CA2295132A1 - Apparatus and methods for assessment of neuromuscular function - Google Patents

Apparatus and methods for assessment of neuromuscular function Download PDF

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Publication number
CA2295132A1
CA2295132A1 CA002295132A CA2295132A CA2295132A1 CA 2295132 A1 CA2295132 A1 CA 2295132A1 CA 002295132 A CA002295132 A CA 002295132A CA 2295132 A CA2295132 A CA 2295132A CA 2295132 A1 CA2295132 A1 CA 2295132A1
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CA
Canada
Prior art keywords
assessment
nerve
neuromuscular function
wrist
stimulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002295132A
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French (fr)
Other versions
CA2295132C (en
Inventor
Shai N. Gozani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neurometrix Inc
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Individual
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Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2295132A1 publication Critical patent/CA2295132A1/en
Application granted granted Critical
Publication of CA2295132C publication Critical patent/CA2295132C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A61B5/1104—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb induced by stimuli or drugs
    • A61B5/1106—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb induced by stimuli or drugs to assess neuromuscular blockade, e.g. to estimate depth of anaesthesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/389—Electromyography [EMG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/389—Electromyography [EMG]
    • A61B5/395—Details of stimulation, e.g. nerve stimulation to elicit EMG response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4029—Detecting, measuring or recording for evaluating the nervous system for evaluating the peripheral nervous systems
    • A61B5/4041—Evaluating nerves condition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2505/00—Evaluating, monitoring or diagnosing in the context of a particular type of medical care
    • A61B2505/05—Surgical care
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6824—Arm or wrist
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6825—Hand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7217—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise originating from a therapeutic or surgical apparatus, e.g. from a pacemaker
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7239—Details of waveform analysis using differentiation including higher order derivatives

Abstract

Apparatus and methods are provided for the assessment of neuromuscular function. Using an apparatus of the invention, stimuli are applied to a nerve that traverses the wrist of an individual. The stimuli are applied at a point that is proximal to the wrist. Stimulation of the nerve causes a muscle innervated by that nerve to respond. The muscle response generates a myoeletric potential, which is detected by an apparatus of the invention at a point that is proximal to the wrist. The delay between stimulation of a nerve and detection of a muscular response to that stimulation is processed to indicate an assessment of neuromuscular function. For example, a sufficient delay between application of stimulus and muscle response may indicate the presence of Carpal Tunnel Syndrome.
CA002295132A 1997-07-01 1998-06-22 Apparatus and methods for assessment of neuromuscular function Expired - Fee Related CA2295132C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/886,861 US5851191A (en) 1997-07-01 1997-07-01 Apparatus and methods for assessment of neuromuscular function
US08/886,861 1997-07-01
PCT/US1998/012922 WO1999001064A1 (en) 1997-07-01 1998-06-22 Apparatus and methods for assessment of neuromuscular function

Publications (2)

Publication Number Publication Date
CA2295132A1 true CA2295132A1 (en) 1999-01-14
CA2295132C CA2295132C (en) 2004-09-14

Family

ID=25389937

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002295132A Expired - Fee Related CA2295132C (en) 1997-07-01 1998-06-22 Apparatus and methods for assessment of neuromuscular function

Country Status (8)

Country Link
US (3) US5851191A (en)
EP (1) EP0993270B1 (en)
JP (2) JP3657277B2 (en)
AT (1) ATE375116T1 (en)
AU (1) AU750315B2 (en)
CA (1) CA2295132C (en)
DE (1) DE69838549D1 (en)
WO (1) WO1999001064A1 (en)

