CA2460800A1 - Cardio-pulmonary monitoring device - Google Patents
Cardio-pulmonary monitoring device Download PDFInfo
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- CA2460800A1 CA2460800A1 CA002460800A CA2460800A CA2460800A1 CA 2460800 A1 CA2460800 A1 CA 2460800A1 CA 002460800 A CA002460800 A CA 002460800A CA 2460800 A CA2460800 A CA 2460800A CA 2460800 A1 CA2460800 A1 CA 2460800A1
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- breath
- heart sounds
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- sensors
- sounds
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B7/00—Instruments for auscultation
- A61B7/003—Detecting lung or respiration noise
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B7/00—Instruments for auscultation
- A61B7/02—Stethoscopes
- A61B7/04—Electric stethoscopes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0204—Acoustic sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/04—Arrangements of multiple sensors of the same type
- A61B2562/046—Arrangements of multiple sensors of the same type in a matrix array
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
Abstract
The present invention provides an apparatus for monitoring breath and heart sounds, the apparatus including, sensors for detecting breath and heart sounds, means for recording breath and heart sounds over time and a pattern classifier for comparing recorded breath and heart sounds with previously recorded breath and heart sounds.
Description
1 "Monitoring Device"
3 The present invention relates to an apparatus for 4 monitoring breath and heart sounds. In particular the apparatus allows continuous cardio-pulmonary 6 monitoring.
8 Monitoring of breath and heart sounds is used both 9 in diagnosis and as a means of determining the response of a patient to treatment.
12 Traditionally monitoring of breath and heart sounds 13 has been effected by a stethoscope. However, there 14 are many instances where the full use and capabilities of the traditional stethoscope are 16 restricted. In particular there may be problems 17 using the stethoscope when, access to the patient is 18 restricted, as in intensive care or operating 19 theatre situations. Also the nature of the patient's condition, for example extensive burns, 21 traumatic injury or obesity can restrict access.
22 Also, if the environment surrounding the patient is 23 noisy (e. g. in ambulances, helicopters, military CONFIRMATION COPY
1 vehicles, ships, disaster sites etc.) it may be 2 difficult to use a stethoscope effectively.
4 A further disadvantage of the traditional stethoscope is that it relies on the person using 6 the stethoscope having sensitive hearing across the 7 full frequency range. Interpretation of the sounds 8 produced by a traditional stethoscope relies on the 9 auditory performance of the user. As auditory performance often declines with age, older health 11 professionals using a traditional stethoscope can 12 find it more difficult to correctly interpret the 13 heart and breath sounds produced by a patient.
14 Furthermore, there may be important respiratory and cardiac sounds which are outside the normal auditory 16 range and therefore undetectable by "traditional"
17 stethoscopes.
19 Cardio-pulmonary monitoring of patients with time is important to determine the response of a patient to 21 treatment and in some cases the progress of disease.
22 Further, cardio-respiratory monitoring of patients 23 at risk from acute illness, including infants and 24 children at risk from Sudden Infant Death Syndrome (SIDS), may enable earlier treatment.
27 Monitoring of cardio-pulmonary function with time 28 using a traditional stethoscope requires that the 29 health professional is able to detect changes in the heart and breath sounds from individual measurements 31 at particular time points such as each hour, day, 32 week or longer. This relies on the ability of the 1 health professional to recall what a previous 2 measurement sounded like. In addition, if different 3 health professionals are monitoring a patient's 4 cardio-pulmonary function over a time period then the different interpretation of the sounds recorded 6 by each health professional via a stethoscope means 7 that subjective differences in the interpretation of 8 a patient's cardio-respiratory sounds must be taken 9 into account.
11 An object of the present invention is an improved 12 apparatus for monitoring breath and heart sounds.
14 Accordingly the present invention provides an apparatus comprising a device including at least two 16 sensors capable of being suitably positioned to 17 allow the capture of breath and heart sounds over a 18 period of time, means for recording the breath and 19 heart sounds and means to analyse the breath and heart sounds.
22 Suitably the sensors are non-invasive. They may be 23 either disposable or non-disposable. Any sensors 24 which can effectively capture the breath and heart sounds are appropriate ranging from simple 26 microphones to piezo-electric devices, ultrasound 27 devices and accelerometers. They must effectively 28 capture the breath and heart sounds when positioned 29 over the appropriate areas of the patient's chest.
31 Preferably the device of the present invention 32 comprises at least two sensors positioned such that 1 they are located on each side of the patient's 2 chest.
4 Preferably a plurality of sensors are suitably positioned for capturing breath and heart sounds by 6 locating the sensors in a matrix. The sensors must 7 be of suitable dimensions to be inserted into this 8 matrix.
Preferably this matrix forms a pad which can be used 11 to suitably locate the sensors by adhesive means.
13 Alternatively this matrix forms a pad which may be 14 worn or wrapped around a patient to suitably locate the sensors.
17 The matrix containing the sensors may be made of any 18 suitable material. Typically the matrix containing 19 the sensors is formed from foam, nylon or Gore-Tex material.
