CA2367351A1 - Intraluminal lining - Google Patents

Intraluminal lining Download PDF

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Publication number
CA2367351A1
CA2367351A1 CA002367351A CA2367351A CA2367351A1 CA 2367351 A1 CA2367351 A1 CA 2367351A1 CA 002367351 A CA002367351 A CA 002367351A CA 2367351 A CA2367351 A CA 2367351A CA 2367351 A1 CA2367351 A1 CA 2367351A1
Authority
CA
Canada
Prior art keywords
prosthesis
liner
adhesive
tubular body
intraluminal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002367351A
Other languages
French (fr)
Other versions
CA2367351C (en
Inventor
Kristian Dimatteo
Adrian Ravenscroft
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Scientific Ltd Barbados
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2367351A1 publication Critical patent/CA2367351A1/en
Application granted granted Critical
Publication of CA2367351C publication Critical patent/CA2367351C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A61F2002/072—Encapsulated stents, e.g. wire or whole stent embedded in lining
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A61F2002/075—Stent-grafts the stent being loosely attached to the graft material, e.g. by stitching
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/005—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using adhesives

Abstract

The present invention is directed to a prosthesis for implantation within a body lumen. The prosthesis includes a biocompatible elongate intraluminal liner in the form of a graft, with a biocompatible adhesive being disposed on an exterior surface of the graft. The adhesive is active in an intraluminal environment so as to bond the exterior surface of the graft to an intraluminal surface of said body lumen, such as the interior of a blood vessel.

Claims (30)

1. A prosthesis for implantation within a body lumen, comprising:
a biocompatible elongate intraluminal liner, said liner including an elongate tubular body having an interior surface and an exterior surface; and a biocompatible adhesive, said adhesive being disposed on said exterior surface of said liner, said adhesive being active in an intraluminal environment so as to bond said exterior surface of said liner to an intraluminal surface of said body lumen.
2. The prosthesis of claim 1, wherein said adhesive is bioabsorbable.
3. The prosthesis of claim 1, wherein said adhesive is a curable polymer adhesive.
4. The prosthesis of claim 1, wherein said adhesive is a pressure sensitive adhesive.
5. The prosthesis of claim 1, wherein said adhesive is selected from the group consisting of polyurethanes, cyanoacrylates, silicones, (meth)acrylates, and combinations thereof.
6. The prosthesis of claim 1, wherein said adhesive is a biological sealant capable of bonding said liner to said intraluminal surface of said body lumen.
7. The prosthesis of claim 6, wherein said biological sealant is selected from the group consisting of fibrin, collagen, poly(L-glutamic acid), gelatin based hydrogels, N-vinyl pyrrolidone, and mixtures and combinations thereof.
8. The prosthesis of claim 1, wherein said adhesive is held within frangible encapsulants, said encapsulants being disposed on said exterior surface of said tubular body and being capable of rupturing when compressed between said tubular body and said lumen so as to release said adhesive and thereby bonding said exterior surface of said liner to an intraluminal surface of said body lumen.
9. The prosthesis of claim 1, wherein said liner includes a plurality of pores sufficient to permit the ingrowth of body tissue.
10. The prosthesis of claim 9, wherein said adhesive is disposed through at least one of said pores in said liner.
11. The prosthesis of claim 1, further comprising a mechanical support disposed along said interior surface of said tubular body to maintain said tubular body in an open position.
12. The prosthesis of claim 11, wherein said mechanical support is removable from said tubular body.
13. The prosthesis of claim 11, wherein said mechanical support is bioabsorbable.
14. The prosthesis of claim 11, wherein said mechanical support is positioned at least one longitudinal end of said tubular body.
15. The prosthesis of claim 11, wherein said mechanical support is positioned at an upstream end of said tubular body.
16. The prosthesis of claim 11, wherein said mechanical support is provided at both longitudinal ends of said tubular body.
17. The prosthesis of claim 11, wherein said adhesive extends through said pores and bonds said mechanical support to said liner.
18. The prosthesis of claim 11, wherein said mechanical support comprises a radially expandable stent.
19. The prosthesis of claim 11, wherein said mechanical support comprises a porous polymeric band.
20. The prosthesis of claim 1, wherein said liner comprises an extruded tube.
21. The prosthesis of claim 1, wherein said liner is formed from a polymeric sheet.
22. The prosthesis of claim 1, wherein said liner comprises a textile tubular body.
23. The prosthesis of claim 22, wherein said textile tubular body is formed from a weave, knit, or braid construction.
24. The prosthesis of claim 1, wherein said tubular body is formed from spun filaments.
25. The prosthesis of claim 1, wherein said liner is formed from a material selected from the group consisting of polyesters, polypropylenes, polyethylenes, polyurethanes, polytetrafluoroethylenes, polycarbonate-polyurethanes, poly-alpha-hydroxy-acids, and combinations thereof.
26. The prosthesis of claim 1, wherein said liner is expandable from an insertion diameter to an implantation diameter greater than said insertion diameter so that at the implantation diameter said liner is conformable to the intraluminal surface of said body lumen.
27. The prosthesis of claim 1, further including a removable cover over said adhesive.
28. The prosthesis of claim 1, further including a concentric tubular body within said liner.
29. The prosthesis of claim 28, further including a mechanical support between said concentric tubular body and said liner.
30. A method of adhering an intraluminal liner to a venal wall comprising the steps of:
providing a prosthesis comprising an intraluminal liner including a biocompatible adhesive disposed on an exterior surface of said liner, said biocompatible adhesive being active in an intraluminal environment;
delivering said prosthesis to an area of implantation; and expanding said prosthesis so as to cause said adhesive on said exterior surface of said liner to contact an interior surface of the venal wall, thereby causing said adhesive to bond said prosthesis to said venal wall.
CA2367351A 1999-04-01 2000-03-31 Intraluminal lining Expired - Fee Related CA2367351C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/283,556 US6312457B1 (en) 1999-04-01 1999-04-01 Intraluminal lining
US09/283,556 1999-04-01
PCT/US2000/008817 WO2000059558A1 (en) 1999-04-01 2000-03-31 Intraluminal lining

Publications (2)

Publication Number Publication Date
CA2367351A1 true CA2367351A1 (en) 2000-10-12
CA2367351C CA2367351C (en) 2011-05-17

Family

ID=23086600

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2367351A Expired - Fee Related CA2367351C (en) 1999-04-01 2000-03-31 Intraluminal lining

Country Status (7)

Country Link
US (4) US6312457B1 (en)
EP (2) EP1171177B1 (en)
JP (1) JP2002540854A (en)
AU (1) AU4065800A (en)
CA (1) CA2367351C (en)
DE (2) DE60032758T2 (en)
WO (1) WO2000059558A1 (en)

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