Families Citing this family (159)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6132386A (en) * 1997-07-01 2000-10-17 Neurometrix, Inc. Methods for the assessment of neuromuscular function by F-wave latency
US7628761B2 (en) * 1997-07-01 2009-12-08 Neurometrix, Inc. Apparatus and method for performing nerve conduction studies with localization of evoked responses
US6564078B1 (en) 1998-12-23 2003-05-13 Nuvasive, Inc. Nerve surveillance cannula systems
WO2000038574A1 (en) 1998-12-23 2000-07-06 Nuvasive, Inc. Nerve surveillance cannulae systems
CA2363254C (en) 1999-03-07 2009-05-05 Discure Ltd. Method and apparatus for computerized surgery
WO2000076400A1 (en) * 1999-06-14 2000-12-21 Agee, John M., Trustee Of The John M. Agee Trust Dated August 15, 1996 Method and apparatus for monitoring tendon motion
DE69938660D1 (en) * 1999-10-29 2008-06-19 Compex Medical Sa Neuromuscular stimulation device with recording of the muscle reaction to the electrical stimulation pulse
EP1237472A4 (en) 1999-11-24 2008-04-30 Nuvasive Inc Electromyography system
US6466817B1 (en) * 1999-11-24 2002-10-15 Nuvasive, Inc. Nerve proximity and status detection system and method
US6760616B2 (en) 2000-05-18 2004-07-06 Nu Vasive, Inc. Tissue discrimination and applications in medical procedures
US20020055688A1 (en) * 2000-05-18 2002-05-09 Jefferson Jacob Katims Nervous tissue stimulation device and method
WO2001093748A2 (en) 2000-06-08 2001-12-13 Nuvasive, Inc. Relative nerve movement and status detection system and method
US6564079B1 (en) 2000-07-27 2003-05-13 Ckm Diagnostics, Inc. Electrode array and skin attachment system for noninvasive nerve location and imaging device
US20030105503A1 (en) * 2001-06-08 2003-06-05 Nuvasive, Inc. Relative nerve movement and status detection system and method
WO2003005887A2 (en) 2001-07-11 2003-01-23 Nuvasive, Inc. System and methods for determining nerve proximity, direction, and pathology during surgery
EP2481338A3 (en) 2001-09-25 2012-09-05 Nuvasive, Inc. System for performing surgical procedures and assessments
US7664544B2 (en) 2002-10-30 2010-02-16 Nuvasive, Inc. System and methods for performing percutaneous pedicle integrity assessments
US6829510B2 (en) * 2001-12-18 2004-12-07 Ness Neuromuscular Electrical Stimulation Systems Ltd. Surface neuroprosthetic device having an internal cushion interface system
US8147421B2 (en) 2003-01-15 2012-04-03 Nuvasive, Inc. System and methods for determining nerve direction to a surgical instrument
US7582058B1 (en) 2002-06-26 2009-09-01 Nuvasive, Inc. Surgical access system and related methods
US8137284B2 (en) 2002-10-08 2012-03-20 Nuvasive, Inc. Surgical access system and related methods
US7691057B2 (en) 2003-01-16 2010-04-06 Nuvasive, Inc. Surgical access system and related methods
US9462960B2 (en) * 2003-02-21 2016-10-11 3Dt Holdings, Llc Impedance devices and methods of using the same to obtain luminal organ measurements
US7819801B2 (en) 2003-02-27 2010-10-26 Nuvasive, Inc. Surgical access system and related methods
US20040225228A1 (en) 2003-05-08 2004-11-11 Ferree Bret A. Neurophysiological apparatus and procedures
JP4436836B2 (en) 2003-08-05 2010-03-24 ヌヴァシヴ インコーポレイテッド System and method for performing dynamic pedicle integrity assessment
US7179231B2 (en) * 2003-08-25 2007-02-20 Wisys Technology Foundation, Inc., Apparatus and method for analyzing nerve conduction
WO2005030318A1 (en) 2003-09-25 2005-04-07 Nuvasive, Inc. Surgical access system and related methods
US7905840B2 (en) 2003-10-17 2011-03-15 Nuvasive, Inc. Surgical access system and related methods
SE0302746D0 (en) * 2003-10-17 2003-10-17 Uppsala Laekarkonsult Ab multielectrode
US8313430B1 (en) 2006-01-11 2012-11-20 Nuvasive, Inc. Surgical access system and related methods