22 Preferably the pad comprises a number of layers.
24 Preferably the sensors are electronically connected to each other.
27 In one embodiment the signals produced by the 28 plurality of sensors are transferred to a monitor by 29 a single cable.
1 Alternatively the signals produced by the plurality 2 of sensors are transferred to a monitor by a 3 wireless interface.
8 Monitoring of breath and heart sounds is used both 9 in diagnosis and as a means of determining the response of a patient to treatment.
12 Traditionally monitoring of breath and heart sounds 13 has been effected by a stethoscope. However, there 14 are many instances where the full use and capabilities of the traditional stethoscope are 16 restricted. In particular there may be problems 17 using the stethoscope when, access to the patient is 18 restricted, as in intensive care or operating 19 theatre situations. Also the nature of the patient's condition, for example extensive burns, 21 traumatic injury or obesity can restrict access.
22 Also, if the environment surrounding the patient is 23 noisy (e. g. in ambulances, helicopters, military CONFIRMATION COPY
1 vehicles, ships, disaster sites etc.) it may be 2 difficult to use a stethoscope effectively.
4 A further disadvantage of the traditional stethoscope is that it relies on the person using 6 the stethoscope having sensitive hearing across the 7 full frequency range. Interpretation of the sounds 8 produced by a traditional stethoscope relies on the 9 auditory performance of the user. As auditory performance often declines with age, older health 11 professionals using a traditional stethoscope can 12 find it more difficult to correctly interpret the 13 heart and breath sounds produced by a patient.
14 Furthermore, there may be important respiratory and cardiac sounds which are outside the normal auditory 16 range and therefore undetectable by "traditional"
17 stethoscopes.
19 Cardio-pulmonary monitoring of patients with time is important to determine the response of a patient to 21 treatment and in some cases the progress of disease.
22 Further, cardio-respiratory monitoring of patients 23 at risk from acute illness, including infants and 24 children at risk from Sudden Infant Death Syndrome (SIDS), may enable earlier treatment.
27 Monitoring of cardio-pulmonary function with time 28 using a traditional stethoscope requires that the 29 health professional is able to detect changes in the heart and breath sounds from individual measurements 31 at particular time points such as each hour, day, 32 week or longer. This relies on the ability of the 1 health professional to recall what a previous 2 measurement sounded like. In addition, if different 3 health professionals are monitoring a patient's 4 cardio-pulmonary function over a time period then the different interpretation of the sounds recorded 6 by each health professional via a stethoscope means 7 that subjective differences in the interpretation of 8 a patient's cardio-respiratory sounds must be taken 9 into account.
11 An object of the present invention is an improved 12 apparatus for monitoring breath and heart sounds.
14 Accordingly the present invention provides an apparatus comprising a device including at least two 16 sensors capable of being suitably positioned to 17 allow the capture of breath and heart sounds over a 18 period of time, means for recording the breath and 19 heart sounds and means to analyse the breath and heart sounds.
22 Suitably the sensors are non-invasive. They may be 23 either disposable or non-disposable. Any sensors 24 which can effectively capture the breath and heart sounds are appropriate ranging from simple 26 microphones to piezo-electric devices, ultrasound 27 devices and accelerometers. They must effectively 28 capture the breath and heart sounds when positioned 29 over the appropriate areas of the patient's chest.
31 Preferably the device of the present invention 32 comprises at least two sensors positioned such that 1 they are located on each side of the patient's 2 chest.
4 Preferably a plurality of sensors are suitably positioned for capturing breath and heart sounds by 6 locating the sensors in a matrix. The sensors must 7 be of suitable dimensions to be inserted into this 8 matrix.
Preferably this matrix forms a pad which can be used 11 to suitably locate the sensors by adhesive means.
13 Alternatively this matrix forms a pad which may be 14 worn or wrapped around a patient to suitably locate the sensors.
17 The matrix containing the sensors may be made of any 18 suitable material. Typically the matrix containing 19 the sensors is formed from foam, nylon or Gore-Tex material.
22 Preferably the pad comprises a number of layers.
24 Preferably the sensors are electronically connected to each other.
27 In one embodiment the signals produced by the 28 plurality of sensors are transferred to a monitor by 29 a single cable.
1 Alternatively the signals produced by the plurality 2 of sensors are transferred to a monitor by a 3 wireless interface.
5 Preferably the matix containing the sensors can be 6 used remotely from the recording means and means to 7 analyse the breath and heart sounds.
9 Preferably the means for recording the heart and breath sounds can convert the breath and heart 11 sounds into an analogue signal 13 Preferably the means for recording the breath and 14 heart sounds can convert the heart and breath sounds into a digital signal.
17 Preferably the means to analyse the breath and heart 18 sounds includes means for determining the geometric 19 position in the body from which the breath and heart sounds originate.
22 Preferably the means to analyse the breath and heart 23 sounds can convert the breath and heart signal to a 24 graphical output that shows the position of particular sounds in relation to the lung and heart.
27 Preferably the means to analyse the breath and heart 28 sounds includes means for bandpass filtering the 29 signal in the range lOHz - 2kHz.
