CA2339846A1 - Methods and apparatus for intraluminal deposition of hydrogels - Google Patents

Methods and apparatus for intraluminal deposition of hydrogels Download PDF

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Publication number
CA2339846A1
CA2339846A1 CA002339846A CA2339846A CA2339846A1 CA 2339846 A1 CA2339846 A1 CA 2339846A1 CA 002339846 A CA002339846 A CA 002339846A CA 2339846 A CA2339846 A CA 2339846A CA 2339846 A1 CA2339846 A1 CA 2339846A1
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Prior art keywords
methods
hydrogels
delivery system
hydrogel systems
intraluminal
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Granted
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CA002339846A
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French (fr)
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CA2339846C (en
Inventor
Amarpreet S. Sawhney
John Spiridigliozzi
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Incept Llc
Amarpreet S. Sawhney
John Spiridigliozzi
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Publication of CA2339846A1 publication Critical patent/CA2339846A1/en
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    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/20Vas deferens occluders; Fallopian occluders
    • A61F6/22Vas deferens occluders; Fallopian occluders implantable in tubes
    • A61F6/225Vas deferens occluders; Fallopian occluders implantable in tubes transcervical
    • AHUMAN NECESSITIES
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    • A61B17/12186Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices liquid materials adapted to be injected
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    • A61K9/0012Galenical forms characterised by the site of application
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    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
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    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001Use of materials characterised by their function or physical properties
    • A61L24/0031Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
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    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/146Porous materials, e.g. foams or sponges
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    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M25/10Balloon catheters
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
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Abstract

Methods and apparatus of forming hydrogel systems in situ are provided using a delivery system (10) configured to deliver two or more fluent pre-polymer solutions without premature cross-linking. The delivery system (10) comprises separate first and second lumens (23, 24) coupling first, and second inlet ports (14, 15), first and second outlet ports (16, 17), respectively, and may include a balloon, flexible distal region, mixing chamber or steerable distal end. Multi-component hydrogel systems suitable for use with the inventive methods, and apparatus are also described.
CA002339846A 1998-08-14 1999-08-13 Methods and apparatus for intraluminal deposition of hydrogels Expired - Lifetime CA2339846C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/133,950 1998-08-14
US09/133,950 US6152943A (en) 1998-08-14 1998-08-14 Methods and apparatus for intraluminal deposition of hydrogels
PCT/US1999/018521 WO2000009190A1 (en) 1998-08-14 1999-08-13 Methods and apparatus for intraluminal deposition of hydrogels

Publications (2)

Publication Number Publication Date
CA2339846A1 true CA2339846A1 (en) 2000-02-24
CA2339846C CA2339846C (en) 2009-10-20

Family

ID=22461057

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002339846A Expired - Lifetime CA2339846C (en) 1998-08-14 1999-08-13 Methods and apparatus for intraluminal deposition of hydrogels

Country Status (9)

Country Link
US (6) US6152943A (en)
EP (1) EP1105180B1 (en)
JP (1) JP4262891B2 (en)
AT (1) ATE428463T1 (en)
AU (1) AU5562399A (en)
CA (1) CA2339846C (en)
DE (1) DE69940741D1 (en)
ES (1) ES2325103T3 (en)
WO (1) WO2000009190A1 (en)

Families Citing this family (559)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6248110B1 (en) * 1994-01-26 2001-06-19 Kyphon, Inc. Systems and methods for treating fractured or diseased bone using expandable bodies
US20030032963A1 (en) * 2001-10-24 2003-02-13 Kyphon Inc. Devices and methods using an expandable body with internal restraint for compressing cancellous bone
US6302875B1 (en) 1996-10-11 2001-10-16 Transvascular, Inc. Catheters and related devices for forming passageways between blood vessels or other anatomical structures
US20090324721A1 (en) 1996-09-23 2009-12-31 Jack Kennedy Hydrogels Suitable For Use In Polyp Removal
US6743248B2 (en) 1996-12-18 2004-06-01 Neomend, Inc. Pretreatment method for enhancing tissue adhesion
CN1626048B (en) 1997-01-24 2012-09-12 帕拉贡知识产权有限责任公司 Expandable device having bistable spring construction
US8353948B2 (en) * 1997-01-24 2013-01-15 Celonova Stent, Inc. Fracture-resistant helical stent incorporating bistable cells and methods of use
US6371975B2 (en) 1998-11-06 2002-04-16 Neomend, Inc. Compositions, systems, and methods for creating in situ, chemically cross-linked, mechanical barriers
US20030191496A1 (en) 1997-03-12 2003-10-09 Neomend, Inc. Vascular sealing device with microwave antenna
US6540712B1 (en) * 1998-03-13 2003-04-01 Arteria Medical Science, Inc. Methods and low profile apparatus for reducing embolization during treatment of carotid artery disease
US20050131453A1 (en) * 1998-03-13 2005-06-16 Parodi Juan C. Apparatus and methods for reducing embolization during treatment of carotid artery disease
US6908474B2 (en) * 1998-05-13 2005-06-21 Gore Enterprise Holdings, Inc. Apparatus and methods for reducing embolization during treatment of carotid artery disease
US6719773B1 (en) * 1998-06-01 2004-04-13 Kyphon Inc. Expandable structures for deployment in interior body regions
DE69942858D1 (en) * 1998-06-01 2010-11-25 Kyphon S A R L DEFINABLE, PREFORMED STRUCTURES FOR ESTABLISHMENT IN REGIONS INSIDE THE BODY
US7335220B2 (en) * 2004-11-05 2008-02-26 Access Closure, Inc. Apparatus and methods for sealing a vascular puncture
US6703047B2 (en) * 2001-02-02 2004-03-09 Incept Llc Dehydrated hydrogel precursor-based, tissue adherent compositions and methods of use
US6458147B1 (en) 1998-11-06 2002-10-01 Neomend, Inc. Compositions, systems, and methods for arresting or controlling bleeding or fluid leakage in body tissue
US6994686B2 (en) 1998-08-26 2006-02-07 Neomend, Inc. Systems for applying cross-linked mechanical barriers
US6899889B1 (en) 1998-11-06 2005-05-31 Neomend, Inc. Biocompatible material composition adaptable to diverse therapeutic indications
US7279001B2 (en) * 1998-11-06 2007-10-09 Neomend, Inc. Systems, methods, and compositions for achieving closure of vascular puncture sites
US6949114B2 (en) * 1998-11-06 2005-09-27 Neomend, Inc. Systems, methods, and compositions for achieving closure of vascular puncture sites
US6830756B2 (en) * 1998-11-06 2004-12-14 Neomend, Inc. Systems, methods, and compositions for achieving closure of vascular puncture sites
US20080114092A1 (en) * 1998-12-04 2008-05-15 Incept Llc Adhesion barriers applicable by minimally invasive surgery and methods of use thereof
US20020169473A1 (en) * 1999-06-02 2002-11-14 Concentric Medical, Inc. Devices and methods for treating vascular malformations
US6358197B1 (en) * 1999-08-13 2002-03-19 Enteric Medical Technologies, Inc. Apparatus for forming implants in gastrointestinal tract and kit for use therewith
US7048717B1 (en) 1999-09-27 2006-05-23 Essex Technology, Inc. Rotate-to-advance catheterization system
CA2397224A1 (en) * 2000-02-03 2001-08-09 Tissuemed Limited Device for the closure of a surgical puncture
US6652883B2 (en) 2000-03-13 2003-11-25 Biocure, Inc. Tissue bulking and coating compositions
DE60119906T2 (en) 2000-03-13 2007-01-11 Biocure, Inc. COMPOSITIONS FOR INCREASING TISSUE VOLUME AND COATING COMPOSITIONS
JP4871476B2 (en) 2000-03-13 2012-02-08 バイオコンパティブルズ ユーケー リミテッド Embolization composition
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US8088060B2 (en) 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US6663589B1 (en) 2000-06-20 2003-12-16 Haim Halevy Catheter system
EP1301245A4 (en) * 2000-07-17 2007-02-28 Haemacure Corp Spray head for applying a multi-component mixture
US6620196B1 (en) * 2000-08-30 2003-09-16 Sdgi Holdings, Inc. Intervertebral disc nucleus implants and methods
US20020147462A1 (en) * 2000-09-11 2002-10-10 Closure Medical Corporation Bronchial occlusion method and apparatus
AU9576501A (en) * 2000-10-23 2002-05-06 Tissuemed Ltd Self-adhesive hydratable matrix for topical therapeutic use
US6565601B2 (en) 2000-11-15 2003-05-20 Micro Therapeutics, Inc. Methods for vascular reconstruction of diseased arteries
JP2004527268A (en) * 2000-11-15 2004-09-09 マイクロ・セラピューティクス・インコーポレーテッド Methods for vascular reconstruction of diseased arteries
US6565530B2 (en) * 2001-02-28 2003-05-20 Scimed Life Systems, Inc. Immobilizing objects in the body
US6602269B2 (en) 2001-03-30 2003-08-05 Scimed Life Systems Embolic devices capable of in-situ reinforcement
WO2002087416A2 (en) * 2001-04-26 2002-11-07 Porter Christopher H Method and apparatus for delivering materials to the body
US20030004533A1 (en) * 2001-05-04 2003-01-02 Concentric Medical Bioactive polymer vaso-occlusive device
US6685745B2 (en) * 2001-05-15 2004-02-03 Scimed Life Systems, Inc. Delivering an agent to a patient's body
US20030014075A1 (en) * 2001-07-16 2003-01-16 Microvention, Inc. Methods, materials and apparatus for deterring or preventing endoleaks following endovascular graft implanation
WO2003020138A1 (en) * 2001-08-31 2003-03-13 Scimed Life Systems, Inc. Percutaneous pringle occlusion device
US8075558B2 (en) 2002-04-30 2011-12-13 Surgrx, Inc. Electrosurgical instrument and method
US8777969B2 (en) 2001-10-23 2014-07-15 Covidien Lp Surgical fasteners
AU2002359410A1 (en) * 2001-11-16 2003-06-10 Biocure, Inc. Methods for initiating in situ formation of hydrogels
WO2003063928A2 (en) * 2002-01-25 2003-08-07 Biocure, Inc. Coaxial delivery device
US6989024B2 (en) 2002-02-28 2006-01-24 Counter Clockwise, Inc. Guidewire loaded stent for delivery through a catheter
US7094369B2 (en) * 2002-03-29 2006-08-22 Scimed Life Systems, Inc. Processes for manufacturing polymeric microspheres
US7131997B2 (en) * 2002-03-29 2006-11-07 Scimed Life Systems, Inc. Tissue treatment
US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
US7053134B2 (en) * 2002-04-04 2006-05-30 Scimed Life Systems, Inc. Forming a chemically cross-linked particle of a desired shape and diameter
US7756583B2 (en) 2002-04-08 2010-07-13 Ardian, Inc. Methods and apparatus for intravascularly-induced neuromodulation
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US20070135875A1 (en) 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US8347891B2 (en) 2002-04-08 2013-01-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen
US20070129761A1 (en) 2002-04-08 2007-06-07 Ardian, Inc. Methods for treating heart arrhythmia
US9636174B2 (en) 2002-04-08 2017-05-02 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US7617005B2 (en) 2002-04-08 2009-11-10 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US20080213331A1 (en) 2002-04-08 2008-09-04 Ardian, Inc. Methods and devices for renal nerve blocking
US7771387B2 (en) * 2002-05-17 2010-08-10 Boston Scientific Scimed, Inc. Liquid embolic composition delivery devices and methods
ES2369640T3 (en) 2002-05-24 2011-12-02 Angiotech International Ag COMPOSITIONS AND METHODS TO COVER MEDICAL IMPLANTS.