US8326410B2 (en) * 2004-02-17 2012-12-04 Neurometrix, Inc. Method for automated analysis of submaximal F-waves
WO2007022524A2 (en) 2005-08-19 2007-02-22 Neuronetrix, Inc. Controller for neuromuscular testing
US9622732B2 (en) 2004-10-08 2017-04-18 Nuvasive, Inc. Surgical access system and related methods
US20110190772A1 (en) 2004-10-15 2011-08-04 Vahid Saadat Powered tissue modification devices and methods
US7938830B2 (en) 2004-10-15 2011-05-10 Baxano, Inc. Powered tissue modification devices and methods
US9101386B2 (en) 2004-10-15 2015-08-11 Amendia, Inc. Devices and methods for treating tissue
US8062300B2 (en) 2006-05-04 2011-11-22 Baxano, Inc. Tissue removal with at least partially flexible devices
US7555343B2 (en) 2004-10-15 2009-06-30 Baxano, Inc. Devices and methods for selective surgical removal of tissue
US7887538B2 (en) 2005-10-15 2011-02-15 Baxano, Inc. Methods and apparatus for tissue modification
US9247952B2 (en) 2004-10-15 2016-02-02 Amendia, Inc. Devices and methods for tissue access
JP5243034B2 (en) 2004-10-15 2013-07-24 バクサノ，インク． Tissue removal device
US20100331883A1 (en) 2004-10-15 2010-12-30 Schmitz Gregory P Access and tissue modification systems and methods
US7738969B2 (en) 2004-10-15 2010-06-15 Baxano, Inc. Devices and methods for selective surgical removal of tissue
US7578819B2 (en) 2005-05-16 2009-08-25 Baxano, Inc. Spinal access and neural localization
US8048080B2 (en) 2004-10-15 2011-11-01 Baxano, Inc. Flexible tissue rasp
US8430881B2 (en) 2004-10-15 2013-04-30 Baxano, Inc. Mechanical tissue modification devices and methods
US7857813B2 (en) 2006-08-29 2010-12-28 Baxano, Inc. Tissue access guidewire system and method
US8613745B2 (en) 2004-10-15 2013-12-24 Baxano Surgical, Inc. Methods, systems and devices for carpal tunnel release
US8257356B2 (en) 2004-10-15 2012-09-04 Baxano, Inc. Guidewire exchange systems to treat spinal stenosis
US8221397B2 (en) 2004-10-15 2012-07-17 Baxano, Inc. Devices and methods for tissue modification
EP1656883A1 (en) * 2004-11-10 2006-05-17 Universite Libre De Bruxelles Portable device for measuring EMG signal
US7785253B1 (en) 2005-01-31 2010-08-31 Nuvasive, Inc. Surgical access system and related methods
US7643884B2 (en) 2005-01-31 2010-01-05 Warsaw Orthopedic, Inc. Electrically insulated surgical needle assembly
US20060173374A1 (en) * 2005-01-31 2006-08-03 Neubardt Seth L Electrically insulated surgical probing tool
WO2006084193A2 (en) 2005-02-02 2006-08-10 Nuvasive, Inc. System and methods for performing neurophysiologic assessments during spine surgery
WO2006084194A2 (en) 2005-02-02 2006-08-10 Nuvasive, Inc. System and methods for monitoring during anterior surgery
US7424322B2 (en) * 2005-02-03 2008-09-09 Cardinal Health 209, Inc. Method and apparatus for stimulus artifact suppression
US8092455B2 (en) 2005-02-07 2012-01-10 Warsaw Orthopedic, Inc. Device and method for operating a tool relative to bone tissue and detecting neural elements
US20060178594A1 (en) * 2005-02-07 2006-08-10 Neubardt Seth L Apparatus and method for locating defects in bone tissue
US20060200023A1 (en) * 2005-03-04 2006-09-07 Sdgi Holdings, Inc. Instruments and methods for nerve monitoring in spinal surgical procedures
US20070129771A1 (en) * 2005-04-20 2007-06-07 Kurtz Ronald L Device, method and stimulus unit for testing neuromuscular function
US20070185409A1 (en) * 2005-04-20 2007-08-09 Jianping Wu Method and system for determining an operable stimulus intensity for nerve conduction testing
US20060253167A1 (en) * 2005-04-20 2006-11-09 Kurtz Ronald L Device, method and stimulus unit for testing neuromuscular function
US7640057B2 (en) * 2005-04-25 2009-12-29 Cardiac Pacemakers, Inc. Methods of providing neural markers for sensed autonomic nervous system activity
