CA2208230A1 - Controlled release formulation (albuterol) - Google Patents

Controlled release formulation (albuterol)

Info

Publication number
CA2208230A1
CA2208230A1 CA002208230A CA2208230A CA2208230A1 CA 2208230 A1 CA2208230 A1 CA 2208230A1 CA 002208230 A CA002208230 A CA 002208230A CA 2208230 A CA2208230 A CA 2208230A CA 2208230 A1 CA2208230 A1 CA 2208230A1
Authority
CA
Canada
Prior art keywords
albuterol
controlled release
release formulation
sustained release
pharmaceutical formulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002208230A
Other languages
French (fr)
Other versions
CA2208230C (en
Inventor
Anand R. Baichwal
Troy W. Mccall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Penwest Pharmaceuticals Co
Original Assignee
Anand R. Baichwal
Troy W. Mccall
Edward Mendell Co., Inc.
Penwest Pharmaceutical Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24207743&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2208230(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Anand R. Baichwal, Troy W. Mccall, Edward Mendell Co., Inc., Penwest Pharmaceutical Co. filed Critical Anand R. Baichwal
Publication of CA2208230A1 publication Critical patent/CA2208230A1/en
Application granted granted Critical
Publication of CA2208230C publication Critical patent/CA2208230C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/02Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075Macromolecular gels

Abstract

A sustained release pharmaceutical formulation and methods of making and using the same are provided. The sustained release pharmaceutical formulation includes a sustained release excipient including a gelling agent, an inert pharmaceutical diluent, an optional hydrophobic material and/or hydrophobic coating, and a medicament for sustained oral administration.
CA002208230A 1995-11-03 1996-11-04 Controlled release formulation (albuterol) Expired - Fee Related CA2208230C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/553,008 1995-11-03
US08/553,008 US5662933A (en) 1993-09-09 1995-11-03 Controlled release formulation (albuterol)
PCT/US1996/017991 WO1997016172A1 (en) 1995-11-03 1996-11-04 Controlled release formulation (albuterol)

Publications (2)

Publication Number Publication Date
CA2208230A1 true CA2208230A1 (en) 1997-05-09
CA2208230C CA2208230C (en) 2001-12-25

Family

ID=24207743

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002208230A Expired - Fee Related CA2208230C (en) 1995-11-03 1996-11-04 Controlled release formulation (albuterol)

Country Status (12)

Country Link
US (2) US5662933A (en)
EP (2) EP0804166B1 (en)
JP (1) JP3250737B2 (en)
KR (2) KR100264024B1 (en)
AT (1) ATE507820T1 (en)
AU (1) AU7725396A (en)
CA (1) CA2208230C (en)
DE (1) DE69638364D1 (en)
DK (1) DK0804166T3 (en)
ES (1) ES2366278T3 (en)
MX (1) MX9704910A (en)
WO (1) WO1997016172A1 (en)

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US6726930B1 (en) * 1993-09-09 2004-04-27 Penwest Pharmaceuticals Co. Sustained release heterodisperse hydrogel systems for insoluble drugs
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Also Published As

Publication number Publication date
AU7725396A (en) 1997-05-22
EP0804166B1 (en) 2011-05-04
DE69638364D1 (en) 2011-06-16
EP2286796A2 (en) 2011-02-23
ATE507820T1 (en) 2011-05-15
US5662933A (en) 1997-09-02
EP0804166A1 (en) 1997-11-05
WO1997016172A1 (en) 1997-05-09
KR100264024B1 (en) 2000-09-01
ES2366278T3 (en) 2011-10-18
MX9704910A (en) 1998-06-30
KR20000018064A (en) 2000-04-06
DK0804166T3 (en) 2011-08-15
EP0804166A4 (en) 2004-12-29
JPH10507210A (en) 1998-07-14
CA2208230C (en) 2001-12-25
JP3250737B2 (en) 2002-01-28
US5958456A (en) 1999-09-28
EP2286796A3 (en) 2012-02-22

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