CA2465360A1 - Catamenial device having antibacterial properties - Google Patents

Catamenial device having antibacterial properties Download PDF

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Publication number
CA2465360A1
CA2465360A1 CA002465360A CA2465360A CA2465360A1 CA 2465360 A1 CA2465360 A1 CA 2465360A1 CA 002465360 A CA002465360 A CA 002465360A CA 2465360 A CA2465360 A CA 2465360A CA 2465360 A1 CA2465360 A1 CA 2465360A1
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CA
Canada
Prior art keywords
absorbent product
group
quaternary ammonium
surfactants
total weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002465360A
Other languages
French (fr)
Other versions
CA2465360C (en
Inventor
Anthony J. Mauro
Mark E. Rosengarten
Irwin Butensky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Edgewell Personal Care Brands LLC
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Individual
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Filing date
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Publication of CA2465360A1 publication Critical patent/CA2465360A1/en
Application granted granted Critical
Publication of CA2465360C publication Critical patent/CA2465360C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/48—Surfactants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/202—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with halogen atoms, e.g. triclosan, povidone-iodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
    • A61L2300/208—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
    • A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S604/00—Surgery
    • Y10S604/904—Tampons

Abstract

There is provided a fibrous absorbent article for absorbing body fluids made up of a fibrous material defining a structure suitable for absorbing the bod y fluids, and disposed within the stucture an effective amount, so as to reduc e Staphylococcus aureus bacterial growth and neutralize TSS toxin-1 within the vagina, of one or more antimicrobial agents and one or more finishing agents .

Claims (38)

1. An absorbent product comprising an absorbent material and a composition disposed within said absorbent material, the composition having:
at least one antibacterial agent; and at least one finishing agent, wherein the composition has synergistic antibacterial properties effective to neutralize the production of toxin and reduce Staphylococcus aureus bacteria growth.
2. The absorbent product of claim 1, wherein said at least one antibacterial agent is selected from the group consisting of: quaternary ammonium compound, glyceryl monolaurate, 5-chloro-2-(2,4-dichlorophenoxy)-2,4,4'-trichloro-2'-hydroxy diphenyl ether (triclosan), p-chloro-m-xylenol, N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl) urea (triclocarban), 2-N-octyl-4-isothiazolin-3-one, iodine-based compounds, and any mixtures thereof.
3. The absorbent product of claim 1, wherein said at least one antibacterial agent is one or more quaternary ammonium compounds.
4. The absorbent product of claim 3, wherein said one or more quaternary ammonium compounds have a chemical structure:
wherein X is selected from the group consisting of: a halogen and a saccharinate; R1 and R3 is a straight or branched C1-C4 alkyl; R2 is a straight or branched C6-C22 alkyl; and R4 is of the chemical structure:
wherein R5 is selected from the group consisting of: H, a straight or branched C1-C4 alkyl group, and a halogen.
5. The absorbent product of claim 4, wherein said one or more quaternary ammonium compounds are selected from the group consisting of: alkyl dimethyl benzylammonium chloride, alkyl dimethyl ethylbenzylammonium chloride, myristyl dimethyl benzylammonium chloride, lauryl dimethyl ethylbenzylammonium chloride, alkyl dimethyl benzylammonium bromide, alkyl dimethyl benzylammonium cetyl phosphate, alkyl dimethyl benzylammonium saccharinate, and any mixtures thereof.
6. The absorbent product of claim 4, wherein said one or more quaternary ammonium compounds are a mixture of alkyl dimethyl benzylammonium chloride and alkyl dimethyl ethylbenzylammonium chloride.
7. The absorbent product of claim 6, wherein said quaternary ammonium compounds are present in an amount of about 1.0 wt.% based on the total weight of the absorbent product.
8. The absorbent product of claim 3, wherein said quaternary ammonium compounds are present in an amount about 0.01 wt.% to about 5 wt.% based on the total weight of the absorbent product.
9. The absorbent product of claim 1, wherein said at least one antibacterial agent is present in the absorbent product in an amount about 0.01 wt.% to about wt.% based on the total weight of the absorbent product.
10. The absorbent product of claim 1, wherein said at least one finishing agent is one or more surfactants.
11. The absorbent product of claim 10, wherein said one or more surfactants are selected from the group consisting of nonionic, anionic, cationic, amphoteric, and any mixtures thereof.
12. The absorbent product of claim 10, wherein said one or more surfactants are present in an amount about 0.01 wt.% to about 10 wt.% based on the total weight of the absorbent product.
13. The absorbent product of claim 10, wherein said one or more surfactants are one or more nonionic surfactants.
14. The absorbent product of claim 10, wherein said one or more nonionic surfactants are selected from the group consisting of one or more: alcohol ethoxylates, alkylphenol ethoxylates, carboxylic acid esters, ethoxylated anhydrosorbital esters, glycerol esters, poly(oxyethylene-co-oxypropylene) based surfactants, polyoxyethylene fatty acid amines, polyoxyethylene fatty acid esters, polyethylene glycol, polyethylene glycol esters, and any mixtures thereof.
15. The absorbent product of claim 14, wherein said one or more nonionic surfactants are one or more polyoxyethylene fatty acid esters.
16. The absorbent product of claim 15, wherein said polyoxyethylene fatty acid ester is present in an amount about 2.5 wt.% based on the total weight of the absorbent product.
17 17. The absorbent product of claim 1, wherein said at least one finishing agent is present in an amount about 0.01 wt.% to about 10 wt.% based on the total weight of the absorbent product.
18. The absorbent product of claim 1, wherein said absorbent product is selected from the group consisting of:

catamenial tampons, wound dressings, disposable diapers, sanitary napkins, medical tampons, surgical tampons, dental tampons, and nasal tampons.
19. The absorbent product of claim 1, wherein said composition further comprises one or more additional components selected from the group consisting of: preservative, deodorant, fragrance, malodor counteractant material, humectant, and any combinations thereof.
20. A method of inhibiting the production of TSST-1 toxin by exposing TSST-1 toxin-producing Staphylococcus aureus bacteria to an absorbent product, the absorbent product having an absorbent material and a composition, the composition comprising:
at least one antibacterial agent; and at least one finishing agent, wherein the composition effectively neutralizes the production of toxin and reduces Staphylococcus aureus bacteria growth.
21. The method of claim 20, wherein said at least one antibacterial agent is selected from the group consisting of: quaternary ammonium compound, glyceryl monolaurate, 5-chloro-2-(2,4-dichlorophenoxy)-2,4,4'-trichloro-2'-hydroxy diphenyl ether (triclosan), p-chloro-m-xylenol, N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl) urea (triclocarban), 2-N-octyl-4-isothiazolin-3-one, iodine-based compounds, and any mixtures thereof.
22. The absorbent product of claim 21, wherein said at least one antibacterial agent is one or more quaternary ammonium compounds.
23. The method of claim 22, wherein said one or more quaternary ammonium compounds has a chemical structure:
wherein X is selected from the group consisting of: a halogen and a saccharinate; R1 and R3 is a straight or branched C1-C4 alkyl; R2 is a straight or branched C6-C22 alkyl; and R4 is of the chemical structure:
wherein R5 is selected from the group consisting of: H, a straight or branched C1-C4 alkyl group, and a halogen.
24. The method of claim 22, wherein said quaternary ammonium compounds are present in an amount about 0.01 wt.% to about 5 wt.% based on the total weight of the absorbent product.
25. The absorbent product of claim 21, wherein said one or more quaternary ammonium compounds are selected from the group consisting of: alkyl dimethyl benzylammonium chloride, alkyl dimethyl ethylbenzylammonium chloride, myristyl dimethyl benzylammonium chloride, lauryl dimethyl ethylbenzylammonium chloride, alkyl dimethyl benzylammonium bromide, alkyl dimethyl benzylammonium cetyl phosphate, alkyl dimethyl benzylammonium saccharinate, and any mixtures thereof.
26. The method of claim 25, wherein said one or more quaternary ammonium compounds are a mixture of alkyl dimethyl benzylammonium chloride and alkyl dimethyl ethylbenzylammonium chloride.
27. The method of claim 25, wherein said one or more quaternary ammonium compounds are present in an amount about 1.0 wt.% based on the total weight of the absorbent product.
28. The method of claim 20, wherein said at least one antibacterial agent is present in an amount about 0.01 wt.o to about 5 wt.% based on the total weight of the absorbent product.
29. The method of claim 20, wherein said at least one finishing agent is one or more surfactants.
30. The method of claim 29, wherein said one or more surfactants are selected from the group consisting of: nonionic, anionic, cationic, amphoteric, and any mixtures thereof.
31. The method of claim 29, wherein said one or more surfactants are one or more nonionic surfactants.
32. The method of claim 31, wherein said one or more nonionic surfactants are selected from the group consisting of: alcohol ethoxylates, alkylphenol ethoxylates, carboxylic acid esters, ethoxylated anhydrosorbital esters, glycerol esters, poly(oxyethylene-co-oxypropylene) based surfactants, polyoxyethylene fatty acid amines, polyoxyethylene fatty acid esters, polyethylene glycol, polyethylene glycol esters, and any mixtures thereof.
33. The method of claim 32, wherein said one or more nonionic surfactants are one or more polyoxyethylene fatty acid esters.
34. The method of claim 33, wherein said one or more polyoxyethylene fatty acid esters are present in an amount about 2.5 wt.% based on the total weight of the absorbent product.
35. The method of claim 20, wherein said at least one finishing agent is present in an amount about 0.01 wt.o to about 10 wt.% based on the total weight of the absorbent product.
36. The method of claim 29, wherein said one or more surfactants are present in an amount about 0.01 wt.o to about 10 wt.% based on the total weight of the absorbent product.
37. The method of claim 20, wherein said absorbent product is selected from the group consisting of: catamenial tampons, wound dressings, disposable diapers, sanitary napkins, medical tampons, surgical tampons, dental tampons, and nasal tampons.
38. The method of claim 20, wherein said composition further comprises one or more additional components selected from the group consisting of:
preservative, deodorant, fragrance, malodor counteractant material, humectant and any combinations thereof.
CA2465360A 2001-11-02 2002-08-15 Catamenial device having antibacterial properties Expired - Fee Related CA2465360C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/003,915 2001-11-02
US10/003,915 US7745686B2 (en) 2001-11-02 2001-11-02 Catamenial device
PCT/US2002/026053 WO2003039401A2 (en) 2001-11-02 2002-08-15 Catamenial device

Publications (2)

Publication Number Publication Date
CA2465360A1 true CA2465360A1 (en) 2003-05-15
CA2465360C CA2465360C (en) 2011-11-22

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Family Applications (1)

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CA2465360A Expired - Fee Related CA2465360C (en) 2001-11-02 2002-08-15 Catamenial device having antibacterial properties

Country Status (5)

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US (1) US7745686B2 (en)
JP (1) JP4319037B2 (en)
AU (1) AU2002324718A1 (en)
CA (1) CA2465360C (en)
WO (1) WO2003039401A2 (en)

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Also Published As

Publication number Publication date
CA2465360C (en) 2011-11-22
US20030100871A1 (en) 2003-05-29
US7745686B2 (en) 2010-06-29
WO2003039401A3 (en) 2003-08-28
JP2006501865A (en) 2006-01-19
AU2002324718A1 (en) 2003-05-19
WO2003039401A2 (en) 2003-05-15
JP4319037B2 (en) 2009-08-26

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