1 Preferably the means to analyse the breath and heart 2 sounds includes means for sub-band processing the 3 signal.
Preferably sub band processing of the signal uses 6 two sub-bands up to fn and from fn to an upper 7 frequency limit wherein fn is the anticipated upper 8 frequency limit of the normal range of sound from 9 the transducer site.
11 Preferably the means to analyse the breath and heart 12 sounds is capable of identifying the rate of 13 respiratory inhalation and exhalation phases.
Preferably the means to analyse the breath and heart 16 sounds includes a pattern classifier to enable the 17 signals recorded to be matched to previously 18 determined breath and heart signals.
Preferably the means to analyse the breath and heart 21 sounds uses short term spectral/parametric analysis 22 of respiratory phases in sub bands.
24 In one embodiment the sub bands are from lOHz to fn and fn to 2kHz.
27 The means to analyse the breath and heart sounds can 28 comprise a computer program.
The present invention thus provides a computer 31 program, preferably on a data carrier to a computer 32 readable medium having code or instructions for 2 a) receiving data from at least one sensor means 3 according to the present invention, 4 b) generating a pattern from the data of step (a), c) receiving data from predetermined patterns of 6 breath and heart sounds, 7 d) matching the pattern derived from step (b) with 8 the predetermined patterns of step (c), 9 e) displaying the match, 11 Preferably the device including the sensors to 12 detect breath and heart includes a global 13 positioning satellite locator.
Preferably the device including the senses to detect 16 breath and heart sounds includes further sensors for 17 monitoring the physiological state of the patient.
19 Examples of such sensors include, but are not limited to, temperature sensors, blood oxygen 21 sensors and other blood gas/chemical sensors.
23 According to a second aspect of the present 24 invention there is provided a method for interpreting breath and heart sounds comprising the 26 steps of, 27 (i) positioning of the device including the 28 sensors around the area of interest, 29 (ii) recording the breath and heart sounds over time, 31 (iii) converting the breath and heart sounds to a 32 signal in the range of lOHz-2kHz, 1 (iv) bandpass filtering the signal 2 (v) identifying the rate of respiratory 3 inhalation and exhalation phases 4 (vi) comparing the recorded signal data with known signal data of breath and heart 6 sounds, 7 (vii) determining if the signal data of breath and 8 heart sounds recorded matches known signal 9 data of breath and heart sounds.
11 Preferably the signal is digital.
13 Preferably step (iv) consists of performing 14 appropriate filtering and amplification of the signal.
17 Preferably the method includes the step of sub-18 processing the recorded signal.
More preferably the method includes the step of 21 mapping the signals to the heart and lung.
23 An embodiment of the present invention will now be 24 described, by way of example only, with reference to the accompanying drawings, 27 Figure 1 shows a front view of the device, 29 Figure 2 shows a side view of the device wherein the sensors are mounted in a matrix 31 which is conjoined to an outer layer on one 1 face and an adhesive layer on a second opposite 2 face, and 4 Figure 3 shows a block diagram of the automatic respiratory recognition system.
7 With reference to figure 1 an embodiment of the 8 present device is a pad comprising a plurality of 9 sensors, typically between six to twelve sensors.
11 A plurality of sensors may be positioned within each 12 region of the matrix pad with the intention being to 13 capture the strongest "signal" from that region.
14 The use of a plurality of sensors avoids the possibility of single sensor failure preventing 16 measurement of the breath and heart sounds. Thereby 17 accurate information may be relayed to the monitor.
19 The sensors are arrayed at particular locations in a matrix, the particular locations corresponding to 21 appropriate anatomical positions to enable the 22 continuous capture of breath and heart sounds.
24 The sensors will effectively "map" the lung and heart. Furthermore, the sensors in the device may 26 capture important respiratory and cardiac sounds 27 which are outside the normal auditory range and 28 therefore undetectable by "traditional"
29 stethoscopes.
31 The plurality of sensors will provide a complete 32 lung/heart map. As an example if all is well with 1 the patient the sensors will provide an all "green"
2 display and if there are specific diseased areas 3 "red" will be displayed within that region. There 4 will also be varying shades of colour between these 5 two ranges. It is also envisaged that a numerical 6 display will be provided. For example, a range of 7 0-100, with 0 being the worst and 100 being the 8 best. This may also be expressed as percent.
17 Preferably the means to analyse the breath and heart 18 sounds includes means for determining the geometric 19 position in the body from which the breath and heart sounds originate.
22 Preferably the means to analyse the breath and heart 23 sounds can convert the breath and heart signal to a 24 graphical output that shows the position of particular sounds in relation to the lung and heart.
27 Preferably the means to analyse the breath and heart 28 sounds includes means for bandpass filtering the 29 signal in the range lOHz - 2kHz.
1 Preferably the means to analyse the breath and heart 2 sounds includes means for sub-band processing the 3 signal.
Preferably sub band processing of the signal uses 6 two sub-bands up to fn and from fn to an upper 7 frequency limit wherein fn is the anticipated upper 8 frequency limit of the normal range of sound from 9 the transducer site.
11 Preferably the means to analyse the breath and heart 12 sounds is capable of identifying the rate of 13 respiratory inhalation and exhalation phases.
Preferably the means to analyse the breath and heart 16 sounds includes a pattern classifier to enable the 17 signals recorded to be matched to previously 18 determined breath and heart signals.
