CA2470659A1 - Containers for reading and handling diagnostic reagents and methods of using the same - Google Patents

Containers for reading and handling diagnostic reagents and methods of using the same Download PDF

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Publication number
CA2470659A1
CA2470659A1 CA002470659A CA2470659A CA2470659A1 CA 2470659 A1 CA2470659 A1 CA 2470659A1 CA 002470659 A CA002470659 A CA 002470659A CA 2470659 A CA2470659 A CA 2470659A CA 2470659 A1 CA2470659 A1 CA 2470659A1
Authority
CA
Canada
Prior art keywords
container
reagent
sensing device
lid portion
continuous tape
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002470659A
Other languages
French (fr)
Other versions
CA2470659C (en
Inventor
Steven C. Charlton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Healthcare LLC
Original Assignee
Bayer Healthcare LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare LLC filed Critical Bayer Healthcare LLC
Publication of CA2470659A1 publication Critical patent/CA2470659A1/en
Application granted granted Critical
Publication of CA2470659C publication Critical patent/CA2470659C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/4875—Details of handling test elements, e.g. dispensing or storage, not specific to a particular test method
    • G01N33/48764—Test tape taken off a spool
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00009—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with a sample supporting tape, e.g. with absorbent zones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0295—Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00009—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with a sample supporting tape, e.g. with absorbent zones
    • G01N2035/00019—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with a sample supporting tape, e.g. with absorbent zones cassette structures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1002—Reagent dispensers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/104998—Glucose, ketone, nitrate standard or control
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/110833—Utilizing a moving indicator strip or tape
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/113332—Automated chemical analysis with conveyance of sample along a test line in a container or rack

Abstract

A container with a rotatable lid for reading and handling diagnostic reagents in tape form comprising a body portion, a lid portion, a continuous tape, a reagent-sensing device, and a storage device. The body portion includes an inner and outer surface. The lid portion is attached to the body por-tion and is adapted to rotate from a closed position to an open position. The continuous tape includes a diagnostic rea-gent. The reagent-sensing device is attached to either the body portion or the lid portion and adapted to read the diag-nostic reagent. The storage device is attached to the body portion that is adapted to hold and dispense an unused portion of the continuous tape. During the rotation of the lid por-tion, the continuous tape is advanced from the first storage device and is extended over the reagent-sensing device.

Claims (41)

1. A container with a rotatable lid for reading and han-dling diagnostic reagents in tape form, comprising:
a body portion including an inner and outer surface;
a lid portion being attached to the body portion and being adapted to rotate from a closed position to an open position;
a continuous tape including a diagnostic reagent a reagent-sensing device being attached to either the body portion or the lid portion and adapted to read the di-agnostic reagents and a storage device being attached to the body portion that is adapted to hold and dispense an unused portion of the continuous tape, wherein during the rotation of the lid portion, the continuous tape is advanced from the storage device and is extended over the reagent-sensing device.
2. The container of claim 1, wherein the reagent-sensing device is attached to the inner surface of the body por-tion.
3. The container of claim 1, wherein the reagent-sensing device is attached to the outer surface of the body por-tion.
4. The container of claim 1, wherein the reagent-sensing device is attached to the lid portion.
5. The container of claim 1, further including a hinge to rotate the body portion and the lid portion from each other.
6. The container of claim 1, wherein the diagnostic rea-gent remains with the continuous tape during the advancing of the continuous tape.
7. The container of claim 1, wherein the diagnostic rea-gent is adapted to separate from the remainder of the con-tinuous tape during the advancing of the continuous tape.
8. The container of claim 1 further comprising a lancet.
9. The container of claim 1 further comprising a calibra-tion standard.
10. The container of claim 9, wherein the calibration standard is attached to the lid portion.
11. The container of claim 1, wherein the reagent-sensing device includes an electrochemical sensor.
12. The container of claim 1, wherein the reagent-sensing device includes an optical sensor.
13. The container of claim 1 further including means for moving the reagent-sensing device.
14. The container of claim 13, wherein means for moving the reagent-sensing device is a rack and pinion drive.
15. The container of claim 13, wherein means for moving the reagent-sensing device is a cam mechanism.
16. The container of claim 1, wherein the storage device is a spool.
17. The container of claim 1, wherein the body portion and the lid portion in the closed position form a sealed con-tainer adapted to store humidity-sensitive diagnostic rea-gents.
18. The container of claim 1 further comprising at least one seal that is located between the body portion and the lid portion when the lid portion is in a closed position.
19. The container of claim 1 further comprising a desic-cant.
20. The container of claim 1, wherein the continuous tape is Z-folded.
21. A container with a rotatable lid for reading and han-dling diagnostic reagents in tape form, comprising:
a body portion including an inner and outer surface;
a lid portion being attached to the body portion and being adapted to rotate from a closed position to an open posi-tion;
a continuous tape including a diagnostic reagent;
a reagent-sensing device being attached to either the body portion or the lid portion and adapted to read the di-agnostic reagent;
a first storage device being attached to the body por-tion that is adapted to hold and dispense an unused portion of the continuous tape; and a second storage device being attached to the lid por-tion that is adapted to receive a used portion of the con-tinuous tape, wherein during the rotation of the lid portion, the continuous tape is advanced from the first storage device and is extended over the reagent-sensing device and re-ceived by the second storage device.
22. The container of claim 21, wherein the first and sec-ond storage devices are spools.
23. The container of claim 21, wherein the reagent-sensing device is attached to the inner surface of the body por-tion.
24. The container of claim 21, wherein the reagent-sensing device is attached to the outer surface of the body por-tion.
25. The container of claim 21, wherein the diagnostic rea-gent remains with the continuous tape during the advancing of the continuous tape.
26. The container of claim 21 further comprising a cali-bration standard.
27. The container of claim 21, wherein the reagent-sensing device includes an electrochemical sensor.
28. The container of claim 21, wherein the reagent-sensing device includes an optical sensor.
29. The container of claim 21, further including means for moving the reagent-sensing device.
30. The container of claim 21 further comprising at least one seal that is located between the body portion and the lid portion when the lid portion is in a closed position.
31. The container of claim 21 further comprising a desic-cant.
32. A container with a rotatable lid for reading and han-dling diagnostic reagents adapted to determine glucose con-centration in tape form, comprising:
a body portion including an inner and outer surface;

a lid portion being attached to the body portion and being adapted to rotate from a closed position to an open position;
a continuous tape including a diagnostic reagent to determine glucose concentration;
a reagent-sensing device being attached to either the body portion or the lid portion and adapted to read the di-agnostic reagent; and a first storage device being attached to the body por-tion that is adapted to hold and dispense an unused portion of the continuous tape, wherein during the rotation of the lid portion, the continuous tape is advanced from the first storage device and is extended over the reagent-sensing device.
33. The container of 32 further including a second storage device.
34. The container of claim 32 further comprising at least one seal that is located between the body portion and the lid portion when the lid portion is in a closed position.
35. The container of claim 32 further comprising a desic-cant.
36. A method of using a container with a rotatable lid for reading and handling diagnostic reagents in tape form, com-prising:
providing a rotatable container comprising a body por-tion, a lid portion, a continuous tape, a reagent-sensing device and a first storage device, the body portion includ-ing an inner and outer surface, the lid portion being at-tached to the body portion, the continuous tape including a diagnostic reagent, the reagent-sensing device being at-tached to either the body portion or the lid portion and adapted to read the diagnostic reagent, the first storage device being attached to the body portion and being adapted to hold and dispense an unused portion of the continuous tape;
rotating the lid portion from a closed position to an open position; and advancing the continuous tape from the first storage device to extend over the reagent-sensing device during the rotation of the lid portion.
37. The method of claim 36, wherein the container further includes a second storage device that is attached to the lid portion and wherein during the advancing of the con-tinuous tape, the second storage device receives the used portion of the continuous tape.
38. The method of claim 36 further comprising rotating the lid portion from the open position to the closed position and wherein during the rotation of the lid portion to the closed position, moving the continuous tape from the rea-gent-sensing device.
39. The method of claim 36 further including placing a body fluid on the unused portion of the continuous tape over the reagent-sensing device and determining the concen-tration of an analyte of the body fluid from the reagent-sensing device.
40. The method of claim 39, wherein the analyte is glucose and the body fluid is a whole blood sample.
41. The method of claim 36 further including placing a whole blood sample on the unused portion of the continuous tape over the reagent-sensing device and determining the concentration of glucose of the whole blood sample from the reagent-sensing device.
CA2470659A 2003-06-18 2004-06-10 Containers for reading and handling diagnostic reagents and methods of using the same Expired - Fee Related CA2470659C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47917003P 2003-06-18 2003-06-18
US60/479,170 2003-06-18

Publications (2)

Publication Number Publication Date
CA2470659A1 true CA2470659A1 (en) 2004-12-18
CA2470659C CA2470659C (en) 2012-10-02

Family

ID=33418478

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2470659A Expired - Fee Related CA2470659C (en) 2003-06-18 2004-06-10 Containers for reading and handling diagnostic reagents and methods of using the same

Country Status (6)

Country Link
US (4) US7364699B2 (en)
EP (1) EP1488736B1 (en)
JP (2) JP4409370B2 (en)
AU (1) AU2004202220A1 (en)
CA (1) CA2470659C (en)
DE (1) DE602004020705D1 (en)

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US7749454B2 (en) 2010-07-06
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US7364699B2 (en) 2008-04-29
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