CA2403615A1 - Pre-filled syringe - Google Patents

Pre-filled syringe Download PDF

Info

Publication number
CA2403615A1
CA2403615A1 CA002403615A CA2403615A CA2403615A1 CA 2403615 A1 CA2403615 A1 CA 2403615A1 CA 002403615 A CA002403615 A CA 002403615A CA 2403615 A CA2403615 A CA 2403615A CA 2403615 A1 CA2403615 A1 CA 2403615A1
Authority
CA
Canada
Prior art keywords
medical liquid
hole
barrel
sealing member
filled syringe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002403615A
Other languages
French (fr)
Other versions
CA2403615C (en
Inventor
Malcolm John Henderson
Toshikazu Hirayama
Masafumi Aramata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aspen Global Inc
Original Assignee
Astrazeneca Uk Limited
Malcolm John Henderson
Toshikazu Hirayama
Masafumi Aramata
Aspen Global Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Uk Limited, Malcolm John Henderson, Toshikazu Hirayama, Masafumi Aramata, Aspen Global Incorporated filed Critical Astrazeneca Uk Limited
Publication of CA2403615A1 publication Critical patent/CA2403615A1/en
Application granted granted Critical
Publication of CA2403615C publication Critical patent/CA2403615C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/28Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • A61M5/3134Syringe barrels characterised by constructional features of the distal end, i.e. end closest to the tip of the needle cannula
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A61M5/344Constructions for connecting the needle, e.g. to syringe nozzle or needle hub using additional parts, e.g. clamping rings or collets
    • A61M5/345Adaptors positioned between needle hub and syringe nozzle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M2005/3103Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3104Caps for syringes without needle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M2005/3103Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3106Plugs for syringes without needle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M2005/3117Means preventing contamination of the medicament compartment of a syringe
    • A61M2005/3118Means preventing contamination of the medicament compartment of a syringe via the distal end of a syringe, i.e. syringe end for mounting a needle cannula

Abstract

A pre-filled syringe comprising a glass barrel (1), a sealing member (5) fitted in a medical liquid discharge port (11) of the barrel (1), a tip member (2) mounted around the sealing member (5) on the medical liquid discharge port (11) of the barrel (1), a closing member (4), a cap member (3), and a holding member (6); the sealing member (5) having a through-hole (51) formed in the axial direction; the tip member (2) including a skirt (24) provided with an engagement pawl (25) on the inner wall of a lower end thereof, a top wall (23), a needle mounting portion (21), and a medical liquid deriving portion (22), and being provided with a medical liquid passage (28); the closing member (4) being inserted into the medical liquid passage (28) and the through-hole (51) to close the through-hole (51) and so prevent oxygen contamination and deterioration of the medical liquid.
CA002403615A 2000-04-03 2001-03-28 Pre-filled syringe Expired - Lifetime CA2403615C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000-105386 2000-04-03
JP2000105386A JP3591636B2 (en) 2000-04-03 2000-04-03 Prefilled syringe
PCT/GB2001/001433 WO2001074424A2 (en) 2000-04-03 2001-03-28 Pre-filled syringe

Publications (2)

Publication Number Publication Date
CA2403615A1 true CA2403615A1 (en) 2001-10-11
CA2403615C CA2403615C (en) 2009-03-24

Family

ID=18618757

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002403615A Expired - Lifetime CA2403615C (en) 2000-04-03 2001-03-28 Pre-filled syringe

Country Status (18)

