CA2417315A1 - Stent with enhanced crossability - Google Patents
Stent with enhanced crossability Download PDFInfo
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- CA2417315A1 CA2417315A1 CA002417315A CA2417315A CA2417315A1 CA 2417315 A1 CA2417315 A1 CA 2417315A1 CA 002417315 A CA002417315 A CA 002417315A CA 2417315 A CA2417315 A CA 2417315A CA 2417315 A1 CA2417315 A1 CA 2417315A1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/9155—Adjacent bands being connected to each other
- A61F2002/91558—Adjacent bands being connected to each other connected peak to peak
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/9155—Adjacent bands being connected to each other
- A61F2002/91583—Adjacent bands being connected to each other by a bridge, whereby at least one of its ends is connected along the length of a strut between two consecutive apices within a band
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0028—Shapes in the form of latin or greek characters
- A61F2230/0054—V-shaped
Abstract
A stent design is disclosed which has a flexible connector which has flexible arcs and flexible struts aligned similarly to the radial arcs and radial struts, such that the alignment of the flexible connector within the stent decreases the likelihood of the stent's catching on a non-smooth surface.
Description
TENT WITH ENHANCED C~tOSSAEILITY
FIELD OF THE INVEt~J°TION
s The present invention generally relatE;s to implantable intraluminal medical devices, particularly stents. The present invention relates to an implantable intraluminal device which is useful for repairing or serving as a conduit for vessels narrowed or occluded by diisease or for use in other body passageways requiring reinforcement or the like. More specifically, the present invention discloses an alignment of a flexible connector within a stent which decreases the likelihood of the stent's catching on a non-smooth surface.
~ACICC~IaOIJND OF °TFiE IPJVENTION
As background to a discussion of stent:~, one notes that in the 1970s, the technique of percutaneous transluminal coronary angioplasty (PTCA) was developed for the treatment of atheroscl'erosis. Atherosclerosis is the build-up of fatty deposits or plaque on the inner walls of a patient's arteries;
ao these lesions decrease the effective size of the artery lumen and limit blood flow through the artery, prospectively causing a myocardial infarction or heart attack if the lesions occur in coronary arteries that supply oxygenated blood to the heart muscles. In the angioplasity procedure, a guide wire is inserted into the femoral artery and is passE;d through the aorta into the diseased coronary artery. A catheter having a~ balloon attached to its distal end is advanced along the guide wire to a point where the sclerotic lesions limit blood flow through the coronary artery. The balloon is then inflated, compressing the lesions radialfy outward against the wall of the artery and
FIELD OF THE INVEt~J°TION
s The present invention generally relatE;s to implantable intraluminal medical devices, particularly stents. The present invention relates to an implantable intraluminal device which is useful for repairing or serving as a conduit for vessels narrowed or occluded by diisease or for use in other body passageways requiring reinforcement or the like. More specifically, the present invention discloses an alignment of a flexible connector within a stent which decreases the likelihood of the stent's catching on a non-smooth surface.
~ACICC~IaOIJND OF °TFiE IPJVENTION
As background to a discussion of stent:~, one notes that in the 1970s, the technique of percutaneous transluminal coronary angioplasty (PTCA) was developed for the treatment of atheroscl'erosis. Atherosclerosis is the build-up of fatty deposits or plaque on the inner walls of a patient's arteries;
ao these lesions decrease the effective size of the artery lumen and limit blood flow through the artery, prospectively causing a myocardial infarction or heart attack if the lesions occur in coronary arteries that supply oxygenated blood to the heart muscles. In the angioplasity procedure, a guide wire is inserted into the femoral artery and is passE;d through the aorta into the diseased coronary artery. A catheter having a~ balloon attached to its distal end is advanced along the guide wire to a point where the sclerotic lesions limit blood flow through the coronary artery. The balloon is then inflated, compressing the lesions radialfy outward against the wall of the artery and
- 2 -substantially increasing the size of its internal lumen, to improve blood circulation through the artery.
Presently, it is the case that stents are increasingly being used in s place of or in addition to PTCA for treatmerst of atherosclerosis, with the intent of minimizing the need to repeatedly open an atherosclerotic artery.
Although a number of different designs for stents have been published, stents are generally configured as elongate cylindrical structures that are provided in a first state and can assume a second, different state, with the io second state having a substantially greater diameter than the first state.
A
stent is implanted in a patient using an appropriate delivery system for the type of stent being implaced within the patient's arterial system. There are two basic types of stents--those that are expanded radially outward due to the force from an inflated angioplasty type balloon, such as the Fix Velocity~
15 and Palmaz-Schatz~ stents, made by Cordis Corporation, and those that are self expanding, such as the SMAR~T'~ stent, made by Cordis Corporation.
Generally, stents, grafts, and graft stE:nts are implantable medical a o devices (sometimes termed implantable tubular prostheses) which are placed within blood vessels and other body passageways to treat disease conditions such as stenoses, occlusions, and aneurysms. That is, a stent is used as a tubular structure left inside the lumen of a duct to relieve an obstruction. Commonly, stents are inserted into the lumen in a non-a5 expanded form and are then expanded autonomously (or with the aid of a second device in situ. A typical method of expansion occurs through the use of a catheter mounted angioplasty balloon which is inflated within the stenosed vessel or body passageway in order to shear and disrupt the
Presently, it is the case that stents are increasingly being used in s place of or in addition to PTCA for treatmerst of atherosclerosis, with the intent of minimizing the need to repeatedly open an atherosclerotic artery.
Although a number of different designs for stents have been published, stents are generally configured as elongate cylindrical structures that are provided in a first state and can assume a second, different state, with the io second state having a substantially greater diameter than the first state.
A
stent is implanted in a patient using an appropriate delivery system for the type of stent being implaced within the patient's arterial system. There are two basic types of stents--those that are expanded radially outward due to the force from an inflated angioplasty type balloon, such as the Fix Velocity~
15 and Palmaz-Schatz~ stents, made by Cordis Corporation, and those that are self expanding, such as the SMAR~T'~ stent, made by Cordis Corporation.
Generally, stents, grafts, and graft stE:nts are implantable medical a o devices (sometimes termed implantable tubular prostheses) which are placed within blood vessels and other body passageways to treat disease conditions such as stenoses, occlusions, and aneurysms. That is, a stent is used as a tubular structure left inside the lumen of a duct to relieve an obstruction. Commonly, stents are inserted into the lumen in a non-a5 expanded form and are then expanded autonomously (or with the aid of a second device in situ. A typical method of expansion occurs through the use of a catheter mounted angioplasty balloon which is inflated within the stenosed vessel or body passageway in order to shear and disrupt the
- 3 -obstructions a associated with the wall components of the vessel and to obtain an enlarged lumen. Transluminal iimplantation of such devices requires that they be introduced to the site collapsed about or within an introduction device and released to self expand or are expanded by other s mechanisms to an expanded tubular state providing a lumen of approximately the same size as the patent ves:5el or duct lumen.
In the absence of a stent, restenosis may occur as a result of elastic recoil of the stenotic lesion. A number of scent: designs have been reported.
~o Such scents include those with rigid ends (8 mm) and a flexible median part of 7-21 mm. This device is formed of multiple parts and is not continuously flexible along the longitudinal axis. Other stent designs with rigid segments and flexible segments have also been described.
is Other stems are described as longitudinally flexible but consist of a plurality of cylindrical elements connected by flexible members. These designs have at least one disadvantage if, for example, protruding edges occur when the stent is flexed around a curve, raising the possibility of inadvertent retention of the stent on plaque deposited on arterial wails. This a o may cause the scent to cause some damage to the interior lining of healthy vessels.
Stents can be viewed as scaffoldings, of generally cylindrical symmetry, that function to physically support, and, if desired, expand the wall 2 s of the passageway. Typically, a stent consists of two or more struts or wire support members connected together into a lattice-like or open weave frame.
Most stents are compressible for insertion through small cavities, and are delivered to the desired implantation site perc;utaneously via a catheter or similar transluminal device. Once at the treatment site, the compressed stent is expanded to fit within or expand the lumen of the passageway. Stents are typically either self-expanding or are expanded by inflating a balloon that is positioned inside the compressed stent at the end of the catheter.
s Intravascular stents are often deployed after coronary angioplasty procedures to reduce complications, such as the collapse of arterial lining, associated with the procedure.
