CA2233108A1 - Complex of y-cyclodextrin and retinol or retinol derivatives, processes for their preparation and their use - Google Patents
Complex of y-cyclodextrin and retinol or retinol derivatives, processes for their preparation and their useInfo
- Publication number
- CA2233108A1 CA2233108A1 CA002233108A CA2233108A CA2233108A1 CA 2233108 A1 CA2233108 A1 CA 2233108A1 CA 002233108 A CA002233108 A CA 002233108A CA 2233108 A CA2233108 A CA 2233108A CA 2233108 A1 CA2233108 A1 CA 2233108A1
- Authority
- CA
- Canada
- Prior art keywords
- retinol
- cyclodextrin
- processes
- preparation
- complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0212—Face masks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/738—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/12—Face or body powders for grooming, adorning or absorbing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Abstract
Complexes of .gamma.-cyclodextrin and retinol or retinol derivatives, along with processes for their preparation and compositions for their use. The complexes are useful in cosmetic formulations and in pharmaceutical formulations.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19713092.5 | 1997-03-27 | ||
DE19713092A DE19713092A1 (en) | 1997-03-27 | 1997-03-27 | Complexes of gamma-cyclodextrin and retinol or retinol derivatives, as well as processes for their preparation and their use |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2233108A1 true CA2233108A1 (en) | 1998-09-27 |
CA2233108C CA2233108C (en) | 2005-07-26 |
Family
ID=7824924
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002233108A Expired - Fee Related CA2233108C (en) | 1997-03-27 | 1998-03-20 | Complex of y-cyclodextrin and retinol or retinol derivatives, processes for their preparation and their use |
Country Status (7)
Country | Link |
---|---|
US (1) | US5985296A (en) |
EP (1) | EP0867175B1 (en) |
JP (1) | JP3010435B2 (en) |
KR (1) | KR100304382B1 (en) |
CA (1) | CA2233108C (en) |
DE (2) | DE19713092A1 (en) |
HU (1) | HUP9800688A3 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113244157A (en) * | 2021-06-04 | 2021-08-13 | 何平蓉 | Anti-darkness makeup powder cake and preparation method thereof |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100560188B1 (en) * | 1997-11-27 | 2006-03-13 | 가부시키가이샤 시세이도 | Face pack |
DE19847633C1 (en) * | 1998-10-15 | 2000-03-02 | Wacker Chemie Gmbh | Preparation of retinol-gamma cyclodextrin complex useful in skin care cosmetic or dermatological compositions comprises using retinol as solution in polysorbate, giving quantitative conversion to stable complex |
DE19943678A1 (en) * | 1999-09-13 | 2001-03-15 | Beiersdorf Ag | Active substance combinations of surface-active citric acid esters and inclusion compounds of cyclodextrins and retinoids and cosmetic and dermatological preparations containing such mixtures |
CA2414406A1 (en) * | 2000-06-26 | 2002-01-03 | The Regents Of The University Of Michigan | Use of egf-r protein tyrosine kinase inhibitors for preventing photoaging in human skin |
KR100402576B1 (en) * | 2000-07-05 | 2003-10-22 | 동아제약 주식회사 | Cosmetic composition containing retinol by multiple stabilization |
IT1317911B1 (en) * | 2000-09-28 | 2003-07-15 | Idi Irccs | COSMETIC FORMULATION. |
KR100437102B1 (en) * | 2001-01-11 | 2004-06-23 | (주)케비젠 | New retinol derivatives, the method of preparations and the uses thereof |
BR0207663A (en) * | 2001-02-27 | 2005-10-25 | Univ Michigan | Use of natural egfr inhibitors to prevent side effects due to therapy with retinoids, soaps and other stimuli that activate the epidermal growth factor receptor. |
DE10141682A1 (en) * | 2001-08-25 | 2003-03-06 | Beiersdorf Ag | Cyclodextrin is used in production of cosmetic and dermatological compositions to give improved filler distribution on the skin |
