US5663180A
(en)
*
|
1983-10-29 |
1997-09-02 |
G.D. Searle & Co. |
Substituted cyclopentenes for the treatment of inflammation
|
US6492413B2
(en)
*
|
1993-01-15 |
2002-12-10 |
G.D. Searle & Co. |
3.4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents
|
WO1994015932A1
(en)
*
|
1993-01-15 |
1994-07-21 |
G.D. Searle & Co. |
Novel 3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents
|
GB9420616D0
(en)
*
|
1994-10-12 |
1994-11-30 |
Merck Sharp & Dohme |
Method, compositions and use
|
US6090834A
(en)
*
|
1993-05-21 |
2000-07-18 |
G.D. Searle & Co. |
Substituted oxazoles for the treatment of inflammation
|
US5840746A
(en)
*
|
1993-06-24 |
1998-11-24 |
Merck Frosst Canada, Inc. |
Use of inhibitors of cyclooxygenase in the treatment of neurodegenerative diseases
|
GB9602877D0
(en)
*
|
1996-02-13 |
1996-04-10 |
Merck Frosst Canada Inc |
3,4-Diaryl-2-hydroxy-2,5- dihydrofurans as prodrugs to cox-2 inhibitors
|
US5474995A
(en)
*
|
1993-06-24 |
1995-12-12 |
Merck Frosst Canada, Inc. |
Phenyl heterocycles as cox-2 inhibitors
|
AU1269495A
(en)
*
|
1994-01-10 |
1995-08-01 |
Merck Frosst Canada Inc. |
Phenyl heterocycles as cox-2 inhibitors
|
CA2195847A1
(en)
*
|
1994-07-27 |
1996-02-08 |
John J. Talley |
Substituted thiazoles for the treatment of inflammation
|
US5620999A
(en)
*
|
1994-07-28 |
1997-04-15 |
Weier; Richard M. |
Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation
|
US6613789B2
(en)
|
1994-07-28 |
2003-09-02 |
G. D. Searle & Co. |
Heterocyclo-substituted imidazoles for the treatment of inflammation
|
US5616601A
(en)
*
|
1994-07-28 |
1997-04-01 |
Gd Searle & Co |
1,2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation
|
US6426360B1
(en)
*
|
1994-07-28 |
2002-07-30 |
G D Searle & Co. |
4,5-substituted imidazolyl compounds for the treatment of inflammation
|
US6239172B1
(en)
*
|
1997-04-10 |
2001-05-29 |
Nitrosystems, Inc. |
Formulations for treating disease and methods of using same
|
GB2294879A
(en)
*
|
1994-10-19 |
1996-05-15 |
Merck & Co Inc |
Cylcooxygenase-2 Inhibitors
|
ES2139959T3
(en)
*
|
1994-10-27 |
2000-02-16 |
Merck Frosst Canada Inc |
STYLENE DERIVATIVES USEFUL AS CYCLOOXYGENASE-2 INHIBITORS.
|
JP2636819B2
(en)
|
1994-12-20 |
1997-07-30 |
日本たばこ産業株式会社 |
Oxazole-based heterocyclic aromatic compounds
|
CA2206978A1
(en)
*
|
1994-12-21 |
1996-06-27 |
Merck Frosst Canada Inc. |
Diaryl-2-(5h)-furanones as cox-2 inhibitors
|
US5633272A
(en)
*
|
1995-02-13 |
1997-05-27 |
Talley; John J. |
Substituted isoxazoles for the treatment of inflammation
|
EP0809636B1
(en)
*
|
1995-02-13 |
2002-09-04 |
G.D. Searle & Co. |
Substituted isoxazoles for the treatment of inflammation
|
US5691374A
(en)
*
|
1995-05-18 |
1997-11-25 |
Merck Frosst Canada Inc. |
Diaryl-5-oxygenated-2-(5H) -furanones as COX-2 inhibitors
|
US6512121B2
(en)
|
1998-09-14 |
2003-01-28 |
G.D. Searle & Co. |
Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
US5643933A
(en)
*
|
1995-06-02 |
1997-07-01 |
G. D. Searle & Co. |
Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
US6515014B2
(en)
|
1995-06-02 |
2003-02-04 |
G. D. Searle & Co. |
Thiophene substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
CA2223154A1
(en)
|
1995-06-02 |
1996-12-05 |
G.D. Searle & Co. |
Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
US6156776A
(en)
*
|
1995-06-08 |
2000-12-05 |
Yu; Dingwei Tim |
Diaryl substituted thiazoles useful in the treatment of fungal infections
|
US5700816A
(en)
*
|
1995-06-12 |
1997-12-23 |
Isakson; Peter C. |
Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitor and a leukotriene A4 hydrolase inhibitor
|
ATE301457T1
(en)
*
|
1995-06-12 |
2005-08-15 |
Searle & Co |
AGENT CONTAINING A CYCLOOXYGENASE-2 INHIBITOR AND A 5-LIPOXYGENASE INHIBITOR
|
US6342510B1
(en)
|
1995-06-12 |
2002-01-29 |
G. D. Searle & Co. |
Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitors and a leukotriene B4 receptor antagonist
|
US6593361B2
(en)
|
1995-07-19 |
2003-07-15 |
Merck & Co Inc |
Method of treating colonic adenomas
|
US5968974A
(en)
|
1995-07-19 |
1999-10-19 |
Merck & Co., Inc. |
Method of treating colonic adenomas
|
US5837719A
(en)
*
|
1995-08-10 |
1998-11-17 |
Merck & Co., Inc. |
2,5-substituted aryl pyrroles, compositions containing such compounds and methods of use
|
US5792778A
(en)
*
|
1995-08-10 |
1998-08-11 |
Merck & Co., Inc. |
2-substituted aryl pyrroles, compositions containing such compounds and methods of use
|
US5786515A
(en)
*
|
1995-09-15 |
1998-07-28 |
Merck & Co., Inc. |
Synthesis of α-chloro or fluoro ketones
|
EP0853481A1
(en)
*
|
1995-09-27 |
1998-07-22 |
Merck Frosst Canada Inc. |
Compositions for treating inflammation containing certain prostaglandins and a selective cyclooxygenase-2 inhibitor
|
US5717100A
(en)
*
|
1995-10-06 |
1998-02-10 |
Merck & Co., Inc. |
Substituted imidazoles having anti-cancer and cytokine inhibitory activity
|
US6083949A
(en)
*
|
1995-10-06 |
2000-07-04 |
Merck & Co., Inc. |
Substituted imidazoles having anti-cancer and cytokine inhibitory activity
|
US5981576A
(en)
*
|
1995-10-13 |
1999-11-09 |
Merck Frosst Canada, Inc. |
(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors
|
UA57002C2
(en)
*
|
1995-10-13 |
2003-06-16 |
Мерк Фросст Кенада Енд Ко./Мерк Фросст Кенада Енд Сі. |
(methylsulfonyl)phenyl-2-(5n)-furanon derivative, a pharmaceutical composition and a method for treatment
|
US6020343A
(en)
*
|
1995-10-13 |
2000-02-01 |
Merck Frosst Canada, Inc. |
(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors
|
AU716582B2
(en)
*
|
1995-10-17 |
2000-03-02 |
G.D. Searle & Co. |
Method of detecting cyclooxygenase-2
|
DE69618820T2
(en)
*
|
1995-10-30 |
2002-06-20 |
Merck Frosst Canada Inc |
3,4-DIARYL-2-HYDROXY-2,5-DIHYDROFURANE AS AN ACTIVE SUBSTANCE OF COX-2 INHIBITORS
|
US6222048B1
(en)
*
|
1995-12-18 |
2001-04-24 |
Merck Frosst Canada & Co. |
Diaryl-2-(5H)-furanones as Cox-2 inhibitors
|
NZ327022A
(en)
*
|
1996-01-26 |
1999-06-29 |
Searle & Co |
Heterocyclo-substituted imidazoles for the treatment of inflammation
|
HUP9902119A3
(en)
*
|
1996-02-01 |
2001-08-28 |
Merck Frosst Canada & Co Kirkl |
Diphenyl stilbene derivatives as cox-2 inhibitors and pharmaceutical compositions of the same
|
DE69702182T2
(en)
*
|
1996-02-01 |
2001-03-01 |
Merck Frosst Canada Inc |
ALKYLATED STYROLE AS PRODRUGS TO COX-2 INHIBITORS
|
US5789413A
(en)
*
|
1996-02-01 |
1998-08-04 |
Merck Frosst Canada, Inc. |
Alkylated styrenes as prodrugs to COX-2 inhibitors
|
US5733909A
(en)
*
|
1996-02-01 |
1998-03-31 |
Merck Frosst Canada, Inc. |
