CA2222706A1 - Radiation treatment of the vascular system - Google Patents

Radiation treatment of the vascular system

Info

Publication number
CA2222706A1
CA2222706A1 CA002222706A CA2222706A CA2222706A1 CA 2222706 A1 CA2222706 A1 CA 2222706A1 CA 002222706 A CA002222706 A CA 002222706A CA 2222706 A CA2222706 A CA 2222706A CA 2222706 A1 CA2222706 A1 CA 2222706A1
Authority
CA
Canada
Prior art keywords
lumen
vascular system
radiation treatment
angioplasty
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002222706A
Other languages
French (fr)
Other versions
CA2222706C (en
Inventor
Ron Waksman
Thomas D. Weldon
Raphael F. Meloul
Richard A. Hillstead
Jonathan J. Rosen
George K. Bonnoitt
David S. Halpern
Charles E. Larsen
Ian R. Crocker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Emory University
Best Vascular Inc
Original Assignee
Novoste Corporation
Ron Waksman
Thomas D. Weldon
Raphael F. Meloul
Richard A. Hillstead
Jonathan J. Rosen
George K. Bonnoitt
David S. Halpern
Charles E. Larsen
Ian R. Crocker
Emory University
Best Vascular, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novoste Corporation, Ron Waksman, Thomas D. Weldon, Raphael F. Meloul, Richard A. Hillstead, Jonathan J. Rosen, George K. Bonnoitt, David S. Halpern, Charles E. Larsen, Ian R. Crocker, Emory University, Best Vascular, Inc. filed Critical Novoste Corporation
Publication of CA2222706A1 publication Critical patent/CA2222706A1/en
Application granted granted Critical
Publication of CA2222706C publication Critical patent/CA2222706C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0069Devices for implanting pellets, e.g. markers or solid medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/1002Balloon catheters characterised by balloon shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1002Intraluminal radiation therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007Arrangements or means for the introduction of sources into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026Multi-lumen catheters with stationary elements
    • A61M2025/0037Multi-lumen catheters with stationary elements characterized by lumina being arranged side-by-side
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026Multi-lumen catheters with stationary elements
    • A61M2025/0039Multi-lumen catheters with stationary elements characterized by lumina being arranged coaxially
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026Multi-lumen catheters with stationary elements
    • A61M2025/004Multi-lumen catheters with stationary elements characterized by lumina being arranged circumferentially
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026Multi-lumen catheters with stationary elements
    • A61M25/0029Multi-lumen catheters with stationary elements characterized by features relating to least one lumen located at the middle part of the catheter, e.g. slots, flaps, valves, cuffs, apertures, notches, grooves or rapid exchange ports
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/1006Balloons formed between concentric tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1002Intraluminal radiation therapy
    • A61N2005/1003Intraluminal radiation therapy having means for centering a radioactive source within the lumen, e.g. balloons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1002Intraluminal radiation therapy
    • A61N2005/1005Intraluminal radiation therapy with asymmetrical radiation pattern
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007Arrangements or means for the introduction of sources into the body
    • A61N2005/1008Apparatus for temporary insertion of sources, e.g. afterloaders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N2005/1019Sources therefor
    • A61N2005/1023Means for creating a row of seeds, e.g. spacers

Abstract

Apparatus for delivery of a treatment element (22) such as a radiation source, through a catheter (92) to a desired site in the interluminal passageways of a patient, such as the coronary artery, for inhibiting the formation of scar tissue such as may occur in restenosis following balloon angioplasty.
One or more treatment elements (22), such as a capsule or pellet containing radioactive material, is positionable within the lumen (144) and movable between the proximal and distal end portions under the force of liquid flowing through the lumen. Balloon membrane (256) can be used for angioplasty.
CA002222706A 1996-04-04 1997-04-04 Radiation treatment of the vascular system Expired - Fee Related CA2222706C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/628,231 1996-04-04
US08/628,231 US5899882A (en) 1994-10-27 1996-04-04 Catheter apparatus for radiation treatment of a desired area in the vascular system of a patient
PCT/US1997/005538 WO1997037715A1 (en) 1994-10-27 1997-04-04 Radiation treatment of the vascular system

Publications (2)

Publication Number Publication Date
CA2222706A1 true CA2222706A1 (en) 1997-10-16
CA2222706C CA2222706C (en) 2007-06-05

Family

ID=24518029

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002222706A Expired - Fee Related CA2222706C (en) 1996-04-04 1997-04-04 Radiation treatment of the vascular system

Country Status (14)

Country Link
US (2) US5899882A (en)
EP (1) EP0836502B1 (en)
JP (1) JPH11506972A (en)
KR (1) KR19990022294A (en)
CN (1) CN1524592A (en)
AT (1) ATE317715T1 (en)
AU (1) AU716727B2 (en)
BR (1) BR9702360A (en)
CA (1) CA2222706C (en)
DE (1) DE69735263T2 (en)
NO (1) NO314243B1 (en)
RU (1) RU2177350C2 (en)
WO (1) WO1997037715A1 (en)
ZA (1) ZA972789B (en)

Families Citing this family (231)

* Cited by examiner, † Cited by third party
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DE69735263T2 (en) 2006-11-16
NO975588L (en) 1997-12-03
CA2222706C (en) 2007-06-05
CN1524592A (en) 2004-09-01
DE69735263D1 (en) 2006-04-20
AU2800297A (en) 1997-10-29
EP0836502A4 (en) 2001-04-18
KR19990022294A (en) 1999-03-25
NO975588D0 (en) 1997-12-03
AU716727B2 (en) 2000-03-02
EP0836502B1 (en) 2006-02-15
US5899882A (en) 1999-05-04
JPH11506972A (en) 1999-06-22
EP0836502A1 (en) 1998-04-22
RU2177350C2 (en) 2001-12-27
NO314243B1 (en) 2003-02-24
BR9702360A (en) 1999-12-28
ZA972789B (en) 1997-11-14
ATE317715T1 (en) 2006-03-15
WO1997037715A1 (en) 1997-10-16
US6306074B1 (en) 2001-10-23

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