CA2424029A1 - Coated medical devices - Google Patents

Coated medical devices Download PDF

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Publication number
CA2424029A1
CA2424029A1 CA002424029A CA2424029A CA2424029A1 CA 2424029 A1 CA2424029 A1 CA 2424029A1 CA 002424029 A CA002424029 A CA 002424029A CA 2424029 A CA2424029 A CA 2424029A CA 2424029 A1 CA2424029 A1 CA 2424029A1
Authority
CA
Canada
Prior art keywords
medical devices
medical device
organism
agents
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002424029A
Other languages
French (fr)
Other versions
CA2424029C (en
Inventor
David C. Lentz
Gerard H. Llanos
Mark B. Roller
Angelo Scopelianos
Kevin S. Weadock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cordis Corp
Original Assignee
Cordis Corporation
David C. Lentz
Gerard H. Llanos
Mark B. Roller
Angelo Scopelianos
Kevin S. Weadock
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27505363&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2424029(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US09/850,482 external-priority patent/US20010029351A1/en
Priority claimed from US09/887,464 external-priority patent/US7261735B2/en
Application filed by Cordis Corporation, David C. Lentz, Gerard H. Llanos, Mark B. Roller, Angelo Scopelianos, Kevin S. Weadock filed Critical Cordis Corporation
Publication of CA2424029A1 publication Critical patent/CA2424029A1/en
Application granted granted Critical
Publication of CA2424029C publication Critical patent/CA2424029C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/064—Surgical staples, i.e. penetrating the tissue
    • A61B17/0644—Surgical staples, i.e. penetrating the tissue penetrating the tissue, deformable to closed position
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
    • A61B17/115—Staplers for performing anastomosis in a single operation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/14—Post-treatment to improve physical properties
    • A61L17/145—Coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491—Surgical glue applicators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0469—Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06004—Means for attaching suture to needle
    • A61B2017/06028—Means for attaching suture to needle by means of a cylindrical longitudinal blind bore machined at the suture-receiving end of the needle, e.g. opposite to needle tip
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/064—Surgical staples, i.e. penetrating the tissue
    • A61B2017/0641—Surgical staples, i.e. penetrating the tissue having at least three legs as part of one single body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/064—Blood vessels with special features to facilitate anastomotic coupling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155—Adjacent bands being connected to each other
    • A61F2002/91558—Adjacent bands being connected to each other connected peak to peak
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0008—Fixation appliances for connecting prostheses to the body
    • A61F2220/0016—Fixation appliances for connecting prostheses to the body with sharp anchoring protrusions, e.g. barbs, pins, spikes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A61F2310/0097—Coating or prosthesis-covering structure made of pharmaceutical products, e.g. antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A61F2310/00976—Coating or prosthesis-covering structure made of proteins or of polypeptides, e.g. of bone morphogenic proteins BMP or of transforming growth factors TGF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
    • A61L2300/608—Coatings having two or more layers

Abstract

Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.
CA002424029A 2000-09-29 2001-09-28 Coated medical devices Expired - Lifetime CA2424029C (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US67588200A 2000-09-29 2000-09-29
US09/675,882 2000-09-29
US09/850,482 2001-05-07
US09/850,482 US20010029351A1 (en) 1998-04-16 2001-05-07 Drug combinations and delivery devices for the prevention and treatment of vascular disease
US09/887,464 US7261735B2 (en) 2001-05-07 2001-06-22 Local drug delivery devices and methods for maintaining the drug coatings thereon
US09/887,464 2001-06-22
US09/966,447 2001-09-28
US09/966,447 US8303609B2 (en) 2000-09-29 2001-09-28 Coated medical devices
PCT/US2001/030431 WO2002026139A1 (en) 2000-09-29 2001-09-28 Coated medical devices

Publications (2)

Publication Number Publication Date
CA2424029A1 true CA2424029A1 (en) 2002-04-04
CA2424029C CA2424029C (en) 2008-01-29

Family

ID=27505363

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002424029A Expired - Lifetime CA2424029C (en) 2000-09-29 2001-09-28 Coated medical devices

Country Status (10)

Country Link
US (1) US8303609B2 (en)
EP (1) EP1322235B2 (en)
JP (1) JP5100951B2 (en)
AT (1) ATE343969T1 (en)
AU (2) AU2001294869B2 (en)
CA (1) CA2424029C (en)
DE (1) DE60124285T3 (en)
ES (1) ES2275737T3 (en)
MX (1) MXPA03002871A (en)
WO (1) WO2002026139A1 (en)

Families Citing this family (202)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6006134A (en) 1998-04-30 1999-12-21 Medtronic, Inc. Method and device for electronically controlling the beating of a heart using venous electrical stimulation of nerve fibers
US6316522B1 (en) * 1997-08-18 2001-11-13 Scimed Life Systems, Inc. Bioresorbable hydrogel compositions for implantable prostheses
US20030129215A1 (en) * 1998-09-24 2003-07-10 T-Ram, Inc. Medical devices containing rapamycin analogs
US6890546B2 (en) 1998-09-24 2005-05-10 Abbott Laboratories Medical devices containing rapamycin analogs
ES2179646T3 (en) * 1998-04-27 2003-01-16 Surmodics Inc COATING THAT RELEASES A BIOACTIVE AGENT.
US20020188037A1 (en) * 1999-04-15 2002-12-12 Chudzik Stephen J. Method and system for providing bioactive agent release coating
US6790228B2 (en) 1999-12-23 2004-09-14 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
US7807211B2 (en) * 1999-09-03 2010-10-05 Advanced Cardiovascular Systems, Inc. Thermal treatment of an implantable medical device
US8016877B2 (en) 1999-11-17 2011-09-13 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8579966B2 (en) 1999-11-17 2013-11-12 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US7018406B2 (en) 1999-11-17 2006-03-28 Corevalve Sa Prosthetic valve for transluminal delivery
US8241274B2 (en) 2000-01-19 2012-08-14 Medtronic, Inc. Method for guiding a medical device
US7749245B2 (en) 2000-01-27 2010-07-06 Medtronic, Inc. Cardiac valve procedure methods and devices
US20030099683A1 (en) * 2000-03-18 2003-05-29 Michael Grunze Polyphosphazene derivatives
DE10191512D2 (en) * 2000-04-11 2003-03-13 Univ Heidelberg Envelopes and films made of poly-tri-fluoro-ethoxypolyphosphazen
US7419678B2 (en) 2000-05-12 2008-09-02 Cordis Corporation Coated medical devices for the prevention and treatment of vascular disease
AU2001273088A1 (en) 2000-06-30 2002-01-30 Viacor Incorporated Intravascular filter with debris entrapment mechanism
EP1179353A1 (en) * 2000-08-11 2002-02-13 B. Braun Melsungen Ag Antithrombogenic implants with coating of polyphosphazenes and a pharmacologically active agent
US20090004240A1 (en) * 2000-08-11 2009-01-01 Celonova Biosciences, Inc. Implants with a phosphazene-containing coating
US20060222756A1 (en) * 2000-09-29 2006-10-05 Cordis Corporation Medical devices, drug coatings and methods of maintaining the drug coatings thereon
US6746773B2 (en) 2000-09-29 2004-06-08 Ethicon, Inc. Coatings for medical devices
CN1225292C (en) * 2000-09-29 2005-11-02 伊西康公司 Coatings for medical devices
JP5100951B2 (en) 2000-09-29 2012-12-19 コーディス・コーポレイション Coated medical device
GB0100761D0 (en) 2001-01-11 2001-02-21 Biocompatibles Ltd Drug delivery from stents
US9080146B2 (en) 2001-01-11 2015-07-14 Celonova Biosciences, Inc. Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface
DE10100961B4 (en) * 2001-01-11 2005-08-04 Polyzenix Gmbh Body-compatible material and substrate coated with this material for the cultivation of cells and artificial organic implants constructed or grown from cells
US8038708B2 (en) 2001-02-05 2011-10-18 Cook Medical Technologies Llc Implantable device with remodelable material and covering material
US8182527B2 (en) 2001-05-07 2012-05-22 Cordis Corporation Heparin barrier coating for controlled drug release
US6656506B1 (en) * 2001-05-09 2003-12-02 Advanced Cardiovascular Systems, Inc. Microparticle coated medical device
US7247313B2 (en) * 2001-06-27 2007-07-24 Advanced Cardiovascular Systems, Inc. Polyacrylates coatings for implantable medical devices
US8623077B2 (en) 2001-06-29 2014-01-07 Medtronic, Inc. Apparatus for replacing a cardiac valve
US8771302B2 (en) 2001-06-29 2014-07-08 Medtronic, Inc. Method and apparatus for resecting and replacing an aortic valve
US7544206B2 (en) 2001-06-29 2009-06-09 Medtronic, Inc. Method and apparatus for resecting and replacing an aortic valve
FR2826863B1 (en) 2001-07-04 2003-09-26 Jacques Seguin ASSEMBLY FOR PLACING A PROSTHETIC VALVE IN A BODY CONDUIT
DE10135315A1 (en) * 2001-07-19 2003-01-30 Bayer Ag stents
FR2828091B1 (en) 2001-07-31 2003-11-21 Seguin Jacques ASSEMBLY ALLOWING THE PLACEMENT OF A PROTHETIC VALVE IN A BODY DUCT
EP1432380B1 (en) * 2001-08-17 2006-09-27 Polyzenix GmbH Device based on nitinol with a polyphosphazene coating
US7097659B2 (en) 2001-09-07 2006-08-29 Medtronic, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US7169785B2 (en) 2001-09-21 2007-01-30 Reddy Us Therapeutics, Inc. Methods and compositions of novel triazine compounds
US7108701B2 (en) * 2001-09-28 2006-09-19 Ethicon, Inc. Drug releasing anastomosis devices and methods for treating anastomotic sites
US20030065345A1 (en) * 2001-09-28 2003-04-03 Kevin Weadock Anastomosis devices and methods for treating anastomotic sites
US20030065377A1 (en) 2001-09-28 2003-04-03 Davila Luis A. Coated medical devices
US20060009840A1 (en) * 2002-03-15 2006-01-12 Hossainy Syed F Carrier for releasing a therapeutic substance in response to the presence of an enzyme
US8241308B2 (en) 2002-04-24 2012-08-14 Boston Scientific Scimed, Inc. Tissue fastening devices and processes that promote tissue adhesion
US20030204168A1 (en) * 2002-04-30 2003-10-30 Gjalt Bosma Coated vascular devices
MXPA04011144A (en) * 2002-05-10 2005-08-16 Johnson & Johnson Method of making a medical device having a thin wall tubular membrane over a structural frame.
