CA2554746C - Sanitizing and cleaning composition and its use for sanitizing and/or cleaning hard surfaces - Google Patents
Sanitizing and cleaning composition and its use for sanitizing and/or cleaning hard surfaces Download PDFInfo
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- CA2554746C CA2554746C CA2554746A CA2554746A CA2554746C CA 2554746 C CA2554746 C CA 2554746C CA 2554746 A CA2554746 A CA 2554746A CA 2554746 A CA2554746 A CA 2554746A CA 2554746 C CA2554746 C CA 2554746C
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- acid
- sanitizing
- cleaning
- acidic
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- 238000011012 sanitization Methods 0.000 title claims abstract description 116
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- 125000004432 carbon atom Chemical group C* 0.000 claims description 18
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- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- DUWWHGPELOTTOE-UHFFFAOYSA-N n-(5-chloro-2,4-dimethoxyphenyl)-3-oxobutanamide Chemical compound COC1=CC(OC)=C(NC(=O)CC(C)=O)C=C1Cl DUWWHGPELOTTOE-UHFFFAOYSA-N 0.000 description 1
- ZBJVLWIYKOAYQH-UHFFFAOYSA-N naphthalen-2-yl 2-hydroxybenzoate Chemical compound OC1=CC=CC=C1C(=O)OC1=CC=C(C=CC=C2)C2=C1 ZBJVLWIYKOAYQH-UHFFFAOYSA-N 0.000 description 1
- 235000019645 odor Nutrition 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 159000000001 potassium salts Chemical class 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 238000004064 recycling Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 229940079842 sodium cumenesulfonate Drugs 0.000 description 1
- 229940048842 sodium xylenesulfonate Drugs 0.000 description 1
- QUCDWLYKDRVKMI-UHFFFAOYSA-M sodium;3,4-dimethylbenzenesulfonate Chemical compound [Na+].CC1=CC=C(S([O-])(=O)=O)C=C1C QUCDWLYKDRVKMI-UHFFFAOYSA-M 0.000 description 1
- KVCGISUBCHHTDD-UHFFFAOYSA-M sodium;4-methylbenzenesulfonate Chemical compound [Na+].CC1=CC=C(S([O-])(=O)=O)C=C1 KVCGISUBCHHTDD-UHFFFAOYSA-M 0.000 description 1
- QEKATQBVVAZOAY-UHFFFAOYSA-M sodium;4-propan-2-ylbenzenesulfonate Chemical compound [Na+].CC(C)C1=CC=C(S([O-])(=O)=O)C=C1 QEKATQBVVAZOAY-UHFFFAOYSA-M 0.000 description 1
- DAJSVUQLFFJUSX-UHFFFAOYSA-M sodium;dodecane-1-sulfonate Chemical compound [Na+].CCCCCCCCCCCCS([O-])(=O)=O DAJSVUQLFFJUSX-UHFFFAOYSA-M 0.000 description 1
- 150000003444 succinic acids Chemical class 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 235000019640 taste Nutrition 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/0005—Other compounding ingredients characterised by their effect
- C11D3/0047—Other compounding ingredients characterised by their effect pH regulated compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D11/00—Special methods for preparing compositions containing mixtures of detergents ; Methods for using cleaning compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/02—Inorganic compounds ; Elemental compounds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/02—Inorganic compounds ; Elemental compounds
- C11D3/04—Water-soluble compounds
- C11D3/042—Acids
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/2075—Carboxylic acids-salts thereof
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
-
- C11D2111/20—
Abstract
The present invention relates to acidic sanitizing and/or cleaning compositions comprising a specific quaternary antimicrobial system consisting of C1-C4 hydroxyalkyl carboxylic acids, C5-C18 alkyl monocarboxylic acids, unsubstituted or substituted, saturated or unsaturated C4-dicarboxylic acids and additional inorganic or organic acids. The compositions of the present invention can be present in the form of concentrates and in the form of diluted use solutions. They can be used in a process for sanitizing and/or cleaning hard surfaces, preferably in a cleaning-in-place (CIP) and/or sanitize-in-place (SIP) process for cleaning and/or sanitizing plants in the food, dairy, beverage, brewery and soft drink industries.
Description
SANITIZING AND CLEANING COMPOSITION UND ITS USE FOR
SANITIZING AND/OR CLEANING HARD SURFACES
FIELD OF THE INVENTION
The present invention relates to acidic sanitizing and/or cleaning compositions comprising a specific antimicrobial quaternary system consisting of CI-C4 hydroxyalkyl carboxylic acids, C5-C18 alkyl monocarboxylic acids, un-substituted or substituted, saturated or unsaturated C4 dicarboxylic acids and additional inorganic or organic acids. The compositions of the present invention can be present in the form of concentrates and in the form of diluted use solutions. They can be used in a process for sanitizing and/or cleaning hard surfaces, preferably in a cleaning-in-place (CIP) and/or sanitizing-in-place (SIP) process for cleaning and/or sanitizing plants in the food, dairy, beverage, brewery and soft drink industries.
BACKGROUND OF THE INVENTION
Periodic cleaning and sanitizing in dairy, food and beverage industries, in food preparation and service businesses are a necessary practice for product quality and public health. Residuals left on equipment surfaces or contaminants found in the process or service environment can promote growth of microorganisms. Protecting the consumer against potential health hazards associated with pathogens or toxins and maintaining the quality of the product or service requires routine removing of residuals from surfaces and effective sanitation to reduce microbial populations.
Visual inspection of the equipment cannot ensure that surfaces are clean or free of microorganisms. Antimicrobial treatments as well as cleaning treatments are therefore required for all critical surfaces in order to reduce microbial population to safe levels established by public health regulations.
This process is generally referred to as sanitizing. The practice of sanitation is particularly of concern in food process facilities wherein the cleaning treatment is followed by an antimicrobial treatment applied upon all critical surfaces and environmental surfaces to reduce the microbial population to safe levels established by ordinance. A sanitized surface is, as defined by the Environmental Protection Agency (EPA), a consequence of a process or program containing both an initial cleaning and a subsequent sanitizing treatment which must be separated by a potable water rinse. A sanitizing treatment applied to a cleaned food contact surface must result in a reduction in population of at least 99.999 % (5 log) for specified microorganisms as defined by the "Germicidal and Detergent Sanitizing Action of Disinfectants", Official Methods of Analysis of the Association of Official Analytical Chemists, paragraph 960.09 and applicable sections,l5th Edition, 1990 (EPA Guideline 91-2).
The antimicrobial efficacy of sanitizing treatments is significantly reduced if the surface is not absolutely free of soil and other contaminants prior to the sanitizing step. The presence of residual food soil and/or mineral deposits inhibit sanitizing treatments by acting as physical barriers which shield microorganisms lying within the organic or inorganic layer from the microbicide. Furthermore, chemical interactions between the microbicide and certain contaminants can disrupt the killing mechanism of the microbicide.
With the advent of automated cleaning-in-place (CIP) and sanitize-in-place (SIP) systems, the need for disassembly has been diminished, and cleaning and sanitizing have become much more effective. However, modern food industries still rely on sanitizers to compensate for design deficiencies or operational limitations in their cleaning programs and the probability of very small residual amounts of organic and inorganic soils and biofilms remaining on food contact surfaces after cleaning. In cooperation with these process changes and higher performance expectations, sanitizer treatments must also comply with the increasing demand for safer, less corrosive, more environmentally friendly compositions.
Therefore, a need exists for improving sanitizing treatments to destroy pathogens and food spoilage microorganisms resistant to conventional treatments within the food gathering, food processing, and food serving industries. Various chemicals exhibiting varying degrees of antimicrobial activity have been used in sanitizing operations. Among these are short-chain monocarboxylic acids having less than 20 carbon atoms, quaternary ammonium compounds and hexachlorophene compounds. These compounds have been admixed with various surfactants and water to yield aqueous sanitizing solutions. Sanitizers containing halogen can be corrosive to metal surfaces of food plants and quaternary ammonium compounds which also have been used, strongly adhere to sanitized surfaces even after copious rinsing and may interfere with desired microbial growth during food processing, e.g. fermentation.
On the other hand, one problem associated with the use of short-chain monocarboxylic acids sanitizers is poor use dilution phase stability, particularly at lower water temperatures of 0 to 10 C. Fatty monocarboxylic acids having alkyl chains containing 5 or more carbon atoms, are typically characterized as water insoluble and can oil out or precipitate from solution as a gelatinous flocculant. Solubility tends to decrease with decreasing water temperature and increasing ionic concentration. Furthermore, the oil or precipitate can affix to the very surfaces which the sanitizing solution is intended to sanitize, such as equipment surfaces, leading to a film formation on these surfaces over time. The fatty acid film deposited and left remaining on the equipment surface tends to have a higher pH than the sanitizing solution from which it came resulting in a significantly lowered biocidal efficacy, and, if mixed with food soil, may result in a film matrix which has the potential of harboring bacteria, an effect opposite to that desired.
Furthermore, antimicrobial solutions containing these" antimicrobial agents are undesirable for use in food equipment cleaning applications.
Residual amounts of the acidic sanitizing solutions which remain in the equipment after cleaning can impart unpleasant tastes and odors to food. The cleaning compositions are difficult to rinse from the cleaned surfaces. Larger amounts of water are required to completely remove conventional sanitizing solutions.
It has been found that antimicrobial activity of acidic sanitizing solutions as defined above can be increased by acidifying the sanitizer solution to a pH below 5, so that acidic sanitizing solutions of this type are generally used in food, beverage, brewery and other industries as a cleaning-in-place (CIP) and/or sanitize-in-place (SIP) solution for processing equipment. While the acidic sanitizing solutions presently available are effective against gram-negative and gra m-positive bacterias such as Escherichia coli and Staphylococcus au reus, they are not as efficacious on any yeast or mold contamination which can also be present. In many applications control of yeast infections requires a separate solution that can be costly and time consuming.
