CA2194062A1 - System for controlling tissue ablation using temperature sensors - Google Patents

System for controlling tissue ablation using temperature sensors

Info

Publication number
CA2194062A1
CA2194062A1 CA002194062A CA2194062A CA2194062A1 CA 2194062 A1 CA2194062 A1 CA 2194062A1 CA 002194062 A CA002194062 A CA 002194062A CA 2194062 A CA2194062 A CA 2194062A CA 2194062 A1 CA2194062 A1 CA 2194062A1
Authority
CA
Canada
Prior art keywords
emitter
tissue ablation
emitters
individually
temperature sensors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002194062A
Other languages
French (fr)
Other versions
CA2194062C (en
Inventor
Dorin Panescu
James G. Whayne
Sidney D. Fleischman
David K. Swanson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Scientific Ltd Barbados
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26952123&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2194062(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CA2194062A1 publication Critical patent/CA2194062A1/en
Application granted granted Critical
Publication of CA2194062C publication Critical patent/CA2194062C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206Generators therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1492Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01KMEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
    • G01K1/00Details of thermometers not specially adapted for particular types of thermometer
    • G01K1/02Means for indicating or recording specially adapted for thermometers
    • G01K1/026Means for indicating or recording specially adapted for thermometers arrangements for monitoring a plurality of temperatures, e.g. by multiplexing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01KMEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
    • G01K3/00Thermometers giving results other than momentary value of temperature
    • G01K3/08Thermometers giving results other than momentary value of temperature giving differences of values; giving differentiated values
    • G01K3/14Thermometers giving results other than momentary value of temperature giving differences of values; giving differentiated values in respect of space
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017Electrical control of surgical instruments
    • A61B2017/00022Sensing or detecting at the treatment site
    • A61B2017/00084Temperature
    • A61B2017/00088Temperature using thermistors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017Electrical control of surgical instruments
    • A61B2017/00022Sensing or detecting at the treatment site
    • A61B2017/00084Temperature
    • A61B2017/00092Temperature using thermocouples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017Electrical control of surgical instruments
    • A61B2017/00137Details of operation mode
    • A61B2017/00154Details of operation mode pulsed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00292Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
    • A61B2017/003Steerable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00059Material properties
    • A61B2018/00071Electrical conductivity
    • A61B2018/00083Electrical conductivity low, i.e. electrically insulating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00059Material properties
    • A61B2018/00089Thermal conductivity
    • A61B2018/00095Thermal conductivity high, i.e. heat conducting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00059Material properties
    • A61B2018/00089Thermal conductivity
    • A61B2018/00101Thermal conductivity low, i.e. thermally insulating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00107Coatings on the energy applicator
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00107Coatings on the energy applicator
    • A61B2018/00148Coatings on the energy applicator with metal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/0016Energy applicators arranged in a two- or three dimensional array
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345Vascular system
    • A61B2018/00351Heart
    • A61B2018/00357Endocardium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577Ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00642Sensing and controlling the application of energy with feedback, i.e. closed loop control
    • A61B2018/00654Sensing and controlling the application of energy with feedback, i.e. closed loop control with individual control of each of a plurality of energy emitting elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/0066Sensing and controlling the application of energy without feedback, i.e. open loop control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/0069Sensing and controlling the application of energy using fuzzy logic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00696Controlled or regulated parameters
    • A61B2018/00702Power or energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00696Controlled or regulated parameters
    • A61B2018/00726Duty cycle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00696Controlled or regulated parameters
    • A61B2018/00761Duration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00791Temperature
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00791Temperature
    • A61B2018/00797Temperature measured by multiple temperature sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00791Temperature
    • A61B2018/00803Temperature with temperature prediction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00791Temperature
    • A61B2018/00821Temperature measured by a thermocouple
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00886Duration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206Generators therefor
    • A61B2018/124Generators therefor switching the output to different electrodes, e.g. sequentially
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206Generators therefor
    • A61B2018/1246Generators therefor characterised by the output polarity
    • A61B2018/1253Generators therefor characterised by the output polarity monopolar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206Generators therefor
    • A61B2018/1246Generators therefor characterised by the output polarity
    • A61B2018/126Generators therefor characterised by the output polarity bipolar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206Generators therefor
    • A61B2018/128Generators therefor generating two or more frequencies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1467Probes or electrodes therefor using more than two electrodes on a single probe

Abstract

This invention is a system and associated method to ablate body tissue using multiple emitters (30) of ablating energy. The system and method convey ablating energy individually to each emitter (30) in a sequence of power pulses.
The system and method periodically sense the temperature of each emitter (30) and compare the sensed temperatures to a desired temperature established for all emitters (30) to generate a signal individually for each emitter (30) based upon the comparison. The system and method individually vary the power pulse to each emitter (30) based upon the signal for that emitter to maintain the temperatures of all emitters essentially at the desired temperature during tissue ablation.
CA002194062A 1994-06-27 1994-10-14 System for controlling tissue ablation using temperature sensors Expired - Fee Related CA2194062C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US26693494A 1994-06-27 1994-06-27
US08/266,934 1994-06-27
US28693094A 1994-08-08 1994-08-08
US08/286,930 1994-08-08
PCT/US1994/011748 WO1996000036A1 (en) 1994-06-27 1994-10-14 System for controlling tissue ablation using temperature sensors

Publications (2)

Publication Number Publication Date
CA2194062A1 true CA2194062A1 (en) 1996-01-04
CA2194062C CA2194062C (en) 2005-06-28

Family

ID=26952123

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002194062A Expired - Fee Related CA2194062C (en) 1994-06-27 1994-10-14 System for controlling tissue ablation using temperature sensors

Country Status (8)

Country Link
US (1) US5769847A (en)
EP (1) EP0768841B1 (en)
JP (2) JP3564141B2 (en)
AT (1) ATE255369T1 (en)
CA (1) CA2194062C (en)
DE (1) DE69433387T2 (en)
ES (1) ES2214493T3 (en)
WO (1) WO1996000036A1 (en)

