CA2485721A1 - Drug delivery device and method for vaporization - Google Patents
Drug delivery device and method for vaporization Download PDFInfo
- Publication number
- CA2485721A1 CA2485721A1 CA002485721A CA2485721A CA2485721A1 CA 2485721 A1 CA2485721 A1 CA 2485721A1 CA 002485721 A CA002485721 A CA 002485721A CA 2485721 A CA2485721 A CA 2485721A CA 2485721 A1 CA2485721 A1 CA 2485721A1
- Authority
- CA
- Canada
- Prior art keywords
- substrate
- drug
- combustible
- combustible element
- interior
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/06—Inhaling appliances shaped like cigars, cigarettes or pipes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F42/00—Simulated smoking devices other than electrically operated; Component parts thereof; Manufacture or testing thereof
- A24F42/60—Constructional details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
- A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
- A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
- A61M11/042—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters electrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
- A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
- A61M11/047—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters by exothermic chemical reaction
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24V—COLLECTION, PRODUCTION OR USE OF HEAT NOT OTHERWISE PROVIDED FOR
- F24V30/00—Apparatus or devices using heat produced by exothermal chemical reactions other than combustion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8268—Fuel storage cells
Abstract
Disclosed is a method and device for rapid heating of a coated substance which preferably includes a drug to vaporize for inhalation therapy. A device (10) in accordance with the present invention preferably includes a substrate (20) which has an interior surface (20a) surrounding an interior region and an exterior surface (20b) upon which the coated substance (15) is to be adhered.
Though the substrate is preferably metallic, it does not need to be. A
combustible element (16a.16b) is placed in the interior region of the substrate and a spark or resistance igniter is connected to the combustible element. The igniter is for initiating oxidation of the combustible element.
Preferably, the coated substance is vaporized inside of a housing (30) to allow the vaporized drug to aerosolize and be inhaled by a user.
Though the substrate is preferably metallic, it does not need to be. A
combustible element (16a.16b) is placed in the interior region of the substrate and a spark or resistance igniter is connected to the combustible element. The igniter is for initiating oxidation of the combustible element.
Preferably, the coated substance is vaporized inside of a housing (30) to allow the vaporized drug to aerosolize and be inhaled by a user.
Claims (36)
1. A device for rapid heating and vaporization of a coated drug substance including:
a substrate having an interior surface surrounding an interior region, for completely containing a combustible element and products of a combustion reaction, and an exterior surface;
a combustible element sealed inside the interior region of the substrate;
a spark or resistance igniter connected to the combustible element for initiating oxidation of the combustible element; and a drug coating on the exterior surface of the substrate, which contains a drug that is vaporized upon ignition of the combustion element.
a substrate having an interior surface surrounding an interior region, for completely containing a combustible element and products of a combustion reaction, and an exterior surface;
a combustible element sealed inside the interior region of the substrate;
a spark or resistance igniter connected to the combustible element for initiating oxidation of the combustible element; and a drug coating on the exterior surface of the substrate, which contains a drug that is vaporized upon ignition of the combustion element.
2. The device of Claim 1, wherein the combustible element is sealed in a bulb.
3. The device of Claim 2, wherein the bulb is formed from glass.
4. The device of Claim 3, wherein the bulb constitutes the interior and exterior surfaces of the substrate.
5. The device of Claim 1, wherein the substrate is metallic.
6. The device of Claim 5, wherein the substrate is formed from stainless steel or aluminum.
7. The device of Claim 1, wherein the interior surface of the substrate is light absorbing.
8. The device of Claim 3, wherein the substrate includes a sheath surrounding the glass bulb or a polymer coating.
9. The device of Claim 1, wherein the combustible element consumes gas upon combustion.
19 The device of Claim 9, wherein the combustible element includes a combustible metal.
11. The device of Claim 10, wherein the combustible element includes magnesium, zirconium or aluminum.
12. The device of Claim 2, wherein the substrate is coated onto the sealed bulb.
13. The device of Claim 1, that further includes a housing around the exterior surface of the substrate to facilitate inhalation of the drug after vaporization thereof.