WO2006119532A1 (en) * 2005-05-13 2006-11-16 Mcleay, Charmaine, A., M. Detection of muscular disorders
US8740783B2 (en) 2005-07-20 2014-06-03 Nuvasive, Inc. System and methods for performing neurophysiologic assessments with pressure monitoring
US8328851B2 (en) 2005-07-28 2012-12-11 Nuvasive, Inc. Total disc replacement system and related methods
US8206312B2 (en) 2005-09-22 2012-06-26 Nuvasive, Inc. Multi-channel stimulation threshold detection algorithm for use in neurophysiology monitoring
US8568317B1 (en) 2005-09-27 2013-10-29 Nuvasive, Inc. System and methods for nerve monitoring
US8366712B2 (en) 2005-10-15 2013-02-05 Baxano, Inc. Multiple pathways for spinal nerve root decompression from a single access point
US8062298B2 (en) 2005-10-15 2011-11-22 Baxano, Inc. Flexible tissue removal devices and methods
US8092456B2 (en) 2005-10-15 2012-01-10 Baxano, Inc. Multiple pathways for spinal nerve root decompression from a single access point
US9014798B2 (en) * 2005-10-20 2015-04-21 Neurometrix, Inc. Automated stimulus artifact removal for nerve conduction studies
US7632239B2 (en) * 2005-11-16 2009-12-15 Bioness Neuromodulation Ltd. Sensor device for gait enhancement
JP4738159B2 (en) * 2005-12-12 2011-08-03 株式会社Ｉｈｉ Electromyography device for myoelectric potential measurement
US20070149892A1 (en) * 2005-12-22 2007-06-28 Neurotron Medical Inc. Apparatus for neuromuscular function signal acquisition
US20100168501A1 (en) * 2006-10-02 2010-07-01 Daniel Rogers Burnett Method and apparatus for magnetic induction therapy
US9610459B2 (en) * 2009-07-24 2017-04-04 Emkinetics, Inc. Cooling systems and methods for conductive coils
US9339641B2 (en) * 2006-01-17 2016-05-17 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
CA2649663C (en) 2006-05-01 2017-03-14 Bioness Neuromodulation Ltd. Improved functional electrical stimulation systems
CA2556165A1 (en) * 2006-08-08 2008-02-08 Richard Kerber Method and apparatus for precluding plant trunks from freezing
US7917201B2 (en) * 2006-08-23 2011-03-29 Neurometrix, Inc. Method and apparatus for determining optimal neuromuscular detection sites, novel diagnostic biosensor array formed in accordance with the same, and novel method for testing a patient using the novel diagnostic biosensor array
CA2665121C (en) * 2006-09-16 2013-11-26 Terence Gilhuly Modeling and control for highly variable and nonlinear processes
US11224742B2 (en) 2006-10-02 2022-01-18 Emkinetics, Inc. Methods and devices for performing electrical stimulation to treat various conditions
US10786669B2 (en) 2006-10-02 2020-09-29 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US9005102B2 (en) 2006-10-02 2015-04-14 Emkinetics, Inc. Method and apparatus for electrical stimulation therapy
WO2008076372A2 (en) * 2006-12-15 2008-06-26 Neurometrix, Inc. Neurological diagnostic and therapeutic system utilizing function-specific modules
JP5005331B2 (en) * 2006-12-19 2012-08-22 富士重工業株式会社 Muscle force sensor
US20080183074A1 (en) * 2007-01-25 2008-07-31 Warsaw Orthopedic, Inc. Method and apparatus for coordinated display of anatomical and neuromonitoring information
US8374673B2 (en) 2007-01-25 2013-02-12 Warsaw Orthopedic, Inc. Integrated surgical navigational and neuromonitoring system having automated surgical assistance and control
US7987001B2 (en) 2007-01-25 2011-07-26 Warsaw Orthopedic, Inc. Surgical navigational and neuromonitoring instrument
US8255045B2 (en) * 2007-04-03 2012-08-28 Nuvasive, Inc. Neurophysiologic monitoring system
US9042978B2 (en) * 2007-05-11 2015-05-26 Neurometrix, Inc. Method and apparatus for quantitative nerve localization
EP2194861A1 (en) 2007-09-06 2010-06-16 Baxano, Inc. Method, system and apparatus for neural localization
US8192436B2 (en) 2007-12-07 2012-06-05 Baxano, Inc. Tissue modification devices
