CA2246355C - Endovascular apparatus - Google Patents
Endovascular apparatus Download PDFInfo
- Publication number
- CA2246355C CA2246355C CA002246355A CA2246355A CA2246355C CA 2246355 C CA2246355 C CA 2246355C CA 002246355 A CA002246355 A CA 002246355A CA 2246355 A CA2246355 A CA 2246355A CA 2246355 C CA2246355 C CA 2246355C
- Authority
- CA
- Canada
- Prior art keywords
- sleeve
- hardening
- exterior
- conduit
- aneurysm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12027—Type of occlusion
- A61B17/1204—Type of occlusion temporary occlusion
- A61B17/12045—Type of occlusion temporary occlusion double occlusion, e.g. during anastomosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
- A61B17/12113—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
- A61B17/12118—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm for positioning in conjunction with a stent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00004—(bio)absorbable, (bio)resorbable, resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00535—Surgical instruments, devices or methods, e.g. tourniquets pneumatically or hydraulically operated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B2017/1205—Introduction devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B2017/12127—Double occlusion, e.g. for creating blood-free anastomosis site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/89—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/94—Stents retaining their form, i.e. not being deformable, after placement in the predetermined place
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/954—Instruments specially adapted for placement or removal of stents or stent-grafts for placing stents or stent-grafts in a bifurcation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2002/065—Y-shaped blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
- A61F2002/072—Encapsulated stents, e.g. wire or whole stent embedded in lining
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
- A61F2002/075—Stent-grafts the stent being loosely attached to the graft material, e.g. by stitching
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0003—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having an inflatable pocket filled with fluid, e.g. liquid or gas
Abstract
Percutaneous treatment of aortic aneurysms and like vascular anomalies by an apparatus and method wherein the apparatus is delivered via catheter and comprises a sleeve with at least one peripheral conduit which is caused to assume an expanded, rigid configuration by the introduction of a chemical or mechanical hardening means, whereby the sleeve is caused to assume an open cylindrical configuration for fluid flow therethrough.
Description
ENDOVASCULAR APPARATUS
Background of the Invention Field of the Invention The present invention relates to the percutaneous treatment of vessels by an apparatus and method wherein the apparatus is delivered via catheter and comprises a surgical graft which is fixated in a vessel by means of a chemical or mechanical hardening-filler material system.
General Backsround Previous methods of treating aortic aneurysms include treatment via surgical procedure in which an incision is made in the abdomen or chest of the patient, the diseased area is cleaned by the surgeon and an artificial graft is sutured in place.
This highly invasive procedure usually results in long hospital stays and lengthy recoveries. Further, mortality and morbidity complications often result as a consequence of this surgical procedure.
Other percutaneous methods have been attempted, such as are disclosed in U.S. Patent No. 4,577,631 (utilizing occlusion catheters with pressure sensitive adhesives), U.S. Patent No. 4,740,207 (self-expanding scent-type materials) and U.S.
Patents No. 4,271,839, 4,776,337 and 4,762,132 (other stem derived devices).
There still exists a need, however, for a simple method of repairing a vessel with an intravascular graft which allows normal tissue ingrowth to occur at the repair site. There exists a specific need for a percutaneous approach in which a catheter could be loaded with a surgical graft that can be fixated in a vessel such as the aorta.
Summary of the Invention The present invention provides devices for repairing aortic aneurysms and the like. The intraluminal graft of the present invention in one embodiment comprises a flexible linear or bifurcated tubular sleeve delivered to a repair site in a body by suitable means such as a catheter. The sleeve is suitably made of woven or cast material, and has peripheral conduits or tubes at each end. Each conduit has at least a single port that is connected to an elongated introduction means associated with the l catheter delivery means. The introduction means may be attached to the outer surface of the sleeve. The collapsed sleeve may be made rigid and circular by the introduction through the introduction means of a chemical or mechanical hardening means.
Background of the Invention Field of the Invention The present invention relates to the percutaneous treatment of vessels by an apparatus and method wherein the apparatus is delivered via catheter and comprises a surgical graft which is fixated in a vessel by means of a chemical or mechanical hardening-filler material system.
General Backsround Previous methods of treating aortic aneurysms include treatment via surgical procedure in which an incision is made in the abdomen or chest of the patient, the diseased area is cleaned by the surgeon and an artificial graft is sutured in place.
This highly invasive procedure usually results in long hospital stays and lengthy recoveries. Further, mortality and morbidity complications often result as a consequence of this surgical procedure.
Other percutaneous methods have been attempted, such as are disclosed in U.S. Patent No. 4,577,631 (utilizing occlusion catheters with pressure sensitive adhesives), U.S. Patent No. 4,740,207 (self-expanding scent-type materials) and U.S.
Patents No. 4,271,839, 4,776,337 and 4,762,132 (other stem derived devices).
There still exists a need, however, for a simple method of repairing a vessel with an intravascular graft which allows normal tissue ingrowth to occur at the repair site. There exists a specific need for a percutaneous approach in which a catheter could be loaded with a surgical graft that can be fixated in a vessel such as the aorta.
Summary of the Invention The present invention provides devices for repairing aortic aneurysms and the like. The intraluminal graft of the present invention in one embodiment comprises a flexible linear or bifurcated tubular sleeve delivered to a repair site in a body by suitable means such as a catheter. The sleeve is suitably made of woven or cast material, and has peripheral conduits or tubes at each end. Each conduit has at least a single port that is connected to an elongated introduction means associated with the l catheter delivery means. The introduction means may be attached to the outer surface of the sleeve. The collapsed sleeve may be made rigid and circular by the introduction through the introduction means of a chemical or mechanical hardening means.
-2-The chemical hardening means may be a polymeric material introduced through the introduction means through an external source, such as a catheter or syringe. Alternatively, the mechanical hardening means may comprise a single wire or multiple wires inserted into the conduits to support the ends, or any portion of the ' sleeve. The wires are not attached to the sleeve but reside in the conduits to provide a constant spring tension. The wires may be of any suitable material which retains its tension, such as spring wire or memory wire.
The introduction means may be detached from the sleeve after introduction of the chemical or mechanical hardening means.
The sleeve may alternatively be associated With a fixation means comprising either a series of cylindrical tubules or an enclosure which fits over the sleeve, with a hardening-filter system enclosed therein. The hardening-filler system includes an activatable hardening material which may be provided in the form of microspheres that upon external agitation may be disrupted, allowing the contents to IS react together and form a hardened material that fills the tubules or enclosure, thereby expanding and rigidifying the fixation means, and fixing the sleeve in place in the site of repair. Polymeric materials which are activatable include thioisocyanates, aldehydes, isocyanates, divinyl compounds, epoxides or acrylates. In addition to the aforementioned, photoactivatabie crossiinkable groups as succinimidyi azido salicylate, succinimidyl-azidobenzoate, succinimidyl dithio acetate, azidoiodobenzene, fluoro nitrophenylazide, salicylate azides, benzophenonc-maleimide, and the tike may be used as photoactivatable crosslinking reagents. The material may also consist of a thin coating which can be activated by external forces such as laser, radio frequency, ultrasound or the like, with the same hardening result taking place. These materials 2S would allow for normal tissue ingrowth to take place.
Brief Description of the Figures Figure 1 shows a perspective view of a vascular graft according to the present invention in a folded state prior to placement and expansion thereof;
Figure 2 shows a perspective view of the vascular graft in an expanded state by means of wires;
Figure 3 is a perspective view of the device as in Figure 2 showing the introduction of chemical hardening material via syringe;
WO 97/29716 PCTlUS97/02377
The introduction means may be detached from the sleeve after introduction of the chemical or mechanical hardening means.
The sleeve may alternatively be associated With a fixation means comprising either a series of cylindrical tubules or an enclosure which fits over the sleeve, with a hardening-filter system enclosed therein. The hardening-filler system includes an activatable hardening material which may be provided in the form of microspheres that upon external agitation may be disrupted, allowing the contents to IS react together and form a hardened material that fills the tubules or enclosure, thereby expanding and rigidifying the fixation means, and fixing the sleeve in place in the site of repair. Polymeric materials which are activatable include thioisocyanates, aldehydes, isocyanates, divinyl compounds, epoxides or acrylates. In addition to the aforementioned, photoactivatabie crossiinkable groups as succinimidyi azido salicylate, succinimidyl-azidobenzoate, succinimidyl dithio acetate, azidoiodobenzene, fluoro nitrophenylazide, salicylate azides, benzophenonc-maleimide, and the tike may be used as photoactivatable crosslinking reagents. The material may also consist of a thin coating which can be activated by external forces such as laser, radio frequency, ultrasound or the like, with the same hardening result taking place. These materials 2S would allow for normal tissue ingrowth to take place.
Brief Description of the Figures Figure 1 shows a perspective view of a vascular graft according to the present invention in a folded state prior to placement and expansion thereof;
Figure 2 shows a perspective view of the vascular graft in an expanded state by means of wires;
Figure 3 is a perspective view of the device as in Figure 2 showing the introduction of chemical hardening material via syringe;
WO 97/29716 PCTlUS97/02377
-3-Figure 4 is a perspective view of an alternate embodiment comprising a series of cylindrical tubules;
Figure 5 is a perspective view of an alternative embodiment of the device, where the vascular graft includes an enclosure which fits over the sleeve;
Figure G is an alternative embodiment of the present invention having a fluid track comprising a continuous cylindrical tubule which is helically wound around the proximal and distal ends of the sleeve;
Figures 7a and 7b represent an alternative embodiment comprising a bifurcated vascular graft including a dual guide wire delivery system;
Figures 8a through 8d show placement of a bifurcated vascular graft according to the present invention;
Figure 9 shows a further alternative embodiment of a vascular graft according to the present invention;
Figures IOa through lOc show filling of the cylindrical tubules after placement of the graft;
Figures lla through ,11d are fragmentary views of vascular grafts according to the present invention; and Figures 12a and 12b are cross sectional views of a vascular graft according to the present invention.
Detailed Description of the Invention The present invention provides a device and method for repairing an aneurysm or the like in a vessel, such as the aorta.
Referring to Figures 1 and 2, a vascular graft comprising a sleeve is shown generally at 10. Sleeve 10 is shown in a folded conformation in Figure 1 and in an expanded state in Figure 2. Sleeve 10 is either a flexible linear or bifurcated (as shown in Figures 7-12) tubular sleeve made of woven or extruded cast material.
Sleeve IO is made of a biocompatibie polymeric material. Fabrics from which sleeve 10 may be made are polyamides, such as nylon G, nylon G,G, and the like, Dacron~, polyesters, such as PET, polyethers, fluorinated polymers, such as polytetrafluoroethylene (PTFE), or biodegradable or nonbiodegradable fibers derived from natural sources such as carbohydrates, collagens, and proteins. The fabric may be of a woven knit, or solid structure. The most preferred materials are Dacron~ and PTFE. Sleeve IO is suitably
Figure 5 is a perspective view of an alternative embodiment of the device, where the vascular graft includes an enclosure which fits over the sleeve;
Figure G is an alternative embodiment of the present invention having a fluid track comprising a continuous cylindrical tubule which is helically wound around the proximal and distal ends of the sleeve;
Figures 7a and 7b represent an alternative embodiment comprising a bifurcated vascular graft including a dual guide wire delivery system;
Figures 8a through 8d show placement of a bifurcated vascular graft according to the present invention;
Figure 9 shows a further alternative embodiment of a vascular graft according to the present invention;
Figures IOa through lOc show filling of the cylindrical tubules after placement of the graft;
Figures lla through ,11d are fragmentary views of vascular grafts according to the present invention; and Figures 12a and 12b are cross sectional views of a vascular graft according to the present invention.
Detailed Description of the Invention The present invention provides a device and method for repairing an aneurysm or the like in a vessel, such as the aorta.
Referring to Figures 1 and 2, a vascular graft comprising a sleeve is shown generally at 10. Sleeve 10 is shown in a folded conformation in Figure 1 and in an expanded state in Figure 2. Sleeve 10 is either a flexible linear or bifurcated (as shown in Figures 7-12) tubular sleeve made of woven or extruded cast material.
Sleeve IO is made of a biocompatibie polymeric material. Fabrics from which sleeve 10 may be made are polyamides, such as nylon G, nylon G,G, and the like, Dacron~, polyesters, such as PET, polyethers, fluorinated polymers, such as polytetrafluoroethylene (PTFE), or biodegradable or nonbiodegradable fibers derived from natural sources such as carbohydrates, collagens, and proteins. The fabric may be of a woven knit, or solid structure. The most preferred materials are Dacron~ and PTFE. Sleeve IO is suitably
-4-delivered by a catheter. Catheters of polyurethan, PTFE, PVC silicone or the like with internal diameters of 1 to about 3mm are suitable for polymer injection.