Country Link
US (1) US7041087B2 (en)
EP (1) EP1276525B1 (en)
JP (1) JP3591636B2 (en)
KR (1) KR100720640B1 (en)
CN (1) CN1222328C (en)
AT (1) ATE304379T1 (en)
AU (2) AU4263601A (en)
BR (1) BR0109735B1 (en)
CA (1) CA2403615C (en)
DE (1) DE60113399T2 (en)
DK (1) DK1276525T3 (en)
ES (1) ES2247080T3 (en)
IL (2) IL151930A0 (en)
MX (1) MXPA02009726A (en)
NO (1) NO330573B1 (en)
NZ (1) NZ521562A (en)
WO (1) WO2001074424A2 (en)
ZA (1) ZA200207929B (en)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1441789B1 (en) * 2001-10-12 2009-07-01 Felton International, Inc. Universal protector cap with auto-disable features for needle-free injectors
US20050075611A1 (en) * 2003-10-01 2005-04-07 Hetzler Kevin G. Low extractable, thermoplastic syringe and tip cap
EP1986926B1 (en) * 2006-02-14 2010-10-27 Arzneimittel GmbH Apotheker Vetter & Co. Ravensburg Syringe
WO2007131086A2 (en) * 2006-05-05 2007-11-15 Retractable Technologies, Inc. Syringe with recessed nose for use with frontal attachments
US9295790B2 (en) * 2006-05-05 2016-03-29 Retractable Technologies, Inc. Syringe with recessed nose and protective guard for use with frontal attachments
ES2425579T3 (en) 2006-05-25 2013-10-16 Bayer Healthcare, Llc Reconstitution device
US7981090B2 (en) 2006-10-18 2011-07-19 Baxter International Inc. Luer activated device
US8221363B2 (en) 2006-10-18 2012-07-17 Baxter Healthcare S.A. Luer activated device with valve element under tension
US7753338B2 (en) 2006-10-23 2010-07-13 Baxter International Inc. Luer activated device with minimal fluid displacement
WO2008098860A1 (en) * 2007-02-14 2008-08-21 Shl Medical Ab Container for a medical device
JP5074581B2 (en) * 2007-06-01 2012-11-14 ウノメディカル・アー/エス Urine meter and hose connection
ES2679674T3 (en) 2008-01-11 2018-08-30 Ucb Biopharma Sprl Systems for administering medication for patients with rheumatoid arthritis
USD641078S1 (en) 2008-12-29 2011-07-05 Ucb Pharma, S.A. Medical syringe with needle tip cap
ES2757821T3 (en) 2008-07-18 2020-04-30 UCB Biopharma SRL Medication Delivery Systems for Rheumatoid Arthritis Patients
AU2009307960A1 (en) 2008-10-22 2010-04-29 Thomas J. Shaw Universal syringe with retractable needle
ES2719496T3 (en) 2008-11-12 2019-07-10 Medimmune Llc Antibody formulation
DE102009007250A1 (en) * 2009-01-26 2010-07-29 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg syringe
USD660958S1 (en) 2009-07-20 2012-05-29 Ucb Pharma, S.A. Device for administering medication
US9480801B2 (en) * 2009-08-21 2016-11-01 Becton Dickinson France Tamper evident tip cap and syringe
JP5779173B2 (en) * 2010-03-03 2015-09-16 テルモ株式会社 Syringe
WO2012022734A2 (en) 2010-08-16 2012-02-23 Medimmune Limited Anti-icam-1 antibodies and methods of use
WO2012110057A1 (en) 2011-02-15 2012-08-23 Chemisches Institut Schaefer Ag Cefuroxime safety kit
CA2828904A1 (en) * 2011-03-03 2012-09-07 Vetter Pharma-Fertigung GmbH & Co. KG Closure for a syringe and method for producing same
DE102011013792A1 (en) * 2011-03-03 2012-09-06 Vetter Pharma-Fertigung GmbH & Co. KG Closure for a powder syringe and powder syringe
JP5798872B2 (en) * 2011-10-03 2015-10-21 大成化工株式会社 Cap, barrel with cap, and prefilled syringe
JP6339558B2 (en) * 2012-04-05 2018-06-06 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Pen syringe
US9181572B2 (en) 2012-04-20 2015-11-10 Abbvie, Inc. Methods to modulate lysine variant distribution
WO2013176754A1 (en) 2012-05-24 2013-11-28 Abbvie Inc. Novel purification of antibodies using hydrophobic interaction chromatography
ES2599508T3 (en) * 2012-09-26 2017-02-02 Transcoject Gmbh Prefilled syringe
CN102961803B (en) * 2012-10-30 2015-01-21 无锡耐思生物科技有限公司 Disposable prefilled syringe
DE102012022008A1 (en) * 2012-11-09 2014-05-15 Vetter Pharma-Fertigung GmbH & Co. KG syringe closure
ES2882063T3 (en) 2012-12-03 2021-12-01 Novobiotic Pharmaceuticals Llc New depsipeptide and its uses
CA2926384A1 (en) 2013-03-14 2014-10-02 Abbvie Inc. Low acidic species compositions and methods for producing and using the same
AU2014240431A1 (en) 2013-03-14 2015-08-27 Abbvie Inc. Low acidic species compositions and methods for producing the same using displacement chromatography
ES2933549T3 (en) 2013-07-10 2023-02-10 Matrix Biology Inst Hyaluronan compositions with high elasticity and uses thereof
WO2015021261A1 (en) * 2013-08-07 2015-02-12 Unitract Syringe Pty Ltd Luer connection adapters for retractable needle syringes
JP2016528996A (en) 2013-08-07 2016-09-23 ユニトラクト シリンジ プロプライエタリイ リミテッドUnitract Syringe Pty Ltd Luer connection adapter for syringe
WO2015033954A1 (en) * 2013-09-06 2015-03-12 テルモ株式会社 Outer tube for syringe and pre-filled syringe
WO2015050959A1 (en) 2013-10-01 2015-04-09 Yale University Anti-kit antibodies and methods of use thereof
US20170226552A1 (en) 2014-07-03 2017-08-10 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using cobalt
US20160185848A1 (en) 2014-07-09 2016-06-30 Abbvie Inc. Methods for modulating the glycosylation profile of recombinant proteins using sugars
WO2016144773A1 (en) 2015-03-06 2016-09-15 Abbvie Inc. Arabinosylated glycoproteins
EP3842047A1 (en) 2015-09-24 2021-06-30 Matrix Biology Institute High elasticity hyaluronan compositions and methods of use thereof
WO2017147003A1 (en) 2016-02-26 2017-08-31 Novobiotic Pharmaceuticals, Llc Novel macrocyclic antibiotics and uses thereof
WO2018077575A1 (en) * 2016-10-24 2018-05-03 Medmix Systems Ag Modular discharge device with separator element
CH713067A1 (en) * 2016-10-24 2018-04-30 Medmix Systems Ag Modular discharge device with separating element.
EP3603603A4 (en) * 2017-03-22 2020-12-30 Terumo Kabushiki Kaisha Female syringe and syringe kit
JP7194115B2 (en) 2017-04-04 2022-12-21 ノボバイオティック ファーマシューティカルズ, エルエルシー Novel depsipeptides and uses thereof
AU2018251806B2 (en) 2017-04-12 2023-05-25 Urigen Pharmaceuticals, Inc. Article of manufacture comprising local anesthetic, buffer, and glycosaminoglycan in syringe with improved stability
HUE057779T2 (en) * 2019-03-29 2022-06-28 Kortuc Inc Hydrogen peroxide solution-prefilled syringe having excellent hydrogen peroxide preservability by virtue of silicone oil (oil composition containing said silicone oil)
EP4010051A4 (en) * 2019-08-06 2023-08-02 MicroVention, Inc. Syringe
JP2022012330A (en) * 2020-07-01 2022-01-17 テルモ株式会社 Prefilled syringe, syringe assembly, method for manufacturing prefilled syringe and method for increasing surface area
WO2022045654A1 (en) * 2020-08-25 2022-03-03 김용현 Method for manufacturing pre-filled medicinal liquid pumping assembly, pre-filled medicinal liquid pumping assembly and pre-filled medicinal liquid injection apparatus
KR102558992B1 (en) * 2020-08-25 2023-07-25 김용현 Medicinal liquid pumping apparatus and preparing method for medicinal liquid injection using the same
WO2023163243A1 (en) * 2022-02-23 2023-08-31 김용현 Method for manufacturing pre-filled medicinal liquid pumping assembly, pre-filled medicinal liquid pumping assembly, and pre-filled medicinal liquid injection set