Diphenyl stilbenes as prodrugs to COX-2 inhibitors
|
DK0888127T3
(en)
|
1996-02-13 |
2002-04-08 |
Searle & Co |
Combinations with immunosuppressive effects containing cyclooxygenase-2 inhibitors and 5-lipooxygenase inhibitors
|
DE69733338T2
(en)
|
1996-02-13 |
2006-03-16 |
G.D. Searle & Co., Chicago |
PREPARATIONS, CONTAINING A CYCLOOXYGENASE-2 INHIBITOR AND A LEUKOTRIEN B4 RECEPTOR ANTAGONIST
|
DE69715382T2
(en)
|
1996-02-13 |
2003-04-30 |
Searle & Co |
DRUG COMBINATIONS WITH IMMUNOSUPPRESSIVE EFFECTS WHICH CONTAIN CYCLOOXYGENASE-2 INHIBITORS AND LEUKOTRIES LTA4 HYDRASE INHIBITORS
|
HUP9902645A3
(en)
*
|
1996-03-18 |
1999-12-28 |
Eisai Co Ltd |
Fused-ring carboxylic acid derivatives
|
EP0889878B1
(en)
*
|
1996-03-29 |
2002-09-04 |
Merck Frosst Canada & Co. |
Bisarylcyclobutene derivates as cyclooxygenase inhibitors
|
US6180651B1
(en)
*
|
1996-04-04 |
2001-01-30 |
Bristol-Myers Squibb |
Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics
|
US5807873A
(en)
*
|
1996-04-04 |
1998-09-15 |
Laboratories Upsa |
Diarylmethylidenefuran derivatives and their uses in therapeutics
|
FR2747123B1
(en)
*
|
1996-04-04 |
1998-06-26 |
Union Pharma Scient Appl |
NOVEL DIARYLMETHYLIDENE TETRAHYDROFURANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THERAPEUTIC USES
|
US5908858A
(en)
|
1996-04-05 |
1999-06-01 |
Sankyo Company, Limited |
1,2-diphenylpyrrole derivatives, their preparation and their therapeutic uses
|
ES2311571T3
(en)
|
1996-04-12 |
2009-02-16 |
G.D. Searle Llc |
BENCENOSULFONAMIDE DERIVATIVES SUBSTITUTED AS COX-2 INHIBITORS PROFARMS.
|
EP0900201A1
(en)
*
|
1996-04-23 |
1999-03-10 |
Merck Frosst Canada Inc. |
Pyridinyl-2-cyclopenten-1-ones as selective cyclooxygenase-2 inhibitors
|
US5922742A
(en)
*
|
1996-04-23 |
1999-07-13 |
Merck Frosst Canada |
Pyridinyl-2-cyclopenten-1-ones as selective cyclooxygenase-2 inhibitors
|
WO1997044028A1
(en)
*
|
1996-05-17 |
1997-11-27 |
Merck & Co., Inc. |
Compositions for a once a day treatment of cyclooxygenase-2 mediated diseases
|
WO1997044027A1
(en)
*
|
1996-05-17 |
1997-11-27 |
Merck & Co., Inc. |
Compositions for a once a day treatment of cyclooxygenase-2 mediated diseases
|
AU775030B2
(en)
*
|
1996-05-17 |
2004-07-15 |
Merck Frosst Company |
Compositions for a once a day treatment of cyclooxygenase-2 mediated diseases
|
US6677364B2
(en)
|
1998-04-20 |
2004-01-13 |
G.D. Searle & Co. |
Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
US5883267A
(en)
*
|
1996-05-31 |
1999-03-16 |
Merck & Co., Inc. |
Process for making phenyl heterocycles useful as cox-2 inhibitors
|
HRP970289A2
(en)
*
|
1996-05-31 |
1998-04-30 |
Merck & Co Inc |
Process for preparing phenyl heterocycles useful as cox-2 inhibitors
|
JP3418624B2
(en)
*
|
1996-06-10 |
2003-06-23 |
メルク エンド カンパニー インコーポレーテッド |
Substituted imidazoles having cytokine inhibitory activity
|
GB9615867D0
(en)
*
|
1996-07-03 |
1996-09-11 |
Merck & Co Inc |
Process of preparing phenyl heterocycles useful as cox-2 inhibitors
|
US5677318A
(en)
*
|
1996-07-11 |
1997-10-14 |
Merck Frosst Canada, Inc. |
Diphenyl-1,2-3-thiadiazoles as anti-inflammatory agents
|
ES2188971T3
(en)
|
1996-08-14 |
2003-07-01 |
Searle & Co |
CRYSTAL FORM OF THE 4- (5-METHYL-3-PHENYLISOXAZOL-4-IL) BENZENSULFONAMIDE.