14. The device of Claim 13, wherein the housing includes a mouthpiece to facilitate oral inhalation of the drug after vaporization thereof.
15. The device of Claim 13, wherein the housing includes a nasal attachment to facilitate nasal inhalation of the drug after vaporization thereof.
16. A device for vaporizing a drug including:
a substrate having an interior surface surrounding an interior region and an exterior surface;
a combustible element contained inside the interior region of the substrate;
a spark or resistance igniter connected to the combustible element and for initiating combustion of the combustible element; and a drug adhered to the exterior surface of the substrate, the drug to be vaporized upon ignition of the combustible element.
a substrate having an interior surface surrounding an interior region and an exterior surface;
a combustible element contained inside the interior region of the substrate;
a spark or resistance igniter connected to the combustible element and for initiating combustion of the combustible element; and a drug adhered to the exterior surface of the substrate, the drug to be vaporized upon ignition of the combustible element.
17. The device of Claim 16, wherein the combustible element is contained inside a sealed bulb.
18. The device of Claim 16, wherein the substrate is metallic.
19. The device of Claim 17, wherein the bulb is formed from glass.
20. The device of Claim 17, wherein the bulb constitutes the interior and exterior surfaces of the substrate.
21. The device of Claim 18, wherein the substrate is formed from stainless steel or aluminum.
22. The device of Claim 21, wherein the interior surface of the substrate is anodized.
23. The device of Claim 17, wherein the substrate includes a sheath surrounding the bulb or a polymer coating.
24. The device of Claim 16, wherein the combustible element consumes gas upon combustion.
25. The device of Claim 16, wherein the combustible element includes a combustible metal.
26. The device of Claim 25, wherein the combustible element includes magnesium, zirconium or aluminum.
27. The device of Claim 16 that further includes a housing enclosing the exterior surface of the substrate to facilitate inhalation of the drug after vaporization thereof.
28. The device of Claim 27, wherein the housing includes a mouthpiece to facilitate oral inhalation of the drug after vaporization thereof.
29. The device of Claim 28, wherein the igniter includes a power source for ignition of the substrate and wherein the device is separable into two sections, a first section housing the power source and the second section housing the substrate, combustible element and drug.
30. A method for aerosolizing a drug including:
providing a substrate having an interior surface surrounding an interior region and an exterior surface;
coating the exterior surface of the substrate with at least one drug;
locating a combustible filament in the interior region of the substrate; and igniting the combustible filament via spark or resistance heating in the interior region to heat the exterior surface of the substrate and vaporize the drug coated thereon.
providing a substrate having an interior surface surrounding an interior region and an exterior surface;
coating the exterior surface of the substrate with at least one drug;
locating a combustible filament in the interior region of the substrate; and igniting the combustible filament via spark or resistance heating in the interior region to heat the exterior surface of the substrate and vaporize the drug coated thereon.
31. The method of Claim 30, wherein locating the combustible filament in the interior region of the substrate includes enclosing the combustible filament in a sealed bulb and locating the sealed bulb in the interior region of the substrate.
32. The method of Claim 31, wherein providing a substrate includes forming the substrate from stainless steel or aluminum.
33. The method of Claim 32, wherein providing a substrate includes anodizing the interior surface of the substrate.
34. The method of Claim 33, wherein locating the combustible filament in the interior region of the substrate includes providing a combustible filament including magnesium, zirconium or aluminum.
35. The method of Claim 31 that further comprises enclosing the substrate within a housing that facilitates aerosolization of the drug after vaporization thereof.
