CA2310616A1 - Method and apparatus for preserving human saliva for testing - Google Patents

Method and apparatus for preserving human saliva for testing Download PDF

Info

Publication number
CA2310616A1
CA2310616A1 CA002310616A CA2310616A CA2310616A1 CA 2310616 A1 CA2310616 A1 CA 2310616A1 CA 002310616 A CA002310616 A CA 002310616A CA 2310616 A CA2310616 A CA 2310616A CA 2310616 A1 CA2310616 A1 CA 2310616A1
Authority
CA
Canada
Prior art keywords
testing
human saliva
saliva sample
specimen cup
preserving human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002310616A
Other languages
French (fr)
Other versions
CA2310616C (en
Inventor
David R. Schneider
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2310616A1 publication Critical patent/CA2310616A1/en
Application granted granted Critical
Publication of CA2310616C publication Critical patent/CA2310616C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A61B10/0051—Devices for taking samples of body liquids for taking saliva or sputum samples
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0672—Swellable plugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • B01L2400/0683—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber

Abstract

A method and apparatus for the preservation of a saliva sample for use in subsequent quantitative chemical assays. The method involves collecting a saliva sample at a location, directly into a specimen cup. The specimen cup contains a predetermined volume of aqueous solution of pH buffered saline and enzymatic inhibitor and is optionally adapted with a constituent compound specific, qualitative test unit.
CA002310616A 1997-11-26 1998-11-24 Method and apparatus for preserving human saliva for testing Expired - Fee Related CA2310616C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/978,729 US5968746A (en) 1997-11-26 1997-11-26 Method and apparatus for preserving human saliva for testing
US08/978,729 1997-11-26
PCT/US1998/025089 WO1999027139A1 (en) 1997-11-26 1998-11-24 Method and apparatus for preserving human saliva for testing

Publications (2)

Publication Number Publication Date
CA2310616A1 true CA2310616A1 (en) 1999-06-03
CA2310616C CA2310616C (en) 2009-02-03

Family

ID=25526342

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002310616A Expired - Fee Related CA2310616C (en) 1997-11-26 1998-11-24 Method and apparatus for preserving human saliva for testing

Country Status (9)