|
US6586458B1
(en)
*
|
1996-08-16 |
2003-07-01 |
Pozen Inc. |
Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
|
US8022095B2
(en)
*
|
1996-08-16 |
2011-09-20 |
Pozen, Inc. |
Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
|
US5939069A
(en)
*
|
1996-08-23 |
1999-08-17 |
University Of Florida |
Materials and methods for detection and treatment of immune system dysfunctions
|
FR2753449B1
(en)
*
|
1996-09-13 |
1998-12-04 |
Union Pharma Scient Appl |
NOVEL 3,4-DIARYLOXAZOLONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THERAPEUTIC USES
|
EP0932402B1
(en)
|
1996-10-15 |
2004-07-21 |
G.D. Searle LLC |
Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia
|
US5776954A
(en)
*
|
1996-10-30 |
1998-07-07 |
Merck & Co., Inc. |
Substituted pyridyl pyrroles, compositions containing such compounds and methods of use
|
US5985930A
(en)
*
|
1996-11-21 |
1999-11-16 |
Pasinetti; Giulio M. |
Treatment of neurodegenerative conditions with nimesulide
|
DE69725171T2
(en)
*
|
1996-12-10 |
2004-07-15 |
G.D. Searle & Co., Chicago |
SUBSTITUTED PYRROLYL COMPOUNDS FOR TREATING INFLAMMATION
|
EP0863134A1
(en)
*
|
1997-03-07 |
1998-09-09 |
Merck Frosst Canada Inc. |
2-(3,5-difluorophenyl)-3-(4-(methyl-sulfonyl)phenyl)-2-cyclopenten-1-one useful as an inhibitor of cyclooxygenase-2
|
ATE244232T1
(en)
*
|
1997-03-14 |
2003-07-15 |
Merck Frosst Canada Inc |
(METHYLSULFONYL)PHENYL-2-(5H)-FURANONE WITH OXYGEN BINDING AS A COX-2 INHIBITOR
|
US6004960A
(en)
*
|
1997-03-14 |
1999-12-21 |
Merck Frosst Canada, Inc. |
Pyridazinones as inhibitors of cyclooxygenase-2
|
AU738727B2
(en)
*
|
1997-03-14 |
2001-09-27 |
Merck Frosst Canada Ltd. |
Pyridazinones as inhibitors of cyclooxygenase-2
|
US6071954A
(en)
*
|
1997-03-14 |
2000-06-06 |
Merk Frosst Canada, Inc. |
(methylsulfonyl)phenyl-2-(5H)-furanones with oxygen link as COX-2 inhibitors
|
US6130334A
(en)
*
|
1998-04-15 |
2000-10-10 |
Merck & Co., Inc. |
Process for making 2-aryl-3-aryl-5-halo pyridines useful as COX-2 inhibitors
|
US6127545A
(en)
*
|
1997-04-18 |
2000-10-03 |
Merck & Co., Inc. |
Process for making 2-aryl-3-aryl-5-halo pyridines useful as COX-2 inhibitors
|
TW492959B
(en)
*
|
1997-04-18 |
2002-07-01 |
Merck & Co Inc |
Process for making 2-aryl-3-aryl-5-halo pyridines useful as cox-2 inhibitors
|
US20040072889A1
(en)
*
|
1997-04-21 |
2004-04-15 |
Pharmacia Corporation |
Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
|
US6525053B1
(en)
|
1997-08-22 |
2003-02-25 |
Abbott Laboratories |
Prostaglandin endoperoxide H synthase biosynthesis inhibitors
|
US6307047B1
(en)
*
|
1997-08-22 |
2001-10-23 |
Abbott Laboratories |
Prostaglandin endoperoxide H synthase biosynthesis inhibitors
|
YU11900A
(en)
|
1997-09-05 |
2002-11-15 |
Glaxo Group Limited |
2,3-diaryl-pyrazolo (1,5-b)pyridazines derivatives their preparation and their use as cyclooxygenase 2(cox-2) inhibitors
|
US6004950A
(en)
*
|
1997-09-12 |
1999-12-21 |
Merck Frosst Canada, Inc. |
2-aminopyridines as inhibitors of cyclooxygenase-2
|
ES2239402T3
(en)
*
|
1997-09-12 |
2005-09-16 |
MERCK FROSST CANADA & CO. |
2-AMINOPIRIDINS AS INHIBITORS OF CYCLOOXYGENASA-2.
