CA2235738A1 - Detection of biological molecules using chemical amplification and optical sensors - Google Patents

Detection of biological molecules using chemical amplification and optical sensors

Info

Publication number
CA2235738A1
CA2235738A1 CA002235738A CA2235738A CA2235738A1 CA 2235738 A1 CA2235738 A1 CA 2235738A1 CA 002235738 A CA002235738 A CA 002235738A CA 2235738 A CA2235738 A CA 2235738A CA 2235738 A1 CA2235738 A1 CA 2235738A1
Authority
CA
Canada
Prior art keywords
detection
optical sensors
biological molecules
chemical amplification
analyte
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002235738A
Other languages
French (fr)
Other versions
CA2235738C (en
Inventor
William Peter Van Antwerp
John Joseph Mastrototaro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medtronic Minimed Inc
Original Assignee
Minimed, Inc.
William Peter Van Antwerp
John Joseph Mastrototaro
Medtronic Minimed, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21726654&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2235738(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Minimed, Inc., William Peter Van Antwerp, John Joseph Mastrototaro, Medtronic Minimed, Inc. filed Critical Minimed, Inc.
Publication of CA2235738A1 publication Critical patent/CA2235738A1/en
Application granted granted Critical
Publication of CA2235738C publication Critical patent/CA2235738C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes

Abstract

Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an analyte transducer immobilized in a polymeric matrix, where the system is implantable and biocompatible. Upon interrogation by an optical system, the amplification system produces a signal capable of detection external to the skin of the patient. Quantitation of the analyte of interest is achieved by measurement of the emitted signal.
CA002235738A 1995-11-22 1996-11-21 Detection of biological molecules using chemical amplification and optical sensors Expired - Fee Related CA2235738C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US751595P 1995-11-22 1995-11-22
US60/007,515 1995-11-22
PCT/US1996/018720 WO1997019188A1 (en) 1995-11-22 1996-11-21 Detection of biological molecules using chemical amplification and optical sensors

Publications (2)

Publication Number Publication Date
CA2235738A1 true CA2235738A1 (en) 1997-05-29
CA2235738C CA2235738C (en) 2005-07-26

Family

ID=21726654

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002235738A Expired - Fee Related CA2235738C (en) 1995-11-22 1996-11-21 Detection of biological molecules using chemical amplification and optical sensors

Country Status (8)

Country Link
US (3) US6011984A (en)
EP (1) EP0862648B1 (en)
JP (1) JP2000500656A (en)
AT (1) ATE278801T1 (en)
AU (1) AU1058297A (en)
CA (1) CA2235738C (en)
DE (1) DE69633573T2 (en)
WO (1) WO1997019188A1 (en)

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