US7270675B2 (en) * 2002-05-10 2007-09-18 Cordis Corporation Method of forming a tubular membrane on a structural frame
US7351256B2 (en) 2002-05-10 2008-04-01 Cordis Corporation Frame based unidirectional flow prosthetic implant
US7485141B2 (en) 2002-05-10 2009-02-03 Cordis Corporation Method of placing a tubular membrane on a structural frame
US20030229392A1 (en) * 2002-06-03 2003-12-11 Wong Samuel J. Drug eluted vascular graft
US7097850B2 (en) 2002-06-18 2006-08-29 Surmodics, Inc. Bioactive agent release coating and controlled humidity method
US7217426B1 (en) 2002-06-21 2007-05-15 Advanced Cardiovascular Systems, Inc. Coatings containing polycationic peptides for cardiovascular therapy
WO2004002367A1 (en) * 2002-06-27 2004-01-08 Microport Medical (Shanghai) Co., Ltd. Drug eluting stent
US20080138377A1 (en) * 2002-07-05 2008-06-12 Celonova Biosciences, Inc. Vasodilator Eluting Luminal Stent Devices With A Specific Polyphosphazene Coating and Methods for Their Manufacture and Use
US20080138433A1 (en) * 2002-07-05 2008-06-12 Celonova Biosciences, Inc. Vasodilator eluting blood storage and administration devices with a specific polyphosphazene coating and methods for their manufacture and use
CA2494188A1 (en) * 2002-08-13 2004-02-19 Medtronic, Inc. Active agent delivery system including a hydrophobic cellulose derivative
WO2004014448A1 (en) * 2002-08-13 2004-02-19 Medtronic, Inc. Active agent delivery system including a hydrophilic polymer, medical device, and method
US20040047911A1 (en) * 2002-08-13 2004-03-11 Medtronic, Inc. Active agent delivery system including a poly(ethylene-co-(meth)Acrylate), medical device, and method
JP2006500088A (en) * 2002-08-13 2006-01-05 メドトロニック・インコーポレーテッド Medical device showing improved adhesion between polymer coating and support
CA2495172A1 (en) * 2002-08-13 2004-02-19 Medtronic, Inc. Active agent delivery systems, medical devices, and methods
US7438925B2 (en) * 2002-08-26 2008-10-21 Biovention Holdings Ltd. Drug eluting coatings for medical implants
US20040044404A1 (en) * 2002-08-30 2004-03-04 Stucke Sean M. Retention coatings for delivery systems
AU2003275190A1 (en) * 2002-09-18 2004-04-08 Medtronic Vascular, Inc. Controllable drug releasing gradient coatings for medical devices
EP1569762B1 (en) * 2002-10-22 2007-10-03 Medtronic Vascular, Inc. Stent with intermittent coating
US20060121080A1 (en) * 2002-11-13 2006-06-08 Lye Whye K Medical devices having nanoporous layers and methods for making the same
US7491234B2 (en) * 2002-12-03 2009-02-17 Boston Scientific Scimed, Inc. Medical devices for delivery of therapeutic agents
US7758880B2 (en) * 2002-12-11 2010-07-20 Advanced Cardiovascular Systems, Inc. Biocompatible polyacrylate compositions for medical applications
US7776926B1 (en) 2002-12-11 2010-08-17 Advanced Cardiovascular Systems, Inc. Biocompatible coating for implantable medical devices
US7758881B2 (en) * 2004-06-30 2010-07-20 Advanced Cardiovascular Systems, Inc. Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
JP2006517850A (en) * 2003-02-18 2006-08-03 メドトロニック・インコーポレーテッド Occlusion resistant hydrocephalus shunt
US20040167572A1 (en) * 2003-02-20 2004-08-26 Roth Noah M. Coated medical devices
US20050131524A1 (en) * 2003-02-25 2005-06-16 Majercak David C. Method for treating a bifurcated vessel
US7942920B2 (en) * 2003-02-25 2011-05-17 Cordis Corporation Stent with nested fingers for enhanced vessel coverage
US7918884B2 (en) * 2003-02-25 2011-04-05 Cordis Corporation Stent for treatment of bifurcated lesions
US20090093875A1 (en) 2007-05-01 2009-04-09 Abbott Laboratories Drug eluting stents with prolonged local elution profiles with high local concentrations and low systemic concentrations
EP2918296A1 (en) * 2003-02-28 2015-09-16 Biointeractions Ltd. Polymeric network system for medical devices and methods of use
WO2004084769A2 (en) * 2003-03-28 2004-10-07 Damian John Conway Stents
US8791171B2 (en) 2003-05-01 2014-07-29 Abbott Cardiovascular Systems Inc. Biodegradable coatings for implantable medical devices
US8246974B2 (en) 2003-05-02 2012-08-21 Surmodics, Inc. Medical devices and methods for producing the same
AU2004237774B2 (en) 2003-05-02 2009-09-10 Surmodics, Inc. Implantable controlled release bioactive agent delivery device
US7279174B2 (en) * 2003-05-08 2007-10-09 Advanced Cardiovascular Systems, Inc. Stent coatings comprising hydrophilic additives
EP1653865A2 (en) * 2003-05-23 2006-05-10 Angiotech International Ag Anastomotic connector devices
US20040236414A1 (en) * 2003-05-23 2004-11-25 Brar Balbir S. Devices and methods for treatment of stenotic regions
US20060217797A1 (en) * 2003-05-23 2006-09-28 Wong Samuel J Asymmetric drug eluting hemodialysis graft
US20050118344A1 (en) 2003-12-01 2005-06-02 Pacetti Stephen D. Temperature controlled crimping
US20050037052A1 (en) * 2003-08-13 2005-02-17 Medtronic Vascular, Inc. Stent coating with gradient porosity
WO2005018702A2 (en) * 2003-08-13 2005-03-03 Medtronic, Inc. Active agent delivery systems including a miscible polymer blend, medical devices, and methods
EP1660145A2 (en) * 2003-08-13 2006-05-31 Medtronic, Inc. Active agent delivery systems, including a single layer of a miscible polymer blend, medical devices and methods
WO2005030091A2 (en) * 2003-09-25 2005-04-07 Scios Inc. Stents and intra-luminal prostheses containing map kinase inhibitors
US9579194B2 (en) 2003-10-06 2017-02-28 Medtronic ATS Medical, Inc. Anchoring structure with concave landing zone
WO2005040163A1 (en) 2003-10-28 2005-05-06 Dr. Reddy's Laboratories Ltd Heterocyclic compounds that block the effects of advanced glycation end products (age)
US7347869B2 (en) 2003-10-31 2008-03-25 Cordis Corporation Implantable valvular prosthesis
US7070616B2 (en) * 2003-10-31 2006-07-04 Cordis Corporation Implantable valvular prosthesis
EP1682196A2 (en) * 2003-11-10 2006-07-26 Angiotech International Ag Medical implants and anti-scarring agents
EP1687043A2 (en) * 2003-11-20 2006-08-09 Angiotech International Ag Electrical devices and anti-scarring agents
US8747881B2 (en) * 2003-12-19 2014-06-10 Cordis Corporation Intraluminal medical devices in combination with therapeutic agents
US8652502B2 (en) * 2003-12-19 2014-02-18 Cordis Corporation Local vascular delivery of trichostatin A alone or in combination with sirolimus to prevent restenosis following vascular injury
ITTO20040135A1 (en) 2004-03-03 2004-06-03 Sorin Biomedica Cardio Spa CARDIAC VALVE PROSTHESIS
US8828416B2 (en) * 2004-03-09 2014-09-09 Cordis Corporation Local vascular delivery of topotecan in combination with rapamycin to prevent restenosis following vascular injury
US8778014B1 (en) 2004-03-31 2014-07-15 Advanced Cardiovascular Systems, Inc. Coatings for preventing balloon damage to polymer coated stents
US20050232965A1 (en) * 2004-04-15 2005-10-20 Robert Falotico Local administration of a combination of rapamycin and 17 beta-estradiol for the treatment of vulnerable plaque
EP1753374A4 (en) 2004-04-23 2010-02-10 3F Therapeutics Inc Implantable prosthetic valve
US9561309B2 (en) * 2004-05-27 2017-02-07 Advanced Cardiovascular Systems, Inc. Antifouling heparin coatings
US8512388B1 (en) * 2004-06-24 2013-08-20 Advanced Cardiovascular Systems, Inc. Stent delivery catheter with improved stent retention and method of making same
US8709469B2 (en) 2004-06-30 2014-04-29 Abbott Cardiovascular Systems Inc. Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
US20070208413A1 (en) * 2004-07-30 2007-09-06 Kaneka Corporation Stent
US20060029640A1 (en) * 2004-08-05 2006-02-09 Gilbert Jeremy L Medical devices with surface modification for regulating cell growth on or near the surface
US7244443B2 (en) 2004-08-31 2007-07-17 Advanced Cardiovascular Systems, Inc. Polymers of fluorinated monomers and hydrophilic monomers
EP1802237B1 (en) * 2004-10-18 2018-08-08 Covidien LP Compression anastomosis device
US9114162B2 (en) 2004-10-25 2015-08-25 Celonova Biosciences, Inc. Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same
US9107850B2 (en) 2004-10-25 2015-08-18 Celonova Biosciences, Inc. Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same
US20210299056A9 (en) 2004-10-25 2021-09-30 Varian Medical Systems, Inc. Color-Coded Polymeric Particles of Predetermined Size for Therapeutic and/or Diagnostic Applications and Related Methods
US20060088566A1 (en) 2004-10-27 2006-04-27 Scimed Life Systems, Inc.,A Corporation Method of controlling drug release from a coated medical device through the use of nucleating agents
US20060093647A1 (en) * 2004-10-29 2006-05-04 Villafana Manuel A Multiple layer coating composition
DE102005003632A1 (en) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Catheter for the transvascular implantation of heart valve prostheses
ITTO20050074A1 (en) 2005-02-10 2006-08-11 Sorin Biomedica Cardio Srl CARDIAC VALVE PROSTHESIS
ES2558534T3 (en) * 2005-02-18 2016-02-05 The Cleveland Clinic Foundation Device to replace a heart valve
WO2006113906A1 (en) * 2005-04-20 2006-10-26 The Cleveland Clinic Foundation Apparatus and method for replacing a cardiac valve
US7914569B2 (en) 2005-05-13 2011-03-29 Medtronics Corevalve Llc Heart valve prosthesis and methods of manufacture and use
TWI289765B (en) 2005-07-20 2007-11-11 Quanta Comp Inc Devices a methods for signal switching and processing
US20070078510A1 (en) 2005-09-26 2007-04-05 Ryan Timothy R Prosthetic cardiac and venous valves
US20090053391A1 (en) * 2005-12-06 2009-02-26 Ludwig Florian N Method Of Coating A Drug-Releasing Layer Onto A Substrate
US10029034B2 (en) * 2005-12-15 2018-07-24 CARDINAL HEALTH SWITZERLAND 515 GmbH Drug-eluting articles with improved drug release profiles
US8075615B2 (en) 2006-03-28 2011-12-13 Medtronic, Inc. Prosthetic cardiac valve formed from pericardium material and methods of making same
US20070254003A1 (en) * 2006-05-01 2007-11-01 Pu Zhou Non-sticky coatings with therapeutic agents for medical devices
US20080095918A1 (en) * 2006-06-14 2008-04-24 Kleiner Lothar W Coating construct with enhanced interfacial compatibility
US8388573B1 (en) 2006-06-28 2013-03-05 Abbott Cardiovascular Systems Inc. Local delivery with a balloon covered by a cage
US9028859B2 (en) 2006-07-07 2015-05-12 Advanced Cardiovascular Systems, Inc. Phase-separated block copolymer coatings for implantable medical devices
US10219884B2 (en) 2006-07-10 2019-03-05 First Quality Hygienic, Inc. Resilient device
CN104257450B (en) 2006-07-10 2017-05-10 第一次质量卫生公司 Resilient Device
US8047980B2 (en) 2006-07-10 2011-11-01 Mcneil-Ppc, Inc. Method of treating urinary incontinence
US8613698B2 (en) 2006-07-10 2013-12-24 Mcneil-Ppc, Inc. Resilient device
US10004584B2 (en) 2006-07-10 2018-06-26 First Quality Hygienic, Inc. Resilient intravaginal device
US20080065044A1 (en) * 2006-09-08 2008-03-13 Abbott Cardiovascular Systems Inc. Bioactive agent-containing implantable rings
US20080065196A1 (en) * 2006-09-12 2008-03-13 Michael Wayne Davis Intra-Columnar Cell Features to Improve Drug Distribution and Scaffolding of a Stent
US11304800B2 (en) 2006-09-19 2022-04-19 Medtronic Ventor Technologies Ltd. Sinus-engaging valve fixation member
US8348996B2 (en) 2006-09-19 2013-01-08 Medtronic Ventor Technologies Ltd. Valve prosthesis implantation techniques
US8834564B2 (en) 2006-09-19 2014-09-16 Medtronic, Inc. Sinus-engaging valve fixation member
US20080095816A1 (en) * 2006-10-10 2008-04-24 Celonova Biosciences, Inc. Compositions and Devices Comprising Silicone and Specific Polyphosphazenes
KR101083471B1 (en) * 2006-10-10 2011-11-16 셀로노바 바이오사이언시즈, 인코포레이티드 Bioprosthetic Heart Valve with Polyphosphazene
WO2008047354A2 (en) 2006-10-16 2008-04-24 Ventor Technologies Ltd. Transapical delivery system with ventriculo-arterial overflow bypass
US7713541B1 (en) 2006-11-21 2010-05-11 Abbott Cardiovascular Systems Inc. Zwitterionic terpolymers, method of making and use on medical devices
WO2008064058A2 (en) * 2006-11-21 2008-05-29 Abbott Laboratories Use of a terpolymer of tetrafluoroethylene, hexafluoropropylene, and vinylidene fluoride in drug eluting coatings
US20080118541A1 (en) * 2006-11-21 2008-05-22 Abbott Laboratories Use of a terpolymer of tetrafluoroethylene, hexafluoropropylene, and vinylidene fluoride in drug eluting coatings on medical devices
US8747459B2 (en) 2006-12-06 2014-06-10 Medtronic Corevalve Llc System and method for transapical delivery of an annulus anchored self-expanding valve
CA2673528A1 (en) 2006-12-20 2008-07-24 Boston Scientific Limited Stent with a coating for delivering a therapeutic agent
WO2008089365A2 (en) * 2007-01-19 2008-07-24 The Cleveland Clinic Foundation Method for implanting a cardiovascular valve
EP2129333B1 (en) 2007-02-16 2019-04-03 Medtronic, Inc Replacement prosthetic heart valves
US7896915B2 (en) 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
FR2915087B1 (en) 2007-04-20 2021-11-26 Corevalve Inc IMPLANT FOR TREATMENT OF A HEART VALVE, IN PARTICULAR OF A MITRAL VALVE, EQUIPMENT INCLUDING THIS IMPLANT AND MATERIAL FOR PLACING THIS IMPLANT.
US20080286332A1 (en) 2007-05-14 2008-11-20 Pacetti Stephen D Implantable medical devices with a topcoat layer of phosphoryl choline acrylate polymer for reduced thrombosis, and improved mechanical properties
US8802184B2 (en) 2007-05-30 2014-08-12 Abbott Cardiovascular Systems Inc. Medical devices containing biobeneficial particles
US8293260B2 (en) 2007-06-05 2012-10-23 Abbott Cardiovascular Systems Inc. Elastomeric copolymer coatings containing poly (tetramethyl carbonate) for implantable medical devices
US8747458B2 (en) 2007-08-20 2014-06-10 Medtronic Ventor Technologies Ltd. Stent loading tool and method for use thereof
US8100855B2 (en) 2007-09-17 2012-01-24 Abbott Cardiovascular Systems, Inc. Methods and devices for eluting agents to a vessel
US10856970B2 (en) 2007-10-10 2020-12-08 Medtronic Ventor Technologies Ltd. Prosthetic heart valve for transfemoral delivery
US9848981B2 (en) 2007-10-12 2017-12-26 Mayo Foundation For Medical Education And Research Expandable valve prosthesis with sealing mechanism
US8142490B2 (en) 2007-10-24 2012-03-27 Cordis Corporation Stent segments axially connected by thin film
EP2254512B1 (en) 2008-01-24 2016-01-06 Medtronic, Inc. Markers for prosthetic heart valves
US8157853B2 (en) 2008-01-24 2012-04-17 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
JP5687070B2 (en) 2008-01-24 2015-03-18 メドトロニック，インコーポレイテッド Stent for prosthetic heart valve
US9393115B2 (en) 2008-01-24 2016-07-19 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US9149358B2 (en) 2008-01-24 2015-10-06 Medtronic, Inc. Delivery systems for prosthetic heart valves
EP2254513B1 (en) 2008-01-24 2015-10-28 Medtronic, Inc. Stents for prosthetic heart valves
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
BR112012021347A2 (en) 2008-02-26 2019-09-24 Jenavalve Tecnology Inc stent for positioning and anchoring a valve prosthesis at an implantation site in a patient's heart
EP3005984A1 (en) 2008-02-28 2016-04-13 Medtronic Inc. Prosthetic heart valve systems
US8313525B2 (en) 2008-03-18 2012-11-20 Medtronic Ventor Technologies, Ltd. Valve suturing and implantation procedures
US8430927B2 (en) 2008-04-08 2013-04-30 Medtronic, Inc. Multiple orifice implantable heart valve and methods of implantation
US8696743B2 (en) 2008-04-23 2014-04-15 Medtronic, Inc. Tissue attachment devices and methods for prosthetic heart valves
US8312825B2 (en) 2008-04-23 2012-11-20 Medtronic, Inc. Methods and apparatuses for assembly of a pericardial prosthetic heart valve
ATE554731T1 (en) 2008-05-16 2012-05-15 Sorin Biomedica Cardio Srl ATRAAUMATIC PROSTHETIC HEART VALVE PROSTHESIS
EP4018967A1 (en) 2008-09-15 2022-06-29 Medtronic Ventor Technologies Ltd Prosthetic heart valve having identifiers for aiding in radiographic positioning
US8721714B2 (en) 2008-09-17 2014-05-13 Medtronic Corevalve Llc Delivery system for deployment of medical devices
US8092822B2 (en) 2008-09-29 2012-01-10 Abbott Cardiovascular Systems Inc. Coatings including dexamethasone derivatives and analogs and olimus drugs
US8137398B2 (en) 2008-10-13 2012-03-20 Medtronic Ventor Technologies Ltd Prosthetic valve having tapered tip when compressed for delivery
US8986361B2 (en) 2008-10-17 2015-03-24 Medtronic Corevalve, Inc. Delivery system for deployment of medical devices
US8834563B2 (en) 2008-12-23 2014-09-16 Sorin Group Italia S.R.L. Expandable prosthetic valve having anchoring appendages
ES2523218T3 (en) 2009-04-27 2014-11-24 Sorin Group Italia S.R.L. Prosthetic vascular duct
US8808369B2 (en) 2009-10-05 2014-08-19 Mayo Foundation For Medical Education And Research Minimally invasive aortic valve replacement
US9226826B2 (en) 2010-02-24 2016-01-05 Medtronic, Inc. Transcatheter valve structure and methods for valve delivery
US8652204B2 (en) 2010-04-01 2014-02-18 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
IT1400327B1 (en) 2010-05-21 2013-05-24 Sorin Biomedica Cardio Srl SUPPORT DEVICE FOR VALVULAR PROSTHESIS AND CORRESPONDING CORRESPONDENT.