Sleeve 10 has a proximal end 14, a distal end 16, an interior portion 18, an exterior portion 20 and peripheral circular conduits or tubes 22, 24 located one at each end 14, 16 respectively. Each conduit 22, 24 has at least one inlet port 26 and at least one outlet or exhaust port 28, inlets) 26 being connected to elongated introduction means 30, 32 respectively. Introduction means 30, 32 may be attached to exterior portion 20 of sleeve 10. Referring to Figure 2, collapsed sleeve 10 is expanded and made rigid by the insertion of a spring wire or wires 34, 36 inserted through introduction means 30, 32. A single wire or multiple wires may be inserted to support ends 14, 16, the center body or any portion of sleeve 10.
Wires 34, 36 are not attached to sleeve 10 but reside in introduction means 30, 32 or conduits 22, 24, providing a constant spring tension. The entrance tubing may be detached from the sleeve after placement of supporting wires 34, 36 in end tubes 22, 24.
The supporting wire may be made of stainless steel, spring steel, memory shape metals (such as nitinol, for example), titanium, or metal alloys of any kind, not limited to the aforementioned. Furthermore, the configuration of the supporting wire may be solid, braided or woven.
As shown in Figure 3, the graft may be expanded and made rigid and circular by a chemical hardening means introduced into a single spiral tube, or alternatively, as shown in Figure 4, a series of interconnected concentric cylindrical tubules 40 attached to and encasing the sleeve 10. Tubules 40 are interconnected by means of connecting tubes 41 extending between the tubules.
The chemical hardening means may be introduced in the form of an injectable polymeric material comprised of a one part system, a two part system, self expanding systems, thermosets, thermoplastics and the like. These polymers or polymeric systems would fill tubes 32 or tubules 40, causing them to expand and rigidify, thereby fixing the sleeve at the site of repair. This embodiment is of particular use for fusing such grafts in large vessels such as the aorta or pulmonary arteries.
Two part activatable hardening material may be supplied in the form of microspheres (not shown) that upon agitation by an external force may be disrupted. The external energy could originate from any suitable source including -4a-IR, visible or UV light through optic fiber on mechanical vibrational means from about 1 to 100,000 WO 97!29716 PCT/US97/02377
Sleeve 10 has a proximal end 14, a distal end 16, an interior portion 18, an exterior portion 20 and peripheral circular conduits or tubes 22, 24 located one at each end 14, 16 respectively. Each conduit 22, 24 has at least one inlet port 26 and at least one outlet or exhaust port 28, inlets) 26 being connected to elongated introduction means 30, 32 respectively. Introduction means 30, 32 may be attached to exterior portion 20 of sleeve 10. Referring to Figure 2, collapsed sleeve 10 is expanded and made rigid by the insertion of a spring wire or wires 34, 36 inserted through introduction means 30, 32. A single wire or multiple wires may be inserted to support ends 14, 16, the center body or any portion of sleeve 10.
Wires 34, 36 are not attached to sleeve 10 but reside in introduction means 30, 32 or conduits 22, 24, providing a constant spring tension. The entrance tubing may be detached from the sleeve after placement of supporting wires 34, 36 in end tubes 22, 24.
The supporting wire may be made of stainless steel, spring steel, memory shape metals (such as nitinol, for example), titanium, or metal alloys of any kind, not limited to the aforementioned. Furthermore, the configuration of the supporting wire may be solid, braided or woven.
As shown in Figure 3, the graft may be expanded and made rigid and circular by a chemical hardening means introduced into a single spiral tube, or alternatively, as shown in Figure 4, a series of interconnected concentric cylindrical tubules 40 attached to and encasing the sleeve 10. Tubules 40 are interconnected by means of connecting tubes 41 extending between the tubules.
The chemical hardening means may be introduced in the form of an injectable polymeric material comprised of a one part system, a two part system, self expanding systems, thermosets, thermoplastics and the like. These polymers or polymeric systems would fill tubes 32 or tubules 40, causing them to expand and rigidify, thereby fixing the sleeve at the site of repair. This embodiment is of particular use for fusing such grafts in large vessels such as the aorta or pulmonary arteries.
Two part activatable hardening material may be supplied in the form of microspheres (not shown) that upon agitation by an external force may be disrupted. The external energy could originate from any suitable source including -4a-IR, visible or UV light through optic fiber on mechanical vibrational means from about 1 to 100,000 WO 97!29716 PCT/US97/02377
-5-hertz supplied by mechanical or electrical transducers or by heat upon disruption of the microspheres, the activatable hardening material is liberated and allowed to harden.
Disruption of the microspheres releases the separated components, allowing the ' components to react together and form a hardened material that fills series of tubules 40 thereby fixing sleeve IO in place at the site of repair. Polymeric systems may be comprised of vinyl or divinyl compounds in which an initiator is contained in the microspheres, epoxies containing microencapsulated amine component, or diisocyanates with encapsulated amine or hydroxyl terminated prepolymers. Amino groups can be so isolated from methylacetimidate, ethyl acetimidate, dimethylgiutarimidate, dimethyl, adipidate, dimethyl sebaimidate, diisotltionyl propionimidatc, dimethyl oxydipropionimidatesuccinate bis-esters, disuccinimidyl tartarate, dicyanatobenzene, dichlorodinitrobenzene, adipaldehyde, glutaraldehyde and the like.
These hardening-filter systems would allow for normal tissue ingrowth in series of tubules 40 to take place. Because the tubules comprise only a small fraction of the total surface area of the sleeve, these hardening filling systems would allow for tissue ingrowth to take place into the sleeve material not impeded by the tubules, providing further reinforcement of the placement of the sleeve 10.
In a further embodiment shown in Figure 5, the material may be introduced by means of a hardening-filler system comprising an enclosure 50 attached to sleeve 10. Enclosure S0, like tubules 40, is filled with an activatable hardening material consisting of either a one-part polymer system, a two-part polymer system or a self expanding monomer, which upon polymerization would fill enclosure 50, causing it to expand and rigidify, thereby fixing sleeve IO at the site of repair. The activatable hardening material is described above with reference to Figure 4.
Referring now to Figure 6, an alternative embodiment of sleeve 10 is shown in place at a repair site G0. Sleeve 10 has a fluid track comprising a continuous cylindrical tubule 40 which is heIicaIly wound around proximal end 14 and distal end 16 of sleeve 10. Tubule 40 can be filled with a curing polymer selected from thermoset polymers or two part polymers, as described hereinabove. Sleeve 10 may optionally include supplemental physical attachment means (not shown) such as spikes, barbs or the like at proximal and distal ends 14,16.
Figures 7-9 represent an alternative embodiment comprising a bifurcated vascular graft l I0 including a dual guide wire delivery system I I2. Graft 110 has a
Disruption of the microspheres releases the separated components, allowing the ' components to react together and form a hardened material that fills series of tubules 40 thereby fixing sleeve IO in place at the site of repair. Polymeric systems may be comprised of vinyl or divinyl compounds in which an initiator is contained in the microspheres, epoxies containing microencapsulated amine component, or diisocyanates with encapsulated amine or hydroxyl terminated prepolymers. Amino groups can be so isolated from methylacetimidate, ethyl acetimidate, dimethylgiutarimidate, dimethyl, adipidate, dimethyl sebaimidate, diisotltionyl propionimidatc, dimethyl oxydipropionimidatesuccinate bis-esters, disuccinimidyl tartarate, dicyanatobenzene, dichlorodinitrobenzene, adipaldehyde, glutaraldehyde and the like.
These hardening-filter systems would allow for normal tissue ingrowth in series of tubules 40 to take place. Because the tubules comprise only a small fraction of the total surface area of the sleeve, these hardening filling systems would allow for tissue ingrowth to take place into the sleeve material not impeded by the tubules, providing further reinforcement of the placement of the sleeve 10.
In a further embodiment shown in Figure 5, the material may be introduced by means of a hardening-filler system comprising an enclosure 50 attached to sleeve 10. Enclosure S0, like tubules 40, is filled with an activatable hardening material consisting of either a one-part polymer system, a two-part polymer system or a self expanding monomer, which upon polymerization would fill enclosure 50, causing it to expand and rigidify, thereby fixing sleeve IO at the site of repair. The activatable hardening material is described above with reference to Figure 4.
Referring now to Figure 6, an alternative embodiment of sleeve 10 is shown in place at a repair site G0. Sleeve 10 has a fluid track comprising a continuous cylindrical tubule 40 which is heIicaIly wound around proximal end 14 and distal end 16 of sleeve 10. Tubule 40 can be filled with a curing polymer selected from thermoset polymers or two part polymers, as described hereinabove. Sleeve 10 may optionally include supplemental physical attachment means (not shown) such as spikes, barbs or the like at proximal and distal ends 14,16.
Figures 7-9 represent an alternative embodiment comprising a bifurcated vascular graft l I0 including a dual guide wire delivery system I I2. Graft 110 has a
6 PCT/US97/02377 _6_ proximal end 1 I4 and at least two distal ends 116, I I8. Figures 8a through 8d show placement of bifurcated vascular graft 1I0 at a repair site 160 where the vessel bifurcates. Graft I10 and delivery system 112 are advanced through a vessel to repair site I60. Delivery system 1 I2 includes guide wires 120, I22 whereby ends I
14, t 16,118 ' are placed at different branches of the vessel bifurcation. Figure 7b shows graft l I0 in place at site 160.
Figures 9-I2 show an alternative embodiment of a vascular graft according to the present invention, indicated generally at 2I0. Graft 210 has proximal and distal ends 214,216 and cylindrical tubule 240. Tubule 240 has a first end 242 and a second end 244, located near proximal end 214. After placement of graft 210, tubule 240 is filled.
Referring to Figures 10a, I0b and 10c, filling means 250 is shown.
Although filling means 250 is shown in conjunction with a tubular vascular graft, such a filling means may be used with any vascular graft according to the present invention.
Filling means 250 comprises casing 251, filling tube 252 with distal infusion inlet 254 and exhaust tube 256 with distal exhaust vent 258. Filling means 250 may be incorporated into the vascular graft delivery means or may alternatively be separate from but associated with the delivery means. Figure IOb is an enlarged fragmentary view of filling tube 252 which shows the manner in vyhich infusion inlet 254 connects to first end 242 of tubule 240, via pinch ring 262 located near the distal end of infusion inlet 254. Distal end of infusion inlet 254 is advanced into end 242 of tubule 240 until pinch ring 262 is inserted in tubule 240. As shown in Figure 10c, casing 251 of filling means 250 is advanced over end 242 of tubule 240 whereby pinch ring 262 creates an interference fit between filling tube 252 and end 242 of tubule 240. Exhaust vent 258 connects to end 244 of tubule 240 in the same manner.
Figures 11-12 show alternative embodiments of the inventive vascular graft. Figure l la shows a graft 310 having an outer layer 370 surrounding tubules 340.
Figure llb shows graft 310 having two outer layers 370,372 surrounding tubules 340.
Figure llc shows graft 410 having no outer layer over tubules 440, and lacking ' connection between tubule 440 and proximal coil 480. Figure lId shows a cross section of graft S I0, having an inner core 590. Figures 12a and 12b show a ' longitudinal cross section of graft 610 in place in repair site 660, wherein graft 610 has _'7 an enlarged proximal coil 680 located directly at proximal end 614 of graft 610, i.e. not more than about 5mm from proximal end 614.
The unique features of the device are the manner of its delivery and ' fixation at the site of repair, its low profile which may prevent interference with normal heart functions, and the non-invasive nature of the delivery which would reduce costs normally associated with closure of such a defect. The device and method of fixation provides a non-invasive treatment of aortic aneurysms and the like. The device is made of polymeric material and is delivered via catheter in a non-invasive procedure. In one embodiment, the device operates through chemical means to repair an aneurysm.
I0 Advantages of the apparatus and method of the present invention are many. No preformed stem is required and the apparatus has a smaller insertion diameter than previous vascular grafts. Further, the vascular graft has a lower cost of production than previous graft materials and procedures.
The practice of the present invention achieves several objectives and advantages. Currently, there are no percutaneous devices available to cure a septai defect or the like. The device and method of the present invention provides an advantage over surgery in that the cost of the procedure is substantially less, the risk of infection is less, the hospital residency time is Less and there is no physically deforming scar.
Further advantages include applicability to procedures such as repair of PDA, patent ductus anomaly. The non-invasive mode of delivery would reduce costs associated with this type of procedure. In addition, the low profile of the apparatus may minimize or prevent interference with normal heart functions.
While this invention may be embodied in many different forms, there are described in detail herein specific preferred embodiments of the invention.