US7338511B2 (en) * 2002-05-24 2008-03-04 Boston Scientific-Scimed, Inc. Solid embolic material with variable expansion
US20040002752A1 (en) 2002-06-26 2004-01-01 Scimed Life Systems, Inc. Sacrificial anode stent system
US7842377B2 (en) * 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US7449236B2 (en) * 2002-08-09 2008-11-11 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US8012454B2 (en) * 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US7846141B2 (en) 2002-09-03 2010-12-07 Bluesky Medical Group Incorporated Reduced pressure treatment system
AU2003272682C1 (en) 2002-09-20 2009-07-16 Nellix, Inc. Stent-graft with positioning anchor
US7883490B2 (en) * 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
US7588825B2 (en) * 2002-10-23 2009-09-15 Boston Scientific Scimed, Inc. Embolic compositions
AU2003303289A1 (en) * 2002-10-23 2004-09-28 Biomerix Corporation. Aneurysm treatment devices and methods
US10363061B2 (en) 2002-10-25 2019-07-30 Hydrocision, Inc. Nozzle assemblies for liquid jet surgical instruments and surgical instruments for employing the nozzle assemblies
GB0224986D0 (en) 2002-10-28 2002-12-04 Smith & Nephew Apparatus
AU2003279823A1 (en) 2002-10-28 2004-05-25 Northgate Technologies Inc. Dual-capacity insufflator tube
US8187324B2 (en) * 2002-11-15 2012-05-29 Advanced Cardiovascular Systems, Inc. Telescoping apparatus for delivering and adjusting a medical device in a vessel
US9149602B2 (en) 2005-04-22 2015-10-06 Advanced Cardiovascular Systems, Inc. Dual needle delivery system
US20040158112A1 (en) * 2003-02-10 2004-08-12 Conocophillips Company Silicon carbide-supported catalysts for oxidative dehydrogenation of hydrocarbons
JP2006520786A (en) * 2003-03-14 2006-09-14 シネクサス, インコーポレイテッド Sinus delivery of sustained-release therapeutic agents
WO2004087007A2 (en) * 2003-03-25 2004-10-14 Biocure, Inc. Hydrogel string medical device
JP2006523113A (en) * 2003-04-04 2006-10-12 ティシュームド リミテッド Tissue adhesive composition
US7273896B2 (en) 2003-04-10 2007-09-25 Angiotech Pharmaceuticals (Us), Inc. Compositions and methods of using a transient colorant
US8048407B2 (en) * 2003-04-24 2011-11-01 Brent Vernon In situ gelling self-reactive materials for embolization
US7654975B2 (en) * 2003-04-24 2010-02-02 Northgate Technologies, Inc. Mixed-gas insufflation system
US7387645B2 (en) * 2003-04-25 2008-06-17 Medtronic Vascular, Inc. Cellular therapy to heal vascular tissue
US7025768B2 (en) * 2003-05-06 2006-04-11 Boston Scientific Scimed, Inc. Systems and methods for ablation of tissue
AU2004241111B2 (en) 2003-05-15 2010-05-27 Dsm Ip Assets B.V Manufacture and use of implantable reticulated elastomeric matrices
US20040230289A1 (en) 2003-05-15 2004-11-18 Scimed Life Systems, Inc. Sealable attachment of endovascular stent to graft
US20040236410A1 (en) * 2003-05-22 2004-11-25 Atrium Medical Corp. Polymeric body formation
US9289195B2 (en) 2003-06-04 2016-03-22 Access Closure, Inc. Auto-retraction apparatus and methods for sealing a vascular puncture
US7331979B2 (en) * 2003-06-04 2008-02-19 Access Closure, Inc. Apparatus and methods for sealing a vascular puncture
US8393328B2 (en) 2003-08-22 2013-03-12 BiO2 Medical, Inc. Airway assembly and methods of using an airway assembly
US7976823B2 (en) 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
EP2452648B1 (en) 2003-09-12 2016-02-10 Vessix Vascular, Inc. System for selectable eccentric remodeling and/or ablation of atherosclerotic material
EP1673125B1 (en) 2003-10-07 2009-12-23 Northgate Technologies Incorporated System for delivering a substance to a body cavity
US20050090804A1 (en) * 2003-10-22 2005-04-28 Trivascular, Inc. Endoluminal prosthesis endoleak management
US7914517B2 (en) * 2003-10-31 2011-03-29 Trudell Medical International System and method for manipulating a catheter for delivering a substance to a body cavity
US7901770B2 (en) 2003-11-04 2011-03-08 Boston Scientific Scimed, Inc. Embolic compositions
US20050107867A1 (en) * 2003-11-17 2005-05-19 Taheri Syde A. Temporary absorbable venous occlusive stent and superficial vein treatment method
US20050208095A1 (en) * 2003-11-20 2005-09-22 Angiotech International Ag Polymer compositions and methods for their use
US20070060950A1 (en) 2003-12-24 2007-03-15 Farhad Khosravi Apparatus and methods for delivering sealing materials during a percutaneous procedure to facilitate hemostasis
US7763077B2 (en) 2003-12-24 2010-07-27 Biomerix Corporation Repair of spinal annular defects and annulo-nucleoplasty regeneration
US20050245876A1 (en) * 2003-12-24 2005-11-03 Accessclosure, Inc. Apparatus and methods for facilitating access through a puncture including sealing compound therein
JP2007517614A (en) * 2004-01-07 2007-07-05 ボストン サイエンティフィック サンタ ローザ コーポレイション Method for occluding a body lumen, occlusive composition and device
US9238127B2 (en) 2004-02-25 2016-01-19 Femasys Inc. Methods and devices for delivering to conduit
US8052669B2 (en) 2004-02-25 2011-11-08 Femasys Inc. Methods and devices for delivery of compositions to conduits
US8048101B2 (en) 2004-02-25 2011-11-01 Femasys Inc. Methods and devices for conduit occlusion
US8048086B2 (en) 2004-02-25 2011-11-01 Femasys Inc. Methods and devices for conduit occlusion
US7736671B2 (en) * 2004-03-02 2010-06-15 Boston Scientific Scimed, Inc. Embolization
US20050220882A1 (en) * 2004-03-04 2005-10-06 Wilson Pritchard Materials for medical implants and occlusive devices
US20050228433A1 (en) * 2004-03-16 2005-10-13 Weenna Bucay-Couto In situ implant and method of forming same
WO2005092204A2 (en) 2004-03-22 2005-10-06 Accessclosure, Inc. Apparatus for sealing a vascular puncture
US8173176B2 (en) 2004-03-30 2012-05-08 Boston Scientific Scimed, Inc. Embolization
US7909805B2 (en) 2004-04-05 2011-03-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US8062272B2 (en) 2004-05-21 2011-11-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US10058642B2 (en) 2004-04-05 2018-08-28 Bluesky Medical Group Incorporated Reduced pressure treatment system
US20050226991A1 (en) * 2004-04-07 2005-10-13 Hossainy Syed F Methods for modifying balloon of a catheter assembly
US9554691B2 (en) 2004-04-21 2017-01-31 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US10188413B1 (en) 2004-04-21 2019-01-29 Acclarent, Inc. Deflectable guide catheters and related methods
US7462175B2 (en) 2004-04-21 2008-12-09 Acclarent, Inc. Devices, systems and methods for treating disorders of the ear, nose and throat
US7419497B2 (en) 2004-04-21 2008-09-02 Acclarent, Inc. Methods for treating ethmoid disease
US20070208252A1 (en) 2004-04-21 2007-09-06 Acclarent, Inc. Systems and methods for performing image guided procedures within the ear, nose, throat and paranasal sinuses
US7559925B2 (en) 2006-09-15 2009-07-14 Acclarent Inc. Methods and devices for facilitating visualization in a surgical environment
US7803150B2 (en) 2004-04-21 2010-09-28 Acclarent, Inc. Devices, systems and methods useable for treating sinusitis
US20070167682A1 (en) 2004-04-21 2007-07-19 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US9101384B2 (en) 2004-04-21 2015-08-11 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, Nose and/or throat
US8702626B1 (en) 2004-04-21 2014-04-22 Acclarent, Inc. Guidewires for performing image guided procedures
US8932276B1 (en) 2004-04-21 2015-01-13 Acclarent, Inc. Shapeable guide catheters and related methods
US8894614B2 (en) 2004-04-21 2014-11-25 Acclarent, Inc. Devices, systems and methods useable for treating frontal sinusitis
US20190314620A1 (en) 2004-04-21 2019-10-17 Acclarent, Inc. Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures
US20060063973A1 (en) 2004-04-21 2006-03-23 Acclarent, Inc. Methods and apparatus for treating disorders of the ear, nose and throat
US7654997B2 (en) 2004-04-21 2010-02-02 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat
US9351750B2 (en) 2004-04-21 2016-05-31 Acclarent, Inc. Devices and methods for treating maxillary sinus disease
US9399121B2 (en) 2004-04-21 2016-07-26 Acclarent, Inc. Systems and methods for transnasal dilation of passageways in the ear, nose or throat
US8764729B2 (en) 2004-04-21 2014-07-01 Acclarent, Inc. Frontal sinus spacer
US9089258B2 (en) 2004-04-21 2015-07-28 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US8864787B2 (en) 2004-04-21 2014-10-21 Acclarent, Inc. Ethmoidotomy system and implantable spacer devices having therapeutic substance delivery capability for treatment of paranasal sinusitis
US8747389B2 (en) 2004-04-21 2014-06-10 Acclarent, Inc. Systems for treating disorders of the ear, nose and throat
US20050238870A1 (en) * 2004-04-22 2005-10-27 Marcia Buiser Embolization
GB0409446D0 (en) 2004-04-28 2004-06-02 Smith & Nephew Apparatus
US7311861B2 (en) 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
US7670282B2 (en) * 2004-06-14 2010-03-02 Pneumrx, Inc. Lung access device
US20060004400A1 (en) 2004-06-16 2006-01-05 Mcgurk Erin Method of treating a lung
US7766891B2 (en) * 2004-07-08 2010-08-03 Pneumrx, Inc. Lung device with sealing features
US7766938B2 (en) * 2004-07-08 2010-08-03 Pneumrx, Inc. Pleural effusion treatment device, method and material
WO2006014568A2 (en) * 2004-07-08 2006-02-09 Pneumrx, Inc. Lung device with sealing features
US8048145B2 (en) 2004-07-22 2011-11-01 Endologix, Inc. Graft systems having filling structures supported by scaffolds and methods for their use
CA2575943A1 (en) * 2004-08-03 2006-02-09 Tissuemed Limited Tissue-adhesive materials
US20060045900A1 (en) * 2004-08-27 2006-03-02 Robert Richard Embolization
US8348971B2 (en) 2004-08-27 2013-01-08 Accessclosure, Inc. Apparatus and methods for facilitating hemostasis within a vascular puncture
WO2006026412A2 (en) * 2004-08-31 2006-03-09 Vnus Medical Technologies, Inc. Apparatus and material composition for permanent occlusion of a hollow anatomical structure
US8396548B2 (en) 2008-11-14 2013-03-12 Vessix Vascular, Inc. Selective drug delivery in a lumen
