CA2421491A1 - Rotational thrombectomy device - Google Patents

Rotational thrombectomy device Download PDF

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Publication number
CA2421491A1
CA2421491A1 CA002421491A CA2421491A CA2421491A1 CA 2421491 A1 CA2421491 A1 CA 2421491A1 CA 002421491 A CA002421491 A CA 002421491A CA 2421491 A CA2421491 A CA 2421491A CA 2421491 A1 CA2421491 A1 CA 2421491A1
Authority
CA
Canada
Prior art keywords
wire
balloon
thrombectomy apparatus
thrombectomy
configuration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002421491A
Other languages
French (fr)
Other versions
CA2421491C (en
Inventor
James F. Mcguckin, Jr.
Peter W. J. Hinchliffe
Walter H. Peters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rex Medical LP
Original Assignee
Rex Medical LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rex Medical LP filed Critical Rex Medical LP
Publication of CA2421491A1 publication Critical patent/CA2421491A1/en
Application granted granted Critical
Publication of CA2421491C publication Critical patent/CA2421491C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/3205Excision instruments
    • A61B17/3207Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A61B17/320758Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with a rotating cutting instrument, e.g. motor driven
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22031Gripping instruments, e.g. forceps, for removing or smashing calculi
    • A61B17/22032Gripping instruments, e.g. forceps, for removing or smashing calculi having inflatable gripping elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0041Catheters; Hollow probes characterised by the form of the tubing pre-formed, e.g. specially adapted to fit with the anatomy of body channels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J1/00Details of electrodes, of magnetic control means, of screens, or of the mounting or spacing thereof, common to two or more basic types of discharge tubes or lamps
    • H01J1/02Main electrodes
    • H01J1/30Cold cathodes, e.g. field-emissive cathode
    • H01J1/304Field-emissive cathodes
    • H01J1/3042Field-emissive cathodes microengineered, e.g. Spindt-type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00681Aspects not otherwise provided for
    • A61B2017/00734Aspects not otherwise provided for battery operated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22082Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance
    • A61B2017/22084Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance stone- or thrombus-dissolving
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B2017/320004Surgical cutting instruments abrasive
    • A61B2017/320008Scrapers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/3205Excision instruments
    • A61B17/3207Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A61B2017/320733Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with a flexible cutting or scraping element, e.g. with a whip-like distal filament member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/06Body-piercing guide needles or the like
    • A61M25/0662Guide tubes
    • A61M2025/0681Systems with catheter and outer tubing, e.g. sheath, sleeve or guide tube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026Multi-lumen catheters with stationary elements
    • A61M25/0032Multi-lumen catheters with stationary elements characterized by at least one unconventionally shaped lumen, e.g. polygons, ellipsoids, wedges or shapes comprising concave and convex parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/1011Multiple balloon catheters
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J2201/00Electrodes common to discharge tubes
    • H01J2201/30Cold cathodes
    • H01J2201/319Circuit elements associated with the emitters by direct integration

Abstract

A thrombectomy apparatus for breaking up thrombus or other obstructive material in a lumen of a vascular graft or vessel comprising a flexible sheath, and a wire positioned within the flexible sheath wherein the wire and flexible sheath are relatively movable. The wire is substantially sinuous in configuration and assumes a substantially sinuous shape when in the deployed position and assumes a straighter position in the retracted position. The wire is operatively connected to a motor for rotation of the wire to enable peaks of the sinuous wire to contact a wall of the lumen to break up the thrombus or other obstructive material.

Claims (21)

