CA2462718A1 - Blood processing systems and methods that alternate flow of blood component and additive solution through an in-line leukofilter - Google Patents
Blood processing systems and methods that alternate flow of blood component and additive solution through an in-line leukofilter Download PDFInfo
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- CA2462718A1 CA2462718A1 CA002462718A CA2462718A CA2462718A1 CA 2462718 A1 CA2462718 A1 CA 2462718A1 CA 002462718 A CA002462718 A CA 002462718A CA 2462718 A CA2462718 A CA 2462718A CA 2462718 A1 CA2462718 A1 CA 2462718A1
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- blood
- blood cells
- blood cell
- filter
- storage container
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0218—Multiple bag systems for separating or storing blood components with filters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
- A61M1/301—Details
- A61M1/302—Details having a reservoir for withdrawn untreated blood
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
- A61M1/301—Details
- A61M1/303—Details having a reservoir for treated blood to be returned
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
- A61M1/301—Details
- A61M1/305—Control of inversion point between collection and re-infusion phase
- A61M1/308—Volume control, e.g. with open or flexible containers, by counting the number of pump revolutions, weighing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
- A61M1/36225—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit with blood pumping means or components thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
- A61M1/36226—Constructional details of cassettes, e.g. specific details on material or shape
- A61M1/362261—Constructional details of cassettes, e.g. specific details on material or shape at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
- A61M1/36226—Constructional details of cassettes, e.g. specific details on material or shape
- A61M1/362265—Details of valves
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
- A61M1/3633—Blood component filters, e.g. leukocyte filters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
- A61M1/3633—Blood component filters, e.g. leukocyte filters
- A61M1/3635—Constructional details
- A61M1/3636—Constructional details having a flexible housing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
- A61M1/36222—Details related to the interface between cassette and machine
- A61M1/362227—Details related to the interface between cassette and machine the interface providing means for actuating on functional elements of the cassette, e.g. plungers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
- A61M1/36226—Constructional details of cassettes, e.g. specific details on material or shape
- A61M1/362266—Means for adding solutions or substances to the blood
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
- A61M2205/128—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit with incorporated valves
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3306—Optical measuring means
- A61M2205/331—Optical measuring means used as turbidity change detectors, e.g. for priming-blood or plasma-hemoglubine-interface detection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3379—Masses, volumes, levels of fluids in reservoirs, flow rates
- A61M2205/3393—Masses, volumes, levels of fluids in reservoirs, flow rates by weighing the reservoir
Abstract
Blood processing systems and methods (10) convey blood cells from a blood ce ll source into a blood component collection flow channel that includes a blood cell storage container and an in-line filter to remove leukocytes from blood cells before entering the blood cell storage container. The systems and methods also convey additive solution from an additive solution source into the blood component collection flow channel. The systems and methods alterna te the conveyance of blood cells through the filter with the conveyance of additive solution through the filter.
Claims (17)
1. A blood processing system comprising a source of blood cells, a blood cell storage container, a source of an additive solution for blood cells, a blood component collection flow channel communicating with the blood cell storage container and including and an in-line filter to remove leukocytes from blood cells before entering the blood cell storage container, a pumping mechanism communicating with the blood component collection flow channel, and a controller to operate the pumping mechanism in different modes, including a first mode to convey blood cells from the blood cell source into the blood component collection flow channel and a second mode for conveying additive solution from the additive solution source into the blood component collection flow channel, the controller including a function to alternate the first and second modes.
2. A system according to claim 1 wherein the function alternates the first and second modes to achieve a desired ratio between blood cell volume and additive solution volume in the blood cell storage container.
3. A system according to claim 1 wherein the function terminates the first mode when a desired volume of blood cells has been conveyed from the blood cell source and operates the pumping mechanism in the second mode to flush residual blood cells from the filter into the red blood cell storage container.
4. A system according to claim 1 wherein the pumping mechanism includes a fluid pressure actuated pump and an actuator to apply fluid pressure to the pump.
5. A system according to claim 1 wherein the pumping mechanism includes a fluid pressure actuated pump housed within a cassette and an external actuator to receive the cassette and operate the fluid pressure actuated pump, and wherein the controller is coupled to the external actuator.
6. A system according to claim 1 wherein the filter includes a fibrous filter medium.
7. A system according to claim 1 wherein the filter includes a filter medium and a housing enclosing the filter medium.
8. A system according to claim 7 wherein the housing comprises a flexible material.
9. A system according to claim 8 further including a fixture to restrain expansion of the housing during operation of the pumping mechanism.
10. A system according to claim 1 wherein the controller includes,a function to derive a value reflecting volume of blood cells present in the blood cell collection container after passage through the filter as a percentage of volume of blood cells conveyed from the red blood cell source to the filter.
11. A system according to claim 1 wherein the blood cells comprise red blood cells.
12. A blood processing method comprising the steps of (a) conveying blood cells from a blood cell source into a blood component collection flow channel that includes a blood cell storage container and an in-line filter to remove leukocytes from blood cells before entering the blood cell storage container, (b) conveying additive solution from an additive solution source into the blood component collection flow channel, and (c) alternating steps (a) and (b)..
13. A method according to claim 12 wherein step (c) alternates steps (a) and (b) to achieve a desired ratio between blood cell volume and additive solution volume in the blood cell storage container.
14. A method according to claim 12 further including a step (d) comprising terminating step (a) when a desired volume of blood cells has been conveyed from the blood cell source and performing step (b) to flush residual blood cells from the filter into the blood cell storage container.
15. A method according to claim 12 further including a step of holding the filter in a restraining fixture during steps (a) and (b).
16. A method according to claim 12 further including a step of deriving a value reflecting volume of blood cells present in the blood cell collection container after passage through the filter as a percentage of volume of blood cells conveyed from the blood cell source to the filter.
17. A method according to claim 12 wherein the blood cells comprise red blood cells.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/976,832 US6875191B2 (en) | 1999-09-03 | 2001-10-13 | Blood processing systems and methods that alternate flow of blood component and additive solution through an in-line leukofilter |
US09/976,832 | 2001-10-13 | ||
PCT/US2002/031317 WO2003033046A2 (en) | 2001-10-13 | 2002-10-02 | Blood processing systems and methods that alternate flow of blood component and additive solution through an in-line leukofilter |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2462718A1 true CA2462718A1 (en) | 2003-04-24 |
CA2462718C CA2462718C (en) | 2010-08-17 |
Family
ID=25524524
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2462718A Expired - Lifetime CA2462718C (en) | 2001-10-13 | 2002-10-02 | Blood processing systems and methods that alternate flow of blood component and additive solution through an in-line leukofilter |
Country Status (8)
Country | Link |
---|---|
US (2) | US6875191B2 (en) |
EP (1) | EP1441800B1 (en) |
JP (1) | JP2005534346A (en) |
CN (1) | CN100413553C (en) |
AU (1) | AU2002332008B2 (en) |
BR (1) | BR0213200A (en) |
CA (1) | CA2462718C (en) |
WO (1) | WO2003033046A2 (en) |
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US6875191B2 (en) * | 1999-09-03 | 2005-04-05 | Baxter International Inc. | Blood processing systems and methods that alternate flow of blood component and additive solution through an in-line leukofilter |
US6890291B2 (en) | 2001-06-25 | 2005-05-10 | Mission Medical, Inc. | Integrated automatic blood collection and processing unit |
US7074172B2 (en) * | 2002-08-02 | 2006-07-11 | Zymequest, Inc. | Processing bag for component separator system and method of removing separated components |
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JP4861649B2 (en) * | 2005-07-08 | 2012-01-25 | テルモ株式会社 | Blood component collection circuit and blood component collection device |
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JP5215412B2 (en) * | 2007-12-26 | 2013-06-19 | テルモ ビーシーティー、インコーポレーテッド | Apparatus for the controlled addition of solvents to blood components |
US8211049B2 (en) * | 2008-02-26 | 2012-07-03 | Fenwal, Inc. | Blood processing system for single or double access draw and return |
US8075468B2 (en) * | 2008-02-27 | 2011-12-13 | Fenwal, Inc. | Systems and methods for mid-processing calculation of blood composition |
US8685258B2 (en) * | 2008-02-27 | 2014-04-01 | Fenwal, Inc. | Systems and methods for conveying multiple blood components to a recipient |
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USD734467S1 (en) | 2014-03-24 | 2015-07-14 | Fenwal, Inc. | Blood filter |
US10376627B2 (en) | 2014-03-24 | 2019-08-13 | Fenwal, Inc. | Flexible biological fluid filters |
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JP6533826B2 (en) * | 2014-08-29 | 2019-06-19 | フレゼニウス カービ ドイチュラント ゲーエムベーハー | Tube set used in blood processing apparatus |
JP6560744B2 (en) * | 2014-08-29 | 2019-08-14 | フレゼニウス カービ ドイチュラント ゲーエムベーハー | Blood processing apparatus comprising a holder device for a measuring instrument |
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US9827365B2 (en) * | 2015-11-02 | 2017-11-28 | Fenwal, Inc. | Systems and methods for automated air removal in products comprising biological fluids |
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EP3993846A1 (en) | 2019-07-22 | 2022-05-11 | TERUMO Kabushiki Kaisha | Flow path device and biological component bag system |
JP7441932B2 (en) | 2019-07-22 | 2024-03-01 | テルモ株式会社 | Flow path device and biological component bag system |
JPWO2022176600A1 (en) * | 2021-02-18 | 2022-08-25 |
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-
2001
- 2001-10-13 US US09/976,832 patent/US6875191B2/en not_active Expired - Lifetime
-
2002
- 2002-10-02 JP JP2003535847A patent/JP2005534346A/en not_active Withdrawn
- 2002-10-02 CN CNB028202694A patent/CN100413553C/en not_active Expired - Lifetime
- 2002-10-02 EP EP02768944.7A patent/EP1441800B1/en not_active Expired - Lifetime
- 2002-10-02 CA CA2462718A patent/CA2462718C/en not_active Expired - Lifetime
- 2002-10-02 WO PCT/US2002/031317 patent/WO2003033046A2/en active Application Filing
- 2002-10-02 BR BRPI0213200-1A patent/BR0213200A/en unknown
- 2002-10-02 AU AU2002332008A patent/AU2002332008B2/en not_active Expired
-
2005
- 2005-01-10 US US11/032,271 patent/US7357897B2/en not_active Expired - Fee Related
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BR0213200A (en) | 2006-05-23 |
US7357897B2 (en) | 2008-04-15 |
AU2002332008B2 (en) | 2008-07-10 |
EP1441800B1 (en) | 2013-06-19 |
CN1568206A (en) | 2005-01-19 |
CN100413553C (en) | 2008-08-27 |
CA2462718C (en) | 2010-08-17 |
WO2003033046A2 (en) | 2003-04-24 |
US6875191B2 (en) | 2005-04-05 |
EP1441800A2 (en) | 2004-08-04 |
US20020131891A1 (en) | 2002-09-19 |
EP1441800A4 (en) | 2009-10-21 |
JP2005534346A (en) | 2005-11-17 |
WO2003033046A3 (en) | 2004-03-11 |
US20050124927A1 (en) | 2005-06-09 |
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