Stents have a lattice-like structure, which leaves spaces defined by the struts that form the stent. such spaces can allow plaque from the lesion to fall through the stent and enter the blood stream during stent deployment.
The spaces can also permit malignant tissue growth through the stent openings into the body passageway and can allow undesired contact between blood flowing through the blood vessel and damaged portions of i5 the vessel. Covered stents, in which a polymE:ric material surrounds and is attached to the stent, have been proposed to alleviate the problems associated with stent openings.
Di eased vessels are also treated witrr grafts. Grafts are generally z o tubular in morphology and are used to replace or create an anatomical passageway to provide a new conduit for fluidl, e.g. bloods Grafts are often made from a portion of a vein, but can also be~ constructed from a synthetic material to form a synthetic graft. Like stents, synthetic grafts can be positioned percutaneously via a catheter, for instance, to be placed at the zs site of an aneurysm to prevent further dilation and possible rupture of the diseased vessel. In certain instances, the draft material alone does not provide enough structural support for the graft., causing the graft to at least partially collapse and occlude or impede the flow of blood through the vessel. Grafts may be used with stents. For those cases wherein the graft material is synthetic, the combined structure is sometimes referred to as a synthetic stent-graft. Stents are also placed at the ends of synthetic grafts to help secure the ends of the synthetic graft to vessel walls.
The present invention pertains to a manner of arranging the flexible connectors of a stent to reduce the friction between the stent and the wall of the vessel during delivery.
The present invention also reduces the likelihood of protruding edges that occur when the stent is flexed around a curve which increase to a certain degree the possibility of retention of the stent on plaque deposited on arterial walls.
SUMMARY OF THE INVENTION
The present invention is generally directed to the arrangement of the flexible connectors of a stmt. The present invention further discloses that the arrangement of flexible connectors can cause the extremal dimensions of openings in the expanded stent to be reduced.
BRIEF DESCRIPTION ~F THE DRA1NINGS
Fig. 1 is a layout view of a prior art stent;
Fig. 2 is a layout view of a stent of the present invention;
Fig. 3 is a schematic view of an "N" shaped connection in both the expanded and unexpanded stents; and CR~-9$9 Fig. 4 is a schematic view of a "Z" shaped connection of the present invention in both the expanded and unexpandE:d stents.
DETAILED DESCRIPTION OF THE INVENTION
Briefly, Fig. 1 is a flat layout of a prior art stent, described by Fischell et al in IJ.S. Patent No. 6,190,403, having a uniform strut width for the to circumferential sets of strut members.
Fig. 2. is a flat layout of the scent of the iinvention, illustrating the radial strut 12 (along the longitudinal axis) and the flexible strut F (along the longitudinal axis). In this embodiment, adjacent rings of radial struts R~, R2 15 comprise periodic structures which are out-of-phase, meaning that peaks P~
in one ring R~ face peaks P2 in the adjacent ring R2 and that troughs T~ in one Ring R~ face troughs Tz in the adjacent ring R2. In the depicted embodiment, fiexible struts link adjacent peaks P of the periodic structure of radial struts R. (In a different embodiment, flexible struts can link non-ao adjacent peaks.) In other embodiments of the present invention, adjacent rings of radial struts comprise periodic structures which are in-phase, meaning that peaks in one ring face troughs in the adjacent ring, and flexible struts can link peak to trough or peak to peak.
z5 Fig. 3. is a schematic of a stent with an IV-connector in the unexpanded and expanded state.
_ 7 _ Fig. 4. is a schematic of a stent with a Z-connector in the unexpanded and expanded state, which shows a smaller circular area as the connector rotates into the cell.
s Angiopfasty, either coronary or general vascular, has advanced to become the most effective means for revascullarization of stenosed vessels.
Balloon catheter dependent angioplasty has consistently proven to be the most reliable and practical interventional procedure. ~ther ancillary technologies such as laser based treatment, or directional or rotational to arthrectomy, have proven to be either of limited effectiveness or dependent on balloon angioplasty for completi~n of the intended procedure. Restenosis following balloon-based angioplasty is the most serious drawback and is especially prevalent in the coronary artery system.
15 Many regimens have been designed to combat restenosis, with limited success, including laser based treatment and directional or rotational arthrectomy. Intravascular stenting, however, noticeably reduces the restenosis rate following angioplasty procedures. The procedure for intravascular stent placement typically involves pre-dilation of the target ao vessel using balloon angioplasty, followed by deployment of the stent, and expansion of the stent such that the dilated vessel walls are supported from the inside.
The intravascular stent functions as scaffolding for the lumen of a as vessel. The scaffolding of the vessel walls by the stent serve to: (a) prevent elastic recoil of the dilated vessel wall, (b) eliminate residual stenosis of the vessel; a common occurrence in balloon angioplasty procedures, (c) maintain the diameter of the stented vessel segment slightly larger than the native unobstructed vessel segments proximal and distal the stented segment and (d) as indicated by the latest clinical data, lower the restenosis rate. Following an angioplasty procedure, the restenosis rate of stented vessels has proven significantly lower than for unstented or otherwise treated vessels; treatments may include adjuvant drug therapy (including drug eluting stents) and other methods mentioned previously.
An example of an early conventional stent is the Palmaz-Schatz~
stent made by Cordis Corporation and at least partly described in Schatz, to U.S. Pat. 5,195,984 (the Schatz Patent). The stent described in the Schatz Patent consists of a series of elongated tubular members having a plurality of slots disposed substantially parallel to the longitudinal axis of the tubular members. The tubular members are connected by at least one flexible connector member.
Some current stent designs such as the CORDIS BX Velocity ~ stent, Cordis Corporation, Miami Lakes, FL, have thE; required flexibility and radial rigidity to provide an excellent clinical result. The present invention may be viewed as a modification over such stents.
Many current tubular stents use a multiplicity of circumferential sets of strut members connected by either straight longitudinal connecting links or undulating longitudinal connecting links. The circumferential sets of strut members are typically formed from a series of diagonal sections connected to curved sections forming a closed-ring, zig-zag structure. This structure opens up as the stent expands to form the element in the scent that provides structural support for the arterial wall. A single strut member can be thought of as a diagonal section connected to a curved section within one of the CR~-989 _ g _ circumferential sets of strut members. In current stent designs such as the BX Velocity ~ stent, these sets of strut members are formed from a single piece of metal having a uniform wall thickness and generally uniform strut width. Although a stent with uniform width of the strut members will function, s if the width is increased to add strength or radiopacity, the sets of strut members will experience increased strain upon expansion.
FIG. 1 shows a flat layout of an embodiment of a prior art stent described by Fischell et al in U.S. Patent No. 6,190,403. The stent 5 of FIG.
l0 1 is shown in its crimped, pre-deployed state as it would appear if it were cut longitudinally and then laid out into a flat, 2-dimensional configuration. The stent 5 comprises end sets of strut members 2 located at each end of the stent 5 and three central sets of strut members 6 connected each to the other by sets of longitudinally extending undulaiting °'N" links 4. The end sets 15 Of strut members 2 consist of alternating curved sections 7 and diagonal sections 9. The central sets of strut members 6 located longitudinally between the end sets of strut members 2 consist of alternating curved sections 3 and diagonal sections 8.
a o in the prior art stent 5, the longitudinally diagonal sections 9 of the end sets of strut members 2 are shorter in length than the longitudinally diagonal sections 8 of the central sets of strut members 6. The shorter diagonal sections 9 will reduce the stiff longitudinal length of metal at the ends of the stent 5 to improve deliverability (by reducing "fish-scaling") and a s will also increase the post-expansion strength of the end sets of strut members 2 as compared with the central sets. of strut members 6. In this prior art stent, the width of the curved sections 3 and 7 and the diagonal sections 8 and 9 are all the same. There is no variation in width within any set of strut members or between the end seta of strut members 2 and the central sets of strut members 6. The stent 5 is a design well suited to stainless steel having a wall thickness of 0.0(145'° or greater, such as found in the CORDIS BX Velocity~ stent.
Figure 3 is a schematic of a stent with a flexible N-connector in both the unexpended and the expanded state. The longitudinally extending undulating N sinks define a certain circular area between each pair of N
links, shown as a circle '°O" and illustrated in the "expanded" state in Figure 2.
