11, wherein said filter is a hardware RC filter.
14. The physiological monitor apparatus of claim 11, further comprising at least one of a first digital filter for filtering the at least other one of the demodulated physiological signals and a second digital filter for filtering the at least one of the demodulated physiological signals.
15. The physiological monitor apparatus according to any one of claims 11 to l4, wherein the physiological monitor apparatus is an oximeter apparatus; the physiological waveform is a pulse oximetry waveform; the processor includes a demodulator for separating said waveform into red and IR signals, wherein the delta-sigma modulator is a software delta-sigma modulator being configured to convert one of said red and IR signals in digital form back into an analog by producing a serial, single bit output;
and wherein the filter is a hardware RC filter coupled to an output of said delta-sigma modulator for filtering said waveform.
and wherein the filter is a hardware RC filter coupled to an output of said delta-sigma modulator for filtering said waveform.
16. A method for operating a physiological monitor comprising:
detecting an analog signal from a patient, wherein the analog signal comprises at least one modulated physiological waveform;
converting the analog signal into a digital signal;
demodulating the digital signal to produce at least two demodulated physiological signals;
applying at least one of the demodulated physiological signals to a delta-sigma modulator to provide at least one physiological waveform; and filtering the at least one physiological waveform to provide a real-time analog filtered physiological waveform output, wherein the analog filtered physiological waveform is real-time relative to the time of detecting the analog signal from the patient to the time of providing the analog filtered physiological waveform output.
detecting an analog signal from a patient, wherein the analog signal comprises at least one modulated physiological waveform;
converting the analog signal into a digital signal;
demodulating the digital signal to produce at least two demodulated physiological signals;
applying at least one of the demodulated physiological signals to a delta-sigma modulator to provide at least one physiological waveform; and filtering the at least one physiological waveform to provide a real-time analog filtered physiological waveform output, wherein the analog filtered physiological waveform is real-time relative to the time of detecting the analog signal from the patient to the time of providing the analog filtered physiological waveform output.
17. The method of claim 16, wherein filtering at least one physiological waveform comprises passing the at least one physiological waveform through a hardware filter.
18. The method of claim 16 or 17, wherein the delta-sigma modulator is configured to provide a single bit output.
19. The method of claim 16, 17 or 18, wherein the at least one modulated physiological waveform comprises a representation of an IR signal returned from a physiological sensor and a red signal returned from a physiological sensor.
20. The method of any one of claims 16 to 19, wherein converting the analog signal into a digital signal comprises passing the analog signal through an analog-to-digital converter (ADC).
21. The method of any one of claims 1 to 20, wherein the demodulated waveform comprises a representation of an IR signal received from a physiological sensor.
22. The method of any one of claims 16 to 21, wherein the delta-sigma modulator is configured to provide second order noise shaping of the demodulated physiological signals.
23. The method of any one of claims 16 to 22, wherein the delta-sigma modulator is configured to output a serial bit stream having a given frequency.
24. The method of claim 17, wherein the hardware filter comprises an RC
filter.
filter.
25. A method for operating an oximeter comprising:
detecting an analog signal from a patient, wherein the analog signal comprises at least one pulse oximetry waveform;
converting the analog signal into a digital signal;
demodulating the digital signal to produce a red signal and an IR signal;
applying one of the red signal and the IR signal to a software delta-sigma modulator, wherein the software delta sigma modulator is configured to provide a single bit, serial output; and filtering the single bit, serial output with a hardware filter to provide a real-time analog waveform output, wherein the analog waveform is real-time relative to the time of detecting the analog signal from the patient to the time of providing the analog filtered physiological waveform output.
detecting an analog signal from a patient, wherein the analog signal comprises at least one pulse oximetry waveform;
converting the analog signal into a digital signal;
demodulating the digital signal to produce a red signal and an IR signal;
applying one of the red signal and the IR signal to a software delta-sigma modulator, wherein the software delta sigma modulator is configured to provide a single bit, serial output; and filtering the single bit, serial output with a hardware filter to provide a real-time analog waveform output, wherein the analog waveform is real-time relative to the time of detecting the analog signal from the patient to the time of providing the analog filtered physiological waveform output.
26. The method of claim 25, wherein the at least one pulse oximetry waveform comprises a representation of an IR signal returned from a physiological sensor or a red signal returned from a physiological sensor.
27. The method of claim 25 or 26, comprising configuring the software delta-sigma modulator to provide second order noise shaping of one of the red signal and the IR
signal.
signal.
28. The method of claim 25, 26 or 27, wherein the hardware filter comprises an RC filter.
29. A physiological monitor apparatus comprising:
an input configured to receive an analog signal from a patient, wherein the analog signal comprises a physiological waveform;
an analog-to-digital converter configured to convert the analog signal into a digital form of the physiological waveform;
a processor including a delta-sigma modulator configured to convert the digital form of the physiological waveform into an analog form of the physiological waveform, and wherein the delta-sigma modulator is configured to output the analog form of the physiological waveform; and a filter configured to receive and filter the analog form of the physiological waveform and to output a real-time waveform, wherein the real-time waveform is real-time relative to the time analog signal received from the patient to the time the real-time waveform is output.
an input configured to receive an analog signal from a patient, wherein the analog signal comprises a physiological waveform;
an analog-to-digital converter configured to convert the analog signal into a digital form of the physiological waveform;
a processor including a delta-sigma modulator configured to convert the digital form of the physiological waveform into an analog form of the physiological waveform, and wherein the delta-sigma modulator is configured to output the analog form of the physiological waveform; and a filter configured to receive and filter the analog form of the physiological waveform and to output a real-time waveform, wherein the real-time waveform is real-time relative to the time analog signal received from the patient to the time the real-time waveform is output.
30. The physiological monitor apparatus of claim 29, wherein the delta-sigma modulator comprises a software modulator that produces a serial, single bit output.
31. The physiological monitor apparatus of claim 29 or 30, wherein the filter is a hardware RC filter.
32. The physiological monitor method of claim 29, wherein the delta-sigma modulator is configured to output a serial bit stream having a given frequency.
33. An oximeter apparatus comprising:
an input configured to receive a signal, wherein the signal comprises a pulse oximetry waveform, and wherein the pulse oximetry waveform is representative of data gathered from a sensor coupled to a patient;
an analog-to-digital converter configured to convert the pulse oximetry waveform into a digital form of the pulse oximetry waveform;
a processor, comprising:
a demodulator configured to separate the digital form of the pulse oximetry waveform into a red digital signal and an IR digital signal; and a software delta-sigma modulator configured to convert one of the red digital signal and the IR digital signal into an analog signal, wherein the analog signal is a serial, single bit output;
a hardware RC filter configured to filter the serial, single bit output of the software delta-sigma modulator and to output a filtered signal in real-time, wherein the filtered signal is real-time relative to the time the input receives the signal to the time the filtered signal is output; and an output configured to provide the real-time filtered signal to a host.
an input configured to receive a signal, wherein the signal comprises a pulse oximetry waveform, and wherein the pulse oximetry waveform is representative of data gathered from a sensor coupled to a patient;
an analog-to-digital converter configured to convert the pulse oximetry waveform into a digital form of the pulse oximetry waveform;
a processor, comprising:
a demodulator configured to separate the digital form of the pulse oximetry waveform into a red digital signal and an IR digital signal; and a software delta-sigma modulator configured to convert one of the red digital signal and the IR digital signal into an analog signal, wherein the analog signal is a serial, single bit output;
a hardware RC filter configured to filter the serial, single bit output of the software delta-sigma modulator and to output a filtered signal in real-time, wherein the filtered signal is real-time relative to the time the input receives the signal to the time the filtered signal is output; and an output configured to provide the real-time filtered signal to a host.