US9713730B2 (en) 2004-09-10 2017-07-25 Boston Scientific Scimed, Inc. Apparatus and method for treatment of in-stent restenosis
US7909809B2 (en) 2004-09-27 2011-03-22 Boston Scientific Scimed, Inc. Devices and methods for agent-assisted medical procedures
US7938307B2 (en) 2004-10-18 2011-05-10 Tyco Healthcare Group Lp Support structures and methods of using the same
US7845536B2 (en) 2004-10-18 2010-12-07 Tyco Healthcare Group Lp Annular adhesive structure
US8262693B2 (en) 2004-11-05 2012-09-11 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
US7201918B2 (en) * 2004-11-16 2007-04-10 Microvention, Inc. Compositions, systems and methods for treatment of defects in blood vessels
CA2587857C (en) * 2004-11-23 2017-10-10 Pneumrx, Inc. Steerable device for accessing a target site and methods
CA2588726A1 (en) * 2004-11-26 2006-06-01 The Regents Of The University Of California Devices, systems and methods for controlling local blood pressure
US8425550B2 (en) 2004-12-01 2013-04-23 Boston Scientific Scimed, Inc. Embolic coils
WO2006063199A2 (en) 2004-12-09 2006-06-15 The Foundry, Inc. Aortic valve repair
ES2625531T3 (en) * 2005-01-18 2017-07-19 Acclarent, Inc. Paranasal insertion device
CN101146484B (en) * 2005-01-25 2015-04-08 泰科医疗集团有限合伙公司 Structures for permanent occlusion of a hollow anatomical structure
US20060178696A1 (en) * 2005-02-04 2006-08-10 Porter Stephen C Macroporous materials for use in aneurysms
US7611494B2 (en) * 2005-02-08 2009-11-03 Confluent Surgical, Inc. Spray for fluent materials
EP1846505B1 (en) 2005-02-09 2015-11-11 Covidien LP Synthetic sealants
US7907991B2 (en) * 2005-03-02 2011-03-15 C. R. Bard, Inc. System and method for marking body cavities
US7727555B2 (en) * 2005-03-02 2010-06-01 Boston Scientific Scimed, Inc. Particles
US7858183B2 (en) * 2005-03-02 2010-12-28 Boston Scientific Scimed, Inc. Particles
US20060276859A1 (en) * 2005-06-02 2006-12-07 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Photopatterning of skin
US8157807B2 (en) * 2005-06-02 2012-04-17 The Invention Science Fund I, Llc Skin treatment including patterned light
US9364229B2 (en) 2005-03-15 2016-06-14 Covidien Lp Circular anastomosis structures
US7931029B2 (en) * 2005-03-25 2011-04-26 Boston Scientific Scimed, Inc. Method and apparatus for uterus stabilization
US20060222596A1 (en) 2005-04-01 2006-10-05 Trivascular, Inc. Non-degradable, low swelling, water soluble radiopaque hydrogel polymer
US20060229492A1 (en) * 2005-04-08 2006-10-12 G & L Consulting Llc Materials and methods for in situ formation of a heart constrainer
US8002742B2 (en) * 2005-04-22 2011-08-23 Accessclosure, Inc. Apparatus and methods for sealing a puncture in tissue
US7806856B2 (en) * 2005-04-22 2010-10-05 Accessclosure, Inc. Apparatus and method for temporary hemostasis
EP3199110A1 (en) 2005-04-22 2017-08-02 Access Closure, Inc. Apparatus and method for sealing a puncture in tissue
US7963287B2 (en) * 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
DE102005024625B3 (en) * 2005-05-30 2007-02-08 Siemens Ag Stent for positioning in a body tube
US20070032846A1 (en) * 2005-08-05 2007-02-08 Bran Ferren Holographic tattoo
US8951225B2 (en) 2005-06-10 2015-02-10 Acclarent, Inc. Catheters with non-removable guide members useable for treatment of sinusitis
US20070004973A1 (en) * 2005-06-15 2007-01-04 Tan Sharon M L Tissue treatment methods
US9463426B2 (en) * 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
US20070038270A1 (en) * 2005-07-05 2007-02-15 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Multi step photopatterning of skin
EP1903985A4 (en) 2005-07-07 2010-04-28 Nellix Inc Systems and methods for endovascular aneurysm treatment
US20070032777A1 (en) * 2005-07-21 2007-02-08 Perkins James T Concentric thin wall surgical irrigation tubing
US8702789B2 (en) 2005-07-29 2014-04-22 Cvdevices, Llc Endoprosthesis assemblies and methods for using the same
US9050091B2 (en) * 2005-07-29 2015-06-09 Cvdevices, Llc Endograft devices and methods for using the same
US20070048340A1 (en) * 2005-08-31 2007-03-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Multi step patterning of a skin surface
CA2621657C (en) * 2005-09-21 2014-06-17 Surmodics, Inc. In situ occluding compositions comprising natural biodegradable polysaccharides polymerized by a redox pair
US8007509B2 (en) 2005-10-12 2011-08-30 Boston Scientific Scimed, Inc. Coil assemblies, components and methods
US9101742B2 (en) * 2005-10-28 2015-08-11 Baxter International Inc. Gastrointestinal applicator and method of using same
US8101197B2 (en) 2005-12-19 2012-01-24 Stryker Corporation Forming coils
US8152839B2 (en) 2005-12-19 2012-04-10 Boston Scientific Scimed, Inc. Embolic coils
US7501179B2 (en) * 2005-12-21 2009-03-10 Boston Scientific Scimed, Inc. Block copolymer particles
US20070142560A1 (en) * 2005-12-21 2007-06-21 Young-Ho Song Block copolymer particles
US7947368B2 (en) 2005-12-21 2011-05-24 Boston Scientific Scimed, Inc. Block copolymer particles
US9427216B2 (en) * 2005-12-23 2016-08-30 CARDINAL HEALTH SWITZERLAND 515 GmbH Systems and methods for closing a vessel wound
US20070208213A1 (en) * 2006-02-03 2007-09-06 Swann Susan E Method and apparatus for in-vitro fertilization and tubal occlusion
EP1979018B1 (en) 2006-02-03 2013-08-07 Tissuemed Limited Tissue-adhesive materials
US8062282B2 (en) * 2006-02-13 2011-11-22 Fossa Medical, Inc. Methods and apparatus for temporarily occluding body openings
US20090018575A1 (en) * 2006-03-01 2009-01-15 Tissuemed Limited Tissue-adhesive formulations
US8157837B2 (en) 2006-03-13 2012-04-17 Pneumrx, Inc. Minimally invasive lung volume reduction device and method
US9402633B2 (en) 2006-03-13 2016-08-02 Pneumrx, Inc. Torque alleviating intra-airway lung volume reduction compressive implant structures
US8888800B2 (en) 2006-03-13 2014-11-18 Pneumrx, Inc. Lung volume reduction devices, methods, and systems
US8795709B2 (en) 2006-03-29 2014-08-05 Incept Llc Superabsorbent, freeze dried hydrogels for medical applications
US9017361B2 (en) * 2006-04-20 2015-04-28 Covidien Lp Occlusive implant and methods for hollow anatomical structure
US7597882B2 (en) * 2006-04-24 2009-10-06 Incept Llc Protein crosslinkers, crosslinking methods and applications thereof
US8019435B2 (en) 2006-05-02 2011-09-13 Boston Scientific Scimed, Inc. Control of arterial smooth muscle tone
US7872068B2 (en) 2006-05-30 2011-01-18 Incept Llc Materials formable in situ within a medical device
WO2007140797A1 (en) * 2006-06-02 2007-12-13 Occlutech Gmbh Occlusion instrument for closing a cardiac auricle
WO2008006118A2 (en) * 2006-07-07 2008-01-10 Bioassets Development Corporation Novel regimens for treating diseases and disorders
JP2009545417A (en) * 2006-08-04 2009-12-24 ノースゲート テクノロジーズ インコーポレイテッド Detention port for access to the body
JP5513115B2 (en) * 2006-09-11 2014-06-04 プルーロームド インコーポレイテッド Atraumatic occlusion balloon and skirt and method of use thereof
WO2008033964A2 (en) 2006-09-13 2008-03-20 Accessclosure, Inc. Apparatus for sealing a vascular puncture
US9820688B2 (en) 2006-09-15 2017-11-21 Acclarent, Inc. Sinus illumination lightwire device
WO2008049087A2 (en) 2006-10-18 2008-04-24 Minnow Medical, Inc. System for inducing desirable temperature effects on body tissue
WO2008049082A2 (en) 2006-10-18 2008-04-24 Minnow Medical, Inc. Inducing desirable temperature effects on body tissue
CA2666661C (en) 2006-10-18 2015-01-20 Minnow Medical, Inc. Tuned rf energy and electrical tissue characterization for selective treatment of target tissues
US7845533B2 (en) 2007-06-22 2010-12-07 Tyco Healthcare Group Lp Detachable buttress material retention systems for use with a surgical stapling device
US8414927B2 (en) 2006-11-03 2013-04-09 Boston Scientific Scimed, Inc. Cross-linked polymer particles
US20100082058A1 (en) * 2007-01-23 2010-04-01 Kassab Ghassan S Devices, systems and methods for controlling local blood pressure
AU2008214319A1 (en) * 2007-02-06 2008-08-14 Incept, Llc Polymerization with precipitation of proteins for elution in physiological solution
KR20160089544A (en) * 2007-02-22 2016-07-27 플루로메드, 인코포레이티드 Use of reverse thermosensitive polymers to control biological fluid flow following a medical procedure
US20080220047A1 (en) 2007-03-05 2008-09-11 Sawhney Amarpreet S Low-swelling biocompatible hydrogels
US20090227689A1 (en) 2007-03-05 2009-09-10 Bennett Steven L Low-Swelling Biocompatible Hydrogels
US20090227981A1 (en) 2007-03-05 2009-09-10 Bennett Steven L Low-Swelling Biocompatible Hydrogels
EP3087929B1 (en) 2007-03-06 2020-04-29 Covidien LP Surgical stapling apparatus
US7665646B2 (en) 2007-06-18 2010-02-23 Tyco Healthcare Group Lp Interlocking buttress material retention system
CN101842061A (en) 2007-06-25 2010-09-22 微排放器公司 Self-expanding prosthesis
US9125807B2 (en) 2007-07-09 2015-09-08 Incept Llc Adhesive hydrogels for ophthalmic drug delivery
US8480651B2 (en) * 2007-08-02 2013-07-09 Covidien Lp Cannula system
GB0715514D0 (en) * 2007-08-10 2007-09-19 Tissuemed Ltd Coated medical devices
US8241609B2 (en) * 2007-08-24 2012-08-14 E I Du Pont De Nemours And Company Method for embolization using liquid embolic materials
US8668712B2 (en) 2007-08-31 2014-03-11 BiO2 Medical, Inc. Multi-lumen central access vena cava filter apparatus and method of using same
US9687333B2 (en) 2007-08-31 2017-06-27 BiO2 Medical, Inc. Reduced profile central venous access catheter with vena cava filter and method
US9039728B2 (en) 2007-08-31 2015-05-26 BiO2 Medical, Inc. IVC filter catheter with imaging modality
US8613753B2 (en) 2007-08-31 2013-12-24 BiO2 Medical, Inc. Multi-lumen central access vena cava filter apparatus and method of using same
US10376685B2 (en) 2007-08-31 2019-08-13 Mermaid Medical Vascular Aps Thrombus detection device and method
US8568385B2 (en) * 2007-09-11 2013-10-29 Boston Scientific Scimed, Inc. Device and method for restricting blood flow to fibroids
US7993367B2 (en) * 2007-09-28 2011-08-09 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
WO2009059217A2 (en) 2007-11-02 2009-05-07 Incept, Llc Apparatus and methods for sealing a vascular puncture
GB0722820D0 (en) 2007-11-21 2008-01-02 Smith & Nephew Vacuum assisted wound dressing
WO2009067711A2 (en) 2007-11-21 2009-05-28 T.J. Smith & Nephew, Limited Suction device and dressing
EP3360519B1 (en) 2007-11-21 2020-11-18 Smith & Nephew plc Wound dressing
GB0723875D0 (en) 2007-12-06 2008-01-16 Smith & Nephew Wound management
US11253399B2 (en) 2007-12-06 2022-02-22 Smith & Nephew Plc Wound filling apparatuses and methods
US7862538B2 (en) * 2008-02-04 2011-01-04 Incept Llc Surgical delivery system for medical sealant
GB0803564D0 (en) 2008-02-27 2008-04-02 Smith & Nephew Fluid collection
US20090217932A1 (en) * 2008-03-03 2009-09-03 Ethicon Endo-Surgery, Inc. Intraluminal tissue markers
US8282612B1 (en) 2008-03-07 2012-10-09 Denise H. Miller Methods and devices for intrauterine absorption
US20090234430A1 (en) * 2008-03-17 2009-09-17 James Fleming Weave modification for increased durability in graft material
US8029533B2 (en) 2008-04-04 2011-10-04 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
US9364206B2 (en) 2008-04-04 2016-06-14 Access Closure, Inc. Apparatus and methods for sealing a vascular puncture
JP5663471B2 (en) 2008-04-25 2015-02-04 ネリックス・インコーポレーテッド Stent / graft delivery system
US10028747B2 (en) 2008-05-01 2018-07-24 Aneuclose Llc Coils with a series of proximally-and-distally-connected loops for occluding a cerebral aneurysm
US10716573B2 (en) 2008-05-01 2020-07-21 Aneuclose Janjua aneurysm net with a resilient neck-bridging portion for occluding a cerebral aneurysm
JP2011522615A (en) 2008-06-04 2011-08-04 ネリックス・インコーポレーテッド Sealing device and method of use
US9271706B2 (en) 2008-08-12 2016-03-01 Covidien Lp Medical device for wound closure and method of use
JP5616891B2 (en) 2008-08-26 2014-10-29 セント ジュード メディカル インコーポレイテッドSt. Jude Medical, Inc. Method and system for sealing a percutaneous puncture
US9173669B2 (en) 2008-09-12 2015-11-03 Pneumrx, Inc. Enhanced efficacy lung volume reduction devices, methods, and systems
WO2010033629A1 (en) 2008-09-18 2010-03-25 Acclarent, Inc. Methods and apparatus for treating disorders of the ear nose and throat
US8450529B2 (en) 2008-10-02 2013-05-28 Covidien Lp Branched polyamines and formulations thereof for use in medical devices
US10070888B2 (en) 2008-10-03 2018-09-11 Femasys, Inc. Methods and devices for sonographic imaging
US9554826B2 (en) 2008-10-03 2017-01-31 Femasys, Inc. Contrast agent injection system for sonographic imaging
US9555228B2 (en) 2008-10-15 2017-01-31 Dtherapeutics, Llc Systems, devices, and methods for localized drug delivery
US20100100123A1 (en) 2008-10-17 2010-04-22 Confluent Surgical, Inc. Hemostatic implant
US9889230B2 (en) * 2008-10-17 2018-02-13 Covidien Lp Hemostatic implant
WO2010043979A2 (en) 2008-10-17 2010-04-22 Sofradim Production Auto-sealant matrix for tissue repair
JP2012508618A (en) 2008-11-12 2012-04-12 アクセスクロージャー,インク. Device and method for closing a vascular puncture
WO2010056745A1 (en) 2008-11-17 2010-05-20 Minnow Medical, Inc. Selective accumulation of energy with or without knowledge of tissue topography
US20100147921A1 (en) 2008-12-16 2010-06-17 Lee Olson Surgical Apparatus Including Surgical Buttress
US11090387B2 (en) * 2008-12-22 2021-08-17 The Trustees Of The University Of Pennsylvania Hydrolytically degradable polysaccharide hydrogels
CA2750242C (en) 2009-02-12 2018-05-22 Incept, Llc Drug delivery through hydrogel plugs
US9486215B2 (en) 2009-03-31 2016-11-08 Covidien Lp Surgical stapling apparatus
EP2424447A2 (en) 2009-05-01 2012-03-07 Endologix, Inc. Percutaneous method and device to treat dissections
US10772717B2 (en) 2009-05-01 2020-09-15 Endologix, Inc. Percutaneous method and device to treat dissections
JP5684239B2 (en) 2009-05-04 2015-03-11 インセプト・リミテッド・ライアビリティ・カンパニーIncept Llc Biomaterial for track and puncture closure
CN102573700B (en) 2009-05-18 2014-12-17 纽姆克斯股份有限公司 Cross-sectional modification during deployment of an elongate lung volume reduction device
US20110022026A1 (en) * 2009-07-21 2011-01-27 Lake Region Manufacturing, Inc. d/b/a Lake Region Medical. Inc. Methods and Devices for Delivering Drugs Using Drug-Delivery or Drug-Coated Guidewires
WO2011017123A2 (en) 2009-07-27 2011-02-10 Endologix, Inc. Stent graft
US9592108B2 (en) 2009-07-29 2017-03-14 Covidien Lp System and method of laparoscopic use of hemostatic patch
US9173817B2 (en) 2009-08-24 2015-11-03 Arsenal Medical, Inc. In situ forming hemostatic foam implants
US9044580B2 (en) 2009-08-24 2015-06-02 Arsenal Medical, Inc. In-situ forming foams with outer layer
US10420862B2 (en) 2009-08-24 2019-09-24 Aresenal AAA, LLC. In-situ forming foams for treatment of aneurysms
US20110081398A1 (en) * 2009-10-01 2011-04-07 Tyco Healthcare Group Lp Multi-mechanism surgical compositions
US8470355B2 (en) 2009-10-01 2013-06-25 Covidien Lp Mesh implant
US20110081701A1 (en) * 2009-10-02 2011-04-07 Timothy Sargeant Surgical compositions
US8968785B2 (en) 2009-10-02 2015-03-03 Covidien Lp Surgical compositions
US8617206B2 (en) 2009-10-08 2013-12-31 Covidien Lp Wound closure device
US20110087273A1 (en) * 2009-10-08 2011-04-14 Tyco Healthcare Group Lp Wound Closure Device
US20110087274A1 (en) * 2009-10-08 2011-04-14 Tyco Healtcare Group LP, New Haven, Ct Wound Closure Device
US9833225B2 (en) * 2009-10-08 2017-12-05 Covidien Lp Wound closure device
US20150231409A1 (en) 2009-10-15 2015-08-20 Covidien Lp Buttress brachytherapy and integrated staple line markers for margin identification
US10293553B2 (en) 2009-10-15 2019-05-21 Covidien Lp Buttress brachytherapy and integrated staple line markers for margin identification
US20110093057A1 (en) * 2009-10-16 2011-04-21 Confluent Surgical, Inc. Mitigating Thrombus Formation On Medical Devices By Influencing pH Microenvironment Near The Surface
US9445795B2 (en) * 2009-10-16 2016-09-20 Confluent Surgical, Inc. Prevention of premature gelling of delivery devices for pH dependent forming materials
US8434489B2 (en) 2009-10-23 2013-05-07 Conceptus, Inc. Contraceptive devices and methods
US20110108199A1 (en) * 2009-11-10 2011-05-12 Tyco Healthcare Group Lp Hemostatic Tapes and Dispensers Therefor
US20110112572A1 (en) 2009-11-10 2011-05-12 Tyco Healthcare Group Lp Hemostatic Tapes and Dispensers Therefor
US9358140B1 (en) 2009-11-18 2016-06-07 Aneuclose Llc Stent with outer member to embolize an aneurysm
US8858592B2 (en) * 2009-11-24 2014-10-14 Covidien Lp Wound plugs
IN2012DN05177A (en) 2009-12-15 2015-10-23 Incept Llc
US20110276078A1 (en) 2009-12-30 2011-11-10 Nellix, Inc. Filling structure for a graft system and methods of use
US20110218606A1 (en) * 2010-03-02 2011-09-08 Medtronic Vascular, Inc. Methods for Stabilizing Femoral Vessels
CA2730598C (en) 2010-03-16 2018-03-13 Confluent Surgical, Inc. Modulating drug release rate by controlling the kinetics of the ph transition in hydrogels
EP2555812B1 (en) 2010-04-05 2019-09-04 Neomend, Inc. Systems, devices, methods for delivering hydrogel compositions with self-purging to prevent clogging
JP2013523318A (en) 2010-04-09 2013-06-17 べシックス・バスキュラー・インコーポレイテッド Power generation and control equipment for tissue treatment
US9192790B2 (en) 2010-04-14 2015-11-24 Boston Scientific Scimed, Inc. Focused ultrasonic renal denervation
US9061095B2 (en) 2010-04-27 2015-06-23 Smith & Nephew Plc Wound dressing and method of use
US8697111B2 (en) 2010-05-12 2014-04-15 Covidien Lp Osteochondral implant comprising osseous phase and chondral phase
US8754564B2 (en) 2010-05-27 2014-06-17 Covidien Lp Hydrogel implants with varying degrees of crosslinking
US8591929B2 (en) 2010-05-27 2013-11-26 Covidien Lp Hydrogel implants with varying degrees of crosslinking
US8591950B2 (en) 2010-05-27 2013-11-26 Covidien Lp Hydrogel implants with varying degrees of crosslinking
US8734824B2 (en) 2010-05-27 2014-05-27 Covidien LLP Hydrogel implants with varying degrees of crosslinking
US8968783B2 (en) 2010-05-27 2015-03-03 Covidien Lp Hydrogel implants with varying degrees of crosslinking
US8883185B2 (en) 2010-05-27 2014-11-11 Covidien Lp Hydrogel implants with varying degrees of crosslinking
US8734930B2 (en) 2010-05-27 2014-05-27 Covidien Lp Hydrogel implants with varying degrees of crosslinking
US8473067B2 (en) 2010-06-11 2013-06-25 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
US8302323B2 (en) 2010-06-21 2012-11-06 Confluent Surgical, Inc. Hemostatic patch
US20110313450A1 (en) 2010-06-21 2011-12-22 Jason Fortier Hemostatic patch
WO2012002944A1 (en) 2010-06-29 2012-01-05 Artventive Medical Group, Inc. Reducing flow through a tubular structure
US9247942B2 (en) 2010-06-29 2016-02-02 Artventive Medical Group, Inc. Reversible tubal contraceptive device
US9232805B2 (en) 2010-06-29 2016-01-12 Biocure, Inc. In-situ forming hydrogel wound dressings containing antimicrobial agents
GB201011173D0 (en) 2010-07-02 2010-08-18 Smith & Nephew Provision of wound filler
US9211175B2 (en) 2010-07-08 2015-12-15 Covidien Lp Self-detachable medical devices
WO2012012772A2 (en) * 2010-07-22 2012-01-26 The Johns Hopkins University Drug eluting hydrogels for catheter delivery
US9155589B2 (en) 2010-07-30 2015-10-13 Boston Scientific Scimed, Inc. Sequential activation RF electrode set for renal nerve ablation
US9358365B2 (en) 2010-07-30 2016-06-07 Boston Scientific Scimed, Inc. Precision electrode movement control for renal nerve ablation
US9463062B2 (en) 2010-07-30 2016-10-11 Boston Scientific Scimed, Inc. Cooled conductive balloon RF catheter for renal nerve ablation
US9084609B2 (en) 2010-07-30 2015-07-21 Boston Scientific Scime, Inc. Spiral balloon catheter for renal nerve ablation
US9408661B2 (en) 2010-07-30 2016-08-09 Patrick A. Haverkost RF electrodes on multiple flexible wires for renal nerve ablation
US8961501B2 (en) 2010-09-17 2015-02-24 Incept, Llc Method for applying flowable hydrogels to a cornea
US9155492B2 (en) 2010-09-24 2015-10-13 Acclarent, Inc. Sinus illumination lightwire device
US9149277B2 (en) 2010-10-18 2015-10-06 Artventive Medical Group, Inc. Expandable device delivery
US8974451B2 (en) 2010-10-25 2015-03-10 Boston Scientific Scimed, Inc. Renal nerve ablation using conductive fluid jet and RF energy
US9220558B2 (en) 2010-10-27 2015-12-29 Boston Scientific Scimed, Inc. RF renal denervation catheter with multiple independent electrodes
US9028485B2 (en) 2010-11-15 2015-05-12 Boston Scientific Scimed, Inc. Self-expanding cooling electrode for renal nerve ablation
US9668811B2 (en) 2010-11-16 2017-06-06 Boston Scientific Scimed, Inc. Minimally invasive access for renal nerve ablation
US9089350B2 (en) 2010-11-16 2015-07-28 Boston Scientific Scimed, Inc. Renal denervation catheter with RF electrode and integral contrast dye injection arrangement
US9326751B2 (en) 2010-11-17 2016-05-03 Boston Scientific Scimed, Inc. Catheter guidance of external energy for renal denervation
US9393100B2 (en) 2010-11-17 2016-07-19 Endologix, Inc. Devices and methods to treat vascular dissections
US9060761B2 (en) 2010-11-18 2015-06-23 Boston Scientific Scime, Inc. Catheter-focused magnetic field induced renal nerve ablation
US9192435B2 (en) 2010-11-22 2015-11-24 Boston Scientific Scimed, Inc. Renal denervation catheter with cooled RF electrode
US9023034B2 (en) 2010-11-22 2015-05-05 Boston Scientific Scimed, Inc. Renal ablation electrode with force-activatable conduction apparatus
RU2597393C2 (en) 2010-11-25 2016-09-10 СМИТ ЭНД НЕФЬЮ ПиЭлСи Composition i-ii, article containing same and use thereof
GB201020005D0 (en) 2010-11-25 2011-01-12 Smith & Nephew Composition 1-1
WO2012078522A1 (en) * 2010-12-03 2012-06-14 Olympus Endo Technology America Inc. Rotate-to-advance catheterization system
US20120157993A1 (en) 2010-12-15 2012-06-21 Jenson Mark L Bipolar Off-Wall Electrode Device for Renal Nerve Ablation
US8518440B2 (en) 2010-12-21 2013-08-27 Confluent Surgical, Inc. Biodegradable osmotic pump implant for drug delivery
US9220561B2 (en) 2011-01-19 2015-12-29 Boston Scientific Scimed, Inc. Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury
US9820728B2 (en) 2011-01-19 2017-11-21 Access Closure, Inc. Apparatus and methods for sealing a vascular puncture
EP3821820A1 (en) 2011-01-19 2021-05-19 Access Closure, Inc. Apparatus and methods of manufacturing a sealing a vascular puncture
US8801768B2 (en) * 2011-01-21 2014-08-12 Endologix, Inc. Graft systems having semi-permeable filling structures and methods for their use
US9084602B2 (en) 2011-01-26 2015-07-21 Covidien Lp Buttress film with hemostatic action for surgical stapling apparatus
US8479968B2 (en) 2011-03-10 2013-07-09 Covidien Lp Surgical instrument buttress attachment
US9486404B2 (en) 2011-03-28 2016-11-08 The Trustees Of The University Of Pennsylvania Infarction treatment compositions and methods
US9415195B2 (en) 2011-04-06 2016-08-16 Engologix, Inc. Method and system for treating aneurysms
CA2832311A1 (en) 2011-04-08 2012-11-29 Covidien Lp Iontophoresis drug delivery system and method for denervation of the renal sympathetic nerve and iontophoretic drug delivery
CN103930061B (en) 2011-04-25 2016-09-14 美敦力阿迪安卢森堡有限责任公司 Relevant low temperature sacculus for restricted conduit wall cryogenic ablation limits the device and method disposed
JP6138116B2 (en) * 2011-05-03 2017-05-31 アバンター・パフォーマンス・マテリアルズ・インコーポレイテッドAvantor Performance Materials, Inc. Novel chromatographic media based on allylamine and allylamine derivatives for protein purification
US9386968B2 (en) 2011-05-11 2016-07-12 Access Closure, Inc. Apparatus and methods for sealing a vascular puncture
AU2012275265B2 (en) 2011-06-29 2017-05-04 Covidien Lp Dissolution of oxidized cellulose
WO2013013156A2 (en) 2011-07-20 2013-01-24 Boston Scientific Scimed, Inc. Percutaneous devices and methods to visualize, target and ablate nerves
EP2734264B1 (en) 2011-07-22 2018-11-21 Boston Scientific Scimed, Inc. Nerve modulation system with a nerve modulation element positionable in a helical guide
WO2013025436A1 (en) 2011-08-12 2013-02-21 Boston Scientific Scimed, Inc. Anastomosis kit for radical prostatectomy procedure
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
WO2013055826A1 (en) 2011-10-10 2013-04-18 Boston Scientific Scimed, Inc. Medical devices including ablation electrodes
US10085799B2 (en) 2011-10-11 2018-10-02 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US9420955B2 (en) 2011-10-11 2016-08-23 Boston Scientific Scimed, Inc. Intravascular temperature monitoring system and method
US9364284B2 (en) 2011-10-12 2016-06-14 Boston Scientific Scimed, Inc. Method of making an off-wall spacer cage
US9162046B2 (en) 2011-10-18 2015-10-20 Boston Scientific Scimed, Inc. Deflectable medical devices
US9079000B2 (en) 2011-10-18 2015-07-14 Boston Scientific Scimed, Inc. Integrated crossing balloon catheter
US8993831B2 (en) 2011-11-01 2015-03-31 Arsenal Medical, Inc. Foam and delivery system for treatment of postpartum hemorrhage
US8584920B2 (en) 2011-11-04 2013-11-19 Covidien Lp Surgical stapling apparatus including releasable buttress
CN108095821B (en) 2011-11-08 2021-05-25 波士顿科学西美德公司 Orifice renal nerve ablation
WO2013074813A1 (en) 2011-11-15 2013-05-23 Boston Scientific Scimed, Inc. Device and methods for renal nerve modulation monitoring
US9119632B2 (en) 2011-11-21 2015-09-01 Boston Scientific Scimed, Inc. Deflectable renal nerve ablation catheter
US20150159066A1 (en) 2011-11-25 2015-06-11 Smith & Nephew Plc Composition, apparatus, kit and method and uses thereof
WO2013086015A1 (en) 2011-12-05 2013-06-13 Incept, Llc Medical organogel processes and compositions
US9351731B2 (en) 2011-12-14 2016-05-31 Covidien Lp Surgical stapling apparatus including releasable surgical buttress
US9237892B2 (en) 2011-12-14 2016-01-19 Covidien Lp Buttress attachment to the cartridge surface
US8967448B2 (en) 2011-12-14 2015-03-03 Covidien Lp Surgical stapling apparatus including buttress attachment via tabs
US9113885B2 (en) 2011-12-14 2015-08-25 Covidien Lp Buttress assembly for use with surgical stapling device
US9265969B2 (en) 2011-12-21 2016-02-23 Cardiac Pacemakers, Inc. Methods for modulating cell function
AU2012358143B2 (en) 2011-12-23 2015-06-11 Boston Scientific Scimed, Inc. Expandable balloon or an electrode pad with a heat sensing device
US9433760B2 (en) 2011-12-28 2016-09-06 Boston Scientific Scimed, Inc. Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements
US9050106B2 (en) 2011-12-29 2015-06-09 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US9010609B2 (en) 2012-01-26 2015-04-21 Covidien Lp Circular stapler including buttress
US9010612B2 (en) 2012-01-26 2015-04-21 Covidien Lp Buttress support design for EEA anvil
US9326773B2 (en) 2012-01-26 2016-05-03 Covidien Lp Surgical device including buttress material
US9931116B2 (en) 2012-02-10 2018-04-03 Covidien Lp Buttress composition
US8820606B2 (en) 2012-02-24 2014-09-02 Covidien Lp Buttress retention system for linear endostaplers
US9757105B2 (en) 2012-03-23 2017-09-12 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
US8721680B2 (en) 2012-03-23 2014-05-13 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
US10660703B2 (en) 2012-05-08 2020-05-26 Boston Scientific Scimed, Inc. Renal nerve modulation devices
US9168227B2 (en) 2012-05-31 2015-10-27 Covidien Lp Multi-encapsulated microspheres made with oxidized cellulose for in-situ reactions
US9271937B2 (en) 2012-05-31 2016-03-01 Covidien Lp Oxidized cellulose microspheres
JP6480327B2 (en) 2012-06-14 2019-03-06 マイクロベンション インコーポレイテッドMicrovention, Inc. Polymer therapeutic composition
US9499636B2 (en) 2012-06-28 2016-11-22 Covidien Lp Dissolution of oxidized cellulose and particle preparation by cross-linking with multivalent cations
US9265652B2 (en) 2012-08-14 2016-02-23 Contramed, Llc Intrauterine contraceptive device
US9089418B2 (en) 2012-08-14 2015-07-28 Contramed, Llc Intrauterine contraceptive device
US20140048580A1 (en) 2012-08-20 2014-02-20 Covidien Lp Buttress attachment features for surgical stapling apparatus
CN104540465A (en) 2012-08-24 2015-04-22 波士顿科学西美德公司 Intravascular catheter with a balloon comprising separate microporous regions
US9149176B2 (en) 2012-09-13 2015-10-06 Emmy Medical, Llc 4-way cystoscopy catheter
WO2014043586A1 (en) * 2012-09-13 2014-03-20 Have Glass, Llc 4-way cystoscopy catheter with low profile balloon
WO2014043687A2 (en) 2012-09-17 2014-03-20 Boston Scientific Scimed, Inc. Self-positioning electrode system and method for renal nerve modulation
CA2826786A1 (en) 2012-09-17 2014-03-17 Confluent Surgical, Inc. Multi-encapsulated formulations made with oxidized cellulose
WO2014047411A1 (en) 2012-09-21 2014-03-27 Boston Scientific Scimed, Inc. System for nerve modulation and innocuous thermal gradient nerve block
WO2014047454A2 (en) 2012-09-21 2014-03-27 Boston Scientific Scimed, Inc. Self-cooling ultrasound ablation catheter
JP6074051B2 (en) 2012-10-10 2017-02-01 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Intravascular neuromodulation system and medical device
US9161753B2 (en) 2012-10-10 2015-10-20 Covidien Lp Buttress fixation for a circular stapler
CA2887604C (en) 2012-10-15 2021-05-18 Microvention, Inc. Liquid embolic compositions and uses thereof for treating vascular conditions
US9078786B1 (en) 2012-10-19 2015-07-14 Denise H. Miller Methods and devices for collecting body fluids
WO2014066547A1 (en) * 2012-10-23 2014-05-01 Scheinfeld Andrew H Blood loss monitoring and quantification devices, systems, and methods
US20140131418A1 (en) 2012-11-09 2014-05-15 Covidien Lp Surgical Stapling Apparatus Including Buttress Attachment
MX2012014854A (en) * 2012-12-17 2014-06-20 Luis Renee Gonzalez Lucano Catheter for the intraurethral application of fibrin.