US8398641B2 (en) 2008-07-01 2013-03-19 Baxano, Inc. Tissue modification devices and methods
US9314253B2 (en) 2008-07-01 2016-04-19 Amendia, Inc. Tissue modification devices and methods
US8409206B2 (en) 2008-07-01 2013-04-02 Baxano, Inc. Tissue modification devices and methods
CA2730732A1 (en) 2008-07-14 2010-01-21 Baxano, Inc. Tissue modification devices
US8271659B2 (en) * 2008-09-04 2012-09-18 Oracle International Corporation Methods and systems for automatic removal and replacement of connections in a pool rendered stale by a firewall
WO2010057495A2 (en) * 2008-11-18 2010-05-27 Sense A/S Methods, apparatus and sensor for measurement of cardiovascular quantities
US9084551B2 (en) 2008-12-08 2015-07-21 Medtronic Xomed, Inc. Method and system for monitoring a nerve
WO2010075555A2 (en) 2008-12-26 2010-07-01 Scott Spann Minimally-invasive retroperitoneal lateral approach for spinal surgery
US20100210965A1 (en) * 2009-02-13 2010-08-19 Gozani Shai N Apparatus and method for the detection of neuromuscular signals
CA2749673A1 (en) 2009-03-13 2010-09-16 Baxano, Inc. Flexible neural localization devices and methods
US9351845B1 (en) 2009-04-16 2016-05-31 Nuvasive, Inc. Method and apparatus for performing spine surgery
US8287597B1 (en) 2009-04-16 2012-10-16 Nuvasive, Inc. Method and apparatus for performing spine surgery
EP2434949B1 (en) * 2009-05-29 2015-09-23 Koninklijke Philips N.V. Enclosure for a CAPACITIVE SENSING APPARATUS and method
US8394102B2 (en) 2009-06-25 2013-03-12 Baxano, Inc. Surgical tools for treatment of spinal stenosis
JP2013508119A (en) 2009-10-26 2013-03-07 エムキネティクス， インコーポレイテッド Method and apparatus for electromagnetic stimulation of nerves, muscles and body tissues
US20110230785A1 (en) * 2010-03-16 2011-09-22 ProNerve, LLC Somatosensory Evoked Potential (SSEP) Automated Alert System
US9775531B2 (en) * 2010-06-09 2017-10-03 Techmedic Development International B.V. Sensor device, processing device, and measurement system for acquiring a biopotential
ES2720127T3 (en) 2010-09-16 2019-07-18 Neurometrix Inc Automated speed and amplitude conduction measuring instrument of the sural nerve
US10004445B2 (en) 2010-09-16 2018-06-26 Neurometrix, Inc. Apparatus and method for stimulator on-skin short detection
US9392953B1 (en) 2010-09-17 2016-07-19 Nuvasive, Inc. Neurophysiologic monitoring
US9095417B2 (en) 2011-02-07 2015-08-04 Bioness Neuromodulation Ltd. Adjustable orthosis for electrical stimulation of a limb
US8790406B1 (en) 2011-04-01 2014-07-29 William D. Smith Systems and methods for performing spine surgery
WO2012155185A1 (en) 2011-05-13 2012-11-22 National Ict Australia Ltd Method and apparatus for measurement of neural response
US9974455B2 (en) 2011-05-13 2018-05-22 Saluda Medical Pty Ltd. Method and apparatus for estimating neural recruitment
CN103648583B (en) 2011-05-13 2016-01-20 萨鲁达医疗有限公司 For measuring method and the instrument of nerves reaction-A
US8868217B2 (en) 2011-06-27 2014-10-21 Bioness Neuromodulation Ltd. Electrode for muscle stimulation
US10166018B2 (en) 2011-08-19 2019-01-01 Nuvasive, Inc. Surgical retractor system and methods of use
US9198765B1 (en) 2011-10-31 2015-12-01 Nuvasive, Inc. Expandable spinal fusion implants and related methods
WO2013112853A1 (en) * 2012-01-27 2013-08-01 T4 Analytics Llc Anesthesia monitoring systems and methods of monitoring anesthesia
JP2015506246A (en) * 2012-01-27 2015-03-02 ティー４・アナリティクス・リミテッド・ライアビリティ・カンパニー Method and system for assessing muscle electrical activity in response to motor nerve stimulation
US11877860B2 (en) 2012-11-06 2024-01-23 Nuvasive, Inc. Systems and methods for performing neurophysiologic monitoring during spine surgery
