CA2353948A1 - Needleless syringe with prefilled cartridge - Google Patents

Needleless syringe with prefilled cartridge Download PDF

Info

Publication number
CA2353948A1
CA2353948A1 CA002353948A CA2353948A CA2353948A1 CA 2353948 A1 CA2353948 A1 CA 2353948A1 CA 002353948 A CA002353948 A CA 002353948A CA 2353948 A CA2353948 A CA 2353948A CA 2353948 A1 CA2353948 A1 CA 2353948A1
Authority
CA
Canada
Prior art keywords
valve
cartridge
disposed
nozzle
rearward
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002353948A
Other languages
French (fr)
Other versions
CA2353948C (en
Inventor
Sergio Landau
James M. Bonicatto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioject Inc
Original Assignee
Bioject, Inc.
Sergio Landau
James M. Bonicatto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioject, Inc., Sergio Landau, James M. Bonicatto filed Critical Bioject, Inc.
Publication of CA2353948A1 publication Critical patent/CA2353948A1/en
Application granted granted Critical
Publication of CA2353948C publication Critical patent/CA2353948C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
    • A61M5/2459—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst
    • A61M2005/2462—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst by displacing occluding plugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
    • A61M5/286—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst
    • A61M2005/287—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst by displacing occluding plugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3106—Plugs for syringes without needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3123—Details having air entrapping or venting means, e.g. purging channels in pistons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3128—Incorporating one-way valves, e.g. pressure-relief or non-return valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M2005/3132—Syringe barrels having flow passages for injection agents at the distal end of the barrel to bypass a sealing stopper after its displacement to this end due to internal pressure increase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053—Media being expelled from injector by pressurised fluid or vacuum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
    • A61M5/2459—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst

Abstract

A cartridge and nozzle assembly for use in a non-needle injection system is provided. The assembly includes a cartridge (12) having a plunger (24) disposed at a rearward end thereof including a throat (21) at a forward portion thereof with a displaceable outlet valve (46) initially disposed within the throat (21), the outlet valve (46) being formed of resilient material, having at least one axial channel (56, 62) defined in the forward, and rearward portion thereof, between which is disposed a non-channel valve body (58); a nozzle (14) for receiving the cartridge (12); the nozzle (14) defining a rearward cartridge receiving portion, and including a forward portion terminating in, and defining a valve abutment surface (48) with an injection orifice (52) defined therein; and a recessed portion (50), the recessed portion (50) being configured to receive the valve (46) when the valve (46) is displaced to a forwardly disposed position such that the valve (46) is disposed against the valve abutment surface (48) so that the inner portion of the cartridge (12) has fluid access to the orifice (52) via the axial channels (56, 62), and around the valve body (46); a seal (22) disposed between the cartridge (12), and the nozzle (14) adjacent the forward portions thereof for at least reducing leakage of injection therebetween.
CA002353948A 1998-12-08 1999-12-03 Needleless syringe with prefilled cartridge Expired - Fee Related CA2353948C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/207,398 1998-12-08
US09/207,398 US6132395A (en) 1998-12-08 1998-12-08 Needleless syringe with prefilled cartridge
PCT/US1999/028734 WO2000033899A1 (en) 1998-12-08 1999-12-03 Needleless syringe with prefilled cartridge

Publications (2)

Publication Number Publication Date
CA2353948A1 true CA2353948A1 (en) 2000-06-15
CA2353948C CA2353948C (en) 2008-05-20

Family

ID=22770391

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002353948A Expired - Fee Related CA2353948C (en) 1998-12-08 1999-12-03 Needleless syringe with prefilled cartridge

Country Status (5)

Country Link
US (1) US6132395A (en)
JP (1) JP4226787B2 (en)
BR (1) BR9916012A (en)
CA (1) CA2353948C (en)
WO (1) WO2000033899A1 (en)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5730723A (en) 1995-10-10 1998-03-24 Visionary Medical Products Corporation, Inc. Gas pressured needle-less injection device and method
US6264629B1 (en) * 1998-11-18 2001-07-24 Bioject, Inc. Single-use needle-less hypodermic jet injection apparatus and method
US6783509B1 (en) 1998-11-18 2004-08-31 Bioject Inc. Single-use needle-less hypodermic jet injection apparatus and method
US6406455B1 (en) * 1998-12-18 2002-06-18 Biovalve Technologies, Inc. Injection devices
US7060048B1 (en) * 1999-04-16 2006-06-13 Powerject Research Limited Needleless syringe
US7074210B2 (en) * 1999-10-11 2006-07-11 Felton International, Inc. Universal protector cap with auto-disable features for needle-free injectors
US7887506B1 (en) * 1999-11-23 2011-02-15 Pulse Needlefree Systems, Inc. Safety mechanism to prevent accidental patient injection and methods of same
WO2001051109A1 (en) * 2000-01-07 2001-07-19 Biovalve Technologies, Inc. Injection device
AU2001247721A1 (en) * 2000-03-23 2001-10-03 Antares Pharma, Inc. Single use disposable jet injector
FR2809626B1 (en) * 2000-05-30 2003-03-07 Poudres & Explosifs Ste Nale NEEDLELESS SYRINGE WITH MULTI-DUCT EJECTOR INSULATION MEMBRANE
DE10034270A1 (en) * 2000-07-14 2002-02-14 Disetronic Licensing Ag Storage container with a metering device for the metered delivery of an injectable product to an injection device
EP1339442A4 (en) 2000-11-30 2006-12-27 Biovalve Technologies Inc Injection systems
GB0100756D0 (en) 2001-01-11 2001-02-21 Powderject Res Ltd Needleless syringe
US6471669B2 (en) 2001-03-05 2002-10-29 Bioject Medical Technologies Inc. Disposable needle-free injection apparatus and method
US6645170B2 (en) * 2001-03-05 2003-11-11 Bioject Medical Technologies, Inc. Simplified disposable needle-free injection apparatus and method
CA2440983A1 (en) 2001-03-14 2002-09-26 Penjet Corporation System and method for removing dissolved gas from a solution
US6613010B2 (en) 2001-04-13 2003-09-02 Penjet Corporation Modular gas-pressured needle-less injector
EP1252906A1 (en) * 2001-04-26 2002-10-30 Fada Italia, S.P.A. Improved disposable pre-filled syringe
WO2002087663A2 (en) 2001-04-27 2002-11-07 Penjet Corporation Method and apparatus for filling or refilling a needle-less injector
DE10137962A1 (en) * 2001-08-07 2003-02-20 Roesch Ag Medizintechnik Ampule for injection device for injecting medium into human or animal tissues without needle, comprising plug which closes chamber with injection medium, and is penetrated by hollow needle
US6824526B2 (en) 2001-10-22 2004-11-30 Penjet Corporation Engine and diffuser for use with a needle-less injector
US6607510B2 (en) 2001-11-09 2003-08-19 Bioject Medical Technologies Inc. Disposable needle-free injection apparatus and method
EP1476210B1 (en) 2002-02-11 2008-09-24 Antares Pharma, Inc. Intradermal injector
AU2003217404A1 (en) * 2002-02-15 2003-09-09 Antares Pharma, Inc. Injector with bypass channel
US7238167B2 (en) * 2002-06-04 2007-07-03 Bioject Inc. Needle-free injection system
US6676630B2 (en) 2002-06-04 2004-01-13 Bioject Medical Technologies, Inc. Needle-free injection system
US7156823B2 (en) * 2002-06-04 2007-01-02 Bioject Inc. High workload needle-free injection system
CN1723053A (en) * 2002-09-12 2006-01-18 儿童医院医疗中心 Method and device for painless injection of medication
US6883222B2 (en) * 2002-10-16 2005-04-26 Bioject Inc. Drug cartridge assembly and method of manufacture
US6935384B2 (en) * 2003-02-19 2005-08-30 Bioject Inc. Needle-free injection system
FR2853837B1 (en) * 2003-04-16 2006-01-13 Crossject DEVICE FOR CONNECTING AN ACTIVE PRINCIPLE RESERVOIR TO AN INJECTION NOZZLE IN A DEVICE FOR INJECTING SAID ACTIVE PRINCIPLE
BRPI0414321B8 (en) 2003-09-22 2021-06-22 Baxter Healthcare Sa high pressure sterilization for final sterilization of pharmaceutical preparations and medical products
US7670314B2 (en) * 2004-02-17 2010-03-02 Children's Hospital Medical Center Injection device for administering a vaccine
US7717874B2 (en) * 2004-05-28 2010-05-18 Bioject, Inc. Needle-free injection system
EP2532378B1 (en) 2004-12-01 2016-04-27 AcuShot, Inc. Needle-free injector
DE102004059126B4 (en) * 2004-12-08 2014-01-16 Roche Diagnostics Gmbh Adapter for injection device
US8262605B2 (en) * 2004-12-09 2012-09-11 Ams Research Corporation Needleless delivery systems
JP5216328B2 (en) 2005-01-24 2013-06-19 アンタレス ファーマ インコーポレイテッド Pre-filled needle assist syringe jet injector
US8998881B2 (en) 2005-08-10 2015-04-07 Alza Corporation Method for delivering drugs to tissue under microjet propulsion
US20090312696A1 (en) * 2005-12-28 2009-12-17 Copa Vincent G Devices, Systems, and Related Methods for Delivery of Fluid to Tissue
RU2008129182A (en) * 2006-01-31 2010-03-10 Ново Нордиск А/С (DK) INSULATING COMPONENT FOR PRE-FILLED MEDICAL JET INJECTOR
US8251947B2 (en) 2006-05-03 2012-08-28 Antares Pharma, Inc. Two-stage reconstituting injector
US9233206B2 (en) * 2006-08-30 2016-01-12 Arthur Harris Continuous feed hypodermic syringe with self contained cartridge dispenser
FR2905872B1 (en) * 2006-09-19 2008-12-19 Crossjet NEEDLE-FREE INJECTION DEVICE WITH SECURE TANK
US7942845B2 (en) * 2006-09-19 2011-05-17 Bioject, Inc. Needle-free injector and process for providing serial injections
US7547293B2 (en) 2006-10-06 2009-06-16 Bioject, Inc. Triggering mechanism for needle-free injector
US20080119823A1 (en) * 2006-11-21 2008-05-22 Crank Justin M Injection Tube for Jet Injection Device
US8382713B2 (en) * 2006-12-11 2013-02-26 Kenergy Scientific, Inc. Drug delivery device and methodology
WO2008103997A2 (en) 2007-02-23 2008-08-28 Bioject Inc. Needle-free injection devices and drug delivery systems therefor
GB0708758D0 (en) 2007-05-04 2007-06-13 Powderject Res Ltd Particle cassettes and process thereof
US20090137949A1 (en) * 2007-11-26 2009-05-28 Bioject Inc. Needle-free injection device with nozzle auto-disable
US8617099B2 (en) * 2007-11-26 2013-12-31 Bioject Inc. Injection device plunger auto-disable
JP5313236B2 (en) * 2008-04-10 2013-10-09 パナソニック株式会社 Drug administration device
JP5611208B2 (en) 2008-08-05 2014-10-22 アンタレス・ファーマ・インコーポレーテッド Multiple dose injection device
JP4439577B1 (en) * 2008-11-28 2010-03-24 株式会社アルテ Container / Syringe
WO2010108116A1 (en) 2009-03-20 2010-09-23 Antares Pharma, Inc. Hazardous agent injection system
JP2013535282A (en) * 2010-08-06 2013-09-12 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Method and system for holding a cartridge in a holder
EP2600922B2 (en) * 2010-08-06 2022-07-20 Sanofi-Aventis Deutschland GmbH Cartridge holder and method for assembling a cartridge unit for a drug delivery device
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
EP3400982B1 (en) * 2011-07-19 2021-06-16 Sanofi-Aventis Deutschland GmbH Cartridge holder for a drug delivery device
KR20150011346A (en) 2012-04-06 2015-01-30 안타레스 팔마, 인코퍼레이티드 Needle assisted jet injection administration of testosterone compositions
US9364610B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Injection device with cammed ram assembly
EP4349383A2 (en) 2013-02-11 2024-04-10 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
EP2968792B1 (en) 2013-03-11 2019-05-15 Antares Pharma, Inc. Dosage injector with pinion system
FR3058718B1 (en) * 2016-11-15 2020-11-06 Crossject AIR TEMPERING PROCESS OF AN ELONGATED HOLLOW GLASS BODY INCLUDING AN AXIAL DRILLING
US20200360611A1 (en) * 2017-11-10 2020-11-19 Cc - Pharma Gmbh Method and device for the needle-free injecting of fluid into a substrate, and fluid container for use in the method and the device
EP3632817A1 (en) 2018-10-02 2020-04-08 Sulzer Mixpac AG Cartridge, method of making a cartridge and method of using a cartridge
US20220401651A1 (en) * 2019-11-19 2022-12-22 Eli Lilly And Company Drug delivery systems including displaceable closures