Families Citing this family (321)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891095A (en) 1993-05-10 1999-04-06 Arthrocare Corporation Electrosurgical treatment of tissue in electrically conductive fluid
US6277112B1 (en) 1996-07-16 2001-08-21 Arthrocare Corporation Methods for electrosurgical spine surgery
US6024733A (en) * 1995-06-07 2000-02-15 Arthrocare Corporation System and method for epidermal tissue ablation
US5697882A (en) 1992-01-07 1997-12-16 Arthrocare Corporation System and method for electrosurgical cutting and ablation
US6355032B1 (en) 1995-06-07 2002-03-12 Arthrocare Corporation Systems and methods for selective electrosurgical treatment of body structures
US6142992A (en) 1993-05-10 2000-11-07 Arthrocare Corporation Power supply for limiting power in electrosurgery
US6235020B1 (en) 1993-05-10 2001-05-22 Arthrocare Corporation Power supply and methods for fluid delivery in electrosurgery
US6391025B1 (en) 1993-05-10 2002-05-21 Arthrocare Corporation Electrosurgical scalpel and methods for tissue cutting
JP3578460B2 (en) * 1994-06-27 2004-10-20 ボストン サイエンティフィック リミテッド Systems and methods for sensing body temperature
EP0768841B1 (en) 1994-06-27 2003-12-03 Boston Scientific Limited System for controlling tissue ablation using temperature sensors
US5810802A (en) 1994-08-08 1998-09-22 E.P. Technologies, Inc. Systems and methods for controlling tissue ablation using multiple temperature sensing elements
EP0957792A4 (en) * 1995-05-02 2000-09-20 Heart Rhythm Tech Inc System for controlling the energy delivered to a patient for ablation
US6149620A (en) 1995-11-22 2000-11-21 Arthrocare Corporation System and methods for electrosurgical tissue treatment in the presence of electrically conductive fluid
US7270661B2 (en) * 1995-11-22 2007-09-18 Arthocare Corporation Electrosurgical apparatus and methods for treatment and removal of tissue
US7758537B1 (en) 1995-11-22 2010-07-20 Arthrocare Corporation Systems and methods for electrosurgical removal of the stratum corneum
US5755760A (en) 1996-03-11 1998-05-26 Medtronic, Inc. Deflectable catheter
US6180867B1 (en) * 1996-04-17 2001-01-30 General Electric Company Thermal sensor array and methods of fabrication and use
US5987360A (en) * 1996-05-03 1999-11-16 Urologix, Inc. Axial preferential thermal therapy
US6066139A (en) * 1996-05-14 2000-05-23 Sherwood Services Ag Apparatus and method for sterilization and embolization
US5893885A (en) * 1996-11-01 1999-04-13 Cordis Webster, Inc. Multi-electrode ablation catheter
US5954719A (en) * 1996-12-11 1999-09-21 Irvine Biomedical, Inc. System for operating a RF ablation generator
US5916213A (en) * 1997-02-04 1999-06-29 Medtronic, Inc. Systems and methods for tissue mapping and ablation
US6652515B1 (en) * 1997-07-08 2003-11-25 Atrionix, Inc. Tissue ablation device assembly and method for electrically isolating a pulmonary vein ostium from an atrial wall
WO1999017672A1 (en) * 1997-10-06 1999-04-15 Somnus Medical Technologies, Inc. Electro-surgical instrument with a graphical user interface
DE19757720A1 (en) 1997-12-23 1999-06-24 Sulzer Osypka Gmbh Method for operating a high-frequency ablation device and device for high-frequency tissue ablation
US6517534B1 (en) 1998-02-11 2003-02-11 Cosman Company, Inc. Peri-urethral ablation
US6447505B2 (en) 1998-02-11 2002-09-10 Cosman Company, Inc. Balloon catheter method for intra-urethral radio-frequency urethral enlargement
US6440127B2 (en) 1998-02-11 2002-08-27 Cosman Company, Inc. Method for performing intraurethral radio-frequency urethral enlargement
US6355031B1 (en) * 1998-02-19 2002-03-12 Curon Medical, Inc. Control systems for multiple electrode arrays to create lesions in tissue regions at or near a sphincter
DE19817553A1 (en) 1998-04-15 1999-10-21 Biotronik Mess & Therapieg Ablation arrangement
US6059778A (en) 1998-05-05 2000-05-09 Cardiac Pacemakers, Inc. RF ablation apparatus and method using unipolar and bipolar techniques
US6558378B2 (en) 1998-05-05 2003-05-06 Cardiac Pacemakers, Inc. RF ablation system and method having automatic temperature control
US6042580A (en) * 1998-05-05 2000-03-28 Cardiac Pacemakers, Inc. Electrode having composition-matched, common-lead thermocouple wire for providing multiple temperature-sensitive junctions
US6312425B1 (en) * 1998-05-05 2001-11-06 Cardiac Pacemakers, Inc. RF ablation catheter tip electrode with multiple thermal sensors
US6251107B1 (en) * 1998-06-25 2001-06-26 Cardima, Inc. Ep catheter
US7276063B2 (en) 1998-08-11 2007-10-02 Arthrocare Corporation Instrument for electrosurgical tissue treatment
US6245065B1 (en) 1998-09-10 2001-06-12 Scimed Life Systems, Inc. Systems and methods for controlling power in an electrosurgical probe
WO2000015130A2 (en) * 1998-09-10 2000-03-23 Scimed Life Systems, Inc. Systems for controlling an ablation process performed with a heart electrocatheter
US6183468B1 (en) 1998-09-10 2001-02-06 Scimed Life Systems, Inc. Systems and methods for controlling power in an electrosurgical probe
US6123702A (en) * 1998-09-10 2000-09-26 Scimed Life Systems, Inc. Systems and methods for controlling power in an electrosurgical probe
US7364577B2 (en) 2002-02-11 2008-04-29 Sherwood Services Ag Vessel sealing system
US7901400B2 (en) * 1998-10-23 2011-03-08 Covidien Ag Method and system for controlling output of RF medical generator
US7137980B2 (en) 1998-10-23 2006-11-21 Sherwood Services Ag Method and system for controlling output of RF medical generator
US7194294B2 (en) 1999-01-06 2007-03-20 Scimed Life Systems, Inc. Multi-functional medical catheter and methods of use
US6206831B1 (en) 1999-01-06 2001-03-27 Scimed Life Systems, Inc. Ultrasound-guided ablation catheter and methods of use
US6702811B2 (en) 1999-04-05 2004-03-09 Medtronic, Inc. Ablation catheter assembly with radially decreasing helix and method of use
US6290699B1 (en) * 1999-07-07 2001-09-18 Uab Research Foundation Ablation tool for forming lesions in body tissue
US6315732B1 (en) 1999-07-20 2001-11-13 Scimed Life Systems, Inc. Imaging catheter and methods of use for ultrasound-guided ablation
US6517538B1 (en) * 1999-10-15 2003-02-11 Harold Jacob Temperature-controlled snare
WO2001037723A2 (en) * 1999-11-22 2001-05-31 Boston Scientific Limited Loop structures for supporting diagnostic and therapeutic elements in contact with body tissue
US6542781B1 (en) 1999-11-22 2003-04-01 Scimed Life Systems, Inc. Loop structures for supporting diagnostic and therapeutic elements in contact with body tissue
US6613046B1 (en) 1999-11-22 2003-09-02 Scimed Life Systems, Inc. Loop structures for supporting diagnostic and therapeutic elements in contact with body tissue
EP1112720B1 (en) * 1999-12-29 2005-08-31 Stockert, Rüdiger Device for treating biological tissues with high frequency currents
WO2001082812A1 (en) * 2000-04-27 2001-11-08 Medtronic, Inc. Vibration sensitive ablation apparatus and method
AU2001249874A1 (en) 2000-04-27 2001-11-12 Medtronic, Inc. System and method for assessing transmurality of ablation lesions
WO2001087172A1 (en) * 2000-05-12 2001-11-22 Cardima, Inc. Multi-channel rf energy delivery with coagulum reduction
ATE290827T1 (en) 2000-06-13 2005-04-15 Atrionix Inc SURGICAL ABLATION PROBE FOR FORMING AN ANNUAL LESION
US6511478B1 (en) * 2000-06-30 2003-01-28 Scimed Life Systems, Inc. Medical probe with reduced number of temperature sensor wires
US6425894B1 (en) * 2000-07-12 2002-07-30 Biosense Webster, Inc. Ablation catheter with electrode temperature monitoring
US6746446B1 (en) * 2000-08-04 2004-06-08 Cardima, Inc. Electrophysiological device for the isthmus
US7104987B2 (en) 2000-10-17 2006-09-12 Asthmatx, Inc. Control system and process for application of energy to airway walls and other mediums
US6752804B2 (en) 2000-12-28 2004-06-22 Cardiac Pacemakers, Inc. Ablation system and method having multiple-sensor electrodes to assist in assessment of electrode and sensor position and adjustment of energy levels
