CA2485069A1 - Stent coating device - Google Patents

Stent coating device Download PDF

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Publication number
CA2485069A1
CA2485069A1 CA002485069A CA2485069A CA2485069A1 CA 2485069 A1 CA2485069 A1 CA 2485069A1 CA 002485069 A CA002485069 A CA 002485069A CA 2485069 A CA2485069 A CA 2485069A CA 2485069 A1 CA2485069 A1 CA 2485069A1
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CA
Canada
Prior art keywords
coating
applicator
coating device
type
fluid delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002485069A
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French (fr)
Other versions
CA2485069C (en
Inventor
Avraham Shekalim
Ascher Shmulewitz
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Labcoat Ltd
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Individual
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Filing date
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Application filed by Individual filed Critical Individual
Publication of CA2485069A1 publication Critical patent/CA2485069A1/en
Application granted granted Critical
Publication of CA2485069C publication Critical patent/CA2485069C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B12/00—Arrangements for controlling delivery; Arrangements for controlling the spray area
    • B05B12/08—Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means
    • B05B12/12—Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means responsive to conditions of ambient medium or target, e.g. humidity, temperature position or movement of the target relative to the spray apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B13/00—Machines or plants for applying liquids or other fluent materials to surfaces of objects or other work by spraying, not covered by groups B05B1/00 - B05B11/00
    • B05B13/02—Means for supporting work; Arrangement or mounting of spray heads; Adaptation or arrangement of means for feeding work
    • B05B13/04—Means for supporting work; Arrangement or mounting of spray heads; Adaptation or arrangement of means for feeding work the spray heads being moved during spraying operation
    • B05B13/0442—Installation or apparatus for applying liquid or other fluent material to separate articles rotated during spraying operation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C5/00—Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work
    • B05C5/02—Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work the liquid or other fluent material being discharged through an outlet orifice by pressure, e.g. from an outlet device in contact or almost in contact, with the work
    • B05C5/0208—Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work the liquid or other fluent material being discharged through an outlet orifice by pressure, e.g. from an outlet device in contact or almost in contact, with the work for applying liquid or other fluent material to separate articles
    • B05C5/0212—Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work the liquid or other fluent material being discharged through an outlet orifice by pressure, e.g. from an outlet device in contact or almost in contact, with the work for applying liquid or other fluent material to separate articles only at particular parts of the articles
    • B05C5/0216—Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work the liquid or other fluent material being discharged through an outlet orifice by pressure, e.g. from an outlet device in contact or almost in contact, with the work for applying liquid or other fluent material to separate articles only at particular parts of the articles by relative movement of article and outlet according to a predetermined path

Abstract

The present invention is a method and device, which is suitable for use in an operating theater just prior to implantation, for selectively applying a medical coating to an implantable medical device (2), for example a stent.
Disclosed is a device for use with a stent(2) deployed on a catheter balloon.
The device is configured to apply a medical coating of a desired thickness to the surface of a stent (2) only. This is done by use of a drop-on-demand ink-jet (3a-3c) printing system in association with an optical scanning device (32a, 32b). The device is further configured so as to, if necessary, apply a plurality of layered coats, each layered coat being of a different coating material, and if appropriate, different thickness. The section of the housing in which the stent (2) is held during the coating procedure is detachable from the housing base. The detachable housing section may be easily cleaned and re-sterilized or simply disposed of.

Claims (52)