Such antimicrobiological solutions are generally produced by admixture of water and an aqueous concentrate containing antimicrobiological agents, water or other diluents and acids capable of yielding a pH below about 5 upon dilutions. However, it is clear that such antimicrobial compositions must also exhibit homogeneity and solution stability during prolonged storage periods, in particular at low temperatures. In order to achieve this, solubilizers or coupling agents are added to the compositions in order to maintain stability of the solu-tion at high acid concentrations at prolonged low temperatures or during re-peated freeze/thaw cycles.
Such solubilizers are generally surfactant hydrotropes capable of solu-bilizing the antimicrobial agent in the acidic concentrate which maintain it in both the concentrate and the diluted antimicrobial solution suitable for con-ventional use. For this purpose various anionic, zwitterionic and nonionic sur-factants or mixtures thereof have been previously employed in such solutions.
However, these solubilizers, when used in antimicrobial compositions, tend to cause undesirable foaming, thus requiring the addition of foam suppressants for the CIP application and SIP application. Additionally, these solubilizers do not provide stability over a wide range of storage temperatures.
Therefore, there is a need for providing a stable antimicrobial composition which can provide an antimicrobial solution which is equally 5 effective on gram-negative and gram-positive microorganisms and on yeast and on mould, and the antimicrobial activity of which is uneffected by water hardness and which also provides a low foaming antimicrobial use solution capable of removing intense flavour for instance of soft drinks and which is less corrosive and more environmentally friendly.
Now it has been surprisingly found that this need can be satisfied by a specific antimicrobial sanitizing and/or cleaning composition capable of being diluted with a major amount of a food grade diluent to form an antimicrobial use solution.
SUMMARY OF THE INVENTION
Subject-matter of the present invention is according lo its first aspect an acidic sanitizing and/or cleaning composition capable of being diluted to form an acidic sanitizing and/or cleaning use solution, the composition comprising:
a) a quaternary antimicrobial system comprising at least one C1-C4 hydroxy alkyl carboxylic acid or salt thereof, at least one C5-C18 alkyl monocarboxylic acid having the general formula:
R"' - COOH
wherein R"' is a straight or branched, saturated or unsaturated alkyl moiety having from about 5 to about 18, preferably from about 6 to about 12 carbon atoms; or salt thereof, at least one dicarboxylic acid having the general formula:
0 (R')n' 0 II I II
HO-C-R-C-OH
(R")nõ
wherein R is a saturated or unsaturated hyd rocarbon moiety having 2 carbon atoms; R' is hydrogen, hydroxyl, a substituted or unsubsti-tuted n-alkyl or n-alkenyl moiety having from about I to about 12, preferably from about 6 to about 12 carbon atoms, where suitable substituents of R' comprise thiol, methane thiol, amine, methoxy and aryl substituents and n' and n" each are an integer of from 0 to 4; and R" represents hydrogen or hy-droxyl; or salt or anhydride thereof;
at least one acid capable of yielding a pH of about <_ 5.0 upon di-lution of the composition to a use solution, b) at least one solubilizer;
c) at least one diluent, preferably water; and d) optionally at least one detergent.
The above acidic sanitizing and/or cleaning composition can be diluted to form an acidic sanitizing and/or cleaning use solution which is equally ef-fective on gram-negative and gram-positive microorganisms and on yeast and on mould, and the antimicrobial activity of which is uneffacted by water hard-ness. The composition of the present invention also provides a low foaming antimicrobial use solution capable of removing intense flavour, e.g. of soft drinks, and being less corrosive and more environmentally friendly than the antimicrobial use solutions of the prior art.
Preferred embodiments of the sanitizing and/or cleaning composition of the present invention are, singly or in any combination, those wherein:
SANITIZING AND/OR CLEANING HARD SURFACES
FIELD OF THE INVENTION
The present invention relates to acidic sanitizing and/or cleaning compositions comprising a specific antimicrobial quaternary system consisting of CI-C4 hydroxyalkyl carboxylic acids, C5-C18 alkyl monocarboxylic acids, un-substituted or substituted, saturated or unsaturated C4 dicarboxylic acids and additional inorganic or organic acids. The compositions of the present invention can be present in the form of concentrates and in the form of diluted use solutions. They can be used in a process for sanitizing and/or cleaning hard surfaces, preferably in a cleaning-in-place (CIP) and/or sanitizing-in-place (SIP) process for cleaning and/or sanitizing plants in the food, dairy, beverage, brewery and soft drink industries.
BACKGROUND OF THE INVENTION
Periodic cleaning and sanitizing in dairy, food and beverage industries, in food preparation and service businesses are a necessary practice for product quality and public health. Residuals left on equipment surfaces or contaminants found in the process or service environment can promote growth of microorganisms. Protecting the consumer against potential health hazards associated with pathogens or toxins and maintaining the quality of the product or service requires routine removing of residuals from surfaces and effective sanitation to reduce microbial populations.
Visual inspection of the equipment cannot ensure that surfaces are clean or free of microorganisms. Antimicrobial treatments as well as cleaning treatments are therefore required for all critical surfaces in order to reduce microbial population to safe levels established by public health regulations.
This process is generally referred to as sanitizing. The practice of sanitation is particularly of concern in food process facilities wherein the cleaning treatment is followed by an antimicrobial treatment applied upon all critical surfaces and environmental surfaces to reduce the microbial population to safe levels established by ordinance. A sanitized surface is, as defined by the Environmental Protection Agency (EPA), a consequence of a process or program containing both an initial cleaning and a subsequent sanitizing treatment which must be separated by a potable water rinse. A sanitizing treatment applied to a cleaned food contact surface must result in a reduction in population of at least 99.999 % (5 log) for specified microorganisms as defined by the "Germicidal and Detergent Sanitizing Action of Disinfectants", Official Methods of Analysis of the Association of Official Analytical Chemists, paragraph 960.09 and applicable sections,l5th Edition, 1990 (EPA Guideline 91-2).
The antimicrobial efficacy of sanitizing treatments is significantly reduced if the surface is not absolutely free of soil and other contaminants prior to the sanitizing step. The presence of residual food soil and/or mineral deposits inhibit sanitizing treatments by acting as physical barriers which shield microorganisms lying within the organic or inorganic layer from the microbicide. Furthermore, chemical interactions between the microbicide and certain contaminants can disrupt the killing mechanism of the microbicide.
With the advent of automated cleaning-in-place (CIP) and sanitize-in-place (SIP) systems, the need for disassembly has been diminished, and cleaning and sanitizing have become much more effective. However, modern food industries still rely on sanitizers to compensate for design deficiencies or operational limitations in their cleaning programs and the probability of very small residual amounts of organic and inorganic soils and biofilms remaining on food contact surfaces after cleaning. In cooperation with these process changes and higher performance expectations, sanitizer treatments must also comply with the increasing demand for safer, less corrosive, more environmentally friendly compositions.
Therefore, a need exists for improving sanitizing treatments to destroy pathogens and food spoilage microorganisms resistant to conventional treatments within the food gathering, food processing, and food serving industries. Various chemicals exhibiting varying degrees of antimicrobial activity have been used in sanitizing operations. Among these are short-chain monocarboxylic acids having less than 20 carbon atoms, quaternary ammonium compounds and hexachlorophene compounds. These compounds have been admixed with various surfactants and water to yield aqueous sanitizing solutions. Sanitizers containing halogen can be corrosive to metal surfaces of food plants and quaternary ammonium compounds which also have been used, strongly adhere to sanitized surfaces even after copious rinsing and may interfere with desired microbial growth during food processing, e.g. fermentation.
On the other hand, one problem associated with the use of short-chain monocarboxylic acids sanitizers is poor use dilution phase stability, particularly at lower water temperatures of 0 to 10 C. Fatty monocarboxylic acids having alkyl chains containing 5 or more carbon atoms, are typically characterized as water insoluble and can oil out or precipitate from solution as a gelatinous flocculant. Solubility tends to decrease with decreasing water temperature and increasing ionic concentration. Furthermore, the oil or precipitate can affix to the very surfaces which the sanitizing solution is intended to sanitize, such as equipment surfaces, leading to a film formation on these surfaces over time. The fatty acid film deposited and left remaining on the equipment surface tends to have a higher pH than the sanitizing solution from which it came resulting in a significantly lowered biocidal efficacy, and, if mixed with food soil, may result in a film matrix which has the potential of harboring bacteria, an effect opposite to that desired.
Furthermore, antimicrobial solutions containing these" antimicrobial agents are undesirable for use in food equipment cleaning applications.
Residual amounts of the acidic sanitizing solutions which remain in the equipment after cleaning can impart unpleasant tastes and odors to food. The cleaning compositions are difficult to rinse from the cleaned surfaces. Larger amounts of water are required to completely remove conventional sanitizing solutions.
It has been found that antimicrobial activity of acidic sanitizing solutions as defined above can be increased by acidifying the sanitizer solution to a pH below 5, so that acidic sanitizing solutions of this type are generally used in food, beverage, brewery and other industries as a cleaning-in-place (CIP) and/or sanitize-in-place (SIP) solution for processing equipment. While the acidic sanitizing solutions presently available are effective against gram-negative and gra m-positive bacterias such as Escherichia coli and Staphylococcus au reus, they are not as efficacious on any yeast or mold contamination which can also be present. In many applications control of yeast infections requires a separate solution that can be costly and time consuming.
Such antimicrobiological solutions are generally produced by admixture of water and an aqueous concentrate containing antimicrobiological agents, water or other diluents and acids capable of yielding a pH below about 5 upon dilutions. However, it is clear that such antimicrobial compositions must also exhibit homogeneity and solution stability during prolonged storage periods, in particular at low temperatures. In order to achieve this, solubilizers or coupling agents are added to the compositions in order to maintain stability of the solu-tion at high acid concentrations at prolonged low temperatures or during re-peated freeze/thaw cycles.
Such solubilizers are generally surfactant hydrotropes capable of solu-bilizing the antimicrobial agent in the acidic concentrate which maintain it in both the concentrate and the diluted antimicrobial solution suitable for con-ventional use. For this purpose various anionic, zwitterionic and nonionic sur-factants or mixtures thereof have been previously employed in such solutions.
However, these solubilizers, when used in antimicrobial compositions, tend to cause undesirable foaming, thus requiring the addition of foam suppressants for the CIP application and SIP application. Additionally, these solubilizers do not provide stability over a wide range of storage temperatures.
Therefore, there is a need for providing a stable antimicrobial composition which can provide an antimicrobial solution which is equally 5 effective on gram-negative and gram-positive microorganisms and on yeast and on mould, and the antimicrobial activity of which is uneffected by water hardness and which also provides a low foaming antimicrobial use solution capable of removing intense flavour for instance of soft drinks and which is less corrosive and more environmentally friendly.
Now it has been surprisingly found that this need can be satisfied by a specific antimicrobial sanitizing and/or cleaning composition capable of being diluted with a major amount of a food grade diluent to form an antimicrobial use solution.
SUMMARY OF THE INVENTION
Subject-matter of the present invention is according lo its first aspect an acidic sanitizing and/or cleaning composition capable of being diluted to form an acidic sanitizing and/or cleaning use solution, the composition comprising:
a) a quaternary antimicrobial system comprising at least one C1-C4 hydroxy alkyl carboxylic acid or salt thereof, at least one C5-C18 alkyl monocarboxylic acid having the general formula:
R"' - COOH
wherein R"' is a straight or branched, saturated or unsaturated alkyl moiety having from about 5 to about 18, preferably from about 6 to about 12 carbon atoms; or salt thereof, at least one dicarboxylic acid having the general formula:
0 (R')n' 0 II I II
HO-C-R-C-OH
(R")nõ
wherein R is a saturated or unsaturated hyd rocarbon moiety having 2 carbon atoms; R' is hydrogen, hydroxyl, a substituted or unsubsti-tuted n-alkyl or n-alkenyl moiety having from about I to about 12, preferably from about 6 to about 12 carbon atoms, where suitable substituents of R' comprise thiol, methane thiol, amine, methoxy and aryl substituents and n' and n" each are an integer of from 0 to 4; and R" represents hydrogen or hy-droxyl; or salt or anhydride thereof;
at least one acid capable of yielding a pH of about <_ 5.0 upon di-lution of the composition to a use solution, b) at least one solubilizer;
c) at least one diluent, preferably water; and d) optionally at least one detergent.
The above acidic sanitizing and/or cleaning composition can be diluted to form an acidic sanitizing and/or cleaning use solution which is equally ef-fective on gram-negative and gram-positive microorganisms and on yeast and on mould, and the antimicrobial activity of which is uneffacted by water hard-ness. The composition of the present invention also provides a low foaming antimicrobial use solution capable of removing intense flavour, e.g. of soft drinks, and being less corrosive and more environmentally friendly than the antimicrobial use solutions of the prior art.
Preferred embodiments of the sanitizing and/or cleaning composition of the present invention are, singly or in any combination, those wherein:
said at least one C1-C4-hydroxy alkyl carboxylic acid (a) is an a-hydroxy carboxylic acid selected from the group consisting of glycolic acid, lactic acid, hydroxy propanoic acid, dihydroxy propanoic acid, hydroxy butyric acid, and mixtures thereof;
said at least one C5-C18 alkyl monocarboxylic acid ((3) is selected from the group consisting of pentanoic acid, hexanoic acid, heptanoic acid, oc-tanoic acid, nonanoic acid, decanoic acid, undecanoic acid, dodecanoic acid, tridecanoic acid, tetradecanoic acid, pentadecanoic acid, hexadecanoic acid, heptadecanoic acid, octadecanoic acid, neodecanoic acid, 2,2-dimethyloctanoic acid and mixtures thereof;
said dicarboxylic acid (y) is selected from the group consisting of tar-taric acid, maleic acid, fumaric acid, succinic acid, n-octyl succinic acid, n-octenyl succinic acid, n-nonyl succinic acid, n-nonenyl succinic acid, n-decyl succinic acid, n-decenyl succinic acid, n-hexyl succinic acid, n-hexenyl succinic acid, diisobutenyl succinic acid, methyl heptenyl succinic acid and mixtures thereof; preferably is n-octenyl and/or n-nonenyl Si L Jnic acid(s);
said acid (S) is an organic acid, preferably an organic acid selected from the group consisting of formic acid, acetic acid, citric acid, and alkyl sul-fonic acid, preferably methyl sulfonic acid and mixtures thereof; or an inor-ganic acid, preferably an inorganic acid selected from the group consisting of phosphoric acid, sulfuric acid, nitric acid (preferably in combination with a small amount (preferably about 1 wt.%) of urea to prevent NO, formation), hydrochloric acid, sulfamic acid and mixtures thereof, more preferably, said acid (6) is selected from the group consisting of phosphoric acid, nitric acid, sulfuric acid, methyl sulfonic acid and mixtures thereof;
the mono- and dicarboxylic acids (13, y) are present in'a weight ratio of between about 1 : 1 and about 1 : 20, preferably between about 1 : 2 and about 1:10;
said at least one solubilizer (b) is a surfactant-hydrotrope selected from the group consisting of anionic surfactants, nonionic surfactants, zwitterionic surfactants and mixtures thereof;
the anionic surfactant is selected from the group consisting of alkyl sul-fonates and alkylaryl sulfonates having about 8 to about 22, preferably about 8 to about 18 carbon atoms in the alkyl portion, ammoniurn, alkali metal or alkaline earth metal salts or mixtures thereof, preferably it is sodium or potas-sium alkyl benzene sulfonate, sodium or potassium xylene sulfonate, sodium or potassium cumene sulfonate or sodium or potassium toluene sulfonate;
the zwitterionic surfactant is selected from the group consisting of alky-limidazolines, alkylamines and mixtures thereof;
the nonionic surfactant is selected from the group consisting of ethyl-ene oxide adducts of C8 to C22, preferably C8 to C16, more preferably C8 to alcohols, ethylene oxide/propylene oxide adducts of ethylene glycol, alkylene glycols or mixtures thereof;
said at least one diluent is selected from any food grade diluent, preferably water and short chain alcohols having 2 to 5 carbon atoms, most preferably is potable water;
said C1-C4-hydroxyalkyl carboxylic acid (a) is present in an amount of from about 0.25 to 15, preferably from about 1 to 10, more preferably from about 2 to 8, most preferably from about 3 to 5 wt.%, based on the total amount of the composition;
said C5-C18 alkyl monocarboxylic acid (1i) is present in an amount of from about 0.1 to 5, preferably from about 0.3 to 4, most preferably from about 0.5 to 2.0 wt.%, based on the total amount of the composition;
said dicarboxylic acid (y) is present in an amount of from about 0.1 to 8, preferably from about 0.5 to 6, most preferably from about 1 to 4.5 wt.%, based on the total amount of the composition;
said acid (8) is present in an amount of from about 4.0 to about 60.0, preferably from about 10 to 40 wt.%, based on the total amount of the composition;
said diluent (c) is present in an amount of from about 10 to about 95.5, preferably from about 15 to 90 wt.%, based on the total amount of the composition;
said detergent (d) is present in an amount of from about 5 to 30, preferably from about 10 to 25 wt.%, based on the total weight of the concentrate;
said composition is diluted with water in a ratio of from about 1 : 10 to about 1 : 500, preferably from about 1 : 30 to about 1 : 400 and more preferably from about 1 : 50 to about 1 : 100 parts of composition to diluent (c).
Subject-matter of the present invention is, according to a second as-pect, also a low foaming acidic sanitizing and/or clean ing use solution com-prising:
a) a quaternary antimicrobial system comprising at least one C1-C4 hydroxy alkyl carboxylic acid or salt thereof, at least one C5-C18 alkyl monocarboxylic acid having the general formula:
R"'-COON
wherein R"' is a straight or branched, saturated or unsaturated alkyl moiety having from about 5 to about 18, preferably from about 6 to about 12 carbon atoms; or salt thereof, at least one dicarboxylic acid having the general formula:
0 (R')õ' 0 HO-C-R-C-OH
(R")n"
wherein R is a saturated or unsaturated hydrocarbon moiety having 2 carbon atoms; R' is hydrogen, hydroxyl, a substituted or unsubsti-tuted n-alkyl or n-alkenyl moiety having from about 1 to about 12, preferably from about 6 to about 12 carbon atoms, where suitable substituents of R' comprise thiol, methane thiol, amine, methoxy and aryl substituents and n' and n" each are an integer of from 0 to 4; and R" represents hydrogen or hy-droxyl; or salt or anhydride thereof;
at least one acid capable of yielding a pH of about <_ 5.0 upon di-lution of the composition to the use solution, b) at least one solubilizer;
c) at least one diluent, preferably water; and d) optionally at least one detergent.
The sanitizing and/or cleaning use solution as defined above can be prepared by diluting the sanitizing and/or cleaning composition according to the present invention with a food grade diluent, preferably potable water, in a ratio of from about 1:10 to about 1 : 500, preferably from about 1 : 30 to about 1 : 400 and more preferably from about 1 : 50 to about 1 : 100 parts of composition to diluent.
A preferred embodiment of the use solution of the present invention is a low foaming, acidic antimicrobial sanitizing and/or cleaning use solution prepared by diluting the composition as defined above with potable water in such ratio, that it comprises:
a) between about 1 about 5000 ppm, preferably from about 5 to about 3000, most preferably from about 10 to about 1500 ppm of the antimicrobial system (a - y);
said at least one C5-C18 alkyl monocarboxylic acid ((3) is selected from the group consisting of pentanoic acid, hexanoic acid, heptanoic acid, oc-tanoic acid, nonanoic acid, decanoic acid, undecanoic acid, dodecanoic acid, tridecanoic acid, tetradecanoic acid, pentadecanoic acid, hexadecanoic acid, heptadecanoic acid, octadecanoic acid, neodecanoic acid, 2,2-dimethyloctanoic acid and mixtures thereof;
said dicarboxylic acid (y) is selected from the group consisting of tar-taric acid, maleic acid, fumaric acid, succinic acid, n-octyl succinic acid, n-octenyl succinic acid, n-nonyl succinic acid, n-nonenyl succinic acid, n-decyl succinic acid, n-decenyl succinic acid, n-hexyl succinic acid, n-hexenyl succinic acid, diisobutenyl succinic acid, methyl heptenyl succinic acid and mixtures thereof; preferably is n-octenyl and/or n-nonenyl Si L Jnic acid(s);
said acid (S) is an organic acid, preferably an organic acid selected from the group consisting of formic acid, acetic acid, citric acid, and alkyl sul-fonic acid, preferably methyl sulfonic acid and mixtures thereof; or an inor-ganic acid, preferably an inorganic acid selected from the group consisting of phosphoric acid, sulfuric acid, nitric acid (preferably in combination with a small amount (preferably about 1 wt.%) of urea to prevent NO, formation), hydrochloric acid, sulfamic acid and mixtures thereof, more preferably, said acid (6) is selected from the group consisting of phosphoric acid, nitric acid, sulfuric acid, methyl sulfonic acid and mixtures thereof;
the mono- and dicarboxylic acids (13, y) are present in'a weight ratio of between about 1 : 1 and about 1 : 20, preferably between about 1 : 2 and about 1:10;
said at least one solubilizer (b) is a surfactant-hydrotrope selected from the group consisting of anionic surfactants, nonionic surfactants, zwitterionic surfactants and mixtures thereof;
the anionic surfactant is selected from the group consisting of alkyl sul-fonates and alkylaryl sulfonates having about 8 to about 22, preferably about 8 to about 18 carbon atoms in the alkyl portion, ammoniurn, alkali metal or alkaline earth metal salts or mixtures thereof, preferably it is sodium or potas-sium alkyl benzene sulfonate, sodium or potassium xylene sulfonate, sodium or potassium cumene sulfonate or sodium or potassium toluene sulfonate;
the zwitterionic surfactant is selected from the group consisting of alky-limidazolines, alkylamines and mixtures thereof;
the nonionic surfactant is selected from the group consisting of ethyl-ene oxide adducts of C8 to C22, preferably C8 to C16, more preferably C8 to alcohols, ethylene oxide/propylene oxide adducts of ethylene glycol, alkylene glycols or mixtures thereof;
said at least one diluent is selected from any food grade diluent, preferably water and short chain alcohols having 2 to 5 carbon atoms, most preferably is potable water;
said C1-C4-hydroxyalkyl carboxylic acid (a) is present in an amount of from about 0.25 to 15, preferably from about 1 to 10, more preferably from about 2 to 8, most preferably from about 3 to 5 wt.%, based on the total amount of the composition;
said C5-C18 alkyl monocarboxylic acid (1i) is present in an amount of from about 0.1 to 5, preferably from about 0.3 to 4, most preferably from about 0.5 to 2.0 wt.%, based on the total amount of the composition;
said dicarboxylic acid (y) is present in an amount of from about 0.1 to 8, preferably from about 0.5 to 6, most preferably from about 1 to 4.5 wt.%, based on the total amount of the composition;
said acid (8) is present in an amount of from about 4.0 to about 60.0, preferably from about 10 to 40 wt.%, based on the total amount of the composition;
said diluent (c) is present in an amount of from about 10 to about 95.5, preferably from about 15 to 90 wt.%, based on the total amount of the composition;
said detergent (d) is present in an amount of from about 5 to 30, preferably from about 10 to 25 wt.%, based on the total weight of the concentrate;
said composition is diluted with water in a ratio of from about 1 : 10 to about 1 : 500, preferably from about 1 : 30 to about 1 : 400 and more preferably from about 1 : 50 to about 1 : 100 parts of composition to diluent (c).
Subject-matter of the present invention is, according to a second as-pect, also a low foaming acidic sanitizing and/or clean ing use solution com-prising:
a) a quaternary antimicrobial system comprising at least one C1-C4 hydroxy alkyl carboxylic acid or salt thereof, at least one C5-C18 alkyl monocarboxylic acid having the general formula:
R"'-COON
wherein R"' is a straight or branched, saturated or unsaturated alkyl moiety having from about 5 to about 18, preferably from about 6 to about 12 carbon atoms; or salt thereof, at least one dicarboxylic acid having the general formula:
0 (R')õ' 0 HO-C-R-C-OH
(R")n"
wherein R is a saturated or unsaturated hydrocarbon moiety having 2 carbon atoms; R' is hydrogen, hydroxyl, a substituted or unsubsti-tuted n-alkyl or n-alkenyl moiety having from about 1 to about 12, preferably from about 6 to about 12 carbon atoms, where suitable substituents of R' comprise thiol, methane thiol, amine, methoxy and aryl substituents and n' and n" each are an integer of from 0 to 4; and R" represents hydrogen or hy-droxyl; or salt or anhydride thereof;
at least one acid capable of yielding a pH of about <_ 5.0 upon di-lution of the composition to the use solution, b) at least one solubilizer;
c) at least one diluent, preferably water; and d) optionally at least one detergent.
The sanitizing and/or cleaning use solution as defined above can be prepared by diluting the sanitizing and/or cleaning composition according to the present invention with a food grade diluent, preferably potable water, in a ratio of from about 1:10 to about 1 : 500, preferably from about 1 : 30 to about 1 : 400 and more preferably from about 1 : 50 to about 1 : 100 parts of composition to diluent.
A preferred embodiment of the use solution of the present invention is a low foaming, acidic antimicrobial sanitizing and/or cleaning use solution prepared by diluting the composition as defined above with potable water in such ratio, that it comprises:
a) between about 1 about 5000 ppm, preferably from about 5 to about 3000, most preferably from about 10 to about 1500 ppm of the antimicrobial system (a - y);
b) from about 5 to about 10 000, preferably from about 10 to about 5000 ppm of the solubilizer (b) and c) a sufficient amount of the acid (6) to yield a pH below about 5.0, preferably from 4.5 to 1.0, d) optionally a sufficient amount of the detergent (d) to induce surface wetting and soil removal and (e) water as the balance of the composition.
A further subject-matter of the present invention is according to a third aspect a process for sanitizing and/or cleaning a hard surface, preferably a cleaning-in-place (CIP) and/or sanitize-in-place (SIP) process for cleaning and/or sanitizing plants in the food, dairy, beverage, brewery and soft drink industries, the process being carried out by contacting a low foaming acidic, aqueous, antimicrobial use solution as defined above at a temperature of from 0 to 80 C, preferably from 5 to 60 C, with the hard sou; mace to be cleaned and/or santized for about 30 s to about 20 min, preferably for about 1 to about 5 min, draining off the use solution with or without recycling it and finally rinsing the hard surface with potable water.
Further details of the present invention are as follows where it is to be considered that the type and the amount of the stated components of the composition and of the use solution of the present invention may be varied in such manner that antimicrobial sanitizing and/or cleaning compositions are obtained which have the desired characteristics and lead to the desired ef-fects.
1) The quaternary antimicrobial system being one of the essential components of the sanitizing and/or cleaning composition of the present in-vention comprises:
a Cl-C4 hydroxyalkyl carboxylic acid, preferably an a-C, to C4 hydroxyalkyl carboxylic acid. Examples of suitable hydroxyalkyl carboxylic acids include, but are not limited to, hydroxy propanoic acid, dihydroxy pro-panoic acid, hydroxy citric acid, hydroxy butyric acid, tartaric acid, glycolic acid, lactic acid and mixtures thereof;
a C5 to C18 alkyl mono carboxylic acid, preferably a C6 to C12 al-kyl mono carboxylic acid. Its alkyl residue may be straight or branched, satu-rated or unsaturated;
the dicarboxylic acids usable in the present invention are those having a saturated or unsaturated C1-C4-carbon back bone. Specifically, the substituted dicarboxylic acids employed herein are selected from the group consisting of maleic acid and fumaric acid and, preferably, succinic acid. The particularly preferred succinic acids employed in the present invention are selected from the group consisting of n-octyl succinic acid, n-octenyl succinic acid, n-nonyl succinic acid, n-nonenyl succinic acid, n-decyl succinic acid, n-decenyl succinic acid, n-hexyl succinic acid, n-hexenyl succinc acid, diisobu-tenyl succinic acid, methyl heptenyl succinic acid and mixtures thereof. Most preferably n-octenyl succinic acid and/or n-nonyl succinic acid(s) is (are) em-ployed;
the antimicrobial system of the present invention also contains an acid capable of providing a solution pH at or below about 5.0 when the composition is diluted to its use solution strength. The used acid must be compatible with the other components of the sanitizing solution, i.e. must not induce instability or cause undue degradation of a surfactant or organic acids.
