CA2442517A1 - Syringe for visco-elastic solutions - Google Patents

Syringe for visco-elastic solutions Download PDF

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Publication number
CA2442517A1
CA2442517A1 CA002442517A CA2442517A CA2442517A1 CA 2442517 A1 CA2442517 A1 CA 2442517A1 CA 002442517 A CA002442517 A CA 002442517A CA 2442517 A CA2442517 A CA 2442517A CA 2442517 A1 CA2442517 A1 CA 2442517A1
Authority
CA
Canada
Prior art keywords
diaphragm
viscoelastic
solutions
syringe
different
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002442517A
Other languages
French (fr)
Other versions
CA2442517C (en
Inventor
Patrice Vincent
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LABORATOIRE DE CONTACTOLOGIE APPLIQUEE - LCA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2442517A1 publication Critical patent/CA2442517A1/en
Application granted granted Critical
Publication of CA2442517C publication Critical patent/CA2442517C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
    • A61M5/286—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/284—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M2005/1787—Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid

Abstract

The invention concerns a device for dispensing visco-elastic solutions consisting of a syringe (1) which contains at least two visco-elastic solutions (V1, V2) having different properties, said solutions (V1, V2) being dispensed successively, in a predetermined sequence. The invention is characterised in that said syringe (1) comprises at least a mobile diaphragm (10), separating said at least two visco-elastic solutions (V1, V2).

Claims (8)

1. A device for dispensing viscoelastic solutions, said device consisting of a syringe (1) which contains at least two viscoelastic solutions (V1, V2) having different properties, said solutions (V1, V2) being dispensed in succession, in a predetermined order, said syringe (1) including at least one moving diaphragm (10) that separates said at least two viscoelastic solutions (V1, V2), the device being characterized in that said moving diaphragm (10) incorporates a preferably small opening (11) enabling the viscoelastic solution (V2) disposed upstream from the diaphragm (10) to be discharged after the viscoelastic solution (V1) disposed downstream from the diaphragm (10) has been dispensed in full.
2. A device according to claim 1, in which said diaphragm (10) includes sealing gaskets (15).
3. A device according to claim 1 or claim 2, in which a small air bubble is disposed in said opening (11) in the diaphragm (10) so as to prevent any contact between the viscoelastic solutions (V1, V2).
4. A device according to any preceding claim, in which said diaphragm (10) is connected via a temporary mechanical coupling to the plunger (4) of the syringe during dispensing of the viscoelastic solution (V1) disposed downstream from the diaphragm (10), said temporary mechanical coupling being eliminated once said viscoelastic solution (VI) has been dispensed in full, so as to enable the viscoelastic solution (V2) disposed upstream from the diaphragm (10) to be dispensed.
5. A device according to any preceding claim, in which said at least two viscoelastic solutions (V1, V2) have different rheological properties.
6. A device according to any preceding claim, in which said at least two viscoelastic solutions (V1, V2) have different chemical compositions and/or different molecular weights of their active principles and/or different concentrations of their active principles.
7. A device according to any preceding claim, in which said at least two viscoelastic solutions have dynamic viscosities that are different at high shear rates.
8. The use of the device according to any preceding claim in cataract surgery.
CA2442517A 2001-03-27 2002-03-26 Syringe for visco-elastic solutions Expired - Lifetime CA2442517C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR01/04090 2001-03-27
FR0104090A FR2822710B1 (en) 2001-03-27 2001-03-27 SYRINGE FOR VISCOLEASTIC SOLUTIONS
PCT/FR2002/001035 WO2002076534A1 (en) 2001-03-27 2002-03-26 Syringe for visco-elastic solutions

Publications (2)

Publication Number Publication Date
CA2442517A1 true CA2442517A1 (en) 2002-10-03
CA2442517C CA2442517C (en) 2010-06-15

Family

ID=8861572

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2442517A Expired - Lifetime CA2442517C (en) 2001-03-27 2002-03-26 Syringe for visco-elastic solutions

Country Status (11)

Country Link
US (1) US7001362B2 (en)
EP (1) EP1372766B1 (en)
JP (1) JP2004538043A (en)
AT (1) ATE458515T1 (en)
CA (1) CA2442517C (en)
DE (1) DE60235450D1 (en)
DK (1) DK1372766T3 (en)
ES (1) ES2338993T3 (en)
FR (1) FR2822710B1 (en)
PT (1) PT1372766E (en)
WO (1) WO2002076534A1 (en)