Preferably the means to analyse the breath and heart 21 sounds uses short term spectral/parametric analysis 22 of respiratory phases in sub bands.
24 In one embodiment the sub bands are from lOHz to fn and fn to 2kHz.
27 The means to analyse the breath and heart sounds can 28 comprise a computer program.
The present invention thus provides a computer 31 program, preferably on a data carrier to a computer 32 readable medium having code or instructions for 2 a) receiving data from at least one sensor means 3 according to the present invention, 4 b) generating a pattern from the data of step (a), c) receiving data from predetermined patterns of 6 breath and heart sounds, 7 d) matching the pattern derived from step (b) with 8 the predetermined patterns of step (c), 9 e) displaying the match, 11 Preferably the device including the sensors to 12 detect breath and heart includes a global 13 positioning satellite locator.
Preferably the device including the senses to detect 16 breath and heart sounds includes further sensors for 17 monitoring the physiological state of the patient.
19 Examples of such sensors include, but are not limited to, temperature sensors, blood oxygen 21 sensors and other blood gas/chemical sensors.
23 According to a second aspect of the present 24 invention there is provided a method for interpreting breath and heart sounds comprising the 26 steps of, 27 (i) positioning of the device including the 28 sensors around the area of interest, 29 (ii) recording the breath and heart sounds over time, 31 (iii) converting the breath and heart sounds to a 32 signal in the range of lOHz-2kHz, 1 (iv) bandpass filtering the signal 2 (v) identifying the rate of respiratory 3 inhalation and exhalation phases 4 (vi) comparing the recorded signal data with known signal data of breath and heart 6 sounds, 7 (vii) determining if the signal data of breath and 8 heart sounds recorded matches known signal 9 data of breath and heart sounds.
11 Preferably the signal is digital.
13 Preferably step (iv) consists of performing 14 appropriate filtering and amplification of the signal.
17 Preferably the method includes the step of sub-18 processing the recorded signal.
More preferably the method includes the step of 21 mapping the signals to the heart and lung.
23 An embodiment of the present invention will now be 24 described, by way of example only, with reference to the accompanying drawings, 27 Figure 1 shows a front view of the device, 29 Figure 2 shows a side view of the device wherein the sensors are mounted in a matrix 31 which is conjoined to an outer layer on one 1 face and an adhesive layer on a second opposite 2 face, and 4 Figure 3 shows a block diagram of the automatic respiratory recognition system.
7 With reference to figure 1 an embodiment of the 8 present device is a pad comprising a plurality of 9 sensors, typically between six to twelve sensors.
11 A plurality of sensors may be positioned within each 12 region of the matrix pad with the intention being to 13 capture the strongest "signal" from that region.
14 The use of a plurality of sensors avoids the possibility of single sensor failure preventing 16 measurement of the breath and heart sounds. Thereby 17 accurate information may be relayed to the monitor.
19 The sensors are arrayed at particular locations in a matrix, the particular locations corresponding to 21 appropriate anatomical positions to enable the 22 continuous capture of breath and heart sounds.
24 The sensors will effectively "map" the lung and heart. Furthermore, the sensors in the device may 26 capture important respiratory and cardiac sounds 27 which are outside the normal auditory range and 28 therefore undetectable by "traditional"
29 stethoscopes.
31 The plurality of sensors will provide a complete 32 lung/heart map. As an example if all is well with 1 the patient the sensors will provide an all "green"
2 display and if there are specific diseased areas 3 "red" will be displayed within that region. There 4 will also be varying shades of colour between these 5 two ranges. It is also envisaged that a numerical 6 display will be provided. For example, a range of 7 0-100, with 0 being the worst and 100 being the 8 best. This may also be expressed as percent.
10 The pad comprising the matrix in which the sensors 11 are arrayed is typically between 20 cm x 30 cm, 12 however the size is dependent on the anatomical 13 proportions of the patient. It can be envisaged 14 that the size of the pad and the location of the sensors may be varied to suit babies or children.
17 The individual sensors are electronically connected 18 such that the signals produced by each sensor can be 19 transferred to a monitor by a single lead. The monitor enables the amplification, analysis and 21 display of the signals produced by the sensors in 22 both analogue and digital format.
24 With reference to figure 2 the pad is comprised of multiple layers wherein a foam material layer houses 26 the sensors. The foam material layer is attached to 27 a first layer.on one face and a second backing layer 28 on the opposite face.
The first layer has an adhesive face, opposite the 31 face of the first layer attached to the foam 32 material layer, for fixing the pad to the patient 1 and locating the sensors to suitable anatomical 2 positions. The adhesive face of this first layer is 3 protected by a peel off protective seal, which 4 remains in place until the pad is to be positioned on to the patient. The adhesive used in the 6 adhesive portion is preferably hypoallergenic, 7 comfortable and sufficiently adherent to allow 2-5 8 days of continuous placement of the pad.
Between the first layer (in contact with the skin) 11 and the second layer (containing the sensors) it is 12 desirable to have an intermediate "space" or 13 "vacuum" to facilitate and improve sound 14 transmission from the chest to the sensors.
