CA2331694A1 - Ultrasound bandages - Google Patents

Ultrasound bandages Download PDF

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Publication number
CA2331694A1
CA2331694A1 CA002331694A CA2331694A CA2331694A1 CA 2331694 A1 CA2331694 A1 CA 2331694A1 CA 002331694 A CA002331694 A CA 002331694A CA 2331694 A CA2331694 A CA 2331694A CA 2331694 A1 CA2331694 A1 CA 2331694A1
Authority
CA
Canada
Prior art keywords
bandage
ultrasound
substantially coextensive
matching layer
adhesive layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002331694A
Other languages
French (fr)
Other versions
CA2331694C (en
Inventor
Roger J. Talish
Alan A. Winder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Exogen Inc
Original Assignee
Exogen, Inc.
Roger J. Talish
Alan A. Winder
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exogen, Inc., Roger J. Talish, Alan A. Winder filed Critical Exogen, Inc.
Publication of CA2331694A1 publication Critical patent/CA2331694A1/en
Application granted granted Critical
Publication of CA2331694C publication Critical patent/CA2331694C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • G—PHYSICS
    • G10—MUSICAL INSTRUMENTS; ACOUSTICS
    • G10K—SOUND-PRODUCING DEVICES; METHODS OR DEVICES FOR PROTECTING AGAINST, OR FOR DAMPING, NOISE OR OTHER ACOUSTIC WAVES IN GENERAL; ACOUSTICS NOT OTHERWISE PROVIDED FOR
    • G10K11/00—Methods or devices for transmitting, conducting or directing sound in general; Methods or devices for protecting against, or for damping, noise or other acoustic waves in general
    • G10K11/004—Mounting transducers, e.g. provided with mechanical moving or orienting device
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
    • A61H23/02—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
    • A61H23/0245—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive with ultrasonic transducers, e.g. piezoelectric
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0078—Ultrasound therapy with multiple treatment transducers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/42—Piezoelectric device making

Abstract

Ultrasound bandages (10) and ultrasound transducer array bandages are provided herein to accelerate the healing of wounds by positioning the ultrasound bandages (10) and ultrasound transducer array bandages adjacent to a wound and generating ultrasonic pulses. The ultrasound bandages (10) generally include (a) a backing layer (12), (b) an adhesive layer (14) applied to, and substantially coextensive with, the backing layer (12), and (c) a transducer material (16) disposed on at least a portion of the adhesive layer (14). The ultrasound transducer array bandages generally include (a) a backing layer (13), (b) an adhesive layer applied to, and substantially coextensive with, the backing layer, and (c) an array comprising a plurality of transducer materials arranged in adjacent relation to define spaces therebetween, the array being disposed on at least a portion of the adhesive layer. The resulting ultrasound bandages (10) and ultrasound transducer array bandages allows for medical therapeutic applications as promoting the healing of wounds such as abrasions, lacerations, incisions and ulcers at any section or multiple sections of the human anatomy with the ultrasound bandages (10) and ultrasound transducer array bandages being conveniently discarded after each application and a new bandage then being applied for the next application.

Claims (87)