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3941128A (en) * 1970-11-10 1976-03-02 Affiliated Hospital Products, Inc. Fluid dispensing arrangement
US3729031A (en) * 1971-12-06 1973-04-24 Mpl Inc Liquid dispenser and plunger and method and apparatus for filling same
US3940003A (en) * 1974-05-07 1976-02-24 Pharmaco, Inc. Safety cap for medicament vial having puncturable seal
US4592745A (en) * 1984-02-29 1986-06-03 Novo Industri A/S Dispenser
US4662878A (en) * 1985-11-13 1987-05-05 Patents Unlimited Ltd. Medicine vial adaptor for needleless injector
EP0250022A3 (en) * 1986-06-17 1988-06-22 SICIM SpA Portable endermic injector
US4713061A (en) * 1986-07-14 1987-12-15 Survival Technology, Inc. Cartridge with universal plastic hub
US4747839A (en) * 1986-12-17 1988-05-31 Survival Technology, Inc. Disposable hypodermic syringe with plastic snap-on needle hub and heat shrink seal therefor
US4886495A (en) * 1987-07-08 1989-12-12 Duoject Medical Systems Inc. Vial-based prefilled syringe system for one or two component medicaments
US4790824A (en) * 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US4940460A (en) * 1987-06-19 1990-07-10 Bioject, Inc. Patient-fillable and non-invasive hypodermic injection device assembly
US4941880A (en) * 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
AU595096B2 (en) * 1988-02-10 1990-03-22 Astra Pharmaceuticals Pty Ltd Plastic cartridge and syringe
US4909794A (en) * 1988-06-24 1990-03-20 Habley Medical Technology Corporation Combination retractable needle cannula and cannula lock for a medication carpule
US5024656A (en) * 1988-08-30 1991-06-18 Injet Medical Products, Inc. Gas-pressure-regulated needleless injection system
US5049128A (en) * 1990-02-06 1991-09-17 Duquette Irene A Valved infusion port
EP0518416A1 (en) * 1991-06-13 1992-12-16 Duphar International Research B.V Injection device
DK134691D0 (en) * 1991-07-12 1991-07-12 Novo Nordisk As APPARATUS
GB9212742D0 (en) * 1992-06-16 1992-07-29 Sterimatic Holdings Ltd Syringe or blood collection system
US5383851A (en) * 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
US5405333A (en) * 1992-12-28 1995-04-11 Richmond; Frank M. Liquid medicament bag with needleless connector fitting using boat assembly
US5364386A (en) * 1993-05-05 1994-11-15 Hikari Seiyaku Kabushiki Kaisha Infusion unit
US5472022A (en) * 1993-11-02 1995-12-05 Genentech, Inc. Injection pen solution transfer apparatus and method
US5716348A (en) * 1995-10-19 1998-02-10 Meridian Medical Technologies, Inc. Anti-coring needle
GB9607549D0 (en) * 1996-04-11 1996-06-12 Weston Medical Ltd Spring-powered dispensing device