CN103002833B (en) 2010-05-25 2016-05-11 耶拿阀门科技公司 Artificial heart valve and comprise artificial heart valve and support through conduit carry interior prosthese
CN103118629A (en) 2010-09-01 2013-05-22 美敦力瓦斯科尔勒戈尔韦有限公司 Prosthetic valve support structure
EP2486894B1 (en) 2011-02-14 2021-06-09 Sorin Group Italia S.r.l. Sutureless anchoring device for cardiac valve prostheses
EP2486893B1 (en) 2011-02-14 2017-07-05 Sorin Group Italia S.r.l. Sutureless anchoring device for cardiac valve prostheses
EP2609893B1 (en) 2011-12-29 2014-09-03 Sorin Group Italia S.r.l. A kit for implanting prosthetic vascular conduits
JP6549482B2 (en) 2012-06-01 2019-07-24 サーモディクス，インコーポレイテッド Device and method for coating a balloon catheter
US9827401B2 (en) 2012-06-01 2017-11-28 Surmodics, Inc. Apparatus and methods for coating medical devices
WO2014171184A1 (en) 2013-04-16 2014-10-23 株式会社カネカ Medical tubular body
JP6561044B2 (en) 2013-05-03 2019-08-14 メドトロニック，インコーポレイテッド Valve transfer tool
JP6563394B2 (en) 2013-08-30 2019-08-21 イェーナヴァルヴ テクノロジー インコーポレイテッド Radially foldable frame for an artificial valve and method for manufacturing the frame
WO2016148648A1 (en) * 2015-03-19 2016-09-22 Nanyang Technological University A stent assembly and method of preparing the stent assembly
JP6767388B2 (en) 2015-05-01 2020-10-14 イェーナヴァルヴ テクノロジー インコーポレイテッド Devices and methods to reduce the proportion of pacemakers in heart valve replacement
WO2017048989A1 (en) 2015-09-15 2017-03-23 Fong Kenton D Devices and methods for anchoring a sheath in a tissue cavity
EP4183371A1 (en) 2016-05-13 2023-05-24 JenaValve Technology, Inc. Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system
WO2018138658A1 (en) 2017-01-27 2018-08-02 Jenavalve Technology, Inc. Heart valve mimicry
US10716558B2 (en) 2017-08-04 2020-07-21 Ethicon, Inc. Tissue anchors having bi-directional arrays of barbed pins for joining tissue layers
WO2019224577A1 (en) 2018-05-23 2019-11-28 Sorin Group Italia S.R.L. A cardiac valve prosthesis
WO2020112816A1 (en) 2018-11-29 2020-06-04 Surmodics, Inc. Apparatus and methods for coating medical devices
US11819590B2 (en) 2019-05-13 2023-11-21 Surmodics, Inc. Apparatus and methods for coating medical devices

Family Cites Families (611)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US861659A (en) 1906-10-03 1907-07-30 Edgar F Johnston Flexible shafting.
US2357881A (en) 1941-05-13 1944-09-12 Nat Oil Prod Co Process of treating glyceride oils
US2425753A (en) 1941-12-09 1947-08-19 Byron Jackson Co Elevator device
US2424029A (en) 1942-10-10 1947-07-15 Herbert L J Haller Cyclopropylalkyl ethers as insecticides
DE1078329B (en) 1955-04-27 1960-03-24 Du Pont Process for the production of an elastic copolymer from vinylidene fluoride and another fluoroolefin
US3178399A (en) 1961-08-10 1965-04-13 Minnesota Mining & Mfg Fluorine-containing polymers and preparation thereof
US3279996A (en) 1962-08-28 1966-10-18 Jr David M Long Polysiloxane carrier for controlled release of drugs and other agents
US3585707A (en) 1966-04-13 1971-06-22 Cordis Corp Method of making tubular products
GB1205743A (en) 1966-07-15 1970-09-16 Nat Res Dev Surgical dilator
US3526005A (en) 1967-06-29 1970-09-01 Gulf General Atomic Inc Method of preparing an intravascular defect by implanting a pyrolytic carbon coated prosthesis
US3608095A (en) 1970-03-05 1971-09-28 Federal Tool Eng Co Method of fixing hair pieces to scalps
US3599641A (en) 1970-03-13 1971-08-17 David S Sheridan Combination connector and channel closure system for catheters
US3657744A (en) 1970-05-08 1972-04-25 Univ Minnesota Method for fixing prosthetic implants in a living body
US3675647A (en) 1970-08-05 1972-07-11 Alza Corp Intrauterine contraceptive device
US4069307A (en) 1970-10-01 1978-01-17 Alza Corporation Drug-delivery device comprising certain polymeric materials for controlled release of drug
US3726279A (en) 1970-10-08 1973-04-10 Carolina Medical Electronics I Hemostatic vascular cuff
GB1269917A (en) 1971-01-12 1972-04-06 Bromsregulator Svenska Ab Improvements in pneumatic cylinder-piston units for railway vehicle brake riggings
US3774615A (en) 1971-02-08 1973-11-27 Ceskoslovenska Akademie Ved Device for connecting or joining the ends of interrupted tubular organs in surgical operations without stitching
US3779805A (en) 1971-05-19 1973-12-18 Bell Telephone Labor Inc Method of making waveguide mode filter
US3948254A (en) 1971-11-08 1976-04-06 Alza Corporation Novel drug delivery device
US3765414A (en) 1972-03-10 1973-10-16 Hydro Med Sciences Inc Drug release system
ZA737247B (en) 1972-09-29 1975-04-30 Ayerst Mckenna & Harrison Rapamycin and process of preparation
US4118532A (en) 1972-10-24 1978-10-03 Homsy Charles A Implantable material and method of preparing same
US3921636A (en) * 1973-01-15 1975-11-25 Alza Corp Novel drug delivery device
US3959078A (en) 1973-05-18 1976-05-25 Midwest Research Institute Enzyme immobilization with a thermochemical-photochemical bifunctional agent
US3974526A (en) 1973-07-06 1976-08-17 Dardik Irving I Vascular prostheses and process for producing the same
US3932627A (en) 1974-02-04 1976-01-13 Rescue Products, Inc. Siver-heparin-allantoin complex
US3952747A (en) 1974-03-28 1976-04-27 Kimmell Jr Garman O Filter and filter insertion instrument
US3923939A (en) * 1974-06-07 1975-12-02 Alza Corp Process for improving release kinetics of a monolithic drug delivery device
US3968800A (en) 1974-09-17 1976-07-13 Vilasi Joseph A Device for insertion into a body opening
US3952334A (en) 1974-11-29 1976-04-27 General Atomic Company Biocompatible carbon prosthetic devices
US4076285A (en) 1975-08-01 1978-02-28 Erika, Inc. Laminar flow connector for conduits
US4323071A (en) 1978-04-24 1982-04-06 Advanced Catheter Systems, Inc. Vascular guiding catheter assembly and vascular dilating catheter assembly and a combination thereof and methods of making the same
JPS6037733B2 (en) 1978-10-12 1985-08-28 住友電気工業株式会社 Tubular organ prosthesis material and its manufacturing method
JPS6037735B2 (en) 1978-10-18 1985-08-28 住友電気工業株式会社 Artificial blood vessel
US4292965A (en) 1978-12-29 1981-10-06 The Population Council, Inc. Intravaginal ring
US4214587A (en) * 1979-02-12 1980-07-29 Sakura Chester Y Jr Anastomosis device and method
US4299226A (en) 1979-08-08 1981-11-10 Banka Vidya S Coronary dilation method
US4300244A (en) 1979-09-19 1981-11-17 Carbomedics, Inc. Cardiovascular grafts
US4252858A (en) 1979-10-15 1981-02-24 Raychem Corporation Coated article and hot melt adhesive comprising fluorocarbon elastomer ethylene copolymer and tackifier
US4312920A (en) 1979-11-07 1982-01-26 The United States Of America As Represented By The Department Of Health & Human Services Polymer alloy blood compatible surface
SU1088712A1 (en) 1979-11-14 1984-04-30 Всесоюзный научно-исследовательский и испытательный институт медицинской техники Apparatus for circular suture of blood vessels
US4390599A (en) 1980-07-31 1983-06-28 Raychem Corporation Enhanced recovery memory metal device
US4423183A (en) 1980-09-16 1983-12-27 David Hudson, Inc. Fluoroelastomer film compositions and solutions containing fatty polyamide curatives
US4388735A (en) 1980-11-03 1983-06-21 Shiley Inc. Low profile prosthetic xenograft heart valve
US4455690A (en) 1980-11-06 1984-06-26 Homsy Charles A Structure for in vivo implanation
US4368736A (en) 1980-11-17 1983-01-18 Kaster Robert L Anastomotic fitting
US4366819A (en) 1980-11-17 1983-01-04 Kaster Robert L Anastomotic fitting
JPS57144756A (en) 1981-03-04 1982-09-07 Koken Kk Impermeable laminated film
US4678466A (en) 1981-06-25 1987-07-07 Rosenwald Peter L Internal medication delivery method and vehicle
AU8954282A (en) 1981-09-16 1983-04-08 Wallsten, H.I. Device for application in blood vessels or other difficultly accessible locations and its use
SE8200751L (en) 1982-02-09 1983-08-10 Olle Larm PROCEDURE FOR COVALENT COUPLING FOR MANUFACTURE OF CONJUGATE AND REQUIRED PRODUCTS
SE456347B (en) 1982-02-09 1988-09-26 Ird Biomaterial Ab SURFACE MODIFIED SOLID SUBSTRATE AND PROCEDURES FOR PRODUCING THEREOF
EP0086627B1 (en) 1982-02-12 1985-08-28 Unitika Ltd. Anti-cancer device
DE3205942A1 (en) 1982-02-19 1983-09-08 Ljubomir Dr. Skopje Vasilev Balloon-tipped catheter with a mobile tip which permits complete voiding of the bladder
SE445884B (en) 1982-04-30 1986-07-28 Medinvent Sa DEVICE FOR IMPLANTATION OF A RODFORM PROTECTION
SE431609B (en) 1982-06-24 1984-02-20 Unilink Ab SURGICAL INSTRUMENT FOR THE ASTAD COMMAND OF ANASTOMOS AND ITS PARTS
US4917091A (en) 1982-06-24 1990-04-17 Unilink Ab Annular fastening means
US5702699A (en) 1982-09-23 1997-12-30 Cetus Corporation Process for the recovery of lipophilic proteins
US4722906A (en) 1982-09-29 1988-02-02 Bio-Metric Systems, Inc. Binding reagents and methods
US4512338A (en) 1983-01-25 1985-04-23 Balko Alexander B Process for restoring patency to body vessels
US4503569A (en) 1983-03-03 1985-03-12 Dotter Charles T Transluminally placed expandable graft prosthesis
US5034265A (en) 1983-08-01 1991-07-23 Washington Research Foundation Plasma gas discharge treatment for improving the compatibility of biomaterials
US4656083A (en) 1983-08-01 1987-04-07 Washington Research Foundation Plasma gas discharge treatment for improving the biocompatibility of biomaterials
US4550447A (en) 1983-08-03 1985-11-05 Shiley Incorporated Vascular graft prosthesis
CA1232814A (en) 1983-09-16 1988-02-16 Hidetoshi Sakamoto Guide wire for catheter
US4560374A (en) 1983-10-17 1985-12-24 Hammerslag Julius G Method for repairing stenotic vessels
US5275622A (en) 1983-12-09 1994-01-04 Harrison Medical Technologies, Inc. Endovascular grafting apparatus, system and method and devices for use therewith
US4787899A (en) 1983-12-09 1988-11-29 Lazarus Harrison M Intraluminal graft device, system and method
US4676241A (en) 1984-01-16 1987-06-30 W.L.G. Technology Ventilation tube swivel
US5197977A (en) 1984-01-30 1993-03-30 Meadox Medicals, Inc. Drug delivery collagen-impregnated synthetic vascular graft
US4727873A (en) 1984-04-17 1988-03-01 Mobin Uddin Kazi Embolus trap
US4562596A (en) 1984-04-25 1986-01-07 Elliot Kornberg Aortic graft, device and method for performing an intraluminal abdominal aortic aneurysm repair
US4687482A (en) 1984-04-27 1987-08-18 Scripps Clinic And Research Foundation Vascular prosthesis
US4753652A (en) 1984-05-04 1988-06-28 Children's Medical Center Corporation Biomaterial implants which resist calcification
DK151404C (en) 1984-05-23 1988-07-18 Cook Europ Aps William FULLY FILTER FOR IMPLANTATION IN A PATIENT'S BLOOD
US4564013A (en) 1984-05-24 1986-01-14 Ethicon, Inc. Surgical filaments from vinylidene fluoride copolymers
US4580568A (en) 1984-10-01 1986-04-08 Cook, Incorporated Percutaneous endovascular stent and method for insertion thereof
FR2573646B1 (en) 1984-11-29 1988-11-25 Celsa Composants Electr Sa PERFECTED FILTER, PARTICULARLY FOR THE RETENTION OF BLOOD CLOTS
US4689046A (en) 1985-03-11 1987-08-25 Carbomedics, Inc. Heart valve prosthesis
CN85100493A (en) 1985-04-01 1986-08-13 中国科学院上海有机化学研究所 Tetrafluoroethylene and vinylidene fluoride copolymers room temperature coating
CN85100445A (en) 1985-04-01 1986-07-09 中国科学院上海有机化学研究所 The film of tetrafluoroethylene and vinylidene fluoride copolymers, preparation method and application
SE450809B (en) 1985-04-10 1987-08-03 Medinvent Sa PLANT TOPIC PROVIDED FOR MANUFACTURING A SPIRAL SPRING SUITABLE FOR TRANSLUMINAL IMPLANTATION AND MANUFACTURED SPIRAL SPRINGS
WO1986007541A1 (en) 1985-06-19 1986-12-31 Yasushi Zyo Composition which can impart antithrombotic ability and medical apparatus to be in contact with blood
CH667209A5 (en) 1985-07-02 1988-09-30 Sulzer Ag MEDICAL DEPOT PROBE.