1. An ultrasound bandage which comprises:
a) a backing layer possessing upper and lower surfaces;
b) an adhesive layer applied to, and substantially coextensive with, the lower surface of the backing layer; and, c) a transducer material disposed on at least a portion of the adhesive layer.
2. The ultrasound bandage of Claim 1 wherein the backing layer is a polyurethane film.
3. The ultrasound bandage of Claim 1 wherein the adhesive layer is fabricated from a material selected from the group consisting of polyacrylic resin, polyvinylether resin and polyurethane resin.
4. The ultrasound bandage of Claim 1 wherein the transducer material comprises a fiber sheet formed from a composition containing a piezoelectric material.
5. The ultrasound bandage of Claim 4 wherein the fiber sheet is a fabric woven from one or more fibers containing a piezoelectric material.
6. The ultrasound bandage of Claim 4 wherein the piezoelectric material is selected from the group consisting of PZT powders, ceramic, PVDF, lead zirconate titanate Pb(Zr,Ti)O3, lead metaniobate Pb(Nb2O6), modified lead titanate PbTi3.
(Pb,Ca)TiO3, (Pb,Sm)TiO3, barium titanate BaTiO3, PMN-PT(1-x)Pb(Mg1/3,Nb2/3)O3-xPbTiO3, PZN-PT/BT Pb(Zn1/3,Nb2/3)O3-xPbTiO3-BaTiO3, (1-x)Pb(Zn1/3,Nb2/3)O3-x(yPbTiO3-(1-y)PbZrO3) and mixtures thereof.
7. The ultrasound bandage of Claim 4 wherein the fiber sheet is knitted, braided or woven from extruded fibers containing a piezoelectric material.
8. The ultrasound bandage of Claim 4 wherein the extruded fibers possess a coating formed thereon.
9. The ultrasound bandage of Claim 8 wherein the coating comprises a film-forming polymer solution.
10. The ultrasound bandage of Claim 9 wherein the film-forming polymer solution contains a mixture of a polyvinyl alcohol and polyvinyl acetate as a major component thereof and polyethylene glycol as a minor component thereof.
11. The ultrasound bandage of Claim 1 further comprising an electrode surface applied to, and substantially coextensive with, opposite surfaces of the transducer material and a matching layer applied to, and substantially coextensive with, one of the electrode surfaces.
12. The ultrasound bandage of Claim 11 wherein the matching layer comprises a polymeric material and optionally a filler.
13. The ultrasound bandage of Claim 12 wherein the polymeric material is selected from the group consisting of thermoplastics, thermosets, rubbers, epoxy and mixtures thereof.
14. The ultrasound bandage of Claim 12 wherein the matching layer includes a filler selected from the group consisting of PZT, tungsten, alumina, silica glass, tungsten carbide and titanium.
15. The ultrasound bandage of Claim 12 wherein the matching layer includes glass powder as a filler.
16. The ultrasound bandage of Claim 11 wherein the matching layer has an acoustic impedance of from about 2.0 to about 7.0 MRayls.
17. The ultrasound bandage of Claim 11 further comprising a coupling pad applied to, and substantially coextensive with, the matching layer.
18. The ultrasound bandage of Claim 17 wherein the coupling pad is a hydrogel pad.
19. The ultrasound bandage of Claim 17 wherein the coupling pad is configured as a wedge to direct a longitudinal wave from the transducer material off axis for to an internal designated reflection site and/or for modal conversion.
20. The ultrasound bandage of Claim 1 further comprising connector assemblies having connectors and leads, the connectors detachably connect leads to the transducer material and the leads are coupled to a portable main operating unit.
21. The ultrasound bandage of Claim 19 further comprising a cover covering the adhesive layer and the coupling pad and being applied to the adhesive layer.
22. A method for manufacturing an ultrasound bandage which comprises:
a) providing a backing layer possessing upper and lower surfaces;
b) applying an adhesive layer to, and substantially coextensive with, the lower surface of the backing layer; and, c) disposing a transducer material on at least a portion of the adhesive layer.
23. The method of Claim 22 wherein the backing layer is a polyurethane film.
24. The method of Claim 22 wherein the adhesive layer is fabricated from a material selected from the group consisting of polyacrylic resin, polyvinylether resin and polyurethane resin.
25. The method of Claim 22 wherein the transducer material comprises a fiber sheet formed from a composition containing a piezoelectric material.
26. The method of Claim 25 wherein the fiber sheet is a fabric woven from one or more fibers containing a piezoelectric material.
27. The method of Claim 25 wherein the piezoelectric material is selected from the group consisting of PZT powders, ceramic, PVDF, lead zirconate titanate Pb(Zr,Ti)O3, lead metaniobate Pb(Nb2O6), modified lead titanate PbTi3, (Pb,Ca)TiO3, (Pb,Sm)TiO3, barium titanate BaTiO3, PMN-PT(1-x)Pb(Mg1/3,Nb2/3)O3-xPbTiO3, PZN-PT/BT Pb(Zn1/2,Nb2/3)O3-xPbTiO3-BaTiO3, (1-x)Pb(Zn1/2,Nb2/3)O3-x(yPbTiO3-(1-y)PbZrO3) and mixtures thereof.
28. The method of Claim 25 wherein the extruded fibers possess a coating formed thereon.
29. The method of Claim 28 wherein the coating comprises a film-forming polymer solution.