US6743226B2 (en) 2001-02-09 2004-06-01 Cosman Company, Inc. Adjustable trans-urethral radio-frequency ablation
US6692492B2 (en) * 2001-11-28 2004-02-17 Cardiac Pacemaker, Inc. Dielectric-coated ablation electrode having a non-coated window with thermal sensors
US7361830B2 (en) * 2002-03-21 2008-04-22 Rtd Company Polymer encapsulated micro-thermocouple
US20140018880A1 (en) 2002-04-08 2014-01-16 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US7653438B2 (en) 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
WO2003092520A1 (en) 2002-05-06 2003-11-13 Sherwood Services Ag Blood detector for controlling anesu and method therefor
US7572257B2 (en) 2002-06-14 2009-08-11 Ncontact Surgical, Inc. Vacuum coagulation and dissection probes
US7063698B2 (en) * 2002-06-14 2006-06-20 Ncontact Surgical, Inc. Vacuum coagulation probes
US9439714B2 (en) * 2003-04-29 2016-09-13 Atricure, Inc. Vacuum coagulation probes
US8235990B2 (en) 2002-06-14 2012-08-07 Ncontact Surgical, Inc. Vacuum coagulation probes
US6893442B2 (en) 2002-06-14 2005-05-17 Ablatrics, Inc. Vacuum coagulation probe for atrial fibrillation treatment
US6887237B2 (en) * 2002-07-22 2005-05-03 Medtronic, Inc. Method for treating tissue with a wet electrode and apparatus for using same
US7044948B2 (en) 2002-12-10 2006-05-16 Sherwood Services Ag Circuit for controlling arc energy from an electrosurgical generator
US7104985B2 (en) * 2003-03-06 2006-09-12 Martinelli Michael A Apparatus and method for causing selective necrosis of abnormal cells
US7722601B2 (en) 2003-05-01 2010-05-25 Covidien Ag Method and system for programming and controlling an electrosurgical generator system
EP1651127B1 (en) 2003-07-16 2012-10-31 Arthrocare Corporation Rotary electrosurgical apparatus
AU2004285412A1 (en) 2003-09-12 2005-05-12 Minnow Medical, Llc Selectable eccentric remodeling and/or ablation of atherosclerotic material
AU2003284929B2 (en) 2003-10-23 2010-07-22 Covidien Ag Redundant temperature monitoring in electrosurgical systems for safety mitigation
US8104956B2 (en) 2003-10-23 2012-01-31 Covidien Ag Thermocouple measurement circuit
US7396336B2 (en) 2003-10-30 2008-07-08 Sherwood Services Ag Switched resonant ultrasonic power amplifier system
US7131860B2 (en) 2003-11-20 2006-11-07 Sherwood Services Ag Connector systems for electrosurgical generator
US7300435B2 (en) * 2003-11-21 2007-11-27 Sherwood Services Ag Automatic control system for an electrosurgical generator
US7766905B2 (en) 2004-02-12 2010-08-03 Covidien Ag Method and system for continuity testing of medical electrodes
US7780662B2 (en) 2004-03-02 2010-08-24 Covidien Ag Vessel sealing system using capacitive RF dielectric heating
US8396548B2 (en) 2008-11-14 2013-03-12 Vessix Vascular, Inc. Selective drug delivery in a lumen
US9713730B2 (en) 2004-09-10 2017-07-25 Boston Scientific Scimed, Inc. Apparatus and method for treatment of in-stent restenosis
US9277955B2 (en) 2010-04-09 2016-03-08 Vessix Vascular, Inc. Power generating and control apparatus for the treatment of tissue
US7628786B2 (en) 2004-10-13 2009-12-08 Covidien Ag Universal foot switch contact port
US20060089637A1 (en) 2004-10-14 2006-04-27 Werneth Randell L Ablation catheter
US20090240249A1 (en) * 2004-11-08 2009-09-24 Cardima, Inc. System and Method for Performing Ablation and Other Medical Procedures Using An Electrode Array with Flexible Circuit
US8617152B2 (en) 2004-11-15 2013-12-31 Medtronic Ablation Frontiers Llc Ablation system with feedback
US7429261B2 (en) 2004-11-24 2008-09-30 Ablation Frontiers, Inc. Atrial ablation catheter and method of use
US7468062B2 (en) 2004-11-24 2008-12-23 Ablation Frontiers, Inc. Atrial ablation catheter adapted for treatment of septal wall arrhythmogenic foci and method of use
DE102005007769B4 (en) * 2005-02-19 2008-09-04 Bowa-Electronic Gmbh High frequency surgery device and method of operation therefor
US8182433B2 (en) * 2005-03-04 2012-05-22 Endosense Sa Medical apparatus system having optical fiber load sensing capability
WO2006092021A1 (en) * 2005-03-04 2006-09-08 Intervention Technology Pty Ltd A minimal device and method for effecting hyperthermia derived anaesthesia
US8075498B2 (en) 2005-03-04 2011-12-13 Endosense Sa Medical apparatus system having optical fiber load sensing capability
US7236567B2 (en) * 2005-03-24 2007-06-26 Siemens Aktiengesellschaft Method and apparatus for synchronizing operation of an x-ray system and a magnetic system
US9474564B2 (en) 2005-03-31 2016-10-25 Covidien Ag Method and system for compensating for external impedance of an energy carrying component when controlling an electrosurgical generator
US8932208B2 (en) 2005-05-26 2015-01-13 Maquet Cardiovascular Llc Apparatus and methods for performing minimally-invasive surgical procedures
US7850685B2 (en) 2005-06-20 2010-12-14 Medtronic Ablation Frontiers Llc Ablation catheter
US7655003B2 (en) 2005-06-22 2010-02-02 Smith & Nephew, Inc. Electrosurgical power control
EP1909679B1 (en) 2005-07-11 2013-11-20 Medtronic Ablation Frontiers LLC Low power tissue ablation system
US8894589B2 (en) 2005-08-01 2014-11-25 Endosense Sa Medical apparatus system having optical fiber load sensing capability
US7719400B1 (en) * 2005-08-02 2010-05-18 Rtd Company Method and apparatus for flexible temperature sensor having coiled element
US8657814B2 (en) 2005-08-22 2014-02-25 Medtronic Ablation Frontiers Llc User interface for tissue ablation system
US8734438B2 (en) 2005-10-21 2014-05-27 Covidien Ag Circuit and method for reducing stored energy in an electrosurgical generator
US8403925B2 (en) * 2006-12-06 2013-03-26 St. Jude Medical, Atrial Fibrillation Division, Inc. System and method for assessing lesions in tissue
US7947039B2 (en) 2005-12-12 2011-05-24 Covidien Ag Laparoscopic apparatus for performing electrosurgical procedures
US7691101B2 (en) 2006-01-06 2010-04-06 Arthrocare Corporation Electrosurgical method and system for treating foot ulcer
US8876746B2 (en) 2006-01-06 2014-11-04 Arthrocare Corporation Electrosurgical system and method for treating chronic wound tissue
JP2009527262A (en) * 2006-01-17 2009-07-30 エンディメド メディカル リミテッド Electrosurgical method and apparatus using phase controlled radio frequency energy
US9186200B2 (en) 2006-01-24 2015-11-17 Covidien Ag System and method for tissue sealing
US8685016B2 (en) 2006-01-24 2014-04-01 Covidien Ag System and method for tissue sealing
US8216223B2 (en) 2006-01-24 2012-07-10 Covidien Ag System and method for tissue sealing
US7513896B2 (en) 2006-01-24 2009-04-07 Covidien Ag Dual synchro-resonant electrosurgical apparatus with bi-directional magnetic coupling
CA2574935A1 (en) 2006-01-24 2007-07-24 Sherwood Services Ag A method and system for controlling an output of a radio-frequency medical generator having an impedance based control algorithm
US8147485B2 (en) 2006-01-24 2012-04-03 Covidien Ag System and method for tissue sealing
CA2574934C (en) 2006-01-24 2015-12-29 Sherwood Services Ag System and method for closed loop monitoring of monopolar electrosurgical apparatus
CA2575392C (en) 2006-01-24 2015-07-07 Sherwood Services Ag System and method for tissue sealing
US7651493B2 (en) 2006-03-03 2010-01-26 Covidien Ag System and method for controlling electrosurgical snares
US7648499B2 (en) 2006-03-21 2010-01-19 Covidien Ag System and method for generating radio frequency energy
US7651492B2 (en) 2006-04-24 2010-01-26 Covidien Ag Arc based adaptive control system for an electrosurgical unit
US8019435B2 (en) 2006-05-02 2011-09-13 Boston Scientific Scimed, Inc. Control of arterial smooth muscle tone
US8753334B2 (en) 2006-05-10 2014-06-17 Covidien Ag System and method for reducing leakage current in an electrosurgical generator
EP2020943B1 (en) 2006-05-30 2015-07-08 ArthroCare Corporation Hard tissue ablation system
US8567265B2 (en) 2006-06-09 2013-10-29 Endosense, SA Triaxial fiber optic force sensing catheter
US8048063B2 (en) * 2006-06-09 2011-11-01 Endosense Sa Catheter having tri-axial force sensor