US4733665C2 (en) 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
US5102417A (en) 1985-11-07 1992-04-07 Expandable Grafts Partnership Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
US4871357A (en) 1986-01-21 1989-10-03 Baxter International Inc. Ionic heparin coating
EP0257091B1 (en) 1986-02-24 1993-07-28 Robert E. Fischell An intravascular stent and percutaneous insertion system
US4749585A (en) 1986-04-11 1988-06-07 University Of Medicine And Dentistry Of New Jersey Antibiotic bonded prosthesis and process for producing same
SE453258B (en) 1986-04-21 1988-01-25 Medinvent Sa ELASTIC, SELF-EXPANDING PROTEST AND PROCEDURE FOR ITS MANUFACTURING
US4665905A (en) 1986-06-09 1987-05-19 Brown Charles S Dynamic elbow and knee extension brace
US4786500A (en) 1986-06-26 1988-11-22 Alza Corporation Programmable agent delivery system
US4740207A (en) 1986-09-10 1988-04-26 Kreamer Jeffry W Intralumenal graft
US4800882A (en) 1987-03-13 1989-01-31 Cook Incorporated Endovascular stent and delivery system
US5041126A (en) 1987-03-13 1991-08-20 Cook Incorporated Endovascular stent and delivery system
US4907336A (en) 1987-03-13 1990-03-13 Cook Incorporated Method of making an endovascular stent and delivery system
US4876109A (en) 1987-04-13 1989-10-24 Cardiac Pacemakers, Inc. Soluble covering for cardiac pacing electrode
US4816339A (en) 1987-04-28 1989-03-28 Baxter International Inc. Multi-layered poly(tetrafluoroethylene)/elastomer materials useful for in vivo implantation
US5061276A (en) 1987-04-28 1991-10-29 Baxter International Inc. Multi-layered poly(tetrafluoroethylene)/elastomer materials useful for in vivo implantation
NL8701337A (en) 1987-06-09 1989-01-02 Sentron V O F SUBSTRATE PROVIDED WITH A BLOOD COMPATIBLE SURFACE OBTAINED BY COUPLING WITH THE SURFACE OF A PHYSIOLOGICALLY ACTIVE SUBSTANCE WITH AN INHIBITORY INFLUENCE ON THE FORMATION OF BLOOD CLOTS AND / OR CONTAINED FROM HARMFOLIC CIRCULARS.
US4969458A (en) 1987-07-06 1990-11-13 Medtronic, Inc. Intracoronary stent and method of simultaneous angioplasty and stent implant
US5263984A (en) 1987-07-20 1993-11-23 Regen Biologics, Inc. Prosthetic ligaments
US5472702A (en) 1987-08-26 1995-12-05 United States Surgical Corporation Sterilization of growth factors
US5131908A (en) 1987-09-01 1992-07-21 Herbert Dardik Tubular prosthesis for vascular reconstructive surgery and process for preparing same
US4990131A (en) 1987-09-01 1991-02-05 Herbert Dardik Tubular prostheses for vascular reconstructive surgery and process for preparing same
US5047020A (en) 1987-09-14 1991-09-10 Baxter International Inc. Ionic heparin coating
US5133732A (en) 1987-10-19 1992-07-28 Medtronic, Inc. Intravascular stent
US4886062A (en) 1987-10-19 1989-12-12 Medtronic, Inc. Intravascular radially expandable stent and method of implant
US5192307A (en) 1987-12-08 1993-03-09 Wall W Henry Angioplasty stent
US5266073A (en) 1987-12-08 1993-11-30 Wall W Henry Angioplasty stent
US4916193A (en) 1987-12-17 1990-04-10 Allied-Signal Inc. Medical devices fabricated totally or in part from copolymers of recurring units derived from cyclic carbonates and lactides
US5185408A (en) 1987-12-17 1993-02-09 Allied-Signal Inc. Medical devices fabricated totally or in part from copolymers of recurring units derived from cyclic carbonates and lactides
US5019096A (en) 1988-02-11 1991-05-28 Trustees Of Columbia University In The City Of New York Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same
US4950256A (en) 1988-04-07 1990-08-21 Luther Medical Products, Inc. Non-thrombogenic intravascular time release catheter
DE68927479T2 (en) 1988-05-02 1997-04-03 Phanos Tech Inc CONNECTIONS, COMPOSITIONS AND METHOD FOR BINDING ORGANIC AFFECTION SUBSTANCES TO SURFACE MEMBRANES OF BIOPARTICLES
DE3817172A1 (en) 1988-05-20 1989-11-30 Kugelfischer G Schaefer & Co GASKET FOR A BALL SCREW DRIVE
US4994298A (en) 1988-06-07 1991-02-19 Biogold Inc. Method of making a biocompatible prosthesis
US5182317A (en) 1988-06-08 1993-01-26 Cardiopulmonics, Inc. Multifunctional thrombo-resistant coatings and methods of manufacture
US5338770A (en) 1988-06-08 1994-08-16 Cardiopulmonics, Inc. Gas permeable thrombo-resistant coatings and methods of manufacture
US5262451A (en) 1988-06-08 1993-11-16 Cardiopulmonics, Inc. Multifunctional thrombo-resistant coatings and methods of manufacture
US4998923A (en) 1988-08-11 1991-03-12 Advanced Cardiovascular Systems, Inc. Steerable dilatation catheter
US5328471A (en) 1990-02-26 1994-07-12 Endoluminal Therapeutics, Inc. Method and apparatus for treatment of focal disease in hollow tubular organs and other tissue lumens
US5092877A (en) 1988-09-01 1992-03-03 Corvita Corporation Radially expandable endoprosthesis
US5019090A (en) 1988-09-01 1991-05-28 Corvita Corporation Radially expandable endoprosthesis and the like
US5226913A (en) 1988-09-01 1993-07-13 Corvita Corporation Method of making a radially expandable prosthesis
US5053048A (en) 1988-09-22 1991-10-01 Cordis Corporation Thromboresistant coating
CA1322628C (en) 1988-10-04 1993-10-05 Richard A. Schatz Expandable intraluminal graft
US5162430A (en) 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US4856516A (en) 1989-01-09 1989-08-15 Cordis Corporation Endovascular stent apparatus and method
CH678393A5 (en) 1989-01-26 1991-09-13 Ulrich Prof Dr Med Sigwart
US5163958A (en) 1989-02-02 1992-11-17 Cordis Corporation Carbon coated tubular endoprosthesis
US6146358A (en) 1989-03-14 2000-11-14 Cordis Corporation Method and apparatus for delivery of therapeutic agent
US5041100A (en) 1989-04-28 1991-08-20 Cordis Corporation Catheter and hydrophilic, friction-reducing coating thereon
US4990155A (en) 1989-05-19 1991-02-05 Wilkoff Howard M Surgical stent method and apparatus
US4994071A (en) 1989-05-22 1991-02-19 Cordis Corporation Bifurcating stent apparatus and method
US5045072A (en) 1989-06-13 1991-09-03 Cordis Corporation Catheter having highly radiopaque, flexible tip
US5171262A (en) 1989-06-15 1992-12-15 Cordis Corporation Non-woven endoprosthesis
US5015253A (en) 1989-06-15 1991-05-14 Cordis Corporation Non-woven endoprosthesis
US5272012A (en) 1989-06-23 1993-12-21 C. R. Bard, Inc. Medical apparatus having protective, lubricious coating
US5196404B1 (en) 1989-08-18 1996-09-10 Biogen Inc Inhibitors of thrombin
US5292331A (en) 1989-08-24 1994-03-08 Applied Vascular Engineering, Inc. Endovascular support device
CA2026604A1 (en) 1989-10-02 1991-04-03 Rodney G. Wolff Articulated stent
US5213898A (en) 1989-10-12 1993-05-25 Norsk Hydro A.S. Process for the preparation of surface modified solid substrates
US5049403A (en) 1989-10-12 1991-09-17 Horsk Hydro A.S. Process for the preparation of surface modified solid substrates
US5035706A (en) 1989-10-17 1991-07-30 Cook Incorporated Percutaneous stent and method for retrieval thereof
US5176660A (en) 1989-10-23 1993-01-05 Cordis Corporation Catheter having reinforcing strands
US5123913A (en) 1989-11-27 1992-06-23 Wilk Peter J Suture device
US5059166A (en) 1989-12-11 1991-10-22 Medical Innovative Technologies R & D Limited Partnership Intra-arterial stent with the capability to inhibit intimal hyperplasia
KR920000459B1 (en) 1989-12-13 1992-01-14 재단법인 한국화학연구소 Artificial vascular tube
US5304121A (en) 1990-12-28 1994-04-19 Boston Scientific Corporation Drug delivery system making use of a hydrogel polymer coating
US5439446A (en) 1994-06-30 1995-08-08 Boston Scientific Corporation Stent and therapeutic delivery system
US5822601A (en) 1989-12-29 1998-10-13 Packard Bell Nec Apparatus to allow a CPU to control the relocation of code blocks for other CPUs
US5049132A (en) 1990-01-08 1991-09-17 Cordis Corporation Balloon catheter for delivering therapeutic agents
EP0441516B1 (en) 1990-02-08 1995-03-29 Howmedica Inc. Inflatable stent
NL194941C (en) 1990-02-15 2003-08-04 Cordis Corp Method for applying a physiologically active compound to a substrate surface.
WO1991012779A1 (en) 1990-02-28 1991-09-05 Medtronic, Inc. Intralumenal drug eluting prosthesis
US5545208A (en) 1990-02-28 1996-08-13 Medtronic, Inc. Intralumenal drug eluting prosthesis
US6004346A (en) 1990-02-28 1999-12-21 Medtronic, Inc. Intralumenal drug eluting prosthesis
FR2663733B2 (en) 1990-03-19 1994-07-01 Canovas Gines DEVICE FOR MONITORING THE WEAR AND PRESSURE OF TIRES AND GEOMETRY OF TIRE TRAINS.
FR2660189B1 (en) 1990-03-28 1992-07-31 Lefebvre Jean Marie DEVICE INTENDED TO BE IMPLANTED IN A VESSEL WITH SIDE LEGS WITH ANTAGONIST TEETH.
IL94138A (en) 1990-04-19 1997-03-18 Instent Inc Device for the treatment of constricted fluid conducting ducts
AU7998091A (en) 1990-05-17 1991-12-10 Harbor Medical Devices, Inc. Medical device polymer
US5199951A (en) 1990-05-17 1993-04-06 Wayne State University Method of drug application in a transporting medium to an arterial wall injured during angioplasty
FR2663217B1 (en) 1990-06-15 1992-10-16 Antheor FILTERING DEVICE FOR THE PREVENTION OF EMBOLIES.