DE10151245A1 (en) * | 2001-10-17 | 2003-05-15 | Beiersdorf Ag | Cosmetic and / or dermatological combination of active ingredients |
EP1304161B1 (en) * | 2001-10-19 | 2007-02-28 | Pacific Corporation | Thermotropic liquid crystal polymer microcapsules, a method for preparing the same, and cosmetic compositions containing the same |
JP4528903B2 (en) * | 2002-03-11 | 2010-08-25 | 石川県 | Method for producing cyclodextrin inclusion product of plant-containing active ingredient |
DE10224298A1 (en) * | 2002-05-31 | 2003-12-18 | Beiersdorf Ag | Combinations of cyclodextrins, retinoids and/or bioquinones and selected polymers useful in cosmetic or dermatological compositions |
US20030232091A1 (en) * | 2002-06-17 | 2003-12-18 | Adi Shefer | Stabilized retinol for cosmetic dermatological, and pharmaceutical compositions, and use thereof |
FI20030426A (en) * | 2003-03-24 | 2004-09-25 | Tomi Jaervinen | cyclodextrin complexes |
US20060177405A1 (en) * | 2005-02-04 | 2006-08-10 | Morrissey Maureen S | Moisturizing compositions |
CN101223183A (en) * | 2005-06-13 | 2008-07-16 | 嘉吉公司 | Cyclodextrin inclusion complexes and methods of preparing same |
WO2006137958A1 (en) * | 2005-06-13 | 2006-12-28 | Cargill Incorporated | Cyclodextrin inclusion complexes and methods of preparing same |
CN101431980B (en) * | 2006-05-02 | 2012-08-01 | 株式会社东洋发酵 | Fermented product composition, cosmetic composition and method of producing the same |
EP2027136A4 (en) * | 2006-06-13 | 2011-08-03 | Cargill Inc | Large-particle cyclodextrin inclusion complexes and methods of preparing same |
JP5253171B2 (en) * | 2006-09-22 | 2013-07-31 | 株式会社クラベ | PTFE porous body, PTFE mixture, method for producing PTFE porous body, and electric wire / cable using PTFE porous body |
JP2010514794A (en) * | 2006-12-27 | 2010-05-06 | カーギル インコーポレイテッド | Cyclodextrin-encapsulated complex and method for preparing the complex |
US20080283693A1 (en) * | 2007-05-15 | 2008-11-20 | Evans Michael J F | Propulsion apparatus and system |
DE102007051614A1 (en) * | 2007-10-24 | 2009-04-30 | Coty Prestige Lancaster Group Gmbh | Retinol-containing cosmetic product |
DE102008022041A1 (en) * | 2008-04-29 | 2009-11-05 | Coty Prestige Lancaster Group Gmbh | Cosmetic product with delayed retinol release |
US8410079B2 (en) | 2010-08-06 | 2013-04-02 | Island Kinetics | Chirally correct retinal cyclodextrin hemiacetals for clarifying skin complexion |
US20130251644A1 (en) * | 2012-03-22 | 2013-09-26 | Precision Dermatology, Inc. | Cyclodextrin-Based Microemulsions, and Dermatological Uses Thereof |
WO2014055532A2 (en) * | 2012-10-02 | 2014-04-10 | Allergan, Inc. | Dermal filler hydrogels with vitamin a/cyclodextrin inclusion complexes |
CN105611909B (en) | 2013-03-12 | 2020-09-15 | 普莱玛疗法公司 | Dental compositions comprising chelating agents and bases |
KR101503301B1 (en) * | 2013-07-22 | 2015-03-17 | 주식회사 웰코스 | Retinylpalmitate stabilized formulations |
EP3290026A1 (en) | 2016-09-06 | 2018-03-07 | Athenion AG | Method for solubilizing poorly water-soluble dietary supplements and pharmaceutically active agents |
EP3421096A1 (en) | 2017-06-30 | 2019-01-02 | Athenion AG | Method for solubilizing poorly water-soluble cosmetic agents |
WO2019150087A1 (en) * | 2018-01-30 | 2019-08-08 | Olusola Clement Idowu | Mangiferin as a protective agent against mitochondrial dna damage and skin-care compositions comprising same |
CN112294693B (en) * | 2019-07-26 | 2021-07-20 | 珀莱雅化妆品股份有限公司 | Supermolecule preparation of retinol and derivatives thereof and preparation method thereof |
CN110623859A (en) * | 2019-10-25 | 2019-12-31 | 广州市博之越精细化工有限公司 | Preparation method of hydroxypropyl cyclodextrin inclusion retinol |
KR102297632B1 (en) * | 2021-04-19 | 2021-09-06 | 주식회사 라파스 | Composition for manufacturing microneedle including cyclodextrin for stablilzing retinol, and microneedle manufactured with the same composition |