Figure 4 is a schematic of a stent with a flexible Z-connector in both the unexpended and the expanded state. The longitudinally extending undulating Z links define a certain circular area illustrated in the "expanded"
state in Figure 3. One can see that there is <~ smaller circular area as the connector rotates into the cell. A Z link, or something with the symmetry of a "Z", will manifest greater expansion in the circumferential direction than an N-link. This greater extension will lower the distance of closest approach between links about the circumference. The nature of the extension of the Z
link, relative to the extension of the N-link, vvill decrease the distance of z o closest approach between consecutive Z links along the vertical axis, relative to the distance of closest approach of consecutive N links. The nature of the Z-link, or symmetry related link, relative to the N link, will create a smaller gap between links. The lowered dimension results in enhanced screening or filtering capability.
Thus, an embodiment of the present invention discloses an undulating longitudinal connecting link nominally in the shape of a "Z", as distinct from the prior art which disclose s an undulating longitudinal connecting link in the shape of an "N".
Embodiments of the longitudinal coronecting link of the present invention encompass undulating connecting links with the following properties. In a two dimensional representation as in Figure 1, define a Cartesian coordinate system wherein the '°x" axis (or horizontal axis) is the longitudinal axis of the figure and the '°y" .axis (or vertical axis) is the circumferential axis of the figure. An embodiment of the present invention encompasses undulating links wherein each individual fink comprises at least two points wherein the tangent is parallel to the y or circumferential axis. In terms analogized to calculus, one would say that each individual link comprises at least two points wherein the first derivative on this graph is infinite.
Embodiments of the longitudinal connecting links comprise an individual undulating link wherein the link has at least two points wherein the tangent is "vertical" and wherein each undulating connecting link posseses a midpoint, such that at the intersection of that midpoint with a circumference Z o of the stent (a vertical line in the two dimensional representation) there is inversion symmetry with respect to that intersection taken as the origin of a Cartesian coordinate system. For each point (x,y) of the undulating connecting member, there is a point (-x, -y).
In the absence of a stent, restenosis may occur as a result of elastic recoil of the stenotic lesion. A number of scent: designs have been reported.
~o Such scents include those with rigid ends (8 mm) and a flexible median part of 7-21 mm. This device is formed of multiple parts and is not continuously flexible along the longitudinal axis. Other stent designs with rigid segments and flexible segments have also been described.
is Other stems are described as longitudinally flexible but consist of a plurality of cylindrical elements connected by flexible members. These designs have at least one disadvantage if, for example, protruding edges occur when the stent is flexed around a curve, raising the possibility of inadvertent retention of the stent on plaque deposited on arterial wails. This a o may cause the scent to cause some damage to the interior lining of healthy vessels.
Stents can be viewed as scaffoldings, of generally cylindrical symmetry, that function to physically support, and, if desired, expand the wall 2 s of the passageway. Typically, a stent consists of two or more struts or wire support members connected together into a lattice-like or open weave frame.
Most stents are compressible for insertion through small cavities, and are delivered to the desired implantation site perc;utaneously via a catheter or similar transluminal device. Once at the treatment site, the compressed stent is expanded to fit within or expand the lumen of the passageway. Stents are typically either self-expanding or are expanded by inflating a balloon that is positioned inside the compressed stent at the end of the catheter.
s Intravascular stents are often deployed after coronary angioplasty procedures to reduce complications, such as the collapse of arterial lining, associated with the procedure.
Stents have a lattice-like structure, which leaves spaces defined by the struts that form the stent. such spaces can allow plaque from the lesion to fall through the stent and enter the blood stream during stent deployment.
The spaces can also permit malignant tissue growth through the stent openings into the body passageway and can allow undesired contact between blood flowing through the blood vessel and damaged portions of i5 the vessel. Covered stents, in which a polymE:ric material surrounds and is attached to the stent, have been proposed to alleviate the problems associated with stent openings.
Di eased vessels are also treated witrr grafts. Grafts are generally z o tubular in morphology and are used to replace or create an anatomical passageway to provide a new conduit for fluidl, e.g. bloods Grafts are often made from a portion of a vein, but can also be~ constructed from a synthetic material to form a synthetic graft. Like stents, synthetic grafts can be positioned percutaneously via a catheter, for instance, to be placed at the zs site of an aneurysm to prevent further dilation and possible rupture of the diseased vessel. In certain instances, the draft material alone does not provide enough structural support for the graft., causing the graft to at least partially collapse and occlude or impede the flow of blood through the vessel. Grafts may be used with stents. For those cases wherein the graft material is synthetic, the combined structure is sometimes referred to as a synthetic stent-graft. Stents are also placed at the ends of synthetic grafts to help secure the ends of the synthetic graft to vessel walls.
The present invention pertains to a manner of arranging the flexible connectors of a stent to reduce the friction between the stent and the wall of the vessel during delivery.
The present invention also reduces the likelihood of protruding edges that occur when the stent is flexed around a curve which increase to a certain degree the possibility of retention of the stent on plaque deposited on arterial walls.
SUMMARY OF THE INVENTION
The present invention is generally directed to the arrangement of the flexible connectors of a stmt. The present invention further discloses that the arrangement of flexible connectors can cause the extremal dimensions of openings in the expanded stent to be reduced.
BRIEF DESCRIPTION ~F THE DRA1NINGS
Fig. 1 is a layout view of a prior art stent;
Fig. 2 is a layout view of a stent of the present invention;
Fig. 3 is a schematic view of an "N" shaped connection in both the expanded and unexpanded stents; and CR~-9$9 Fig. 4 is a schematic view of a "Z" shaped connection of the present invention in both the expanded and unexpandE:d stents.
DETAILED DESCRIPTION OF THE INVENTION
Briefly, Fig. 1 is a flat layout of a prior art stent, described by Fischell et al in IJ.S. Patent No. 6,190,403, having a uniform strut width for the to circumferential sets of strut members.
Fig. 2. is a flat layout of the scent of the iinvention, illustrating the radial strut 12 (along the longitudinal axis) and the flexible strut F (along the longitudinal axis). In this embodiment, adjacent rings of radial struts R~, R2 15 comprise periodic structures which are out-of-phase, meaning that peaks P~
in one ring R~ face peaks P2 in the adjacent ring R2 and that troughs T~ in one Ring R~ face troughs Tz in the adjacent ring R2. In the depicted embodiment, fiexible struts link adjacent peaks P of the periodic structure of radial struts R. (In a different embodiment, flexible struts can link non-ao adjacent peaks.) In other embodiments of the present invention, adjacent rings of radial struts comprise periodic structures which are in-phase, meaning that peaks in one ring face troughs in the adjacent ring, and flexible struts can link peak to trough or peak to peak.
z5 Fig. 3. is a schematic of a stent with an IV-connector in the unexpanded and expanded state.
_ 7 _ Fig. 4. is a schematic of a stent with a Z-connector in the unexpanded and expanded state, which shows a smaller circular area as the connector rotates into the cell.
s Angiopfasty, either coronary or general vascular, has advanced to become the most effective means for revascullarization of stenosed vessels.
Balloon catheter dependent angioplasty has consistently proven to be the most reliable and practical interventional procedure. ~ther ancillary technologies such as laser based treatment, or directional or rotational to arthrectomy, have proven to be either of limited effectiveness or dependent on balloon angioplasty for completi~n of the intended procedure. Restenosis following balloon-based angioplasty is the most serious drawback and is especially prevalent in the coronary artery system.
15 Many regimens have been designed to combat restenosis, with limited success, including laser based treatment and directional or rotational arthrectomy. Intravascular stenting, however, noticeably reduces the restenosis rate following angioplasty procedures. The procedure for intravascular stent placement typically involves pre-dilation of the target ao vessel using balloon angioplasty, followed by deployment of the stent, and expansion of the stent such that the dilated vessel walls are supported from the inside.
The intravascular stent functions as scaffolding for the lumen of a as vessel. The scaffolding of the vessel walls by the stent serve to: (a) prevent elastic recoil of the dilated vessel wall, (b) eliminate residual stenosis of the vessel; a common occurrence in balloon angioplasty procedures, (c) maintain the diameter of the stented vessel segment slightly larger than the native unobstructed vessel segments proximal and distal the stented segment and (d) as indicated by the latest clinical data, lower the restenosis rate. Following an angioplasty procedure, the restenosis rate of stented vessels has proven significantly lower than for unstented or otherwise treated vessels; treatments may include adjuvant drug therapy (including drug eluting stents) and other methods mentioned previously.