16 The second backing layer is attached to the foam 17 material layer on the face opposite to that which is 18 attached to the first layer. This second backing 19 layer is thus the furthest from the patient when the pad is positioned on the patient in use. This 21 second backing layer provides strength and 22 robustness to the pad. Further, the second backing 23 layer allows attachment of a lead to the pad for 24 transfer of the signals produced by the sensors to a monitor.
27 Each sensor in the pad is electronically linked to a 28 common lead for transfer of the signals produced by 29 the sensors to a monitor.
31 Following the transfer of signals from each of the 32 sensors by the common cable they are amplified, 1 analysed and displayed in both analogue and digital 2 format.
4 An alternative embodiment of the present invention is also provided wherein the device containing the 6 sensors is not linked to a monitor by a cable, but 7 by a wireless interface system. This wireless 8 interface system allows remote or distant monitoring 9 of the cardio-pulmonary signals.
11 Using the wireless interface, information can be 12 relayed from the patient to a health professional 13 without the need for the patient to be near a 14 monitor or connected to any equipment other than the sensor containing device.
17 By suitable positioning of the pad incorporating the 18 wireless.interface onto the patient the cardio-19 pulmonary function of the patient may be monitored.
This allows monitoring of patients' cardio-pulmonary 21 function from their own homes, remote locations, or 22 in situations where monitors are not be available, 23 for instance in planes or at sea.
The apparatus can be used to effect the automatic 26 recognition of respiratory sounds.
28 Respiratory sounds (normal and abnormal) have a 29 typical frequency range of 100-2000Hz and a dynamic range of some 50-60dB. The upper extent of the 31 frequency range is dependent upon the point at which 32 the sound is transduced. The sound is effectively 1 low-pass filtered by the body tissue between the 2 lungs and the transducer, with the cut-off frequency 3 of the low-pass fiiltering being dependent of the 4 transducer site.
6 For digital processing, respiratroy signals should 7 be sampled with a minimum sampling frequency of 4kHz 8 at a minimum of 8 bits / sample. However, in system 9 and algorithm development stages, a sampling frequeny of at least 8 khz at 16 bits / sample is 11 recommended.
13 As shown in the block diagram of figure 3 of the 14 automatic respiratory recognition system the objective is to automatically determine whether the 16 input acoustic pattern is normal / abnormal and, if 17 abnormal which pathological condition is determined.
19 The front end analysis involved in the canonic automatic respiratory recognition system is 22 (1) Bandpass filtering the signal in the range 23 lOHz-2kHz, (2) Sub-band processing of the signal using two 26 sub-bands - 10 to fn and fn to 2kHz, where fn 27 is the anticipated upper frequency limit of the 28 normal range of sound from the transducer site, (3) Identification and rate of respiratory 31 inhalation and exhalation phases, 1 (4) Short-term spectral / parametric analysis of 2 respiratory phases in both sub-bands, 4 The pattern classifier comprises pattern matching against stored respiratory patterns (based on 6 possible spectral, energy or parametric information) 7 and a decision rule, which may be linear or 8 nonlinear. The pattern classifier can be either a 9 standard statistical classifier or a classifier based on artificial intelligence techniques, such as 11 neural networks or fuzzy logic classifiers.
13 In use the recorded sounds are transmitted to the 14 analysis means are band pass filtered and sub-band pass filtered.
17 The recorded sounds also include sounds which are 18 detected and then analysed in real time.
The filtered data is then compared against 21 previously determined data using the pattern 22 classifier.
24 The previously determined data can be from the same or different patient and may comprise a description 26 indicating if the predetermined data is indicative 27 of normal of abnormal breath and heart sounds.
29 The newly recorded data can thus be compared against the predetermined data and assigned as normal or 31 abnormal. Further comparison of the recorded data 32 signal with abnormal data might allow a match 1 against a similar previously determined pattern, and 2 such a match may allow a diagnosis of the 3 abnormality and possibly the disease promoting the 4 abnormality to be made by the analysis means.
6 A global positioning satellite locator (GPS) or 7 further sensors enabling monitoring of the patient 8 may also be incorporated into the pad of the device 9 and the information from the GPS locator or 10 alternative sensor relayed to the monitor by the 11 wireless interface means.
13 It can be envisaged that the device may be suitably 14 positioned to the patient by alternative means than 15 adhesive.
17 The individual sensors are electronically connected 18 such that the signals produced by each sensor can be 19 transferred to a monitor by a single lead. The monitor enables the amplification, analysis and 21 display of the signals produced by the sensors in 22 both analogue and digital format.
24 With reference to figure 2 the pad is comprised of multiple layers wherein a foam material layer houses 26 the sensors. The foam material layer is attached to 27 a first layer.on one face and a second backing layer 28 on the opposite face.
The first layer has an adhesive face, opposite the 31 face of the first layer attached to the foam 32 material layer, for fixing the pad to the patient 1 and locating the sensors to suitable anatomical 2 positions. The adhesive face of this first layer is 3 protected by a peel off protective seal, which 4 remains in place until the pad is to be positioned on to the patient. The adhesive used in the 6 adhesive portion is preferably hypoallergenic, 7 comfortable and sufficiently adherent to allow 2-5 8 days of continuous placement of the pad.
