CA2334952A1 - Analyzer for determining components in a fluid sample - Google Patents

Analyzer for determining components in a fluid sample Download PDF

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Publication number
CA2334952A1
CA2334952A1 CA002334952A CA2334952A CA2334952A1 CA 2334952 A1 CA2334952 A1 CA 2334952A1 CA 002334952 A CA002334952 A CA 002334952A CA 2334952 A CA2334952 A CA 2334952A CA 2334952 A1 CA2334952 A1 CA 2334952A1
Authority
CA
Canada
Prior art keywords
sample
fluid sample
chip
detector
analyzer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002334952A
Other languages
French (fr)
Other versions
CA2334952C (en
Inventor
Koji Shimoide
Akira Kiguchi
Shigemi Mukaiyama
Hiroshi Kurokawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2334952A1 publication Critical patent/CA2334952A1/en
Application granted granted Critical
Publication of CA2334952C publication Critical patent/CA2334952C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G01N2021/056—Laminated construction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/171—Systems in which incident light is modified in accordance with the properties of the material investigated with calorimetric detection, e.g. with thermal lens detection
    • G01N2021/1712—Thermal lens, mirage effect

Abstract

An analyzer characterized by comprising a chip and a detector, wherein the chip is an organic polymer member having a fine capillary through which a fluid sample or a fluid sample and a fluid reagent flow and can perform a chemical reaction on the sample in the capillary without using a separate weighing means, and the detector is a photothermal conversion detector for measuring a physical quantity change such as a refractive index change caused by a partial temperature change of the sample and the reagent by applying an excitation light to a substance to be measured produced by the chemical reaction, thereby providing a small analyzer excellent in chip waste-disposal, capable of analyzing inexpensively, simply and in a short time and being suitable for a POC analysis.
CA002334952A 1998-06-12 1999-06-14 Analyzer for determining components in a fluid sample Expired - Fee Related CA2334952C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP10/181586 1998-06-12
JP18158698 1998-06-12
PCT/JP1999/003158 WO1999064846A1 (en) 1998-06-12 1999-06-14 Analyzer

Publications (2)

Publication Number Publication Date
CA2334952A1 true CA2334952A1 (en) 1999-12-16
CA2334952C CA2334952C (en) 2006-03-14

Family

ID=16103409

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002334952A Expired - Fee Related CA2334952C (en) 1998-06-12 1999-06-14 Analyzer for determining components in a fluid sample

Country Status (8)

Country Link
US (1) US7105354B1 (en)
EP (1) EP1087223A4 (en)
KR (1) KR20010052741A (en)
CN (1) CN1309769A (en)
AU (1) AU746051B2 (en)
CA (1) CA2334952C (en)
RU (1) RU2195653C2 (en)
WO (1) WO1999064846A1 (en)

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Also Published As

Publication number Publication date
RU2195653C2 (en) 2002-12-27
AU4165899A (en) 1999-12-30
EP1087223A1 (en) 2001-03-28
EP1087223A4 (en) 2004-06-16
US7105354B1 (en) 2006-09-12
KR20010052741A (en) 2001-06-25
CN1309769A (en) 2001-08-22
CA2334952C (en) 2006-03-14
AU746051B2 (en) 2002-04-11
WO1999064846A1 (en) 1999-12-16

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