1. A thrombectomy apparatus for breaking up thrombus or other obstructive material in a lumen of a vascular graft or vessel, the apparatus comprising a flexible sheath and a wire positioned within the flexible sheath, the wire and flexible sheath being relatively movable so the wire has a first configuration and a second deployed configuration, the wire being sinuous in configuration and assuming its sinuous configuration when in the deployed configuration and having a straighter configuration in the first configuration, the wire being operatively connected to a motor for rotation of the wire to enable peaks of the sinuous wire to contact a wall of the lumen to break up the thrombus or other obstructive material.
2. The thrombectomy apparatus of claim 1, wherein the wire is composed of an inner core and an outer coil.
3. The thrombectomy apparatus of claim 2, wherein the inner core is formed by at least two wires twisted together.
4. The thrombectomy apparatus of any one of claims 2 and 3, wherein in manufacture the inner core is slid within the outer layer and welded together at proximal and distal ends.
5. The thrombectomy apparatus of any one of claims 1 to 4, wherein the wire is composed of a plurality of wires twisted together.
6. The thrombectomy apparatus of any one of claims 1 to 5, further comprising a soft blunt tip affixed to a distal end of the wire.
7. The thrombectomy apparatus of any one of claims 1 to 6, wherein a distal portion of the flexible sheath is at an angle to a longitudinal axis of the sheath.
8. The thrombectomy apparatus of any one of claims 1 to 7, further comprising a housing, the wire extending from the housing, the housing further including a battery and a motor for causing rotation of the wire.
9. The thrombectomy apparatus of any one of claims 1 to 8, further comprising a metal tube operatively connected to the motor, the wire connected to the metal tube such that rotation of the metal tube rotates the wire.
10. The thrombectomy apparatus of any one of claims 1 to 9, further comprising first and second balloons, and the flexible sheath has first and second lumens, the first lumen communicating with the first balloon and the second lumen communicating with the second balloon.
11. The thrombectomy apparatus of claim 10, wherein the first balloon is an angioplasty balloon and the second balloon is configured for engaging and pulling an arterial plug, wherein the first balloon is proximal of the second balloon.
12. The thrombectomy apparatus of any one of claims 1 to 10, further comprising an angioplasty balloon expandable radially with respect to the flexible sheath.
13. The thrombectomy apparatus of any one of claims 1 to 9 and 12, further comprising an inflatable balloon for engaging and pulling an arterial plug into the lumen of the graft, the balloon expandable radially with respect to the flexible sheath.
14. A thrombectomy apparatus comprising a flexible sheath and a rotatable wire positioned within the flexible sheath, the wire and flexible sheath being relatively slidable so the wire is movable between a substantially straightened position and a deployed position where it assumes a curved configuration, in the curved configuration the wire having a first arcuate region extending in a first direction and a second arcuate region spaced longitudinally from the first arcuate region and extending in a second direction, the first and second arcuate regions configured to break up thrombotic material as the wire spins.
15. A thrombectomy apparatus of claim 14, wherein the wire is formed of an inner core of twisted wires and an outer coil.
16. The thrombectomy apparatus of any one of claims 14 and 15, further comprising an expandable balloon and wherein the sheath contains a first lumen to receive the wire and a second lumen communicating with the balloon for injection of fluid to inflate the balloon.
17. A thrombectomy apparatus comprising a flexible sheath and a wire rotatably positioned within the flexible sheath, the wire composed of at least one wire forming an inner core and at least one wire around the inner core to form an outer layer, the wire having a first arcuate region extending in a first direction, a second arcuate region extending in a second direction, and a substantially linear region, the first and second arcuate regions breaking up thrombotic material in a vascular structure as the wire spins.
18. A thrombectomy apparatus comprising a flexible tube, a wire having a non-linear configuration and positioned within the flexible tube and rotatable with respect to the flexible tube, the wire having a non-linear configuration, first and second balloons inflatable to expand radially with respect to the flexible tube, and a motor for rotating the wire to break up thrombotic material as the wire rotates about its axis.
19. A thrombectomy apparatus for performing a thrombectomy procedure to break up thrombus from a graft functioning as a shunt between an artery and a vein, the apparatus comprising a flexible catheter having a declotting mechanism to break up thrombotic material or other obstructive material, a first angioplasty balloon inflatable to expand radially with respect to the flexible catheter to perform an angioplasty procedure, and a second balloon inflatable to a configuration capable of pulling vascular material into the graft.
20. The use of a thrombectomy device for breaking up the thrombotic material from a lumen of a vascular graft or vessel.
21. The use of a thrombectomy device for performing a thrombectomy procedure to break up thrombotic material in a vascular graft which forms a shunt between an artery and a vein.
CA2421491A 2002-04-01 2003-03-11 Rotational thrombectomy device Expired - Fee Related CA2421491C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/113,248 2002-04-01
US10/113,248 US7037316B2 (en) 1997-07-24 2002-04-01 Rotational thrombectomy device

Publications (2)

Publication Number Publication Date
CA2421491A1 true CA2421491A1 (en) 2003-10-01
CA2421491C CA2421491C (en) 2011-05-31

Family

ID=28041024

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2421491A Expired - Fee Related CA2421491C (en) 2002-04-01 2003-03-11 Rotational thrombectomy device

Country Status (5)

Country Link
US (2) US7037316B2 (en)
EP (1) EP1350473B1 (en)
JP (1) JP4418164B2 (en)
CA (1) CA2421491C (en)
ES (1) ES2823561T3 (en)

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US20020173812A1 (en) 2002-11-21
US20060074441A1 (en) 2006-04-06
EP1350473A2 (en) 2003-10-08
CA2421491C (en) 2011-05-31
US7507246B2 (en) 2009-03-24
EP1350473A3 (en) 2004-10-06

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