30. The method of Claim 29 wherein the film-forming polymer solution contains a mixture of a polyvinyl alcohol and polyvinyl acetate as a major component thereof and polyethylene glycol as a minor component thereof.
31. The method of Claim 22 further comprising an electrode surface applied to, and substantially coextensive with, opposite surfaces of the transducer material and a matching layer applied to, and substantially coextensive with, one of the electrode surfaces.
32. The method of Claim 31 wherein the matching layer comprises a polymeric material and optionally a filler.
33. The method of Claim 32 wherein the polymeric material is selected from the group consisting of thermoplastics, thermosets, rubbers, epoxy and mixtures thereof.
34. The method of Claim 32 wherein the matching layer includes a filler selected from the group consisting of PZT, tungsten, alumina, silica glass, tungsten carbide and titanium.
35. The method of Claim 32 wherein the matching layer includes glass powder as a filler.
36. The method of Claim 31 wherein the matching layer has an acoustic impedance of from about 2.0 to about 7.0 MRayls.
37. The method of Claim 31 further comprising applying a coupling pad to, and substantially coextensive with, the matching layer.
38. The method of Claim 37 wherein the coupling pad is a hydrogel pad.
39. The method of Claim 37 wherein the coupling pad is configured as a wedge to direct a longitudinal wave from the transducer material off-axis for to an internal designated reflection site and/or for modal conversion.
40. The method of Claim 22 further comprising connecting connector assemblies having connectors and leads to the transducer material of the ultrasonic bandage.
41. An ultrasound transducer array bandage which comprises:
a) a backing layer possessing upper and lower surfaces;
b) an adhesive layer applied to, and substantially coextensive with, the lower surface of the backing layer;
c) an array comprising a plurality of transducer materials arranged in adjacent relation to define spaces therebetween, the array being disposed on at least a portion of the adhesive layer; and, d) a connector assembly applied to the array.
42. The ultrasound transducer array bandage of Claim 41 wherein the backing layer is a polyurethane film.
43. The ultrasound transducer array bandage of Claim 41 wherein the adhesive layer is fabricated from a material selected from the group consisting of polyacrylic resin, polyvinylether resin and polyurethane resin.
44. The ultrasound transducer array bandage of Claim 41 wherein each transducer material comprises a fiber sheet formed from a composition containing a piezoelectric material.
45. The ultrasound transducer array bandage of Claim 44 wherein the fiber sheet is a fabric woven from one or more extruded fibers containing a piezoelectric material.
46. The ultrasound transducer array bandage of Claim 44 wherein the piezoelectric material is selected from the group consisting of PZT powders, ceramic, PVDF, lead zirconate titanate Pb(Zr,Ti)O3, lead metaniobate Pb(Nb2O6), modified lead titanate PbTi3, (Pb,Ca)TiO3, (Pb,Sm)TiO3, barium titanate BaTiO3, PMN-PT(1-x)Pb(Mg1/3,Nb2/3)O3-xPbTiO3, PZN-PT/BT Pb(Zn1/2,Nb2/3)O3-xPbTiO3 BaTiO3, (1-x)Pb(Zn1/3,Nb2/3)O3-x(yPbTiO3-(1-y)PbZrO3) and mixtures thereof.
47. The ultrasound transducer array bandage of Claim 44 wherein the fiber sheet is knitted, braided or woven from extruded fibers containing a piezoelectric material.
48. The ultrasound transducer array bandage of Claim 44 wherein the extruded fibers possess a coating formed thereon.
49. The ultrasound transducer array bandage of Claim 48 wherein the coating comprises a film-forming polymer solution.
50. The ultrasound transducer array bandage of Claim 49 wherein the film-forming polymer solution contains a mixture of a polyvinyl alcohol and polyvinyl acetate as a major component thereof and polyethylene glycol as a minor component thereof.
51. The ultrasound transducer array bandage of Claim 41 further comprising an electrode surface applied to, and substantially coextensive with, opposite surfaces of each transducer material and a matching layer applied to, and substantially coextensive with, one of the electrode surfaces.
52. The ultrasound transducer array bandage of Claim 51 wherein the matching layer comprises a polymeric material and optionally a filler.
53. The ultrasound transducer array bandage of Claim 52 wherein the polymeric material is selected from the group consisting of thermoplastics, thermosets, rubbers, epoxy and mixtures thereof.
54. The ultrasound transducer array bandage of Claim 52 wherein the matching layer includes a filler selected from the group consisting of PZT, tungsten, alumina, silica glass, tungsten carbide and titanium.
55. The ultrasound transducer array bandage of Claim 52 wherein the matching layer includes glass powder as a filler.
56. The ultrasound bandage of Claim 51 wherein the matching layer has an acoustic impedance of from about 2.0 to about 7.0 MRayls.
57. The ultrasound transducer array bandage of Claim 51 further comprising a coupling pad applied to, and substantially coextensive with, the matching layer.
58. The ultrasound transducer array bandage of Claim 57 wherein the coupling pad is a hydrogel pad.