EP2092957B2 (en) 2006-06-28 2019-11-20 Medtronic Ardian Luxembourg S.à.r.l. Systems for thermally-induced renal neuromodulation
US7731717B2 (en) 2006-08-08 2010-06-08 Covidien Ag System and method for controlling RF output during tissue sealing
US8034049B2 (en) 2006-08-08 2011-10-11 Covidien Ag System and method for measuring initial tissue impedance
US7794457B2 (en) 2006-09-28 2010-09-14 Covidien Ag Transformer for RF voltage sensing
EP2455034B1 (en) 2006-10-18 2017-07-19 Vessix Vascular, Inc. System for inducing desirable temperature effects on body tissue
CA2666661C (en) 2006-10-18 2015-01-20 Minnow Medical, Inc. Tuned rf energy and electrical tissue characterization for selective treatment of target tissues
JP5479901B2 (en) 2006-10-18 2014-04-23 べシックス・バスキュラー・インコーポレイテッド Induction of desired temperature effects on body tissue
EP2086441A4 (en) 2006-11-09 2012-04-25 Ncontact Surgical Inc Vacuum coagulation probes
GB2452103B (en) 2007-01-05 2011-08-31 Arthrocare Corp Electrosurgical system with suction control apparatus and system
WO2008125962A2 (en) * 2007-03-01 2008-10-23 Endymed Medical Ltd. Electrosurgical methods and devices employing semiconductor chips
US7862560B2 (en) 2007-03-23 2011-01-04 Arthrocare Corporation Ablation apparatus having reduced nerve stimulation and related methods
US8777941B2 (en) 2007-05-10 2014-07-15 Covidien Lp Adjustable impedance electrosurgical electrodes
US8641704B2 (en) 2007-05-11 2014-02-04 Medtronic Ablation Frontiers Llc Ablation therapy system and method for treating continuous atrial fibrillation
US8157789B2 (en) * 2007-05-24 2012-04-17 Endosense Sa Touch sensing catheter
US8622935B1 (en) 2007-05-25 2014-01-07 Endosense Sa Elongated surgical manipulator with body position and distal force sensing
US7834484B2 (en) 2007-07-16 2010-11-16 Tyco Healthcare Group Lp Connection cable and method for activating a voltage-controlled generator
US8216220B2 (en) 2007-09-07 2012-07-10 Tyco Healthcare Group Lp System and method for transmission of combined data stream
US8512332B2 (en) 2007-09-21 2013-08-20 Covidien Lp Real-time arc control in electrosurgical generators
WO2009045265A1 (en) 2007-10-05 2009-04-09 Maquet Cardiovascular, Llc Devices and methods for minimally-invasive surgical procedures
US9008793B1 (en) * 2007-10-15 2015-04-14 Chenes Llc Multiple electrode radiofrequency generator
JP5587786B2 (en) * 2007-12-06 2014-09-10 コーニンクレッカ フィリップス エヌ ヴェ Apparatus, method and computer program for applying energy to object
US9358063B2 (en) 2008-02-14 2016-06-07 Arthrocare Corporation Ablation performance indicator for electrosurgical devices
DK2268200T3 (en) * 2008-03-18 2019-01-07 Circa Scient Llc TEMPERATURE MEASURING EQUIPMENT WITH LARGE SURFACE AREA
US20090272905A1 (en) * 2008-05-05 2009-11-05 Roderick Bernhard Richards Wireless x-ray detector plate
US8298227B2 (en) * 2008-05-14 2012-10-30 Endosense Sa Temperature compensated strain sensing catheter
US8226639B2 (en) 2008-06-10 2012-07-24 Tyco Healthcare Group Lp System and method for output control of electrosurgical generator
US8747400B2 (en) 2008-08-13 2014-06-10 Arthrocare Corporation Systems and methods for screen electrode securement
US8364279B2 (en) 2008-09-25 2013-01-29 Boston Scientific Neuromodulation Corporation Electrical stimulation leads having RF compatibility and methods of use and manufacture
US8133219B2 (en) 2008-10-07 2012-03-13 Olympus Medical Systems Corp. High frequency operation apparatus and high frequency operation method
WO2010055455A1 (en) * 2008-11-11 2010-05-20 Koninklijke Philips Electronics N.V. Medical device comprising a probe for measuring temperature data in a patient's tissue
CN102271603A (en) 2008-11-17 2011-12-07 明诺医学股份有限公司 Selective accumulation of energy with or without knowledge of tissue topography
US8355799B2 (en) 2008-12-12 2013-01-15 Arthrocare Corporation Systems and methods for limiting joint temperature
US8262652B2 (en) 2009-01-12 2012-09-11 Tyco Healthcare Group Lp Imaginary impedance process monitoring and intelligent shut-off
US8574187B2 (en) 2009-03-09 2013-11-05 Arthrocare Corporation System and method of an electrosurgical controller with output RF energy control
US8430875B2 (en) * 2009-05-19 2013-04-30 Estech, Inc. (Endoscopic Technologies, Inc.) Magnetic navigation systems and methods
US8257350B2 (en) 2009-06-17 2012-09-04 Arthrocare Corporation Method and system of an electrosurgical controller with wave-shaping
US20110026562A1 (en) * 2009-07-31 2011-02-03 Rtd Company Temperature sensor using thin film resistance temperature detector
US9750563B2 (en) 2009-09-22 2017-09-05 Mederi Therapeutics, Inc. Systems and methods for treating tissue with radiofrequency energy
US10386990B2 (en) 2009-09-22 2019-08-20 Mederi Rf, Llc Systems and methods for treating tissue with radiofrequency energy
US9474565B2 (en) 2009-09-22 2016-10-25 Mederi Therapeutics, Inc. Systems and methods for treating tissue with radiofrequency energy
WO2011037621A2 (en) 2009-09-22 2011-03-31 Mederi Therapeutics Inc. Systems and methods for controlling use and operation of a family of different treatment devices
US9775664B2 (en) 2009-09-22 2017-10-03 Mederi Therapeutics, Inc. Systems and methods for treating tissue with radiofrequency energy
US8323279B2 (en) 2009-09-25 2012-12-04 Arthocare Corporation System, method and apparatus for electrosurgical instrument with movable fluid delivery sheath
US8317786B2 (en) 2009-09-25 2012-11-27 AthroCare Corporation System, method and apparatus for electrosurgical instrument with movable suction sheath
US20110118731A1 (en) * 2009-11-16 2011-05-19 Tyco Healthcare Group Lp Multi-Phase Electrode
US8372067B2 (en) 2009-12-09 2013-02-12 Arthrocare Corporation Electrosurgery irrigation primer systems and methods
US8668686B2 (en) * 2009-12-23 2014-03-11 Biosense Webster (Israel) Ltd. Sensing contact of ablation catheter using differential temperature measurements
US20110172659A1 (en) * 2010-01-13 2011-07-14 Vivant Medical, Inc. Ablation Device With User Interface at Device Handle, System Including Same, and Method of Ablating Tissue Using Same
US20110208180A1 (en) * 2010-02-25 2011-08-25 Vivant Medical, Inc. System and Method for Monitoring Ablation Size
US8556891B2 (en) * 2010-03-03 2013-10-15 Medtronic Ablation Frontiers Llc Variable-output radiofrequency ablation power supply
US8747399B2 (en) 2010-04-06 2014-06-10 Arthrocare Corporation Method and system of reduction of low frequency muscle stimulation during electrosurgical procedures
US9192790B2 (en) 2010-04-14 2015-11-24 Boston Scientific Scimed, Inc. Focused ultrasonic renal denervation
US8696659B2 (en) 2010-04-30 2014-04-15 Arthrocare Corporation Electrosurgical system and method having enhanced temperature measurement
US20120123400A1 (en) * 2010-05-10 2012-05-17 David Francischelli Methods and devices for controlling energy during ablation
US8473067B2 (en) 2010-06-11 2013-06-25 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
US9155589B2 (en) 2010-07-30 2015-10-13 Boston Scientific Scimed, Inc. Sequential activation RF electrode set for renal nerve ablation
US9408661B2 (en) 2010-07-30 2016-08-09 Patrick A. Haverkost RF electrodes on multiple flexible wires for renal nerve ablation
US9463062B2 (en) 2010-07-30 2016-10-11 Boston Scientific Scimed, Inc. Cooled conductive balloon RF catheter for renal nerve ablation
US9084609B2 (en) 2010-07-30 2015-07-21 Boston Scientific Scime, Inc. Spiral balloon catheter for renal nerve ablation
US9358365B2 (en) 2010-07-30 2016-06-07 Boston Scientific Scimed, Inc. Precision electrode movement control for renal nerve ablation
US8568405B2 (en) 2010-10-15 2013-10-29 Arthrocare Corporation Electrosurgical wand and related method and system
US8685018B2 (en) 2010-10-15 2014-04-01 Arthrocare Corporation Electrosurgical wand and related method and system
USD658760S1 (en) 2010-10-15 2012-05-01 Arthrocare Corporation Wound care electrosurgical wand
EP3449856B1 (en) 2010-10-25 2023-06-28 Medtronic Ardian Luxembourg S.à.r.l. Device for evaluation and feedback of neuromodulation treatment
