CA2248189A1 - System for determining analyte concentration - Google Patents

System for determining analyte concentration

Info

Publication number
CA2248189A1
CA2248189A1 CA002248189A CA2248189A CA2248189A1 CA 2248189 A1 CA2248189 A1 CA 2248189A1 CA 002248189 A CA002248189 A CA 002248189A CA 2248189 A CA2248189 A CA 2248189A CA 2248189 A1 CA2248189 A1 CA 2248189A1
Authority
CA
Canada
Prior art keywords
analyte concentration
optical detection
determining analyte
detection system
fluorescence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002248189A
Other languages
French (fr)
Other versions
CA2248189C (en
Inventor
James N. Herron
Douglas A. Christensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Utah Research Foundation UURF
Original Assignee
University Of Utah Research Foundation
James N. Herron
Douglas A. Christensen
University Of Utah
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Utah Research Foundation, James N. Herron, Douglas A. Christensen, University Of Utah filed Critical University Of Utah Research Foundation
Priority claimed from PCT/US1997/004377 external-priority patent/WO1997035181A1/en
Publication of CA2248189A1 publication Critical patent/CA2248189A1/en
Application granted granted Critical
Publication of CA2248189C publication Critical patent/CA2248189C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings

Abstract

The present invention relates to a system (80) for determining analyte concentration. The system (80) includes an optical detection system (92) that detects fluorescence from fluorescent binding assays in a biosensor (88). A processing system (96) may be used to determine analyte concentration from the fluorescence detected by the optical detection system (92). The optical detection system (92) may include photodetectors with or without in series lenses.
Alternatively, a CCD camera (146) may be used.
CA002248189A 1996-03-19 1997-03-19 System for determining analyte concentration Expired - Lifetime CA2248189C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1368496P 1996-03-19 1996-03-19
US60/013,684 1996-03-19
PCT/US1997/004377 WO1997035181A1 (en) 1996-03-19 1997-03-19 System for determining analyte concentration

Publications (2)

Publication Number Publication Date
CA2248189A1 true CA2248189A1 (en) 1997-09-25
CA2248189C CA2248189C (en) 2007-05-29

Family

ID=38150711

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002248189A Expired - Lifetime CA2248189C (en) 1996-03-19 1997-03-19 System for determining analyte concentration

Country Status (1)

Country Link
CA (1) CA2248189C (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8300993B2 (en) 2009-03-02 2012-10-30 Mbio Diagnostics, Inc. Waveguide with integrated lens
US8331751B2 (en) 2009-03-02 2012-12-11 mBio Diagnositcs, Inc. Planar optical waveguide with core of low-index-of-refraction interrogation medium
US8586347B2 (en) 2010-09-15 2013-11-19 Mbio Diagnostics, Inc. System and method for detecting multiple molecules in one assay
US9658222B2 (en) 2009-03-02 2017-05-23 Mbio Diagnostics, Inc. Planar waveguide based cartridges and associated methods for detecting target analyte

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9212995B2 (en) 2009-03-02 2015-12-15 Mbio Diagnostics, Inc. System and method for detecting multiple molecules in one assay

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8300993B2 (en) 2009-03-02 2012-10-30 Mbio Diagnostics, Inc. Waveguide with integrated lens
US8331751B2 (en) 2009-03-02 2012-12-11 mBio Diagnositcs, Inc. Planar optical waveguide with core of low-index-of-refraction interrogation medium
US8606066B2 (en) 2009-03-02 2013-12-10 Mbio Diagnostics, Inc. Planar optical waveguide with core of low-index-of-refraction interrogation medium
US9658222B2 (en) 2009-03-02 2017-05-23 Mbio Diagnostics, Inc. Planar waveguide based cartridges and associated methods for detecting target analyte
US8586347B2 (en) 2010-09-15 2013-11-19 Mbio Diagnostics, Inc. System and method for detecting multiple molecules in one assay

Also Published As

Publication number Publication date
CA2248189C (en) 2007-05-29

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Legal Events

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EEER Examination request
MKEX Expiry

Effective date: 20170320