59. The ultrasound transducer array bandage of Claim 57 wherein the coupling pad is configured as a wedge to direct a longitudinal wave from each transducer material off axis for to an internal designated reflection site and/or for modal conversion.
60. The ultrasound transducer array bandage of Claim 41 wherein the connector assemblies comprise connectors and leads, the connectors detachably connect leads to the array and the leads are coupled to a portable main operating unit.
61. The ultrasound transducer array bandage of Claim 41 further comprising a cover covering the adhesive layer and the coupling pad and being applied to the adhesive layer.
62. A method for manufacturing an ultrasound transducer array bandage which comprises:
a) providing a backing layer possessing upper and lower surfaces;
b) applying an adhesive layer to, and substantially coextensive with, the lower surface of the backing layer;
c) disposing an array comprising a plurality of transducer materials arranged in adjacent relation to define spaces therebetween on at least a portion of the adhesive layer; and, d) applying a connector assembly to the array.
63. The method of Claim 62 wherein the backing layer is a polyurethane film.
64. The method of Claim 62 wherein the adhesive layer is fabricated from a material selected from the group consisting of polyacrylic resin, polyvinylether resin and polyurethane resin.
65. The method of Claim 62 wherein each transducer material comprises a fiber sheet formed from a composition containing a piezoelectric material.
66. The method of Claim 65 wherein the piezoelectric material is selected from the group consisting of PZT powders, ceramic, PVDF, lead zirconate titanate Pb(Zr,Ti)O3, lead metaniobate Pb(N22O6), modified lead titanate PbTi3, (Pb,Ca)TiO3, (Pb,Sm)TiO3, barium titanate BaTiO3, PMN-PT(1-x)Pb(Mg1/3,Nb2/3)O3-xPbTiO3, PZN-PT/BT Pb(Zn1/3,Nb2/3)O3-xPbTiO3-BaTiO3, (1-x)Pb(Zn1/3,Nb2/3)O3-x(yPbTiO3-(1-y)PbZrO3) and mixtures thereof.
67. The method of Claim 65 wherein the fiber sheet is a fabric woven from one or more fibers containing a piezoelectric material.
68. The method of Claim 65 further comprising the step of forming the fiber sheet by knitting, braiding or weaving the extruded fibers.
69. The method of Claim 68 further comprising applying a coating to the extruded fibers prior to forming the fiber sheet.
70. The method of Claim 69 wherein the coating comprises a film-forming polymer solution.
71. The method of Claim 70 wherein the film-forming polymer solution contains a mixture of a polyvinyl alcohol and polyvinyl acetate as a major component thereof and polyethylene glycol as a minor component thereof.
72. The method of Claim 62 further comprising an electrode surface applied to, and substantially coextensive with, opposite surfaces of each transducer material and a matching layer applied to, and substantially coextensive with, one of the electrode surfaces.
73. The method of Claim 72 wherein the matching layer comprises a polymeric material and optionally a filler.
74. The method of Claim 73 wherein the polymeric material is selected from the group consisting of thermoplastics, thermosets, rubbers, epoxy and mixtures thereof.
75. The method of Claim 73 wherein the matching layer includes a filler selected from the group consisting of PZT, tungsten, alumina, silica glass, tungsten carbide and titanium.
76. The method of Claim 73 wherein the matching layer includes glass powder as a filler.
77. The ultrasound bandage of Claim 72 wherein the matching layer has an acoustic impedance of from about 2.0 to about 7.0 MRayls.
78. The method of Claim 72 further comprising applying a coupling pad to, and substantially coextensive with, the matching layer
79. The method of Claim 78 wherein the coupling pad is a hydrogel pad.
80. The method of Claim 78 wherein the coupling pad is configured as a wedge to direct a longitudinal wave from each transducer material off-axis for to an internal designated reflection site and/or for modal conversion.
81. The method of Claim 62 wherein the connector assemblies comprise connectors and leads.
82. A method for accelerating the healing of wounds comprising:
a) positioning at least one ultrasound bandage adjacent to a body at the site of a wound;
b) the ultrasound bandage comprising:
I) a backing layer possessing upper and lower surfaces;
ii) an adhesive layer applied to, and substantially coextensive with, the lower surface of the backing layer; and, iii) a transducer material disposed on at least a portion of the adhesive layer; and, c) causing the transducer material to generate ultrasonic pulses.
83. The method of Claim 82 wherein at least one ultrasound bandage is positioned adjacent to a body at a plurality of sites of wounds.
84. The method of Claim 82 further comprising applying an electrode surface to, and substantially coextensive with, opposite surfaces of the transducer material, applying a matching layer to, and substantially coextensive with, one of the electrode surfaces and applying a coupling pad configured as a wedge to the matching layer.
85. A method for accelerating the healing of wounds comprising:
a) positioning at least one ultrasound transducer array bandage adjacent to a body at the site of a wound;
b) the ultrasound transducer array bandage comprising:
I) a backing layer possessing upper and lower surfaces;