WO2012061164A1 (en) 2010-10-25 2012-05-10 Kevin Mauch Catheter apparatuses having multi-electrode arrays for renal neuromodulation and associated systems and methods
US8974451B2 (en) 2010-10-25 2015-03-10 Boston Scientific Scimed, Inc. Renal nerve ablation using conductive fluid jet and RF energy
US9220558B2 (en) 2010-10-27 2015-12-29 Boston Scientific Scimed, Inc. RF renal denervation catheter with multiple independent electrodes
US9028485B2 (en) 2010-11-15 2015-05-12 Boston Scientific Scimed, Inc. Self-expanding cooling electrode for renal nerve ablation
US9089350B2 (en) 2010-11-16 2015-07-28 Boston Scientific Scimed, Inc. Renal denervation catheter with RF electrode and integral contrast dye injection arrangement
US9668811B2 (en) 2010-11-16 2017-06-06 Boston Scientific Scimed, Inc. Minimally invasive access for renal nerve ablation
US9326751B2 (en) 2010-11-17 2016-05-03 Boston Scientific Scimed, Inc. Catheter guidance of external energy for renal denervation
US9060761B2 (en) 2010-11-18 2015-06-23 Boston Scientific Scime, Inc. Catheter-focused magnetic field induced renal nerve ablation
US9023034B2 (en) 2010-11-22 2015-05-05 Boston Scientific Scimed, Inc. Renal ablation electrode with force-activatable conduction apparatus
US9192435B2 (en) 2010-11-22 2015-11-24 Boston Scientific Scimed, Inc. Renal denervation catheter with cooled RF electrode
US20120157993A1 (en) 2010-12-15 2012-06-21 Jenson Mark L Bipolar Off-Wall Electrode Device for Renal Nerve Ablation
US9737353B2 (en) 2010-12-16 2017-08-22 Biosense Webster (Israel) Ltd. System for controlling tissue ablation using temperature sensors
US9220561B2 (en) 2011-01-19 2015-12-29 Boston Scientific Scimed, Inc. Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury
US9131597B2 (en) 2011-02-02 2015-09-08 Arthrocare Corporation Electrosurgical system and method for treating hard body tissue
WO2012142588A1 (en) 2011-04-14 2012-10-18 Endosense S.A. Compact force sensor for catheters
US10959775B2 (en) 2011-06-06 2021-03-30 Cosman Instruments, Llc Cool RF electrode
US10639101B2 (en) 2011-06-06 2020-05-05 Cosman Instruments, Llc Cool RF electrode
AU2012283908B2 (en) 2011-07-20 2017-02-16 Boston Scientific Scimed, Inc. Percutaneous devices and methods to visualize, target and ablate nerves
WO2013016203A1 (en) 2011-07-22 2013-01-31 Boston Scientific Scimed, Inc. Nerve modulation system with a nerve modulation element positionable in a helical guide
US9247985B2 (en) 2011-07-27 2016-02-02 Biosense Webster (Israel) Ltd. Test jig for ablator
EP2765942B1 (en) 2011-10-10 2016-02-24 Boston Scientific Scimed, Inc. Medical devices including ablation electrodes
US9420955B2 (en) 2011-10-11 2016-08-23 Boston Scientific Scimed, Inc. Intravascular temperature monitoring system and method
US10085799B2 (en) 2011-10-11 2018-10-02 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US9364284B2 (en) 2011-10-12 2016-06-14 Boston Scientific Scimed, Inc. Method of making an off-wall spacer cage
EP2768563B1 (en) 2011-10-18 2016-11-09 Boston Scientific Scimed, Inc. Deflectable medical devices
US9079000B2 (en) 2011-10-18 2015-07-14 Boston Scientific Scimed, Inc. Integrated crossing balloon catheter
EP2775948B1 (en) 2011-11-08 2018-04-04 Boston Scientific Scimed, Inc. Ostial renal nerve ablation
EP2779929A1 (en) 2011-11-15 2014-09-24 Boston Scientific Scimed, Inc. Device and methods for renal nerve modulation monitoring
US9119632B2 (en) 2011-11-21 2015-09-01 Boston Scientific Scimed, Inc. Deflectable renal nerve ablation catheter
US9265969B2 (en) 2011-12-21 2016-02-23 Cardiac Pacemakers, Inc. Methods for modulating cell function
WO2013096913A2 (en) 2011-12-23 2013-06-27 Vessix Vascular, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
WO2013101452A1 (en) 2011-12-28 2013-07-04 Boston Scientific Scimed, Inc. Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements
US9050106B2 (en) 2011-12-29 2015-06-09 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US10076383B2 (en) 2012-01-25 2018-09-18 Covidien Lp Electrosurgical device having a multiplexer
US9192308B2 (en) * 2012-03-27 2015-11-24 Covidien Lp Microwave-shielded tissue sensor probe
KR101942027B1 (en) * 2012-03-28 2019-04-11 삼성전자 주식회사 Method for predicting temperature in device
WO2013165584A1 (en) * 2012-05-04 2013-11-07 St. Jude Medical, Atrial Fibrillation Division, Inc. System and method for controlling delivery of ablation energy to tissue
US10660703B2 (en) 2012-05-08 2020-05-26 Boston Scientific Scimed, Inc. Renal nerve modulation devices
BR112014028131A2 (en) 2012-05-11 2017-06-27 Medtronic Ardian Luxembourg catheter apparatus, renal neuromodulation system, and method for performing renal neuromodulation
EP2854682B1 (en) 2012-06-04 2021-06-23 Boston Scientific Scimed, Inc. Systems for treating tissue of a passageway within a body
US10321946B2 (en) 2012-08-24 2019-06-18 Boston Scientific Scimed, Inc. Renal nerve modulation devices with weeping RF ablation balloons
US20140064334A1 (en) * 2012-09-06 2014-03-06 General Electric Company Measurement rake with a two piece cylindrical mast
EP2895095A2 (en) 2012-09-17 2015-07-22 Boston Scientific Scimed, Inc. Self-positioning electrode system and method for renal nerve modulation
US10549127B2 (en) 2012-09-21 2020-02-04 Boston Scientific Scimed, Inc. Self-cooling ultrasound ablation catheter
US10398464B2 (en) 2012-09-21 2019-09-03 Boston Scientific Scimed, Inc. System for nerve modulation and innocuous thermal gradient nerve block
JP6074051B2 (en) 2012-10-10 2017-02-01 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Intravascular neuromodulation system and medical device
US9095321B2 (en) 2012-11-21 2015-08-04 Medtronic Ardian Luxembourg S.A.R.L. Cryotherapeutic devices having integral multi-helical balloons and methods of making the same
US9713489B2 (en) 2013-03-07 2017-07-25 Arthrocare Corporation Electrosurgical methods and systems
US9693818B2 (en) 2013-03-07 2017-07-04 Arthrocare Corporation Methods and systems related to electrosurgical wands
US9956033B2 (en) 2013-03-11 2018-05-01 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
WO2014143571A1 (en) 2013-03-11 2014-09-18 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9808311B2 (en) 2013-03-13 2017-11-07 Boston Scientific Scimed, Inc. Deflectable medical devices
US9801678B2 (en) 2013-03-13 2017-10-31 Arthrocare Corporation Method and system of controlling conductive fluid flow during an electrosurgical procedure
CN105228546B (en) 2013-03-15 2017-11-14 波士顿科学国际有限公司 Utilize the impedance-compensated medicine equipment and method that are used to treat hypertension
US9561070B2 (en) * 2013-03-15 2017-02-07 St. Jude Medical, Cardiology Division, Inc. Ablation system, methods, and controllers
US10265122B2 (en) 2013-03-15 2019-04-23 Boston Scientific Scimed, Inc. Nerve ablation devices and related methods of use
JP6220044B2 (en) 2013-03-15 2017-10-25 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Medical device for renal nerve ablation
US9775663B2 (en) * 2013-03-15 2017-10-03 St. Jude Medical, Cardiology Division, Inc. Ablation system, methods, and controllers
US9179974B2 (en) 2013-03-15 2015-11-10 Medtronic Ardian Luxembourg S.A.R.L. Helical push wire electrode
JP2016524949A (en) 2013-06-21 2016-08-22 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Medical device for renal nerve ablation having a rotatable shaft
US9943365B2 (en) 2013-06-21 2018-04-17 Boston Scientific Scimed, Inc. Renal denervation balloon catheter with ride along electrode support
US9707036B2 (en) 2013-06-25 2017-07-18 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation using localized indifferent electrodes
WO2015002787A1 (en) 2013-07-01 2015-01-08 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
EP3019106A1 (en) 2013-07-11 2016-05-18 Boston Scientific Scimed, Inc. Medical device with stretchable electrode assemblies
US10660698B2 (en) 2013-07-11 2020-05-26 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation
EP3049007B1 (en) 2013-07-19 2019-06-12 Boston Scientific Scimed, Inc. Spiral bipolar electrode renal denervation balloon
CN103330578B (en) * 2013-07-19 2015-05-27 乐普(北京)医疗器械股份有限公司 Approximate-circumference type ultrasonic ablation catheter
WO2015013205A1 (en) 2013-07-22 2015-01-29 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
US10695124B2 (en) 2013-07-22 2020-06-30 Boston Scientific Scimed, Inc. Renal nerve ablation catheter having twist balloon
US9872719B2 (en) 2013-07-24 2018-01-23 Covidien Lp Systems and methods for generating electrosurgical energy using a multistage power converter
US9636165B2 (en) 2013-07-29 2017-05-02 Covidien Lp Systems and methods for measuring tissue impedance through an electrosurgical cable
CN105338917B (en) 2013-08-02 2018-02-06 奥林巴斯株式会社 Bio-tissue mating system, treatment apparatus control device
JP6159888B2 (en) 2013-08-22 2017-07-05 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Flexible circuit with improved adhesion to renal neuromodulation balloon
US9895194B2 (en) 2013-09-04 2018-02-20 Boston Scientific Scimed, Inc. Radio frequency (RF) balloon catheter having flushing and cooling capability
US20150073515A1 (en) 2013-09-09 2015-03-12 Medtronic Ardian Luxembourg S.a.r.I. Neuromodulation Catheter Devices and Systems Having Energy Delivering Thermocouple Assemblies and Associated Methods
CN105530885B (en) 2013-09-13 2020-09-22 波士顿科学国际有限公司 Ablation balloon with vapor deposited covering
WO2015057521A1 (en) 2013-10-14 2015-04-23 Boston Scientific Scimed, Inc. High resolution cardiac mapping electrode array catheter
US11246654B2 (en) 2013-10-14 2022-02-15 Boston Scientific Scimed, Inc. Flexible renal nerve ablation devices and related methods of use and manufacture
EP3057520A1 (en) 2013-10-15 2016-08-24 Boston Scientific Scimed, Inc. Medical device balloon
US9770606B2 (en) 2013-10-15 2017-09-26 Boston Scientific Scimed, Inc. Ultrasound ablation catheter with cooling infusion and centering basket
JP6259099B2 (en) 2013-10-18 2018-01-10 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Balloon catheter comprising a conductive wire with flexibility, and related uses and manufacturing methods
US10433902B2 (en) 2013-10-23 2019-10-08 Medtronic Ardian Luxembourg S.A.R.L. Current control methods and systems
CN105658163B (en) 2013-10-25 2020-08-18 波士顿科学国际有限公司 Embedded thermocouple in denervation flexible circuit
CN105636513B (en) 2013-10-31 2020-05-12 波士顿科学医学有限公司 Medical device for high resolution mapping using local matching
US10076258B2 (en) 2013-11-01 2018-09-18 Boston Scientific Scimed, Inc. Cardiac mapping using latency interpolation
US11096736B2 (en) * 2013-12-09 2021-08-24 Biosense Webster (Israel) Ltd. Pericardial catheter with temperature sensing array
WO2015103617A1 (en) 2014-01-06 2015-07-09 Boston Scientific Scimed, Inc. Tear resistant flex circuit assembly
US11000679B2 (en) 2014-02-04 2021-05-11 Boston Scientific Scimed, Inc. Balloon protection and rewrapping devices and related methods of use
EP3102136B1 (en) 2014-02-04 2018-06-27 Boston Scientific Scimed, Inc. Alternative placement of thermal sensors on bipolar electrode
US10130413B2 (en) * 2014-02-11 2018-11-20 Covidien Lp Temperature-sensing electrically-conductive tissue-contacting plate and methods of manufacturing same
US9526556B2 (en) 2014-02-28 2016-12-27 Arthrocare Corporation Systems and methods systems related to electrosurgical wands with screen electrodes
WO2015134276A1 (en) 2014-03-07 2015-09-11 Boston Scientific Scimed, Inc. Medical devices for mapping cardiac tissue
US9687167B2 (en) 2014-03-11 2017-06-27 Boston Scientific Scimed, Inc. Medical devices for mapping cardiac tissue
US9956035B2 (en) 2014-03-27 2018-05-01 Biosense Webster (Israel) Ltd. Temperature measurement in catheter
US20150300888A1 (en) * 2014-04-21 2015-10-22 National Taiwan University Temperature prediction system and method thereof
JP2017513600A (en) 2014-04-24 2017-06-01 メドトロニック アーディアン ルクセンブルク ソシエテ ア レスポンサビリテ リミテ Nerve adjustment catheter with braided shaft and related systems and methods
US10610292B2 (en) 2014-04-25 2020-04-07 Medtronic Ardian Luxembourg S.A.R.L. Devices, systems, and methods for monitoring and/or controlling deployment of a neuromodulation element within a body lumen and related technology
US10342606B2 (en) 2014-05-06 2019-07-09 Cosman Instruments, Llc Electrosurgical generator
US10136943B1 (en) 2014-10-21 2018-11-27 Cosman Instruments, Llc Electrosurgical system
US20150342671A1 (en) 2014-05-29 2015-12-03 Biosense Webster (Israel) Ltd. Catheter electrode with multiple thermocouples
JP2016007333A (en) * 2014-06-24 2016-01-18 株式会社グッドマン Electrode member for ablation and catheter for ablation
US9597142B2 (en) 2014-07-24 2017-03-21 Arthrocare Corporation Method and system related to electrosurgical procedures
US9649148B2 (en) 2014-07-24 2017-05-16 Arthrocare Corporation Electrosurgical system and method having enhanced arc prevention
US10194971B2 (en) 2014-09-26 2019-02-05 Cosman Medical, Inc. Electrosurgical generator
JP6673598B2 (en) 2014-11-19 2020-03-25 エピックス セラピューティクス,インコーポレイテッド High resolution mapping of tissue with pacing
SG11201703943VA (en) 2014-11-19 2017-06-29 Advanced Cardiac Therapeutics Inc Ablation devices, systems and methods of using a high-resolution electrode assembly
EP3220844B1 (en) 2014-11-19 2020-11-11 EPiX Therapeutics, Inc. Systems for high-resolution mapping of tissue
US9636164B2 (en) 2015-03-25 2017-05-02 Advanced Cardiac Therapeutics, Inc. Contact sensing systems and methods
EP3777745A1 (en) 2015-03-31 2021-02-17 St. Jude Medical, Cardiology Division, Inc. Methods and devices for delivering pulsed rf energy during catheter ablation
US10285754B2 (en) * 2015-05-18 2019-05-14 Biosense Webster (Israel) Ltd. Catheter with coaxial thermocouple
US10285752B2 (en) * 2015-12-07 2019-05-14 Biosense Webster (Israel) Ltd. Multilayer split ablation electrode
EP3376986B1 (en) 2016-01-07 2020-02-19 St. Jude Medical International Holding S.à r.l. Medical device with multi-core fiber for optical sensing
CA3017269A1 (en) 2016-03-15 2017-09-21 Epix Therapeutics, Inc. Improved devices, systems and methods for irrigated ablation
JP6622425B2 (en) * 2016-03-21 2019-12-18 セント・ジュード・メディカル,カーディオロジー・ディヴィジョン,インコーポレイテッド Multi-point thermocouple assembly with reduced number of wires
US10933250B2 (en) 2016-04-22 2021-03-02 Syneron Medical Ltd. Skin treatment apparatus and method
US11484711B2 (en) 2016-07-26 2022-11-01 The Cleveland Clinic Foundation Stereo-thermo-lesioning to treat a patient's neurological condition
JP6718557B2 (en) 2016-10-04 2020-07-08 セント・ジュード・メディカル,カーディオロジー・ディヴィジョン,インコーポレイテッド Ablation catheter tip
JP6866110B2 (en) * 2016-10-31 2021-04-28 日本ライフライン株式会社 Catheter for measuring esophageal temperature
CN110809448B (en) 2017-04-27 2022-11-25 Epix疗法公司 Determining properties of contact between catheter tip and tissue
WO2018200254A2 (en) 2017-04-28 2018-11-01 Stryker Corporation Control console and accessories for rf nerve ablation and methods of operating the same
US20210045805A1 (en) * 2019-08-15 2021-02-18 Biosense Webster (Israel) Ltd. Dynamic ablation and sensing according to contact of segmented electrodes
US11253720B2 (en) 2020-02-29 2022-02-22 Cutera, Inc. Dermatological systems and methods with handpiece for coaxial pulse delivery and temperature sensing
US10864380B1 (en) 2020-02-29 2020-12-15 Cutera, Inc. Systems and methods for controlling therapeutic laser pulse duration
CN111728691B (en) * 2020-07-07 2022-12-27 昆山雷盛医疗科技有限公司 Catheter-type thermal ablation therapeutic apparatus and contact condition detection method thereof
CN117500449A (en) * 2021-06-16 2024-02-02 柯惠有限合伙公司 Surgical systems and methods for predicting and/or controlling thermal spread using temperature
CN115177361A (en) * 2022-08-18 2022-10-14 上海美杰医疗科技有限公司 Temperature control system and method for multiple radio frequency ablation needles
WO2024042964A1 (en) * 2022-08-23 2024-02-29 株式会社トップ High frequency treatment device