Country Link
US (2) US5968746A (en)
EP (1) EP1032709B1 (en)
JP (1) JP2001524321A (en)
AT (1) ATE397891T1 (en)
AU (1) AU754598B2 (en)
CA (1) CA2310616C (en)
DE (1) DE69839613D1 (en)
NZ (1) NZ505342A (en)
WO (1) WO1999027139A1 (en)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7569342B2 (en) 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
WO2000055635A1 (en) * 1999-03-16 2000-09-21 Serex Inc. Method and device for detection of apo a, apo b and the ratio thereof in saliva
US6489172B1 (en) * 2000-01-05 2002-12-03 Varian, Inc. Saliva sampling device
US6699722B2 (en) 2000-04-14 2004-03-02 A-Fem Medical Corporation Positive detection lateral-flow apparatus and method for small and large analytes
US6623698B2 (en) 2001-03-12 2003-09-23 Youti Kuo Saliva-monitoring biosensor electrical toothbrush
US6663831B2 (en) 2001-04-04 2003-12-16 Forefront Diagnostics, Inc. “One-device” system for testing constituents in fluids
US7879293B2 (en) * 2001-09-28 2011-02-01 Orasure Technologies, Inc. Sample collector and test device
US20030073241A1 (en) * 2001-10-11 2003-04-17 Genacy System, method, and apparatus for disease susceptibility testing
US6907879B2 (en) 2002-02-04 2005-06-21 Ndt Agent delivery and aspiration device
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
US20040087874A1 (en) * 2002-10-28 2004-05-06 David Schneider Saliva collection system
US7560272B2 (en) 2003-01-04 2009-07-14 Inverness Medical Switzerland Gmbh Specimen collection and assay container
EP1616035A4 (en) 2003-04-01 2007-02-21 Univ Southern California Caries risk test for predicting and assessing the risk of disease
US7114403B2 (en) * 2003-05-30 2006-10-03 Oakville Hong Kong Co., Ltd Fluid collection and application device and methods of use of same
WO2005008216A2 (en) * 2003-07-11 2005-01-27 Oakville Hong Kong Co., Limited Sanitary fluid collection, application and storage device and methods of use of same
NZ547174A (en) 2003-11-14 2009-09-25 Inverness Medical Switzerland Rapid sample collection and analysis device and methods of use
EP1687620B1 (en) * 2003-11-14 2014-04-23 Alere Switzerland GmbH Sample collection cup with integrated sample analysis system
DE212004000058U1 (en) * 2003-11-14 2006-09-28 Oakville Hong Kong Co., Ltd. Sample collection container with integrated activatable sample analysis system
AT500882A3 (en) * 2004-10-06 2009-12-15 Greiner Bio One Gmbh IN-VITRO DIAGNOSTICS FOR STORAGE VOLUME DETERMINATION
US20060199269A1 (en) * 2005-03-07 2006-09-07 Schneider David R Method for assessing pyrimidine metabolism
CA2600758C (en) * 2005-03-16 2016-01-12 Dna Genotek Inc. Compositions and method for storage of nucleic acid from bodily fluids
US20070031293A1 (en) * 2005-08-04 2007-02-08 Beatty Christopher C Method and apparatus for collecting and diluting a liquid sample
CN100478671C (en) * 2005-10-25 2009-04-15 艾康生物技术(杭州)有限公司 Detector and method for liquid sampler
CN101326443B (en) 2005-11-30 2012-05-30 阿莱瑞士股份有限公司 Apparatus and method for detecting analysis article in fluid sample
JP5150507B2 (en) * 2005-12-09 2013-02-20 ディーエヌエー ジェノテック インク Container system for storing substances so that they can be released
AU2007280929B2 (en) 2006-07-26 2012-03-22 Abbott Rapid Diagnostics International Unlimited Company Analysis device for biological sample