ii) an adhesive layer applied to, and substantially coextensive with, the lower surface of the backing layer; and, iii) an array comprising a plurality of transducer materials arranged in adjacent relation to define spaces therebetween, the array being disposed on at least a portion of the adhesive layer and, c) causing the plurality transducer materials to generate ultrasonic pulses.
86. The method of Claim 85 wherein at least one ultrasound transducer array bandage is positioned adjacent to a body at a plurality of sites of wounds.
87. The method of Claim 85 further comprising applying an electrode surface to, and substantially coextensive with, opposite surfaces of each transducer material, applying a matching layer to, and substantially coextensive with, one of the electrode surfaces and applying a coupling pad configured as a wedge to the matching layer.
CA2331694A 1998-05-06 1999-05-06 Ultrasound bandages Expired - Fee Related CA2331694C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8445398P 1998-05-06 1998-05-06
US60/084,453 1998-05-06
PCT/US1999/009875 WO1999056829A1 (en) 1998-05-06 1999-05-06 Ultrasound bandages

Publications (2)

Publication Number Publication Date
CA2331694A1 true CA2331694A1 (en) 1999-11-11
CA2331694C CA2331694C (en) 2011-07-05

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA2331694A Expired - Fee Related CA2331694C (en) 1998-05-06 1999-05-06 Ultrasound bandages

Country Status (11)

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US (2) US7211060B1 (en)
EP (1) EP1076586B1 (en)
JP (1) JP2002513661A (en)
AT (1) ATE342102T1 (en)
AU (1) AU763551B2 (en)
CA (1) CA2331694C (en)
DE (1) DE69933555T2 (en)
ES (1) ES2274626T3 (en)
MX (1) MXPA00010847A (en)
PT (1) PT1076586E (en)
WO (1) WO1999056829A1 (en)

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WO1999056829A1 (en) 1999-11-11
ES2274626T3 (en) 2007-05-16
EP1076586A1 (en) 2001-02-21
MXPA00010847A (en) 2002-05-08
EP1076586B1 (en) 2006-10-11
CA2331694C (en) 2011-07-05
JP2002513661A (en) 2002-05-14
US7211060B1 (en) 2007-05-01
US20070208280A1 (en) 2007-09-06
ATE342102T1 (en) 2006-11-15
DE69933555D1 (en) 2006-11-23
DE69933555T2 (en) 2007-06-14
PT1076586E (en) 2007-01-31
AU3972199A (en) 1999-11-23
AU763551B2 (en) 2003-07-24
WO1999056829A8 (en) 2000-01-13

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