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1248059B (en) 1964-09-01 1967-08-24 Schering Ag Process for the production of bradykinin-active undeca and dodecapeptides
US4565200A (en) * 1980-09-24 1986-01-21 Cosman Eric R Universal lesion and recording electrode system
US4411266A (en) * 1980-09-24 1983-10-25 Cosman Eric R Thermocouple radio frequency lesion electrode
US4413633A (en) * 1981-06-01 1983-11-08 Yanda Roman L Method and apparatus for monitoring body conditions
US4681122A (en) * 1985-09-23 1987-07-21 Victory Engineering Corp. Stereotaxic catheter for microwave thermotherapy
US4935345A (en) * 1987-04-07 1990-06-19 Arizona Board Of Regents Implantable microelectronic biochemical sensor incorporating thin film thermopile
US4860744A (en) * 1987-11-02 1989-08-29 Raj K. Anand Thermoelectrically controlled heat medical catheter
US4907589A (en) * 1988-04-29 1990-03-13 Cosman Eric R Automatic over-temperature control apparatus for a therapeutic heating device
US5178620A (en) * 1988-06-10 1993-01-12 Advanced Angioplasty Products, Inc. Thermal dilatation catheter and method
US4998933A (en) * 1988-06-10 1991-03-12 Advanced Angioplasty Products, Inc. Thermal angioplasty catheter and method
US4960109A (en) * 1988-06-21 1990-10-02 Massachusetts Institute Of Technology Multi-purpose temperature sensing probe for hyperthermia therapy
US5249585A (en) * 1988-07-28 1993-10-05 Bsd Medical Corporation Urethral inserted applicator for prostate hyperthermia
US5191883A (en) * 1988-10-28 1993-03-09 Prutech Research And Development Partnership Ii Device for heating tissue in a patient's body
US4966597A (en) * 1988-11-04 1990-10-30 Cosman Eric R Thermometric cardiac tissue ablation electrode with ultra-sensitive temperature detection
DE3838840C2 (en) * 1988-11-17 1997-02-20 Leibinger Gmbh High frequency coagulation device for surgical purposes
US5057105A (en) * 1989-08-28 1991-10-15 The University Of Kansas Med Center Hot tip catheter assembly
US5254088A (en) 1990-02-02 1993-10-19 Ep Technologies, Inc. Catheter steering mechanism
US5122137A (en) * 1990-04-27 1992-06-16 Boston Scientific Corporation Temperature controlled rf coagulation
US5156151A (en) * 1991-02-15 1992-10-20 Cardiac Pathways Corporation Endocardial mapping and ablation system and catheter probe
JP3091253B2 (en) 1991-04-25 2000-09-25 オリンパス光学工業株式会社 Thermal treatment equipment
US5383917A (en) 1991-07-05 1995-01-24 Jawahar M. Desai Device and method for multi-phase radio-frequency ablation
AU3128593A (en) * 1991-11-08 1993-06-07 Ep Technologies Inc Radiofrequency ablation with phase sensitive power detection
US5906614A (en) 1991-11-08 1999-05-25 Ep Technologies, Inc. Tissue heating and ablation systems and methods using predicted temperature for monitoring and control
US5366443A (en) * 1992-01-07 1994-11-22 Thapliyal And Eggers Partners Method and apparatus for advancing catheters through occluded body lumens
US5573533A (en) * 1992-04-10 1996-11-12 Medtronic Cardiorhythm Method and system for radiofrequency ablation of cardiac tissue
US5277201A (en) 1992-05-01 1994-01-11 Vesta Medical, Inc. Endometrial ablation apparatus and method
US5391199A (en) * 1993-07-20 1995-02-21 Biosense, Inc. Apparatus and method for treating cardiac arrhythmias
US5496312A (en) * 1993-10-07 1996-03-05 Valleylab Inc. Impedance and temperature generator control
EP0768841B1 (en) 1994-06-27 2003-12-03 Boston Scientific Limited System for controlling tissue ablation using temperature sensors

