CA2403114A1 - Mass labels - Google Patents

Mass labels Download PDF

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Publication number
CA2403114A1
CA2403114A1 CA002403114A CA2403114A CA2403114A1 CA 2403114 A1 CA2403114 A1 CA 2403114A1 CA 002403114 A CA002403114 A CA 002403114A CA 2403114 A CA2403114 A CA 2403114A CA 2403114 A1 CA2403114 A1 CA 2403114A1
Authority
CA
Canada
Prior art keywords
mass
labels
label
group
different
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002403114A
Other languages
French (fr)
Other versions
CA2403114C (en
Inventor
Gunter Schmidt
Andrew Hugin Thompson
Robert Alexander Walker Johnstone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Electrophoretics Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9887608&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2403114(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CA2403114A1 publication Critical patent/CA2403114A1/en
Application granted granted Critical
Publication of CA2403114C publication Critical patent/CA2403114C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6872—Methods for sequencing involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/13—Tracers or tags

Abstract

Provided is a set of two or more mass labels, each label in the set comprising a mass marker moiety attached via a cleavable linker to a mass normalisation moiety, the mass marker moiety being fragmentation resistant, wherein the aggregate mass of each label in the set may be the same or different and the mass of the mass marker moiety of each label in the set may be the same or different, and wherein in any group of labels within the set having a mass marker moiety of a common mass each label has an aggregate mass different from all other labels in that group, and wherein in any group of labels within the set having a common aggregate mass each label has a mass marker moiety having a mass different from that of all other mass marker moieties in that group, such that all of the mass labels in the set are distinguishable from each other by mass spectrometry.
CA002403114A 2000-03-14 2001-03-14 Mass labels Expired - Lifetime CA2403114C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0006141.6 2000-03-14
GBGB0006141.6A GB0006141D0 (en) 2000-03-14 2000-03-14 Mass labels
PCT/GB2001/001122 WO2001068664A2 (en) 2000-03-14 2001-03-14 Mass labels

Publications (2)

Publication Number Publication Date
CA2403114A1 true CA2403114A1 (en) 2001-09-20
CA2403114C CA2403114C (en) 2007-07-31

Family

ID=9887608

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002403114A Expired - Lifetime CA2403114C (en) 2000-03-14 2001-03-14 Mass labels

Country Status (15)

Country Link
US (3) US7294456B2 (en)
EP (2) EP1806586B1 (en)
JP (1) JP4608171B2 (en)
CN (2) CN102839213A (en)
AT (1) ATE364841T1 (en)
AU (2) AU4083401A (en)
CA (1) CA2403114C (en)
DE (1) DE60128900T2 (en)
DK (1) DK1275004T3 (en)
ES (2) ES2287104T3 (en)
GB (1) GB0006141D0 (en)
IL (2) IL151732A0 (en)
NO (1) NO330733B1 (en)
PT (1) PT1275004E (en)
WO (1) WO2001068664A2 (en)

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Also Published As

Publication number Publication date
AU2001240834B2 (en) 2005-11-17
CN102839213A (en) 2012-12-26
US20030194717A1 (en) 2003-10-16
JP4608171B2 (en) 2011-01-05
ES2389510T3 (en) 2012-10-26
WO2001068664A3 (en) 2002-03-21
JP2003529059A (en) 2003-09-30
PT1275004E (en) 2007-08-14
ATE364841T1 (en) 2007-07-15
IL151732A0 (en) 2003-04-10
CN1427953A (en) 2003-07-02
EP1806586B1 (en) 2012-08-15
US7825069B2 (en) 2010-11-02
EP1806586A1 (en) 2007-07-11
EP1275004B1 (en) 2007-06-13
GB0006141D0 (en) 2000-05-03
NO330733B1 (en) 2011-06-27
US7294456B2 (en) 2007-11-13
WO2001068664A2 (en) 2001-09-20
US20080145850A1 (en) 2008-06-19
CN1427953B (en) 2012-08-29
DE60128900T2 (en) 2008-02-07
EP1275004A2 (en) 2003-01-15
AU4083401A (en) 2001-09-24
US20080167197A1 (en) 2008-07-10
NO20024344D0 (en) 2002-09-12
IL151732A (en) 2008-11-03
DE60128900D1 (en) 2007-07-26
DK1275004T3 (en) 2007-10-15
US7816304B2 (en) 2010-10-19
CA2403114C (en) 2007-07-31
ES2287104T3 (en) 2007-12-16
NO20024344L (en) 2002-11-14

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Effective date: 20210315