CA2239070A1 - Systems and methods for removing viral agents from blood - Google Patents
Systems and methods for removing viral agents from bloodInfo
- Publication number
- CA2239070A1 CA2239070A1 CA002239070A CA2239070A CA2239070A1 CA 2239070 A1 CA2239070 A1 CA 2239070A1 CA 002239070 A CA002239070 A CA 002239070A CA 2239070 A CA2239070 A CA 2239070A CA 2239070 A1 CA2239070 A1 CA 2239070A1
- Authority
- CA
- Canada
- Prior art keywords
- methods
- systems
- plasma
- cellular matter
- blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title abstract 5
- 239000008280 blood Substances 0.000 title 1
- 210000004369 blood Anatomy 0.000 title 1
- 230000003612 virological effect Effects 0.000 title 1
- 230000001413 cellular effect Effects 0.000 abstract 4
- 239000000356 contaminant Substances 0.000 abstract 4
- 239000000463 material Substances 0.000 abstract 2
- 238000001914 filtration Methods 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/022—Filtration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/08—Radiation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
- C12N7/06—Inactivation or attenuation by chemical treatment
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Developmental Biology & Embryology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- External Artificial Organs (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
Systems and methods treat plasma carrying contaminants and cellular matter that are capable of entraining contaminants. The systems and methods separate cellular matter from the plasma by filtration, thereby removing contaminants entrained within the cellular matter. The system and methods add to the plasma a photoactive material. The systems and methods emit radiation at a selected wavelength into the plasma to activate the photoactive material and thereby eradicate the contaminant that is free of entrainment by cellular matter.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/742,572 US6190855B1 (en) | 1996-10-28 | 1996-10-28 | Systems and methods for removing viral agents from blood |
US08/742,572 | 1996-10-28 | ||
PCT/US1997/017984 WO1998018908A1 (en) | 1996-10-28 | 1997-10-03 | Systems and methods for removing viral agents from blood |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2239070A1 true CA2239070A1 (en) | 1998-05-07 |
CA2239070C CA2239070C (en) | 2005-06-21 |
Family
ID=24985365
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002239070A Expired - Lifetime CA2239070C (en) | 1996-10-28 | 1997-10-03 | Systems and methods for removing viral agents from blood |
Country Status (11)
Country | Link |
---|---|
US (3) | US6190855B1 (en) |
EP (1) | EP0870013B1 (en) |
JP (1) | JP2000507485A (en) |
KR (1) | KR100490072B1 (en) |
CN (1) | CN1160453C (en) |
AU (1) | AU735878B2 (en) |
CA (1) | CA2239070C (en) |
DE (1) | DE69739503D1 (en) |
NO (1) | NO982981L (en) |
TW (1) | TW346398B (en) |
WO (1) | WO1998018908A1 (en) |
Families Citing this family (70)
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US5935092A (en) * | 1990-12-20 | 1999-08-10 | Baxter International Inc. | Systems and methods for removing free and entrained contaminants in plasma |
US20040067157A1 (en) * | 1993-07-22 | 2004-04-08 | Clearant, Inc. | Methods for sterilizing biological materials |
US5362442A (en) * | 1993-07-22 | 1994-11-08 | 2920913 Canada Inc. | Method for sterilizing products with gamma radiation |
US6168718B1 (en) | 1996-11-08 | 2001-01-02 | Pall Corporation | Method for purifying blood plasma and apparatus suitable therefor |
US6197207B1 (en) * | 1997-05-21 | 2001-03-06 | Baxter International Inc. | Method of reducing the possibility of transmission of spongiform encephalopathy diseases by blood products |
US20030194433A1 (en) * | 2002-03-12 | 2003-10-16 | Ecolab | Antimicrobial compositions, methods and articles employing singlet oxygen- generating agent |
US20040055965A1 (en) * | 1997-06-13 | 2004-03-25 | Hubig Stephan M. | Recreational water treatment employing singlet oxygen |
US6669905B1 (en) * | 1998-05-21 | 2003-12-30 | Baxter International Inc. | Systems and methods for collecting plasma that is free or virtually free of cellular blood species |
US6267745B1 (en) | 1998-05-21 | 2001-07-31 | Baxter International Inc. | Confined air tube and methods for handling air in closed blood processing systems |
FR2782730B1 (en) * | 1998-08-25 | 2002-05-17 | Biocom Sa | CELL SEPARATION PROCESS FOR THE ISOLATION OF PATHOGENIC CELLS, PARTICULARLY RARE CANCERES, EQUIPMENT AND REAGENT FOR IMPLEMENTING THE PROCESS AND APPLICATION OF THE PROCESS |
US7025877B1 (en) * | 1999-06-03 | 2006-04-11 | Baxter International Inc. | Processing set for processing and treating a biological fluid |
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FR2799986B1 (en) * | 1999-10-20 | 2001-11-23 | Maco Pharma Sa | FILTER UNIT OF A VIRUCID SUBSTANCE |
US7331350B2 (en) * | 2000-02-11 | 2008-02-19 | The General Hospital Corporation | Photochemical tissue bonding |
US20040086420A1 (en) * | 2000-03-23 | 2004-05-06 | Macphee Martin J. | Methods for sterilizing serum or plasma |
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US7252799B2 (en) * | 2001-08-31 | 2007-08-07 | Clearant, Inc. | Methods for sterilizing preparations containing albumin |
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US20110091353A1 (en) * | 2001-09-24 | 2011-04-21 | Wilson Burgess | Methods for Sterilizing Tissue |
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US20030185702A1 (en) * | 2002-02-01 | 2003-10-02 | Wilson Burgess | Methods for sterilizing tissue |
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US20030124023A1 (en) * | 2001-12-21 | 2003-07-03 | Wilson Burgess | Method of sterilizing heart valves |
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US20070020300A1 (en) * | 2002-03-12 | 2007-01-25 | Ecolab Inc. | Recreational water treatment employing singlet oxygen |
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US8631683B2 (en) | 2007-02-06 | 2014-01-21 | Fresenius Medical Care Holdings, Inc. | Dialysis systems including non-invasive multi-function sensor systems |
US8889004B2 (en) | 2007-11-16 | 2014-11-18 | Fresenius Medical Care Holdings, Inc. | Dialysis systems and methods |
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US8449686B2 (en) | 2010-04-26 | 2013-05-28 | Fresenius Medical Care Holdings, Inc. | Methods for cleaning a drain line of a dialysis machine |
US8784668B2 (en) | 2010-10-12 | 2014-07-22 | Fresenius Medical Care Holdings, Inc. | Systems and methods for compensation of compliant behavior in regenerative dialysis systems |
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US6319662B1 (en) * | 1993-12-17 | 2001-11-20 | Baxter International Inc. | Method and apparatus for removing viral contaminants from a body fluid |
US5639376A (en) | 1994-01-10 | 1997-06-17 | Hemasure, Inc. | Process for simultaneously removing leukocytes and methylene blue from plasma |
ITMI940055A1 (en) | 1994-01-18 | 1995-07-18 | Bracco Spa | CONTAINER FOR DIAGNOSTIC COUNTERTOGRAPHIC SOLUTIONS |
US5545339A (en) | 1994-02-25 | 1996-08-13 | Pall Corporation | Method for processing biological fluid and treating separated component |
US5660731A (en) | 1994-11-08 | 1997-08-26 | Pall Corporation | Filter for separating photoactive agent |
JP3541245B2 (en) * | 1997-07-15 | 2004-07-07 | 株式会社日立グローバルストレージテクノロジーズ | Magnetic head and magnetic storage device having the same |
-
1996
- 1996-10-28 US US08/742,572 patent/US6190855B1/en not_active Expired - Lifetime
-
1997
- 1997-10-03 WO PCT/US1997/017984 patent/WO1998018908A1/en active IP Right Grant
- 1997-10-03 CA CA002239070A patent/CA2239070C/en not_active Expired - Lifetime
- 1997-10-03 KR KR1019980705000A patent/KR100490072B1/en not_active IP Right Cessation
- 1997-10-03 EP EP97911624A patent/EP0870013B1/en not_active Expired - Lifetime
- 1997-10-03 DE DE69739503T patent/DE69739503D1/en not_active Expired - Lifetime
- 1997-10-03 AU AU48948/97A patent/AU735878B2/en not_active Expired
- 1997-10-03 CN CNB971923620A patent/CN1160453C/en not_active Expired - Lifetime
- 1997-10-03 JP JP10520488A patent/JP2000507485A/en active Pending
- 1997-10-14 TW TW086115002A patent/TW346398B/en active
-
1998
- 1998-06-26 NO NO982981A patent/NO982981L/en not_active Application Discontinuation
-
2000
- 2000-10-13 US US09/688,079 patent/US6855489B1/en not_active Expired - Lifetime
-
2005
- 2005-02-11 US US11/056,347 patent/US7374870B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
TW346398B (en) | 1998-12-01 |
CA2239070C (en) | 2005-06-21 |
US7374870B2 (en) | 2008-05-20 |
US20050186553A1 (en) | 2005-08-25 |
NO982981D0 (en) | 1998-06-26 |
KR100490072B1 (en) | 2006-03-23 |
US6855489B1 (en) | 2005-02-15 |
US6190855B1 (en) | 2001-02-20 |
AU735878B2 (en) | 2001-07-19 |
JP2000507485A (en) | 2000-06-20 |
WO1998018908A1 (en) | 1998-05-07 |
NO982981L (en) | 1998-06-26 |
DE69739503D1 (en) | 2009-09-03 |
KR19990076873A (en) | 1999-10-25 |
EP0870013A4 (en) | 2003-02-05 |
CN1211277A (en) | 1999-03-17 |
AU4894897A (en) | 1998-05-22 |
EP0870013A1 (en) | 1998-10-14 |
EP0870013B1 (en) | 2009-07-22 |
CN1160453C (en) | 2004-08-04 |
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