Also Published As

Publication number Publication date
US5769847A (en) 1998-06-23
WO1996000036A1 (en) 1996-01-04
JPH10505252A (en) 1998-05-26
JP3564141B2 (en) 2004-09-08
EP0768841A1 (en) 1997-04-23
DE69433387D1 (en) 2004-01-15
EP0768841B1 (en) 2003-12-03
DE69433387T2 (en) 2004-10-07
EP0768841A4 (en) 1998-05-06
JP2004148131A (en) 2004-05-27
CA2194062C (en) 2005-06-28
ES2214493T3 (en) 2004-09-16
ATE255369T1 (en) 2003-12-15

Similar Documents

Publication Publication Date Title
CA2194062A1 (en) System for controlling tissue ablation using temperature sensors
WO1993020770A3 (en) Radiofrequency system for ablation of cardiac tissue
EP0358114A3 (en) Aerosol delivery articles utilizing electrical energy
CA2294927A1 (en) Circumferential ablation device assembly and method
AU1727399A (en) Left atrium ablation catheter and method
AU6326298A (en) Electrode for electrosurgical ablation of tissue and method of manufacturing thesame
EP0868884A3 (en) Apparatus and method for catheter ablation
EP0664990A3 (en) Improved electrophysiological mapping and ablation catheter and method
AU3617893A (en) Electrosurgical catheter instrument with impacting working head
CA2242356A1 (en) Methods and apparatus for myocardial revascularization
WO1996036860A3 (en) Systems and methods for sensing sub-surface temperatures in body tissue during ablation with actively cooled electrodes
AU7869694A (en) Mapping and ablation system, catheter and method
AU7729296A (en) Atrioventricular valve tissue ablation catheter and method
AU2871795A (en) Cardiac tissue ablation device
CA2194061A1 (en) Systems and methods for sensing temperature within the body
AU8149198A (en) Method and apparatus for temperature control of biologic tissue with simultaneous irradiation
AUPN957296A0 (en) A system for simultaneous unipolar multi-electrode ablation
AU2722588A (en) Thermoelectrically controlled heat medical catheter
HUP9900502A3 (en) 8-cyano-1-cyclopropyl-7-(2,8-diazabicyclo-[4,3,0]-nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolin carboxylic acids and their derivatives, use and medicaments thereof and process producing them
GB2313534B (en) Control of a semi-mounted plough
CA2194072A1 (en) Tissue heating and ablation system
IL86085A0 (en) Head end control and steering system using a forward end maneuvering gas generator
WO1997040882A3 (en) Systems and methods for optimizing the delivery of radio frequency energy for lesion formation within human tissue
EP0909126A4 (en) Improved concentrated heat agricultural flame cultivator apparatus
AU609160B2 (en) Method of sterilizing anthers using thiocarboxylic acids and derivatives thereof

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed