CA2235783C - A stent - Google Patents

A stent Download PDF

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Publication number
CA2235783C
CA2235783C CA002235783A CA2235783A CA2235783C CA 2235783 C CA2235783 C CA 2235783C CA 002235783 A CA002235783 A CA 002235783A CA 2235783 A CA2235783 A CA 2235783A CA 2235783 C CA2235783 C CA 2235783C
Authority
CA
Canada
Prior art keywords
stent
stress
lumen
loading
alloy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002235783A
Other languages
French (fr)
Other versions
CA2235783A1 (en
Inventor
Thomas Duerig
Dieter Stockel
Janet Burpee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nitinol Development Corp
Original Assignee
Nitinol Development Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nitinol Development Corp filed Critical Nitinol Development Corp
Priority to CA2589000A priority Critical patent/CA2589000C/en
Publication of CA2235783A1 publication Critical patent/CA2235783A1/en
Application granted granted Critical
Publication of CA2235783C publication Critical patent/CA2235783C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • A61L31/022—Metals or alloys
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22F—CHANGING THE PHYSICAL STRUCTURE OF NON-FERROUS METALS AND NON-FERROUS ALLOYS
    • C22F1/00—Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working
    • C22F1/006—Resulting in heat recoverable alloys with a memory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/16—Materials with shape-memory or superelastic properties

Abstract

A stent for use in a lumen in a human or animal body, has a generally tubular body formed from a shape memory alloy which has been treated so that it exhibits enhanced elastic properties with a point of inflection in the stress-strain curve on loading, enabling the body to be deformed inwardly to a transversely compressed configuration for insertion into the lumen and then revert towards its initial configuration, into contact with and to support the lumen. The shape memory alloy comprises nickel, titanium and from about 3 at.% to about 20 at.%, based on the weight of the total weight of the alloy composition, of a ternary element selected from the group consisting of niobium, hafnium, tantalum, tungsten and gold. The ratio of the stress on loading to the stress on unloading at the respective inflection points on the loading and unloading curves is at least about 2.5:1, and the difference between the stresses on loading and unloading at the inflection points at least about 250 MPa.

Claims (11)

1. A stent for use in a lumen in a human or animal, which has a generally tubular body formed from a superelastic shape memory alloy having an Af temperature at least about 10. degree. C. which has been treated so that it exhibits enhanced elastic properties with a point of inflection in the stress-strain curve on loading, enabling the body to be deformed inwardly to a transversely compressed configuration for insertion into the lumen and then revert towards its initial configuration, into contact with and to support the lumen, the shape memory alloy comprising nickel, titanium and from about 3 wt. % to about 20 wt. %, based on the weight of the total weight of the alloy composition, of at least one additional element selected from the group consisting of niobium, hafnium, tantalum, tungsten and gold, the ratio of the stress on loading to the stress on unloading at the respective inflection points on the stress-strain curve being at least about 2.5:1.
2. A stent as claimed in claim 1, in which the alloy comprises at least about 5 wt. t of the ternary element.
3. A stent as claimed in claim 1, in which the alloy comprises not more than about 10 wt. % of the ternary element.
4. A stent as claimed in claim 1, in which the Af temperature of the alloy is at least about 15° C.
5. A stent as claimed in claim 1, in which the Af temperature of the alloy is not more than about 40° C.
6. A stent as claimed in claim 1, which comprises a plurality of wire segments extending at least partially around the circumference of the stent.
7. A stent as claimed in claim 6, which includes generally longitudinally extending portions linking the circumferential wire segments.
8. A stent as claimed in claim 1, which is located within a restraint by which it is held in a configuration in which it has been transversely compressed elastically.
9. A stent for use in a lumen in a human or animal body, which has a generally tubular body formed from a superelastic shape memory alloy having an Af temperature less than about 15° C. which has been treated so that it exhibits enhanced elastic properties with a point of inflection in the stress-strain curve on loading, enabling the body to be deformed inwardly to a transversely compressed configuration for insertion into the lumen and then revert towards its initial configuration, into contact with and to support the lumen, the ratio of the stress on loading to the stress on unloading at the respective inflection points on the stress-strain curve being at least about 2.5:1.
10. A stent as claimed in claim 9, in which the value of the said ratio is at least about 3:1.
11. A stent as claimed in claim 9, in which the shape memory alloy comprises nickel, titanium and from about 3 wt. % to about 20 wt. %, based on the weight of the total weight of the alloy composition, of a ternary element selected from the group consisting of niobium, hafnium, tantalum, tungsten and gold.
CA002235783A 1997-04-25 1998-04-24 A stent Expired - Lifetime CA2235783C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2589000A CA2589000C (en) 1997-04-25 1998-04-24 A stent

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/846,130 US6312455B2 (en) 1997-04-25 1997-04-25 Stent
US08/846,130 1997-04-25

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2589000A Division CA2589000C (en) 1997-04-25 1998-04-24 A stent

Publications (2)

Publication Number Publication Date
CA2235783A1 CA2235783A1 (en) 1998-10-25
CA2235783C true CA2235783C (en) 2008-11-04

Family

ID=25297032

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002235783A Expired - Lifetime CA2235783C (en) 1997-04-25 1998-04-24 A stent

Country Status (5)

Country Link
US (1) US6312455B2 (en)
EP (1) EP0873734B1 (en)
JP (1) JP4248618B2 (en)
CA (1) CA2235783C (en)
DE (1) DE69819063T2 (en)

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Also Published As

Publication number Publication date
JPH1142283A (en) 1999-02-16
US20010007953A1 (en) 2001-07-12
DE69819063D1 (en) 2003-11-27
US6312455B2 (en) 2001-11-06
EP0873734A2 (en) 1998-10-28
EP0873734A3 (en) 1999-09-01
DE69819063T2 (en) 2004-07-08
CA2235783A1 (en) 1998-10-25
JP4248618B2 (en) 2009-04-02
EP0873734B1 (en) 2003-10-22

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