An example of an early conventional stent is the Palmaz-Schatz~
stent made by Cordis Corporation and at least partly described in Schatz, to U.S. Pat. 5,195,984 (the Schatz Patent). The stent described in the Schatz Patent consists of a series of elongated tubular members having a plurality of slots disposed substantially parallel to the longitudinal axis of the tubular members. The tubular members are connected by at least one flexible connector member.
Some current stent designs such as the CORDIS BX Velocity ~ stent, Cordis Corporation, Miami Lakes, FL, have thE; required flexibility and radial rigidity to provide an excellent clinical result. The present invention may be viewed as a modification over such stents.
Many current tubular stents use a multiplicity of circumferential sets of strut members connected by either straight longitudinal connecting links or undulating longitudinal connecting links. The circumferential sets of strut members are typically formed from a series of diagonal sections connected to curved sections forming a closed-ring, zig-zag structure. This structure opens up as the stent expands to form the element in the scent that provides structural support for the arterial wall. A single strut member can be thought of as a diagonal section connected to a curved section within one of the CR~-989 _ g _ circumferential sets of strut members. In current stent designs such as the BX Velocity ~ stent, these sets of strut members are formed from a single piece of metal having a uniform wall thickness and generally uniform strut width. Although a stent with uniform width of the strut members will function, s if the width is increased to add strength or radiopacity, the sets of strut members will experience increased strain upon expansion.
FIG. 1 shows a flat layout of an embodiment of a prior art stent described by Fischell et al in U.S. Patent No. 6,190,403. The stent 5 of FIG.
l0 1 is shown in its crimped, pre-deployed state as it would appear if it were cut longitudinally and then laid out into a flat, 2-dimensional configuration. The stent 5 comprises end sets of strut members 2 located at each end of the stent 5 and three central sets of strut members 6 connected each to the other by sets of longitudinally extending undulaiting °'N" links 4. The end sets 15 Of strut members 2 consist of alternating curved sections 7 and diagonal sections 9. The central sets of strut members 6 located longitudinally between the end sets of strut members 2 consist of alternating curved sections 3 and diagonal sections 8.
a o in the prior art stent 5, the longitudinally diagonal sections 9 of the end sets of strut members 2 are shorter in length than the longitudinally diagonal sections 8 of the central sets of strut members 6. The shorter diagonal sections 9 will reduce the stiff longitudinal length of metal at the ends of the stent 5 to improve deliverability (by reducing "fish-scaling") and a s will also increase the post-expansion strength of the end sets of strut members 2 as compared with the central sets. of strut members 6. In this prior art stent, the width of the curved sections 3 and 7 and the diagonal sections 8 and 9 are all the same. There is no variation in width within any set of strut members or between the end seta of strut members 2 and the central sets of strut members 6. The stent 5 is a design well suited to stainless steel having a wall thickness of 0.0(145'° or greater, such as found in the CORDIS BX Velocity~ stent.
Figure 3 is a schematic of a stent with a flexible N-connector in both the unexpended and the expanded state. The longitudinally extending undulating N sinks define a certain circular area between each pair of N
links, shown as a circle '°O" and illustrated in the "expanded" state in Figure 2.
Figure 4 is a schematic of a stent with a flexible Z-connector in both the unexpended and the expanded state. The longitudinally extending undulating Z links define a certain circular area illustrated in the "expanded"
state in Figure 3. One can see that there is <~ smaller circular area as the connector rotates into the cell. A Z link, or something with the symmetry of a "Z", will manifest greater expansion in the circumferential direction than an N-link. This greater extension will lower the distance of closest approach between links about the circumference. The nature of the extension of the Z
link, relative to the extension of the N-link, vvill decrease the distance of z o closest approach between consecutive Z links along the vertical axis, relative to the distance of closest approach of consecutive N links. The nature of the Z-link, or symmetry related link, relative to the N link, will create a smaller gap between links. The lowered dimension results in enhanced screening or filtering capability.
Thus, an embodiment of the present invention discloses an undulating longitudinal connecting link nominally in the shape of a "Z", as distinct from the prior art which disclose s an undulating longitudinal connecting link in the shape of an "N".
Embodiments of the longitudinal coronecting link of the present invention encompass undulating connecting links with the following properties. In a two dimensional representation as in Figure 1, define a Cartesian coordinate system wherein the '°x" axis (or horizontal axis) is the longitudinal axis of the figure and the '°y" .axis (or vertical axis) is the circumferential axis of the figure. An embodiment of the present invention encompasses undulating links wherein each individual fink comprises at least two points wherein the tangent is parallel to the y or circumferential axis. In terms analogized to calculus, one would say that each individual link comprises at least two points wherein the first derivative on this graph is infinite.
Embodiments of the longitudinal connecting links comprise an individual undulating link wherein the link has at least two points wherein the tangent is "vertical" and wherein each undulating connecting link posseses a midpoint, such that at the intersection of that midpoint with a circumference Z o of the stent (a vertical line in the two dimensional representation) there is inversion symmetry with respect to that intersection taken as the origin of a Cartesian coordinate system. For each point (x,y) of the undulating connecting member, there is a point (-x, -y).
Claims (10)
1. A stent in the form of a thin-walled, multi-cellular, tubular structure having a longitudinal axis, the stent comprising:
a multiplicity of sets of strut members, each set of strut members being longitudinally separated each from the other and each set of strut members forming a closed, ring-like cylindrical section of the stent, each set of strut members consisting of a multiplicity of strut elements, each strut element consisting of one curved end strut that is joined at a junction point to one diagonal strut;
a multiplicity of sets of flexible links with each set of flexible links connecting two of the multiplicity of sets of strut members, each set of flexible links consisting of a multiplicity of individual flexible links, each individual flexible link being a single undulating structure that extends generally in the longitudinal direction that is parallel to the stent's longitudinal axis the shape of at least some of the individual flexible links being in the shape of a letter "Z" z-links, wherein each of said links has at least two generally curved segments, wherein the endpoints of each curved element of the z links lie generally in a circumferential direction.
a multiplicity of sets of strut members, each set of strut members being longitudinally separated each from the other and each set of strut members forming a closed, ring-like cylindrical section of the stent, each set of strut members consisting of a multiplicity of strut elements, each strut element consisting of one curved end strut that is joined at a junction point to one diagonal strut;
a multiplicity of sets of flexible links with each set of flexible links connecting two of the multiplicity of sets of strut members, each set of flexible links consisting of a multiplicity of individual flexible links, each individual flexible link being a single undulating structure that extends generally in the longitudinal direction that is parallel to the stent's longitudinal axis the shape of at least some of the individual flexible links being in the shape of a letter "Z" z-links, wherein each of said links has at least two generally curved segments, wherein the endpoints of each curved element of the z links lie generally in a circumferential direction.
2. The stent of claim 1 wherein each individual flexible link has two ends, each one of the two ends being fixedly attached to the multiplicity of strut elements thereon.
3. The stent of claim 1 wherein there are adjacent sets of strut members which are in-phase with one another.
4. The stent of claim 1 wherein there are adjacent sets of strut members which are out-of-phase with one another.
5. A stent of approximately cylindrical shape comprising a longitudinal axis and a radial axis, wherein the cross-section perpendicular to the longitudinal axis defines a circumference, the stent comprising:
a plurality of sets of circumferential members, each set of members being longitudinally separated each from the other and each set of members forming a closed, ring-like cylindrical section of the stent, each set of members consisting of a multiplicity of elements, each element consisting of one curved end;
a plurality of sets of flexible links with each set of flexible links connecting two of the elements, each set of flexible links consisting of a multiplicity of individual flexible links, each individual flexible link being a single undulating structure that extends generally along a circumference each individual flexible link has two ends, each one of the two ends being fixedly attached to the multiplicity of strut elements at an attachment pint thereon; and the shape of at least some of the individual flexible links being circumferentially expansible;
wherein each of said links has at least 4 curved segments.
a plurality of sets of circumferential members, each set of members being longitudinally separated each from the other and each set of members forming a closed, ring-like cylindrical section of the stent, each set of members consisting of a multiplicity of elements, each element consisting of one curved end;
a plurality of sets of flexible links with each set of flexible links connecting two of the elements, each set of flexible links consisting of a multiplicity of individual flexible links, each individual flexible link being a single undulating structure that extends generally along a circumference each individual flexible link has two ends, each one of the two ends being fixedly attached to the multiplicity of strut elements at an attachment pint thereon; and the shape of at least some of the individual flexible links being circumferentially expansible;
wherein each of said links has at least 4 curved segments.