34. The method of claim 33, wherein the serial, single bit output has a given frequency.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/787,853 | 2004-02-25 | ||
| US10/787,853 US7212847B2 (en) | 2004-02-25 | 2004-02-25 | Delta-sigma modulator for outputting analog representation of physiological signal |
| PCT/US2005/005934 WO2005082237A1 (en) | 2004-02-25 | 2005-02-24 | Delta-sigma modulator for outputting analog representation of physiological signal |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2556755A1 CA2556755A1 (en) | 2005-09-09 |
| CA2556755C true CA2556755C (en) | 2013-06-11 |
Family
ID=34861936
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2556755A Active CA2556755C (en) | 2004-02-25 | 2005-02-24 | Delta-sigma modulator for outputting analog representation of physiological signal |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7212847B2 (en) |
| EP (1) | EP1729630B1 (en) |
| JP (1) | JP4705626B2 (en) |
| KR (1) | KR20070029676A (en) |
| CN (1) | CN1933770A (en) |
| AT (1) | ATE468807T1 (en) |
| AU (1) | AU2005216959A1 (en) |
| CA (1) | CA2556755C (en) |
| DE (1) | DE602005021470D1 (en) |
| ES (1) | ES2344112T3 (en) |
| MX (1) | MXPA06009749A (en) |
| WO (1) | WO2005082237A1 (en) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7761127B2 (en) | 2005-03-01 | 2010-07-20 | Masimo Laboratories, Inc. | Multiple wavelength sensor substrate |
| KR100791634B1 (en) | 2006-09-29 | 2008-01-04 | 고려대학교 산학협력단 | Delta-sigma modulator with reduced power consumption and pacemaker using this |
| US8157730B2 (en) | 2006-12-19 | 2012-04-17 | Valencell, Inc. | Physiological and environmental monitoring systems and methods |
| US8652040B2 (en) | 2006-12-19 | 2014-02-18 | Valencell, Inc. | Telemetric apparatus for health and environmental monitoring |
| US20080221418A1 (en) * | 2007-03-09 | 2008-09-11 | Masimo Corporation | Noninvasive multi-parameter patient monitor |
| EP2139383B1 (en) | 2007-03-27 | 2013-02-13 | Masimo Laboratories, Inc. | Multiple wavelength optical sensor |
| US8374665B2 (en) | 2007-04-21 | 2013-02-12 | Cercacor Laboratories, Inc. | Tissue profile wellness monitor |
| US7818638B2 (en) * | 2007-06-15 | 2010-10-19 | Micron Technology, Inc. | Systems and devices including memory with built-in self test and methods of making and using the same |
| US8251903B2 (en) | 2007-10-25 | 2012-08-28 | Valencell, Inc. | Noninvasive physiological analysis using excitation-sensor modules and related devices and methods |
| US7782237B2 (en) * | 2008-06-13 | 2010-08-24 | The Board Of Trustees Of The Leland Stanford Junior University | Semiconductor sensor circuit arrangement |
| US20100004518A1 (en) | 2008-07-03 | 2010-01-07 | Masimo Laboratories, Inc. | Heat sink for noninvasive medical sensor |
| US8630691B2 (en) | 2008-08-04 | 2014-01-14 | Cercacor Laboratories, Inc. | Multi-stream sensor front ends for noninvasive measurement of blood constituents |
| US8788002B2 (en) | 2009-02-25 | 2014-07-22 | Valencell, Inc. | Light-guiding devices and monitoring devices incorporating same |
| US9750462B2 (en) * | 2009-02-25 | 2017-09-05 | Valencell, Inc. | Monitoring apparatus and methods for measuring physiological and/or environmental conditions |
| JP5789199B2 (en) | 2009-02-25 | 2015-10-07 | ヴァレンセル，インコーポレイテッド | Headset and earbud |
| US8840562B2 (en) * | 2009-09-24 | 2014-09-23 | Covidien Lp | Signal processing warping technique |
| US8571621B2 (en) * | 2009-09-24 | 2013-10-29 | Covidien Lp | Minimax filtering for pulse oximetry |
| US9839381B1 (en) | 2009-11-24 | 2017-12-12 | Cercacor Laboratories, Inc. | Physiological measurement system with automatic wavelength adjustment |
| DE112010004682T5 (en) | 2009-12-04 | 2013-03-28 | Masimo Corporation | Calibration for multi-level physiological monitors |