US5064435A (en) 1990-06-28 1991-11-12 Schneider (Usa) Inc. Self-expanding prosthesis having stable axial length
US5122154A (en) 1990-08-15 1992-06-16 Rhodes Valentine J Endovascular bypass graft
US5234447A (en) * 1990-08-28 1993-08-10 Robert L. Kaster Side-to-end vascular anastomotic staple apparatus
US5258020A (en) 1990-09-14 1993-11-02 Michael Froix Method of using expandable polymeric stent with memory
US5163952A (en) 1990-09-14 1992-11-17 Michael Froix Expandable polymeric stent with memory and delivery apparatus and method
US5222971A (en) 1990-10-09 1993-06-29 Scimed Life Systems, Inc. Temporary stent and methods for use and manufacture
CA2052981C (en) 1990-10-09 1995-08-01 Cesare Gianturco Percutaneous stent assembly
US5449372A (en) 1990-10-09 1995-09-12 Scimed Lifesystems, Inc. Temporary stent and methods for use and manufacture
US5180366A (en) 1990-10-10 1993-01-19 Woods W T Apparatus and method for angioplasty and for preventing re-stenosis
US5486357A (en) 1990-11-08 1996-01-23 Cordis Corporation Radiofrequency plasma biocompatibility treatment of inside surfaces
US5132108A (en) 1990-11-08 1992-07-21 Cordis Corporation Radiofrequency plasma treated polymeric surfaces having immobilized anti-thrombogenic agents
US5234160A (en) 1990-11-21 1993-08-10 Elopak Systems A.G. Aseptic pour spout seal for flat top end closures
US5632776A (en) 1990-11-22 1997-05-27 Toray Industries, Inc. Implantation materials
US5217483A (en) 1990-11-28 1993-06-08 Numed, Inc. Intravascular radially expandable stent
US5893840A (en) 1991-01-04 1999-04-13 Medtronic, Inc. Releasable microcapsules on balloon catheters
US5178618A (en) 1991-01-16 1993-01-12 Brigham And Womens Hospital Method and device for recanalization of a body passageway
US5354257A (en) 1991-01-29 1994-10-11 Med Institute, Inc. Minimally invasive medical device for providing a radiation treatment
US5135536A (en) 1991-02-05 1992-08-04 Cordis Corporation Endovascular stent and method
US5378475A (en) 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
US5116365A (en) 1991-02-22 1992-05-26 Cordis Corporation Stent apparatus and method for making
WO1992015286A1 (en) 1991-02-27 1992-09-17 Nova Pharmaceutical Corporation Anti-infective and anti-inflammatory releasing systems for medical devices
US5540928A (en) 1991-02-27 1996-07-30 President And Fellows Of Harvard College Extraluminal regulation of the growth and repair of tubular structures in vivo
US5171217A (en) 1991-02-28 1992-12-15 Indiana University Foundation Method for delivery of smooth muscle cell inhibitors
US5254107A (en) 1991-03-06 1993-10-19 Cordis Corporation Catheter having extended braid reinforced transitional tip
TW222650B (en) 1991-04-01 1994-04-21 Dow Corning
US5304200A (en) 1991-05-29 1994-04-19 Cordis Corporation Welded radially expandable endoprosthesis and the like
US5213576A (en) 1991-06-11 1993-05-25 Cordis Corporation Therapeutic porous balloon catheter
US5314472A (en) 1991-10-01 1994-05-24 Cook Incorporated Vascular stent
US5527354A (en) 1991-06-28 1996-06-18 Cook Incorporated Stent formed of half-round wire
USD359802S (en) 1991-06-28 1995-06-27 Cook Incorporated Vascular stent
US5202332A (en) 1991-08-07 1993-04-13 American Home Products Corporation Rapamycin analog as immunosuppressant
US5356433A (en) 1991-08-13 1994-10-18 Cordis Corporation Biocompatible metal surfaces
JP3558293B2 (en) 1991-08-27 2004-08-25 ダイキン工業株式会社 Fluoro rubber coating composition
US5176972A (en) 1991-09-11 1993-01-05 Polaroid Corporation Imaging medium with low refractive index layer
WO1993005825A1 (en) 1991-09-20 1993-04-01 Baxter International Inc. Processes for reducing the thrombogenicity of biomaterials
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5443498A (en) 1991-10-01 1995-08-22 Cook Incorporated Vascular stent and method of making and implanting a vacsular stent
WO1993006792A1 (en) 1991-10-04 1993-04-15 Scimed Life Systems, Inc. Biodegradable drug delivery vascular stent
US5500013A (en) 1991-10-04 1996-03-19 Scimed Life Systems, Inc. Biodegradable drug delivery vascular stent
US5464450A (en) 1991-10-04 1995-11-07 Scimed Lifesystems Inc. Biodegradable drug delivery vascular stent
US5366504A (en) 1992-05-20 1994-11-22 Boston Scientific Corporation Tubular medical prosthesis
US5290305A (en) 1991-10-11 1994-03-01 Kanji Inoue Appliance collapsible for insertion into human organs and capable of resilient restoration
US5387235A (en) 1991-10-25 1995-02-07 Cook Incorporated Expandable transluminal graft prosthesis for repair of aneurysm
US5720776A (en) 1991-10-25 1998-02-24 Cook Incorporated Barb and expandable transluminal graft prosthesis for repair of aneurysm
CA2380683C (en) 1991-10-28 2006-08-08 Advanced Cardiovascular Systems, Inc. Expandable stents and method for making same
US5311884A (en) 1991-11-12 1994-05-17 Ethicon, Inc. Process for making a piezoelectric biomedical device
US5516781A (en) 1992-01-09 1996-05-14 American Home Products Corporation Method of treating restenosis with rapamycin
US5258021A (en) 1992-01-27 1993-11-02 Duran Carlos G Sigmoid valve annuloplasty ring
CA2087132A1 (en) 1992-01-31 1993-08-01 Michael S. Williams Stent capable of attachment within a body lumen
US5405377A (en) 1992-02-21 1995-04-11 Endotech Ltd. Intraluminal stent
PT584347E (en) 1992-03-04 2003-06-30 Cell Therapeutics Inc ENANTIOMERIC HYDROXYLATED XANTIN COMPOUNDS
DE4206843C2 (en) 1992-03-04 1994-03-24 Heraeus Elektrochemie Electrochemical cells for performing electrochemical processes
US5648357A (en) 1992-03-04 1997-07-15 Cell Therapeutics, Inc. Enatiomerically pure hydroxylated xanthine compounds
US5580874A (en) 1992-03-04 1996-12-03 Cell Therapeutics, Inc. Enatiomerically pure hydroxylated xanthine compounds
US5510077A (en) 1992-03-19 1996-04-23 Dinh; Thomas Q. Method of making an intraluminal stent
DE69326631T2 (en) 1992-03-19 2000-06-08 Medtronic Inc Intraluminal expansion device
US5591224A (en) 1992-03-19 1997-01-07 Medtronic, Inc. Bioelastomeric stent
US5571166A (en) 1992-03-19 1996-11-05 Medtronic, Inc. Method of making an intraluminal stent
US5599352A (en) 1992-03-19 1997-02-04 Medtronic, Inc. Method of making a drug eluting stent
US5282823A (en) 1992-03-19 1994-02-01 Medtronic, Inc. Intravascular radially expandable stent
US5370683A (en) 1992-03-25 1994-12-06 Cook Incorporated Vascular stent
SE500972C2 (en) 1992-03-30 1994-10-10 Moelnlycke Ab Method and apparatus for manufacturing wound dressings and a wound dressing made by the method
US5306250A (en) 1992-04-02 1994-04-26 Indiana University Foundation Method and apparatus for intravascular drug delivery
FR2689388B1 (en) 1992-04-07 1999-07-16 Celsa Lg PERFECTIONALLY RESORBABLE BLOOD FILTER.
US5288711A (en) 1992-04-28 1994-02-22 American Home Products Corporation Method of treating hyperproliferative vascular disease
CA2094858C (en) 1992-04-28 2004-06-15 Robert D. Mitchell Method of treating hyperproliferative vascular disease
US5368566A (en) 1992-04-29 1994-11-29 Cardiovascular Dynamics, Inc. Delivery and temporary stent catheter having a reinforced perfusion lumen
WO1995014500A1 (en) 1992-05-01 1995-06-01 Beth Israel Hospital A stent
US5354308A (en) 1992-05-01 1994-10-11 Beth Israel Hospital Association Metal wire stent
US5383928A (en) 1992-06-10 1995-01-24 Emory University Stent sheath for local drug delivery
US5342387A (en) 1992-06-18 1994-08-30 American Biomed, Inc. Artificial support for a blood vessel
CA2138026C (en) 1992-06-22 2003-09-09 Eckard Weber Novel 1,4-dihydroquinoxaline-2,3-diones and uses therefor as glycine receptor antagonists
US5496365A (en) 1992-07-02 1996-03-05 Sgro; Jean-Claude Autoexpandable vascular endoprosthesis
DE4222380A1 (en) 1992-07-08 1994-01-13 Ernst Peter Prof Dr M Strecker Endoprosthesis implantable percutaneously in a patient's body
US5283257A (en) 1992-07-10 1994-02-01 The Board Of Trustees Of The Leland Stanford Junior University Method of treating hyperproliferative vascular disease
DE4226100A1 (en) 1992-08-07 1994-02-10 Stihl Maschf Andreas Voltage supply for microprocessor used in ignition circuit of two-stroke IC engine - has generator with permanent magnet disk rotor and inductor feeding thyristor to microprocessor in parallel with capacitor
US5256790A (en) 1992-08-13 1993-10-26 American Home Products Corporation 27-hydroxyrapamycin and derivatives thereof
US5382261A (en) 1992-09-01 1995-01-17 Expandable Grafts Partnership Method and apparatus for occluding vessels
US5342621A (en) 1992-09-15 1994-08-30 Advanced Cardiovascular Systems, Inc. Antithrombogenic surface
CA2106034A1 (en) 1992-09-24 1994-03-25 Ralph J. Russo 21-norrapamycin
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6306421B1 (en) 1992-09-25 2001-10-23 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
GB9221220D0 (en) 1992-10-09 1992-11-25 Sandoz Ag Organic componds
EP0597593A1 (en) 1992-10-30 1994-05-18 Medtronic, Inc. Thromboresistant articles
US5449382A (en) 1992-11-04 1995-09-12 Dayton; Michael P. Minimally invasive bioactivated endoprosthesis for vessel repair
US5578075B1 (en) 1992-11-04 2000-02-08 Daynke Res Inc Minimally invasive bioactivated endoprosthesis for vessel repair
US5383853A (en) 1992-11-12 1995-01-24 Medtronic, Inc. Rapid exchange catheter
US5780476A (en) 1992-11-16 1998-07-14 Cell Therapeutics, Inc. Hydroxyl-containing xanthine compounds
US5342348A (en) 1992-12-04 1994-08-30 Kaplan Aaron V Method and device for treating and enlarging body lumens
US5336518A (en) 1992-12-11 1994-08-09 Cordis Corporation Treatment of metallic surfaces using radiofrequency plasma deposition and chemical attachment of bioactive agents
BE1006440A3 (en) 1992-12-21 1994-08-30 Dereume Jean Pierre Georges Em Luminal endoprosthesis AND METHOD OF PREPARATION.
US5443458A (en) 1992-12-22 1995-08-22 Advanced Cardiovascular Systems, Inc. Multilayered biodegradable stent and method of manufacture
FR2699809B1 (en) 1992-12-28 1995-02-17 Celsa Lg Device which can selectively constitute a temporary blood filter.
US5540703A (en) 1993-01-06 1996-07-30 Smith & Nephew Richards Inc. Knotted cable attachment apparatus formed of braided polymeric fibers
US5429634A (en) 1993-09-09 1995-07-04 Pdt Systems Biogenic implant for drug delivery and method
US5419760A (en) 1993-01-08 1995-05-30 Pdt Systems, Inc. Medicament dispensing stent for prevention of restenosis of a blood vessel
US5308641A (en) 1993-01-19 1994-05-03 Medtronic, Inc. Biocompatibility of solid surfaces
US5229172A (en) 1993-01-19 1993-07-20 Medtronic, Inc. Modification of polymeric surface by graft polymerization
US5350800A (en) 1993-01-19 1994-09-27 Medtronic, Inc. Method for improving the biocompatibility of solid surfaces
US5370691A (en) 1993-01-26 1994-12-06 Target Therapeutics, Inc. Intravascular inflatable stent
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
CA2114988A1 (en) * 1993-02-05 1994-08-06 Matthew O'boyle Ultrasonic angioplasty balloon catheter
US5252579A (en) 1993-02-16 1993-10-12 American Home Products Corporation Macrocyclic immunomodulators
US5976534A (en) 1993-02-25 1999-11-02 Zymogenetics, Inc. Inhibition of intimal hyperplasia using antibodies to PDGF receptors and heparin
US5308862A (en) 1993-03-05 1994-05-03 Boehringer Mannheim Pharmaceuticals Corporation - Smithkline Beecham Corp., Ltd. Partnership No. 1 Use of, and method of treatment using, carbazolyl-(4)-oxypropanolamine compounds for inhibition of smooth muscle cell proliferation
JPH08507715A (en) 1993-03-18 1996-08-20 シーダーズ サイナイ メディカル センター Drug-inducing and releasable polymeric coatings for bioartificial components
BE1006819A7 (en) 1993-03-24 1994-12-13 Dsb Nv Polyurethane coated prostheses (stents) FOR THE TREATMENT OF VESSEL CHOKES.
US5474563A (en) 1993-03-25 1995-12-12 Myler; Richard Cardiovascular stent and retrieval apparatus
US5607463A (en) 1993-03-30 1997-03-04 Medtronic, Inc. Intravascular medical device
US5670506A (en) 1993-04-05 1997-09-23 Cell Therapeutics, Inc. Halogen, isothiocyanate or azide substituted xanthines
US5985307A (en) 1993-04-14 1999-11-16 Emory University Device and method for non-occlusive localized drug delivery
US5523092A (en) 1993-04-14 1996-06-04 Emory University Device for local drug delivery and methods for using the same
US5399352A (en) 1993-04-14 1995-03-21 Emory University Device for local drug delivery and methods for using the same
EP0695152A1 (en) 1993-04-23 1996-02-07 Schneider (Usa) Inc. Covered stent and stent delivery device
US5504091A (en) 1993-04-23 1996-04-02 American Home Products Corporation Biotin esters of rapamycin
US5441515A (en) 1993-04-23 1995-08-15 Advanced Cardiovascular Systems, Inc. Ratcheting stent
US5824048A (en) 1993-04-26 1998-10-20 Medtronic, Inc. Method for delivering a therapeutic substance to a body lumen
US5464650A (en) 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
EP0696185B1 (en) 1993-04-28 1998-08-12 Focal, Inc. Apparatus, product and use related to intraluminal photothermoforming
DE69435137D1 (en) 1993-05-13 2008-10-16 Poniard Pharmaceuticals Inc PREVENTION AND TREATMENT OF PATHOLOGIES ASSOCIATED WITH AN ABNORMAL PROLIFERATION GLATTER MUSCLE CELLS
DE4417528C2 (en) † 1993-05-21 1997-05-28 Biovision Gmbh Anastomosis device
CH686761A5 (en) 1993-05-27 1996-06-28 Sandoz Ag Pharmaceutical formulations.