US11259737B2 (en) 2012-11-06 2022-03-01 Nuvasive, Inc. Systems and methods for performing neurophysiologic monitoring during spine surgery
US9757067B1 (en) 2012-11-09 2017-09-12 Nuvasive, Inc. Systems and methods for performing neurophysiologic monitoring during spine surgery
KR101560373B1 (en) 2012-12-05 2015-10-15 김노을 electrode boiler with electrodes unit
US9757072B1 (en) 2013-02-11 2017-09-12 Nuvasive, Inc. Waveform marker placement algorithm for use in neurophysiologic monitoring
WO2014127217A1 (en) * 2013-02-15 2014-08-21 T4 Analytics Llc Electrode systems for use with medical monitoring systems
CA2906558A1 (en) * 2013-03-15 2014-09-25 Amit Rajguru Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US10098585B2 (en) 2013-03-15 2018-10-16 Cadwell Laboratories, Inc. Neuromonitoring systems and methods
US9867985B2 (en) 2014-03-24 2018-01-16 Bioness Inc. Systems and apparatus for gait modulation and methods of use
US10420480B1 (en) 2014-09-16 2019-09-24 Nuvasive, Inc. Systems and methods for performing neurophysiologic monitoring
EP3218046B1 (en) 2014-12-11 2024-04-17 Saluda Medical Pty Ltd Device and computer program for feedback control of neural stimulation
EP3957356A1 (en) 2015-04-09 2022-02-23 Saluda Medical Pty Limited Electrode to nerve distance estimation
CA3010880A1 (en) 2016-01-11 2017-07-20 Bioness Inc. Systems and apparatus for gait modulation and methods of use
JP7278076B2 (en) 2016-06-24 2023-05-19 サルーダ・メディカル・ピーティーワイ・リミテッド Nerve stimulation to reduce artifacts
EP3525670B1 (en) 2016-10-14 2022-09-14 Blink Device LLC Quantitative neuromusculature blockade sensing systems and methods
US10188346B2 (en) 2016-10-27 2019-01-29 Focal Wellness, Inc. Cubital tunnel infomatic monitor
US9808208B1 (en) * 2016-10-27 2017-11-07 Focal Wellness, Inc. Carpal tunnel infomatic monitor
US9935395B1 (en) 2017-01-23 2018-04-03 Cadwell Laboratories, Inc. Mass connection plate for electrical connectors
US10758801B1 (en) 2017-02-11 2020-09-01 Focal Wellness, Inc. Method and system for proper kicking technique
US10874347B1 (en) 2017-03-02 2020-12-29 Focal Wellness, Inc. Multiple plane sensors
US11051737B2 (en) * 2017-05-19 2021-07-06 Ricoh Company, Ltd. Biomagnetic measurement method, biomagnetic measuring device, and biomagnetic measuring system
KR102432861B1 (en) * 2017-06-15 2022-08-16 삼성전자주식회사 Image sensor for distance measuring
USD837394S1 (en) 2017-07-11 2019-01-01 Neurometrix, Inc. Transcutaneous electrical nerve stimulation (TENS) device
USD857910S1 (en) 2017-09-21 2019-08-27 Neurometrix, Inc. Transcutaneous electrical nerve stimulation device
USD865986S1 (en) 2017-09-21 2019-11-05 Neurometrix, Inc. Transcutaneous electrical nerve stimulation device strap
US11944820B2 (en) 2018-04-27 2024-04-02 Saluda Medical Pty Ltd Neurostimulation of mixed nerves
US11253182B2 (en) 2018-05-04 2022-02-22 Cadwell Laboratories, Inc. Apparatus and method for polyphasic multi-output constant-current and constant-voltage neurophysiological stimulation
USD861903S1 (en) 2018-05-15 2019-10-01 Neurometrix, Inc. Apparatus for transcutaneous electrical nerve stimulation
US11166648B2 (en) * 2018-05-24 2021-11-09 General Electric Company Method and system for estimating patient recovery time utilizing neuromuscular transmission measurements
US11443649B2 (en) 2018-06-29 2022-09-13 Cadwell Laboratories, Inc. Neurophysiological monitoring training simulator
US11612344B2 (en) 2018-11-02 2023-03-28 Biocircuit Technologies, Inc. Electrode-based systems and devices for interfacing with biological tissue and related methods
US11382564B2 (en) * 2018-12-28 2022-07-12 Jose Antonio Gamboa-Pinto Medical monitoring system with a foot diagnostic device
JP2022071585A (en) 2020-10-28 2022-05-16 キヤノン株式会社 Photoelectric conversion apparatus, photoelectric conversion system, and moving body