WO2014105820A1 (en) 2012-12-28 2014-07-03 Boston Scientific Scimed, Inc. Methods, compositions and kits for surgical repair
US9597426B2 (en) 2013-01-25 2017-03-21 Covidien Lp Hydrogel filled barbed suture
US8984733B2 (en) 2013-02-05 2015-03-24 Artventive Medical Group, Inc. Bodily lumen occlusion
US9095344B2 (en) 2013-02-05 2015-08-04 Artventive Medical Group, Inc. Methods and apparatuses for blood vessel occlusion
US20160220235A1 (en) 2013-02-14 2016-08-04 Access Closure, Inc. Vascular closure apparatus and related method
US20140239047A1 (en) 2013-02-28 2014-08-28 Covidien Lp Adherence concepts for non-woven absorbable felt buttresses
US9782173B2 (en) 2013-03-07 2017-10-10 Covidien Lp Circular stapling device including buttress release mechanism
WO2014163987A1 (en) 2013-03-11 2014-10-09 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
WO2014143571A1 (en) 2013-03-11 2014-09-18 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
EP2968873A4 (en) * 2013-03-13 2016-10-26 Applied Cardiovascular Solutions Llc Methods, compositions, and devices for the occlusion of cavities and passageways
US9808311B2 (en) 2013-03-13 2017-11-07 Boston Scientific Scimed, Inc. Deflectable medical devices
CN105120910B (en) 2013-03-14 2019-04-12 恩朵罗杰克斯股份有限公司 Method for material to be formed in situ in medical instrument
US10413566B2 (en) 2013-03-15 2019-09-17 Covidien Lp Thixotropic oxidized cellulose solutions and medical applications thereof
US9782430B2 (en) 2013-03-15 2017-10-10 Covidien Lp Resorbable oxidized cellulose embolization solution
US10328095B2 (en) 2013-03-15 2019-06-25 Covidien Lp Resorbable oxidized cellulose embolization microspheres
US20160120706A1 (en) 2013-03-15 2016-05-05 Smith & Nephew Plc Wound dressing sealant and use thereof
CN105228546B (en) 2013-03-15 2017-11-14 波士顿科学国际有限公司 Utilize the impedance-compensated medicine equipment and method that are used to treat hypertension
US10265122B2 (en) 2013-03-15 2019-04-23 Boston Scientific Scimed, Inc. Nerve ablation devices and related methods of use
US9827039B2 (en) 2013-03-15 2017-11-28 Boston Scientific Scimed, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US20170128695A1 (en) * 2013-05-29 2017-05-11 Paul Speiser Three lumen balloon catheter apparatus
US9737306B2 (en) 2013-06-14 2017-08-22 Artventive Medical Group, Inc. Implantable luminal devices
US9636116B2 (en) 2013-06-14 2017-05-02 Artventive Medical Group, Inc. Implantable luminal devices
US9737308B2 (en) 2013-06-14 2017-08-22 Artventive Medical Group, Inc. Catheter-assisted tumor treatment
US10149968B2 (en) 2013-06-14 2018-12-11 Artventive Medical Group, Inc. Catheter-assisted tumor treatment
US9775928B2 (en) 2013-06-18 2017-10-03 Covidien Lp Adhesive barbed filament
JP2016524949A (en) 2013-06-21 2016-08-22 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Medical device for renal nerve ablation having a rotatable shaft
EP3010437A1 (en) 2013-06-21 2016-04-27 Boston Scientific Scimed, Inc. Renal denervation balloon catheter with ride along electrode support
US9707036B2 (en) 2013-06-25 2017-07-18 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation using localized indifferent electrodes
AU2014284558B2 (en) 2013-07-01 2017-08-17 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
EP3019106A1 (en) 2013-07-11 2016-05-18 Boston Scientific Scimed, Inc. Medical device with stretchable electrode assemblies
US10660698B2 (en) 2013-07-11 2020-05-26 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation
EP3049007B1 (en) 2013-07-19 2019-06-12 Boston Scientific Scimed, Inc. Spiral bipolar electrode renal denervation balloon
JP6122217B2 (en) 2013-07-22 2017-04-26 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Renal nerve ablation medical device
WO2015013205A1 (en) 2013-07-22 2015-01-29 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
US9579257B2 (en) * 2013-08-20 2017-02-28 Anutra Medical, Inc. Haptic feedback and audible output syringe
CN105473093B (en) 2013-08-22 2019-02-05 波士顿科学国际有限公司 Flexible circuit with the improved adhesion strength to renal nerve modulation sacculus
CN105555218B (en) 2013-09-04 2019-01-15 波士顿科学国际有限公司 With radio frequency (RF) foley's tube rinsed with cooling capacity
EP3043733A1 (en) 2013-09-13 2016-07-20 Boston Scientific Scimed, Inc. Ablation balloon with vapor deposited cover layer
US9445853B2 (en) * 2013-09-18 2016-09-20 Globus Medical, Inc Intervertebral dosing device and method
US9687166B2 (en) 2013-10-14 2017-06-27 Boston Scientific Scimed, Inc. High resolution cardiac mapping electrode array catheter
US11246654B2 (en) 2013-10-14 2022-02-15 Boston Scientific Scimed, Inc. Flexible renal nerve ablation devices and related methods of use and manufacture
US10918516B2 (en) 2013-10-14 2021-02-16 Sebela Vlc Limited Intrauterine device with controlled copper ion elution
US10188546B2 (en) 2013-10-14 2019-01-29 Sebela Vlc Limited Intrauterine device with controlled copper ion elution
WO2015057584A1 (en) 2013-10-15 2015-04-23 Boston Scientific Scimed, Inc. Medical device balloon
US9770606B2 (en) 2013-10-15 2017-09-26 Boston Scientific Scimed, Inc. Ultrasound ablation catheter with cooling infusion and centering basket
US9180040B2 (en) 2013-10-18 2015-11-10 Contramed, Llc Intrauterine device with retrieval thread
WO2015057961A1 (en) 2013-10-18 2015-04-23 Boston Scientific Scimed, Inc. Balloon catheters with flexible conducting wires and related methods of use and manufacture
WO2015061457A1 (en) 2013-10-25 2015-04-30 Boston Scientific Scimed, Inc. Embedded thermocouple in denervation flex circuit
US10842969B2 (en) 2013-10-25 2020-11-24 Mercator Medsystems, Inc. Systems and methods of treating malacia by local delivery of hydrogel to augment tissue
WO2015103617A1 (en) 2014-01-06 2015-07-09 Boston Scientific Scimed, Inc. Tear resistant flex circuit assembly
US11000679B2 (en) 2014-02-04 2021-05-11 Boston Scientific Scimed, Inc. Balloon protection and rewrapping devices and related methods of use
EP3102136B1 (en) 2014-02-04 2018-06-27 Boston Scientific Scimed, Inc. Alternative placement of thermal sensors on bipolar electrode
JP2017505702A (en) 2014-02-18 2017-02-23 クラービスタ メディカル, インコーポレイテッドClarvista Medical, Inc. Modular intraocular lens design, apparatus and method
US9572595B1 (en) 2014-03-05 2017-02-21 Northgate Technologies Inc. In-dwelling port for access into a body
JP6645979B2 (en) 2014-03-07 2020-02-14 エンドーロジックス インコーポレイテッド Improved method of forming hydrogels and materials thereof
WO2015153828A1 (en) 2014-04-04 2015-10-08 Hyperbranch Medical Technology, Inc. Extended tip spray applicator for two-component surgical selant, and methods of use thereof
US9844378B2 (en) 2014-04-29 2017-12-19 Covidien Lp Surgical stapling apparatus and methods of adhering a surgical buttress thereto
US10363043B2 (en) 2014-05-01 2019-07-30 Artventive Medical Group, Inc. Treatment of incompetent vessels
US10709490B2 (en) 2014-05-07 2020-07-14 Medtronic Ardian Luxembourg S.A.R.L. Catheter assemblies comprising a direct heating element for renal neuromodulation and associated systems and methods
WO2016004283A1 (en) * 2014-07-02 2016-01-07 The Cleveland Clinic Foundation Anastomosis devices and methods of using same
IL282559B (en) 2014-07-17 2022-07-01 Univ California Controllable self-annealing microgel particles for biomedical applications
US10390838B1 (en) 2014-08-20 2019-08-27 Pneumrx, Inc. Tuned strength chronic obstructive pulmonary disease treatment
US9999427B2 (en) * 2014-09-22 2018-06-19 Arsenal Medical, Inc. Methods, devices and systems for filling body cavities
US10449152B2 (en) 2014-09-26 2019-10-22 Covidien Lp Drug loaded microspheres for post-operative chronic pain
US9295752B1 (en) 2014-09-30 2016-03-29 Covidien Lp Bioadhesive for occluding vessels
WO2016065245A1 (en) * 2014-10-24 2016-04-28 Incept, Llc Extra luminal scaffold
US9743917B2 (en) 2014-12-19 2017-08-29 Cohera Medical, Inc. Devices for applying surgical sealants
US10835216B2 (en) 2014-12-24 2020-11-17 Covidien Lp Spinneret for manufacture of melt blown nonwoven fabric
US10470767B2 (en) 2015-02-10 2019-11-12 Covidien Lp Surgical stapling instrument having ultrasonic energy delivery
US11382731B2 (en) 2015-02-27 2022-07-12 Covidien Lp Medical devices with sealing properties
WO2016164519A1 (en) 2015-04-10 2016-10-13 Covidien Lp Surgical stapler with integrated bladder
CA2925606A1 (en) 2015-04-23 2016-10-23 Covidien Lp Resorbable oxidized cellulose embolization solution
CN107921237A (en) 2015-04-27 2018-04-17 反射医学公司 Sympathetic nerve cardiopulmonary neural modulation system and method
AU2016297642A1 (en) 2015-07-22 2018-02-15 Incept, Llc Coated punctal plug
WO2017039641A1 (en) * 2015-09-01 2017-03-09 Contramed, Llc System for fallopian tube occlusion