6. A stent of approximately cylindrical shape comprising a longitudinal axis and a radial axis, wherein the cross-section approximately perpendicular to the longitudinal axis defines a circumference, the stent comprising:
a plurality of sets of circumferential members, wherein each set of members forming a closed, ring-like configuration about the circumference and each set of members is longitudinally separated each from the other, wherein each set of members consists of a multiplicity of elements, each element consisting of one curved end;
a plurality of flexible links, each individual flexible link being a single undulating structure that extends generally along a circumference and each individual flexible link has two ends, each one of the two ends being fixedly attached to the multiplicity of strut elements at an attachment point thereon;
and wherein at least some of the individual flexible links when viewed in elevation are formed in the shape of the letter "Z".
a plurality of sets of circumferential members, wherein each set of members forming a closed, ring-like configuration about the circumference and each set of members is longitudinally separated each from the other, wherein each set of members consists of a multiplicity of elements, each element consisting of one curved end;
a plurality of flexible links, each individual flexible link being a single undulating structure that extends generally along a circumference and each individual flexible link has two ends, each one of the two ends being fixedly attached to the multiplicity of strut elements at an attachment point thereon;
and wherein at least some of the individual flexible links when viewed in elevation are formed in the shape of the letter "Z".
7. A stent in the form of a thin-walled, multi-cellular, tubular structure having a longitudinal axis, the stent comprising a multiplicity of circumferential sets of strut members, each set of strut members being longitudinally separated each from the other, each set of strut members being connected to adjacent sets of strut members by longitudinal connecting links, each individual connecting link being a single undulating structure with at lest a portion of said connecting links generally extending along a circumference, wherein each single undulating structure is in the shape of a letter "Z";
wherein each of said links has at least two generally curved segments placed generally opposite each other in the longitudinal direction.
wherein each of said links has at least two generally curved segments placed generally opposite each other in the longitudinal direction.
8. The stent of claim 7 wherein upon expansion the centers of curvature of the two curved elements undulates around each other so that a link extends parallel to the circumference of the stent.
9. A stent of approximately cylindrical shape comprising a longitudinal axis and a radial axis, wherein the cross-section approximately perpendicular to the longitudinal axis defines a circumference, wherein there is an unexpanded state and an expanded state, the stent comprising:
a plurality of sets of circumferential members, wherein each set of members forms a closed, ring-like configuration about the circumference and each set of members is longitudinally separated each from the other, wherein each set of members consists of a multiplicity of elements, each element consisting of one curved end;
a plurality of flexible links, each flexible link being a single undulating structure and each individual flexible link having two ends, each individual flexible link has two ends, each one of the two ends being fixedly attached to the multiplicity of strut elements at an attachment pint thereon;
wherein pairs of circumferential members and flexible links define openings, which openings possess an area; and wherein the circumferential distance of the first and second portion of the flexible links increases on expansion.
a plurality of sets of circumferential members, wherein each set of members forms a closed, ring-like configuration about the circumference and each set of members is longitudinally separated each from the other, wherein each set of members consists of a multiplicity of elements, each element consisting of one curved end;
a plurality of flexible links, each flexible link being a single undulating structure and each individual flexible link having two ends, each individual flexible link has two ends, each one of the two ends being fixedly attached to the multiplicity of strut elements at an attachment pint thereon;
wherein pairs of circumferential members and flexible links define openings, which openings possess an area; and wherein the circumferential distance of the first and second portion of the flexible links increases on expansion.
10. A stent of approximately cylindrical shape comprising a longitudinal axis and a radial axis, wherein the cross-section approximately perpendicular to the longitudinal axis defines a circumference, wherein there is a normal state and an expanded state, the stent comprising:
a plurality of sets of circumferential members, wherein each set of members forms a closed, ring-like configuration about the circumference and each set of members is longitudinally separated each from the other, wherein each set of members consists of a multiplicity of elements, each element consisting of one curved end;
a plurality of flexible links, each flexible link being a single undulation and each individual flexible link having two ends, wherein pairs of circumferential members and flexible links define openings which openings possess an area;
wherein in the expanded state, a flexible fink expands into the opening defined by that flexible link and circumferential member pair.
a plurality of sets of circumferential members, wherein each set of members forms a closed, ring-like configuration about the circumference and each set of members is longitudinally separated each from the other, wherein each set of members consists of a multiplicity of elements, each element consisting of one curved end;
a plurality of flexible links, each flexible link being a single undulation and each individual flexible link having two ends, wherein pairs of circumferential members and flexible links define openings which openings possess an area;
wherein in the expanded state, a flexible fink expands into the opening defined by that flexible link and circumferential member pair.
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Families Citing this family (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6682554B2 (en) * | 1998-09-05 | 2004-01-27 | Jomed Gmbh | Methods and apparatus for a stent having an expandable web structure |
US7815763B2 (en) * | 2001-09-28 | 2010-10-19 | Abbott Laboratories Vascular Enterprises Limited | Porous membranes for medical implants and methods of manufacture |
US20020019660A1 (en) * | 1998-09-05 | 2002-02-14 | Marc Gianotti | Methods and apparatus for a curved stent |
US7887578B2 (en) | 1998-09-05 | 2011-02-15 | Abbott Laboratories Vascular Enterprises Limited | Stent having an expandable web structure |
US6755856B2 (en) * | 1998-09-05 | 2004-06-29 | Abbott Laboratories Vascular Enterprises Limited | Methods and apparatus for stenting comprising enhanced embolic protection, coupled with improved protection against restenosis and thrombus formation |
US7141062B1 (en) * | 2000-03-01 | 2006-11-28 | Medinol, Ltd. | Longitudinally flexible stent |