US20080306362A1 (en) * 2007-06-05 2008-12-11 Owen Davis Device and system for monitoring contents of perspiration
US20100323441A1 (en) * 2007-12-13 2010-12-23 Biocell Center S.P.A. Method of collection and preservation of fluids and/or materials, in particular of organic fluids and/or materials containing stem cells, and device employable in such method
GB0725234D0 (en) * 2007-12-24 2008-02-06 Oxtex Ltd Electrochemical assays
US20110050407A1 (en) * 2007-12-27 2011-03-03 Alexander Schoenfeld Sobriety interlock device
CN101881735B (en) * 2010-06-11 2011-11-16 赵永秀 Method for detecting paraquat in urine
US20120168024A1 (en) * 2010-12-29 2012-07-05 Robin Beck Breath Containment Keepsake Item and Method
CN106442039B (en) 2011-06-19 2020-08-07 阿博根公司 Device, solution and method for sample collection
WO2013123151A1 (en) * 2012-02-14 2013-08-22 The Wistar Institute Of Anatomy And Biology Methods of controlling tumor bioenergetics networks
CN102768277B (en) * 2012-07-25 2014-05-07 成都协和生物技术有限责任公司 Sample diluent of oral mucosal transudate for detecting HIV antibody by colloidal gold method, and preparation method thereof
CA2885845C (en) 2012-11-07 2019-10-29 Sandstone Diagnostics, Inc. Methods and devices for processing samples and counting cells
US10197480B2 (en) 2012-11-07 2019-02-05 Sandstone Diagnostics, Inc. Methods and devices for processing samples and counting cells
WO2014124179A1 (en) 2013-02-07 2014-08-14 Sandstone Diagnostics, Inc. Automated sample processing, fluid distribution, and sedimentation assay
US10073069B2 (en) 2013-04-23 2018-09-11 Cordant Research Solutions, Llc Systems and methods to determine body drug concentration from an oral fluid
CN106574929B (en) * 2014-07-25 2019-08-09 贝克顿·迪金森公司 Analyte testing item test and for its implement test-strips and kit
US20180031543A1 (en) * 2015-02-09 2018-02-01 Abogen, Inc. Devices, solutions and methods for sample collection related applications, analysis and diagnosis
US20170350797A1 (en) * 2016-06-06 2017-12-07 Preston Estep Sample collection and DNA preservation device
WO2018217184A1 (en) 2017-05-20 2018-11-29 Sandstone Diagnostics, Inc. Specimen cup
CN107266561B (en) * 2017-08-01 2020-08-07 浙江理工大学 Preparation method of cotton cellulose enzymatic hydrolysate coupled protein for cultural relic detection
USD867611S1 (en) 2018-01-29 2019-11-19 Sandstone Diagnostics, Inc. Sample cup
EP3884070A4 (en) 2018-11-20 2022-09-07 Spectrum Solutions, LLC Sample collection system including sealing cap and valve
US20200391203A1 (en) * 2019-06-13 2020-12-17 Roger Wallace Giese Low-alcohol jar for serial saliva and breath metabolomics
US11701094B2 (en) 2019-06-20 2023-07-18 Spectrum Solutions L.L.C. Sample collection system including valve and plug assemblies
JPWO2022113150A1 (en) * 2020-11-24 2022-06-02
CN114588956B (en) * 2020-12-03 2023-06-16 中国科学院大连化学物理研究所 Microfluidic chip glutathione local hydrophilic modification method based on laminar flow effect
CN112640885B (en) * 2020-12-08 2022-04-12 河北工程大学 Room temperature preservation method of fatigue human saliva sample
CN114368498B (en) * 2021-06-15 2023-04-04 百康芯(天津)生物科技有限公司 Production processing treatment process of disposable virus sampling tube
CN113966737B (en) * 2021-11-17 2022-10-04 深圳市华晨阳科技有限公司 Cell preservation solution for in-vitro analysis and detection and preparation method thereof