This description is an exemplification of the principles of the invention and is not intended to limit the invention to the particular embodiments illustrated.
The above Examples and disclosure are intended to be illustrative and not exhaustive. These examples and description will suggest many variations and alternatives to one of ordinary skill in this art. All these alternatives and variations are intended to be included within the scope of the attached claims. Those familiar with the art may recognize other equivalents to the specific embodiments described herein which equivalents are also intended to be encompassed by the claims attached hereto.
14, t 16,118 ' are placed at different branches of the vessel bifurcation. Figure 7b shows graft l I0 in place at site 160.
Figures 9-I2 show an alternative embodiment of a vascular graft according to the present invention, indicated generally at 2I0. Graft 210 has proximal and distal ends 214,216 and cylindrical tubule 240. Tubule 240 has a first end 242 and a second end 244, located near proximal end 214. After placement of graft 210, tubule 240 is filled.
Referring to Figures 10a, I0b and 10c, filling means 250 is shown.
Although filling means 250 is shown in conjunction with a tubular vascular graft, such a filling means may be used with any vascular graft according to the present invention.
Filling means 250 comprises casing 251, filling tube 252 with distal infusion inlet 254 and exhaust tube 256 with distal exhaust vent 258. Filling means 250 may be incorporated into the vascular graft delivery means or may alternatively be separate from but associated with the delivery means. Figure IOb is an enlarged fragmentary view of filling tube 252 which shows the manner in vyhich infusion inlet 254 connects to first end 242 of tubule 240, via pinch ring 262 located near the distal end of infusion inlet 254. Distal end of infusion inlet 254 is advanced into end 242 of tubule 240 until pinch ring 262 is inserted in tubule 240. As shown in Figure 10c, casing 251 of filling means 250 is advanced over end 242 of tubule 240 whereby pinch ring 262 creates an interference fit between filling tube 252 and end 242 of tubule 240. Exhaust vent 258 connects to end 244 of tubule 240 in the same manner.
Figures 11-12 show alternative embodiments of the inventive vascular graft. Figure l la shows a graft 310 having an outer layer 370 surrounding tubules 340.
Figure llb shows graft 310 having two outer layers 370,372 surrounding tubules 340.
Figure llc shows graft 410 having no outer layer over tubules 440, and lacking ' connection between tubule 440 and proximal coil 480. Figure lId shows a cross section of graft S I0, having an inner core 590. Figures 12a and 12b show a ' longitudinal cross section of graft 610 in place in repair site 660, wherein graft 610 has _'7 an enlarged proximal coil 680 located directly at proximal end 614 of graft 610, i.e. not more than about 5mm from proximal end 614.
The unique features of the device are the manner of its delivery and ' fixation at the site of repair, its low profile which may prevent interference with normal heart functions, and the non-invasive nature of the delivery which would reduce costs normally associated with closure of such a defect. The device and method of fixation provides a non-invasive treatment of aortic aneurysms and the like. The device is made of polymeric material and is delivered via catheter in a non-invasive procedure. In one embodiment, the device operates through chemical means to repair an aneurysm.
I0 Advantages of the apparatus and method of the present invention are many. No preformed stem is required and the apparatus has a smaller insertion diameter than previous vascular grafts. Further, the vascular graft has a lower cost of production than previous graft materials and procedures.
The practice of the present invention achieves several objectives and advantages. Currently, there are no percutaneous devices available to cure a septai defect or the like. The device and method of the present invention provides an advantage over surgery in that the cost of the procedure is substantially less, the risk of infection is less, the hospital residency time is Less and there is no physically deforming scar.
Further advantages include applicability to procedures such as repair of PDA, patent ductus anomaly. The non-invasive mode of delivery would reduce costs associated with this type of procedure. In addition, the low profile of the apparatus may minimize or prevent interference with normal heart functions.
While this invention may be embodied in many different forms, there are described in detail herein specific preferred embodiments of the invention.
This description is an exemplification of the principles of the invention and is not intended to limit the invention to the particular embodiments illustrated.
The above Examples and disclosure are intended to be illustrative and not exhaustive. These examples and description will suggest many variations and alternatives to one of ordinary skill in this art. All these alternatives and variations are intended to be included within the scope of the attached claims. Those familiar with the art may recognize other equivalents to the specific embodiments described herein which equivalents are also intended to be encompassed by the claims attached hereto.
Claims (41)
PROPERTY OR PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:
1. A vascular graft apparatus comprising:
a) a flexible, tubular sleeve having at least onE; axis therethrough and further comprising a first end, at least one opposite end located opposite said first end, an interior portion and an exterior portion;
b) at least one exterior conduit attached to said sleeve, and surrounding and partially covering the exterior portion of said sleeve, said at least one exterior conduit having an inlet port;
c) delivery means removably connected to the at least one exterior conduit at its inlet port, said delivery means being in association with a hardening means;
whereby when the sleeve is delivered to an implant site at an area of a vessel having an aneurysm such that the apparatus is positioned at the aneurysm and the hardening means is delivered, the hardening means causes the at least one exterior conduit to assume an expanded, rigid configuration which fits securely into the vessel and is anchored thereto by pressure, causing the sleeve to be supported in an open condition for fluid flow therethrough.
a) a flexible, tubular sleeve having at least onE; axis therethrough and further comprising a first end, at least one opposite end located opposite said first end, an interior portion and an exterior portion;
b) at least one exterior conduit attached to said sleeve, and surrounding and partially covering the exterior portion of said sleeve, said at least one exterior conduit having an inlet port;
c) delivery means removably connected to the at least one exterior conduit at its inlet port, said delivery means being in association with a hardening means;
whereby when the sleeve is delivered to an implant site at an area of a vessel having an aneurysm such that the apparatus is positioned at the aneurysm and the hardening means is delivered, the hardening means causes the at least one exterior conduit to assume an expanded, rigid configuration which fits securely into the vessel and is anchored thereto by pressure, causing the sleeve to be supported in an open condition for fluid flow therethrough.
2. The apparatus of claim 1 further comprising at lease; one additional conduit surrounding the sleeve, said at least one additional conduit being located at the first end of the sleeve.
3. The apparatus of claim 1 wherein the at least one opposite end comprises at least two opposite ends located opposite said first end.
4. The apparatus of claim 1 further comprising a plurality of exterior conduits surrounding the sleeve, said exterior conduits being located between the first end and an opposite end of the sleeve.
5. The apparatus of claim 1 further comprising an enclosure over the exterior portion of the sleeve between the first end and an opposite end thereof.
6. The apparatus of claim 1 wherein:
a) the hardening means comprises at least one wire for insertion into and extension through an introduction means into said at least one exterior conduit.
a) the hardening means comprises at least one wire for insertion into and extension through an introduction means into said at least one exterior conduit.
7. The apparatus of claim 6 wherein the wire is made of a material selected from the group consisting of stainless steel, spring steel, memory shape metals, and metal alloys.
8. The system of claim 7 wherein the wire is made of nitinol.
9. The system of claim 7 wherein the wire is made of titanium.
10. The apparatus of claim 1 wherein the hardening means comprises an activatable hardening material selected from the group consisting of one-part polymer systems, two-part polymer systems and self-expanding monomers which, upon polymerization, fill said at least one exterior conduit, the apparatus further comprising a source of hardening material in association with the delivery means.
11. The apparatus of claim 10 wherein the hardening means further comprises at least one receptacle containing the activatable hardening material.
12. The apparatus of claim 11 further comprising a plurality of microspheres wherein the activatable hardening material is carried, said microspheres being located within the said at least one receptacle and further being constructed and arranged to release the activatable hardening material upon disruption of the plurality of microspheres, thereby allowing the activatable hardening material to harden.
13. The apparatus of claim 11 wherein the activatable hardening material comprises a first component and a second component, said first component and said second component being isolated from each other by said plurality of microspheres and carried in said plurality of microspheres, said plurality of microspheres being constructed and arranged to release said first and second components upon disruption of the plurality of microspheres, thereby allowing said first and second components to react and harden.
14. The apparatus of claim 1 wherein said at least one exterior conduit has an outlet port, whereby when the sleeve is delivered to an area of an artery having an aneurysm such that the apparatus is positioned at the aneurysm and hardening means is introduced, each said at least one exterior conduit is substantially filled with hardening means and is thereby caused to assume an expanded, rigid configuration which fits securely into the vessel and is anchored thereto by pressure, causing the sleeve to be supported in an open condition for fluid flow therethrough.
15. The apparatus of claim 14 comprising at least two exterior conduits surrounding the sleeve, one of said at least two exterior conduits being located proximal to the first end of the sleeve, and a second of said at least two conduits being located between the first end and an opposite end of the sleeve.
16. A system for repairing an arterial aneurysm, the system comprising:
a) a catheter delivery means; and b) an arterial graft apparatus comprising:
i) a flexible, tubular sleeve having at least one axis therethrough and further comprising a first end, at least one opposite end located opposite said first end, an interior portion and an exterior portion;
ii) at least one exterior conduit attached to said sleeve, and surrounding and partially covering the exterior portion of said sleeve, said at least one exterior conduit having at least one port;
iii) introduction means associated with the catheter delivery means and being in communication with said at least one port; and iv) hardening means delivered through said introduction means for causing the arterial graft device to assume a rigid cylindrical configuration;
whereby when the apparatus is delivered to an area of an artery having an aneurysm such that the sleeve is positioned at the aneurysm and hardening means is introduced, the conduits are caused to assume a rigid, expanded configuration which fits securely into the artery and is anchored thereto by pressure, causing the sleeve to be supported to an open condition for fluid flow therethrough, and causing the aneurysm to be repaired.
a) a catheter delivery means; and b) an arterial graft apparatus comprising:
i) a flexible, tubular sleeve having at least one axis therethrough and further comprising a first end, at least one opposite end located opposite said first end, an interior portion and an exterior portion;
ii) at least one exterior conduit attached to said sleeve, and surrounding and partially covering the exterior portion of said sleeve, said at least one exterior conduit having at least one port;
iii) introduction means associated with the catheter delivery means and being in communication with said at least one port; and iv) hardening means delivered through said introduction means for causing the arterial graft device to assume a rigid cylindrical configuration;
whereby when the apparatus is delivered to an area of an artery having an aneurysm such that the sleeve is positioned at the aneurysm and hardening means is introduced, the conduits are caused to assume a rigid, expanded configuration which fits securely into the artery and is anchored thereto by pressure, causing the sleeve to be supported to an open condition for fluid flow therethrough, and causing the aneurysm to be repaired.
17. The system of claim 16 wherein the sleeve is made of a nonbiodegradable, biocompatible polymeric material.
18. The system of claim 17 wherein the polymeric material is selected from the group consisting of thermosetting polymer, thermoplastic polymers, thermoplastic elastomers, elastomers, composites, pseudo-thermoplastics, carbohydrates, proteins, and mixtures thereof.
19. The system of claim 16 wherein the sleeve is made of a material selected from the group consisting of Dacron~ or PTFE.
20. The system of claim 16 wherein the sleeve is made: of a woven or braided material.
21. The system of claim 16 wherein the sleeve is made of a material selected from the group consisting of polyamides, nylon 6, nylon 6,6, polyesters, PET, polyethers, fluorinated polymers, polytetrafluoroethylene, biodegradable or nonbiodegradable fibers derived from natural sources such as carbohydrates, collagens, and proteins, and mixtures thereof.
22. The system of claim 16 wherein the sleeve is biodegradable.
23. The system of claim 16 wherein:
a) the hardening means comprises at least one wire for insertion into and extension through the introduction means into an exterior conduit.
a) the hardening means comprises at least one wire for insertion into and extension through the introduction means into an exterior conduit.
24. The system of claim 23 wherein the wire is made: of a material selected from the group consisting of stainless steel, spring steel, memory shape metals, and metal alloys.
25. The system of claim 24 wherein the wire is made of nitinol.
26. The system of claim 24 wherein the wire is made of titanium.
27. The system of claim 16 wherein the peripheral conduit has an inlet port and an exhaust port and wherein the hardening means is a polymeric material.
28. The system of claim 27 wherein the polymeric material is introduced through the introduction means via an external source.
29. The system of claim 2g wherein the external source is a syringe.
30. The system of claim 28 wherein the external source is a catheter.
31. The system of claim 16 wherein the hardening means comprises an activatable hardening material selected from the group consisting of one-part polymer systems, two-part polymer systems and self-expanding monomers.
32. The system of claim 31 wherein the hardening means further comprises a plurality of microspheres wherein the activatable hardening material is carried, said microspheres being constructed and arranged to release the activatable hardening material upon disruption, thereby allowing the activatable hardening material to harden.
33. The system of claim 32 wherein the activatable hardening material comprises a first component and a second component isolated from each other by and carried in said plurality of microspheres, said plurality of microspheres being constructed and arranged to release said first and second components upon disruption, thereby allowing the components to react and harden.
34. A vascular graft apparatus, comprising:
a) a flexible, tubular sleeve having at least one axis therethrough and further comprising a first end, at least one opposite end located opposite said first end, and an exterior portion;
b) at least one exterior conduit surrounding and partially covering said sleeve, each said at least one exterior conduit having an inlet port;
c) delivery means removably connected to at least one exterior conduit at its inlet port, said delivery means being in association with a hardening means, said hardening means comprising an activatable hardening material selected from the group consisting of one-part polymer systems, two-part polymer systems and self-expanding monomers which, upon polymerization, fill said at least one exterior conduit, the apparatus further comprising a source of hardening material in association with the delivery means;
whereby when the sleeve is delivered to an implant site at an area of a vessel having an aneurysm such that the apparatus is positioned at the aneurysm and the hardening means is delivered, the hardening means causes the at least one exterior conduit to assume an expanded, rigid configuration which fits securely into the vessel and is anchored thereto by pressure, causing the sleeve to be supported in an open condition for fluid flow therethrough.
a) a flexible, tubular sleeve having at least one axis therethrough and further comprising a first end, at least one opposite end located opposite said first end, and an exterior portion;
b) at least one exterior conduit surrounding and partially covering said sleeve, each said at least one exterior conduit having an inlet port;
c) delivery means removably connected to at least one exterior conduit at its inlet port, said delivery means being in association with a hardening means, said hardening means comprising an activatable hardening material selected from the group consisting of one-part polymer systems, two-part polymer systems and self-expanding monomers which, upon polymerization, fill said at least one exterior conduit, the apparatus further comprising a source of hardening material in association with the delivery means;
whereby when the sleeve is delivered to an implant site at an area of a vessel having an aneurysm such that the apparatus is positioned at the aneurysm and the hardening means is delivered, the hardening means causes the at least one exterior conduit to assume an expanded, rigid configuration which fits securely into the vessel and is anchored thereto by pressure, causing the sleeve to be supported in an open condition for fluid flow therethrough.
35. The apparatus of claim 34 wherein the hardening means further comprises at least one receptacle containing the activatable hardening material.
36. A vascular graft apparatus, comprising:
a) a flexible, tubular sleeve having at least one axis therethrough and further comprising a first end, at least one opposite end located opposite said first end, and an exterior portion;
b) at least one exterior conduit surrounding and partially covering said sleeve, each said at least one exterior conduit having an inlet port;
c) delivery means removably connected to at least one exterior conduit at its inlet port;
d) hardening means in association with the delivery means, said hardening means comprising an activatable hardening material selected from the group consisting of one-part polymer systems, two-part polymer systems and self-expanding monomers, said hardening means further comprising at least one receptacle containing the activatable hardening material, the apparatus further comprising a plurality of microspheres wherein the activatable hardening material is carried, said plurality of microspheres being located within said at least one receptacle and further being constructed and arranged to release the activatable hardening material upon disruption of the plurality of microspheres, thereby allowing the activatable hardening material to harden, said apparatus further comprising a source of hardening material in association with the delivery means;
whereby when the sleeve is delivered to an implant site at an area of a vessel having an aneurysm such that the apparatus is positioned at the aneurysm and the hardening means is delivered, the hardening means causes the at least one exterior conduit to assume an expanded, rigid configuration which fits securely into the vessel and is anchored thereto by pressure, causing the sleeve to be supported in an open condition for fluid flow therethrough.
a) a flexible, tubular sleeve having at least one axis therethrough and further comprising a first end, at least one opposite end located opposite said first end, and an exterior portion;
b) at least one exterior conduit surrounding and partially covering said sleeve, each said at least one exterior conduit having an inlet port;
c) delivery means removably connected to at least one exterior conduit at its inlet port;
d) hardening means in association with the delivery means, said hardening means comprising an activatable hardening material selected from the group consisting of one-part polymer systems, two-part polymer systems and self-expanding monomers, said hardening means further comprising at least one receptacle containing the activatable hardening material, the apparatus further comprising a plurality of microspheres wherein the activatable hardening material is carried, said plurality of microspheres being located within said at least one receptacle and further being constructed and arranged to release the activatable hardening material upon disruption of the plurality of microspheres, thereby allowing the activatable hardening material to harden, said apparatus further comprising a source of hardening material in association with the delivery means;
whereby when the sleeve is delivered to an implant site at an area of a vessel having an aneurysm such that the apparatus is positioned at the aneurysm and the hardening means is delivered, the hardening means causes the at least one exterior conduit to assume an expanded, rigid configuration which fits securely into the vessel and is anchored thereto by pressure, causing the sleeve to be supported in an open condition for fluid flow therethrough.
37. A vascular graft apparatus, comprising:
a) a flexible, tubular sleeve having at least one axis therethrough and further comprising a first end, at least one opposite end located opposite said first end, and an exterior portion;
b) at least one exterior conduit surrounding and partially covering said sleeve, each said at least one exterior conduit having an inlet port;
c) delivery means removably connected to at least one exterior conduit at its inlet port;
d) hardening means in association with the delivery means, said hardening means comprising an activatable hardening material selected from the group consisting of one-part polymer systems, two-part polymer systems and self-expanding monomers, said hardening means further comprising at least one receptacle containing the activatable hardening material, the apparatus further comprising a plurality of microspheres and wherein the activatable hardening material comprises a first component and a second component, said first component and said second component being isolated from each other by said plurality of microspheres and carried in said plurality of microspheres, said plurality of microspheres being constructed and arranged to release said first component and said second component upon disruption of the plurality of microspheres, thereby allowing said first component and said second component to react and harden, said apparatus further comprising a source of hardening material in association with the delivery means;
whereby when the sleeve is delivered to an implant site at an area of a vessel having an aneurysm such that the apparatus is positioned at the aneurysm and the hardening means is delivered, the hardening means causes the at least one exterior conduit to assume an expanded, rigid configuration which fits securely into the vessel and is anchored thereto by pressure, causing the sleeve to be supported in an open condition for fluid flow therethrough.
a) a flexible, tubular sleeve having at least one axis therethrough and further comprising a first end, at least one opposite end located opposite said first end, and an exterior portion;
b) at least one exterior conduit surrounding and partially covering said sleeve, each said at least one exterior conduit having an inlet port;
c) delivery means removably connected to at least one exterior conduit at its inlet port;
d) hardening means in association with the delivery means, said hardening means comprising an activatable hardening material selected from the group consisting of one-part polymer systems, two-part polymer systems and self-expanding monomers, said hardening means further comprising at least one receptacle containing the activatable hardening material, the apparatus further comprising a plurality of microspheres and wherein the activatable hardening material comprises a first component and a second component, said first component and said second component being isolated from each other by said plurality of microspheres and carried in said plurality of microspheres, said plurality of microspheres being constructed and arranged to release said first component and said second component upon disruption of the plurality of microspheres, thereby allowing said first component and said second component to react and harden, said apparatus further comprising a source of hardening material in association with the delivery means;
whereby when the sleeve is delivered to an implant site at an area of a vessel having an aneurysm such that the apparatus is positioned at the aneurysm and the hardening means is delivered, the hardening means causes the at least one exterior conduit to assume an expanded, rigid configuration which fits securely into the vessel and is anchored thereto by pressure, causing the sleeve to be supported in an open condition for fluid flow therethrough.
38. The apparatus of claim 34 wherein each said at least one exterior conduit has an outlet port, whereby when the sleeve is delivered to an area of any artery having an aneurysm such that the apparatus is positioned at the aneurysm and hardening means is introduced, each said at least one exterior conduit is substantially filled with hardening means and is thereby caused to assume an expanded, rigid configuration which fits securely into the vessel and is anchored thereto by pressure, causing the sleeve to be supported in an open condition for fluid flow therethrough.
39. The apparatus of claim 38 comprising at least two exterior conduits surrounding the sleeve, one of said at least two exterior conduits being located proximal to the first end of the sleeve, and a second of said at least two conduits being located between the first end an opposite end of the sleeve.
40. A vascular graft apparatus comprising:
a) a flexible, tubular sleeve having at least one axis therethrough and further comprising a first end, at least one second end, an interior portion and an exterior portion;
b) an exterior conduit attached to said sleeve, and surrounding and partially covering the exterior portion of said sleeve at the first end and said at least one second end, said exterior conduit having at least one entrance port, said exterior conduit being adjacent to the exterior portion of the sleeve;
c) introduction means in communication with the at least one entrance port of each exterior conduit for introduction of a hardening means;
whereby when the sleeve is delivered to an area of an artery having an aneurysm such that the sleeve is positioned at the aneurysm, and the hardening means is introduced, each said exterior conduit is caused to assume an expanded, rigid configuration which fits securely into the artery and is anchored thereto by pressure, causing the sleeve to be supported in an open condition for fluid flow therethrough.
a) a flexible, tubular sleeve having at least one axis therethrough and further comprising a first end, at least one second end, an interior portion and an exterior portion;
b) an exterior conduit attached to said sleeve, and surrounding and partially covering the exterior portion of said sleeve at the first end and said at least one second end, said exterior conduit having at least one entrance port, said exterior conduit being adjacent to the exterior portion of the sleeve;
c) introduction means in communication with the at least one entrance port of each exterior conduit for introduction of a hardening means;
whereby when the sleeve is delivered to an area of an artery having an aneurysm such that the sleeve is positioned at the aneurysm, and the hardening means is introduced, each said exterior conduit is caused to assume an expanded, rigid configuration which fits securely into the artery and is anchored thereto by pressure, causing the sleeve to be supported in an open condition for fluid flow therethrough.
41. A vascular graft apparatus comprising:
a) a flexible, tubular sleeve having at least one axis therethrough and further comprising a first end, at least two opposite ends located opposite said first end, and an exterior portion;
b) at least one exterior conduit attached to said sleeve, and surrounding and partially covering the exterior portion of said sleeve, each said at least one exterior conduit having an inlet port, said at least one exterior conduit being adjacent to the exterior portion of the sleeve;
c) delivery means removably connected to the at least one exterior conduit at its inlet port, said delivery means being in association with a hardening means;
whereby when the sleeve is delivered to an implant site at an area of a vessel having an aneurysm such that the apparatus is positioned at the aneurysm, and the hardening means is delivered, the hardening means causes the at least one exterior conduit to assume an expanded, rigid configuration which fits securely into the vessel and is anchored thereto by pressure, causing the sleeve to be supported in an open condition for fluid flow therethrough.
a) a flexible, tubular sleeve having at least one axis therethrough and further comprising a first end, at least two opposite ends located opposite said first end, and an exterior portion;
b) at least one exterior conduit attached to said sleeve, and surrounding and partially covering the exterior portion of said sleeve, each said at least one exterior conduit having an inlet port, said at least one exterior conduit being adjacent to the exterior portion of the sleeve;
c) delivery means removably connected to the at least one exterior conduit at its inlet port, said delivery means being in association with a hardening means;
whereby when the sleeve is delivered to an implant site at an area of a vessel having an aneurysm such that the apparatus is positioned at the aneurysm, and the hardening means is delivered, the hardening means causes the at least one exterior conduit to assume an expanded, rigid configuration which fits securely into the vessel and is anchored thereto by pressure, causing the sleeve to be supported in an open condition for fluid flow therethrough.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002420638A CA2420638C (en) | 1996-02-13 | 1997-02-13 | Endovascular apparatus |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/600,834 | 1996-02-13 | ||
US08/600,834 US5871537A (en) | 1996-02-13 | 1996-02-13 | Endovascular apparatus |
PCT/US1997/002377 WO1997029716A1 (en) | 1996-02-13 | 1997-02-13 | Endovascular apparatus |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002420638A Division CA2420638C (en) | 1996-02-13 | 1997-02-13 | Endovascular apparatus |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2246355A1 CA2246355A1 (en) | 1997-08-21 |
CA2246355C true CA2246355C (en) | 2003-04-29 |
Family
ID=24405224
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002246355A Expired - Fee Related CA2246355C (en) | 1996-02-13 | 1997-02-13 | Endovascular apparatus |
Country Status (5)
Country | Link |
---|---|
US (10) | US5871537A (en) |
EP (1) | EP0959810B1 (en) |
AT (1) | ATE552799T1 (en) |
CA (1) | CA2246355C (en) |
WO (1) | WO1997029716A1 (en) |
Families Citing this family (242)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6039749A (en) | 1994-02-10 | 2000-03-21 | Endovascular Systems, Inc. | Method and apparatus for deploying non-circular stents and graftstent complexes |
US6451047B2 (en) | 1995-03-10 | 2002-09-17 | Impra, Inc. | Encapsulated intraluminal stent-graft and methods of making same |
US6053943A (en) * | 1995-12-08 | 2000-04-25 | Impra, Inc. | Endoluminal graft with integral structural support and method for making same |
US6264684B1 (en) | 1995-03-10 | 2001-07-24 | Impra, Inc., A Subsidiary Of C.R. Bard, Inc. | Helically supported graft |
US5871537A (en) * | 1996-02-13 | 1999-02-16 | Scimed Life Systems, Inc. | Endovascular apparatus |
US6692483B2 (en) | 1996-11-04 | 2004-02-17 | Advanced Stent Technologies, Inc. | Catheter with attached flexible side sheath |
US6325826B1 (en) * | 1998-01-14 | 2001-12-04 | Advanced Stent Technologies, Inc. | Extendible stent apparatus |
US7220275B2 (en) * | 1996-11-04 | 2007-05-22 | Advanced Stent Technologies, Inc. | Stent with protruding branch portion for bifurcated vessels |
US6835203B1 (en) * | 1996-11-04 | 2004-12-28 | Advanced Stent Technologies, Inc. | Extendible stent apparatus |
US7591846B2 (en) * | 1996-11-04 | 2009-09-22 | Boston Scientific Scimed, Inc. | Methods for deploying stents in bifurcations |
US6599316B2 (en) * | 1996-11-04 | 2003-07-29 | Advanced Stent Technologies, Inc. | Extendible stent apparatus |
US8211167B2 (en) | 1999-12-06 | 2012-07-03 | Boston Scientific Scimed, Inc. | Method of using a catheter with attached flexible side sheath |
ATE539702T1 (en) * | 1996-11-04 | 2012-01-15 | Advanced Stent Tech Inc | DEVICE FOR EXPANDING A STENT AND METHOD FOR DEPLOYING IT |
US6551350B1 (en) * | 1996-12-23 | 2003-04-22 | Gore Enterprise Holdings, Inc. | Kink resistant bifurcated prosthesis |
US6951572B1 (en) * | 1997-02-20 | 2005-10-04 | Endologix, Inc. | Bifurcated vascular graft and method and apparatus for deploying same |
US5995958A (en) * | 1997-03-04 | 1999-11-30 | Xu; Kevin Houzhi | System and method for storing and managing functions |
US6936057B1 (en) * | 1997-05-19 | 2005-08-30 | Cardio Medical Solutions, Inc. (Cms) | Device and method for partially occluding blood vessels using flow-through balloon |
GB9713624D0 (en) * | 1997-06-28 | 1997-09-03 | Anson Medical Ltd | Expandable device |
US6070589A (en) | 1997-08-01 | 2000-06-06 | Teramed, Inc. | Methods for deploying bypass graft stents |
WO1999023955A1 (en) * | 1997-11-12 | 1999-05-20 | Robert Lazzara | Vascular shunt apparatus |
US6395019B2 (en) * | 1998-02-09 | 2002-05-28 | Trivascular, Inc. | Endovascular graft |
US6241741B1 (en) | 1998-03-09 | 2001-06-05 | Corvascular Surgical Systems, Inc. | Anastomosis device and method |
ES2243050T3 (en) * | 1998-03-09 | 2005-11-16 | Ethicon, Inc. | ANASTOMOSIS DEVICE. |
US6290731B1 (en) | 1998-03-30 | 2001-09-18 | Cordis Corporation | Aortic graft having a precursor gasket for repairing an abdominal aortic aneurysm |
US6656215B1 (en) * | 2000-11-16 | 2003-12-02 | Cordis Corporation | Stent graft having an improved means for attaching a stent to a graft |
US6544253B1 (en) * | 1998-07-24 | 2003-04-08 | Eva Corporation | Surgical support device and method of using the same |
US6358276B1 (en) * | 1998-09-30 | 2002-03-19 | Impra, Inc. | Fluid containing endoluminal stent |
US6660030B2 (en) | 1998-12-11 | 2003-12-09 | Endologix, Inc. | Bifurcation graft deployment catheter |
US7655030B2 (en) | 2003-07-18 | 2010-02-02 | Boston Scientific Scimed, Inc. | Catheter balloon systems and methods |
US20050060027A1 (en) * | 1999-01-13 | 2005-03-17 | Advanced Stent Technologies, Inc. | Catheter balloon systems and methods |
US6350277B1 (en) * | 1999-01-15 | 2002-02-26 | Scimed Life Systems, Inc. | Stents with temporary retaining bands |
US6398803B1 (en) | 1999-02-02 | 2002-06-04 | Impra, Inc., A Subsidiary Of C.R. Bard, Inc. | Partial encapsulation of stents |
GB9904722D0 (en) * | 1999-03-03 | 1999-04-21 | Murch Clifford R | A tubular intraluminal graft |
US6261316B1 (en) | 1999-03-11 | 2001-07-17 | Endologix, Inc. | Single puncture bifurcation graft deployment system |
US8034100B2 (en) * | 1999-03-11 | 2011-10-11 | Endologix, Inc. | Graft deployment system |
US7387639B2 (en) * | 1999-06-04 | 2008-06-17 | Advanced Stent Technologies, Inc. | Short sleeve stent delivery catheter and methods |
WO2001001868A1 (en) | 1999-07-02 | 2001-01-11 | Quickpass, Inc. | Suturing device |
WO2001017435A1 (en) * | 1999-09-07 | 2001-03-15 | Microvena Corporation | Retrievable septal defect closure device |
US6312462B1 (en) | 1999-09-22 | 2001-11-06 | Impra, Inc. | Prosthesis for abdominal aortic aneurysm repair |
US6689156B1 (en) * | 1999-09-23 | 2004-02-10 | Advanced Stent Technologies, Inc. | Stent range transducers and methods of use |
US6443979B1 (en) * | 1999-12-20 | 2002-09-03 | Advanced Cardiovascular Systems, Inc. | Expandable stent delivery sheath and method of use |
US6355063B1 (en) * | 2000-01-20 | 2002-03-12 | Impra, Inc. | Expanded PTFE drug delivery graft |
AU2001233098A1 (en) * | 2000-01-27 | 2001-08-07 | Sterilis, Inc. | Cavity enlarger method and apparatus |
PT1259192E (en) | 2000-03-03 | 2004-04-30 | Cook Inc | ENDOVASCULAR DEVICE WITH A ENDOPROTESE |
US6551344B2 (en) * | 2000-04-26 | 2003-04-22 | Ev3 Inc. | Septal defect occluder |
US6729356B1 (en) | 2000-04-27 | 2004-05-04 | Endovascular Technologies, Inc. | Endovascular graft for providing a seal with vasculature |
US6658288B1 (en) | 2000-05-05 | 2003-12-02 | Endovascular Technologies, Inc. | Apparatus and method for aiding thrombosis through the application of electric potential |
US6440152B1 (en) | 2000-07-28 | 2002-08-27 | Microvena Corporation | Defect occluder release assembly and method |
US20020082684A1 (en) * | 2000-09-25 | 2002-06-27 | David Mishaly | Intravascular prosthetic and method |
US6695833B1 (en) * | 2000-09-27 | 2004-02-24 | Nellix, Inc. | Vascular stent-graft apparatus and forming method |
EP1333787B1 (en) * | 2000-11-15 | 2009-12-23 | Endologix, Inc. | Implantable vascular graft |
US7314483B2 (en) * | 2000-11-16 | 2008-01-01 | Cordis Corp. | Stent graft with branch leg |
US6579308B1 (en) * | 2000-11-28 | 2003-06-17 | Scimed Life Systems, Inc. | Stent devices with detachable distal or proximal wires |
NL1017672C2 (en) * | 2001-03-22 | 2002-09-24 | Hendrik Glastra | Implantable assembly with therapeutic effect. |
US6602269B2 (en) | 2001-03-30 | 2003-08-05 | Scimed Life Systems | Embolic devices capable of in-situ reinforcement |
US8617231B2 (en) | 2001-05-18 | 2013-12-31 | Boston Scientific Scimed, Inc. | Dual guidewire exchange catheter system |
GB0114918D0 (en) * | 2001-06-19 | 2001-08-08 | Vortex Innovation Ltd | Devices for repairing aneurysms |
US8101196B2 (en) | 2001-06-26 | 2012-01-24 | Biointeractions, Ltd. | Polysaccharide biomaterials and methods of use thereof |
US6994722B2 (en) * | 2001-07-03 | 2006-02-07 | Scimed Life Systems, Inc. | Implant having improved fixation to a body lumen and method for implanting the same |
FR2826863B1 (en) | 2001-07-04 | 2003-09-26 | Jacques Seguin | ASSEMBLY FOR PLACING A PROSTHETIC VALVE IN A BODY CONDUIT |
US20030100945A1 (en) * | 2001-11-23 | 2003-05-29 | Mindguard Ltd. | Implantable intraluminal device and method of using same in treating aneurysms |
US7288105B2 (en) | 2001-08-01 | 2007-10-30 | Ev3 Endovascular, Inc. | Tissue opening occluder |
JP4043210B2 (en) * | 2001-10-09 | 2008-02-06 | オリンパス株式会社 | Stent |
US7192441B2 (en) * | 2001-10-16 | 2007-03-20 | Scimed Life Systems, Inc. | Aortic artery aneurysm endovascular prosthesis |
AUPR847201A0 (en) * | 2001-10-26 | 2001-11-15 | Cook Incorporated | Endoluminal graft |
US20060292206A1 (en) * | 2001-11-26 | 2006-12-28 | Kim Steven W | Devices and methods for treatment of vascular aneurysms |
US7147661B2 (en) * | 2001-12-20 | 2006-12-12 | Boston Scientific Santa Rosa Corp. | Radially expandable stent |
AUPR969201A0 (en) * | 2001-12-20 | 2002-01-24 | White, Geoffrey H. | A device for use in intraluminal grafting |
DE60235723D1 (en) * | 2001-12-20 | 2010-04-29 | Trivascular Inc | METHOD AND DEVICE FOR PRODUCING AN ENDOVASCULAR TRANSPLANT SECTION |
US20100016943A1 (en) | 2001-12-20 | 2010-01-21 | Trivascular2, Inc. | Method of delivering advanced endovascular graft |
US7147660B2 (en) * | 2001-12-20 | 2006-12-12 | Boston Scientific Santa Rosa Corp. | Advanced endovascular graft |
US7125464B2 (en) | 2001-12-20 | 2006-10-24 | Boston Scientific Santa Rosa Corp. | Method for manufacturing an endovascular graft section |
US7326237B2 (en) * | 2002-01-08 | 2008-02-05 | Cordis Corporation | Supra-renal anchoring prosthesis |
US7122048B2 (en) * | 2002-05-03 | 2006-10-17 | Scimed Life Systems, Inc. | Hypotube endoluminal device |
US20050065596A1 (en) * | 2002-07-24 | 2005-03-24 | Xufan Tseng | Stents capable of controllably releasing histone deacetylase inhibitors |
EP1539291A4 (en) * | 2002-09-20 | 2010-03-10 | Flowmedica Inc | Method and apparatus for selective material delivery via an intra-renal catheter |
WO2004026183A2 (en) | 2002-09-20 | 2004-04-01 | Nellix, Inc. | Stent-graft with positioning anchor |
US7481821B2 (en) | 2002-11-12 | 2009-01-27 | Thomas J. Fogarty | Embolization device and a method of using the same |
US6887266B2 (en) * | 2002-11-14 | 2005-05-03 | Synecor, Llc | Endoprostheses and methods of manufacture |
WO2004060214A1 (en) * | 2002-12-30 | 2004-07-22 | Morsi Hesham | Endovascular balloon graft |
US7857748B2 (en) * | 2003-01-15 | 2010-12-28 | Syne Cor, Llc | Photocurable endoprosthesis methods of manufacture |
US20040143342A1 (en) * | 2003-01-16 | 2004-07-22 | Stack Richard S. | Satiation pouches and methods of use |
WO2004069055A2 (en) * | 2003-02-04 | 2004-08-19 | Ev3 Sunnyvale Inc. | Patent foramen ovale closure system |
US20040260382A1 (en) | 2003-02-12 | 2004-12-23 | Fogarty Thomas J. | Intravascular implants and methods of using the same |
US7438712B2 (en) * | 2003-03-05 | 2008-10-21 | Scimed Life Systems, Inc. | Multi-braid exterior tube |
US7150758B2 (en) * | 2003-03-06 | 2006-12-19 | Boston Scientific Santa Rosa Corp. | Kink resistant endovascular graft |
US7951557B2 (en) * | 2003-04-27 | 2011-05-31 | Protalix Ltd. | Human lysosomal proteins from plant cell culture |
US20100196345A1 (en) * | 2003-04-27 | 2010-08-05 | Protalix | Production of high mannose proteins in plant culture |
US6994723B1 (en) | 2003-05-21 | 2006-02-07 | Advanced Cardiovascular Systems, Inc. | Medical device made from self-stiffening composite |
US7632291B2 (en) * | 2003-06-13 | 2009-12-15 | Trivascular2, Inc. | Inflatable implant |
WO2005009523A1 (en) * | 2003-07-18 | 2005-02-03 | Boston Scientific Limited | Medical devices |
US20050015110A1 (en) | 2003-07-18 | 2005-01-20 | Fogarty Thomas J. | Embolization device and a method of using the same |
US8721710B2 (en) * | 2003-08-11 | 2014-05-13 | Hdh Medical Ltd. | Anastomosis system and method |
US8298280B2 (en) * | 2003-08-21 | 2012-10-30 | Boston Scientific Scimed, Inc. | Stent with protruding branch portion for bifurcated vessels |
WO2005037138A2 (en) * | 2003-10-14 | 2005-04-28 | Peacock James C Iii | Aneurysm treatment system and method |
US7344557B2 (en) * | 2003-11-12 | 2008-03-18 | Advanced Stent Technologies, Inc. | Catheter balloon systems and methods |
US8157855B2 (en) * | 2003-12-05 | 2012-04-17 | Boston Scientific Scimed, Inc. | Detachable segment stent |
US7803178B2 (en) | 2004-01-30 | 2010-09-28 | Trivascular, Inc. | Inflatable porous implants and methods for drug delivery |
US20050187568A1 (en) * | 2004-02-20 | 2005-08-25 | Klenk Alan R. | Devices and methods for closing a patent foramen ovale with a coil-shaped closure device |
US7641686B2 (en) * | 2004-04-23 | 2010-01-05 | Direct Flow Medical, Inc. | Percutaneous heart valve with stentless support |
US8012201B2 (en) | 2004-05-05 | 2011-09-06 | Direct Flow Medical, Inc. | Translumenally implantable heart valve with multiple chamber formed in place support |
GB0415152D0 (en) * | 2004-07-06 | 2004-08-11 | Anson Medical Ltd | Interconnected tubular structures |
US8048145B2 (en) | 2004-07-22 | 2011-11-01 | Endologix, Inc. | Graft systems having filling structures supported by scaffolds and methods for their use |
US8403955B2 (en) * | 2004-09-02 | 2013-03-26 | Lifescreen Sciences Llc | Inflatable intravascular filter |
US20060058892A1 (en) * | 2004-09-16 | 2006-03-16 | Lesh Michael D | Valved tissue augmentation implant |
US7641688B2 (en) | 2004-09-16 | 2010-01-05 | Evera Medical, Inc. | Tissue augmentation device |
US7244270B2 (en) * | 2004-09-16 | 2007-07-17 | Evera Medical | Systems and devices for soft tissue augmentation |
WO2006034077A1 (en) * | 2004-09-16 | 2006-03-30 | Juva Medical, Inc. | Tissue augmentation device |
US20060058890A1 (en) * | 2004-09-16 | 2006-03-16 | Lesh Michael D | Methods for soft tissue augmentation |
US20060058891A1 (en) * | 2004-09-16 | 2006-03-16 | Lesh Michael D | Transformable tissue bulking device |
US20060074481A1 (en) * | 2004-10-04 | 2006-04-06 | Gil Vardi | Graft including expandable cuff |
US20070179600A1 (en) * | 2004-10-04 | 2007-08-02 | Gil Vardi | Stent graft including expandable cuff |
US8048144B2 (en) * | 2004-11-30 | 2011-11-01 | Scimed Life Systems, Inc. | Prosthesis fixation device and method |
US7588596B2 (en) * | 2004-12-29 | 2009-09-15 | Scimed Life Systems, Inc. | Endoluminal prosthesis adapted to resist migration and method of deploying the same |
US20060149364A1 (en) * | 2004-12-31 | 2006-07-06 | Steven Walak | Low profile vascular graft |
US8945169B2 (en) * | 2005-03-15 | 2015-02-03 | Cook Medical Technologies Llc | Embolic protection device |
US20060222596A1 (en) | 2005-04-01 | 2006-10-05 | Trivascular, Inc. | Non-degradable, low swelling, water soluble radiopaque hydrogel polymer |
US8568477B2 (en) * | 2005-06-07 | 2013-10-29 | Direct Flow Medical, Inc. | Stentless aortic valve replacement with high radial strength |
EP1909655A2 (en) | 2005-06-20 | 2008-04-16 | Sutura, Inc. | Method and apparatus for applying a knot to a suture |
US7666220B2 (en) * | 2005-07-07 | 2010-02-23 | Nellix, Inc. | System and methods for endovascular aneurysm treatment |
US20070038292A1 (en) * | 2005-08-09 | 2007-02-15 | Moise Danielpour | Bio-absorbable stent |
US7731741B2 (en) * | 2005-09-08 | 2010-06-08 | Boston Scientific Scimed, Inc. | Inflatable bifurcation stent |
US8192477B2 (en) * | 2005-11-14 | 2012-06-05 | Boston Scientific Scimed, Inc. | Twisting bifurcation delivery system |
US20070150041A1 (en) * | 2005-12-22 | 2007-06-28 | Nellix, Inc. | Methods and systems for aneurysm treatment using filling structures |
US8821561B2 (en) * | 2006-02-22 | 2014-09-02 | Boston Scientific Scimed, Inc. | Marker arrangement for bifurcation catheter |
US8828091B2 (en) * | 2006-03-23 | 2014-09-09 | Boston Scientific Scimed, Inc. | Movable stent reinforcement |
US7481836B2 (en) * | 2006-03-30 | 2009-01-27 | Medtronic Vascular, Inc. | Prosthesis with coupling zone and methods |
US9585743B2 (en) | 2006-07-31 | 2017-03-07 | Edwards Lifesciences Cardiaq Llc | Surgical implant devices and methods for their manufacture and use |
WO2008016578A2 (en) * | 2006-07-31 | 2008-02-07 | Cartledge Richard G | Sealable endovascular implants and methods for their use |
US9408607B2 (en) | 2009-07-02 | 2016-08-09 | Edwards Lifesciences Cardiaq Llc | Surgical implant devices and methods for their manufacture and use |
US8216297B2 (en) * | 2006-08-14 | 2012-07-10 | Trivascular, Inc. | Dual chamber cuff structure |
US20080071343A1 (en) * | 2006-09-15 | 2008-03-20 | Kevin John Mayberry | Multi-segmented graft deployment system |
US7935144B2 (en) | 2006-10-19 | 2011-05-03 | Direct Flow Medical, Inc. | Profile reduction of valve implant |
US8133213B2 (en) * | 2006-10-19 | 2012-03-13 | Direct Flow Medical, Inc. | Catheter guidance through a calcified aortic valve |
US7655034B2 (en) * | 2006-11-14 | 2010-02-02 | Medtronic Vascular, Inc. | Stent-graft with anchoring pins |
US8523931B2 (en) * | 2007-01-12 | 2013-09-03 | Endologix, Inc. | Dual concentric guidewire and methods of bifurcated graft deployment |
WO2008111073A2 (en) | 2007-03-15 | 2008-09-18 | Bioprotect Ltd. | Prosthetic devices and methods for using same |
US20080228259A1 (en) * | 2007-03-16 | 2008-09-18 | Jack Fa-De Chu | Endovascular devices and methods to protect aneurysmal wall |
US20080234809A1 (en) * | 2007-03-23 | 2008-09-25 | Medtronic Vascular, Inc. | Stent Graft System With Injection Tube |
JP5411125B2 (en) | 2007-03-29 | 2014-02-12 | ノーブルズ メディカル テクノロジーズ、インコーポレイテッド | Suture device and system for closing a patent foramen ovale |
US20080262590A1 (en) * | 2007-04-19 | 2008-10-23 | Medtronic Vascular, Inc. | Delivery System for Stent-Graft |
EP3366762B1 (en) * | 2007-05-07 | 2020-07-08 | Protalix Ltd. | Large scale disposable bioreactor |
US8435283B2 (en) * | 2007-06-13 | 2013-05-07 | Boston Scientific Scimed, Inc. | Anti-migration features and geometry for a shape memory polymer stent |
JP2009000276A (en) | 2007-06-21 | 2009-01-08 | Olympus Medical Systems Corp | Medical tube, medical instrument, stent set and endoscope device |
US9814611B2 (en) | 2007-07-31 | 2017-11-14 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US9566178B2 (en) | 2010-06-24 | 2017-02-14 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US8486134B2 (en) | 2007-08-01 | 2013-07-16 | Boston Scientific Scimed, Inc. | Bifurcation treatment system and methods |
US20090088836A1 (en) | 2007-08-23 | 2009-04-02 | Direct Flow Medical, Inc. | Translumenally implantable heart valve with formed in place support |
US20090082841A1 (en) * | 2007-09-26 | 2009-03-26 | Boston Scientific Corporation | Apparatus for securing stent barbs |
US8066755B2 (en) * | 2007-09-26 | 2011-11-29 | Trivascular, Inc. | System and method of pivoted stent deployment |
US8663309B2 (en) * | 2007-09-26 | 2014-03-04 | Trivascular, Inc. | Asymmetric stent apparatus and method |
US8226701B2 (en) | 2007-09-26 | 2012-07-24 | Trivascular, Inc. | Stent and delivery system for deployment thereof |
US20090082845A1 (en) * | 2007-09-26 | 2009-03-26 | Boston Scientific Corporation | Alignment stent apparatus and method |
EP2194921B1 (en) * | 2007-10-04 | 2018-08-29 | TriVascular, Inc. | Modular vascular graft for low profile percutaneous delivery |
US8328861B2 (en) | 2007-11-16 | 2012-12-11 | Trivascular, Inc. | Delivery system and method for bifurcated graft |
US8083789B2 (en) * | 2007-11-16 | 2011-12-27 | Trivascular, Inc. | Securement assembly and method for expandable endovascular device |
US20100331958A1 (en) * | 2007-12-20 | 2010-12-30 | Trivascular, Inc. | Hinged endovascular device |
US8747456B2 (en) * | 2007-12-31 | 2014-06-10 | Boston Scientific Scimed, Inc. | Bifurcation stent delivery system and methods |
US20090198329A1 (en) | 2008-02-01 | 2009-08-06 | Kesten Randy J | Breast implant with internal flow dampening |
US20090198331A1 (en) * | 2008-02-01 | 2009-08-06 | Kesten Randy J | Implantable prosthesis with open cell flow regulation |
WO2009105699A1 (en) | 2008-02-22 | 2009-08-27 | Endologix, Inc. | Design and method of placement of a graft or graft system |
US8196279B2 (en) * | 2008-02-27 | 2012-06-12 | C. R. Bard, Inc. | Stent-graft covering process |
US8236040B2 (en) | 2008-04-11 | 2012-08-07 | Endologix, Inc. | Bifurcated graft deployment systems and methods |
AU2009240419A1 (en) | 2008-04-25 | 2009-10-29 | Nellix, Inc. | Stent graft delivery system |
EP2291125B1 (en) | 2008-05-09 | 2021-04-21 | Nobles Medical Technologies, Inc. | Suturing devices for suturing an anatomic valve |
US8377108B2 (en) | 2008-06-02 | 2013-02-19 | Boston Scientific Scimed, Inc. | Staggered two balloon bifurcation catheter assembly and methods |
CA2726596A1 (en) * | 2008-06-04 | 2009-12-10 | Nellix, Inc. | Sealing apparatus and methods of use |
JP5662310B2 (en) * | 2008-06-05 | 2015-01-28 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | Shrinkable branch device and method of manufacturing the same |
WO2009149405A1 (en) * | 2008-06-05 | 2009-12-10 | Boston Scientific Scimed, Inc. | Balloon bifurcated lumen treatment |
EP2520320B1 (en) | 2008-07-01 | 2016-11-02 | Endologix, Inc. | Catheter system |
US20100010518A1 (en) * | 2008-07-09 | 2010-01-14 | Joshua Stopek | Anastomosis Sheath And Method Of Use |
US8454680B2 (en) * | 2008-07-10 | 2013-06-04 | Atrial Systems, Llc | Endovascular conduit device with low profile occlusion members |
US8454679B2 (en) * | 2008-07-10 | 2013-06-04 | Atrial Systems, Llc | Endovascular conduit device for increasing safety of cardiac lead extraction and other vascular procedures |
USD853560S1 (en) | 2008-10-09 | 2019-07-09 | Nuvasive, Inc. | Spinal implant insertion device |
EP2349080B1 (en) | 2008-10-22 | 2016-04-13 | Boston Scientific Scimed, Inc. | Shape memory tubular stent with grooves |
US8905961B2 (en) * | 2008-12-19 | 2014-12-09 | St. Jude Medical, Inc. | Systems, apparatuses, and methods for cardiovascular conduits and connectors |
US9566146B2 (en) * | 2008-12-19 | 2017-02-14 | St. Jude Medical, Inc. | Cardiovascular valve and valve housing apparatuses and systems |
US8728012B2 (en) * | 2008-12-19 | 2014-05-20 | St. Jude Medical, Inc. | Apparatus and method for measuring blood vessels |
US20100160939A1 (en) * | 2008-12-19 | 2010-06-24 | St. Jude Medical, Inc. | Systems, apparatuses, and methods for cardiovascular cutting devices and valves |
EP2429452B1 (en) | 2009-04-28 | 2020-01-15 | Endologix, Inc. | Endoluminal prosthesis system |
JP2012525239A (en) | 2009-05-01 | 2012-10-22 | エンドロジックス、インク | Transcutaneous methods and devices for treating dissociation (priority information and incorporation by reference) |
US10772717B2 (en) | 2009-05-01 | 2020-09-15 | Endologix, Inc. | Percutaneous method and device to treat dissections |
EP2453940A2 (en) * | 2009-07-13 | 2012-05-23 | Yissum Research Development Company of The Hebrew University of Jerusalem | Intraluminal polymeric devices for the treatment of aneurysms |
WO2011008989A2 (en) | 2009-07-15 | 2011-01-20 | Endologix, Inc. | Stent graft |
WO2011017123A2 (en) | 2009-07-27 | 2011-02-10 | Endologix, Inc. | Stent graft |
US20110130756A1 (en) * | 2009-12-01 | 2011-06-02 | Everson Jr David C | Vasculature device |
US20110276078A1 (en) | 2009-12-30 | 2011-11-10 | Nellix, Inc. | Filling structure for a graft system and methods of use |
US20110218609A1 (en) * | 2010-02-10 | 2011-09-08 | Trivascular, Inc. | Fill tube manifold and delivery methods for endovascular graft |
US20110218617A1 (en) * | 2010-03-02 | 2011-09-08 | Endologix, Inc. | Endoluminal vascular prosthesis |
US8454682B2 (en) | 2010-04-13 | 2013-06-04 | Medtronic Vascular, Inc. | Anchor pin stent-graft delivery system |
US9433501B2 (en) | 2010-05-19 | 2016-09-06 | Direct Flow Medical, Inc. | Inflation media for implants |
US9603708B2 (en) | 2010-05-19 | 2017-03-28 | Dfm, Llc | Low crossing profile delivery catheter for cardiovascular prosthetic implant |
US8696738B2 (en) * | 2010-05-20 | 2014-04-15 | Maquet Cardiovascular Llc | Composite prosthesis with external polymeric support structure and methods of manufacturing the same |
US8979824B2 (en) | 2010-06-21 | 2015-03-17 | Boston Scientific Scimed, Inc. | Stent delivery system having retention structure |
US8808348B2 (en) * | 2010-06-23 | 2014-08-19 | Boston Scientific Scimed, Inc. | Delivery system having stent retention structure |
US20120109279A1 (en) | 2010-11-02 | 2012-05-03 | Endologix, Inc. | Apparatus and method of placement of a graft or graft system |
US20120191174A1 (en) | 2010-11-16 | 2012-07-26 | Trivascular, Inc. | Advanced endovascular graft and delivery system |
WO2012068298A1 (en) | 2010-11-17 | 2012-05-24 | Endologix, Inc. | Devices and methods to treat vascular dissections |
US8801768B2 (en) | 2011-01-21 | 2014-08-12 | Endologix, Inc. | Graft systems having semi-permeable filling structures and methods for their use |
EP2680915B1 (en) | 2011-03-01 | 2021-12-22 | Endologix LLC | Catheter system |
WO2012139054A1 (en) | 2011-04-06 | 2012-10-11 | Endologix, Inc. | Method and system for endovascular aneurysm treatment |
EP3644194B1 (en) | 2011-04-15 | 2022-12-07 | Heartstitch, Inc. | Suturing devices for suturing an anatomic valve |
US8978448B2 (en) | 2011-10-11 | 2015-03-17 | Trivascular, Inc. | In vitro testing of endovascular device |
WO2013057566A2 (en) | 2011-10-18 | 2013-04-25 | Ortho-Space Ltd. | Prosthetic devices and methods for using same |
US9827093B2 (en) | 2011-10-21 | 2017-11-28 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US8992595B2 (en) | 2012-04-04 | 2015-03-31 | Trivascular, Inc. | Durable stent graft with tapered struts and stable delivery methods and devices |
US9498363B2 (en) | 2012-04-06 | 2016-11-22 | Trivascular, Inc. | Delivery catheter for endovascular device |
US9445897B2 (en) | 2012-05-01 | 2016-09-20 | Direct Flow Medical, Inc. | Prosthetic implant delivery device with introducer catheter |
EP2852332B1 (en) | 2012-05-11 | 2019-06-26 | Heartstitch, Inc. | Suturing devices for suturing an anatomic structure |
WO2013177591A1 (en) * | 2012-05-25 | 2013-11-28 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Vascular anastomosis stent |
US10130346B2 (en) * | 2012-07-24 | 2018-11-20 | Omrix Biopharmaceuticals Ltd. | Device and method for the application of a curable fluid composition to a bodily organ |
US9358042B2 (en) * | 2013-03-13 | 2016-06-07 | The Spectranetics Corporation | Expandable member for perforation occlusion |
BR112015022688B1 (en) | 2013-03-14 | 2020-10-06 | Endologix, Inc. | METHOD FOR FORMING A MATERIAL IN SITU THROUGH INCREASING THE VOLUME OF AN EXPANDABLE MEMBER OF A MEDICAL DEVICE |
JP6431534B2 (en) | 2013-07-02 | 2018-11-28 | メッド − ベンチャー インベストメンツ、エルエルシー | Suture device and method for suturing anatomic tissue |
EP3079602B1 (en) | 2013-12-06 | 2020-01-22 | Med-venture Investments, LLC | Suturing apparatuses |
EP3834774A1 (en) * | 2014-05-30 | 2021-06-16 | Endologix LLC | Modular stent graft systems with inflatable fill structures |
US10178993B2 (en) | 2014-07-11 | 2019-01-15 | Cardio Medical Solutions, Inc. | Device and method for assisting end-to-side anastomosis |
US9782561B2 (en) | 2014-10-09 | 2017-10-10 | Vacular Solutions, Inc. | Catheter tip |
US9636477B2 (en) | 2014-10-09 | 2017-05-02 | Vascular Solutions, Inc. | Catheter |
JP6672286B2 (en) | 2014-10-23 | 2020-03-25 | トリバスキュラー・インコーポレイテッドTriVascular, INC. | Stent graft delivery system with access conduit |
RU2580168C1 (en) * | 2015-02-20 | 2016-04-10 | Игорь Валерьевич Михайлов | Article for formation of stent and method for formation thereof |
DE102015104338A1 (en) | 2015-03-23 | 2016-09-29 | Sitevasc Ug | Tubular sleeve and system for the atraumatic treatment of hollow organs |
CN112426253A (en) | 2015-05-27 | 2021-03-02 | 特里瓦斯库拉尔公司 | Balloon assisted endoluminal prosthesis deployment |
CN107624056B (en) | 2015-06-30 | 2020-06-09 | 恩朵罗杰克斯股份有限公司 | Locking assembly and related system and method |
EP3328326A4 (en) | 2015-07-30 | 2019-03-20 | TriVascular, Inc. | Endoluminal prosthesis deployment devices and methods |
WO2017046647A1 (en) | 2015-09-18 | 2017-03-23 | Ortho-Space Ltd. | Intramedullary fixated subacromial spacers |
CN105395297B (en) * | 2015-12-25 | 2016-11-30 | 李雷 | Intravascular stent and conveying sacculus, implant system |
WO2017180092A1 (en) | 2016-04-11 | 2017-10-19 | Nobles Medical Technologies Ii, Inc. | Suture spools for tissue suturing device |
US11406522B2 (en) * | 2016-11-09 | 2022-08-09 | Boston Scientific Scimed, Inc. | Deployable sleeves and related methods |
EP3573806A4 (en) | 2017-01-30 | 2019-12-11 | Ortho-Space Ltd. | Processing machine and methods for processing dip-molded articles |
US11839370B2 (en) | 2017-06-19 | 2023-12-12 | Heartstitch, Inc. | Suturing devices and methods for suturing an opening in the apex of the heart |
EP4115818A3 (en) | 2017-06-19 | 2023-04-05 | Heartstitch, Inc. | Suturing systems and methods for suturing body tissue |
WO2019035095A1 (en) | 2017-08-18 | 2019-02-21 | Nobles Medical Technologies Ii, Inc. | Apparatus for applying a knot to a suture |
US10709556B2 (en) * | 2017-08-24 | 2020-07-14 | Medtronic Vascular, Inc. | Transcatheter prosthesis with sealing component, and systems and methods for delivering and deployment thereof |
US10722351B2 (en) | 2017-08-24 | 2020-07-28 | Medtronic Vascular, Inc. | Transcatheter prosthesis with sealing component, and systems and methods for delivering and deployment thereof |
US10238834B2 (en) | 2017-08-25 | 2019-03-26 | Teleflex Innovations S.À.R.L. | Catheter |
DE102018103618A1 (en) * | 2018-02-19 | 2019-08-22 | Boris Vestweber | stent |
WO2020191203A1 (en) | 2019-03-20 | 2020-09-24 | inQB8 Medical Technologies, LLC | Aortic dissection implant |
EP3922217A1 (en) | 2020-06-05 | 2021-12-15 | BVS - Best Vascular Solutions GmbH | Tubular non-woven structure as an active substance carrier for atraumatic treatment of hollow organs and a method for its production |
DE102020117801A1 (en) | 2020-06-05 | 2021-12-09 | Bvs - Best Vascular Solutions Gmbh | Tubular fleece structure as an active substance carrier for the atraumatic treatment of hollow organs and a method for production |
DE102022122630A1 (en) | 2022-07-22 | 2024-01-25 | Bvs - Best Vascular Solutions Gmbh | Balloon catheter device for the atraumatic treatment of hollow organs and a method for producing such a balloon catheter device |
WO2024018082A1 (en) | 2022-07-22 | 2024-01-25 | Bvs - Best Vascular Solutions Gmbh | Balloon catheter device for atraumatic expansion of hollow organs, and a method for producing such a balloon catheter device |
Family Cites Families (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US414364A (en) * | 1889-11-05 | Vest-adjuster | ||
US448332A (en) * | 1891-03-17 | Horse hay-rake | ||
US581537A (en) * | 1897-04-27 | Necktie-fastener | ||
US3631854A (en) | 1969-05-19 | 1972-01-04 | Robert Howard Fryer | Inflatable medical assemblies |
US3991767A (en) * | 1973-11-02 | 1976-11-16 | Cutter Laboratories, Inc. | Tubular unit with vessel engaging cuff structure |
DE2714810A1 (en) | 1976-04-05 | 1977-10-13 | Anvar | PROCESS FOR MANUFACTURING ORGAN DENTALS PRODUCED ACCORDING TO THE PROCESS |
US4140126A (en) * | 1977-02-18 | 1979-02-20 | Choudhury M Hasan | Method for performing aneurysm repair |
US4141364A (en) * | 1977-03-18 | 1979-02-27 | Jorge Schultze | Expandable endotracheal or urethral tube |
US4183102A (en) * | 1977-09-08 | 1980-01-15 | Jacques Guiset | Inflatable prosthetic device for lining a body duct |
SE424045B (en) * | 1979-01-12 | 1982-06-28 | Tesi Ab | CATHETER |
US4271839A (en) * | 1979-07-25 | 1981-06-09 | Thomas J. Fogarty | Dilation catheter method and apparatus |