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2388634A (en) * 1944-12-07 1945-11-06 Ace Glass Inc Container for aseptic filling and dispensing of sterile liquids
US2659370A (en) * 1950-08-26 1953-11-17 Arthur E Smith Closure
US2677374A (en) * 1952-11-07 1954-05-04 Lilly Co Eli Syringe closure
US3989044A (en) * 1975-08-11 1976-11-02 Warner-Lambert Company Syringe
US4253459A (en) * 1979-11-19 1981-03-03 Aluminum Company Of America Additive transfer unit with stabilized sealing means
US4781701A (en) * 1986-07-11 1988-11-01 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Syringe for medical purposes
ES2056244T3 (en) * 1989-05-17 1994-10-01 Vetter & Co Apotheker SYRINGE FOR MEDICAL APPLICATIONS.
DE4127650C1 (en) 1991-08-21 1993-02-25 Arzneimittel Gmbh Apotheker Vetter & Co Ravensburg, 7980 Ravensburg, De
JP3097798B2 (en) 1993-09-10 2000-10-10 株式会社ニッショー Drug-filled syringe
JP3383966B2 (en) 1994-05-27 2003-03-10 ニプロ株式会社 Prefilled syringe
AUPM922394A0 (en) * 1994-11-03 1994-11-24 Astra Pharmaceuticals Pty Ltd Plastic syringe with overcap
US5501676A (en) * 1995-01-13 1996-03-26 Sanofi Winthrop, Inc. Coupling system for safety cannula
US5807345A (en) 1995-06-30 1998-09-15 Abbott Laboratories Luer cap for terminally sterilized syringe
DE19537163C1 (en) * 1995-10-06 1997-01-30 Vetter & Co Apotheker Syringe for medical purposes
DE19638940C2 (en) * 1996-09-23 1999-01-07 Vetter & Co Apotheker Prefilled syringe for medical purposes