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3572322A (en) * 1968-10-11 1971-03-23 Hoffmann La Roche Transducer assembly
AT325196B (en) * 1971-12-01 1975-10-10 Rodler Ing Hans ELECTRICAL DIAGNOSTIC DEVICE
US4213467A (en) * 1978-08-11 1980-07-22 Harvard College, President And Fellows Monitoring myoelectric signals
US4291705A (en) * 1979-09-10 1981-09-29 The Regents Of The University Of California Neuromuscular block monitor
US4807643A (en) * 1982-08-16 1989-02-28 University Of Iowa Research Foundation Digital electroneurometer
FI73878C (en) * 1983-06-10 1987-12-10 Instrumentarium Oy FOERFARANDE FOER VIDAREUTVECKLING AV NERVMUSKELANSLUTNINGS MAETNING.
US4811742A (en) * 1985-06-11 1989-03-14 Verimed, Inc. Proportional response electrical muscle stimulation
US4763666A (en) * 1986-04-22 1988-08-16 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. Method and apparatus for determining the thermal sensitivity of the human peripheral nervous system
US5080099A (en) * 1988-08-26 1992-01-14 Cardiotronics, Inc. Multi-pad, multi-function electrode
US5099844A (en) * 1988-12-22 1992-03-31 Biofield Corp. Discriminant function analysis method and apparatus for disease diagnosis and screening
US5511553A (en) * 1989-02-15 1996-04-30 Segalowitz; Jacob Device-system and method for monitoring multiple physiological parameters (MMPP) continuously and simultaneously
US5050612A (en) * 1989-09-12 1991-09-24 Matsumura Kenneth N Device for computer-assisted monitoring of the body
DE3939790C1 (en) * 1989-12-01 1991-02-28 Draegerwerk Ag, 2400 Luebeck, De
NL9000983A (en) * 1990-04-24 1991-11-18 Univ Nijmegen APPARATUS AND METHOD FOR DETERMINING THE INFLUENCE OF ANESTHETICS ON HUMANS OR ANIMALS.
US5143081A (en) * 1990-07-27 1992-09-01 New York University Randomized double pulse stimulus and paired event analysis
US5131401A (en) * 1990-09-10 1992-07-21 Axon Medical Inc. Method and apparatus for monitoring neuromuscular blockage
US5092344A (en) * 1990-11-19 1992-03-03 Lee Tzium Shou Remote indicator for stimulator
US5255677A (en) * 1991-02-26 1993-10-26 Vickers Plc Disposable electrodes for electromyography (EMG) and nerve conduction velocity (NCV) and kit containing same
US5203330A (en) * 1991-02-26 1993-04-20 Vickers Plc Disposable electrodes for electromyography (EMG) and nerve conduction velocity (NCV) and kit containing same
US5215100A (en) * 1991-04-29 1993-06-01 Occupational Preventive Diagnostic, Inc. Nerve condition monitoring system and electrode supporting structure
FR2698008A1 (en) * 1992-11-13 1994-05-20 Mcadams Eric Multifunction device with multiple electrodes and use of this device.
US5379764A (en) * 1992-12-09 1995-01-10 Diasense, Inc. Non-invasive determination of analyte concentration in body of mammals
US5467768A (en) * 1993-03-17 1995-11-21 Nihon Koden Corporation Multi-purpose sensor
US5327902A (en) * 1993-05-14 1994-07-12 Lemmen Roger D Apparatus for use in nerve conduction studies
US5496363A (en) * 1993-06-02 1996-03-05 Minnesota Mining And Manufacturing Company Electrode and assembly
US5333618A (en) * 1993-06-30 1994-08-02 Gregory Lekhtman Portable self-contained instrument for the measurement of nerve resistance of a patient
US5560372A (en) * 1994-02-02 1996-10-01 Cory; Philip C. Non-invasive, peripheral nerve mapping device and method of use
US5540235A (en) * 1994-06-30 1996-07-30 Wilson; John R. Adaptor for neurophysiological monitoring with a personal computer
US6132386A (en) * 1997-07-01 2000-10-17 Neurometrix, Inc. Methods for the assessment of neuromuscular function by F-wave latency

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