CA2407279A1 - Medicament dispensing device with a multimaterial diaphragm bounding a pneumatic force chamber - Google Patents

Medicament dispensing device with a multimaterial diaphragm bounding a pneumatic force chamber Download PDF

Info

Publication number
CA2407279A1
CA2407279A1 CA002407279A CA2407279A CA2407279A1 CA 2407279 A1 CA2407279 A1 CA 2407279A1 CA 002407279 A CA002407279 A CA 002407279A CA 2407279 A CA2407279 A CA 2407279A CA 2407279 A1 CA2407279 A1 CA 2407279A1
Authority
CA
Canada
Prior art keywords
resisting force
dispensing device
force chamber
pneumatic force
medicament dispensing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002407279A
Other languages
French (fr)
Other versions
CA2407279C (en
Inventor
Michael Holroyd
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norton Healthcare Ltd
Original Assignee
Michael Holroyd
Norton Healthcare Ltd.
Norton Healthcare Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Michael Holroyd, Norton Healthcare Ltd., Norton Healthcare Limited filed Critical Michael Holroyd
Priority to CA2585995A priority Critical patent/CA2585995C/en
Publication of CA2407279A1 publication Critical patent/CA2407279A1/en
Application granted granted Critical
Publication of CA2407279C publication Critical patent/CA2407279C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0096—Hindering inhalation before activation of the dispenser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0093—Inhalators mechanically breath-triggered without arming or cocking, e.g. acting directly on the delivery valve
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor

Abstract

A metered dose inhaler for use with a pressurized aerosol container (25) which is preferably breath-actuated. A
preload (460) is applied to the internal aerosol valve by an amount sufficient to result in a dose release, but this is prevented by the application of a pneumatic resisting force. The inhaler comprises a release device (520) which, upon actuation, releases the resisting force and allows the preload to actuate the aerosol valve. A
metered dose of medicament is then released for inhalation by the patient. The pneumatic resisting force is established by a negative pressure region (600) defined in part by a diaphragm (440). The diaphragm (440) includes a central disk (441) of a first, relatively high stiffness material "A" and a peripheral ring, coupled by a flexure of a second, relatively low stiffness material "B".
CA002407279A 2000-06-09 2001-06-08 Medicament dispensing device with a multimaterial diaphragm bounding a pneumatic force chamber Expired - Lifetime CA2407279C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2585995A CA2585995C (en) 2000-06-09 2001-06-08 Multimaterial diaphragm

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/591,321 2000-06-09
US09/591,321 US6553988B1 (en) 2000-06-09 2000-06-09 Medicament dispensing device with a multimaterial diaphragm bounding a pneumatic force chamber
PCT/US2001/018664 WO2001093933A2 (en) 2000-06-09 2001-06-08 Medicament dispensing device with a multimaterial diaphragm bounding a pneumatic force chamber

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2585995A Division CA2585995C (en) 2000-06-09 2001-06-08 Multimaterial diaphragm

Publications (2)

Publication Number Publication Date
CA2407279A1 true CA2407279A1 (en) 2001-12-13
CA2407279C CA2407279C (en) 2007-08-14

Family

ID=24366021

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2585995A Expired - Lifetime CA2585995C (en) 2000-06-09 2001-06-08 Multimaterial diaphragm
CA002407279A Expired - Lifetime CA2407279C (en) 2000-06-09 2001-06-08 Medicament dispensing device with a multimaterial diaphragm bounding a pneumatic force chamber

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA2585995A Expired - Lifetime CA2585995C (en) 2000-06-09 2001-06-08 Multimaterial diaphragm

Country Status (17)

Country Link
US (3) US6553988B1 (en)
EP (1) EP1289589B1 (en)
JP (2) JP2003534882A (en)
KR (1) KR100528375B1 (en)
AR (2) AR028689A1 (en)
AT (1) ATE274954T1 (en)
AU (2) AU2001266806B2 (en)
CA (2) CA2585995C (en)
DE (1) DE60105291T2 (en)
DK (1) DK1289589T3 (en)
ES (1) ES2228890T3 (en)
GB (1) GB2366207A (en)
PE (1) PE20020185A1 (en)
PT (1) PT1289589E (en)
SI (1) SI1289589T1 (en)
TW (1) TW493997B (en)
WO (1) WO2001093933A2 (en)

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US20170304459A1 (en) 2014-10-10 2017-10-26 Alnylam Pharmaceuticals, Inc. Methods and compositions for inhalation delivery of conjugated oligonucleotide
US20170348496A1 (en) * 2014-12-17 2017-12-07 Norton (Waterford) Limited Can and Actuator Assembly
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GB201702407D0 (en) * 2017-02-14 2017-03-29 Norton (Waterford) Ltd Inhalers and related methods
GB201702408D0 (en) 2017-02-14 2017-03-29 Norton (Waterford) Ltd Inhalers and related methods
GB201702406D0 (en) 2017-02-14 2017-03-29 Norton (Waterford) Ltd Inhalers and related methods
GB201801309D0 (en) 2018-01-26 2018-03-14 Norton Waterford Ltd Breath actuated inhaler
WO2023094551A1 (en) 2021-11-24 2023-06-01 Norton (Waterford) Limited Drug delivery device with electronics
KR20230163797A (en) * 2022-05-24 2023-12-01 주식회사 케이티앤지 Inhaler

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Also Published As

Publication number Publication date
AU2001266806B2 (en) 2005-03-10
DE60105291T2 (en) 2005-09-15
US7637260B2 (en) 2009-12-29
EP1289589A2 (en) 2003-03-12
GB0114046D0 (en) 2001-08-01
US20040025867A1 (en) 2004-02-12
GB2366207A (en) 2002-03-06
WO2001093933A3 (en) 2002-03-14
ATE274954T1 (en) 2004-09-15
US20100065050A1 (en) 2010-03-18
US6553988B1 (en) 2003-04-29
DE60105291D1 (en) 2004-10-07
JP2003534882A (en) 2003-11-25
KR100528375B1 (en) 2005-11-15
JP2008296062A (en) 2008-12-11
WO2001093933A2 (en) 2001-12-13
EP1289589B1 (en) 2004-09-01
AR028689A1 (en) 2003-05-21
CA2407279C (en) 2007-08-14
JP5069653B2 (en) 2012-11-07
PT1289589E (en) 2004-12-31
AU6680601A (en) 2001-12-17
CA2585995A1 (en) 2001-12-13
DK1289589T3 (en) 2005-01-17
SI1289589T1 (en) 2005-02-28
KR20030028737A (en) 2003-04-10
PE20020185A1 (en) 2002-02-23
TW493997B (en) 2002-07-11
US8225780B2 (en) 2012-07-24
ES2228890T3 (en) 2005-04-16
CA2585995C (en) 2012-08-21
AR064324A2 (en) 2009-03-25

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Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20210608