JPH07498A (en) 1993-06-02 1995-01-06 Uchida Yasunari Bone inducing material
JPH0767895A (en) 1993-06-25 1995-03-14 Sumitomo Electric Ind Ltd Antimicrobial artificial blood vessel and suture yarn for antimicrobial operation
US5344402A (en) 1993-06-30 1994-09-06 Cardiovascular Dynamics, Inc. Low profile perfusion catheter
US5937051A (en) 1993-07-08 1999-08-10 Teknekron Infoswitch Corporation Method and system for transferring calls and call-related data between a plurality of call centers
US5411549A (en) 1993-07-13 1995-05-02 Scimed Life Systems, Inc. Selectively expandable, retractable and removable stent
ATE154757T1 (en) † 1993-07-19 1997-07-15 Angiotech Pharm Inc ANTI-ANGIogenic AGENTS AND METHODS OF USE THEREOF
US5716981A (en) 1993-07-19 1998-02-10 Angiogenesis Technologies, Inc. Anti-angiogenic compositions and methods of use
JP3220331B2 (en) 1993-07-20 2001-10-22 エチコン・インコーポレーテツド Absorbable liquid copolymers for parenteral administration
WO1995003010A1 (en) 1993-07-23 1995-02-02 Cook Incorporated A flexible stent having a pattern formed from a sheet of material
AU7476894A (en) 1993-07-29 1995-02-28 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Method of treating atherosclerosis or restenosis using microtubule stabilizing agent
US5387680A (en) 1993-08-10 1995-02-07 American Home Products Corporation C-22 ring stabilized rapamycin derivatives
US5441947A (en) 1993-08-25 1995-08-15 Eli Lilly And Company Methods of inhibiting vascular restenosis
US5380299A (en) 1993-08-30 1995-01-10 Med Institute, Inc. Thrombolytic treated intravascular medical device
EP0670738A1 (en) 1993-09-24 1995-09-13 Baxter International Inc. Methods for enhancing vascularization of implant devices
EP0746236B1 (en) 1993-10-01 2003-08-20 Boston Scientific Corporation Improved vena cava filter
US5378836A (en) 1993-10-08 1995-01-03 American Home Products Corporation Rapamycin oximes and hydrazones
US5391730A (en) 1993-10-08 1995-02-21 American Home Products Corporation Phosphorylcarbamates of rapamycin and oxime derivatives thereof
WO1995010989A1 (en) 1993-10-19 1995-04-27 Scimed Life Systems, Inc. Intravascular stent pump
US5389106A (en) 1993-10-29 1995-02-14 Numed, Inc. Impermeable expandable intravascular stent
US5385908A (en) 1993-11-22 1995-01-31 American Home Products Corporation Hindered esters of rapamycin
US5385910A (en) 1993-11-22 1995-01-31 American Home Products Corporation Gem-distributed esters of rapamycin
US5385909A (en) 1993-11-22 1995-01-31 American Home Products Corporation Heterocyclic esters of rapamycin
US5393772A (en) 1993-11-24 1995-02-28 Boehringer Mannheim Pharmaceuticals Corporation Use of, and method of treatment using, hydroxycarbazole compounds for inhibition of smooth muscle migration and proliferation
US5792106A (en) 1993-12-02 1998-08-11 Scimed Life Systems, Inc. In situ stent forming catheter
US5464540A (en) 1993-12-09 1995-11-07 Bend Research, Inc. Pervaporation by countercurrent condensable sweep
JPH07175535A (en) 1993-12-16 1995-07-14 Nec Corp Power circuit for fet amplifier
ATE191218T1 (en) 1993-12-17 2000-04-15 Novartis Ag RAPAMYCIN DERIVATIVES AS IMMUNOSUPPRESSORS
JP2703510B2 (en) 1993-12-28 1998-01-26 アドヴァンスド カーディオヴァスキュラー システムズ インコーポレーテッド Expandable stent and method of manufacturing the same
US5389639A (en) 1993-12-29 1995-02-14 American Home Products Company Amino alkanoic esters of rapamycin
US5519042A (en) 1994-01-13 1996-05-21 Hoechst Aktiengesellschaft Method of treating hyperproliferative vascular disease
WO1995019796A1 (en) 1994-01-21 1995-07-27 Brown University Research Foundation Biocompatible implants
US5403341A (en) 1994-01-24 1995-04-04 Solar; Ronald J. Parallel flow endovascular stent and deployment apparatus therefore
US5609627A (en) 1994-02-09 1997-03-11 Boston Scientific Technology, Inc. Method for delivering a bifurcated endoluminal prosthesis
US5443477A (en) 1994-02-10 1995-08-22 Stentco, Inc. Apparatus and method for deployment of radially expandable stents by a mechanical linkage
US5643312A (en) 1994-02-25 1997-07-01 Fischell Robert Stent having a multiplicity of closed circular structures
US5441516A (en) 1994-03-03 1995-08-15 Scimed Lifesystems Inc. Temporary stent
IL112873A (en) 1994-03-08 2005-03-20 Wyeth Corp Rapamycin-fkbp12 binding proteins, their isolation and their use
US5556413A (en) 1994-03-11 1996-09-17 Advanced Cardiovascular Systems, Inc. Coiled stent with locking ends
US5843120A (en) 1994-03-17 1998-12-01 Medinol Ltd. Flexible-expandable stent
US5449373A (en) 1994-03-17 1995-09-12 Medinol Ltd. Articulated stent
US5807861A (en) 1994-03-24 1998-09-15 Cell Therapeutics, Inc. Amine substituted xanthinyl compounds
US5525610A (en) 1994-03-31 1996-06-11 American Home Products Corporation 42-Epi-rapamycin and pharmaceutical compositions thereof
US5362718A (en) 1994-04-18 1994-11-08 American Home Products Corporation Rapamycin hydroxyesters
JP2825452B2 (en) 1994-04-25 1998-11-18 アドヴァンスド カーディオヴァスキュラー システムズ インコーポレーテッド Radiopak stent marker
CA2188563C (en) 1994-04-29 2005-08-02 Andrew W. Buirge Stent with collagen
US5464580A (en) 1994-06-01 1995-11-07 Ethicon, Inc. Process of sterilization
US5463048A (en) 1994-06-14 1995-10-31 American Home Products Corporation Rapamycin amidino carbamates
US5629077A (en) 1994-06-27 1997-05-13 Advanced Cardiovascular Systems, Inc. Biodegradable mesh and film stent
CA2136576C (en) 1994-06-27 2005-03-08 Bernard Cohen Improved nonwoven barrier and method of making the same
DE4422336A1 (en) 1994-06-27 1996-01-04 Basf Ag Use of leukotriarylmethanes for marking hydrocarbons
US5397355A (en) 1994-07-19 1995-03-14 Stentco, Inc. Intraluminal stent
US5788979A (en) 1994-07-22 1998-08-04 Inflow Dynamics Inc. Biodegradable coating with inhibitory properties for application to biocompatible materials
US5656121A (en) 1994-08-19 1997-08-12 Minnesota Mining And Manufacturing Company Method of making multi-layer composites having a fluoropolymer layer
US5660873A (en) 1994-09-09 1997-08-26 Bioseal, Limited Liability Corporaton Coating intraluminal stents
US5891108A (en) 1994-09-12 1999-04-06 Cordis Corporation Drug delivery stent
US5649977A (en) 1994-09-22 1997-07-22 Advanced Cardiovascular Systems, Inc. Metal reinforced polymer stent
US5749203A (en) 1994-09-23 1998-05-12 Kimberly-Clark Corporation Method of packaging a medical article
WO1996011720A1 (en) 1994-10-17 1996-04-25 Kabushikikaisha Igaki Iryo Sekkei Drug-releasing stent
US5603894A (en) 1994-10-31 1997-02-18 Abbott Laboratories Method of sterilizing a pharmaceutical composition
EP0790810B1 (en) 1994-11-09 2004-04-28 Endotex Interventional Systems, Inc. Kit of delivery catheter and graft for aneurysm repair
US5707385A (en) 1994-11-16 1998-01-13 Advanced Cardiovascular Systems, Inc. Drug loaded elastic membrane and method for delivery
US5491231A (en) 1994-11-28 1996-02-13 American Home Products Corporation Hindered N-oxide esters of rapamycin
US5665591A (en) 1994-12-06 1997-09-09 Trustees Of Boston University Regulation of smooth muscle cell proliferation
US5563145A (en) 1994-12-07 1996-10-08 American Home Products Corporation Rapamycin 42-oximes and hydroxylamines
US5637113A (en) 1994-12-13 1997-06-10 Advanced Cardiovascular Systems, Inc. Polymer film for wrapping a stent structure
US5569197A (en) 1994-12-21 1996-10-29 Schneider (Usa) Inc Drug delivery guidewire
US5986049A (en) 1994-12-30 1999-11-16 Zymogenetics, Inc. Purified thrombopoietin and method of making it
US6254618B1 (en) 1995-01-18 2001-07-03 Pepi Dakov Connector for hollow anatomical organs
NL9500094A (en) 1995-01-19 1996-09-02 Industrial Res Bv Y-shaped stent and method of deployment.
US5827734A (en) 1995-01-20 1998-10-27 University Of Washington Materials and methods for determining ob protein in a biological sample
US5858967A (en) 1995-01-20 1999-01-12 University Of Washington Appetite supression factor and related methods
US5575818A (en) 1995-02-14 1996-11-19 Corvita Corporation Endovascular stent with locking ring
US6179817B1 (en) 1995-02-22 2001-01-30 Boston Scientific Corporation Hybrid coating for medical devices
US5904697A (en) * 1995-02-24 1999-05-18 Heartport, Inc. Devices and methods for performing a vascular anastomosis
US5695504A (en) † 1995-02-24 1997-12-09 Heartport, Inc. Devices and methods for performing a vascular anastomosis
DE69622231T2 (en) 1995-03-01 2002-12-05 Scimed Life Systems Inc LENGTHFLEXIBLE AND EXPANDABLE STENT
US5591197A (en) 1995-03-14 1997-01-07 Advanced Cardiovascular Systems, Inc. Expandable stent forming projecting barbs and method for deploying
US5571191A (en) 1995-03-16 1996-11-05 Fitz; William R. Artificial facet joint
CA2171896C (en) 1995-03-17 2007-05-15 Scott C. Anderson Multi-anchor stent
CA2215731A1 (en) 1995-03-20 1996-09-26 Allergan Use of retinoids for the manufacture of a medicament for the treatment of restenosis
US6306144B1 (en) 1996-11-01 2001-10-23 Scimed Life Systems, Inc. Selective coating of a balloon catheter with lubricious material for stent deployment
US5605696A (en) 1995-03-30 1997-02-25 Advanced Cardiovascular Systems, Inc. Drug loaded polymeric material and method of manufacture
US5709713A (en) 1995-03-31 1998-01-20 Cardiovascular Concepts, Inc. Radially expansible vascular prosthesis having reversible and other locking structures
ES2119527T5 (en) 1995-04-01 2006-11-16 Variomed Ag STENT DEVICE FOR TRANSLUMINAL IMPLEMENTATION IN HOLLOW ORGANS.
US6099562A (en) 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
US5837313A (en) 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
CA2216943C (en) 1995-04-19 2003-06-17 Schneider (Usa) Inc. Drug release coated stent
US20020091433A1 (en) 1995-04-19 2002-07-11 Ni Ding Drug release coated stent
US6120536A (en) 1995-04-19 2000-09-19 Schneider (Usa) Inc. Medical devices with long term non-thrombogenic coatings
US5667523A (en) 1995-04-28 1997-09-16 Impra, Inc. Dual supported intraluminal graft
US5628786A (en) 1995-05-12 1997-05-13 Impra, Inc. Radially expandable vascular graft with resistance to longitudinal compression and method of making same
US5622975A (en) 1995-06-01 1997-04-22 Eli Lilly And Company Methods for inhibiting vascular smooth muscle cell migration
US5603722A (en) 1995-06-06 1997-02-18 Quanam Medical Corporation Intravascular stent
US5674242A (en) 1995-06-06 1997-10-07 Quanam Medical Corporation Endoprosthetic device with therapeutic compound
US5820917A (en) 1995-06-07 1998-10-13 Medtronic, Inc. Blood-contacting medical device and method
US5710174A (en) 1995-06-07 1998-01-20 Zymo Genetics, Inc. Factor XIIIA inhibitor
US5618837A (en) 1995-06-07 1997-04-08 Zymogenetics, Inc. PDGF antagonists III
US5679404A (en) 1995-06-07 1997-10-21 Saint-Gobain/Norton Industrial Ceramics Corporation Method for depositing a substance with temperature control
US6187757B1 (en) 1995-06-07 2001-02-13 Ariad Pharmaceuticals, Inc. Regulation of biological events using novel compounds
US5609629A (en) 1995-06-07 1997-03-11 Med Institute, Inc. Coated implantable medical device
US5744587A (en) 1995-06-07 1998-04-28 Zymogenetics, Inc. Method for purifying thrombopoietin
US5798374A (en) 1995-06-07 1998-08-25 Sugen Inc. Methods of inhibiting phosphatase activity and treatment of disorders associated therewith
CA2178541C (en) 1995-06-07 2009-11-24 Neal E. Fearnot Implantable medical device
US5786171A (en) 1995-06-22 1998-07-28 President And Fellows Of Harvard University Aortic preferentially expressed gene and uses thereof
JP3195363B2 (en) 1995-06-30 2001-08-06 ザイモジェネティクス，インコーポレイティド 4- [2- (N-2-carboxamidoindole) aminoethyl] benzenesulfonamide or sulfonylurea as PDGF antagonist
US5877224A (en) 1995-07-28 1999-03-02 Rutgers, The State University Of New Jersey Polymeric drug formulations
US5679659A (en) 1995-08-22 1997-10-21 Medtronic, Inc. Method for making heparinized biomaterials
US5607475A (en) 1995-08-22 1997-03-04 Medtronic, Inc. Biocompatible medical article and method
US5672638A (en) 1995-08-22 1997-09-30 Medtronic, Inc. Biocompatability for solid surfaces
US6168604B1 (en) 1995-10-06 2001-01-02 Metamorphic Surgical Devices, Llc Guide wire device for removing solid objects from body canals
US5669924A (en) 1995-10-26 1997-09-23 Shaknovich; Alexander Y-shuttle stent assembly for bifurcating vessels and method of using the same
US5574059A (en) 1995-10-27 1996-11-12 Cornell Research Foundation, Inc. Treating disorders mediated by vascular smooth muscle cell proliferation
US5733920A (en) 1995-10-31 1998-03-31 Mitotix, Inc. Inhibitors of cyclin dependent kinases
US5702669A (en) 1995-12-21 1997-12-30 Green; Edward Francis Apparatus method for sterilization using ethylene oxide
US5780462A (en) 1995-12-27 1998-07-14 American Home Products Corporation Water soluble rapamycin esters
US6203569B1 (en) 1996-01-04 2001-03-20 Bandula Wijay Flexible stent
DE69735530T2 (en) 1996-01-04 2006-08-17 Chuter, Timothy A.M. Dr., Atherton FLAT WIRE STENT
US5980553A (en) 1996-12-20 1999-11-09 Cordis Corporation Axially flexible stent
CN1304058C (en) 1996-03-12 2007-03-14 Pg－Txl有限公司 Water soluble paclitaxel prodrugs
US6441025B2 (en) 1996-03-12 2002-08-27 Pg-Txl Company, L.P. Water soluble paclitaxel derivatives
US6334871B1 (en) 1996-03-13 2002-01-01 Medtronic, Inc. Radiopaque stent markers
IL117472A0 (en) 1996-03-13 1996-07-23 Instent Israel Ltd Radiopaque stent markers
CA2199890C (en) 1996-03-26 2002-02-05 Leonard Pinchuk Stents and stent-grafts having enhanced hoop strength and methods of making the same
GB9606452D0 (en) 1996-03-27 1996-06-05 Sandoz Ltd Organic compounds
US5824042A (en) 1996-04-05 1998-10-20 Medtronic, Inc. Endoluminal prostheses having position indicating markers
US5713949A (en) 1996-08-06 1998-02-03 Jayaraman; Swaminathan Microporous covered stents and method of coating
DE19614160A1 (en) 1996-04-10 1997-10-16 Variomed Ag Stent for transluminal implantation in hollow organs
US5932299A (en) 1996-04-23 1999-08-03 Katoot; Mohammad W. Method for modifying the surface of an object
US5728420A (en) 1996-08-09 1998-03-17 Medtronic, Inc. Oxidative method for attachment of glycoproteins to surfaces of medical devices
UA58485C2 (en) 1996-05-03 2003-08-15 Медінол Лтд. Method for manufacture of bifurcated stent (variants) and bifurcated stent (variants)
US5951586A (en) 1996-05-15 1999-09-14 Medtronic, Inc. Intraluminal stent
WO1997043307A1 (en) 1996-05-16 1997-11-20 Warner-Lambert Company Compounds inhibiting the association of the pdgf receptor and phosphatidylinositol 3-kinase and their use
US5876433A (en) 1996-05-29 1999-03-02 Ethicon, Inc. Stent and method of varying amounts of heparin coated thereon to control treatment
US5697971A (en) 1996-06-11 1997-12-16 Fischell; Robert E. Multi-cell stent with cells having differing characteristics
US5676670A (en) 1996-06-14 1997-10-14 Beth Israel Deaconess Medical Center Catheter apparatus and method for creating a vascular bypass in-vivo
NL1003497C2 (en) 1996-07-03 1998-01-07 Cordis Europ Catheter with temporary vena-cava filter.
