CA2302601A1 - Transdermal therapeutic system comprising a reservoir-type pressure-sensitive adhesive layer and a back layer with uni-directional resilience - Google Patents
Transdermal therapeutic system comprising a reservoir-type pressure-sensitive adhesive layer and a back layer with uni-directional resilience Download PDFInfo
- Publication number
- CA2302601A1 CA2302601A1 CA002302601A CA2302601A CA2302601A1 CA 2302601 A1 CA2302601 A1 CA 2302601A1 CA 002302601 A CA002302601 A CA 002302601A CA 2302601 A CA2302601 A CA 2302601A CA 2302601 A1 CA2302601 A1 CA 2302601A1
- Authority
- CA
- Canada
- Prior art keywords
- sensitive adhesive
- therapeutic system
- transdermal therapeutic
- uni
- reservoir
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000010410 layer Substances 0.000 title abstract 4
- 239000004820 Pressure-sensitive adhesive Substances 0.000 title abstract 3
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000013013 elastic material Substances 0.000 abstract 1
- 239000011505 plaster Substances 0.000 abstract 1
- 239000011241 protective layer Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A transdermal therapeutic system (TTS), in particular a patch, is described, comprising - a redetachable protective layer, - a pressure-sensitive adhesive reservoir layer and - a backing layer with or without a coating of pressure-sensitive adhesive and featuring a unidirectionally, preferably longitudinally, elastic material having an elasticity of at least 20%. The TTS is particularly suitable for use as a multi-day plaster, for the treatment, for instance, of pain or of drug dependency.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19738855.8 | 1997-09-05 | ||
DE19738855A DE19738855C2 (en) | 1997-09-05 | 1997-09-05 | Transdermal therapeutic system with adhesive reservoir layer and unidirectional elastic back layer |
PCT/EP1998/005321 WO1999012529A2 (en) | 1997-09-05 | 1998-08-21 | Transdermal therapeutic system comprising a reservoir-type pressure-sensitive adhesive layer and a back layer with uni-directional resilience |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2302601A1 true CA2302601A1 (en) | 1999-03-18 |
CA2302601C CA2302601C (en) | 2006-06-13 |
Family
ID=7841309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002302601A Expired - Lifetime CA2302601C (en) | 1997-09-05 | 1998-08-21 | Transdermal therapeutic system comprising a reservoir-type pressure-sensitive adhesive layer and a back layer with uni-directional resilience |
Country Status (14)
Country | Link |
---|---|
US (2) | US6814976B1 (en) |
EP (1) | EP1009393B1 (en) |
JP (1) | JP3847088B2 (en) |
KR (1) | KR100515007B1 (en) |
AT (1) | ATE215364T1 (en) |
AU (1) | AU738033B2 (en) |
CA (1) | CA2302601C (en) |
DE (2) | DE19738855C2 (en) |
DK (1) | DK1009393T3 (en) |
ES (1) | ES2175792T3 (en) |
NO (1) | NO327605B1 (en) |
PT (1) | PT1009393E (en) |
SI (1) | SI1009393T1 (en) |
WO (1) | WO1999012529A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6756052B1 (en) | 1999-05-21 | 2004-06-29 | Lts Lohmann Therapie-Systeme Ag | Device and method for increasing the transdermal permeation of medicaments |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
DE10042412B4 (en) * | 2000-08-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | Transceiver for bus subscriber of bus system of building system engineering, has two wires, where microcontroller is connected with receiver unit over connection on one hand, which is connected to two wires of bus system |
GB0117583D0 (en) * | 2001-07-19 | 2001-09-12 | Astrazeneca Ab | Novel compounds |
DE10159745A1 (en) * | 2001-12-05 | 2003-07-03 | Lohmann Therapie Syst Lts | Transdermal therapeutic system with improved long-term comfort |
EP1795189A3 (en) * | 2002-03-20 | 2007-08-15 | Euro-Celtique S.A. | Method of administering buprenorphine to treat depression |
DK1485051T3 (en) * | 2002-03-20 | 2008-09-08 | Euro Celtique Sa | Method of administration of buprenorphine for the treatment of depression |
DE10305137A1 (en) * | 2003-02-07 | 2004-08-26 | Novosis Ag | Transdermal therapeutic delivery systems with a butenolide |
ATE487492T1 (en) * | 2003-02-27 | 2010-11-15 | Eisai R&D Man Co Ltd | PHARMACEUTICAL COMPOSITION FOR TREATING DRUG DEPENDENCE |
US7052052B2 (en) * | 2003-03-13 | 2006-05-30 | Donaldson Company, Inc. | Sealing gasket for a clamp |