Also Published As

Publication number Publication date
CN1222328C (en) 2005-10-12
MXPA02009726A (en) 2003-03-27
EP1276525A2 (en) 2003-01-22
AU2001242636B2 (en) 2005-04-28
DK1276525T3 (en) 2005-11-21
BR0109735A (en) 2003-02-04
IL151930A (en) 2007-06-17
CN1422167A (en) 2003-06-04
ES2247080T3 (en) 2006-03-01
NO20024469D0 (en) 2002-09-18
ATE304379T1 (en) 2005-09-15
JP2001276220A (en) 2001-10-09
JP3591636B2 (en) 2004-11-24
US7041087B2 (en) 2006-05-09
CA2403615C (en) 2009-03-24
DE60113399D1 (en) 2005-10-20
NZ521562A (en) 2004-03-26
KR100720640B1 (en) 2007-05-21
ZA200207929B (en) 2003-07-17
EP1276525B1 (en) 2005-09-14
NO20024469L (en) 2002-11-26
BR0109735B1 (en) 2010-08-24
WO2001074424A3 (en) 2001-12-20
IL151930A0 (en) 2003-04-10
US20040087906A1 (en) 2004-05-06
DE60113399T2 (en) 2006-06-22
NO330573B1 (en) 2011-05-16
WO2001074424A2 (en) 2001-10-11
KR20030016242A (en) 2003-02-26
AU4263601A (en) 2001-10-15

Similar Documents

Publication Publication Date Title
CA2403615A1 (en) Pre-filled syringe
US5624402A (en) Syringe tip cap
US6632199B1 (en) Syringe assembly including plastic tip cap
SA109300578B1 (en) Cap Assembly and Production Method
US6520935B1 (en) Syringe and tip cap assembly
WO1999052578A3 (en) Syringe assembly
WO2003045478A1 (en) Two-chamber type prefilled syringe
CA2506998A1 (en) Prefilled syringe
CA2243408A1 (en) Sealing rubber closure for syringe/container
HK1089651A1 (en) Ampoule
US20030018308A1 (en) Drug-adding tube of infusion set
US5695465A (en) Syringe containing drug to be injected
WO2003015854A1 (en) Two-chamber type prefilled syringe
CA2299728A1 (en) Medical syringe and assembly procedure
EP0687477A4 (en) Drug-containing syringe
CA2345005A1 (en) Container for intravenous administration
WO2000053241A3 (en) Syringe device
JP2001158449A (en) Bottle plug and check valve device for pouring and sucking liquid from bottle
JPH07136264A (en) Two-components mixing prefilled injector
US20020138046A1 (en) Adapter for medication cartridges
CA1170941A (en) Anesthesia device
JPH08117334A (en) Kit for mixing
JPH0698935A (en) Liquid drug packed injector

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20210329