CA3004745A1 (en) 2015-11-12 2017-05-18 University Of Virginia Patent Foundation Compositions and methods for vas-occlusive contraception and reversal thereof
CA3006303C (en) 2015-11-25 2023-11-14 Incept, Llc Shape changing drug delivery devices and methods
CN105411655B (en) * 2015-12-17 2018-01-19 王婧 A kind of gynaecology's hemostatic bag
US11246879B2 (en) 2016-02-09 2022-02-15 Tulai Therapeutics, Inc. Methods, agents, and devices for local neuromodulation of autonomic nerves
WO2017142879A1 (en) 2016-02-16 2017-08-24 The Regents Of The University Of California Methods for immune system modulation with microporous annealed particle gels
JP6698257B2 (en) * 2016-02-22 2020-05-27 朝日インテック株式会社 catheter
US10813644B2 (en) 2016-04-01 2020-10-27 Artventive Medical Group, Inc. Occlusive implant and delivery system
EP3254723A1 (en) * 2016-06-10 2017-12-13 Celyad S.A. Catheter for delivering a therapeutic agent into a substrate
US10959731B2 (en) 2016-06-14 2021-03-30 Covidien Lp Buttress attachment for surgical stapling instrument
AU2017290353B2 (en) 2016-06-29 2023-05-18 Tulavi Therapeutics, Inc. Treatment of sepsis and related inflammatory conditions by local neuromodulation of the autonomic nervous system
AU2017204280A1 (en) 2016-08-12 2018-03-01 Covidien Lp Thixotropic oxidized cellulose solutions and medical applications thereof
US10625032B2 (en) 2016-08-16 2020-04-21 Ethicon, Inc. Spray tips for simultaneous multi-directional delivery of dissimilar fluids
US10368874B2 (en) 2016-08-26 2019-08-06 Microvention, Inc. Embolic compositions
US11026686B2 (en) 2016-11-08 2021-06-08 Covidien Lp Structure for attaching buttress to anvil and/or cartridge of surgical stapling instrument
CN117582559A (en) 2016-12-29 2024-02-23 泰普治疗公司 Methods and systems for treating a medical implant site
CN110381854A (en) 2017-01-05 2019-10-25 考恩特兰有限公司 Method for being implanted into and reversing stimulating responsive implantation material
US10874768B2 (en) 2017-01-20 2020-12-29 Covidien Lp Drug eluting medical device
US10925607B2 (en) 2017-02-28 2021-02-23 Covidien Lp Surgical stapling apparatus with staple sheath
US10368868B2 (en) 2017-03-09 2019-08-06 Covidien Lp Structure for attaching buttress material to anvil and cartridge of surgical stapling instrument
US11096610B2 (en) 2017-03-28 2021-08-24 Covidien Lp Surgical implants including sensing fibers
US10849625B2 (en) 2017-08-07 2020-12-01 Covidien Lp Surgical buttress retention systems for surgical stapling apparatus
US10945733B2 (en) 2017-08-23 2021-03-16 Covidien Lp Surgical buttress reload and tip attachment assemblies for surgical stapling apparatus
US10576182B2 (en) 2017-10-09 2020-03-03 Microvention, Inc. Radioactive liquid embolic
US11141151B2 (en) 2017-12-08 2021-10-12 Covidien Lp Surgical buttress for circular stapling
US11116561B2 (en) 2018-01-24 2021-09-14 Medtronic Ardian Luxembourg S.A.R.L. Devices, agents, and associated methods for selective modulation of renal nerves
US11065000B2 (en) 2018-02-22 2021-07-20 Covidien Lp Surgical buttresses for surgical stapling apparatus
US10758237B2 (en) 2018-04-30 2020-09-01 Covidien Lp Circular stapling apparatus with pinned buttress
US11284896B2 (en) 2018-05-09 2022-03-29 Covidien Lp Surgical buttress loading and attaching/detaching assemblies
US11426163B2 (en) 2018-05-09 2022-08-30 Covidien Lp Universal linear surgical stapling buttress
US11432818B2 (en) 2018-05-09 2022-09-06 Covidien Lp Surgical buttress assemblies
EP3793622A1 (en) * 2018-05-15 2021-03-24 Incept, LLC Embolic compositions and methods
CN112638437B (en) 2018-07-02 2023-12-08 图拉维治疗股份有限公司 Method and apparatus for forming nerve caps in situ
US11219460B2 (en) 2018-07-02 2022-01-11 Covidien Lp Surgical stapling apparatus with anvil buttress
USD908865S1 (en) 2018-08-17 2021-01-26 Emmy Medical, Llc Catheter
US10806459B2 (en) 2018-09-14 2020-10-20 Covidien Lp Drug patterned reinforcement material for circular anastomosis
US10952729B2 (en) 2018-10-03 2021-03-23 Covidien Lp Universal linear buttress retention/release assemblies and methods
US11253391B2 (en) 2018-11-13 2022-02-22 Contraline, Inc. Systems and methods for delivering biomaterials
US11730472B2 (en) 2019-04-25 2023-08-22 Covidien Lp Surgical system and surgical loading units thereof
US11596403B2 (en) 2019-05-08 2023-03-07 Covidien Lp Surgical stapling device
US11478245B2 (en) 2019-05-08 2022-10-25 Covidien Lp Surgical stapling device
US11571208B2 (en) 2019-10-11 2023-02-07 Covidien Lp Surgical buttress loading units
US11523824B2 (en) 2019-12-12 2022-12-13 Covidien Lp Anvil buttress loading for a surgical stapling apparatus
US20210252185A1 (en) 2020-02-18 2021-08-19 Ethicon, Inc. Melt Blown Dressing with Gradient Density
US11547407B2 (en) 2020-03-19 2023-01-10 Covidien Lp Staple line reinforcement for surgical stapling apparatus
US11337699B2 (en) 2020-04-28 2022-05-24 Covidien Lp Magnesium infused surgical buttress for surgical stapler
US20210379237A1 (en) 2020-06-08 2021-12-09 Ethicon, Inc. Napped Coated Wound Dressing
US20220023488A1 (en) 2020-07-21 2022-01-27 Ethicon, Inc. Sealant Dressing with Removable Intermediate Separating Layer
US20220062492A1 (en) 2020-08-31 2022-03-03 Ethicon, Inc. Sealant Dressing with Protected Reactive Components
US11707276B2 (en) 2020-09-08 2023-07-25 Covidien Lp Surgical buttress assemblies and techniques for surgical stapling
CN111991048B (en) * 2020-09-21 2021-05-25 合肥中纳医学仪器有限公司 Device and equipment for treating esophageal varices surgical bleeding
CN111991049B (en) * 2020-09-21 2021-09-10 合肥中纳医学仪器有限公司 Automatic hemostasis system for esophageal varices operation
US11399833B2 (en) 2020-10-19 2022-08-02 Covidien Lp Anvil buttress attachment for surgical stapling apparatus
US11534170B2 (en) 2021-01-04 2022-12-27 Covidien Lp Anvil buttress attachment for surgical stapling apparatus
US11596399B2 (en) 2021-06-23 2023-03-07 Covidien Lp Anvil buttress attachment for surgical stapling apparatus
US11510670B1 (en) 2021-06-23 2022-11-29 Covidien Lp Buttress attachment for surgical stapling apparatus
US11672538B2 (en) 2021-06-24 2023-06-13 Covidien Lp Surgical stapling device including a buttress retention assembly
US11678879B2 (en) 2021-07-01 2023-06-20 Covidien Lp Buttress attachment for surgical stapling apparatus
US11684368B2 (en) 2021-07-14 2023-06-27 Covidien Lp Surgical stapling device including a buttress retention assembly
US11801052B2 (en) 2021-08-30 2023-10-31 Covidien Lp Assemblies for surgical stapling instruments
US11751875B2 (en) 2021-10-13 2023-09-12 Coviden Lp Surgical buttress attachment assemblies for surgical stapling apparatus
US11806017B2 (en) 2021-11-23 2023-11-07 Covidien Lp Anvil buttress loading system for surgical stapling apparatus
WO2024015467A1 (en) * 2022-07-12 2024-01-18 Oregon Health & Science University Methods and systems for trans-cervical delivery of agents

Family Cites Families (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3640741A (en) * 1970-02-24 1972-02-08 Hollister Inc Composition containing gel
US3865108A (en) * 1971-05-17 1975-02-11 Ortho Pharma Corp Expandable drug delivery device
US3875939A (en) * 1974-01-31 1975-04-08 Population Res Inc Single stroke dispensing method
YU54174A (en) 1973-03-09 1982-02-28 Population Res Inc Instrument for inserting materials into uterine tubes through the uterine cavity
US3991766A (en) * 1973-05-31 1976-11-16 American Cyanamid Company Controlled release of medicaments using polymers from glycolic acid
US4002173A (en) * 1974-07-23 1977-01-11 International Paper Company Diester crosslinked polyglucan hydrogels and reticulated sponges thereof
DE2437629C3 (en) * 1974-08-05 1978-09-21 Basf Ag, 6700 Ludwigshafen Process for the preparation of insoluble polymers of N-vinyllactams which are only slightly swellable in water
US4014335A (en) * 1975-04-21 1977-03-29 Alza Corporation Ocular drug delivery device
US4207893A (en) * 1977-08-29 1980-06-17 Alza Corporation Device using hydrophilic polymer for delivering drug to biological environment
AT366916B (en) 1980-04-02 1982-05-25 Immuno Ag DEVICE FOR APPLICATING A TISSUE ADHESIVE BASED ON HUMAN OR ANIMAL PROTEINS
US4369229A (en) * 1981-01-29 1983-01-18 The Kendall Company Composite hydrogel-forming article and method of making same
SE445884B (en) * 1982-04-30 1986-07-28 Medinvent Sa DEVICE FOR IMPLANTATION OF A RODFORM PROTECTION
DE3442736A1 (en) * 1984-11-23 1986-06-05 Tassilo Dr.med. 7800 Freiburg Bonzel DILATATION CATHETER
AT382783B (en) 1985-06-20 1987-04-10 Immuno Ag DEVICE FOR APPLICATING A TISSUE ADHESIVE
US4674658A (en) 1985-09-04 1987-06-23 Risdon Corporation Fluid dispenser