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FR2822710B1 (en) * 2001-03-27 2004-04-02 Lab Contactologie Appl Lca SYRINGE FOR VISCOLEASTIC SOLUTIONS
NZ548748A (en) * 2004-02-02 2010-09-30 Bimeda Res & Dev Ltd Method and device for treating a teat canal of an animal
GB2429159C (en) 2004-02-02 2016-07-06 Bimeda Res & Dev Ltd Method and device for treating a teat canal of an animal
US7101354B2 (en) * 2004-05-03 2006-09-05 Infusive Technologies, Llc Mixing syringe with and without flush
US6997910B2 (en) * 2004-05-03 2006-02-14 Infusive Technologies, Llc Multi-chamber, sequential dose dispensing syringe
US7998106B2 (en) * 2004-05-03 2011-08-16 Thorne Jr Gale H Safety dispensing system for hazardous substances
EP1827326A4 (en) * 2004-12-10 2010-01-06 Saebo Inc Dynamic hand splints
US8529517B2 (en) * 2005-05-02 2013-09-10 Shi Zi Technology, Ltd. Autoflush syringe
US8075533B2 (en) 2005-05-02 2011-12-13 Preventiv, Inc. Autoflush syringe
US8936577B2 (en) 2005-05-02 2015-01-20 Shi Zi Technology, Ltd. Methods and devices for autoflush syringes
AU2008207828B2 (en) 2007-01-25 2013-09-19 Hyperbranch Medical Technology, Inc. Applicators for multiple component formulations and the like, and methods of use thereof
JP2008259704A (en) * 2007-04-12 2008-10-30 Hisamitsu Pharmaceut Co Inc Prefilled syringe
CA2639729A1 (en) * 2007-09-27 2009-03-27 Tyco Healthcare Group Lp Multiple stage fluid delivery device and method of use
US8142403B2 (en) * 2008-06-30 2012-03-27 Tyco Healthcare Group Lp Syringe assembly with plunger having a secondary dispensing reservoir
US8152778B2 (en) * 2008-09-30 2012-04-10 Tyco Healthcare Group Lp Device for interfacing with standard luer lock syringes
EP2593769B2 (en) * 2010-07-14 2023-08-30 Qiagen GmbH New liquid processing device
CA2851521C (en) 2011-10-14 2020-09-22 Amgen Inc. Injector and method of assembly
DE102012107652A1 (en) * 2012-08-21 2014-03-20 Astrium Gmbh Container for the at least largely separate storage and delivery of substances, in particular for storage and delivery in outer space
US10195344B2 (en) * 2012-11-26 2019-02-05 Becton, Dickinson And Company Valve permitting mixing in a drug delivery device
AU2014238267B2 (en) * 2013-03-22 2019-08-15 Amgen Inc. Injector and method of assembly
JP6514211B2 (en) 2013-09-16 2019-05-15 ゾエティス・サービシーズ・エルエルシー Assembly and related methods for continuous drug delivery
CA2920894C (en) 2013-10-24 2023-03-14 Amgen Inc. Injector and method of assembly
US10952709B2 (en) 2014-04-04 2021-03-23 Hyperbranch Medical Technology, Inc. Extended tip spray applicator for two-component surgical sealant, and methods of use thereof
US9867952B2 (en) 2014-10-07 2018-01-16 N&M Surgical Advancements, LLC Delivery tool of a viscoelastic syringe assembly
US10258986B2 (en) 2014-11-12 2019-04-16 University Of New Hampshire Viscoelastic fluid drop production
DE102015002234A1 (en) 2014-12-05 2016-06-09 Elm - Plastic Gmbh Injector for dispensing a liquid or pasty substance, in particular medicament
DE102015206757A1 (en) * 2015-04-15 2016-10-20 Henkel IP & Holding GmbH Mixing and dispensing device and method for the provision and application of an adhesive consisting of at least two components
US10124340B2 (en) * 2015-12-08 2018-11-13 Electronics And Telecommunications Research Institute Reagent storage device and bio-reaction apparatus including the same
KR102055917B1 (en) * 2015-12-08 2019-12-16 한국전자통신연구원 Device for storing reagents and apparatus for bio-reaction having the same
US20220134003A1 (en) 2019-02-27 2022-05-05 Becton Dickinson France Valve Stopper for a Medical Injection Device and Medical Injection Device for Injecting at Least One Composition
WO2021013752A1 (en) * 2019-07-19 2021-01-28 Septodont Ou Septodont Sas Ou Specialites Septodont Cartridge for dispensing a material
EP3881877A1 (en) 2020-03-17 2021-09-22 Becton Dickinson France Stopper for a medical injection device

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Also Published As

Publication number Publication date
ATE458515T1 (en) 2010-03-15
FR2822710A1 (en) 2002-10-04
ES2338993T3 (en) 2010-05-14
JP2004538043A (en) 2004-12-24
EP1372766B1 (en) 2010-02-24
CA2442517C (en) 2010-06-15
DK1372766T3 (en) 2010-05-25
DE60235450D1 (en) 2010-04-08
WO2002076534A1 (en) 2002-10-03
FR2822710B1 (en) 2004-04-02
US7001362B2 (en) 2006-02-21
US20040116871A1 (en) 2004-06-17
EP1372766A1 (en) 2004-01-02
PT1372766E (en) 2010-05-25

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EEER Examination request
MKEX Expiry

Effective date: 20220328