US8202312B2 (en) * | 2000-03-01 | 2012-06-19 | Medinol Ltd. | Longitudinally flexible stent |
US7758627B2 (en) * | 2000-03-01 | 2010-07-20 | Medinol, Ltd. | Longitudinally flexible stent |
US8920487B1 (en) | 2000-03-01 | 2014-12-30 | Medinol Ltd. | Longitudinally flexible stent |
US8496699B2 (en) * | 2000-03-01 | 2013-07-30 | Medinol Ltd. | Longitudinally flexible stent |
US8038708B2 (en) | 2001-02-05 | 2011-10-18 | Cook Medical Technologies Llc | Implantable device with remodelable material and covering material |
DE50112209D1 (en) * | 2001-09-18 | 2007-04-26 | Abbott Lab Vascular Entpr Ltd | stent |
US7137993B2 (en) | 2001-12-03 | 2006-11-21 | Xtent, Inc. | Apparatus and methods for delivery of multiple distributed stents |
US7147656B2 (en) | 2001-12-03 | 2006-12-12 | Xtent, Inc. | Apparatus and methods for delivery of braided prostheses |
US7892273B2 (en) | 2001-12-03 | 2011-02-22 | Xtent, Inc. | Custom length stent apparatus |
US20040186551A1 (en) * | 2003-01-17 | 2004-09-23 | Xtent, Inc. | Multiple independent nested stent structures and methods for their preparation and deployment |
US20040054398A1 (en) * | 2002-09-13 | 2004-03-18 | Cully Edward H. | Stent device with multiple helix construction |
US20040093056A1 (en) | 2002-10-26 | 2004-05-13 | Johnson Lianw M. | Medical appliance delivery apparatus and method of use |
US7959671B2 (en) | 2002-11-05 | 2011-06-14 | Merit Medical Systems, Inc. | Differential covering and coating methods |
US7875068B2 (en) | 2002-11-05 | 2011-01-25 | Merit Medical Systems, Inc. | Removable biliary stent |
US7637942B2 (en) | 2002-11-05 | 2009-12-29 | Merit Medical Systems, Inc. | Coated stent with geometry determinated functionality and method of making the same |
US20070239251A1 (en) * | 2002-12-31 | 2007-10-11 | Abbott Cardiovascular Systems Inc. | Flexible stent |
US7637934B2 (en) | 2003-03-31 | 2009-12-29 | Merit Medical Systems, Inc. | Medical appliance optical delivery and deployment apparatus and method |
US7604660B2 (en) | 2003-05-01 | 2009-10-20 | Merit Medical Systems, Inc. | Bifurcated medical appliance delivery apparatus and method |
US8333798B2 (en) | 2003-11-07 | 2012-12-18 | Merlin Md Pte Ltd. | Implantable medical devices with enhanced visibility, mechanical properties and biocompatability |
US7326236B2 (en) | 2003-12-23 | 2008-02-05 | Xtent, Inc. | Devices and methods for controlling and indicating the length of an interventional element |
US7323006B2 (en) | 2004-03-30 | 2008-01-29 | Xtent, Inc. | Rapid exchange interventional devices and methods |
US8715340B2 (en) * | 2004-03-31 | 2014-05-06 | Merlin Md Pte Ltd. | Endovascular device with membrane |
EP1734897A4 (en) * | 2004-03-31 | 2010-12-22 | Merlin Md Pte Ltd | A method for treating aneurysms |
US8500751B2 (en) | 2004-03-31 | 2013-08-06 | Merlin Md Pte Ltd | Medical device |
US20050288766A1 (en) * | 2004-06-28 | 2005-12-29 | Xtent, Inc. | Devices and methods for controlling expandable prostheses during deployment |
US8317859B2 (en) | 2004-06-28 | 2012-11-27 | J.W. Medical Systems Ltd. | Devices and methods for controlling expandable prostheses during deployment |
WO2006024489A2 (en) | 2004-08-30 | 2006-03-09 | Interstitial Therapeutics | Methods and compositions for the treatment of cell proliferation |
US8961583B2 (en) * | 2004-09-08 | 2015-02-24 | Cordis Corporation | Optimized flex link for expandable stent |
EP1809202A4 (en) * | 2004-12-22 | 2011-04-27 | Merlin Md Pte Ltd | A medical device |
ATE534345T1 (en) * | 2006-02-13 | 2011-12-15 | Merlin Md Pte Ltd | ENDOVASCULAR DEVICE WITH MEMBRANE |
CA2646885A1 (en) | 2006-03-20 | 2007-09-27 | Xtent, Inc. | Apparatus and methods for deployment of linked prosthetic segments |
WO2007140320A2 (en) | 2006-05-26 | 2007-12-06 | Nanyang Technological University | Implantable article, method of forming same and method for reducing thrombogenicity |
US20080077231A1 (en) * | 2006-07-06 | 2008-03-27 | Prescient Medical, Inc. | Expandable vascular endoluminal prostheses |
US20080085293A1 (en) * | 2006-08-22 | 2008-04-10 | Jenchen Yang | Drug eluting stent and therapeutic methods using c-Jun N-terminal kinase inhibitor |
US8814930B2 (en) * | 2007-01-19 | 2014-08-26 | Elixir Medical Corporation | Biodegradable endoprosthesis and methods for their fabrication |
US20080177373A1 (en) * | 2007-01-19 | 2008-07-24 | Elixir Medical Corporation | Endoprosthesis structures having supporting features |
US20130150943A1 (en) | 2007-01-19 | 2013-06-13 | Elixir Medical Corporation | Biodegradable endoprostheses and methods for their fabrication |
US20080199510A1 (en) | 2007-02-20 | 2008-08-21 | Xtent, Inc. | Thermo-mechanically controlled implants and methods of use |
US8974514B2 (en) * | 2007-03-13 | 2015-03-10 | Abbott Cardiovascular Systems Inc. | Intravascular stent with integrated link and ring strut |
US8486132B2 (en) * | 2007-03-22 | 2013-07-16 | J.W. Medical Systems Ltd. | Devices and methods for controlling expandable prostheses during deployment |
US8128626B2 (en) * | 2007-04-24 | 2012-03-06 | Flexfix, Llc | System and method for delivery conformation and removal of intramedullary bone fixation devices |
US8128679B2 (en) | 2007-05-23 | 2012-03-06 | Abbott Laboratories Vascular Enterprises Limited | Flexible stent with torque-absorbing connectors |
US8016874B2 (en) * | 2007-05-23 | 2011-09-13 | Abbott Laboratories Vascular Enterprises Limited | Flexible stent with elevated scaffolding properties |
US9144508B2 (en) | 2007-07-19 | 2015-09-29 | Back Bay Medical Inc. | Radially expandable stent |
US8337544B2 (en) * | 2007-12-20 | 2012-12-25 | Abbott Laboratories Vascular Enterprises Limited | Endoprosthesis having flexible connectors |
US7850726B2 (en) * | 2007-12-20 | 2010-12-14 | Abbott Laboratories Vascular Enterprises Limited | Endoprosthesis having struts linked by foot extensions |
US8920488B2 (en) * | 2007-12-20 | 2014-12-30 | Abbott Laboratories Vascular Enterprises Limited | Endoprosthesis having a stable architecture |
US9101503B2 (en) | 2008-03-06 | 2015-08-11 | J.W. Medical Systems Ltd. | Apparatus having variable strut length and methods of use |
US10898620B2 (en) | 2008-06-20 | 2021-01-26 | Razmodics Llc | Composite stent having multi-axial flexibility and method of manufacture thereof |
US8206636B2 (en) | 2008-06-20 | 2012-06-26 | Amaranth Medical Pte. | Stent fabrication via tubular casting processes |
US8206635B2 (en) | 2008-06-20 | 2012-06-26 | Amaranth Medical Pte. | Stent fabrication via tubular casting processes |
US8262692B2 (en) * | 2008-09-05 | 2012-09-11 | Merlin Md Pte Ltd | Endovascular device |
JP4852631B2 (en) * | 2009-06-28 | 2012-01-11 | 株式会社沖データ | Communication device and connection control method thereof |
US9199066B2 (en) | 2010-03-12 | 2015-12-01 | Quattro Vascular Pte Ltd. | Device and method for compartmental vessel treatment |
EP2811947B1 (en) | 2012-02-08 | 2019-03-27 | TriReme Medical, LLC | Constraining structure with non-linear axial struts |
US9216033B2 (en) * | 2012-02-08 | 2015-12-22 | Quattro Vascular Pte Ltd. | System and method for treating biological vessels |
US10940167B2 (en) | 2012-02-10 | 2021-03-09 | Cvdevices, Llc | Methods and uses of biological tissues for various stent and other medical applications |
EP2833837B1 (en) | 2012-04-06 | 2023-03-29 | Merlin MD PTE Ltd. | Devices for treating an aneurysm |
AU2014214700B2 (en) | 2013-02-11 | 2018-01-18 | Cook Medical Technologies Llc | Expandable support frame and medical device |