1. A coating device for selectively applying a coating to surfaces of an object, the device applying the coating based upon optical properties of the surfaces such that the coating is applied to surfaces of a first type and is not applied to surfaces of a second type, the first type of surface being optically distinguishable from the second type of surface, the coating device comprising:
(a) at least one object-holding element configured to hold the object while a coating is applied;
(b) at least one optical scanning device deployed so as to scan at least a portion of the object, said optical scanning device configured so as to produce output indicative of the types of surfaces of the object;
(c) at least one coating applicator deployed so as to deposit a fluid so as to coat at least a portion of the object;
(d) at least one fluid delivery system in fluid communication so as to supply said fluid to said coating applicator;
(e) a processing unit being responsive at least to said output so as to selectively activate said coating applicator, thereby applying said coating substantially only to surfaces of the first type; and (f) a drive system configured so as to provide relative motion between the surface of the object and said coating applicator, and between the surface of the object and said optical scanning device.
2. The coating device of claim 1, wherein said drive system is configured so as to rotate said object-holding element about an axis perpendicular to a direction of application of said coating applicator.
3. The coating device of claim 1, wherein said at least one object-holding element is implemented as two object-holding elements configured so as to simultaneously support the object at two different regions along a length of the object.
4. The coating device of claim 3, wherein said two object-holding elements are mechanically linked so as to rotate synchronously about a single axis, said axis being perpendicular to a direction of application of said coating applicator.
5. The coating device of claim 1, wherein said at least one coating applicator includes a pressure-pulse actuated drop-ejection system with at least one nozzle.
6. The coating device of claim 1, wherein a spatial relationship between said coating applicator and said object is variable.
7. The coating device of claim 6, wherein said spatial relationship is varied along a first axis that is parallel to a direction of application of said coating applicator, and a second axis that is perpendicular to said direction of application of said coating applicator.
8. The coating device of claim 7, wherein said coating applicator is displaceable relative to said object-holding element, said displacement being along said first axis and said second axis, thereby varying said spatial relationship.
9. The coating device of claim 8, wherein both said coating applicator and said optical scanning device are deployed on a displaceable applicator base, displaceable relative to said object-holding element, said displacement being along said first axis and said second axis, thereby varying said spatial relationship.
10. The coating device of claim 1, wherein said at least one coating applicator is implemented as a plurality of coating applicators and said at least one fluid delivery system is implemented as an equal number of fluid delivery systems, each fluid delivery system supplying a different fluid coating material to said coating applicator with which said each fluid delivery system is in fluid communication.
11. The coating device of claim 1, wherein the object is a catheter that includes a balloon portion on which a stent is deployed, such that said stent is a surface of the first type and said balloon is a surface of the second type surface.
12. The coating device of claim 1, wherein said processing unit is responsive to an indication of said relative motion so as to change operational parameters of the coating device as required.
13. The coating device of claim 1, wherein said object-holding element, said coating applicator, said optical scanning device, said drive system and at least a portion of said fluid delivery system are deployed within a housing that includes an application compartment.
14. The coating device of claim 13, wherein said housing includes a base housing section and a detachable housing section.
15. The coating device of claim 14, wherein said application compartment is defined by portions of both said base housing section and said detachable housing section.
16. The coating device of claim 15, wherein said base housing section includes said coating applicator, at least a portion of said fluid delivery system, said optical scanning device and said processing unit and at least a first portion of said drive system, and said detachable housing section includes said object-holding element and at least a second portion of said drive system.
17. The coating device of claim 16, wherein said base housing section includes at least one fluid delivery system.
18. The coating device of claim 17, wherein said detachable housing section is disposable.
19. The coating device of claim 13, wherein said application compartment is a substantially sterile environment.
20. The coating device of claim 13, wherein said coating applicator, and said fluid delivery system are included in a removable sub-housing, said removable sub-housing being deployed with in said application compartment and said removable housing being detachably connected to said processing unit.
21. A coating device for selectively applying a coating to surfaces of an object, the device applying the coating based upon optical properties of the surfaces such that the coating is applied to surfaces of a first type and is not applied to surfaces of a second type, the first type of surface being optically distinguishable from the second type of surface, the coating device comprising:
(a) a housing which includes an application compartment;
(b) at least one object-holding element deployed within said application compartment, said object-holding element configured to hold the object to which a coating is applied;
(c) a displaceable applicator base deployed within said application compartment, said applicator base including:

