CA2321739A1 - Random access slide stainer with liquid waste segregation - Google Patents

Random access slide stainer with liquid waste segregation Download PDF

Info

Publication number
CA2321739A1
CA2321739A1 CA002321739A CA2321739A CA2321739A1 CA 2321739 A1 CA2321739 A1 CA 2321739A1 CA 002321739 A CA002321739 A CA 002321739A CA 2321739 A CA2321739 A CA 2321739A CA 2321739 A1 CA2321739 A1 CA 2321739A1
Authority
CA
Canada
Prior art keywords
liquid waste
aspiration head
liquid
waste collection
aspiration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002321739A
Other languages
French (fr)
Other versions
CA2321739C (en
Inventor
Steven A. Bogen
Herbert H. Loeffler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dako Denmark ApS
Original Assignee
Cytologix Corporation
Steven A. Bogen
Herbert H. Loeffler
Dako Denmark A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytologix Corporation, Steven A. Bogen, Herbert H. Loeffler, Dako Denmark A/S filed Critical Cytologix Corporation
Publication of CA2321739A1 publication Critical patent/CA2321739A1/en
Application granted granted Critical
Publication of CA2321739C publication Critical patent/CA2321739C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N2001/317—Apparatus therefor spraying liquids onto surfaces

Abstract

An automated slide stainer with slides mounted in a horizontal position on a rotary carousel. Reagents and rinse liquids are automatically dispensed onto tissue sections or cells mounted on slides for the purpose of performing chemical or immunohistochemical stains. The rinse liquids are removed by an aspiration head (31) connected to a source of vacuum. The aspiration head (31) is a hollow chamber (40) with a flattened bottom aspect. Eight holes (41) in the bottom of the aspiration head provide for fluid communication between the exterior and interior of the aspiration head. To aspirate liquid off of a slide, the aspiration head is lowered so that the bottom aspect contacts the liquid. The liquid is sucked into the hollow interior (40) of the aspiration head and collected into a liquid waste collection bottle. Several different liquid waste collection bottles (59) are placed in parallel, between the source of vacuum and the aspiration head.
A solenoid valve (80) is positioned in line with each liquid waste collection bottle. Depending upon which solenoid valve is opened, the operator can direct the liquid waste to be collected into a specified liquid waste collection bottle.
CA002321739A 1998-02-27 1999-02-25 Random access slide stainer with liquid waste segregation Expired - Lifetime CA2321739C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/032,680 US6096271A (en) 1998-02-27 1998-02-27 Random access slide stainer with liquid waste segregation
US09/032,680 1998-02-27
PCT/US1999/004093 WO1999044031A1 (en) 1998-02-27 1999-02-25 Random access slide stainer with liquid waste segregation

Publications (2)

Publication Number Publication Date
CA2321739A1 true CA2321739A1 (en) 1999-09-02
CA2321739C CA2321739C (en) 2008-12-16

Family

ID=21866251

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002321739A Expired - Lifetime CA2321739C (en) 1998-02-27 1999-02-25 Random access slide stainer with liquid waste segregation

Country Status (9)

Country Link
US (1) US6096271A (en)
EP (2) EP1398613B1 (en)
JP (1) JP4309577B2 (en)
AT (2) ATE326691T1 (en)
AU (1) AU2789199A (en)
CA (1) CA2321739C (en)
DE (2) DE69931408T2 (en)
ES (2) ES2212534T3 (en)
WO (1) WO1999044031A1 (en)

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Also Published As

Publication number Publication date
DE69913947T2 (en) 2004-12-09
ATE326691T1 (en) 2006-06-15
ES2263912T3 (en) 2006-12-16
US6096271A (en) 2000-08-01
EP1058826A1 (en) 2000-12-13
ATE257245T1 (en) 2004-01-15
ES2212534T3 (en) 2004-07-16
WO1999044031A1 (en) 1999-09-02
AU2789199A (en) 1999-09-15
DE69913947D1 (en) 2004-02-05
JP2002505419A (en) 2002-02-19
EP1058826B1 (en) 2004-01-02
DE69931408T2 (en) 2007-04-19
JP4309577B2 (en) 2009-08-05
EP1398613A2 (en) 2004-03-17
DE69931408D1 (en) 2006-06-22
EP1398613B1 (en) 2006-05-17
EP1398613A3 (en) 2004-03-31
CA2321739C (en) 2008-12-16

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EEER Examination request
MKEX Expiry

Effective date: 20190225