RU2356580C2 (en) * | 2003-10-28 | 2009-05-27 | Новен Фармасьютикалз, Инк | Compositions and methods providing controlled drug loss and delivery within transdermal drug delivery systems |
DE102004012442C5 (en) | 2004-03-13 | 2012-01-26 | Paul Hartmann Ag | Elastic bandage segment |
US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
AU2005284908B2 (en) | 2004-09-13 | 2011-12-08 | Morningside Venture Investments Limited | Biosynchronous transdermal drug delivery |
EP1924296B1 (en) * | 2005-09-13 | 2009-02-18 | Sabine Hohmann | Dressing material comprising active substances |
US7955677B2 (en) * | 2005-12-07 | 2011-06-07 | Mylan Technologies, Inc. | Two-sided non-stick release film |
US7816394B2 (en) * | 2005-12-20 | 2010-10-19 | Teikoku Pharma Usa Inc. | Methods of transdermally administering an indole serotonin receptor agonist and transdermal compositions for use in the same |
EP2170063A1 (en) * | 2007-07-23 | 2010-04-07 | Teikoku Pharma USA, Inc. | Organoleptically acceptable indole serotonin receptor agonist oral dosage formulations and methods of using the same |
WO2009024284A2 (en) * | 2007-08-21 | 2009-02-26 | Lts Lohmann Therapie-Systeme Ag | Method for the multi-track tailoring of transdermal therapeutic patches |
DE102008059054A1 (en) | 2008-11-26 | 2010-05-27 | Otto Bock Pur Life Science Gmbh | Polyurethane patch for the transdermal application of active substances and process for its preparation |
US8299079B2 (en) | 2009-05-22 | 2012-10-30 | Kaufman Herbert E | Preparations and methods for ameliorating or reducing presbyopia |
DE102009056746A1 (en) * | 2009-12-04 | 2011-06-09 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system for the administration of peptides |
EP2366388A1 (en) * | 2010-03-17 | 2011-09-21 | Ratiopharm GmbH | Non-occlusive transdermal therapeutic system for administering buprenorphine |
WO2013006643A1 (en) | 2011-07-06 | 2013-01-10 | The Parkinson's Institute | Compositions and methods for treatment of symptoms in parkinson's disease patients |
DE102014007650A1 (en) | 2013-05-24 | 2014-11-27 | Amw Gmbh | Plaster with bielastic backing layer |
MX362614B (en) | 2013-06-04 | 2019-01-28 | Lts Lohmann Therapie Systeme Ag | Transdermal delivery system. |
EP2921184A1 (en) * | 2014-03-19 | 2015-09-23 | LTS LOHMANN Therapie-Systeme AG | Finishing plaster having improved tolerability and a long adhesive period and method for producing the same |
DE102014013448A1 (en) | 2014-09-16 | 2016-03-17 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermal therapeutic system comprising buprenorphine |
US9656441B2 (en) | 2015-01-08 | 2017-05-23 | Alfred E. Tiefenbacher ( Gmbh & Co. Kg) | Transdermal patch |
WO2016123406A1 (en) | 2015-01-28 | 2016-08-04 | Chrono Therapeutics Inc. | Drug delivery methods and systems |
CA2977814A1 (en) | 2015-03-12 | 2016-09-15 | Chrono Therapeutics Inc. | Craving input and support system |
EP3067050A1 (en) | 2015-03-13 | 2016-09-14 | Acino AG | Transdermal therapeutic system with an overtape comprising two adhesive layers |
PL3297591T3 (en) | 2015-05-21 | 2023-05-15 | Adhexpharma Sas | Plaster with bi-elastic backing layer |
DE102015006599A1 (en) | 2015-05-21 | 2016-11-24 | Amw Gmbh | Plaster with bielastic backing layer |
DE102016105889A1 (en) * | 2016-03-31 | 2017-10-05 | Amw Gmbh | Transdermal application system with information layer |
EP3565617A1 (en) | 2017-01-06 | 2019-11-13 | Chrono Therapeutics Inc. | Transdermal drug delivery devices and methods |
DE102017112543A1 (en) * | 2017-06-07 | 2018-12-13 | Amw Gmbh | Overtape for a transdermal delivery system |
GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
CN107753181A (en) * | 2017-10-19 | 2018-03-06 | 中国计量大学 | The topical application of drug device of disease of skin |
CA3101966A1 (en) | 2018-05-29 | 2019-12-05 | Morningside Venture Investments Limited | Drug delivery methods and systems |
EP3955918A1 (en) | 2019-04-17 | 2022-02-23 | COMPASS Pathfinder Limited | Methods of treating neurocognitive disorders, chronic pain and reducing inflammation |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE166944C (en) * | ||||
DE1667944A1 (en) * | 1968-02-24 | 1971-07-22 | Friedrich Homann | Adhesive plasters, adhesive plasters, bandages or the like. with an elastically stretchable fabric underlay in the transverse or in the longitudinal direction |
FR2366014A1 (en) * | 1976-07-26 | 1978-04-28 | Lhd Lab Hygiene Dietetique | Adhesive surgical prod. with nonwoven support - which is elastic in all directions |
CA1070217A (en) * | 1976-12-10 | 1980-01-22 | Karl Otto Braun Kg | Wide bandage fabric |
US4291015A (en) * | 1979-08-14 | 1981-09-22 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix containing a vasodilator |
JPS5843368B2 (en) * | 1980-10-30 | 1983-09-27 | 日東電工株式会社 | Anti-inflammatory analgesic patch |
US4661509A (en) * | 1982-09-28 | 1987-04-28 | Gordon Arnold Z | Methods for treating leukopenia |
US4780168A (en) | 1984-10-22 | 1988-10-25 | Genetic Laboratories, Inc. | Wound closure strips |
US4994278A (en) * | 1988-03-04 | 1991-02-19 | Noven Pharmaceuticals, Inc. | Breathable backing |
DE3939376C1 (en) | 1989-11-29 | 1991-05-08 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg, 5450 Neuwied, De | |
US5240711A (en) * | 1989-11-29 | 1993-08-31 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal therapeutic system comprising as active component buprenorphine |
US5087248A (en) * | 1990-02-20 | 1992-02-11 | Genetic Laboratories Wound Care, Inc. | Device for anchoring an intravenous needle |
KR950005865B1 (en) * | 1990-04-23 | 1995-06-02 | 데이진 가부시끼가이샤 | Plaster |
DE4110027C2 (en) | 1991-03-27 | 1996-08-29 | Lohmann Therapie Syst Lts | Process for packaging transdermal therapeutic patches |
US5246705A (en) * | 1992-04-08 | 1993-09-21 | Cygnus Therapeutic System | Occlusive, elastomeric backing materials in transdermal drug delivery systems, and associated methods of manufacture and use |
DE4333595A1 (en) * | 1993-10-01 | 1995-04-06 | Labtec Gmbh | Transdermal therapeutic system for applying drugs to the skin |
DE4423850A1 (en) * | 1994-07-07 | 1996-01-11 | Labtec Gmbh | Transdermal delivery device for naloxone hydrochloride |
US5846558A (en) * | 1996-03-19 | 1998-12-08 | Minnesota Mining And Manufacturing Company | Ionically conductive adhesives prepared from zwitterionic materials and medical devices using such adhesives |
-
1997
- 1997-09-05 DE DE19738855A patent/DE19738855C2/en not_active Expired - Fee Related
-
1998
- 1998-08-21 CA CA002302601A patent/CA2302601C/en not_active Expired - Lifetime
- 1998-08-21 SI SI9830189T patent/SI1009393T1/en unknown
- 1998-08-21 KR KR10-2000-7002344A patent/KR100515007B1/en not_active IP Right Cessation
- 1998-08-21 AT AT98948853T patent/ATE215364T1/en active
- 1998-08-21 DE DE59803647T patent/DE59803647D1/en not_active Expired - Lifetime
- 1998-08-21 AU AU95329/98A patent/AU738033B2/en not_active Ceased
- 1998-08-21 JP JP2000510427A patent/JP3847088B2/en not_active Expired - Lifetime
- 1998-08-21 US US09/486,266 patent/US6814976B1/en not_active Expired - Lifetime
- 1998-08-21 EP EP98948853A patent/EP1009393B1/en not_active Expired - Lifetime
- 1998-08-21 PT PT98948853T patent/PT1009393E/en unknown
- 1998-08-21 DK DK98948853T patent/DK1009393T3/en active
- 1998-08-21 WO PCT/EP1998/005321 patent/WO1999012529A2/en active IP Right Grant
- 1998-08-21 ES ES98948853T patent/ES2175792T3/en not_active Expired - Lifetime
-
2000
- 2000-02-28 NO NO20001003A patent/NO327605B1/en not_active IP Right Cessation
-
2004
- 2004-07-15 US US10/891,942 patent/US7384651B2/en not_active Expired - Fee Related
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6756052B1 (en) | 1999-05-21 | 2004-06-29 | Lts Lohmann Therapie-Systeme Ag | Device and method for increasing the transdermal permeation of medicaments |
Also Published As
Publication number | Publication date |
---|---|
CA2302601C (en) | 2006-06-13 |
AU738033B2 (en) | 2001-09-06 |
WO1999012529A3 (en) | 1999-05-27 |
JP3847088B2 (en) | 2006-11-15 |
NO20001003D0 (en) | 2000-02-28 |
NO20001003L (en) | 2000-02-28 |
ATE215364T1 (en) | 2002-04-15 |
US6814976B1 (en) | 2004-11-09 |
ES2175792T3 (en) | 2002-11-16 |
US20040253301A1 (en) | 2004-12-16 |
DE19738855A1 (en) | 1999-03-11 |
KR20010023691A (en) | 2001-03-26 |
EP1009393A2 (en) | 2000-06-21 |
AU9532998A (en) | 1999-03-29 |
DE59803647D1 (en) | 2002-05-08 |
SI1009393T1 (en) | 2002-10-31 |
DE19738855C2 (en) | 2001-01-04 |
NO327605B1 (en) | 2009-08-31 |
WO1999012529A2 (en) | 1999-03-18 |
KR100515007B1 (en) | 2005-09-14 |
JP2001515856A (en) | 2001-09-25 |
DK1009393T3 (en) | 2002-07-22 |
EP1009393B1 (en) | 2002-04-03 |
PT1009393E (en) | 2002-09-30 |
US7384651B2 (en) | 2008-06-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20180821 |