(i) at least one coating applicator aligned so as to deposit a fluid whereby at least a portion of the object is coated; and (ii) at least one optical scanning device deployed so as to scan at least a portion of the object, said optical scanning device configured so as to produce output indicative of the different types of surfaces of the object, said displacement of said applicator base resulting in a variance of a spatial relationship between said coating applicator base and the object;
(d) at least one fluid delivery system in fluid communication so as to supply said fluid to said coating applicator;
(e) a processing unit being responsive at least to said output so as to selectively activate said coating applicator, thereby applying said coating substantially only to surfaces of the first type; and (f) a drive system configured so as to provide relative motion between the surface of the object and said applicator base.
22. The coating device of.claim 21, wherein said housing includes a base housing section and a detachable housing section.
23. The coating device of claim 22, wherein said application compartment is defined by portions of both said base housing and said detachable housing section.
24. The coating device of claim 23, wherein said base housing section includes said displaceable applicator base, at least a portion of said fluid delivery system, and said processing unit, and at least a first portion of said drive system, and said detachable housing section includes said object-holding element and at least a second portion of said drive system.
25. The coating device of claim 24, wherein said base housing section includes at least one fluid delivery system.
26. The coating device of claim 25, wherein said detachable housing section is disposable.
27. The coating device of claim 21, wherein said drive system is configured so as to rotate said object-holding element about an axis perpendicular to a direction of application of said coating applicator.
28. The coating device of claim 21, wherein said at least one object-holding element is implemented as two object-holding elements configured so as to simultaneously support the object at two different regions along a length of the object.
29.The coating device of claim 28, wherein said two object-holding elements are mechanically linked so as to rotate synchronously about a single axis, said axis being perpendicular to a direction of application of said coating applicator.
30. The coating device of claim 21, wherein said at least one coating applicator includes a pressure-pulse actuated drop-ejection system with at least one nozzle.
31. The coating device of claim 21, wherein said at least one fluid delivery system is deployed in said base housing.
32. The coating device of claim 21, wherein said at least one coating applicator is implemented as a plurality of coating applicators and said at least one fluid delivery system is implemented as a like number of fluid delivery systems, each fluid delivery system supplying a different fluid coating material to said coating applicator with which said each fluid delivery system is in fluid communication.
33. The coating device of claim 21, wherein said coating applicator, and said fluid delivery system are included in a removable sub-housing, said removable sub-housing being detachably connected to said displaceable applicator base.
34. The coating device of claim 21, wherein said spatial relationship is varied along two axes, a first axis that is parallel to a direction of application of said coating applicator, and a second axis that is perpendicular to said direction of application of said coating applicator.
35. The coating device of claim 21, wherein the object is a catheter that includes a balloon portion on which a stent is deployed, such that said stent is a surface of the first type and said balloon is a surface of the second type.
36. The coating device of claim 21, wherein said processing unit is responsive to an indication of said relative motion so as to change operational parameters of the coating device as required.
37. A coating method for selectively applying a coating to surfaces of an object, the method applying the coating based upon optical properties of the surfaces such that the coating is applied to surfaces of a first type and is not applied to surfaces of a second type, the first type of surface being optically distinguishable from the second type of surface, the coating device comprising:
(a) generating relative movement between the object and at least one optical scanning device and at least one coating applicator;
(b) optically scanning at least a portion of the object by use of said at least one optical scanning device so as to produce output indicative of the different types of surfaces of the object;
(c) responding to said output by selectively activating said coating applicator, thereby applying the coating substantially only to surfaces of the first type.
38. The coating method of claim 37, wherein said relative movement includes rotating the object about an axis perpendicular to a direction of application of said coating applicator.
39. The coating method of claim 37, further comprising simultaneously supporting the object at two different regions along a length of the object.
40. The coating method of claim 37, wherein said selective activation includes selectively activating a pressure-pulse actuated drop-ejection system with at least one nozzle.
41. The coating method of claim 37, wherein said selective activation includes selectively activating a pressure-pulse actuated drop-ejection system with at least one nozzle that is included in a removable sub-housing, said removable sub-housing further including a fluid delivery system in fluid communication so as to supply coating material to said coating applicator.
42. The coating method of claim 37, wherein said applying is preformed by selectively activating one of a plurality of coating applicators, wherein said at least one coating applicator implemented as said plurality of coating applicators, each of said plurality of coating applicators applying a different coating.
43. The coating method of claim 42, wherein said applying is preformed by selectively activating, in sequence, said plurality of coating applicators, thereby applying a plurality of layered coats, each one of said plurality of layered coats being of a coating material that is different from adjacent layered coats.
44. The coating method of claim 37, wherein responding to said output includes said output being indicative of a balloon portion of catheter and a stent deployed on said balloon, such that said stent is a surface of the first type and said balloon is a surface of the second type.
45. The coating method of claim 37, wherein responding to said output includes said output being indicative only of a surface of the first type thereby applying the coating to substantially the entire surface of the object.
46. The coating method of claim 37, further comprising varying a spatial relationship between said coating applicator and the object.
47. The coating method of claim 46, wherein said varying is along two axes, a first axis that is parallel to a direction of application of said coating applicator, and a second axis that is perpendicular to said direction of application of said coating applicator.
48. The coating method of claim 47, wherein said varying is accomplished by displacing said coating applicator.
49. The coating method of claim 48, wherein said varying is accomplished by varying the spatial relationship between said object and a displaceable applicator base upon which said at least one coating applicator and said at least one optical scanning device are deployed.
50. The coating method of claim 49, wherein controlling said varying is accomplished by said processing unit.
51. The coating method of claim 37, further comprising responding to an indication of said relative motion so as to change operational parameters of the coating device as required.
52. The coating method of claim 37, wherein generating relative movement, said optically scanning at least a portion of the object, and said selectively activating said coating are preformed within a housing.
CA2485069A 2002-05-02 2003-05-01 Stent coating device Expired - Fee Related CA2485069C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/136,295 2002-05-02
US10/136,295 US6645547B1 (en) 2002-05-02 2002-05-02 Stent coating device
PCT/IB2003/002270 WO2003092909A1 (en) 2002-05-02 2003-05-01 Stent coating device

Publications (2)

Publication Number Publication Date
CA2485069A1 true CA2485069A1 (en) 2003-11-13
CA2485069C CA2485069C (en) 2011-09-13

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CA2485069A Expired - Fee Related CA2485069C (en) 2002-05-02 2003-05-01 Stent coating device

Country Status (9)

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US (8) US6645547B1 (en)
EP (2) EP1499450B1 (en)
AT (2) ATE548126T1 (en)
AU (1) AU2003228079A1 (en)
CA (1) CA2485069C (en)
DE (1) DE60324543D1 (en)
ES (1) ES2322344T3 (en)
IL (2) IL164983A0 (en)
WO (1) WO2003092909A1 (en)

Families Citing this family (124)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7208010B2 (en) 2000-10-16 2007-04-24 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
US6241762B1 (en) 1998-03-30 2001-06-05 Conor Medsystems, Inc. Expandable medical device with ductile hinges
US20040254635A1 (en) 1998-03-30 2004-12-16 Shanley John F. Expandable medical device for delivery of beneficial agent
DE20122506U1 (en) 2000-10-16 2005-12-08 Conor Medsystems, Inc., Menlo Park Expandable medical device for delivering a beneficial agent
US20040073294A1 (en) 2002-09-20 2004-04-15 Conor Medsystems, Inc. Method and apparatus for loading a beneficial agent into an expandable medical device
EP1258230A3 (en) 2001-03-29 2003-12-10 CardioSafe Ltd Balloon catheter device
US6682771B2 (en) * 2001-07-02 2004-01-27 Scimed Life Systems, Inc. Coating dispensing system and method using a solenoid head for coating medical devices
US7927650B2 (en) * 2001-08-20 2011-04-19 Innovational Holdings, Llc System and method for loading a beneficial agent into a medical device
GB0121980D0 (en) 2001-09-11 2001-10-31 Cathnet Science Holding As Expandable stent
CA2466432A1 (en) 2001-11-08 2003-05-15 Atrium Medical Corporation Intraluminal device with a coating containing a therapeutic agent
US20040186551A1 (en) 2003-01-17 2004-09-23 Xtent, Inc. Multiple independent nested stent structures and methods for their preparation and deployment
US7309350B2 (en) 2001-12-03 2007-12-18 Xtent, Inc. Apparatus and methods for deployment of vascular prostheses
US7147656B2 (en) 2001-12-03 2006-12-12 Xtent, Inc. Apparatus and methods for delivery of braided prostheses
US7137993B2 (en) 2001-12-03 2006-11-21 Xtent, Inc. Apparatus and methods for delivery of multiple distributed stents
US7182779B2 (en) 2001-12-03 2007-02-27 Xtent, Inc. Apparatus and methods for positioning prostheses for deployment from a catheter
US7294146B2 (en) 2001-12-03 2007-11-13 Xtent, Inc. Apparatus and methods for delivery of variable length stents
US7892273B2 (en) 2001-12-03 2011-02-22 Xtent, Inc. Custom length stent apparatus
US8080048B2 (en) 2001-12-03 2011-12-20 Xtent, Inc. Stent delivery for bifurcated vessels
US20030135266A1 (en) 2001-12-03 2003-07-17 Xtent, Inc. Apparatus and methods for delivery of multiple distributed stents
US7351255B2 (en) 2001-12-03 2008-04-01 Xtent, Inc. Stent delivery apparatus and method
US6645547B1 (en) * 2002-05-02 2003-11-11 Labcoat Ltd. Stent coating device
US7709048B2 (en) * 2002-05-02 2010-05-04 Labcoat, Ltd. Method and apparatus for coating a medical device
US7048962B2 (en) * 2002-05-02 2006-05-23 Labcoat, Ltd. Stent coating device
US7758636B2 (en) 2002-09-20 2010-07-20 Innovational Holdings Llc Expandable medical device with openings for delivery of multiple beneficial agents
US7192484B2 (en) * 2002-09-27 2007-03-20 Surmodics, Inc. Advanced coating apparatus and method
US8221495B2 (en) 2002-11-07 2012-07-17 Abbott Laboratories Integration of therapeutic agent into a bioerodible medical device
PL376752A1 (en) * 2002-11-07 2006-01-09 Abbott Laboratories Prosthesis having varied concentration of beneficial agent
US8524148B2 (en) * 2002-11-07 2013-09-03 Abbott Laboratories Method of integrating therapeutic agent into a bioerodible medical device
US7211150B1 (en) 2002-12-09 2007-05-01 Advanced Cardiovascular Systems, Inc. Apparatus and method for coating and drying multiple stents
US8318235B2 (en) * 2003-01-22 2012-11-27 Cordis Corporation Method for applying drug coating to a medical device in surgeon room
US8281737B2 (en) 2003-03-10 2012-10-09 Boston Scientific Scimed, Inc. Coated medical device and method for manufacturing the same
EP1610823B1 (en) 2003-03-28 2011-09-28 Innovational Holdings, LLC Implantable medical device with continuous agent concentration gradient
DE10318803B4 (en) * 2003-04-17 2005-07-28 Translumina Gmbh Device for applying active substances to surfaces of medical implants, in particular stents
US7482034B2 (en) * 2003-04-24 2009-01-27 Boston Scientific Scimed, Inc. Expandable mask stent coating method
US7241308B2 (en) 2003-06-09 2007-07-10 Xtent, Inc. Stent deployment systems and methods
WO2005011561A2 (en) * 2003-08-04 2005-02-10 Labcoat, Ltd. Stent coating apparatus and method
US20050048194A1 (en) * 2003-09-02 2005-03-03 Labcoat Ltd. Prosthesis coating decision support system
US20050058768A1 (en) * 2003-09-16 2005-03-17 Eyal Teichman Method for coating prosthetic stents
US7785653B2 (en) * 2003-09-22 2010-08-31 Innovational Holdings Llc Method and apparatus for loading a beneficial agent into an expandable medical device
US7198675B2 (en) 2003-09-30 2007-04-03 Advanced Cardiovascular Systems Stent mandrel fixture and method for selectively coating surfaces of a stent
EP1684824B1 (en) 2003-11-20 2015-08-12 The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. Portable hand pump for evacuation of fluids
US7403966B2 (en) * 2003-12-08 2008-07-22 Freescale Semiconductor, Inc. Hardware for performing an arithmetic function
US7326236B2 (en) 2003-12-23 2008-02-05 Xtent, Inc. Devices and methods for controlling and indicating the length of an interventional element
US7323006B2 (en) 2004-03-30 2008-01-29 Xtent, Inc. Rapid exchange interventional devices and methods
US20060240065A1 (en) * 2005-04-26 2006-10-26 Yung-Ming Chen Compositions for medical devices containing agent combinations in controlled volumes
US20050251152A1 (en) * 2004-05-05 2005-11-10 Atrium Medical Corp. Illuminated medicated ink marker
US8317859B2 (en) 2004-06-28 2012-11-27 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US20050288766A1 (en) 2004-06-28 2005-12-29 Xtent, Inc. Devices and methods for controlling expandable prostheses during deployment
US20060029720A1 (en) * 2004-08-03 2006-02-09 Anastasia Panos Methods and apparatus for injection coating a medical device
EP1811933B1 (en) 2004-09-28 2016-03-23 Atrium Medical Corporation Barrier layer
US9801982B2 (en) 2004-09-28 2017-10-31 Atrium Medical Corporation Implantable barrier device
US9012506B2 (en) 2004-09-28 2015-04-21 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US9000040B2 (en) 2004-09-28 2015-04-07 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US20060088596A1 (en) * 2004-09-28 2006-04-27 Atrium Medical Corporation Solubilizing a drug for use in a coating
US8367099B2 (en) 2004-09-28 2013-02-05 Atrium Medical Corporation Perforated fatty acid films
US8312836B2 (en) 2004-09-28 2012-11-20 Atrium Medical Corporation Method and apparatus for application of a fresh coating on a medical device
US8337475B2 (en) * 2004-10-12 2012-12-25 C. R. Bard, Inc. Corporeal drainage system
CN100374092C (en) * 2005-01-14 2008-03-12 大连理工大学 Medicinal coating production for vascular stand and electrostatic spraying apparatus
US7749553B2 (en) * 2005-01-31 2010-07-06 Boston Scientific Scimed, Inc. Method and system for coating a medical device using optical drop volume verification
ATE533522T1 (en) * 2005-03-31 2011-12-15 Innovational Holdings Llc SYSTEM AND METHOD FOR LOADING A BENEFICIAL AGENT INTO A MEDICAL DEVICE
US7320702B2 (en) 2005-06-08 2008-01-22 Xtent, Inc. Apparatus and methods for deployment of multiple custom-length prostheses (III)
US7938851B2 (en) 2005-06-08 2011-05-10 Xtent, Inc. Devices and methods for operating and controlling interventional apparatus
US20070032865A1 (en) * 2005-08-05 2007-02-08 Otis David R Prosthesis having a coating and systems and methods of making the same
WO2007038643A1 (en) 2005-09-26 2007-04-05 C.R. Bard, Inc. Catheter connection systems
US9427423B2 (en) 2009-03-10 2016-08-30 Atrium Medical Corporation Fatty-acid based particles
US9278161B2 (en) 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
CA2626030A1 (en) 2005-10-15 2007-04-26 Atrium Medical Corporation Hydrophobic cross-linked gels for bioabsorbable drug carrier coatings
US8051797B1 (en) 2005-11-07 2011-11-08 Boston Scientific Scimed, Inc. Device to stabilize and align a pre-mounted stent
US7833261B2 (en) * 2005-12-12 2010-11-16 Advanced Cardiovascular Systems, Inc. Severable support for a stent
US7976891B1 (en) 2005-12-16 2011-07-12 Advanced Cardiovascular Systems, Inc. Abluminal stent coating apparatus and method of using focused acoustic energy
US7867547B2 (en) 2005-12-19 2011-01-11 Advanced Cardiovascular Systems, Inc. Selectively coating luminal surfaces of stents
CA2646885A1 (en) 2006-03-20 2007-09-27 Xtent, Inc. Apparatus and methods for deployment of linked prosthetic segments
US8003156B2 (en) 2006-05-04 2011-08-23 Advanced Cardiovascular Systems, Inc. Rotatable support elements for stents
US7775178B2 (en) * 2006-05-26 2010-08-17 Advanced Cardiovascular Systems, Inc. Stent coating apparatus and method
US8097291B2 (en) * 2006-06-05 2012-01-17 Boston Scientific Scimed, Inc. Methods for coating workpieces
US20070281071A1 (en) * 2006-06-06 2007-12-06 Boston Scientific Scimed, Inc. Acoustically coating workpieces
US8603530B2 (en) 2006-06-14 2013-12-10 Abbott Cardiovascular Systems Inc. Nanoshell therapy
US8048448B2 (en) 2006-06-15 2011-11-01 Abbott Cardiovascular Systems Inc. Nanoshells for drug delivery
US8017237B2 (en) 2006-06-23 2011-09-13 Abbott Cardiovascular Systems, Inc. Nanoshells on polymers
US8679573B2 (en) * 2006-06-28 2014-03-25 Advanced Cardiovascular Systems, Inc. Stent coating method and apparatus
WO2008033199A1 (en) * 2006-09-12 2008-03-20 Boston Scientific Limited Liquid masking for selective coating of a stent
DE102006050221B3 (en) * 2006-10-12 2007-11-22 Translumina Gmbh Device for applying active substances on surfaces of medical implants, has retaining bracket at cartridge, where two cylindrical housing parts are provided, which are pluggable into each other and are sterilely sealed against each other
US8011316B2 (en) 2006-10-18 2011-09-06 Innovational Holdings, Llc Systems and methods for producing a medical device
US8733274B2 (en) * 2006-10-20 2014-05-27 Hewlett-Packard Development Company, L.P. Tube mounted inkjet printhead die
US7867548B2 (en) * 2006-10-27 2011-01-11 Hewlett-Packard Development Company, L.P. Thermal ejection of solution having solute onto device medium
WO2008057328A2 (en) 2006-11-06 2008-05-15 Atrium Medical Corporation Tissue separating device with reinforced support for anchoring mechanisms
US9492596B2 (en) 2006-11-06 2016-11-15 Atrium Medical Corporation Barrier layer with underlying medical device and one or more reinforcing support structures
NZ588816A (en) 2007-01-21 2011-11-25 Hemoteq Ag Medical device for the treatment of stenoses of corporal lumina and for the prevention of impending restenoses
US20080199510A1 (en) 2007-02-20 2008-08-21 Xtent, Inc. Thermo-mechanically controlled implants and methods of use
US8486132B2 (en) 2007-03-22 2013-07-16 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US8048441B2 (en) 2007-06-25 2011-11-01 Abbott Cardiovascular Systems, Inc. Nanobead releasing medical devices
AU2008326154B2 (en) 2007-10-30 2013-12-12 Uti Limited Partnership Method and system for sustained-release of sclerosing agent
AU2008322469B2 (en) 2007-11-14 2014-02-20 Biosensors International Group, Ltd. Automated coating apparatus and method
US9101503B2 (en) 2008-03-06 2015-08-11 J.W. Medical Systems Ltd. Apparatus having variable strut length and methods of use
EP3159033B1 (en) 2008-05-01 2019-02-27 Bayer Intellectual Property GmbH Catheter balloon drug adherence techniques and methods
US8821562B2 (en) 2008-09-25 2014-09-02 Advanced Bifurcation Systems, Inc. Partially crimped stent
US8226603B2 (en) 2008-09-25 2012-07-24 Abbott Cardiovascular Systems Inc. Expandable member having a covering formed of a fibrous matrix for intraluminal drug delivery
EP2344068B1 (en) 2008-09-25 2022-10-19 Advanced Bifurcation Systems Inc. Partially crimped stent
US8828071B2 (en) 2008-09-25 2014-09-09 Advanced Bifurcation Systems, Inc. Methods and systems for ostial stenting of a bifurcation
US8076529B2 (en) 2008-09-26 2011-12-13 Abbott Cardiovascular Systems, Inc. Expandable member formed of a fibrous matrix for intraluminal drug delivery
US11298252B2 (en) 2008-09-25 2022-04-12 Advanced Bifurcation Systems Inc. Stent alignment during treatment of a bifurcation
US8049061B2 (en) 2008-09-25 2011-11-01 Abbott Cardiovascular Systems, Inc. Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery
US8500687B2 (en) 2008-09-25 2013-08-06 Abbott Cardiovascular Systems Inc. Stent delivery system having a fibrous matrix covering with improved stent retention
US20100285085A1 (en) * 2009-05-07 2010-11-11 Abbott Cardiovascular Systems Inc. Balloon coating with drug transfer control via coating thickness
US20110038910A1 (en) 2009-08-11 2011-02-17 Atrium Medical Corporation Anti-infective antimicrobial-containing biomaterials
ES2654334T3 (en) * 2010-01-18 2018-02-13 Concept Medical Research Private Limited Method and system for coating insertable medical devices
CA2794064A1 (en) 2010-03-24 2011-09-29 Advanced Bifurcation Systems, Inc. Methods and systems for treating a bifurcation with provisional side branch stenting
EP2549952A4 (en) 2010-03-24 2017-01-04 Advanced Bifurcation Systems, Inc. System and methods for treating a bifurcation
CA2794078A1 (en) 2010-03-24 2011-09-29 Advanced Bifurcation Systems, Inc. Stent alignment during treatment of a bifurcation
US8389041B2 (en) 2010-06-17 2013-03-05 Abbott Cardiovascular Systems, Inc. Systems and methods for rotating and coating an implantable device
EP2593141B1 (en) 2010-07-16 2018-07-04 Atrium Medical Corporation Composition and methods for altering the rate of hydrolysis of cured oil-based materials
US20120035596A1 (en) * 2010-08-04 2012-02-09 Tegg Troy T Disposable Drive Interface for Longitudinal Movement of an Elongate Medical Device
CA2826760A1 (en) 2011-02-08 2012-08-16 Advanced Bifurcation Systems, Inc. Multi-stent and multi-balloon apparatus for treating bifurcations and methods of use
EP3449879B1 (en) 2011-02-08 2020-09-23 Advanced Bifurcation Systems Inc. System for treating a bifurcation with a fully crimped stent
WO2013121445A2 (en) * 2012-02-16 2013-08-22 Sahajanand Technologies Private Limited Drug coating apparatus
US9867880B2 (en) 2012-06-13 2018-01-16 Atrium Medical Corporation Cured oil-hydrogel biomaterial compositions for controlled drug delivery
CN104607339B (en) * 2015-01-22 2017-01-04 上海理工大学 Medicine spraying Z axis system
US10702281B2 (en) 2016-07-18 2020-07-07 Merit Medical Systems, Inc. Inflatable radial artery compression device
CN107029942B (en) * 2016-11-07 2020-11-03 深圳市万至达电机制造有限公司 Dispensing device for coreless motor rotor
CN109550617A (en) * 2018-12-11 2019-04-02 安徽江淮汽车集团股份有限公司 Gear Experimentation tooling
CN109759256B (en) * 2019-01-14 2020-03-24 沈阳马卡智工科技有限公司 Automatic paste painting machine
CN110302921B (en) * 2019-07-05 2021-03-19 江苏中泽电气自动化有限公司 Metal pipe fitting processing digit control machine tool
CN110449294B (en) * 2019-08-27 2020-12-22 临沂市皓正铁塔制造有限公司 Portable quick spraying equipment
CN110976128B (en) * 2019-12-12 2020-10-27 苏州德斯米尔智能科技有限公司 Outer surface treatment device for production and manufacturing of water purifier pressure barrel

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4249445A (en) 1979-07-02 1981-02-10 Browning Richard J Food slicing apparatus
DE3603126A1 (en) * 1986-02-01 1987-08-06 Schmalbach Lubeca METHOD AND DEVICE FOR APPLYING LIQUID CORROSION PROTECTIVE AGENTS ON CORROSION HAZARDOUS AREAS OF PACKAGING CONTAINERS OR CONTAINER PARTS
US4766844A (en) * 1987-05-28 1988-08-30 Westinghouse Electric Corp. Robotic tinning station for axial lead electronic components
US5426747A (en) * 1991-03-22 1995-06-20 Object Design, Inc. Method and apparatus for virtual memory mapping and transaction management in an object-oriented database system
DE69310187T2 (en) * 1992-12-23 1997-11-27 Taligent Inc OBJECT-ORIENTED FRAMEWORK SYSTEM
EP0664036B1 (en) * 1993-01-22 1997-06-11 Taligent, Inc. Flexible network system
AU6081994A (en) * 1993-01-22 1994-08-15 Taligent, Inc. Flexible system
WO1994025921A1 (en) * 1993-04-26 1994-11-10 Taligent, Inc. Text transliteration system
US5596696A (en) * 1993-05-10 1997-01-21 Object Technology Licensing Corp. Method and apparatus for synchronizing graphical presentations
CA2141931A1 (en) * 1993-06-03 1994-12-22 Robert David Dickinson Place object system
AU6081494A (en) * 1993-07-27 1995-02-28 Taligent, Inc. Object-oriented rendering system
US5429682A (en) * 1993-08-19 1995-07-04 Advanced Robotics Technologies Automated three-dimensional precision coatings application apparatus
US5566278A (en) * 1993-08-24 1996-10-15 Taligent, Inc. Object oriented printing system
EP0714531B1 (en) * 1993-09-13 1997-06-18 Taligent, Inc. Object-oriented video system
CA2153968A1 (en) * 1993-09-13 1995-03-23 Steven H. Milne Multimedia data routing system
AU6019194A (en) * 1993-10-29 1995-05-22 Taligent, Inc. Graphic editor framework system
WO1995015524A1 (en) * 1993-12-02 1995-06-08 Taligent, Inc. Method and apparatus for displaying hardware dependent graphics in an object-oriented operating system
AU7725794A (en) * 1993-12-30 1995-07-17 Taligent, Inc. Object-oriented view hierarchy framework
EP0679372B1 (en) 1994-04-25 1999-07-28 Advanced Cardiovascular Systems, Inc. Radiopaque stent markers
US6341293B1 (en) * 1994-07-13 2002-01-22 Object Technology Licensing Corp Real-time computer “garbage collector”
US5504892A (en) * 1994-09-08 1996-04-02 Taligent, Inc. Extensible object-oriented file system
US5652884A (en) * 1994-11-14 1997-07-29 Object Technology Licensing Corp. Method and apparatus for dynamic update of an existing object in an object editor
US5752245A (en) * 1994-12-09 1998-05-12 Object Technology Licensing Corporation Object-oriented system for configuration history management with a project workspace and project history database for draft identification
JPH08257957A (en) 1995-03-20 1996-10-08 Tokico Ltd Method for controlling industrial robot
US5857064A (en) * 1995-04-03 1999-01-05 Object Technology Licensing Corporation System for imaging complex graphical images
US5596503A (en) * 1995-05-12 1997-01-21 Flint; Mary L. Process for making a doll's head looking like the head of a living person
US5713045A (en) * 1995-06-29 1998-01-27 Object Technology Licensing Corporation System for processing user events with input device entity associated with event producer which further links communication from event consumer to the event producer
US5737599A (en) * 1995-09-25 1998-04-07 Rowe; Edward R. Method and apparatus for downloading multi-page electronic documents with hint information
DE69631428T2 (en) * 1995-10-13 2004-12-02 Nordson Corp., Westlake SYSTEM AND METHOD FOR COATING THE BASE OF FLIP CHIPS
US5713949A (en) 1996-08-06 1998-02-03 Jayaraman; Swaminathan Microporous covered stents and method of coating
US6042600A (en) 1996-04-26 2000-03-28 Rosenthal; David Radioactive medical devices for inhibiting a hyperplastic response of biological tissue
US5877768A (en) * 1996-06-19 1999-03-02 Object Technology Licensing Corp. Method and system using a sorting table to order 2D shapes and 2D projections of 3D shapes for rendering a composite drawing
US5871436A (en) 1996-07-19 1999-02-16 Advanced Cardiovascular Systems, Inc. Radiation therapy method and device
US5755781A (en) 1996-08-06 1998-05-26 Iowa-India Investments Company Limited Embodiments of multiple interconnected stents
US6129042A (en) * 1996-11-08 2000-10-10 Coburn Optical Industries, Inc. Process and machine for coating ophthalmic lenses
US6001311A (en) 1997-02-05 1999-12-14 Protogene Laboratories, Inc. Apparatus for diverse chemical synthesis using two-dimensional array
US6106454A (en) 1997-06-17 2000-08-22 Medtronic, Inc. Medical device for delivering localized radiation
US6171232B1 (en) 1997-06-26 2001-01-09 Cordis Corporation Method for targeting in vivo nitric oxide release
US5891507A (en) 1997-07-28 1999-04-06 Iowa-India Investments Company Limited Process for coating a surface of a metallic stent
US6306166B1 (en) * 1997-08-13 2001-10-23 Scimed Life Systems, Inc. Loading and release of water-insoluble drugs
US6056722A (en) * 1997-09-18 2000-05-02 Iowa-India Investments Company Limited Of Douglas Delivery mechanism for balloons, drugs, stents and other physical/mechanical agents and methods of use
US5972027A (en) 1997-09-30 1999-10-26 Scimed Life Systems, Inc Porous stent drug delivery system
US6129658A (en) 1997-12-10 2000-10-10 Varian Associates, Inc. Method and apparatus creating a radioactive layer on a receiving substrate for in vivo implantation
US6235340B1 (en) 1998-04-10 2001-05-22 Massachusetts Institute Of Technology Biopolymer-resistant coatings
US6280411B1 (en) * 1998-05-18 2001-08-28 Scimed Life Systems, Inc. Localized delivery of drug agents
US6224627B1 (en) * 1998-06-15 2001-05-01 Gore Enterprise Holdings, Inc. Remotely removable covering and support
US6214115B1 (en) 1998-07-21 2001-04-10 Biocompatibles Limited Coating
US6335029B1 (en) 1998-08-28 2002-01-01 Scimed Life Systems, Inc. Polymeric coatings for controlled delivery of active agents
US6312121B1 (en) * 1998-09-11 2001-11-06 Xerox Corporation Ink jet printing process
US6245104B1 (en) 1999-02-28 2001-06-12 Inflow Dynamics Inc. Method of fabricating a biocompatible stent
US6309380B1 (en) 1999-01-27 2001-10-30 Marian L. Larson Drug delivery via conformal film
US6368658B1 (en) 1999-04-19 2002-04-09 Scimed Life Systems, Inc. Coating medical devices using air suspension
JP3542304B2 (en) * 1999-06-16 2004-07-14 シャープ株式会社 Printing device and host device
US6287628B1 (en) * 1999-09-03 2001-09-11 Advanced Cardiovascular Systems, Inc. Porous prosthesis and a method of depositing substances into the pores
US6203551B1 (en) 1999-10-04 2001-03-20 Advanced Cardiovascular Systems, Inc. Chamber for applying therapeutic substances to an implant device
US6290722B1 (en) * 2000-03-13 2001-09-18 Endovascular Technologies, Inc. Tacky attachment method of covered materials on stents
AU2001265238A1 (en) * 2000-05-31 2001-12-11 Advanced Cardiovascular Systems Inc. An apparatus and method for forming a coating onto a surface of a prosthesis
US6395326B1 (en) * 2000-05-31 2002-05-28 Advanced Cardiovascular Systems, Inc. Apparatus and method for depositing a coating onto a surface of a prosthesis
US6555157B1 (en) * 2000-07-25 2003-04-29 Advanced Cardiovascular Systems, Inc. Method for coating an implantable device and system for performing the method
WO2002014078A2 (en) 2000-08-14 2002-02-21 Surface Logix, Inc. Deformable stamp for patterning three-dimensional surfaces
US6254632B1 (en) * 2000-09-28 2001-07-03 Advanced Cardiovascular Systems, Inc. Implantable medical device having protruding surface structures for drug delivery and cover attachment
US6689219B2 (en) * 2001-03-15 2004-02-10 Michael Antoine Birmingham Apparatus and method for dispensing viscous liquid material
US6676987B2 (en) * 2001-07-02 2004-01-13 Scimed Life Systems, Inc. Coating a medical appliance with a bubble jet printing head
US6669980B2 (en) * 2001-09-18 2003-12-30 Scimed Life Systems, Inc. Method for spray-coating medical devices
US6939376B2 (en) 2001-11-05 2005-09-06 Sun Biomedical, Ltd. Drug-delivery endovascular stent and method for treating restenosis
US6890722B2 (en) * 2001-11-23 2005-05-10 Syn X Pharma, Inc. HP biopolymer markers predictive of insulin resistance
US7445629B2 (en) * 2002-01-31 2008-11-04 Boston Scientific Scimed, Inc. Medical device for delivering biologically active material
US7291165B2 (en) * 2002-01-31 2007-11-06 Boston Scientific Scimed, Inc. Medical device for delivering biologically active material
US7326245B2 (en) * 2002-01-31 2008-02-05 Boston Scientific Scimed, Inc. Medical device for delivering biologically active material
US6645547B1 (en) 2002-05-02 2003-11-11 Labcoat Ltd. Stent coating device

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