Also Published As

Publication number Publication date
CA2353948C (en) 2008-05-20
WO2000033899A1 (en) 2000-06-15
JP4226787B2 (en) 2009-02-18
JP2002531227A (en) 2002-09-24
BR9916012A (en) 2002-07-09
US6132395A (en) 2000-10-17

Similar Documents

Publication Publication Date Title
CA2353948A1 (en) Needleless syringe with prefilled cartridge
US4842591A (en) Connector with one-way septum valve, and assembly
EP0588148B1 (en) Syringe having needle isolation features
US5273533A (en) Medical valve
CN101637627B (en) Auto-disable device for syringes
US7488308B2 (en) Injector with bypass channel
EP0737484A3 (en) Prefilled syringe for injection of two liquids
US5935101A (en) Two-compartment type prefilled syringe
EP0695554B1 (en) Automatic injector
WO1996010430A3 (en) Improved dual-chamber syringe & methods
US6602223B2 (en) Elastic and sliding valvular joint, suitable to work in pre-filled syringes
WO2001093787A3 (en) High pressure injection syringe
JP3167452U (en) Syringe
CA2248483C (en) Adaptor system for syringe pre-filled with liquid medicament and syringe pre-filled with liquid medicament
ATE515283T1 (en) NEEDLELESS SUBCUTANEOUS JET INJECTION DEVICE
CN104349813A (en) Male medical implement cleaning device
WO2002074381A3 (en) Implantable refillable and rate controlled drug delivery device
WO1998039594A1 (en) Control of fluid flow
EP1192966B1 (en) Injector with a force sensor on the plunger
JP3328781B2 (en) Syringe
US5613951A (en) Single use injection device
JPH056995Y2 (en)
CA2044223A1 (en) Flexible sealing member for injection device
KR20190085318A (en) Needleless Connector And Method Of Manufacturing The Needleless Connector's Septum
AU3557095A (en) Injection means

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20141203