US5928279A (en) * 1996-07-03 1999-07-27 Baxter International Inc. Stented, radially expandable, tubular PTFE grafts
US5820918A (en) 1996-07-11 1998-10-13 Hercules Incorporated Medical devices containing in-situ generated medical compounds
CA2211249C (en) 1996-07-24 2007-07-17 Cordis Corporation Balloon catheter and methods of use
US6245026B1 (en) 1996-07-29 2001-06-12 Farallon Medsystems, Inc. Thermography catheter
US5924997A (en) 1996-07-29 1999-07-20 Campbell; Thomas Henderson Catheter and method for the thermal mapping of hot spots in vascular lesions of the human body
US5728150A (en) 1996-07-29 1998-03-17 Cardiovascular Dynamics, Inc. Expandable microporous prosthesis
US5959075A (en) 1996-08-02 1999-09-28 Zymogenetics, Inc. Testis-specific insulin homolog polypeptides
US5922730A (en) 1996-09-09 1999-07-13 American Home Products Corporation Alkylated rapamycin derivatives
US6565581B1 (en) 1996-09-16 2003-05-20 Origin Medsystems, Inc. Apparatus and method for performing an anastomosis
US5868763A (en) 1996-09-16 1999-02-09 Guidant Corporation Means and methods for performing an anastomosis
US5722982A (en) 1996-09-26 1998-03-03 University Technology Corporation Strabismus surgery apparatus and method
US6387121B1 (en) 1996-10-21 2002-05-14 Inflow Dynamics Inc. Vascular and endoluminal stents with improved coatings
US5833651A (en) 1996-11-08 1998-11-10 Medtronic, Inc. Therapeutic intraluminal stents
ZA9710342B (en) 1996-11-25 1998-06-10 Alza Corp Directional drug delivery stent and method of use.
US5807743A (en) 1996-12-03 1998-09-15 Ribozyme Pharmaceuticals, Inc. Interleukin-2 receptor gamma-chain ribozymes
US5980972A (en) 1996-12-20 1999-11-09 Schneider (Usa) Inc Method of applying drug-release coatings
US5972024A (en) 1996-12-24 1999-10-26 Metacardia, Inc. Suture-staple apparatus and method
US5843166A (en) 1997-01-17 1998-12-01 Meadox Medicals, Inc. Composite graft-stent having pockets for accomodating movement
EP0968013B1 (en) * 1997-02-20 2005-10-19 Cook Incorporated Coated implantable medical device
CN1311577C (en) 1997-02-28 2007-04-18 北美埃尔夫爱托化学股份有限公司 Copolymers of vinylidene fluoride and hexafluoropropllene having reduced extractable content and improved solution clarity
US5962516A (en) 1997-02-28 1999-10-05 Pharmagenesis, Inc. Immunosuppressive compounds and methods
US6025414A (en) 1997-02-28 2000-02-15 Jeffery S. Rich Heat moldable composition
US5858990A (en) 1997-03-04 1999-01-12 St. Elizabeth's Medical Center Fas ligand compositions for treatment of proliferative disorders
US20020133222A1 (en) 1997-03-05 2002-09-19 Das Gladwin S. Expandable stent having a plurality of interconnected expansion modules
US5827324A (en) 1997-03-06 1998-10-27 Scimed Life Systems, Inc. Distal protection device
US6152946A (en) 1998-03-05 2000-11-28 Scimed Life Systems, Inc. Distal protection device and method
US5814064A (en) 1997-03-06 1998-09-29 Scimed Life Systems, Inc. Distal protection device
US5912225A (en) † 1997-04-14 1999-06-15 Johns Hopkins Univ. School Of Medicine Biodegradable poly (phosphoester-co-desaminotyrosyl L-tyrosine ester) compounds, compositions, articles and methods for making and using the same
US6240616B1 (en) 1997-04-15 2001-06-05 Advanced Cardiovascular Systems, Inc. Method of manufacturing a medicated porous metal prosthesis
US5843172A (en) 1997-04-15 1998-12-01 Advanced Cardiovascular Systems, Inc. Porous medicated stent
US6273913B1 (en) * 1997-04-18 2001-08-14 Cordis Corporation Modified stent useful for delivery of drugs along stent strut
WO1998047447A1 (en) 1997-04-23 1998-10-29 Dubrul William R Bifurcated stent and distal protection system
US5879697A (en) 1997-04-30 1999-03-09 Schneider Usa Inc Drug-releasing coatings for medical devices
US5741327A (en) 1997-05-06 1998-04-21 Global Therapeutics, Inc. Surgical stent featuring radiopaque markers
ES2285770T3 (en) 1997-05-12 2007-11-16 Metabolix, Inc. POLYHYDROXIALCANOATE FOR LIVE APPLICATIONS.
US6730103B2 (en) 1997-05-19 2004-05-04 Pepi Dakov Connector system and methods for cutting and joining hollow anatomical structures
DE69840440D1 (en) 1997-05-30 2009-02-26 Micell Integrated Systems Inc SURFACE TREATMENT
US6165560A (en) 1997-05-30 2000-12-26 Micell Technologies Surface treatment
DE19723723C2 (en) 1997-05-30 1999-05-20 Fraunhofer Ges Forschung Polymer coating for prostheses, implants and body electrodes and processes for their manufacture
US6011082A (en) 1997-06-02 2000-01-04 Pharmacia & Upjohn Ab Process for the modification of elastomers with surface interpreting polymer networks and elastomers formed therefrom
US5916910A (en) 1997-06-04 1999-06-29 Medinox, Inc. Conjugates of dithiocarbamates with pharmacologically active agents and uses therefore
US5800525A (en) 1997-06-04 1998-09-01 Vascular Science, Inc. Blood filter
WO1998056312A1 (en) 1997-06-13 1998-12-17 Scimed Life Systems, Inc. Stents having multiple layers of biodegradable polymeric composition
US6171232B1 (en) 1997-06-26 2001-01-09 Cordis Corporation Method for targeting in vivo nitric oxide release
US5916224A (en) 1997-07-09 1999-06-29 The United States Of America As Represented By The Secretary Of The Army Tendon repair clip implant
US6177272B1 (en) 1997-07-21 2001-01-23 The Regents Of The University Of Michigan Method for treating vascular proliferative diseases with p27 and fusions thereof
US5897911A (en) 1997-08-11 1999-04-27 Advanced Cardiovascular Systems, Inc. Polymer-coated stent structure
US6306166B1 (en) 1997-08-13 2001-10-23 Scimed Life Systems, Inc. Loading and release of water-insoluble drugs
US6159488A (en) 1997-08-14 2000-12-12 Agricultural Research Org. Ministry Of Agriculture (Gov.) Intracoronary stents containing quinazolinone derivatives
US5922022A (en) † 1997-09-04 1999-07-13 Kensey Nash Corporation Bifurcated connector system for coronary bypass grafts and methods of use
ES2290995T3 (en) 1997-09-24 2008-02-16 Med Institute, Inc. RADIALLY EXPANDABLE ENDOPROTESIS.
US6890546B2 (en) 1998-09-24 2005-05-10 Abbott Laboratories Medical devices containing rapamycin analogs
US6015815A (en) 1997-09-26 2000-01-18 Abbott Laboratories Tetrazole-containing rapamycin analogs with shortened half-lives
US5972027A (en) 1997-09-30 1999-10-26 Scimed Life Systems, Inc Porous stent drug delivery system
US6179864B1 (en) 1997-10-13 2001-01-30 Becky Peters-Combs Smoking cessation device and method
US5980565A (en) 1997-10-20 1999-11-09 Iowa-India Investments Company Limited Sandwich stent
US6225346B1 (en) 1997-10-24 2001-05-01 Sugen, Inc. Tyrphostin like compounds
NL1007349C2 (en) 1997-10-24 1999-04-27 Suyker Wilhelmus Joseph Leonardus System for the mechanical production of anastomoses between hollow structures; as well as device and applicator for use therewith.
US5932580A (en) 1997-12-01 1999-08-03 Yissum Research And Development Company Of The Hebrew University Of Jerusalem PDGF receptor kinase inhibitory compounds their preparation and compositions
US6129754A (en) 1997-12-11 2000-10-10 Uni-Cath Inc. Stent for vessel with branch
US6022374A (en) 1997-12-16 2000-02-08 Cardiovasc, Inc. Expandable stent having radiopaque marker and method
GB9726851D0 (en) 1997-12-19 1998-02-18 Zeneca Ltd Human signal transduction serine/threonine kinase
US6129755A (en) 1998-01-09 2000-10-10 Nitinol Development Corporation Intravascular stent having an improved strut configuration
US6623521B2 (en) 1998-02-17 2003-09-23 Md3, Inc. Expandable stent with sliding and locking radial elements
US6140127A (en) 1998-02-18 2000-10-31 Cordis Corporation Method of coating an intravascular stent with an endothelial cell adhesive five amino acid peptide
US6015432A (en) * 1998-02-25 2000-01-18 Cordis Corporation Wire reinforced vascular prosthesis
ES2243050T3 (en) † 1998-03-09 2005-11-16 Ethicon, Inc. ANASTOMOSIS DEVICE.
US6110188A (en) 1998-03-09 2000-08-29 Corvascular, Inc. Anastomosis method
US6425898B1 (en) 1998-03-13 2002-07-30 Cordis Corporation Delivery apparatus for a self-expanding stent
US6887268B2 (en) 1998-03-30 2005-05-03 Cordis Corporation Extension prosthesis for an arterial repair
US7208010B2 (en) 2000-10-16 2007-04-24 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
US6187038B1 (en) * 1998-04-08 2001-02-13 Sulzer Carbomedics Inc. Small bore biologic graft with therapeutic delivery system
US5980566A (en) 1998-04-11 1999-11-09 Alt; Eckhard Vascular and endoluminal stents with iridium oxide coating
US20020099438A1 (en) 1998-04-15 2002-07-25 Furst Joseph G. Irradiated stent coating
US20010029351A1 (en) 1998-04-16 2001-10-11 Robert Falotico Drug combinations and delivery devices for the prevention and treatment of vascular disease
GB2336698A (en) 1998-04-24 1999-10-27 Dialog Corp Plc The Automatic content categorisation of text data files using subdivision to reduce false classification
ES2179646T3 (en) * 1998-04-27 2003-01-16 Surmodics Inc COATING THAT RELEASES A BIOACTIVE AGENT.
JP2002516696A (en) † 1998-05-29 2002-06-11 バイ−パス・インク． Methods and devices for vascular surgery
WO2000056227A1 (en) † 1999-03-19 2000-09-28 By-Pass, Inc. Advanced closure device
US6641593B1 (en) 1998-06-03 2003-11-04 Coalescent Surgical, Inc. Tissue connector apparatus and methods
US6607541B1 (en) 1998-06-03 2003-08-19 Coalescent Surgical, Inc. Tissue connector apparatus and methods
US6254634B1 (en) 1998-06-10 2001-07-03 Surmodics, Inc. Coating compositions
US6740101B2 (en) * 1998-06-10 2004-05-25 Converge Medical, Inc. Sutureless anastomosis systems
US6153252A (en) 1998-06-30 2000-11-28 Ethicon, Inc. Process for coating stents
US6369039B1 (en) 1998-06-30 2002-04-09 Scimed Life Sytems, Inc. High efficiency local drug delivery
NL1009551C2 (en) 1998-07-03 2000-01-07 Cordis Europ Vena cava filter with improvements for controlled ejection.
