CA2231195A1 - Sustained release matrix for high-dose insoluble drugs - Google Patents
Sustained release matrix for high-dose insoluble drugsInfo
- Publication number
- CA2231195A1 CA2231195A1 CA002231195A CA2231195A CA2231195A1 CA 2231195 A1 CA2231195 A1 CA 2231195A1 CA 002231195 A CA002231195 A CA 002231195A CA 2231195 A CA2231195 A CA 2231195A CA 2231195 A1 CA2231195 A1 CA 2231195A1
- Authority
- CA
- Canada
- Prior art keywords
- sustained release
- insoluble drugs
- release matrix
- dose
- dose insoluble
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Abstract
Sustained release dosage forms of high dose insoluble drugs such as ibuprofen and methods for their manufacture are disclosed.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2133596P | 1996-07-08 | 1996-07-08 | |
US60/021,335 | 1996-07-08 | ||
PCT/US1997/013331 WO1998001117A1 (en) | 1996-07-08 | 1997-07-08 | Sustained release matrix for high-dose insoluble drugs |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2231195A1 true CA2231195A1 (en) | 1998-01-15 |
CA2231195C CA2231195C (en) | 2003-01-21 |
Family
ID=21803631
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002231195A Expired - Fee Related CA2231195C (en) | 1996-07-08 | 1997-07-08 | Sustained release matrix for high-dose insoluble drugs |
Country Status (12)
Country | Link |
---|---|
US (4) | US6093420A (en) |
EP (1) | EP0859603B1 (en) |
JP (1) | JP3148256B2 (en) |
KR (1) | KR100321489B1 (en) |
AT (1) | ATE417604T1 (en) |
AU (1) | AU695734B2 (en) |
CA (1) | CA2231195C (en) |
DE (1) | DE69739165D1 (en) |
ES (1) | ES2322405T3 (en) |
IL (1) | IL123505A (en) |
MX (1) | MX9801835A (en) |
WO (1) | WO1998001117A1 (en) |
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-
1997
- 1997-07-08 MX MX9801835A patent/MX9801835A/en unknown
- 1997-07-08 CA CA002231195A patent/CA2231195C/en not_active Expired - Fee Related
- 1997-07-08 JP JP50540898A patent/JP3148256B2/en not_active Expired - Fee Related
- 1997-07-08 AU AU38183/97A patent/AU695734B2/en not_active Ceased
- 1997-07-08 ES ES97935184T patent/ES2322405T3/en not_active Expired - Lifetime
- 1997-07-08 KR KR1019980701734A patent/KR100321489B1/en not_active IP Right Cessation
- 1997-07-08 DE DE69739165T patent/DE69739165D1/en not_active Expired - Lifetime
- 1997-07-08 AT AT97935184T patent/ATE417604T1/en not_active IP Right Cessation
- 1997-07-08 WO PCT/US1997/013331 patent/WO1998001117A1/en active IP Right Grant
- 1997-07-08 US US08/889,424 patent/US6093420A/en not_active Expired - Lifetime
- 1997-07-08 IL IL12350597A patent/IL123505A/en not_active IP Right Cessation
- 1997-07-08 EP EP97935184A patent/EP0859603B1/en not_active Expired - Lifetime
-
1999
- 1999-10-19 US US09/420,247 patent/US6245355B1/en not_active Expired - Lifetime
-
2001
- 2001-04-25 US US09/842,289 patent/US6689386B2/en not_active Expired - Fee Related
-
2003
- 2003-12-09 US US10/731,859 patent/US20040121012A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1998001117A1 (en) | 1998-01-15 |
JP3148256B2 (en) | 2001-03-19 |
AU3818397A (en) | 1998-02-02 |
MX9801835A (en) | 1998-08-30 |
US20010021392A1 (en) | 2001-09-13 |
AU695734B2 (en) | 1998-08-20 |
US6093420A (en) | 2000-07-25 |
JPH10511407A (en) | 1998-11-04 |
EP0859603B1 (en) | 2008-12-17 |
CA2231195C (en) | 2003-01-21 |
KR19990044486A (en) | 1999-06-25 |
EP0859603A4 (en) | 2006-05-24 |
ATE417604T1 (en) | 2009-01-15 |
IL123505A0 (en) | 1998-10-30 |
IL123505A (en) | 2004-12-15 |
KR100321489B1 (en) | 2002-10-09 |
ES2322405T3 (en) | 2009-06-19 |
DE69739165D1 (en) | 2009-01-29 |
US20040121012A1 (en) | 2004-06-24 |
US6245355B1 (en) | 2001-06-12 |
EP0859603A1 (en) | 1998-08-26 |
US6689386B2 (en) | 2004-02-10 |
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