CA2496576A1 - Medical devices and methods of making the same - Google Patents

Medical devices and methods of making the same Download PDF

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Publication number
CA2496576A1
CA2496576A1 CA002496576A CA2496576A CA2496576A1 CA 2496576 A1 CA2496576 A1 CA 2496576A1 CA 002496576 A CA002496576 A CA 002496576A CA 2496576 A CA2496576 A CA 2496576A CA 2496576 A1 CA2496576 A1 CA 2496576A1
Authority
CA
Canada
Prior art keywords
endoprosthesis
fibers
tubular member
polymer
oriented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002496576A
Other languages
French (fr)
Other versions
CA2496576C (en
Inventor
Jonathan S. Stinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Scientific Ltd Bermuda
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2496576A1 publication Critical patent/CA2496576A1/en
Application granted granted Critical
Publication of CA2496576C publication Critical patent/CA2496576C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/88—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/89—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A61F2002/075—Stent-grafts the stent being loosely attached to the graft material, e.g. by stitching
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
    • A61F2250/0098—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24058—Structurally defined web or sheet [e.g., overall dimension, etc.] including grain, strips, or filamentary elements in respective layers or components in angular relation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24058—Structurally defined web or sheet [e.g., overall dimension, etc.] including grain, strips, or filamentary elements in respective layers or components in angular relation
    • Y10T428/24074—Strand or strand-portions
    • Y10T428/24091—Strand or strand-portions with additional layer[s]
    • Y10T428/24099—On each side of strands or strand-portions
    • Y10T428/24107—On each side of strands or strand-portions including mechanically interengaged strands, strand-portions or strand-like strips

Abstract

Medical devices, for example, implantable devices such as endoprostheses, include a composite material having a polymer.

Claims (32)

1. An endoprosthesis, comprising:
a tubular member including a polymer matrix and a plurality of fibers in the matrix, the fibers having a stiffness greater than the stiffness of the polymer and being substantially oriented in a predetermined direction.
2. The endoprosthesis of claim 1, wherein the fibers are oriented substantially circumferentially relative to a longitudinal axis of the tubular member.
3. The endoprosthesis of claim 1, wherein the fibers are oriented substantially longitudinally relative to the tubular member.
4. The endoprosthesis of claim 1, wherein the fibers are oriented substantially radially relative to the tubular member.
5. The endoprosthesis of claim 1, wherein the fibers comprise a metal.
6. The endoprosthesis of claim 1, wherein the fibers comprise a polymer.
7. The endoprosthesis of claim 1, wherein the fibers are dispersed throughout substantially the entire matrix.
8. The endoprosthesis of claim 1, wherein the fibers are formed on preselected portions of the tubular member.
9. The endoprosthesis of claim 1, wherein the fibers extend helically around the tubular member.
10. The endoprosthesis of claim 1, wherein the fibers are formed in a configuration that enhances the radial strength of the tubular member.
11. The endoprosthesis of claim 1, wherein the fibers are formed in a configuration that enhances the hoop strength of the tubular member.
12. The endoprosthesis of claim 1, wherein the fibers have a first end that is larger than a second end.
13. The endoprosthesis of claim 1, wherein the fibers are formed of a material selected from the group of gold, tantalum, platinum, and tungsten.
14. The endoprosthesis of claim 1, wherein the fibers are visible by magnetic resonance imaging.
15. The endoprosthesis of claim 1, wherein the fibers are invisible by magnetic resonance imaging.
16. The endoprosthesis of claim 1, further comprising a magnetopaque material different than the fibers in the matrix.
17. The endoprosthesis of claim 1, wherein the tubular member is formed of a plurality of polymeric layers.
18. The endoprosthesis of claim 17, wherein the plurality of polymeric layers includes a layer having fibers oriented substantially longitudinally relative to the tubular member, and a layer having fibers oriented substantially radially relative to the tubular member.
19. The endoprosthesis of claim 1, further comprising a drug-releasing layer on the tubular member.
20. The endoprosthesis of claim 1, wherein the matrix comprises a drug.
21. The endoprosthesis of claim 1, in the form of a balloon-expandable stent.
22. An endoprosthesis, comprising:
a tubular member comprising a polymer; and a first member extending helically around the tubular member, the first member having a stiffness greater than stiffness of the polymer.
23. The endoprosthesis of claim 22, wherein the first member comprises a metal.
24. The endoprosthesis of claim 22, wherein the first member comprises a polymer.
25. The endoprosthesis of claim 22, wherein the tubular member comprises a plurality of fibers in the polymer, the fibers having a stiffness greater than the stiffness of the polymer and being substantially oriented in a predetermined direction.
26. The endoprosthesis of claim 22, wherein the polymer encapsulates the first member.
27. An endoprosthesis, comprising:
a tubular member having a first layer including a first polymer; and a second layer including a second polymer and a plurality of fibers in the second polymer, the fibers having a stiffness greater than the stiffness of the polymer and being oriented in a predetermined direction.
28. The endoprosthesis of claim 27, wherein the first layer further includes a plurality of fibers oriented in a predetermined direction.
29. The endoprosthesis of claim 28, wherein the pluralities of fibers in the first and second layers are substantially the same.
30. The endoprosthesis of claim 28, wherein the pluralities of fibers in the first and second layers are oriented in different directions.
31. The endoprosthesis of claim 28, wherein the pluralities of fibers in the first and second layers are oriented in the same direction.
32. The endoprosthesis of claim 27, wherein the first and second polymers are the same polymer.
CA2496576A 2002-08-28 2003-08-05 Medical devices and methods of making the same Expired - Fee Related CA2496576C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/229,548 2002-08-28
US10/229,548 US7029495B2 (en) 2002-08-28 2002-08-28 Medical devices and methods of making the same
PCT/US2003/024302 WO2004019821A1 (en) 2002-08-28 2003-08-05 Medical devices and methods of making the same

Publications (2)

Publication Number Publication Date
CA2496576A1 true CA2496576A1 (en) 2004-03-11
CA2496576C CA2496576C (en) 2010-11-30

Family

ID=31976250

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2496576A Expired - Fee Related CA2496576C (en) 2002-08-28 2003-08-05 Medical devices and methods of making the same

Country Status (6)

Country Link
US (2) US7029495B2 (en)
EP (1) EP1545394B1 (en)
JP (1) JP2005537090A (en)
AU (1) AU2003261349B2 (en)
CA (1) CA2496576C (en)
WO (1) WO2004019821A1 (en)

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