Between the first layer (in contact with the skin) 11 and the second layer (containing the sensors) it is 12 desirable to have an intermediate "space" or 13 "vacuum" to facilitate and improve sound 14 transmission from the chest to the sensors.
16 The second backing layer is attached to the foam 17 material layer on the face opposite to that which is 18 attached to the first layer. This second backing 19 layer is thus the furthest from the patient when the pad is positioned on the patient in use. This 21 second backing layer provides strength and 22 robustness to the pad. Further, the second backing 23 layer allows attachment of a lead to the pad for 24 transfer of the signals produced by the sensors to a monitor.
27 Each sensor in the pad is electronically linked to a 28 common lead for transfer of the signals produced by 29 the sensors to a monitor.
31 Following the transfer of signals from each of the 32 sensors by the common cable they are amplified, 1 analysed and displayed in both analogue and digital 2 format.
4 An alternative embodiment of the present invention is also provided wherein the device containing the 6 sensors is not linked to a monitor by a cable, but 7 by a wireless interface system. This wireless 8 interface system allows remote or distant monitoring 9 of the cardio-pulmonary signals.
11 Using the wireless interface, information can be 12 relayed from the patient to a health professional 13 without the need for the patient to be near a 14 monitor or connected to any equipment other than the sensor containing device.
17 By suitable positioning of the pad incorporating the 18 wireless.interface onto the patient the cardio-19 pulmonary function of the patient may be monitored.
This allows monitoring of patients' cardio-pulmonary 21 function from their own homes, remote locations, or 22 in situations where monitors are not be available, 23 for instance in planes or at sea.
The apparatus can be used to effect the automatic 26 recognition of respiratory sounds.
28 Respiratory sounds (normal and abnormal) have a 29 typical frequency range of 100-2000Hz and a dynamic range of some 50-60dB. The upper extent of the 31 frequency range is dependent upon the point at which 32 the sound is transduced. The sound is effectively 1 low-pass filtered by the body tissue between the 2 lungs and the transducer, with the cut-off frequency 3 of the low-pass fiiltering being dependent of the 4 transducer site.
6 For digital processing, respiratroy signals should 7 be sampled with a minimum sampling frequency of 4kHz 8 at a minimum of 8 bits / sample. However, in system 9 and algorithm development stages, a sampling frequeny of at least 8 khz at 16 bits / sample is 11 recommended.
13 As shown in the block diagram of figure 3 of the 14 automatic respiratory recognition system the objective is to automatically determine whether the 16 input acoustic pattern is normal / abnormal and, if 17 abnormal which pathological condition is determined.
19 The front end analysis involved in the canonic automatic respiratory recognition system is 22 (1) Bandpass filtering the signal in the range 23 lOHz-2kHz, (2) Sub-band processing of the signal using two 26 sub-bands - 10 to fn and fn to 2kHz, where fn 27 is the anticipated upper frequency limit of the 28 normal range of sound from the transducer site, (3) Identification and rate of respiratory 31 inhalation and exhalation phases, 1 (4) Short-term spectral / parametric analysis of 2 respiratory phases in both sub-bands, 4 The pattern classifier comprises pattern matching against stored respiratory patterns (based on 6 possible spectral, energy or parametric information) 7 and a decision rule, which may be linear or 8 nonlinear. The pattern classifier can be either a 9 standard statistical classifier or a classifier based on artificial intelligence techniques, such as 11 neural networks or fuzzy logic classifiers.
13 In use the recorded sounds are transmitted to the 14 analysis means are band pass filtered and sub-band pass filtered.
17 The recorded sounds also include sounds which are 18 detected and then analysed in real time.
The filtered data is then compared against 21 previously determined data using the pattern 22 classifier.
24 The previously determined data can be from the same or different patient and may comprise a description 26 indicating if the predetermined data is indicative 27 of normal of abnormal breath and heart sounds.
29 The newly recorded data can thus be compared against the predetermined data and assigned as normal or 31 abnormal. Further comparison of the recorded data 32 signal with abnormal data might allow a match 1 against a similar previously determined pattern, and 2 such a match may allow a diagnosis of the 3 abnormality and possibly the disease promoting the 4 abnormality to be made by the analysis means.
6 A global positioning satellite locator (GPS) or 7 further sensors enabling monitoring of the patient 8 may also be incorporated into the pad of the device 9 and the information from the GPS locator or 10 alternative sensor relayed to the monitor by the 11 wireless interface means.
13 It can be envisaged that the device may be suitably 14 positioned to the patient by alternative means than 15 adhesive.
17 The sensors may be incorporated into a pad which can 18 be wrapped around the patient or worn by the patient 19 to allow positioning of the sensors at suitable anatomical positions.
22 Alternatively the sensors may be incorporated with 23 alternative fixing means such as suction cups to 24 allow their accurate placement onto the patient.
26 The present invention has a number of advantages.
27 It may be used to continuously monitor a patient's 28 cardio-pulmonary function. This is advantageous 29 over traditional stethoscopes, which can only record a patient's cardio-pulmonary function at distinct 31 time points.