AU771367B2 (en) 1998-08-20 2004-03-18 Cook Medical Technologies Llc Coated implantable medical device
US6335029B1 (en) 1998-08-28 2002-01-01 Scimed Life Systems, Inc. Polymeric coatings for controlled delivery of active agents
US6117147A (en) † 1998-09-30 2000-09-12 Sulzer Carbomedics Inc. Device and method for reinforcing an anastomotic site
NL1010386C2 (en) † 1998-10-23 2000-04-26 Eric Berreklouw Anastomosis device.
US6113612A (en) * 1998-11-06 2000-09-05 St. Jude Medical Cardiovascular Group, Inc. Medical anastomosis apparatus
US6059813A (en) 1998-11-06 2000-05-09 Scimed Life Systems, Inc. Rolling membrane stent delivery system
US6290906B1 (en) 1998-11-09 2001-09-18 Aga Gas, Inc. Method for removing sterilant from objects subjected to gaseous sterilization
US6187024B1 (en) * 1998-11-10 2001-02-13 Target Therapeutics, Inc. Bioactive coating for vaso-occlusive devices
US6190403B1 (en) 1998-11-13 2001-02-20 Cordis Corporation Low profile radiopaque stent with increased longitudinal flexibility and radial rigidity
FR2785812B1 (en) 1998-11-16 2002-11-29 Commissariat Energie Atomique BIOACTIVE PROSTHESES, IN PARTICULAR WITH IMMUNOSUPPRESSIVE PROPERTIES, ANTISTENOSIS AND ANTITHROMBOSIS, AND THEIR MANUFACTURE
US6336937B1 (en) * 1998-12-09 2002-01-08 Gore Enterprise Holdings, Inc. Multi-stage expandable stent-graft
US6120847A (en) 1999-01-08 2000-09-19 Scimed Life Systems, Inc. Surface treatment method for stent coating
US6309380B1 (en) 1999-01-27 2001-10-30 Marian L. Larson Drug delivery via conformal film
US6143354A (en) 1999-02-08 2000-11-07 Medtronic Inc. One-step method for attachment of biomolecules to substrate surfaces
US6440364B1 (en) 1999-02-16 2002-08-27 Ethicon, Inc. Method of degassing absorbable suture products
KR20010102130A (en) 1999-02-19 2001-11-15 리스 데브라 케이. Inhibitors for use in hemostasis and immune function
WO2000051662A1 (en) † 1999-03-04 2000-09-08 Tepha, Inc. Bioabsorbable, biocompatible polymers for tissue engineering
WO2000053126A1 (en) 1999-03-10 2000-09-14 Aesculap Ag & Co. Kg Implant for fixing an articulated joint
US6245012B1 (en) 1999-03-19 2001-06-12 Nmt Medical, Inc. Free standing filter
US6368658B1 (en) 1999-04-19 2002-04-09 Scimed Life Systems, Inc. Coating medical devices using air suspension
US6730349B2 (en) 1999-04-19 2004-05-04 Scimed Life Systems, Inc. Mechanical and acoustical suspension coating of medical implants
EP1054017B1 (en) 1999-05-10 2004-10-13 Abbott GmbH & Co. KG Salts of thrombin inhibitors
US6375676B1 (en) 1999-05-17 2002-04-23 Advanced Cardiovascular Systems, Inc. Self-expanding stent with enhanced delivery precision and stent delivery system
US6428550B1 (en) 1999-05-18 2002-08-06 Cardica, Inc. Sutureless closure and deployment system for connecting blood vessels
EP1180013B1 (en) 1999-05-27 2006-03-08 Biocompatibles UK Limited Local drug delivery
WO2000072764A1 (en) 1999-05-28 2000-12-07 The Board Of Trustees Of The Leland Stanford Junior University Anastomosis system and methods for use
US6315790B1 (en) 1999-06-07 2001-11-13 Scimed Life Systems, Inc. Radiopaque marker bands
US6258121B1 (en) 1999-07-02 2001-07-10 Scimed Life Systems, Inc. Stent coating
US6179187B1 (en) * 1999-07-07 2001-01-30 Mark L. Lemire Ergonomically enhanced backpack
US6165185A (en) 1999-07-28 2000-12-26 Vasconnect, Inc. Method for interconnecting vessels in a patient
US6309660B1 (en) 1999-07-28 2001-10-30 Edwards Lifesciences Corp. Universal biocompatible coating platform for medical devices
US6458140B2 (en) 1999-07-28 2002-10-01 Vasconnect, Inc. Devices and methods for interconnecting vessels
US6179861B1 (en) 1999-07-30 2001-01-30 Incept Llc Vascular device having one or more articulation regions and methods of use
US6287628B1 (en) 1999-09-03 2001-09-11 Advanced Cardiovascular Systems, Inc. Porous prosthesis and a method of depositing substances into the pores
US6713119B2 (en) 1999-09-03 2004-03-30 Advanced Cardiovascular Systems, Inc. Biocompatible coating for a prosthesis and a method of forming the same
US6663606B1 (en) 1999-10-28 2003-12-16 Scimed Life Systems, Inc. Biocompatible medical devices
US20010053931A1 (en) 1999-11-24 2001-12-20 Salvatore J. Abbruzzese Thin-layered, endovascular silk-covered stent device and method of manufacture thereof
EP1235521A2 (en) † 1999-12-06 2002-09-04 Converge Medical, Inc. End-side anastomosis systems
US6251136B1 (en) 1999-12-08 2001-06-26 Advanced Cardiovascular Systems, Inc. Method of layering a three-coated stent using pharmacological and polymeric agents
US6602287B1 (en) 1999-12-08 2003-08-05 Advanced Cardiovascular Systems, Inc. Stent with anti-thrombogenic coating
US20010007083A1 (en) 1999-12-29 2001-07-05 Roorda Wouter E. Device and active component for inhibiting formation of thrombus-inflammatory cell matrix
US6471979B2 (en) 1999-12-29 2002-10-29 Estrogen Vascular Technology, Llc Apparatus and method for delivering compounds to a living organism
WO2001049338A1 (en) 1999-12-30 2001-07-12 Li Wei Pin Controlled delivery of therapeutic agents by insertable medical devices
US6245100B1 (en) 2000-02-01 2001-06-12 Cordis Corporation Method for making a self-expanding stent-graft
EP1132058A1 (en) 2000-03-06 2001-09-12 Advanced Laser Applications Holding S.A. Intravascular prothesis
US6379382B1 (en) 2000-03-13 2002-04-30 Jun Yang Stent having cover with drug delivery capability
US6818247B1 (en) 2000-03-31 2004-11-16 Advanced Cardiovascular Systems, Inc. Ethylene vinyl alcohol-dimethyl acetamide composition and a method of coating a stent
US6517573B1 (en) 2000-04-11 2003-02-11 Endovascular Technologies, Inc. Hook for attaching to a corporeal lumen and method of manufacturing
US20050002986A1 (en) 2000-05-12 2005-01-06 Robert Falotico Drug/drug delivery systems for the prevention and treatment of vascular disease
US20040243097A1 (en) 2000-05-12 2004-12-02 Robert Falotico Antiproliferative drug and delivery device
US6776796B2 (en) 2000-05-12 2004-08-17 Cordis Corportation Antiinflammatory drug and delivery device
US7300662B2 (en) 2000-05-12 2007-11-27 Cordis Corporation Drug/drug delivery systems for the prevention and treatment of vascular disease
US7419678B2 (en) 2000-05-12 2008-09-02 Cordis Corporation Coated medical devices for the prevention and treatment of vascular disease
US8236048B2 (en) 2000-05-12 2012-08-07 Cordis Corporation Drug/drug delivery systems for the prevention and treatment of vascular disease
US6627246B2 (en) 2000-05-16 2003-09-30 Ortho-Mcneil Pharmaceutical, Inc. Process for coating stents and other medical devices using super-critical carbon dioxide
US6673385B1 (en) 2000-05-31 2004-01-06 Advanced Cardiovascular Systems, Inc. Methods for polymeric coatings stents
US6656966B2 (en) † 2000-06-22 2003-12-02 Nitromed, Inc. Nitrosated and nitrosylated taxanes, compositions and methods of use
US7077836B2 (en) 2000-07-21 2006-07-18 Vein Rx, Inc. Methods and apparatus for sclerosing the wall of a varicose vein
CA2419379C (en) 2000-08-15 2011-10-11 Surmodics, Inc. Medicament incorporation matrix
US6506210B1 (en) * 2000-09-01 2003-01-14 Angiolink Corporation Wound site management and wound closure device
US6254632B1 (en) 2000-09-28 2001-07-03 Advanced Cardiovascular Systems, Inc. Implantable medical device having protruding surface structures for drug delivery and cover attachment
JP5100951B2 (en) 2000-09-29 2012-12-19 コーディス・コーポレイション Coated medical device
US20020111590A1 (en) 2000-09-29 2002-08-15 Davila Luis A. Medical devices, drug coatings and methods for maintaining the drug coatings thereon
US20070276473A1 (en) 2000-09-29 2007-11-29 Llanos Gerard H Medical Devices, Drug Coatings and Methods for Maintaining the Drug Coatings Thereon
US20020051730A1 (en) 2000-09-29 2002-05-02 Stanko Bodnar Coated medical devices and sterilization thereof
US7261735B2 (en) 2001-05-07 2007-08-28 Cordis Corporation Local drug delivery devices and methods for maintaining the drug coatings thereon
US20060222756A1 (en) 2000-09-29 2006-10-05 Cordis Corporation Medical devices, drug coatings and methods of maintaining the drug coatings thereon
US6746773B2 (en) 2000-09-29 2004-06-08 Ethicon, Inc. Coatings for medical devices
US6764507B2 (en) 2000-10-16 2004-07-20 Conor Medsystems, Inc. Expandable medical device with improved spatial distribution
US6833153B1 (en) 2000-10-31 2004-12-21 Advanced Cardiovascular Systems, Inc. Hemocompatible coatings on hydrophobic porous polymers
US7087078B2 (en) 2000-11-21 2006-08-08 Schering Ag Tubular vascular implants (stents) and methods for producing the same
US6579319B2 (en) 2000-11-29 2003-06-17 Medicinelodge, Inc. Facet joint replacement
US6545097B2 (en) 2000-12-12 2003-04-08 Scimed Life Systems, Inc. Drug delivery compositions and medical devices containing block copolymer
US20020103526A1 (en) 2000-12-15 2002-08-01 Tom Steinke Protective coating for stent
US7018405B2 (en) 2000-12-22 2006-03-28 Avantec Vascular Corporation Intravascular delivery of methylprednisolone
US6939375B2 (en) 2000-12-22 2005-09-06 Avantac Vascular Corporation Apparatus and methods for controlled substance delivery from implanted prostheses
US6471980B2 (en) 2000-12-22 2002-10-29 Avantec Vascular Corporation Intravascular delivery of mycophenolic acid
ES2621652T3 (en) † 2001-01-16 2017-07-04 Vascular Therapies, Inc. Implantable device containing resorbable matrix material and rapamycin to prevent or treat vasculoproliferative diseases
US7179251B2 (en) 2001-01-17 2007-02-20 Boston Scientific Scimed, Inc. Therapeutic delivery balloon
WO2002065954A1 (en) 2001-02-16 2002-08-29 Queen's University At Kingston Method and device for treating scoliosis
WO2002066092A2 (en) 2001-02-23 2002-08-29 Angiogene Inc. Drug eluting device for treating vascular diseases
US7229441B2 (en) 2001-02-28 2007-06-12 Warsaw Orthopedic, Inc. Flexible systems for spinal stabilization and fixation
WO2002072167A1 (en) 2001-03-13 2002-09-19 Implant Sciences Corporation. Drug eluting encapsulated stent
US7048939B2 (en) 2001-04-20 2006-05-23 The Board Of Trustees Of The Leland Stanford Junior University Methods for the inhibition of neointima formation
US7056339B2 (en) 2001-04-20 2006-06-06 The Board Of Trustees Of The Leland Stanford Junior University Drug delivery platform
US20020173803A1 (en) 2001-05-01 2002-11-21 Stephen Ainsworth Self-closing surgical clip for tissue
US8182527B2 (en) 2001-05-07 2012-05-22 Cordis Corporation Heparin barrier coating for controlled drug release
US6787179B2 (en) 2001-06-29 2004-09-07 Ethicon, Inc. Sterilization of bioactive coatings
US6656216B1 (en) 2001-06-29 2003-12-02 Advanced Cardiovascular Systems, Inc. Composite stent with regioselective material
US6626920B2 (en) 2001-07-05 2003-09-30 Converge Medical, Inc. Distal anastomosis system
DE20112123U1 (en) 2001-07-23 2001-09-27 Aesculap Ag & Co Kg Facet joint implant
US7195640B2 (en) 2001-09-25 2007-03-27 Cordis Corporation Coated medical devices for the treatment of vulnerable plaque
US6753071B1 (en) 2001-09-27 2004-06-22 Advanced Cardiovascular Systems, Inc. Rate-reducing membrane for release of an agent
US20030065377A1 (en) 2001-09-28 2003-04-03 Davila Luis A. Coated medical devices
US6517889B1 (en) 2001-11-26 2003-02-11 Swaminathan Jayaraman Process for coating a surface of a stent
US7029482B1 (en) 2002-01-22 2006-04-18 Cardica, Inc. Integrated anastomosis system
US20030204168A1 (en) 2002-04-30 2003-10-30 Gjalt Bosma Coated vascular devices
US6919100B2 (en) 2003-01-22 2005-07-19 Cordis Corporation Method for coating medical devices
US6852122B2 (en) 2003-01-23 2005-02-08 Cordis Corporation Coated endovascular AAA device
US7186518B2 (en) 2003-11-21 2007-03-06 Dade Behring Inc. Method and composition useful for determining FK 506
JP4948574B2 (en) 2009-07-24 2012-06-06 株式会社デンソー Card edge connector and assembly method thereof

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