| US8888701B2 (en) | 2011-01-27 | 2014-11-18 | Valencell, Inc. | Apparatus and methods for monitoring physiological data during environmental interference |
| WO2013016007A2 (en) | 2011-07-25 | 2013-01-31 | Valencell, Inc. | Apparatus and methods for estimating time-state physiological parameters |
| WO2013019494A2 (en) | 2011-08-02 | 2013-02-07 | Valencell, Inc. | Systems and methods for variable filter adjustment by heart rate metric feedback |
| EP2928364A4 (en) | 2013-01-28 | 2015-11-11 | Valencell Inc | Physiological monitoring devices having sensing elements decoupled from body motion |
| JP5830120B2 (en) * | 2014-03-20 | 2015-12-09 | 日本光電工業株式会社 | Method and apparatus for upgrading biological information monitor |
| US9538921B2 (en) | 2014-07-30 | 2017-01-10 | Valencell, Inc. | Physiological monitoring devices with adjustable signal analysis and interrogation power and monitoring methods using same |
| EP4098178B1 (en) | 2014-08-06 | 2024-04-10 | Yukka Magic LLC | Optical physiological sensor modules with reduced signal noise |
| US9794653B2 (en) | 2014-09-27 | 2017-10-17 | Valencell, Inc. | Methods and apparatus for improving signal quality in wearable biometric monitoring devices |
| US9743868B2 (en) * | 2014-11-20 | 2017-08-29 | Qualcomm Incorporated | Circuitry to allow low current operation of a device capable of determining a blood property |
| US10945618B2 (en) | 2015-10-23 | 2021-03-16 | Valencell, Inc. | Physiological monitoring devices and methods for noise reduction in physiological signals based on subject activity type |
| WO2017070463A1 (en) | 2015-10-23 | 2017-04-27 | Valencell, Inc. | Physiological monitoring devices and methods that identify subject activity type |
| WO2018009736A1 (en) | 2016-07-08 | 2018-01-11 | Valencell, Inc. | Motion-dependent averaging for physiological metric estimating systems and methods |
| KR101933009B1 (en) * | 2017-01-03 | 2019-03-15 | 아주대학교산학협력단 | Light to digital convertor |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US803910A (en) * | 1904-07-20 | 1905-11-07 | Leo Ledermann | Floating device. |
| US4802486A (en) | 1985-04-01 | 1989-02-07 | Nellcor Incorporated | Method and apparatus for detecting optical pulses |
| US4911167A (en) | 1985-06-07 | 1990-03-27 | Nellcor Incorporated | Method and apparatus for detecting optical pulses |
| US4928692A (en) | 1985-04-01 | 1990-05-29 | Goodman David E | Method and apparatus for detecting optical pulses |
| US4934372A (en) | 1985-04-01 | 1990-06-19 | Nellcor Incorporated | Method and apparatus for detecting optical pulses |
| US4873987A (en) * | 1988-06-30 | 1989-10-17 | Ljubomir Djordjevich | Noninvasive continuous monitor of arterial blood pressure waveform |
| US5061925A (en) * | 1990-08-22 | 1991-10-29 | Crystal Semiconductor Corporation | Phase equalization system for a digital-to-analog converter utilizing separate digital and analog sections |
| MX9702434A (en) | 1991-03-07 | 1998-05-31 | Masimo Corp | Signal processing apparatus. |
| US5632272A (en) * | 1991-03-07 | 1997-05-27 | Masimo Corporation | Signal processing apparatus |
| US5351685A (en) | 1991-08-05 | 1994-10-04 | Nellcor Incorporated | Condensed oximeter system with noise reduction software |
| US5934277A (en) | 1991-09-03 | 1999-08-10 | Datex-Ohmeda, Inc. | System for pulse oximetry SpO2 determination |
| AU648925B2 (en) * | 1991-10-21 | 1994-05-05 | Matsushita Electric Industrial Co., Ltd. | Electrolytic capacitor and method for producing the same |
| US5368224A (en) | 1992-10-23 | 1994-11-29 | Nellcor Incorporated | Method for reducing ambient noise effects in electronic monitoring instruments |
| DE69312425T2 (en) * | 1992-11-09 | 1998-02-12 | Philips Electronics Nv | Digital / analog converter |
| US5368026A (en) | 1993-03-26 | 1994-11-29 | Nellcor Incorporated | Oximeter with motion detection for alarm modification |