36. A device for vaporizing a drug including:
a substrate having a surface surrounding an interior area;
a combustible element placed in the interior area of the substrate;
an igniter connected to the combustible element and for initiating combustion of the combustible element; and a drug absorbed into the substrate, the drug to be vaporized upon ignition of the combustible element.
a substrate having a surface surrounding an interior area;
a combustible element placed in the interior area of the substrate;
an igniter connected to the combustible element and for initiating combustion of the combustible element; and a drug absorbed into the substrate, the drug to be vaporized upon ignition of the combustible element.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/146,086 US7458374B2 (en) | 2002-05-13 | 2002-05-13 | Method and apparatus for vaporizing a compound |
US10/146,086 | 2002-05-13 | ||
PCT/US2003/014983 WO2003095012A1 (en) | 2002-05-13 | 2003-05-13 | Method and apparatus for vaporizing a compound |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2485721A1 true CA2485721A1 (en) | 2003-11-20 |
CA2485721C CA2485721C (en) | 2011-07-26 |
Family
ID=29400465
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2485721A Expired - Fee Related CA2485721C (en) | 2002-05-13 | 2003-05-13 | Drug delivery device and method for vaporization |
Country Status (16)
Country | Link |
---|---|
US (2) | US7458374B2 (en) |
EP (3) | EP3207954A1 (en) |
JP (1) | JP4426439B2 (en) |
CN (2) | CN101623528B (en) |
AT (1) | ATE425784T1 (en) |
CA (1) | CA2485721C (en) |
CY (1) | CY1118820T1 (en) |
DE (1) | DE60326713D1 (en) |
DK (1) | DK2052753T3 (en) |
ES (2) | ES2623467T3 (en) |
HK (3) | HK1081888A1 (en) |
IL (1) | IL165161A0 (en) |
MX (1) | MXPA04011279A (en) |
PT (1) | PT2052753T (en) |
SI (1) | SI2052753T1 (en) |
WO (1) | WO2003095012A1 (en) |
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2002
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- 2003-05-13 ES ES09002094.2T patent/ES2623467T3/en not_active Expired - Lifetime
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- 2003-05-13 EP EP16204982.9A patent/EP3207954A1/en not_active Withdrawn
- 2003-05-13 CN CN2009101667825A patent/CN101623528B/en not_active Expired - Fee Related
- 2003-05-13 PT PT90020942T patent/PT2052753T/en unknown
- 2003-05-13 WO PCT/US2003/014983 patent/WO2003095012A1/en active Application Filing
- 2003-05-13 ES ES03734014T patent/ES2323418T3/en not_active Expired - Lifetime
- 2003-05-13 DK DK09002094.2T patent/DK2052753T3/en active
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CN101623528B (en) | 2012-03-07 |
CA2485721C (en) | 2011-07-26 |
WO2003095012B1 (en) | 2004-03-04 |
PT2052753T (en) | 2017-04-11 |
EP1506031A1 (en) | 2005-02-16 |
CN1662272A (en) | 2005-08-31 |
JP2005525178A (en) | 2005-08-25 |
SI2052753T1 (en) | 2017-05-31 |
US7458374B2 (en) | 2008-12-02 |
EP2052753B1 (en) | 2017-01-25 |
ES2323418T3 (en) | 2009-07-15 |
DE60326713D1 (en) | 2009-04-30 |
CY1118820T1 (en) | 2018-01-10 |
IL165161A0 (en) | 2005-12-18 |
CN101623528A (en) | 2010-01-13 |
EP3207954A1 (en) | 2017-08-23 |
EP1506031B1 (en) | 2009-03-18 |
HK1129077A1 (en) | 2009-11-20 |
ES2623467T3 (en) | 2017-07-11 |
AU2003239441A1 (en) | 2003-11-11 |
US20030209240A1 (en) | 2003-11-13 |
HK1243014A1 (en) | 2018-07-06 |
WO2003095012A1 (en) | 2003-11-20 |
ATE425784T1 (en) | 2009-04-15 |
DK2052753T3 (en) | 2017-04-24 |
HK1081888A1 (en) | 2006-05-26 |
US7987846B2 (en) | 2011-08-02 |
CN100540080C (en) | 2009-09-16 |
US20090071477A1 (en) | 2009-03-19 |
EP2052753A1 (en) | 2009-04-29 |
JP4426439B2 (en) | 2010-03-03 |
MXPA04011279A (en) | 2005-02-17 |
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