CN113181078A (en) * | 2021-05-21 | 2021-07-30 | 何平蓉 | Moistening and astringing type deep cleaning mask powder |
CN113318027A (en) * | 2021-06-15 | 2021-08-31 | 何平蓉 | Mild oil-control acne-removing facial cleansing composition and preparation method thereof |
CN114869797B (en) * | 2022-03-22 | 2023-07-21 | 深圳市美莲达生物科技有限公司 | Essence containing retinol and rhizoma polygonati polysaccharide and application thereof |
CN114652659B (en) * | 2022-05-10 | 2023-07-14 | 广州兰蝶生物科技有限公司 | Moisturizing gel containing aloe and rose hydrosol |
CN115381732B (en) * | 2022-08-01 | 2023-05-12 | 广州市博之越精细化工有限公司 | Preparation method of hydroxypropyl cyclodextrin inclusion retinol |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2827452A (en) * | 1955-05-31 | 1958-03-18 | Univ Minnesota | Stabilization of materials |
US4371673A (en) * | 1980-07-21 | 1983-02-01 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Water soluble forms of retinoids |
US5002935A (en) * | 1987-12-30 | 1991-03-26 | University Of Florida | Improvements in redox systems for brain-targeted drug delivery |
ES2058503T5 (en) * | 1988-03-29 | 1999-04-16 | Univ Florida | PHARMACEUTICAL FORMULATIONS FOR PARENTERAL USE. |
JP2779424B2 (en) * | 1988-10-19 | 1998-07-23 | 日清製粉株式会社 | α-Tocopherol vitamin A acid ester-cyclodextrin complex |
FR2647015B1 (en) * | 1989-05-17 | 1994-05-06 | Cird | AQUEOUS GEL BASED ON RETINOIC ACID AND ITS USE IN HUMAN MEDICINE AND COSMETICS |
ES2062359T3 (en) * | 1989-05-24 | 1994-12-16 | Innovet Inc | A PROCEDURE FOR THE PREPARATION OF AN ANESTHETIC OR HYPOALLERGENIC STEROID HYPNOTIC COMPOSITION. |
KR0166088B1 (en) * | 1990-01-23 | 1999-01-15 | . | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
CA2013485C (en) * | 1990-03-06 | 1997-04-22 | John Michael Gardlik | Solid consumer product compositions containing small particle cyclodextrin complexes |
EP1714640A1 (en) * | 1992-07-13 | 2006-10-25 | Shiseido Company, Ltd. | Stabilised external skin treatment composition comprising retinol. |
US5472954A (en) * | 1992-07-14 | 1995-12-05 | Cyclops H.F. | Cyclodextrin complexation |
US5324718A (en) * | 1992-07-14 | 1994-06-28 | Thorsteinn Loftsson | Cyclodextrin/drug complexation |
SE9300971D0 (en) * | 1993-03-24 | 1993-03-24 | Jan Wadstein | HUDVAARDSKOMPOSITION |
ATE196427T1 (en) * | 1993-12-06 | 2000-10-15 | Takeda Chemical Industries Ltd | COMPOSITION WITH IMPROVED WATER SOLUBILITY, CONTAINING A WATER-INSOLUBLE OR POORLY WATER-INSOLUBLE COMPOUND |
-
1997
- 1997-03-27 DE DE19713092A patent/DE19713092A1/en not_active Withdrawn
-
1998
- 1998-02-20 JP JP10039203A patent/JP3010435B2/en not_active Expired - Fee Related
- 1998-03-11 KR KR1019980008105A patent/KR100304382B1/en not_active IP Right Cessation
- 1998-03-19 DE DE59800221T patent/DE59800221D1/en not_active Expired - Lifetime
- 1998-03-19 EP EP98104984A patent/EP0867175B1/en not_active Expired - Lifetime
- 1998-03-20 US US09/045,342 patent/US5985296A/en not_active Expired - Lifetime
- 1998-03-20 CA CA002233108A patent/CA2233108C/en not_active Expired - Fee Related
- 1998-03-27 HU HU9800688A patent/HUP9800688A3/en unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113244157A (en) * | 2021-06-04 | 2021-08-13 | 何平蓉 | Anti-darkness makeup powder cake and preparation method thereof |
Also Published As
Publication number | Publication date |
---|---|
US5985296A (en) | 1999-11-16 |
HUP9800688A3 (en) | 1999-04-28 |
JP3010435B2 (en) | 2000-02-21 |
HUP9800688A2 (en) | 1999-02-01 |
KR19980080135A (en) | 1998-11-25 |
EP0867175B1 (en) | 2000-08-09 |
EP0867175A1 (en) | 1998-09-30 |
DE19713092A1 (en) | 1998-10-01 |
JPH10279504A (en) | 1998-10-20 |
KR100304382B1 (en) | 2002-04-24 |
DE59800221D1 (en) | 2000-09-14 |
CA2233108C (en) | 2005-07-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20150320 |
|
MKLA | Lapsed |
Effective date: 20150320 |