US9730819B2 (en) | 2014-08-15 | 2017-08-15 | Elixir Medical Corporation | Biodegradable endoprostheses and methods of their fabrication |
US9259339B1 (en) | 2014-08-15 | 2016-02-16 | Elixir Medical Corporation | Biodegradable endoprostheses and methods of their fabrication |
US9855156B2 (en) * | 2014-08-15 | 2018-01-02 | Elixir Medical Corporation | Biodegradable endoprostheses and methods of their fabrication |
US9480588B2 (en) | 2014-08-15 | 2016-11-01 | Elixir Medical Corporation | Biodegradable endoprostheses and methods of their fabrication |
US9381103B2 (en) * | 2014-10-06 | 2016-07-05 | Abbott Cardiovascular Systems Inc. | Stent with elongating struts |
JP6803838B2 (en) | 2014-11-17 | 2020-12-23 | トライレム・メディカル・エルエルシー | Balloon catheter system and how to use this system |
CN110742709B (en) * | 2016-03-18 | 2022-06-28 | 复旦大学附属中山医院 | Aorta bare stent and aorta interlayer stent |
US10758381B2 (en) | 2016-03-31 | 2020-09-01 | Vesper Medical, Inc. | Intravascular implants |
US11622872B2 (en) | 2016-05-16 | 2023-04-11 | Elixir Medical Corporation | Uncaging stent |
CN113143536B (en) | 2016-05-16 | 2022-08-30 | 万能医药公司 | Opening support |
US10849769B2 (en) | 2017-08-23 | 2020-12-01 | Vesper Medical, Inc. | Non-foreshortening stent |
US11357650B2 (en) | 2019-02-28 | 2022-06-14 | Vesper Medical, Inc. | Hybrid stent |
US11628076B2 (en) | 2017-09-08 | 2023-04-18 | Vesper Medical, Inc. | Hybrid stent |
US10271977B2 (en) | 2017-09-08 | 2019-04-30 | Vesper Medical, Inc. | Hybrid stent |
US10835398B2 (en) | 2017-11-03 | 2020-11-17 | Covidien Lp | Meshes and devices for treating vascular defects |
US11364134B2 (en) | 2018-02-15 | 2022-06-21 | Vesper Medical, Inc. | Tapering stent |
US10500078B2 (en) | 2018-03-09 | 2019-12-10 | Vesper Medical, Inc. | Implantable stent |
CN113069256B (en) * | 2021-03-26 | 2022-12-09 | 珠海通桥医疗科技有限公司 | Intracranial flexible closed loop stent |
Family Cites Families (106)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3657744A (en) * | 1970-05-08 | 1972-04-25 | Univ Minnesota | Method for fixing prosthetic implants in a living body |
US4388735A (en) * | 1980-11-03 | 1983-06-21 | Shiley Inc. | Low profile prosthetic xenograft heart valve |
CA1204643A (en) * | 1981-09-16 | 1986-05-20 | Hans I. Wallsten | Device for application in blood vessels or other difficulty accessible locations and its use |
US4512338A (en) * | 1983-01-25 | 1985-04-23 | Balko Alexander B | Process for restoring patency to body vessels |
US4503569A (en) * | 1983-03-03 | 1985-03-12 | Dotter Charles T | Transluminally placed expandable graft prosthesis |
US5275622A (en) * | 1983-12-09 | 1994-01-04 | Harrison Medical Technologies, Inc. | Endovascular grafting apparatus, system and method and devices for use therewith |
US4580568A (en) * | 1984-10-01 | 1986-04-08 | Cook, Incorporated | Percutaneous endovascular stent and method for insertion thereof |
SE450809B (en) * | 1985-04-10 | 1987-08-03 | Medinvent Sa | PLANT TOPIC PROVIDED FOR MANUFACTURING A SPIRAL SPRING SUITABLE FOR TRANSLUMINAL IMPLANTATION AND MANUFACTURED SPIRAL SPRINGS |
US4733665C2 (en) * | 1985-11-07 | 2002-01-29 | Expandable Grafts Partnership | Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft |
US5102417A (en) * | 1985-11-07 | 1992-04-07 | Expandable Grafts Partnership | Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft |
US4800882A (en) * | 1987-03-13 | 1989-01-31 | Cook Incorporated | Endovascular stent and delivery system |
US4907336A (en) * | 1987-03-13 | 1990-03-13 | Cook Incorporated | Method of making an endovascular stent and delivery system |
US5041126A (en) * | 1987-03-13 | 1991-08-20 | Cook Incorporated | Endovascular stent and delivery system |
US4969458A (en) * | 1987-07-06 | 1990-11-13 | Medtronic, Inc. | Intracoronary stent and method of simultaneous angioplasty and stent implant |
US5131908A (en) * | 1987-09-01 | 1992-07-21 | Herbert Dardik | Tubular prosthesis for vascular reconstructive surgery and process for preparing same |
US4990131A (en) * | 1987-09-01 | 1991-02-05 | Herbert Dardik | Tubular prostheses for vascular reconstructive surgery and process for preparing same |
US4886062A (en) | 1987-10-19 | 1989-12-12 | Medtronic, Inc. | Intravascular radially expandable stent and method of implant |
US5133732A (en) * | 1987-10-19 | 1992-07-28 | Medtronic, Inc. | Intravascular stent |
US5266073A (en) * | 1987-12-08 | 1993-11-30 | Wall W Henry | Angioplasty stent |
US5192307A (en) * | 1987-12-08 | 1993-03-09 | Wall W Henry | Angioplasty stent |
CA1322628C (en) * | 1988-10-04 | 1993-10-05 | Richard A. Schatz | Expandable intraluminal graft |
US4856516A (en) * | 1989-01-09 | 1989-08-15 | Cordis Corporation | Endovascular stent apparatus and method |
CH678393A5 (en) * | 1989-01-26 | 1991-09-13 | Ulrich Prof Dr Med Sigwart | |
US5163958A (en) * | 1989-02-02 | 1992-11-17 | Cordis Corporation | Carbon coated tubular endoprosthesis |
US4990155A (en) * | 1989-05-19 | 1991-02-05 | Wilkoff Howard M | Surgical stent method and apparatus |
US4994071A (en) * | 1989-05-22 | 1991-02-19 | Cordis Corporation | Bifurcating stent apparatus and method |
US5015253A (en) * | 1989-06-15 | 1991-05-14 | Cordis Corporation | Non-woven endoprosthesis |
US5171262A (en) | 1989-06-15 | 1992-12-15 | Cordis Corporation | Non-woven endoprosthesis |
US5292331A (en) * | 1989-08-24 | 1994-03-08 | Applied Vascular Engineering, Inc. | Endovascular support device |
CA2026604A1 (en) * | 1989-10-02 | 1991-04-03 | Rodney G. Wolff | Articulated stent |
US5035706A (en) * | 1989-10-17 | 1991-07-30 | Cook Incorporated | Percutaneous stent and method for retrieval thereof |
US5176660A (en) * | 1989-10-23 | 1993-01-05 | Cordis Corporation | Catheter having reinforcing strands |
IL94138A (en) * | 1990-04-19 | 1997-03-18 | Instent Inc | Device for the treatment of constricted fluid conducting ducts |
US5064435A (en) * | 1990-06-28 | 1991-11-12 | Schneider (Usa) Inc. | Self-expanding prosthesis having stable axial length |
US5122154A (en) * | 1990-08-15 | 1992-06-16 | Rhodes Valentine J | Endovascular bypass graft |
US5222971A (en) * | 1990-10-09 | 1993-06-29 | Scimed Life Systems, Inc. | Temporary stent and methods for use and manufacture |
DE9117152U1 (en) * | 1990-10-09 | 1996-07-11 | Cook Inc | Stent |
US5449372A (en) * | 1990-10-09 | 1995-09-12 | Scimed Lifesystems, Inc. | Temporary stent and methods for use and manufacture |
US5217483A (en) * | 1990-11-28 | 1993-06-08 | Numed, Inc. | Intravascular radially expandable stent |
US5178618A (en) * | 1991-01-16 | 1993-01-12 | Brigham And Womens Hospital | Method and device for recanalization of a body passageway |
US5354257A (en) * | 1991-01-29 | 1994-10-11 | Med Institute, Inc. | Minimally invasive medical device for providing a radiation treatment |
US5135536A (en) * | 1991-02-05 | 1992-08-04 | Cordis Corporation | Endovascular stent and method |
US5116365A (en) * | 1991-02-22 | 1992-05-26 | Cordis Corporation | Stent apparatus and method for making |
US5304200A (en) * | 1991-05-29 | 1994-04-19 | Cordis Corporation | Welded radially expandable endoprosthesis and the like |
US5527354A (en) * | 1991-06-28 | 1996-06-18 | Cook Incorporated | Stent formed of half-round wire |
US5314472A (en) * | 1991-10-01 | 1994-05-24 | Cook Incorporated | Vascular stent |
USD359802S (en) * | 1991-06-28 | 1995-06-27 | Cook Incorporated | Vascular stent |
US5443498A (en) * | 1991-10-01 | 1995-08-22 | Cook Incorporated | Vascular stent and method of making and implanting a vacsular stent |
US5366504A (en) | 1992-05-20 | 1994-11-22 | Boston Scientific Corporation | Tubular medical prosthesis |
