CA2508198A1 - Orifice device having multiple channels and multiple layers for drug delivery - Google Patents

Orifice device having multiple channels and multiple layers for drug delivery Download PDF

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Publication number
CA2508198A1
CA2508198A1 CA002508198A CA2508198A CA2508198A1 CA 2508198 A1 CA2508198 A1 CA 2508198A1 CA 002508198 A CA002508198 A CA 002508198A CA 2508198 A CA2508198 A CA 2508198A CA 2508198 A1 CA2508198 A1 CA 2508198A1
Authority
CA
Canada
Prior art keywords
orifice device
windings
separate channels
inner member
orifice
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002508198A
Other languages
French (fr)
Other versions
CA2508198C (en
Inventor
Scott M. Russell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cordis Corp
Original Assignee
Cordis Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cordis Corp filed Critical Cordis Corp
Publication of CA2508198A1 publication Critical patent/CA2508198A1/en
Application granted granted Critical
Publication of CA2508198C publication Critical patent/CA2508198C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16877—Adjusting flow; Devices for setting a flow rate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K1/00—Lift valves or globe valves, i.e. cut-off apparatus with closure members having at least a component of their opening and closing motion perpendicular to the closing faces
    • F16K1/32—Details
    • F16K1/34—Cutting-off parts, e.g. valve members, seats
    • F16K1/36—Valve members
    • F16K1/40—Valve members of helical shape
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K47/00—Means in valves for absorbing fluid energy
    • F16K47/08—Means in valves for absorbing fluid energy for decreasing pressure or noise level and having a throttling member separate from the closure member, e.g. screens, slots, labyrinths
    • F16K47/12—Means in valves for absorbing fluid energy for decreasing pressure or noise level and having a throttling member separate from the closure member, e.g. screens, slots, labyrinths the throttling channel being of helical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M2005/14513—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons with secondary fluid driving or regulating the infusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1407—Infusion of two or more substances
    • A61M5/1408—Infusion of two or more substances in parallel, e.g. manifolds, sequencing valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804—Flow controllers

Abstract

An orifice device for delivering one or more drugs includes an inner member having a proximal end and a distal end; and a plurality of windings helically wound around the inner member. Each winding defines a separate layer and each winding includes at least one wire helically wound around the inner member.
The plurality of windings and the inner member define at least two separate channels for carrying one or more drugs therethrough. An inlet is at the proximal end of each of the plurality of windings and an outlet is at the distal end of the plurality of windings. At least one of the plurality of windings has a plurality of distinct wires helically wound in parallel around the inner member and at least one of the plurality of windings respectively. In some embodiments, the plurality of windings and the inner member define at least three separate channels for carrying one or more drugs therethrough. In some embodiments, at least two of the plurality of distinct wires have a different dimension. Additionally, an outer member is used over the plurality of windings. In some embodiments, at least one of the at least two separate channels has a different fluid flow rate. And, in other embodiments, at least two of the at least three separate channels have a different fluid flow rate. In some embodiments, at least one of the at least two separate channels carry a different drug.

Claims (30)