US4741872A (en) * 1986-05-16 1988-05-03 The University Of Kentucky Research Foundation Preparation of biodegradable microspheres useful as carriers for macromolecules
US5160745A (en) * 1986-05-16 1992-11-03 The University Of Kentucky Research Foundation Biodegradable microspheres as a carrier for macromolecules
IL82834A (en) * 1987-06-09 1990-11-05 Yissum Res Dev Co Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom
RU2067831C1 (en) * 1987-06-24 1996-10-20 Мицуи Тоацу Кемикалз Инк. Liquid pesticide composition
US4978336A (en) 1987-09-29 1990-12-18 Hemaedics, Inc. Biological syringe system
US5156594A (en) 1990-08-28 1992-10-20 Scimed Life Systems, Inc. Balloon catheter with distal guide wire lumen
US6288561B1 (en) 1988-05-16 2001-09-11 Elm Technology Corporation Method and apparatus for probing, testing, burn-in, repairing and programming of integrated circuits in a closed environment using a single apparatus
US4874368A (en) 1988-07-25 1989-10-17 Micromedics, Inc. Fibrin glue delivery system
US4902281A (en) 1988-08-16 1990-02-20 Corus Medical Corporation Fibrinogen dispensing kit
US5328471A (en) * 1990-02-26 1994-07-12 Endoluminal Therapeutics, Inc. Method and apparatus for treatment of focal disease in hollow tubular organs and other tissue lumens
US4938763B1 (en) * 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5936035A (en) * 1988-11-21 1999-08-10 Cohesion Technologies, Inc. Biocompatible adhesive compositions
US5162430A (en) * 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US5550187A (en) * 1988-11-21 1996-08-27 Collagen Corporation Method of preparing crosslinked biomaterial compositions for use in tissue augmentation
IL90193A (en) * 1989-05-04 1993-02-21 Biomedical Polymers Int Polurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same
US5171148A (en) * 1989-06-30 1992-12-15 Ethicon, Inc. Dental inserts for treatment of periodontal disease
US5116315A (en) 1989-10-03 1992-05-26 Hemaedics, Inc. Biological syringe system
US5198220A (en) * 1989-11-17 1993-03-30 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
EP0454816B1 (en) * 1989-11-21 1994-06-08 GIP Medizintechnik GmbH Injection device
US5067497A (en) * 1990-03-16 1991-11-26 Progressive Medical Design, Inc. Intubation device with adjustable suction means above the cuff
US5634943A (en) * 1990-07-12 1997-06-03 University Of Miami Injectable polyethylene oxide gel implant and method for production
US5391183A (en) 1990-09-21 1995-02-21 Datascope Investment Corp Device and method sealing puncture wounds
US5108421A (en) 1990-10-01 1992-04-28 Quinton Instrument Company Insertion assembly and method of inserting a vessel plug into the body of a patient
US5410016A (en) * 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US6325789B1 (en) 1990-12-27 2001-12-04 Datascope Investment Corporation Device and method for sealing puncture wounds
US5368563A (en) 1991-12-18 1994-11-29 Micromedics, Inc. Sprayer assembly for physiologic glue
US5573934A (en) * 1992-04-20 1996-11-12 Board Of Regents, The University Of Texas System Gels for encapsulation of biological materials
US5280258A (en) 1992-05-22 1994-01-18 Siemens Energy & Automation, Inc. Spring-powered operator for a power circuit breaker
US5476434A (en) * 1992-05-27 1995-12-19 Kalb; Irvin M. Female incontinence device including electronic sensors
US5514379A (en) * 1992-08-07 1996-05-07 The General Hospital Corporation Hydrogel compositions and methods of use
US5469867A (en) * 1992-09-02 1995-11-28 Landec Corporation Cast-in place thermoplastic channel occluder
ATE177613T1 (en) 1992-09-26 1999-04-15 Chemo Sero Therapeut Res Inst TISSUE ADHESIVE APPLICATOR
US5291259A (en) * 1992-11-12 1994-03-01 Eastman Kodak Company Image forming apparatus having toner cleaning device
US5443454A (en) * 1992-12-09 1995-08-22 Terumo Kabushiki Kaisha Catheter for embolectomy
US5290259A (en) 1993-02-18 1994-03-01 Ultradent Products, Inc. Double syringe delivery system
JPH08509642A (en) * 1993-04-28 1996-10-15 フォーカル,インコーポレイテッド Device and method for intraluminal photothermoforming
WO1995008289A2 (en) * 1993-09-16 1995-03-30 Scimed Life Systems, Inc. Percutaneous repair of cardiovascular anomalies and repair compositions
US5522898A (en) * 1993-09-16 1996-06-04 Howmedica Inc. Dehydration of hydrogels
US5437292A (en) * 1993-11-19 1995-08-01 Bioseal, Llc Method for sealing blood vessel puncture sites
US5474540A (en) 1994-03-25 1995-12-12 Micromedics, Inc. Fluid separation control attachment for physiologic glue applicator
JPH0838613A (en) 1994-05-27 1996-02-13 Terumo Corp Operation means of catheter
US5583114A (en) * 1994-07-27 1996-12-10 Minnesota Mining And Manufacturing Company Adhesive sealant composition
US5709934A (en) * 1994-11-22 1998-01-20 Tissue Engineering, Inc. Bipolymer foams having extracellular matrix particulates
EP0713707A1 (en) * 1994-11-23 1996-05-29 Collagen Corporation In situ crosslinkable, injectable collagen composition for tissue augmention
US5605541A (en) 1994-12-07 1997-02-25 E. R. Squibb And Sons, Inc. Fibrin sealant applicatoor
US5810885A (en) 1994-12-28 1998-09-22 Omrix Biopharm Sa Device for applying one or several fluids
US5904665A (en) * 1995-03-07 1999-05-18 Vance Products Inc. Automated prolonged slow release intrauterine insemination using self retaining intrauterine insemination catheter
US5656035A (en) 1995-04-25 1997-08-12 Avoy; Donald R. Refillable fibrinogen dispensing kit
US5785679A (en) * 1995-07-19 1998-07-28 Endotex Interventional Systems, Inc. Methods and apparatus for treating aneurysms and arterio-venous fistulas
EP0842209B1 (en) * 1995-07-28 2006-10-11 Genzyme Corporation Multiblock biodegradable hydrogels for use as controlled release agents for drugs and tissue treatment agents
DE69636325T2 (en) * 1995-09-21 2007-07-26 Sherwood Services Ag Cone-shaped reinforced catheter
US5713854A (en) * 1995-11-01 1998-02-03 Cordis Corporation Method and apparatus for dilatation catheterization
EP0876165B1 (en) 1995-12-18 2006-06-21 Angiotech BioMaterials Corp. Crosslinked polymer compositions and methods for their use
US5752974A (en) * 1995-12-18 1998-05-19 Collagen Corporation Injectable or implantable biomaterials for filling or blocking lumens and voids of the body
JP3727407B2 (en) 1996-04-02 2005-12-14 テルモ株式会社 Catheter tube
US6063061A (en) * 1996-08-27 2000-05-16 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US7009034B2 (en) * 1996-09-23 2006-03-07 Incept, Llc Biocompatible crosslinked polymers
US6371975B2 (en) * 1998-11-06 2002-04-16 Neomend, Inc. Compositions, systems, and methods for creating in situ, chemically cross-linked, mechanical barriers
US6065645A (en) 1997-04-01 2000-05-23 Discus Dental Impressions, Inc. Double-barreled syringe with detachable locking mixing tip
DE19715724C2 (en) * 1997-04-15 1999-10-21 Wilhelm Horkel Device for birth preparation and birth facilitation
AU8913998A (en) * 1997-08-28 1999-03-22 Boston Scientific Corporation System for implanting a cross-linked polysaccharide fiber and methods of formingand inserting the fiber
US6146373A (en) * 1997-10-17 2000-11-14 Micro Therapeutics, Inc. Catheter system and method for injection of a liquid embolic composition and a solidification agent
US6334865B1 (en) 1998-08-04 2002-01-01 Fusion Medical Technologies, Inc. Percutaneous tissue track closure assembly and method
US6514534B1 (en) * 1998-08-14 2003-02-04 Incept Llc Methods for forming regional tissue adherent barriers and drug delivery systems
US6179862B1 (en) * 1998-08-14 2001-01-30 Incept Llc Methods and apparatus for in situ formation of hydrogels
US6632457B1 (en) * 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
US6818018B1 (en) * 1998-08-14 2004-11-16 Incept Llc In situ polymerizable hydrogels
ATE502670T1 (en) 1998-08-14 2011-04-15 Incept Llc APPARATUS FOR IN-SITU FORMATION OF HYDROGELS
US6458147B1 (en) * 1998-11-06 2002-10-01 Neomend, Inc. Compositions, systems, and methods for arresting or controlling bleeding or fluid leakage in body tissue
US6053913A (en) * 1998-09-10 2000-04-25 Tu; Lily Chen Rapid exchange stented balloon catheter having ablation capabilities
WO2000033764A1 (en) * 1998-12-04 2000-06-15 Pathak Chandrashekhar P Biocompatible crosslinked polymers
US6328229B1 (en) 1998-12-18 2001-12-11 Cohesion Technologies, Inc. Low volume mixing spray head for mixing and dispensing of two reactive fluid components
US6312725B1 (en) * 1999-04-16 2001-11-06 Cohesion Technologies, Inc. Rapid gelling biocompatible polymer composition
US6520977B2 (en) * 1999-12-06 2003-02-18 Hadi Piraka Uterine balloon apparatus and method
MXPA00001922A (en) * 2000-02-24 2002-03-08 De Hayos Garza Andres Percutaneous intra-gastric balloon catheter for obesity treatment.

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