US5290305A (en) * | 1991-10-11 | 1994-03-01 | Kanji Inoue | Appliance collapsible for insertion into human organs and capable of resilient restoration |
US5387235A (en) * | 1991-10-25 | 1995-02-07 | Cook Incorporated | Expandable transluminal graft prosthesis for repair of aneurysm |
CA2380683C (en) * | 1991-10-28 | 2006-08-08 | Advanced Cardiovascular Systems, Inc. | Expandable stents and method for making same |
US5258021A (en) * | 1992-01-27 | 1993-11-02 | Duran Carlos G | Sigmoid valve annuloplasty ring |
CA2087132A1 (en) * | 1992-01-31 | 1993-08-01 | Michael S. Williams | Stent capable of attachment within a body lumen |
US5405377A (en) * | 1992-02-21 | 1995-04-11 | Endotech Ltd. | Intraluminal stent |
DE4206843C2 (en) * | 1992-03-04 | 1994-03-24 | Heraeus Elektrochemie | Electrochemical cells for performing electrochemical processes |
US5282823A (en) * | 1992-03-19 | 1994-02-01 | Medtronic, Inc. | Intravascular radially expandable stent |
US5370683A (en) | 1992-03-25 | 1994-12-06 | Cook Incorporated | Vascular stent |
FR2689388B1 (en) | 1992-04-07 | 1999-07-16 | Celsa Lg | PERFECTIONALLY RESORBABLE BLOOD FILTER. |
US5354308A (en) * | 1992-05-01 | 1994-10-11 | Beth Israel Hospital Association | Metal wire stent |
WO1995014500A1 (en) * | 1992-05-01 | 1995-06-01 | Beth Israel Hospital | A stent |
US5342387A (en) * | 1992-06-18 | 1994-08-30 | American Biomed, Inc. | Artificial support for a blood vessel |
US5496365A (en) * | 1992-07-02 | 1996-03-05 | Sgro; Jean-Claude | Autoexpandable vascular endoprosthesis |
US5382261A (en) * | 1992-09-01 | 1995-01-17 | Expandable Grafts Partnership | Method and apparatus for occluding vessels |
US5449382A (en) * | 1992-11-04 | 1995-09-12 | Dayton; Michael P. | Minimally invasive bioactivated endoprosthesis for vessel repair |
BE1006440A3 (en) * | 1992-12-21 | 1994-08-30 | Dereume Jean Pierre Georges Em | Luminal endoprosthesis AND METHOD OF PREPARATION. |
US5370691A (en) | 1993-01-26 | 1994-12-06 | Target Therapeutics, Inc. | Intravascular inflatable stent |
US5441515A (en) * | 1993-04-23 | 1995-08-15 | Advanced Cardiovascular Systems, Inc. | Ratcheting stent |
US5411549A (en) * | 1993-07-13 | 1995-05-02 | Scimed Life Systems, Inc. | Selectively expandable, retractable and removable stent |
US5723004A (en) * | 1993-10-21 | 1998-03-03 | Corvita Corporation | Expandable supportive endoluminal grafts |
US5389106A (en) * | 1993-10-29 | 1995-02-14 | Numed, Inc. | Impermeable expandable intravascular stent |
JP2703510B2 (en) * | 1993-12-28 | 1998-01-26 | アドヴァンスド カーディオヴァスキュラー システムズ インコーポレーテッド | Expandable stent and method of manufacturing the same |
US5403341A (en) * | 1994-01-24 | 1995-04-04 | Solar; Ronald J. | Parallel flow endovascular stent and deployment apparatus therefore |
US5609627A (en) * | 1994-02-09 | 1997-03-11 | Boston Scientific Technology, Inc. | Method for delivering a bifurcated endoluminal prosthesis |
US5443477A (en) * | 1994-02-10 | 1995-08-22 | Stentco, Inc. | Apparatus and method for deployment of radially expandable stents by a mechanical linkage |
US5643312A (en) * | 1994-02-25 | 1997-07-01 | Fischell Robert | Stent having a multiplicity of closed circular structures |
US5441516A (en) * | 1994-03-03 | 1995-08-15 | Scimed Lifesystems Inc. | Temporary stent |
US5449373A (en) * | 1994-03-17 | 1995-09-12 | Medinol Ltd. | Articulated stent |
US5397355A (en) * | 1994-07-19 | 1995-03-14 | Stentco, Inc. | Intraluminal stent |
US5609605A (en) * | 1994-08-25 | 1997-03-11 | Ethicon, Inc. | Combination arterial stent |
US6015429A (en) * | 1994-09-08 | 2000-01-18 | Gore Enterprise Holdings, Inc. | Procedures for introducing stents and stent-grafts |
CA2175720C (en) * | 1996-05-03 | 2011-11-29 | Ian M. Penn | Bifurcated stent and method for the manufacture and delivery of same |
CA2134997C (en) * | 1994-11-03 | 2009-06-02 | Ian M. Penn | Stent |
US5637113A (en) | 1994-12-13 | 1997-06-10 | Advanced Cardiovascular Systems, Inc. | Polymer film for wrapping a stent structure |
NL9500094A (en) * | 1995-01-19 | 1996-09-02 | Industrial Res Bv | Y-shaped stent and method of deployment. |
US5591197A (en) * | 1995-03-14 | 1997-01-07 | Advanced Cardiovascular Systems, Inc. | Expandable stent forming projecting barbs and method for deploying |
US5591228A (en) * | 1995-05-09 | 1997-01-07 | Edoga; John K. | Methods for treating abdominal aortic aneurysms |
US5669924A (en) * | 1995-10-26 | 1997-09-23 | Shaknovich; Alexander | Y-shuttle stent assembly for bifurcating vessels and method of using the same |
US5713854A (en) * | 1995-11-01 | 1998-02-03 | Cordis Corporation | Method and apparatus for dilatation catheterization |
US5690642A (en) * | 1996-01-18 | 1997-11-25 | Cook Incorporated | Rapid exchange stent delivery balloon catheter |
US6017363A (en) * | 1997-09-22 | 2000-01-25 | Cordis Corporation | Bifurcated axially flexible stent |
DE19614160A1 (en) * | 1996-04-10 | 1997-10-16 | Variomed Ag | Stent for transluminal implantation in hollow organs |
US6241760B1 (en) * | 1996-04-26 | 2001-06-05 | G. David Jang | Intravascular stent |
UA58485C2 (en) * | 1996-05-03 | 2003-08-15 | Медінол Лтд. | Method for manufacture of bifurcated stent (variants) and bifurcated stent (variants) |
US5697971A (en) | 1996-06-11 | 1997-12-16 | Fischell; Robert E. | Multi-cell stent with cells having differing characteristics |
US5728150A (en) * | 1996-07-29 | 1998-03-17 | Cardiovascular Dynamics, Inc. | Expandable microporous prosthesis |
US5749825A (en) * | 1996-09-18 | 1998-05-12 | Isostent, Inc. | Means method for treatment of stenosed arterial bifurcations |
US5720735A (en) * | 1997-02-12 | 1998-02-24 | Dorros; Gerald | Bifurcated endovascular catheter |
US5830229A (en) | 1997-03-07 | 1998-11-03 | Micro Therapeutics Inc. | Hoop stent |
US5893887A (en) * | 1997-10-14 | 1999-04-13 | Iowa-India Investments Company Limited | Stent for positioning at junction of bifurcated blood vessel and method of making |
DE19753123B4 (en) * | 1997-11-29 | 2006-11-09 | B. Braun Melsungen Ag | stent |
US5911754A (en) * | 1998-07-24 | 1999-06-15 | Uni-Cath Inc. | Flexible stent with effective strut and connector patterns |
US6190403B1 (en) * | 1998-11-13 | 2001-02-20 | Cordis Corporation | Low profile radiopaque stent with increased longitudinal flexibility and radial rigidity |
AU4924500A (en) * | 1999-05-19 | 2000-12-12 | Malte Neuss | Radially expandable vessel support |
US6312459B1 (en) * | 1999-06-30 | 2001-11-06 | Advanced Cardiovascular Systems, Inc. | Stent design for use in small vessels |
US7070614B1 (en) * | 2000-05-22 | 2006-07-04 | Malte Neuss | Radially expandable vessel support |
-
2002
- 2002-01-25 US US10/056,725 patent/US7029493B2/en not_active Expired - Lifetime
-
2003
- 2003-01-13 AU AU2003200088A patent/AU2003200088A1/en not_active Abandoned
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- 2003-01-21 DE DE60332184T patent/DE60332184D1/en not_active Expired - Lifetime
- 2003-01-21 AT AT03250363T patent/ATE464857T1/en not_active IP Right Cessation
- 2003-01-24 CA CA002417315A patent/CA2417315A1/en not_active Abandoned
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US20030144726A1 (en) | 2003-07-31 |
AU2003200088A1 (en) | 2003-08-14 |
ATE464857T1 (en) | 2010-05-15 |
EP1346706B1 (en) | 2010-04-21 |
DE60332184D1 (en) | 2010-06-02 |
EP1346706A1 (en) | 2003-09-24 |
US7029493B2 (en) | 2006-04-18 |
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EEER | Examination request | ||
FZDE | Discontinued |