1. An orifice device for delivering one or more drugs comprising:
an inner member having a proximal end and a distal end;
a plurality of windings helically wound around the inner member, each winding defining a separate layer, each winding comprising at least one wire helically wound around the inner member;
the plurality of windings and the inner member defining at least two separate channels for carrying one or more drugs therethrough and an inlet at the proximal end of each of the plurality of windings and an outlet at the distal end of the plurality of windings.
2. The orifice device according to Claim 1, wherein at least one of the plurality of windings has a plurality of distinct wires helically wound in parallel around the inner member and at least one of the plurality of windings respectively.
3. The orifice device according to Claim 1, wherein the plurality of windings and the inner member defining at least three separate channels for carrying one or more drugs therethrough
4. The orifice device according to Claim 3, wherein at least two of the plurality of distinct wires have a different dimension.
5. The orifice device according to Claim 1, further comprising an outer member over the plurality of windings.
6. The orifice device according to Claim 1, wherein at least one of the at least two separate channels has a different fluid flow rate.
7. The orifice device according to Claim 3, wherein at least two of the at least three separate channels have a different fluid flow rate.
8. The orifice device according to Claim 1, wherein at least one of the at least two separate channels carry a different drug.
9. The orifice device according to Claim 3, wherein at least two of the at least three separate channels carry a different drug.
10. The orifice device according to Claim 5, wherein the outer member comprises channel filling material for blocking drug flow through one of the at least two separate channels.
11. The orifice device according to Claim 2, wherein at least one of the plurality of distinct wires has a circular shape in cross-section.
12. The orifice device according to Claim 2, wherein at least one of the plurality of distinct wires has a hexagonal shape in cross-section.
13. The orifice device according to Claim 2, wherein at least one of the plurality of distinct wires has an octagonal shape in cross-section.
14. The orifice device according to Claim 2, wherein at least one of the plurality of distinct wires has a triangular shape in cross-section.
15. The orifice device according to Claim 5, further comprising an outer member between at least one of the plurality of windings.
16. The orifice device according to Claim 15, wherein at least one of the outer members is a sleeve.
17. The orifice device according to Claim 15, wherein at least one of the outer members is made of a polymer material.
18. The orifice device according to Claim 12, wherein the polymer material is PTFE.
19. The orifice device according to Claim10, wherein the channel filling material is a glue.
20. The orifice device according to Claim 2, wherein the plurality of distinct wires are made of a degradation-resistant material.
21. The orifice device according to Claim 20, wherein the material is a nickel titanium alloy.
22. The orifice device according to Claim 20, wherein the material is a stainless steel alloy.
23. The orifice device according to Claim 20, wherein the material is plastic.
24. The orifice device according to Claim 1, wherein the plurality of distinct wires each have a width ranging from .001 - .050 inches.
25. The orifice device according to Claim 24, wherein the plurality of distinct wires each have a width ranging from .004 - .005 inches.
26. The orifice device according to Claim 15, wherein the wherein the plurality of windings and the inner member define four separate channels for carrying one or more drugs therethrough.
27. The orifice device according to Claim 26, wherein at least one of the four separate channels has a different fluid flow rate.
28. The orifice device according to Claim 26, wherein at least one of the four separate channels carries a different drug therethrough.
29. The orifice device according to Claim 26, wherein each of the four separate channels has a different fluid flow rate.
30. The orifice device according to Claim 29, wherein each of the four separate channels carries a different drug therethrough.
CA2508198A 2004-05-27 2005-05-25 Orifice device having multiple channels and multiple layers for drug delivery Expired - Fee Related CA2508198C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/855,141 2004-05-27
US10/855,141 US8109922B2 (en) 2003-06-12 2004-05-27 Orifice device having multiple channels and multiple layers for drug delivery

Publications (2)

Publication Number Publication Date
CA2508198A1 true CA2508198A1 (en) 2005-11-27
CA2508198C CA2508198C (en) 2012-07-31

Family

ID=34993178

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2508198A Expired - Fee Related CA2508198C (en) 2004-05-27 2005-05-25 Orifice device having multiple channels and multiple layers for drug delivery

Country Status (14)

Country Link
US (1) US8109922B2 (en)
EP (1) EP1600188B1 (en)
JP (1) JP4954500B2 (en)
KR (1) KR20060046186A (en)
AT (1) ATE385426T1 (en)
AU (1) AU2005201875B2 (en)
CA (1) CA2508198C (en)
DE (1) DE602005004629T2 (en)
DK (1) DK1600188T3 (en)
ES (1) ES2299968T3 (en)
HK (1) HK1085412A1 (en)
IL (1) IL168362A (en)
PL (1) PL1600188T3 (en)
PT (1) PT1600188E (en)

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US8491571B2 (en) * 2003-06-12 2013-07-23 Cordis Corporation Orifice device having multiple channels with varying flow rates for drug delivery
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Also Published As

Publication number Publication date
EP1600188B1 (en) 2008-02-06
JP4954500B2 (en) 2012-06-13
ES2299968T3 (en) 2008-06-01
PT1600188E (en) 2008-03-18
IL168362A (en) 2012-10-31
ATE385426T1 (en) 2008-02-15
DE602005004629D1 (en) 2008-03-20
DE602005004629T2 (en) 2009-01-29
PL1600188T3 (en) 2008-07-31
EP1600188A3 (en) 2005-12-07
CA2508198C (en) 2012-07-31
KR20060046186A (en) 2006-05-17
US20040267241A1 (en) 2004-12-30
AU2005201875A1 (en) 2005-12-15
DK1600188T3 (en) 2008-06-09
JP2005334652A (en) 2005-12-08
US8109922B2 (en) 2012-02-07
EP1600188A2 (en) 2005-11-30
AU2005201875B2 (en) 2011-02-03
HK1085412A1 (en) 2006-08-25

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Effective date: 20190527