| US5424655A (en) * | 1994-05-20 | 1995-06-13 | Quicklogic Corporation | Programmable application specific integrated circuit employing antifuses and methods therefor |
| US5638816A (en) | 1995-06-07 | 1997-06-17 | Masimo Corporation | Active pulse blood constituent monitoring |
| AUPN740796A0 (en) | 1996-01-04 | 1996-01-25 | Circuitry Systems Limited | Biomedical data collection apparatus |
| US5746697A (en) | 1996-02-09 | 1998-05-05 | Nellcor Puritan Bennett Incorporated | Medical diagnostic apparatus with sleep mode |
| US5921921A (en) | 1996-12-18 | 1999-07-13 | Nellcor Puritan-Bennett | Pulse oximeter with sigma-delta converter |
| US5995858A (en) | 1997-11-07 | 1999-11-30 | Datascope Investment Corp. | Pulse oximeter |
| US6226539B1 (en) | 1999-05-26 | 2001-05-01 | Mallinckrodt, Inc. | Pulse oximeter having a low power led drive |
| US6707407B2 (en) * | 2001-06-11 | 2004-03-16 | Analog Devices, Inc. | Method for converting a video signal from one of an analogue and digital form to the other of the analogue and digital form with enhanced signal to noise ratio |
| US6850788B2 (en) * | 2002-03-25 | 2005-02-01 | Masimo Corporation | Physiological measurement communications adapter |
| US6924756B2 (en) * | 2003-05-28 | 2005-08-02 | Texas Instruments Incorporated | Method and system for processing a digital signal |
-
2004
- 2004-02-25 US US10/787,853 patent/US7212847B2/en active Active
-
2005
- 2005-02-24 ES ES05714036T patent/ES2344112T3/en active Active
- 2005-02-24 DE DE602005021470T patent/DE602005021470D1/en active Active
- 2005-02-24 JP JP2007500978A patent/JP4705626B2/en active Active
- 2005-02-24 CA CA2556755A patent/CA2556755C/en active Active
- 2005-02-24 AU AU2005216959A patent/AU2005216959A1/en not_active Abandoned
- 2005-02-24 AT AT05714036T patent/ATE468807T1/en not_active IP Right Cessation
- 2005-02-24 WO PCT/US2005/005934 patent/WO2005082237A1/en active Application Filing
- 2005-02-24 KR KR1020067019096A patent/KR20070029676A/en not_active Application Discontinuation
- 2005-02-24 MX MXPA06009749A patent/MXPA06009749A/en not_active Application Discontinuation
- 2005-02-24 CN CNA2005800058567A patent/CN1933770A/en active Pending
- 2005-02-24 EP EP05714036A patent/EP1729630B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP4705626B2 (en) | 2011-06-22 |
| CA2556755A1 (en) | 2005-09-09 |
| ES2344112T3 (en) | 2010-08-18 |
| JP2007523728A (en) | 2007-08-23 |
| EP1729630B1 (en) | 2010-05-26 |
| KR20070029676A (en) | 2007-03-14 |
| AU2005216959A1 (en) | 2005-09-09 |
| MXPA06009749A (en) | 2007-03-15 |
| ATE468807T1 (en) | 2010-06-15 |
| EP1729630A1 (en) | 2006-12-13 |
| US20050187453A1 (en) | 2005-08-25 |
| CN1933770A (en) | 2007-03-21 |
| US7212847B2 (en) | 2007-05-01 |
| WO2005082237A1 (en) | 2005-09-09 |
| DE602005021470D1 (en) | 2010-07-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2556755C (en) | Delta-sigma modulator for outputting analog representation of physiological signal | |
| CA2556748C (en) | Oximeter ambient light cancellation | |
| CA2260928C (en) | Direct to digital oximeter | |
| US7403806B2 (en) | System for prefiltering a plethysmographic signal | |
| US9380969B2 (en) | Systems and methods for varying a sampling rate of a signal | |
| US7725147B2 (en) | System and method for removing artifacts from waveforms | |
| US6381479B1 (en) | Pulse oximeter with improved DC and low frequency rejection | |
| Patterson et al. | Ratiometric artifact reduction in low power reflective photoplethysmography | |
| US20120245441A1 (en) | Signal demodulation | |
| US8909312B2 (en) | Signal acquisition circuit for detecting a wanted signal in the presence of an unwanted signal | |
| JP4399847B2 (en) | Pulse oximeter | |
| Patterson et al. | Ratiometric artefact reduction in low power, discrete-time, reflective photoplethysmography |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |