CA2460895A1 - Method of controlling a dialysis apparatus - Google Patents

Method of controlling a dialysis apparatus Download PDF

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Publication number
CA2460895A1
CA2460895A1 CA002460895A CA2460895A CA2460895A1 CA 2460895 A1 CA2460895 A1 CA 2460895A1 CA 002460895 A CA002460895 A CA 002460895A CA 2460895 A CA2460895 A CA 2460895A CA 2460895 A1 CA2460895 A1 CA 2460895A1
Authority
CA
Canada
Prior art keywords
controlling
transmembrane pressure
flow rate
replacement fluid
threshold
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002460895A
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French (fr)
Other versions
CA2460895C (en
Inventor
Anders Felding
Jan Sternby
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Gambro Lundia AB
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Individual
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Application filed by Individual filed Critical Individual
Publication of CA2460895A1 publication Critical patent/CA2460895A1/en
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Publication of CA2460895C publication Critical patent/CA2460895C/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601—Control or regulation
    • A61M1/1603—Regulation parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601—Control or regulation
    • A61M1/1603—Regulation parameters
    • A61M1/1611—Weight of the patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601—Control or regulation
    • A61M1/1613—Profiling or modelling of patient or predicted treatment evolution or outcome
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3403—Regulation parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3403—Regulation parameters
    • A61M1/341—Regulation parameters by measuring the filtrate rate or volume
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342—Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3441—Substitution rate control as a function of the ultrafiltration rate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24—Dialysis ; Membrane extraction
    • B01D61/32—Controlling or regulating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3334—Measuring or controlling the flow rate

Abstract

The present invention relates to a method of controlling a dialysis apparatus, which can be used for e.g. hemodialysis, hemodiafiltration or hemofiltration.
Numerous alarms occur during treatments creating additional workloads for the operator. The present method of controlling the apparatus allows an automatic switch form a first control mode to another, thus allowing the treatment to continue without operator interference.

Claims (12)

1. Method of controlling a dialysis apparatus comprising the steps of:
- observing at least two parameters related to the dialysis, - determine a range of acceptable values for said parameters - controlling one of said parameters, - switching to controlling one of the other of said parameters when one of the other of said parameters is outside the respective range of acceptable values.
2. Method according to claim1, wherein the controlled parameter is controlled so as to maintain a predetermined value or follow a predetermined profile
3. Method according to claim 1 or 2 , wherein said dialyses apparatus is suitable for hemodialysis, and/or hemodiafiltration and/or hemofiltration.
4. Method according to any of the preceding claims, in which said at least two parameters comprise transmembrane pressure and ultrafiltration flow rate.
5. Method according to claims 1 to 3, in which said at least two parameters comprise transmembrane pressure and replacement fluid flow rate.
6. Method according to claims 1 to 3, in which said at least two parameters comprise blood pressure and blood flow rate.
7. Method according to claims 1 to 3, in which said at least two parameters comprise dialysate flow rate and dialysate temperature.
8. Method according to any of the proceeding claims, comprising the step of selecting an initial parameter to be controlled, if a switch from controlling said initial parameter to controlling another parameter has taken place, returning to said initial control parameter after a predetermined time span since said switch or when the initial control parameter has returned below its threshold or other predetermined value.
9. Method of controlling a dialysis apparatus for or comprising the steps of:
-causing the flow of blood on one side of a semi permeable membrane, -causing the flow of dialysate at the other side of said semi permeable membrane, -observing the transmembrane pressure, -observing the ultrafiltration flow rate, -defining a threshold value for the transmembrane pressure, -defining a threshold value for the ultrafiltration flow rate, -controlling either the transmembrane pressure or the ultrafiltration flow rate so as to maintain a predetermined value or follow a predetermined profile, switching from controlling transmembrane pressure to controlling ultrafiltration flow rate, when the ultrafiltration flow rate threshold is exceeded and switching from controlling ultrafiltrate flow rate to controlling transmembrane pressure when the transmembrane pressure threshold is exceeded.
10. Method of controlling a dialysis apparatus for or comprising the steps of:
-causing the flow of blood on one side of a semi permeable membrane, -causing the flow of dialysate at the other side of said semi permeable membrane, -providing replacement fluid at a certain rate, -observing the transmembrane pressure, -observing the replacement fluid rate, -defining a threshold value for the transmembrane pressure, -defining a threshold value for the replacement fluid rate, -controlling either the transmembrane pressure or the replacement fluid rate so as to maintain a predetermined value or follow a predetermined profile, switching from controlling transmembrane pressure to controlling replacement fluid rate, when the replacement fluid flow rate threshold is exceeded and switching from controlling replacement fluid flow rate to controlling transmembrane pressure when the transmembrane pressure threshold is exceeded.
11. Apparatus for hemodialysis, hemodiafiltration or hemofiltration comprising a dialysate flow path, a blood flow path, a dialyser having a semi permeable membrane, a fist compartment on one side of said semi permeable membrane coupled into said dialysate flow path and a second compartment on the other side of said membrane coupled in said blood flow path, means for measuring the transmembrane pressure, means for measuring the volume or flow rate of ultrafiltration liquid, means for regulating the transmembrane pressure, means for regulating the ultrafiltration flow rate, control means for selectively controlling either transmembrane pressure or ultrafiltration flow rate, means for setting and storing threshold values for transmembrane pressure and ultrafiltration flow rate, selection means for switching from controlling transmembrane pressure to controlling ultrafiltration flow rate, when the ultrafiltration flow rate threshold is exceeded and switching from controlling ultrafiltration flow rate to controlling transmembrane pressure when the transmembrane pressure threshold is exceeded.
12. Apparatus for hemodiafiltration or hemofiltration comprising a dialysate flow path, a blood flow path, a dialyser having a semi permeable membrane, a fist compartment on one side of said semi permeable membrane coupled into said dialysate flow path and a second compartment on the other side of said membrane coupled in said blood flow path, means for measuring the transmembrane pressure"
means for providing a replacement fluid flow at a certain flow rate, means for regulating the transmembrane pressure, means for regulating the replacement fluid flow rate, control means for selectively controlling either transmembrane pressure or replacement fluid flow rate, means for setting and storing threshold values for transmembrane pressure and replacement fluid flow rate, selection means for switching from controlling transmembrane pressure to controlling replacement fluid flow rate, when the replacement fluid flow rate threshold is exceeded and switching from controlling replacement fluid flow rate to controlling transmembrane pressure when the transmembrane pressure threshold is exceeded.
CA2460895A 2001-10-02 2002-10-01 Method of controlling a dialysis apparatus Expired - Lifetime CA2460895C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0103290-3 2001-10-02
SE0103290A SE523610C2 (en) 2001-10-02 2001-10-02 Method of controlling dialysis device
PCT/SE2002/001785 WO2003028860A1 (en) 2001-10-02 2002-10-01 Method of controlling a dialysis apparatus

Publications (2)

Publication Number Publication Date
CA2460895A1 true CA2460895A1 (en) 2003-04-10
CA2460895C CA2460895C (en) 2011-08-02

Family

ID=20285532

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2460895A Expired - Lifetime CA2460895C (en) 2001-10-02 2002-10-01 Method of controlling a dialysis apparatus

Country Status (10)

Country Link
US (1) US7494590B2 (en)
EP (1) EP1434646B2 (en)
JP (1) JP2005503903A (en)
KR (1) KR100878547B1 (en)
AT (1) ATE459408T1 (en)
CA (1) CA2460895C (en)
DE (1) DE60235561D1 (en)
ES (1) ES2341229T5 (en)
SE (1) SE523610C2 (en)
WO (1) WO2003028860A1 (en)

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Also Published As

Publication number Publication date
EP1434646B1 (en) 2010-03-03
DE60235561D1 (en) 2010-04-15
US7494590B2 (en) 2009-02-24
KR20040048913A (en) 2004-06-10
JP2005503903A (en) 2005-02-10
US20050061740A1 (en) 2005-03-24
ATE459408T1 (en) 2010-03-15
CA2460895C (en) 2011-08-02
ES2341229T5 (en) 2018-06-05
EP1434646B2 (en) 2018-04-18
WO2003028860A1 (en) 2003-04-10
EP1434646A1 (en) 2004-07-07
SE523610C2 (en) 2004-05-04
ES2341229T3 (en) 2010-06-17
SE0103290D0 (en) 2001-10-02
KR100878547B1 (en) 2009-01-14
SE0103290L (en) 2003-05-05

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