This acid may be either a weak organic acid such as formic acid, acetic acid, citric acid, tartaric acid, maleic acid, fumaric acid or mixtures thereof or a stronger organic acid such as alkylsulfonic acid, preferably methylsulfonic acid or an inorganic acid such as phosphoric acid, sulfuric acid, nitric acid (preferably in combination with a small amount (about 1 wt.%) of urea to pre-vent NO,, formation), hydrochloric acid, sulfamic acid or mixtures thereof.
Preferably, phosphoric acid, nitric acid, sulfuric acid, and methylsulfonic acid are used.
A further subject-matter of the present invention is according to a third aspect a process for sanitizing and/or cleaning a hard surface, preferably a cleaning-in-place (CIP) and/or sanitize-in-place (SIP) process for cleaning and/or sanitizing plants in the food, dairy, beverage, brewery and soft drink industries, the process being carried out by contacting a low foaming acidic, aqueous, antimicrobial use solution as defined above at a temperature of from 0 to 80 C, preferably from 5 to 60 C, with the hard sou; mace to be cleaned and/or santized for about 30 s to about 20 min, preferably for about 1 to about 5 min, draining off the use solution with or without recycling it and finally rinsing the hard surface with potable water.
Further details of the present invention are as follows where it is to be considered that the type and the amount of the stated components of the composition and of the use solution of the present invention may be varied in such manner that antimicrobial sanitizing and/or cleaning compositions are obtained which have the desired characteristics and lead to the desired ef-fects.
1) The quaternary antimicrobial system being one of the essential components of the sanitizing and/or cleaning composition of the present in-vention comprises:
a Cl-C4 hydroxyalkyl carboxylic acid, preferably an a-C, to C4 hydroxyalkyl carboxylic acid. Examples of suitable hydroxyalkyl carboxylic acids include, but are not limited to, hydroxy propanoic acid, dihydroxy pro-panoic acid, hydroxy citric acid, hydroxy butyric acid, tartaric acid, glycolic acid, lactic acid and mixtures thereof;
a C5 to C18 alkyl mono carboxylic acid, preferably a C6 to C12 al-kyl mono carboxylic acid. Its alkyl residue may be straight or branched, satu-rated or unsaturated;
the dicarboxylic acids usable in the present invention are those having a saturated or unsaturated C1-C4-carbon back bone. Specifically, the substituted dicarboxylic acids employed herein are selected from the group consisting of maleic acid and fumaric acid and, preferably, succinic acid. The particularly preferred succinic acids employed in the present invention are selected from the group consisting of n-octyl succinic acid, n-octenyl succinic acid, n-nonyl succinic acid, n-nonenyl succinic acid, n-decyl succinic acid, n-decenyl succinic acid, n-hexyl succinic acid, n-hexenyl succinc acid, diisobu-tenyl succinic acid, methyl heptenyl succinic acid and mixtures thereof. Most preferably n-octenyl succinic acid and/or n-nonyl succinic acid(s) is (are) em-ployed;
the antimicrobial system of the present invention also contains an acid capable of providing a solution pH at or below about 5.0 when the composition is diluted to its use solution strength. The used acid must be compatible with the other components of the sanitizing solution, i.e. must not induce instability or cause undue degradation of a surfactant or organic acids.
This acid may be either a weak organic acid such as formic acid, acetic acid, citric acid, tartaric acid, maleic acid, fumaric acid or mixtures thereof or a stronger organic acid such as alkylsulfonic acid, preferably methylsulfonic acid or an inorganic acid such as phosphoric acid, sulfuric acid, nitric acid (preferably in combination with a small amount (about 1 wt.%) of urea to pre-vent NO,, formation), hydrochloric acid, sulfamic acid or mixtures thereof.
Preferably, phosphoric acid, nitric acid, sulfuric acid, and methylsulfonic acid are used.
2) The solubilizer used in the present invention is a surfactant hy-drotrope capable of solubilizing the alkyl monocarboxylic acid and the dicar-boxylic acid in an acidic diluent while maintaining the monocarboxylic acid and the dicarboxylic acid in solubilized form in both the composition and the diluted use solution of the product under use conditions. Various anionic, zwit-terionic and nonionic surfactants or mixtures thereof can be used in the pre-sent invention.
Examples of the anionic surfactants which may be used in the present invention are alkyl sulfonates and alkylaryl sulfonates having from about 8 to about 22 carbon atoms in the alkyl portion, as well as the alkali metal salts thereof. Commercially important are the sodium and potassium salts of linear alkyl sulfonates such as sodium lauryl sulfonate and the potassium alkylben-zene sulfonates such as sodium xylenesulfonate, sodium cumenesulfonate, sodium toluenesulfonate.
Suitable zwitterionic surfactants are the alkyl imidazolines and al-kylamines marketed under the trademark MIRAPON by Miranol.
Examples of the nonionic surfactants which may be used in the com-positions of this invention are the ethylene oxide adducts and propylene oxide adducts of primary C8 to C22 alkanols sold commercially under the trade-names Berol by Akzo Nobel or Lutensol by BASF, and the ethoxylated and propoxylated types sold under the tradenames Plurafac by BASF.
The diluent which may be used is preferably potable water. However, also other compatible food grade diluents such as C2 to C5 alkanols, may also be used.
Additionally, the composition of the present invention may optionally include at least one anionic and/or nonionic surfactant. In some embodi-ments, a nonionic surfactant is suitably employed to improve surface wetting, soil removal, etc. It may also function to improve the solubility of the used fatty acids at use dilutions.
Examples of the anionic surfactants which may be used in the present invention are alkyl sulfonates and alkylaryl sulfonates having from about 8 to about 22 carbon atoms in the alkyl portion, as well as the alkali metal salts thereof. Commercially important are the sodium and potassium salts of linear alkyl sulfonates such as sodium lauryl sulfonate and the potassium alkylben-zene sulfonates such as sodium xylenesulfonate, sodium cumenesulfonate, sodium toluenesulfonate.
Suitable zwitterionic surfactants are the alkyl imidazolines and al-kylamines marketed under the trademark MIRAPON by Miranol.
Examples of the nonionic surfactants which may be used in the com-positions of this invention are the ethylene oxide adducts and propylene oxide adducts of primary C8 to C22 alkanols sold commercially under the trade-names Berol by Akzo Nobel or Lutensol by BASF, and the ethoxylated and propoxylated types sold under the tradenames Plurafac by BASF.
The diluent which may be used is preferably potable water. However, also other compatible food grade diluents such as C2 to C5 alkanols, may also be used.
Additionally, the composition of the present invention may optionally include at least one anionic and/or nonionic surfactant. In some embodi-ments, a nonionic surfactant is suitably employed to improve surface wetting, soil removal, etc. It may also function to improve the solubility of the used fatty acids at use dilutions.
The composition of the present invention is, as already mentioned, capable of forming a use solution by admixing the composition with an diluent such as water. The obtained use solution generally comprises:
a) from about 1 to about 10 000 parts per million (ppm) of the de-fined hydroxyalkyl carboxylic acid, b) from about 1 to about 1 000 ppm of the defined C5-C18 alkyl monocarboxylic acid c) from about 1 to about 1 000 ppm of the defined dicarboxylic acid, d) an organic or inorganic acid as defined above in an amount suf-ficient to yield a use solution pH of about _< 5.0, preferably 4.5 to 1.0, e) from about 10 to about 10 000 ppm of a solubilizer as defined above, f) water as the balance of the composition and g) optionally at least one anionic or nonionic detergent to improve surface wetting, soil removal etc.
The antimicrobial sanitizing composition of the present invention may be successfully employed for sanitizing and/or disinfecting fixed-in-place food processing facilities such as those of dairy, brewery and beverage plants. The composition of the present invention exhibits an antimicrobial activity at a temperature of from about 0 C to 80 C.
For carrying out sanitizing, the diluted use solution having a tempera-ture of from 0 to 80 C, preferably from 5 to 60 C, is circulated through the system for a period of time sufficient to contact and kill undesirable microor-ganisms. This time can be anywhere from less than 30 seconds to about 10 or 20 minutes depending on the type and amount of contamination present.
Preferably, the contact-time will be in the range of from about 1 to about 5 minutes. After sanitizing the composition is drained off from the system and the system is rinsed with potable water.
In most cleaning-in-place applications, the system can be brought back into service immediately after removal of the sanitizing solution. However, the system may also be rinsed with potable water or any other suitable material after sanitizing.
The sanitizing composition may be admixed with a detergent composi-tion to impart the additional sanitizing properties of this invention to a deter-gent when in use. For example detergents are routinely used in European countries to clean various facilities in food, dairy, brewery and beverage plants in order to avoid the need for a subsequent sanitizing rinse of the facil-ity. The sanitizing composition of the invention may also be used in other ways such as in track lubricants, teat dips and warewashing rinse aids. When the sanitizing composition is used in a detergent composition, appropriate surfactants are employed which preferably are those of the anionic or non-ionic low foaming type. It is clear that such surfactant has to be compatible with the sanitizing composition so as to avoid degradation or separation in the final product.
For a more complete understanding of the present invention, reference is made to the following examples. The examples are only to be considered as illustrative and not limitative to the present invention. All percentages are "wt. %".
EXAMPLES
Preparation of the compositions Each of the following compositions was prepared by admixing the in-gredients listed in the following table 1 in sequential order, blending thor-oughly by agitation and allowing each ingredient to completely disperse or dissolve in the liquid mixture before addition of the next ingredient. The resu I-tant compositions were clear and homogeneously uniform upon admixture of all listed ingredients. Compositions Al to A4 contained the quaternary antim-icrobial system of the present invention . Composition BI is a comparative acidic composition corresponding to a prior art represented by presently commercially available compositions fo r standard CIP applications.
Table 1 Composition Al A2 A3 A4 BI
softened Water (%) 38.0 41.0 35.0 35.0 15.0 phospate ester (%) 4.0 4.0 4.0 cumene sulfonate (%) 15.0 15.0 20.0 20.0 30.0 75 %-H3PO4 (%) - - 35.0 - 40.0 53 %-HNO3 (%) 30.0 30.0 - 35.0 -70 %-glycolic acid (%) 5.0 5.0 6.5 6.5 -octanoic acid (%) 2.0 2.0 1.0 1.0 2.0 N-octenyl succinic acid 6.0 3.0 2.5 2.5 9.0 (%) Test M ethods 1. Biocidal Efficacy Test Quantitative suspension testing for the evaluation of bactericidal and fungicidal activity of chemical disinfectants and antiseptics used in food, industrial, domestic and institutional areas was conducted according to EN
1276:1997 (bacteria) and EN 1650:199P7 (fungi), (CEN - European Committee for Standardization).
The tests were conducted with 0.25, 0.50, 1.00 and 4.00 % use solutions prepared from the compositio ns of table 1 by diluting them with water in a sufficient amount to obtain each of the use solutions, e.g. by m ixing 4 g of composition Al with 96 g water for obtaining the 4 wt.% use solution Al. For dilution standardised sterile hard water with 300 mg/kg CaCO3 was used. The samples were exposed at 2 O C to the challenge bacteria Lactobacillus brevis, the yeast Saccharomyces diastaticus a.:id the mould Aspergillus niger. The resulting data are presented in table 2.
As can been seen from the data in table 2 the compositions Al to A4 of the present invention containing the quaternary microbiocidal system show a significiant higher microbiocidal activity than the comparative composition B1, which corresponds to presently commercially available compositions for standard CIP in the industry. Even with half of the amount of octanoic acid (A3 and A4) or a third of the amount of N-octenyl succinic acid (A2, A3 and A4) the compositions Al to A4 of the present invention provide the same or better microorganism reduction rates compared to comparative composition BI under identical test conditions. Remarkable is in particular that compositions Al to A4 provided a 99% reduction for A. niger with 4% use solutions, which is the economical upper limit for a use solution while the comparative composition 131 failed.
Table 2 Composition Al A2 A3 A4:,'. 131 softened Water (%) 38.0 41.0 35.0 35.0 15.0 phosphate ester (%) 4.0 4.0 4.0 cumene sulfonate (%) 15.0 15.0 20.0 20.0 30.0 75 %-H3PO4 (%) - - 35.0 - 40.0 53 %-HNO3 (%) 30.0 30.0 - 35.0 -70 %-glycolic acid (%) 5.0 5.0 6.5 6.5 -octanoic acid (%) 2.0 2.0 1.0 1.0 2.0 N-octenyl succinic acid (%) 6.0 3.0 2.5 2.5 9.0 Microbiology minimal use concentration to pass the test A. niger 20 C passed passed passed passed failed 99 % reduction (4%) (4%) (4%) (4%) (4%) min contact time S. diastaticus 20 C passed passed passed passed passed 99.99 % reduction 0.25% 0.5% 1% 10/0 1%
15 min contact time L. brevis 20 C passed passed passed passed passed 99.999 % reduction 0.25% 0.5% 0.5% 0.5% 0.5%
5 min contact time 2. Foaming Evaluation 15 2 litre of a I % use solution was circulated with a flow rate of 1.8 I/s through a temperated 5.5 1 glass cylinder for 30 min to establish a foam/liquid equilibrium. The build-up of foam layer in cm was determined immediately at the end of a 30 min pumping period ("0") and 15 sec after switch off of the pump ("15").
Table 3 Composition Al Al A2 A2 A3 A3 A4 A4 131 BI
time [sec] 0 15 0 15 0 15 0 15 0 15 foam height [cm]
at 10 C 16 15 9 9 <1 0 <1 0 30 30 at 20 C 10 10 6 5 <1 0 <1 0 20 20 at 40 C 0 0 0 0 0 0 0 0 2 1 at 60 C 0 7 0 0 0 0 0 0 0 1 1 The above data clearly show that the quaternary system of the inven-tion leads to signifcant less or no foam, which is necessary for a CIP and/or SIP application compared to composition B1 representing the presently available commercially compositions for standard CIP and SIP applications.
3. Phase Separation (Stability) Test Using the compositions of table 1 0.5%, 1%, 2% and 3% use solutions were prepared as explained above and after conditioning at 20 C for 3 days they were visually inspected for physical instability.
"+" means stability (no phase separation);
will means instability (discernible phase separation).
Composition Al A2 A3 A4 BI
Concentration 0.5% + + + + +
1.0% + + + + -2.0% - + + + -Due to the possibility to reduce the amounts of microbiocidal agents (octanoic acid and N-octenyl succinic acid) the risk of phase separation ac-cording to the present invention is clearly lower. Therefore, higher concen-trated use solutions for CIP and SIP applications are usable without any risk of residues being left behind in the treated plant.
a) from about 1 to about 10 000 parts per million (ppm) of the de-fined hydroxyalkyl carboxylic acid, b) from about 1 to about 1 000 ppm of the defined C5-C18 alkyl monocarboxylic acid c) from about 1 to about 1 000 ppm of the defined dicarboxylic acid, d) an organic or inorganic acid as defined above in an amount suf-ficient to yield a use solution pH of about _< 5.0, preferably 4.5 to 1.0, e) from about 10 to about 10 000 ppm of a solubilizer as defined above, f) water as the balance of the composition and g) optionally at least one anionic or nonionic detergent to improve surface wetting, soil removal etc.
The antimicrobial sanitizing composition of the present invention may be successfully employed for sanitizing and/or disinfecting fixed-in-place food processing facilities such as those of dairy, brewery and beverage plants. The composition of the present invention exhibits an antimicrobial activity at a temperature of from about 0 C to 80 C.
For carrying out sanitizing, the diluted use solution having a tempera-ture of from 0 to 80 C, preferably from 5 to 60 C, is circulated through the system for a period of time sufficient to contact and kill undesirable microor-ganisms. This time can be anywhere from less than 30 seconds to about 10 or 20 minutes depending on the type and amount of contamination present.
Preferably, the contact-time will be in the range of from about 1 to about 5 minutes. After sanitizing the composition is drained off from the system and the system is rinsed with potable water.
In most cleaning-in-place applications, the system can be brought back into service immediately after removal of the sanitizing solution. However, the system may also be rinsed with potable water or any other suitable material after sanitizing.
The sanitizing composition may be admixed with a detergent composi-tion to impart the additional sanitizing properties of this invention to a deter-gent when in use. For example detergents are routinely used in European countries to clean various facilities in food, dairy, brewery and beverage plants in order to avoid the need for a subsequent sanitizing rinse of the facil-ity. The sanitizing composition of the invention may also be used in other ways such as in track lubricants, teat dips and warewashing rinse aids. When the sanitizing composition is used in a detergent composition, appropriate surfactants are employed which preferably are those of the anionic or non-ionic low foaming type. It is clear that such surfactant has to be compatible with the sanitizing composition so as to avoid degradation or separation in the final product.
For a more complete understanding of the present invention, reference is made to the following examples. The examples are only to be considered as illustrative and not limitative to the present invention. All percentages are "wt. %".
EXAMPLES
Preparation of the compositions Each of the following compositions was prepared by admixing the in-gredients listed in the following table 1 in sequential order, blending thor-oughly by agitation and allowing each ingredient to completely disperse or dissolve in the liquid mixture before addition of the next ingredient. The resu I-tant compositions were clear and homogeneously uniform upon admixture of all listed ingredients. Compositions Al to A4 contained the quaternary antim-icrobial system of the present invention . Composition BI is a comparative acidic composition corresponding to a prior art represented by presently commercially available compositions fo r standard CIP applications.
Table 1 Composition Al A2 A3 A4 BI
softened Water (%) 38.0 41.0 35.0 35.0 15.0 phospate ester (%) 4.0 4.0 4.0 cumene sulfonate (%) 15.0 15.0 20.0 20.0 30.0 75 %-H3PO4 (%) - - 35.0 - 40.0 53 %-HNO3 (%) 30.0 30.0 - 35.0 -70 %-glycolic acid (%) 5.0 5.0 6.5 6.5 -octanoic acid (%) 2.0 2.0 1.0 1.0 2.0 N-octenyl succinic acid 6.0 3.0 2.5 2.5 9.0 (%) Test M ethods 1. Biocidal Efficacy Test Quantitative suspension testing for the evaluation of bactericidal and fungicidal activity of chemical disinfectants and antiseptics used in food, industrial, domestic and institutional areas was conducted according to EN
1276:1997 (bacteria) and EN 1650:199P7 (fungi), (CEN - European Committee for Standardization).
The tests were conducted with 0.25, 0.50, 1.00 and 4.00 % use solutions prepared from the compositio ns of table 1 by diluting them with water in a sufficient amount to obtain each of the use solutions, e.g. by m ixing 4 g of composition Al with 96 g water for obtaining the 4 wt.% use solution Al. For dilution standardised sterile hard water with 300 mg/kg CaCO3 was used. The samples were exposed at 2 O C to the challenge bacteria Lactobacillus brevis, the yeast Saccharomyces diastaticus a.:id the mould Aspergillus niger. The resulting data are presented in table 2.
As can been seen from the data in table 2 the compositions Al to A4 of the present invention containing the quaternary microbiocidal system show a significiant higher microbiocidal activity than the comparative composition B1, which corresponds to presently commercially available compositions for standard CIP in the industry. Even with half of the amount of octanoic acid (A3 and A4) or a third of the amount of N-octenyl succinic acid (A2, A3 and A4) the compositions Al to A4 of the present invention provide the same or better microorganism reduction rates compared to comparative composition BI under identical test conditions. Remarkable is in particular that compositions Al to A4 provided a 99% reduction for A. niger with 4% use solutions, which is the economical upper limit for a use solution while the comparative composition 131 failed.
Table 2 Composition Al A2 A3 A4:,'. 131 softened Water (%) 38.0 41.0 35.0 35.0 15.0 phosphate ester (%) 4.0 4.0 4.0 cumene sulfonate (%) 15.0 15.0 20.0 20.0 30.0 75 %-H3PO4 (%) - - 35.0 - 40.0 53 %-HNO3 (%) 30.0 30.0 - 35.0 -70 %-glycolic acid (%) 5.0 5.0 6.5 6.5 -octanoic acid (%) 2.0 2.0 1.0 1.0 2.0 N-octenyl succinic acid (%) 6.0 3.0 2.5 2.5 9.0 Microbiology minimal use concentration to pass the test A. niger 20 C passed passed passed passed failed 99 % reduction (4%) (4%) (4%) (4%) (4%) min contact time S. diastaticus 20 C passed passed passed passed passed 99.99 % reduction 0.25% 0.5% 1% 10/0 1%
15 min contact time L. brevis 20 C passed passed passed passed passed 99.999 % reduction 0.25% 0.5% 0.5% 0.5% 0.5%
5 min contact time 2. Foaming Evaluation 15 2 litre of a I % use solution was circulated with a flow rate of 1.8 I/s through a temperated 5.5 1 glass cylinder for 30 min to establish a foam/liquid equilibrium. The build-up of foam layer in cm was determined immediately at the end of a 30 min pumping period ("0") and 15 sec after switch off of the pump ("15").
Table 3 Composition Al Al A2 A2 A3 A3 A4 A4 131 BI
time [sec] 0 15 0 15 0 15 0 15 0 15 foam height [cm]
at 10 C 16 15 9 9 <1 0 <1 0 30 30 at 20 C 10 10 6 5 <1 0 <1 0 20 20 at 40 C 0 0 0 0 0 0 0 0 2 1 at 60 C 0 7 0 0 0 0 0 0 0 1 1 The above data clearly show that the quaternary system of the inven-tion leads to signifcant less or no foam, which is necessary for a CIP and/or SIP application compared to composition B1 representing the presently available commercially compositions for standard CIP and SIP applications.
3. Phase Separation (Stability) Test Using the compositions of table 1 0.5%, 1%, 2% and 3% use solutions were prepared as explained above and after conditioning at 20 C for 3 days they were visually inspected for physical instability.
"+" means stability (no phase separation);
will means instability (discernible phase separation).
Composition Al A2 A3 A4 BI
Concentration 0.5% + + + + +
1.0% + + + + -2.0% - + + + -Due to the possibility to reduce the amounts of microbiocidal agents (octanoic acid and N-octenyl succinic acid) the risk of phase separation ac-cording to the present invention is clearly lower. Therefore, higher concen-trated use solutions for CIP and SIP applications are usable without any risk of residues being left behind in the treated plant.
Claims (53)
1. An acidic sanitizing and/or cleaning composition capable of being diluted to form an acidic sanitizing and/or cleaning use solution, the composition comprising:
a) a quaternary antimicrobial system comprising:
.alpha.) at least one C1-C4 hydroxyalkyl carboxylic acid or salt thereof, .beta.) at least one C5-C18 alkyl monocarboxylic acid having the general formula:
R"'- COOH
wherein R"' is a straight or branched, saturated or unsaturated alkyl moiety having 5 to 18 carbon atoms; or salt thereof, .gamma.) at least one substituted dicarboxylic acid having the general formula:
wherein R is a saturated or unsaturated hydrocarbon moiety having
a) a quaternary antimicrobial system comprising:
.alpha.) at least one C1-C4 hydroxyalkyl carboxylic acid or salt thereof, .beta.) at least one C5-C18 alkyl monocarboxylic acid having the general formula:
R"'- COOH
wherein R"' is a straight or branched, saturated or unsaturated alkyl moiety having 5 to 18 carbon atoms; or salt thereof, .gamma.) at least one substituted dicarboxylic acid having the general formula:
wherein R is a saturated or unsaturated hydrocarbon moiety having
2 carbon atoms; R' is an unsubstituted n-alkyl or n-alkenyl moiety having 6 to carbon atoms; n' is an integer of from 1 to 4 and n" is an integer of from 0 to 3;
and R" is hydrogen; or a salt or anhydride thereof;
.delta.) at least one acid capable of yielding a pH of <= 5.0 upon dilution of the composition to a use solution, b) at least one solubilizer;
c) at least one diluent; and d) optionally at least one detergent.
2. The acidic sanitizing and/or cleaning composition of Claim 1 wherein R"' of said at least one C5-C18 alkyl monocarboxylic acid (.beta.), having the general formula: R"'- COOH, is a straight or branched, saturated or unsaturated alkyl moiety having 6 to 12 carbon atoms.
and R" is hydrogen; or a salt or anhydride thereof;
.delta.) at least one acid capable of yielding a pH of <= 5.0 upon dilution of the composition to a use solution, b) at least one solubilizer;
c) at least one diluent; and d) optionally at least one detergent.
2. The acidic sanitizing and/or cleaning composition of Claim 1 wherein R"' of said at least one C5-C18 alkyl monocarboxylic acid (.beta.), having the general formula: R"'- COOH, is a straight or branched, saturated or unsaturated alkyl moiety having 6 to 12 carbon atoms.
3. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2 wherein said at least one C1-C4-hydroxy alkyl carboxylic acid (.alpha.) is an .alpha.-hydroxy alkyl carboxylic acid selected from the group consisting of glycolic acid, lactic acid, hydroxy propanoic acid, dihydroxy propanoic acid, hydroxy butyric acid, and mixtures thereof.
4. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said at least one C5-C18-alkyl monocarboxylic acid (.beta.) is selected from the group consisting of pentanoic acid, hexanoic acid, heptanoic acid, octanoic acid, nonanoic acid, decanoic acid, undecanoic acid, dodecanoic acid, tridecanoic acid, tetradecanoic acid, pentadecanoic acid, hexadecanoic acid heptadecanoic acid, octadecanoic acid, neodecanoic acid, 2,2-dimethyloctanoic acid, and mixtures thereof.
5. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said substituted dicarboxylic acid (.gamma.) is a substituted succinic acid.
6. The acidic sanitizing and/or cleaning composition of Claim 5, wherein said substituted succinic acid is selected from the group consisting of n-octyl succinic acid, n-octenyl succinic acid, n-nonyl succinic acid, n-nonenyl succinic acid, n-decyl succinic acid, n-decenyl succinic acid, n-hexyl succinic acid, n-hexenyl succinic acid, methylheptenyl succinic acid, and mixtures thereof.
7. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said acid (.delta.) is an organic acid.
8. The acidic sanitizing and/or cleaning composition according to Claim 7, wherein said organic acid is selected from the group consisting of formic acid, acetic acid, citric acid, alkyl sulfonic acid, and methyl sulfonic acid.
9. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said acid (.delta.) is an inorganic acid.
10. The acidic sanitizing and/or cleaning composition according to Claim 9, wherein said inorganic acid is selected from the group consisting of phosphoric acid, sulfuric acid, nitric acid, hydrochloric acid, sulfamic acid, methyl sulfonic acid, and mixtures thereof.
11. The acidic sanitizing and/or cleaning composition according to Claim 10, wherein said nitric acid is combined with urea (1 wt.%) to prevent NO x formation.
12. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein the mono- and dicarboxylic acids (.beta., .gamma.) are present in a weight ratio of between 1:1 and 1:20.
13. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein the mono- and dicarboxylic acids (.beta., .gamma.) are present in a weight ratio of between 1:2 and 1:10.
14. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said at least one solubilizer (b) is a surfactant-hydrotrope selected from the group consisting of anionic surfactants, nonionic surfactants, zwitterionic surfactants, and mixtures thereof.
15. The acidic sanitizing and/or cleaning composition according to Claim 14, wherein said anionic surfactant is selected from the group consisting of alkyl sulfonates and alkyl aryl sulfonates in which the alkyl portions contain 8 to 22 carbon atoms, ammonium, alkali metal or alkaline earth metal salts, or mixtures thereof.
16. The acidic sanitizing and/or cleaning composition according to Claim 15, wherein the alkyl portions of said alkyl sulfonates and alkyl aryl sulfonates contain 8 to 18 carbon atoms.
17. The acidic sanitizing and/or cleaning composition according to Claim 14, wherein said anionic surfactant is selected from the group consisting of sodium or potassium alkyl benzene sulfonate, sodium or potassium xylene sulfonate, sodium or potassium cumene sulfonate or sodium or potassium toluene sulfonate.
18. The acidic sanitizing and/or cleaning composition according to Claim 14, wherein the zwitterionic surfactant is selected from the group consisting of alkylimidazolines, alkylamines and mixtures thereof.
19. The acidic sanitizing and/or cleaning composition according to Claim 14, wherein said nonionic surfactant is selected from the group consisting of ethylene oxide adducts of C8 to C22, ethylene oxide/propylene oxide adducts of ethylene glycol, alkylene glycols, or mixtures thereof.
20. The acidic sanitizing and/or cleaning composition according to Claim 19, wherein said ethylene oxide adducts are of C8 to C16.
21. The acidic sanitizing and/or cleaning composition according to Claim 19, wherein said ethylene oxide adducts are of C8 to C12 alcohols.
22. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said at least one diluent is selected from water and short chain alcohols having 2 to 5 carbon atoms.
23. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said at least one diluent is potable drinking water.
24. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said C1-C4-hydroxyalkyl carboxylic acid (.alpha.) is present in an amount of from 0.25 to 15 wt.%, based on the total amount of the composition.
25. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said C1-C4-hydroxyalkyl carboxylic acid (.alpha.) is present in an amount of from 1 to 10 wt.%, based on the total amount of the composition.
26. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said C1-C4-hydroxyalkyl carboxylic acid (.alpha.) is present in an amount of from 2 to 8 wt.%, based on the total amount of the composition.
27. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said C1-C4-hydroxyalkyl carboxylic acid (.alpha.) is present in an amount of from 3 to 8 wt.%, based on the total amount of the composition.
28. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said C5-C18 alkyl monocarboxylic acid (.beta.) is present in an amount of from 0.1 to 5 wt.%, based on the total amount of the composition.
29. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said C5-C18 alkyl monocarboxylic acid (.beta.) is present in an amount of from 0.3 to 4 wt.%, based on the total amount of the composition.
30. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said C5-C18 alkyl monocarboxylic acid (.beta.) is present in an amount of from 0.5 to 2.0 wt.%, based on the total amount of the composition.
31. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said dicarboxylic acid (.gamma.) is present in an amount of from 0.1 to 8 wt.%, based on the total amount of the composition.
32. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said dicarboxylic acid (.gamma.) is present in an amount of from 0.5 to 6 wt.%, based on the total amount of the composition.
33. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said dicarboxylic acid (.gamma.) is present in an amount of from 1 to 4.5 wt.%, based on the total amount of the composition.
34. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said acid (.delta.) is present in an amount of from 4.0 to 60.0 wt.%, based on the total amount of the composition.
35. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said acid (.delta.) is present in an amount of from 10 to 40 wt.%, based on the total amount of the composition.
36. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said diluent (c) is present in an amount of from 10 to 95.5 wt.%, based on the total amount of the composition.
37. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said diluent (c) is present in an amount of from 15 to wt.%, based on the total amount of the composition.
38. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said detergent (d) is present in an amount of from 5 to wt.%, based on the total weight of the composition.
39. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said detergent (d) is present in an amount of from 10 to wt.%, based on the total weight of the composition.
40. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said composition is diluted with water in a ratio of from 1:10 to 1:500 parts of composition to water.
41. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said composition is diluted with water in a ratio of from 1:30 to 1:400 parts of composition to water.
42. The acidic sanitizing and/or cleaning composition according to Claim 1 or 2, wherein said composition is diluted with water in a ratio of from 1:50 to 1:100 parts of composition to water.
43. The composition according to any one of Claims 40 to 42, wherein said composition is in the form of a low foaming acidic sanitizing and/or cleaning use solution.
44. The low foaming acidic aqueous antimicrobial sanitizing and/or cleaning use solution according to Claim 43, wherein said use solution comprises:
a) from 1 to 5000 ppm of the acids (.alpha.), (.beta.) and (.gamma.) of the antimicrobial system (a);
b) from 5 to 10 000 ppm of the solubilizer (b), and c) a sufficient amount of the acid (.delta.) of the antimicrobial system (a) to yield a pH below 5.0, d) optionally a sufficient amount of the detergent (d) to induce surface wetting and soil removal and e) water as the balance of the composition.
a) from 1 to 5000 ppm of the acids (.alpha.), (.beta.) and (.gamma.) of the antimicrobial system (a);
b) from 5 to 10 000 ppm of the solubilizer (b), and c) a sufficient amount of the acid (.delta.) of the antimicrobial system (a) to yield a pH below 5.0, d) optionally a sufficient amount of the detergent (d) to induce surface wetting and soil removal and e) water as the balance of the composition.
45. The low foaming acidic aqueous antimicrobial sanitizing and/or cleaning use solution according to Claim 44, wherein said use solution comprises from 5 to 3000 ppm of the acids (.alpha.), (.beta.) and (.gamma.) of the antimicrobial system (a).
46. The low foaming acidic aqueous antimicrobial sanitizing and/or cleaning use solution according to Claim 44, wherein said use solution comprises from 10 to 1500 ppm of the acids (.alpha.), (.beta.) and (.gamma.) of the antimicrobial system (a).
47. The low foaming acidic aqueous antimicrobial sanitizing and/or cleaning use solution according to any one of Claims 44 to 46, wherein said use solution comprises from 10 to 5000 ppm of the solubilizer (b).
48. The low foaming acidic aqueous antimicrobial sanitizing and/or cleaning use solution according to any one of Claims 44 to 47, wherein said use solution comprises a sufficient amount of the acid (.delta.) of the antimicrobial system (a) to yield a pH from 4.5 to 1Ø
49. A process for sanitizing and/or cleaning a hard surface, the process being carried out by contacting the low foaming acidic aqueous antimicrobial sanitizing and/or cleaning use solution of any one of claims 43 to 48 at a temperature of from 0 to 80 °C, with the hard surface to be cleaned and/or sanitized for 30 s to 20 min, draining off the use solution, and finally rinsing the hard surface with potable water.
50. The process for sanitizing and/or cleaning the hard surface of Claim 49, wherein said process is carried out at a temperature of from 5 to 60 °C.
51. The process for sanitizing and/or cleaning the hard surface of Claim 49 or 50, wherein said hard surface is to be cleaned and/or sanitized for 1 to min.
52. The process for sanitizing and/or cleaning the hard surface of any one of Claims 49 to 51, wherein said process is a cleaning-in-place and/or sanitize-in-place process for cleaning and/or sanitizing plants in the food, dairy, beverage, brewery and soft drink industries.
53. The process for sanitizing and/or cleaning the hard surface of any one of Claims 49 to 52, wherein said use solution is recycled after draining.
Applications Claiming Priority (3)
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| EP04001840A EP1561801A1 (en) | 2004-01-28 | 2004-01-28 | Sanitizing and cleaning composition and its use for sanitizing and/or cleaning hard surfaces |
| EP04001840.0 | 2004-01-28 | ||
| PCT/US2005/002424 WO2005073359A1 (en) | 2004-01-28 | 2005-01-26 | Sanitizing and cleaning composition and its use for sanitizing and/or cleaning hard surfaces |
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| EP (2) | EP1561801A1 (en) |
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| US6855328B2 (en) * | 2002-03-28 | 2005-02-15 | Ecolab Inc. | Antimicrobial and antiviral compositions containing an oxidizing species |
| EP1561801A1 (en) * | 2004-01-28 | 2005-08-10 | JohnsonDiversey Inc. | Sanitizing and cleaning composition and its use for sanitizing and/or cleaning hard surfaces |
| WO2008015381A1 (en) * | 2006-07-31 | 2008-02-07 | Reckitt Benckiser (Uk) Limited | Improved hard surface cleaning compositions |
-
2004
- 2004-01-28 EP EP04001840A patent/EP1561801A1/en not_active Withdrawn
-
2005
- 2005-01-26 CA CA2554746A patent/CA2554746C/en active Active
- 2005-01-26 EP EP05722545A patent/EP1709145B1/en active Active
- 2005-01-26 KR KR1020067017214A patent/KR101153629B1/en active IP Right Grant
- 2005-01-26 WO PCT/US2005/002424 patent/WO2005073359A1/en active Application Filing
- 2005-01-26 US US10/589,384 patent/US7943565B2/en active Active
- 2005-01-26 AT AT05722545T patent/ATE434032T1/en not_active IP Right Cessation
- 2005-01-26 BR BRPI0507251A patent/BRPI0507251B1/en active IP Right Grant
- 2005-01-26 AU AU2005207949A patent/AU2005207949B2/en active Active
- 2005-01-26 ES ES05722545T patent/ES2344012T3/en active Active
- 2005-01-26 DE DE602005014937T patent/DE602005014937D1/en active Active
- 2005-01-26 JP JP2006551426A patent/JP4966020B2/en active Active
- 2005-01-26 CN CNB2005800055200A patent/CN100475941C/en active Active
-
2011
- 2011-04-08 US US13/082,991 patent/US8188025B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005207949A1 (en) | 2005-08-11 |
| JP2007522132A (en) | 2007-08-09 |
| JP4966020B2 (en) | 2012-07-04 |
| CA2554746A1 (en) | 2005-08-11 |
| AU2005207949B2 (en) | 2010-08-26 |
| EP1709145A1 (en) | 2006-10-11 |
| US20080319070A1 (en) | 2008-12-25 |
| US8188025B2 (en) | 2012-05-29 |
| WO2005073359A1 (en) | 2005-08-11 |
| KR101153629B1 (en) | 2012-06-18 |
| EP1709145B1 (en) | 2009-06-17 |
| BRPI0507251B1 (en) | 2016-03-08 |
| CN100475941C (en) | 2009-04-08 |
| ES2344012T3 (en) | 2010-08-16 |
| ATE434032T1 (en) | 2009-07-15 |
| BRPI0507251A (en) | 2007-06-26 |
| US20110182771A1 (en) | 2011-07-28 |
| KR20070003877A (en) | 2007-01-05 |
| EP1561801A1 (en) | 2005-08-10 |
| CN1922297A (en) | 2007-02-28 |
| DE602005014937D1 (en) | 2009-07-30 |
| US7943565B2 (en) | 2011-05-17 |
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