CA2373860A1 - Method and apparatus for non-invasive blood analyte measurement - Google Patents

Method and apparatus for non-invasive blood analyte measurement Download PDF

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Publication number
CA2373860A1
CA2373860A1 CA002373860A CA2373860A CA2373860A1 CA 2373860 A1 CA2373860 A1 CA 2373860A1 CA 002373860 A CA002373860 A CA 002373860A CA 2373860 A CA2373860 A CA 2373860A CA 2373860 A1 CA2373860 A1 CA 2373860A1
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CA
Canada
Prior art keywords
analyte
blood
concentration
fluid compartment
analyte measurement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002373860A
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French (fr)
Other versions
CA2373860C (en
Inventor
Mark Rohrscheib
Craig Gardner
Mark R. Robinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of New Mexico UNM
Rio Grande Medical Technologies Inc
Original Assignee
Rio Grande Medical Technologies, Inc.
Mark Rohrscheib
Craig Gardner
Mark R. Robinson
University Of New Mexico
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rio Grande Medical Technologies, Inc., Mark Rohrscheib, Craig Gardner, Mark R. Robinson, University Of New Mexico filed Critical Rio Grande Medical Technologies, Inc.
Publication of CA2373860A1 publication Critical patent/CA2373860A1/en
Application granted granted Critical
Publication of CA2373860C publication Critical patent/CA2373860C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/14—Coupling media or elements to improve sensor contact with skin or tissue
    • A61B2562/146—Coupling media or elements to improve sensor contact with skin or tissue for optical coupling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1495—Calibrating or testing of in-vivo probes

Abstract

A method and apparatus for non-invasively measuring the concentration of an analyte, particularly blood analyte in blood. The method utilizes spectographic techniques in conjunction with means for equilibrating the concentration of the analyte between the vascular system fluid compartment of the test area and the other tissue fluid compartment. An improved optical interface between a sensor probe and a skin surface or tissue surface of the body containing the blood to be analyzed. Multiple readings during the equilibration period are taken and utilized to show the direction and rate of charge of concentration of the analyte in the blood which is useful in optimizing therapeutic response to the collected data.
CA002373860A 1999-06-30 2000-06-12 Method and apparatus for non-invasive blood analyte measurement Expired - Fee Related CA2373860C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/343,800 US6240306B1 (en) 1995-08-09 1999-06-30 Method and apparatus for non-invasive blood analyte measurement with fluid compartment equilibration
US09/343,800 1999-06-30
PCT/US2000/016122 WO2001001852A1 (en) 1999-06-30 2000-06-12 Method and apparatus for non-invasive blood analyte measurement

Publications (2)

Publication Number Publication Date
CA2373860A1 true CA2373860A1 (en) 2001-01-11
CA2373860C CA2373860C (en) 2005-07-26

Family

ID=23347723

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002373860A Expired - Fee Related CA2373860C (en) 1999-06-30 2000-06-12 Method and apparatus for non-invasive blood analyte measurement

Country Status (10)

Country Link
US (2) US6240306B1 (en)
EP (1) EP1194067A1 (en)
JP (1) JP2004500155A (en)
KR (1) KR20020043458A (en)
CN (1) CN1230119C (en)
AU (1) AU5482900A (en)
CA (1) CA2373860C (en)
MX (1) MXPA02000157A (en)
NO (1) NO20016364L (en)
WO (1) WO2001001852A1 (en)

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NO20016364D0 (en) 2001-12-27
KR20020043458A (en) 2002-06-10
US6718189B2 (en) 2004-04-06
WO2001001852A1 (en) 2001-01-11
NO20016364L (en) 2002-02-26
AU5482900A (en) 2001-01-22
CA2373860C (en) 2005-07-26
EP1194067A1 (en) 2002-04-10
CN1399527A (en) 2003-02-26
MXPA02000157A (en) 2002-07-30
JP2004500155A (en) 2004-01-08
US20020035341A1 (en) 2002-03-21
US6240306B1 (en) 2001-05-29

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