1 As the device allows the non-subjective monitoring 2 of a patient's cardio-pulmonary function over time, 3 differences in the interpretation of cardio-4 pulmonary sounds by different health professionals do not have to be taken into account when monitoring 6 the patient.
8 The device is primarily designed for monitoring 9 breath and heart sounds over the patient's chest, however it could easily be adapted for foetal 11 monitoring either throughout pregnancy or during 12 labour. Similarly, if a woman requires anaethesia/
13 surgery / intensive care during her pregnancy it is 14 not inconceivable that one device could be used to monitor the mother and another to monitor the 16 foetus.
18 In use the device, which includes in the sensors is 19 a pad which can be wrapped around the patient, the pad is then suitably positioned around the patient 21 chest such that breath and heart sounds can be 22 measured. Due to the plurality of the sensors the 23 exact positioning of the pad is not crucial as 24 typically if placed in a generally correct position, breath and heart sounds will be detected and 26 recorded.
28 The pad is kept in position for a period of time 29 suitable to allow data collection, this may be minutes, hours or days as required to allow breath 31 and heart sounds to be suitably recorded.
1 The breath and heart sounds are transmitted to 2 recording means to record the sounds.
3 Transmission may occur via wires linking the device 4 to the recording and analysis means of via a wireless system.
7 Further usage and development of the device could be 8 in the field of veterinary obstetrics and veterinary 9 medicine with regard to both large and small animals that are pregnant/about foal, calf etc. or need 11 anaesthesia and surgery.
13 The device will further provide clear and effective 14 training for students of medicine and nursing, as it will allow the unambiguous interpretation of normal 16 and pathological heart and breath sounds.
18 The device is robust, easily stored and not easily 19 damaged. The entire device or any part thereof may also be disposable.
22 It maybe used in daylight or in the dark which is 23 useful in military situations or for use in dark 24 rooms.
26 As there is an equal distribution of sensors between 27 the left and right sides of the chest, differential 28 interpretation of normal and abnormal breath sounds 29 will be possible.
1 The device will allow diagnosis or determination of 2 a patient's response to treatment to be performed by 3 a suitable health professional from a distance.
This distant or remote monitoring of a patient's 6 cardio-pulmonary function has particular importance 7 in cases where patients are in planes, ambulances, 8 helicopters or remote situations.
22 Alternatively the sensors may be incorporated with 23 alternative fixing means such as suction cups to 24 allow their accurate placement onto the patient.
26 The present invention has a number of advantages.
27 It may be used to continuously monitor a patient's 28 cardio-pulmonary function. This is advantageous 29 over traditional stethoscopes, which can only record a patient's cardio-pulmonary function at distinct 31 time points.
1 As the device allows the non-subjective monitoring 2 of a patient's cardio-pulmonary function over time, 3 differences in the interpretation of cardio-4 pulmonary sounds by different health professionals do not have to be taken into account when monitoring 6 the patient.
8 The device is primarily designed for monitoring 9 breath and heart sounds over the patient's chest, however it could easily be adapted for foetal 11 monitoring either throughout pregnancy or during 12 labour. Similarly, if a woman requires anaethesia/
13 surgery / intensive care during her pregnancy it is 14 not inconceivable that one device could be used to monitor the mother and another to monitor the 16 foetus.
18 In use the device, which includes in the sensors is 19 a pad which can be wrapped around the patient, the pad is then suitably positioned around the patient 21 chest such that breath and heart sounds can be 22 measured. Due to the plurality of the sensors the 23 exact positioning of the pad is not crucial as 24 typically if placed in a generally correct position, breath and heart sounds will be detected and 26 recorded.
28 The pad is kept in position for a period of time 29 suitable to allow data collection, this may be minutes, hours or days as required to allow breath 31 and heart sounds to be suitably recorded.
1 The breath and heart sounds are transmitted to 2 recording means to record the sounds.
3 Transmission may occur via wires linking the device 4 to the recording and analysis means of via a wireless system.
7 Further usage and development of the device could be 8 in the field of veterinary obstetrics and veterinary 9 medicine with regard to both large and small animals that are pregnant/about foal, calf etc. or need 11 anaesthesia and surgery.
13 The device will further provide clear and effective 14 training for students of medicine and nursing, as it will allow the unambiguous interpretation of normal 16 and pathological heart and breath sounds.
18 The device is robust, easily stored and not easily 19 damaged. The entire device or any part thereof may also be disposable.
22 It maybe used in daylight or in the dark which is 23 useful in military situations or for use in dark 24 rooms.
26 As there is an equal distribution of sensors between 27 the left and right sides of the chest, differential 28 interpretation of normal and abnormal breath sounds 29 will be possible.
1 The device will allow diagnosis or determination of 2 a patient's response to treatment to be performed by 3 a suitable health professional from a distance.
This distant or remote monitoring of a patient's 6 cardio-pulmonary function has particular importance 7 in cases where patients are in planes, ambulances, 8 helicopters or remote situations.
Claims (23)
1. An apparatus comprising a device including at least two sound sensors embedded at different locations in a pad capable of attachment to the skin of a patient, the sensors being suitably positioned in the pad to allow the capture of breath and heart sounds over a period of time, means for recording the heart and breath sounds, and means to analyze the heart and breath sounds.
2. An apparatus as claimed in claim 1 wherein the device comprises at least two sensors positioned such that they are located on each side of the patient's chest.
3. An apparatus as claimed in claim 1 wherein a plurality of sensors are suitability positioned for capturing breath and heart sounds by locating the sensors in a matrix.
4. An apparatus as claimed in claim 1, 2 or 3 wherein the pad is attachable to the patient's skin by adhesive means.
5. An apparatus as claimed in any preceding claim, wherein the pad may be worn or wrapped around a patient to suitability locate the sensors.
6. An apparatus as claimed in any preceding claim wherein the sensors are electronically connected to each other.
7. An apparatus as claimed in any preceding claim wherein the signals produced by the plurality of sensors are transferred to a monitor by a single cable.
8. An apparatus as claimed in any preceding claim wherein the sensors can be used remotely from the recording means and means to analyse the breath and heart sounds.
9. An apparatus as claimed in any preceding claim wherein the means for recording the breath and heart sounds can convert the breath and heart sounds into an analogue signal.
10. An apparatus as claimed in claims 1 to 8 wherein the means for recording the breath and heart sounds can convert the breath and heart sounds into a digital signal.
11. An apparatus as claimed in any preceding claim wherein the means to analyze the breath and heart sounds includes means for determining the geometric position in the body from which the breath and heart sounds originate.
12. An apparatus as claimed in any preceding claim wherein the means to analyze the breath and heart sounds can convert the breath and heart signal to a graphical output that shows the position of particular sounds in relation to the lung and heart.
13. An apparatus as claimed in any preceding claim wherein the means to analyze the breath and heart sounds includes means for bandpass filtering the signal in the range 10Hz to an upper frequency limit.
14. An apparatus as claimed in any preceding claim wherein the means to analyze the breath and heart sounds includes means for sub-band processing the signal.
15. An apparatus as claimed in claim wherein sub-band processing of the signal uses two sub-bands 10Hz to fn and from fn to an upper frequency limit wherein fn is the anticipated upper frequency limit of the normal range of 17 sound from the transducer site.
16. An apparatus as claimed in any preceding claim wherein the means to analyze the breath and heart sounds is capable of identifying the rate of respiratory inhalation and exhalation phases.
17. An apparatus as claimed in any preceding claim wherein the means to analyze the breath and heart sounds includes a pattern classifier to enable the signals recorded to be matched to previously determined breath and heart signals.
18. An apparatus as claimed in any preceding claim wherein the means to analyze the breath and heart sounds uses short term spectral/parametric analysis.
19. An apparatus as claimed in any preceding claim including a global positioning satellite locator.
20. An apparatus as claimed in any preceding claim including additional sensors for monitoring the physiological state of the patient.
21. A method for interpreting breath and heart sounds using the apparatus of claim 1, comprising the steps of:
i) positioning the device including the sensors around the area of interest, ii) recording the breath and heart sounds over time, iii) converting the breath and heart sounds to a signal in the range of 10Hz to an upper frequency limit, iv) bandpass filtering the signal v) identifying the rate of respiratoryinhalation and exhalation phases vi ) comparing the recorded signal data with known signal data of breath and heart sounds, vii) determining if the signal data of breath and heart sounds recorded matches known signal data of breath and heart sounds,
i) positioning the device including the sensors around the area of interest, ii) recording the breath and heart sounds over time, iii) converting the breath and heart sounds to a signal in the range of 10Hz to an upper frequency limit, iv) bandpass filtering the signal v) identifying the rate of respiratoryinhalation and exhalation phases vi ) comparing the recorded signal data with known signal data of breath and heart sounds, vii) determining if the signal data of breath and heart sounds recorded matches known signal data of breath and heart sounds,
22. A method as claimed in claim 21 including the step of sub-processing the recorded signal.
23. A method as claimed in claim 21 or 22 including the step of mapping the signals to the heart and lung.
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GB0118728.5 | 2001-07-31 | ||
PCT/GB2002/003526 WO2003011132A2 (en) | 2001-07-31 | 2002-07-31 | Cardio-pulmonary monitoring device |
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CA002460800A Abandoned CA2460800A1 (en) | 2001-07-31 | 2002-07-31 | Cardio-pulmonary monitoring device |
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EP (1) | EP1416847B1 (en) |
AT (1) | ATE356576T1 (en) |
AU (1) | AU2002330593B2 (en) |
CA (1) | CA2460800A1 (en) |
DE (1) | DE60218863T2 (en) |
GB (1) | GB0118728D0 (en) |
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US7585279B2 (en) | 2005-07-26 | 2009-09-08 | Cardiac Pacemakers, Inc. | Managing preload reserve by tracking the ventricular operating point with heart sounds |
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WO2003011132A2 (en) | 2003-02-13 |
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EP1416847A2 (en) | 2004-05-12 |
AU2002330593B2 (en) | 2008-07-31 |
GB0118728D0 (en) | 2001-09-26 |
EP1416847B1 (en) | 2007-03-14 |
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