US4483332A (en) | 1983-01-03 | 1984-11-20 | Bruce Rind | Construction and method for forming an orthopedic cast and method of producing the construction |
US4580568A (en) * | 1984-10-01 | 1986-04-08 | Cook, Incorporated | Percutaneous endovascular stent and method for insertion thereof |
US4577631A (en) * | 1984-11-16 | 1986-03-25 | Kreamer Jeffry W | Aneurysm repair apparatus and method |
FR2580818B1 (en) * | 1985-04-19 | 1987-06-05 | Labo Electronique Physique | APPARATUS FOR EXAMINING MEDIA BY ULTRASONIC ECHOGRAPHY |
US4871365A (en) * | 1985-04-25 | 1989-10-03 | American Cyanamid Company | Partially absorbable prosthetic tubular article having an external support |
US4733665C2 (en) * | 1985-11-07 | 2002-01-29 | Expandable Grafts Partnership | Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft |
US4741872A (en) * | 1986-05-16 | 1988-05-03 | The University Of Kentucky Research Foundation | Preparation of biodegradable microspheres useful as carriers for macromolecules |
US4740207A (en) * | 1986-09-10 | 1988-04-26 | Kreamer Jeffry W | Intralumenal graft |
GB8807026D0 (en) * | 1988-03-24 | 1988-04-27 | Sheffield City Council | Bone fixation |
DE68922497T2 (en) * | 1988-08-24 | 1995-09-14 | Marvin J Slepian | ENDOLUMINAL SEAL WITH BISDEGRADABLE POLYMERS. |
US5328471A (en) | 1990-02-26 | 1994-07-12 | Endoluminal Therapeutics, Inc. | Method and apparatus for treatment of focal disease in hollow tubular organs and other tissue lumens |
GB8927282D0 (en) * | 1989-12-01 | 1990-01-31 | Univ Strathclyde | Vascular surgical devices |
ATE120377T1 (en) | 1990-02-08 | 1995-04-15 | Howmedica | INFLATABLE DILATATOR. |
US5123917A (en) * | 1990-04-27 | 1992-06-23 | Lee Peter Y | Expandable intraluminal vascular graft |
US5415634A (en) * | 1990-08-23 | 1995-05-16 | Devices For Vascular Intervention, Inc. | Catheter having helical inflation lumen |
DE9117152U1 (en) * | 1990-10-09 | 1996-07-11 | Cook Inc | Stent |
US5156620A (en) * | 1991-02-04 | 1992-10-20 | Pigott John P | Intraluminal graft/stent and balloon catheter for insertion thereof |
DE4104702C2 (en) * | 1991-02-15 | 1996-01-18 | Malte Neuss | Implants for organ pathways in spiral form |
CA2074304C (en) * | 1991-08-02 | 1996-11-26 | Cyril J. Schweich, Jr. | Drug delivery catheter |
US5320100A (en) | 1991-09-16 | 1994-06-14 | Atrium Medical Corporation | Implantable prosthetic device having integral patency diagnostic indicia |
US5151105A (en) * | 1991-10-07 | 1992-09-29 | Kwan Gett Clifford | Collapsible vessel sleeve implant |
US5336178A (en) * | 1992-11-02 | 1994-08-09 | Localmed, Inc. | Intravascular catheter with infusion array |
US5370691A (en) * | 1993-01-26 | 1994-12-06 | Target Therapeutics, Inc. | Intravascular inflatable stent |
US5334201A (en) * | 1993-03-12 | 1994-08-02 | Cowan Kevin P | Permanent stent made of a cross linkable material |
NL9300500A (en) | 1993-03-22 | 1994-10-17 | Industrial Res Bv | Expandable hollow sleeve for locally supporting and / or strengthening a body vessel, as well as a method for manufacturing it. |
US5411549A (en) | 1993-07-13 | 1995-05-02 | Scimed Life Systems, Inc. | Selectively expandable, retractable and removable stent |
WO1995008289A2 (en) | 1993-09-16 | 1995-03-30 | Scimed Life Systems, Inc. | Percutaneous repair of cardiovascular anomalies and repair compositions |
US5443495A (en) | 1993-09-17 | 1995-08-22 | Scimed Lifesystems Inc. | Polymerization angioplasty balloon implant device |
US5738901A (en) | 1993-09-20 | 1998-04-14 | Scimed Life Systems, Inc. | Catheter balloon with retraction coating |
US5432851A (en) * | 1993-10-21 | 1995-07-11 | Tecsec Incorporated | Personal computer access control system |
IT1269443B (en) * | 1994-01-19 | 1997-04-01 | Stefano Nazari | VASCULAR PROSTHESIS FOR THE REPLACEMENT OR INTERNAL COATING OF MEDIUM AND LARGE DIAMETER BLOOD VESSELS AND DEVICE FOR ITS APPLICATION WITHOUT INTERRUPTION OF BLOOD FLOW |
US5423851A (en) | 1994-03-06 | 1995-06-13 | Samuels; Shaun L. W. | Method and apparatus for affixing an endoluminal device to the walls of tubular structures within the body |
US5556426A (en) | 1994-08-02 | 1996-09-17 | Meadox Medicals, Inc. | PTFE implantable tubular prostheses with external coil support |
US5562727A (en) * | 1994-10-07 | 1996-10-08 | Aeroquip Corporation | Intraluminal graft and method for insertion thereof |
US5534024A (en) * | 1994-11-04 | 1996-07-09 | Aeroquip Corporation | Intraluminal stenting graft |
US5507770A (en) * | 1994-11-23 | 1996-04-16 | Aeroquip Corporation | Intraluminal grafting stent and method for implanting same in a blood vessel |
IT1273855B (en) * | 1994-12-16 | 1997-07-11 | Xtrode Srl | PROSTHESIS FOR VENOUS CAVITY |
NL9500147A (en) * | 1995-01-26 | 1996-09-02 | Industrial Res Bv | A method of manufacturing a sheath-shaped stent from foil material and a stent obtained using this method. |
US5755770A (en) | 1995-01-31 | 1998-05-26 | Boston Scientific Corporatiion | Endovascular aortic graft |
US6053943A (en) * | 1995-12-08 | 2000-04-25 | Impra, Inc. | Endoluminal graft with integral structural support and method for making same |
FR2735476B1 (en) | 1995-06-14 | 1997-07-18 | Rhone Poulenc Rorer Sa | NEW APPLICATION OF PYRROLE DERIVATIVES |
US5676685A (en) * | 1995-06-22 | 1997-10-14 | Razavi; Ali | Temporary stent |
US5725568A (en) | 1995-06-27 | 1998-03-10 | Scimed Life Systems, Inc. | Method and device for recanalizing and grafting arteries |
US5554180A (en) * | 1995-07-07 | 1996-09-10 | Aeroquip Corporation | Intraluminal stenting graft |
US5713948A (en) * | 1995-07-19 | 1998-02-03 | Uflacker; Renan | Adjustable and retrievable graft and graft delivery system for stent-graft system |
US5766203A (en) * | 1995-07-20 | 1998-06-16 | Intelliwire, Inc. | Sheath with expandable distal extremity and balloon catheters and stents for use therewith and method |
US5665117A (en) | 1995-11-27 | 1997-09-09 | Rhodes; Valentine J. | Endovascular prosthesis with improved sealing means for aneurysmal arterial disease and method of use |
US5725547A (en) * | 1996-01-04 | 1998-03-10 | Chuter; Timothy A. M. | Corrugated stent |
CA2420638C (en) | 1996-02-13 | 2008-04-08 | Scimed Life Systems, Inc. | Endovascular apparatus |
US5871537A (en) | 1996-02-13 | 1999-02-16 | Scimed Life Systems, Inc. | Endovascular apparatus |
CA2197375C (en) | 1996-02-15 | 2003-05-06 | Yasuhiro Okuda | Artificial blood vessel |
NL1003178C2 (en) * | 1996-05-21 | 1997-11-25 | Cordis Europ | Tubular prosthesis made of curable material. |
US5716397A (en) * | 1996-12-06 | 1998-02-10 | Medtronic, Inc. | Annuloplasty device with removable stiffening element |
US5947995A (en) | 1997-06-06 | 1999-09-07 | Samuels; Shaun Lawrence Wilkie | Method and apparatus for removing blood clots and other objects |
US6007575A (en) | 1997-06-06 | 1999-12-28 | Samuels; Shaun Laurence Wilkie | Inflatable intraluminal stent and method for affixing same within the human body |
US6015474A (en) * | 1997-06-20 | 2000-01-18 | Protein Polymer Technologies | Methods of using primer molecules for enhancing the mechanical performance of tissue adhesives and sealants |
GB9713624D0 (en) | 1997-06-28 | 1997-09-03 | Anson Medical Ltd | Expandable device |
US5908435A (en) | 1997-10-23 | 1999-06-01 | Samuels; Shaun L. W. | Expandable lumen device and method of use |
US6395019B2 (en) | 1998-02-09 | 2002-05-28 | Trivascular, Inc. | Endovascular graft |
US6015424A (en) | 1998-04-28 | 2000-01-18 | Microvention, Inc. | Apparatus and method for vascular embolization |
US6047825A (en) | 1998-08-21 | 2000-04-11 | Samuels; Shaun Lawrence Wilkie | Method and apparatus for storing medical guidewires |
US20030225453A1 (en) | 1999-03-03 | 2003-12-04 | Trivascular, Inc. | Inflatable intraluminal graft |
US6312462B1 (en) | 1999-09-22 | 2001-11-06 | Impra, Inc. | Prosthesis for abdominal aortic aneurysm repair |
US6355063B1 (en) * | 2000-01-20 | 2002-03-12 | Impra, Inc. | Expanded PTFE drug delivery graft |
US6428566B1 (en) * | 2000-10-31 | 2002-08-06 | Advanced Cardiovascular Systems, Inc. | Flexible hoop and link sheath for a stent delivery system |
US6588588B2 (en) | 2001-04-10 | 2003-07-08 | Shaun L. W. Samuels | Medical guidewire adapter for packaging reuse |
-
1996
- 1996-02-13 US US08/600,834 patent/US5871537A/en not_active Expired - Lifetime
-
1997
- 1997-02-13 WO PCT/US1997/002377 patent/WO1997029716A1/en active Application Filing
- 1997-02-13 EP EP97906917A patent/EP0959810B1/en not_active Expired - Lifetime
- 1997-02-13 CA CA002246355A patent/CA2246355C/en not_active Expired - Fee Related
- 1997-02-13 AT AT97906917T patent/ATE552799T1/en active
-
1998
- 1998-07-06 US US09/111,264 patent/US6059823A/en not_active Expired - Lifetime
-
2000
- 2000-05-08 US US09/566,335 patent/US6319276B1/en not_active Expired - Lifetime
-
2001
- 2001-10-30 US US10/003,218 patent/US6692523B2/en not_active Expired - Lifetime
-
2002
- 2002-11-05 US US10/288,185 patent/US7491230B2/en not_active Expired - Fee Related
-
2003
- 2003-02-18 US US10/369,910 patent/US20030208257A1/en not_active Abandoned
- 2003-06-03 US US10/454,896 patent/US20030220684A1/en not_active Abandoned
-
2004
- 2004-05-11 US US10/842,754 patent/US7255711B2/en not_active Expired - Fee Related
-
2006
- 2006-07-26 US US11/493,306 patent/US7799068B2/en not_active Expired - Fee Related
-
2007
- 2007-08-14 US US11/891,934 patent/US7785365B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20030208257A1 (en) | 2003-11-06 |
WO1997029716A1 (en) | 1997-08-21 |
US20070282424A1 (en) | 2007-12-06 |
EP0959810B1 (en) | 2012-04-11 |
US5871537A (en) | 1999-02-16 |
US20040215321A1 (en) | 2004-10-28 |
EP0959810A1 (en) | 1999-12-01 |
US7255711B2 (en) | 2007-08-14 |
US20060276881A1 (en) | 2006-12-07 |
CA2246355A1 (en) | 1997-08-21 |
US20030220684A1 (en) | 2003-11-27 |
US6059823A (en) | 2000-05-09 |
US6692523B2 (en) | 2004-02-17 |
US20020040235A1 (en) | 2002-04-04 |
US7491230B2 (en) | 2009-02-17 |
ATE552799T1 (en) | 2012-04-15 |
US20030083738A1 (en) | 2003-05-01 |
US6319276B1 (en) | 2001-11-20 |
US7785365B2 (en) | 2010-08-31 |
US7799068B2 (en) | 2010-09-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2246355C (en) | Endovascular apparatus | |
US20210093473A1 (en) | System and methods for endovascular aneurysm treatment | |
AU687304B2 (en) | Expandable transluminal graft prosthesis for repair of aneurysm and method for implanting | |
US6878161B2 (en) | Stent graft loading and deployment device and method | |
AU669338B2 (en) | Expandable transluminal graft prosthesis for repair of aneurysm and method for implanting | |
US6322587B1 (en) | Bifurcated multicapsule intraluminal grafting system and method | |
EP0183372A1 (en) | Prosthetic stent | |
JP2015057243A (en) | Devices and methods for treatment of abdominal aortic aneurysms | |
JP2015516844A (en) | Kink resistant stent graft | |
AU739203B2 (en) | A device for grafting a prosthesis |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20160215 |