Family Cites Families (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2591927A (en) * 1948-10-06 1952-04-08 Sidney A Gladstone Obtaining tumor tissue specimen
US3542025A (en) * 1968-05-29 1970-11-24 Fuller Lab Inc Surgical type scrubbing sponge
US4063558A (en) * 1975-11-07 1977-12-20 Avtex Fibers Inc. Article and method for making high fluid-holding fiber mass
US4114605A (en) * 1976-11-02 1978-09-19 University Of Alabama In Birmingham Intraoral cup for collecting saliva and method of using the same
US4232552A (en) * 1978-09-28 1980-11-11 Akzona Incorporated Temperature indicating compositions of matter
US4339207A (en) * 1978-09-28 1982-07-13 Akzona Incorporated Temperature indicating compositions of matter
US4362645A (en) * 1978-09-28 1982-12-07 Akzona, Inc. Temperature indicating compositions of matter
US4292978A (en) * 1979-12-26 1981-10-06 Guth Richard U Breath test mouthpiece
US4418702A (en) * 1981-01-12 1983-12-06 Metpath Inc. Method and apparatus for collecting saliva
US4580577A (en) * 1981-01-12 1986-04-08 Brien Joseph O Method and apparatus for collecting saliva
JPS58225029A (en) * 1982-06-21 1983-12-27 Showa Yakuhin Kako Kk Simple diagnostic method for tooth decay and device therefor
GB8306353D0 (en) * 1983-03-08 1983-04-13 Stuart J F B Monitoring of drug levels
US4734360A (en) * 1983-07-12 1988-03-29 Lifescan, Inc. Colorimetric ethanol analysis method and test device
US4900666A (en) * 1983-07-12 1990-02-13 Lifescan, Inc. Colorimetric ethanol analysis method and test device
US4642286A (en) * 1984-05-07 1987-02-10 Moldowan Mervin J Composition and method for ethanol determination
US4810633A (en) * 1984-06-04 1989-03-07 Miles Inc. Enzymatic ethanol test
US4635488A (en) * 1984-12-03 1987-01-13 Schleicher & Schuell, Inc. Nonintrusive body fluid samplers and methods of using same
US4692407A (en) * 1985-01-31 1987-09-08 Forsyth Dental Infirmary For Children Method for the determination of Streptococcus mutans
US4786596A (en) * 1985-02-20 1988-11-22 Chem-Elec., Inc. Method of preparing a test strip for alcohol testing
DE3632303C2 (en) * 1985-09-23 1995-04-13 Sarstedt Kunststoff Method of extracting human saliva
US4839296A (en) * 1985-10-18 1989-06-13 Chem-Elec, Inc. Blood plasma test method
US4705514A (en) * 1986-01-22 1987-11-10 Barnhardt Manufacturing Corporation Absorbent dental roll
US4853325A (en) * 1986-03-26 1989-08-01 Synbiotics Corporation Saliva test for feline leukemia virus
US4740475A (en) * 1986-03-28 1988-04-26 Medi-Scan, Inc. Integral substance detection device and method
US4935346A (en) * 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
US4800083A (en) * 1986-10-20 1989-01-24 R. P. Scherer Corporation Sustained release method and product
US4770853A (en) 1986-12-03 1988-09-13 New Horizons Diagnostics Corporation Device for self contained solid phase immunodiffusion assay
KR900005223B1 (en) * 1986-12-11 1990-07-21 가부시끼가이샤 호리바 세이사꾸쇼 Method of measuring ion-concentration and the like and a calibrating sheet as well as a calibrating method of measuring device used therein
US5032506A (en) * 1986-12-16 1991-07-16 Enzymatics, Inc. Color control system
US5036000A (en) * 1986-12-16 1991-07-30 Enzymatics, Inc. Threshold color control system
US4999613A (en) * 1987-04-21 1991-03-12 Guardian Technologies, Inc. Remote confinement system
US4843377A (en) * 1987-04-21 1989-06-27 Guardian Technologies, Inc. Remote confinement system
US4997771A (en) * 1987-04-27 1991-03-05 Schering Corporation Method for measuring the BZ-1 receptor binding activity in a test sample or test compound
US4817632A (en) 1987-06-23 1989-04-04 Bioquant, Inc. Oral fluid collection article
US5447837A (en) * 1987-08-05 1995-09-05 Calypte, Inc. Multi-immunoassay diagnostic system for antigens or antibodies or both
US5149623A (en) * 1988-02-09 1992-09-22 Virotest, Inc. Rapid, easy, and economical screening test for antibodies to human immunodeficiency virus
US5126247A (en) * 1988-02-26 1992-06-30 Enzymatics, Inc. Method, system and devices for the assay and detection of biochemical molecules
US5232914A (en) * 1988-04-11 1993-08-03 Epitope, Inc. Solid, storage-stable, germicidal, pre-iodine composition
US5112758A (en) * 1988-05-09 1992-05-12 Epitope, Inc. Treating body fluids for diagnostic testing
US4916435A (en) * 1988-05-10 1990-04-10 Guardian Technologies, Inc. Remote confinement monitoring station and system incorporating same
US5112741A (en) * 1988-07-07 1992-05-12 Enzymatics, Inc. Acetaldehyde trapping system
US4925629A (en) 1988-07-28 1990-05-15 Bioquant, Inc. Diagnostic device
US5017471A (en) * 1988-08-26 1991-05-21 Epitope, Inc. Reagent for peroxidase detection
US5248791A (en) * 1989-04-10 1993-09-28 Abbott Laboratories Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay
US5101015A (en) * 1989-04-10 1992-03-31 Abbott Laboratories Reagents for an amphetamine-class fluorescence polarization immunoassay
US5479937A (en) * 1989-09-21 1996-01-02 Epitope, Inc. Oral collection device
US5103836A (en) * 1990-02-28 1992-04-14 Epitope, Inc. Oral collection device and kit for immunoassay
US5022409A (en) * 1989-09-21 1991-06-11 Epitope, Inc. Oral rinse immunoglobulin collection kit for immunoassay and method thereof
US5335673A (en) * 1989-09-21 1994-08-09 Epitope, Inc. Oral collection device and method for immunoassay
US5339829A (en) * 1989-09-21 1994-08-23 Epitope, Inc. Oral collection device
US5244815A (en) * 1990-01-19 1993-09-14 Lamina Ltd. Fingerprint test pad and method for fingerprinting using particle based immunoassay
GB9002274D0 (en) * 1990-02-01 1990-03-28 Cranfield Biotech Ltd Colorimetric analysis
US5091153A (en) * 1990-10-11 1992-02-25 Toxi-Lab Incorporated Chemical analysis test device
US5173433A (en) * 1990-10-11 1992-12-22 Toxi-Lab Incorporated Method for chemical analysis
JPH06102605B2 (en) * 1990-11-19 1994-12-14 昭和薬品化工株式会社 Dental test agent composition
US5141854A (en) * 1990-12-13 1992-08-25 Hoffman-La Roche, Inc. Enzymatic composition for ethanol assay
US5393496A (en) * 1990-12-18 1995-02-28 Saliva Diagnostic Systems, Inc. Saliva sampling device and sample adequacy system
US5268148A (en) * 1990-12-18 1993-12-07 Saliva Diagnostic Systems, Inc. Saliva sampling device and sample adequacy system
US5283038A (en) 1990-12-18 1994-02-01 Saliva Diagnostic Systems, Inc. Fluid sampling and testing device
GB9118913D0 (en) * 1991-09-04 1991-10-23 Lion Lab Plc Method and apparatus for determining the concentration of components of liquid systems
US5179288A (en) * 1991-09-30 1993-01-12 Ortho Pharmaceutical Corporation Apparatus and method for measuring a bodily constituent
US5211182A (en) * 1991-10-23 1993-05-18 Deutsch Marshall E Home ovulation test kit and method
US5334502A (en) * 1991-11-27 1994-08-02 Osborn Laboratories, Inc. Method of collecting, identifying, and quantifying saliva
US5278079A (en) * 1992-09-02 1994-01-11 Enzymatics, Inc. Sealing device and method for inhibition of flow in capillary measuring devices
US5290683A (en) * 1992-11-19 1994-03-01 Yedy Israel Rapid analysis of ethanol in body fluids
KR970001146B1 (en) * 1993-07-16 1997-01-29 엘지전자 주식회사 Gas measuring bio-sensor and manufacturing method
US5563073A (en) * 1993-08-31 1996-10-08 Titmas; Ted Personal blood alcohol level testing kit
KR970010981B1 (en) * 1993-11-04 1997-07-05 엘지전자 주식회사 Alcohol concentration measuring bio-sensor, manufacturing method and related apparatus
US5714341A (en) * 1994-03-30 1998-02-03 Epitope, Inc. Saliva assay method and device
US5695930A (en) * 1994-11-10 1997-12-09 Weinstein; David E. HIV test kit method for detecting anti-HIV-I antibodies in saliva
IT1274481B (en) 1995-05-12 1997-07-17 Indena Spa PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ALCOHOL-DEPENDENCE
US5695929A (en) * 1995-06-07 1997-12-09 Goldstein; Andrew S. Substitute saliva standard
US5786228A (en) * 1995-06-07 1998-07-28 Biex, Inc. Fluid collection kit and method
US5786227A (en) * 1995-06-07 1998-07-28 Biex, Inc. Fluid collection kit and method
WO1997014800A1 (en) * 1995-10-16 1997-04-24 Smithkline Beecham Plc Novel saliva binding protein
US5830154A (en) * 1996-01-11 1998-11-03 Epitope, Inc. Device for collecting substances for testing
TW452494B (en) 1996-03-12 2001-09-01 Jang De Shan Herbal composition for stimulating blood circulation
US5935864A (en) 1996-10-07 1999-08-10 Saliva Diagnostic Systems Inc. Method and kit for collecting samples of liquid specimens for analytical testing
US5994400A (en) 1996-12-05 1999-11-30 Georgetown University School Of Medicine Extracts of salvia species having antiviral activity
US5908771A (en) 1997-01-31 1999-06-01 R. J. Reynolds Tobacco Company Method for regeneration of salvia species
EP0875250A1 (en) 1997-04-29 1998-11-04 Heilmittelbetrieb Isernhagen GmbH Use of an extract of Salvia officinalis to combat the Dupuytren's contracture
US5989840A (en) 1997-05-29 1999-11-23 Americare International Diagnostics, Inc. Estimation of active infection by heliobacter pylori
US5891697A (en) 1997-09-25 1999-04-06 Washington State University Research Foundation Monoterpene synthases from common sage (Salvia officinalis)

Also Published As

Publication number Publication date
EP1032709A1 (en) 2000-09-06
WO1999027139A1 (en) 1999-06-03
US5968746A (en) 1999-10-19
AU1602199A (en) 1999-06-15
NZ505342A (en) 2002-03-28
EP1032709B1 (en) 2008-06-11
CA2310616C (en) 2009-02-03
EP1032709A4 (en) 2007-01-10
DE69839613D1 (en) 2008-07-24
JP2001524321A (en) 2001-12-04
ATE397891T1 (en) 2008-07-15
AU754598B2 (en) 2002-11-21
US6291178B1 (en) 2001-09-18

Similar Documents

Publication Publication Date Title
CA2310616A1 (en) Method and apparatus for preserving human saliva for testing
BG104275A (en) Method and device for express analysis of tested parameters in biological samples
CA2326530A1 (en) Test methods, devices and test kits for fertility
CA2185555A1 (en) Integrated system for biological fluid constituent analysis
CA2324413A1 (en) Device and methods for single step collection and assaying of biological fluids
DE69416828D1 (en) DEVICE FOR CHROMATOGRAPHIC DETERMINATION CONTAINING COMPARABLE PARTS
MXPA06003765A (en) Diagnostic test device and method of using same.
CA2163858A1 (en) Improved method and analytical system for performing fibrinogen assays accurately, rapidly and simply
DE69837087D1 (en) ANALYSIS DEVICE WITH REMOVABLE ELEMENT
CA2435550A1 (en) System for monitoring the concentration of analytes in body fluids
NO982156L (en) Diagnostic test device
WO2003008933A3 (en) Test strip for a lateral flow assay
CA2173966A1 (en) Analytical Devices and Methods of Use Thereof
EP1605263A3 (en) Methods, composition and kit for measuring expression of a cell-surface
CA2162531A1 (en) Method for specifically detecting a coagulation factor v which has an increased stability toward activated protein c in the activated state
CA2283154A1 (en) Method and apparatus for measurement of blood substitutes
CA2341263A1 (en) Enzyme inhibition immunoassay
CA2263535A1 (en) Method for continuous or discontinuous automatic analysing of samples placed in containers
CA2285219A1 (en) Detection of low level analytes in samples
AU1245188A (en) Analyte detection in particulate-containing samples
CA2253527A1 (en) Method of assay
EP1640701A3 (en) Method and apparatus for analyte concentration free of intermediate transfer
CA2242693A1 (en) Additive formulation and method of use thereof
WO2003089896A3 (en) Rapid assay, method and system for detecting biowarfare agents
CA2520438A1 (en) Latex reagent for adiponectin analysis and method of adiponectin analysis

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20141124