|
RS49982B
(en)
|
1997-09-17 |
2008-09-29 |
Euro-Celtique S.A., |
Synergistic analgesic combination of opioid analgesic and cyclooxygenase-2 inhibitor
|
US6034089A
(en)
*
|
1997-10-03 |
2000-03-07 |
Merck & Co., Inc. |
Aryl thiophene derivatives as PDE IV inhibitors
|
US6020339A
(en)
*
|
1997-10-03 |
2000-02-01 |
Merck & Co., Inc. |
Aryl furan derivatives as PDE IV inhibitors
|
FR2769311B1
(en)
*
|
1997-10-07 |
1999-12-24 |
Union Pharma Scient Appl |
NOVEL 3,4-DIARYLTHIAZOLIN-2-ONE OR -2-THIONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES
|
US5972986A
(en)
*
|
1997-10-14 |
1999-10-26 |
G.D. Searle & Co. |
Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia
|
US6080876A
(en)
*
|
1997-10-29 |
2000-06-27 |
Merck & Co., Inc. |
Process for making phenyl heterocycles useful as COX-2 inhibitors
|
WO1999023087A1
(en)
*
|
1997-10-30 |
1999-05-14 |
Merck Frosst Canada & Co. |
Diaryl-5-alkyl-5-methyl-2(5h)-furanones as selective cyclooxygenase-2 inhibitors
|
US6133292A
(en)
*
|
1997-10-30 |
2000-10-17 |
Merck Frosst Canada & Co. |
Diaryl-5-alkyl-5-methyl-2-(5H)-furanones as selective cyclooxygenase-2-inhibitors
|
BR9813164A
(en)
*
|
1997-10-31 |
2000-08-22 |
Searle & Co |
Method of using cyclooxygenase-2 inhibitors to maintain the fetal arterial duct during treatment and prevent premature labor pains
|
US6025353A
(en)
*
|
1997-11-19 |
2000-02-15 |
G.D. Searle & Co. |
Method of using cyclooxygenase-2 inhibitors as anti-angiogenic agents
|
CA2313049A1
(en)
|
1997-12-17 |
1999-06-24 |
Cornell Research Foundation, Inc. |
Cyclooxygenase-2 inhibition
|
US7041694B1
(en)
|
1997-12-17 |
2006-05-09 |
Cornell Research Foundation, Inc. |
Cyclooxygenase-2 inhibition
|
US6375957B1
(en)
*
|
1997-12-22 |
2002-04-23 |
Euro-Celtique, S.A. |
Opioid agonist/opioid antagonist/acetaminophen combinations
|
WO1999032119A1
(en)
|
1997-12-22 |
1999-07-01 |
Euro-Celtique, S.A. |
Opioid agonist/antagonist combinations
|
US6887893B1
(en)
*
|
1997-12-24 |
2005-05-03 |
Sankyo Company, Limited |
Methods and compositions for treatment and prevention of tumors, tumor-related disorders and cachexia
|
FR2775477B1
(en)
*
|
1998-02-27 |
2000-05-19 |
Union Pharma Scient Appl |
NOVEL HETEROCYCLIC DIARYLMETHYLENE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES
|
US6136804A
(en)
|
1998-03-13 |
2000-10-24 |
Merck & Co., Inc. |
Combination therapy for treating, preventing, or reducing the risks associated with acute coronary ischemic syndrome and related conditions
|
US6727238B2
(en)
|
1998-06-11 |
2004-04-27 |
Pfizer Inc. |
Sulfonylbenzene compounds as anti-inflammatory/analgesic agents
|
TNSN99111A1
(en)
*
|
1998-06-11 |
2005-11-10 |
Pfizer |
NOVEL SULFONYLBENZENE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
|
US6294558B1
(en)
|
1999-05-31 |
2001-09-25 |
Pfizer Inc. |
Sulfonylbenzene compounds as anti-inflammatory/analgesic agents
|
AU754719B2
(en)
*
|
1998-08-31 |
2002-11-21 |
Merck & Co., Inc. |
Method of treating neurodegenerative diseases
|
DE19842833B4
(en)
|
1998-09-18 |
2005-04-14 |
Merckle Gmbh |
2-Arylalkylthio-imidazoles, 2-Arylalkenylthio-imidazoles and 2-Arylalkinylthio-imidazole as anti-inflammatory and inhibitors of cytokine release
|
CA2347768A1
(en)
*
|
1998-10-27 |
2000-05-04 |
Merck & Co., Inc. |
Synthesis of methylthiophenyl hydroxyketones
|
AU759307B2
(en)
*
|
1998-11-02 |
2003-04-10 |
Merck Sharp & Dohme Corp. |
Method of treating migraines and pharmaceutical compositions
|
CA2349567A1
(en)
|
1998-11-03 |
2000-05-11 |
Glaxo Group Limited |
Pyrazolopyridine derivatives as selective cox-2 inhibitors
|
SA99191255B1
(en)
|
1998-11-30 |
2006-11-25 |
جي دي سيرل اند كو |
celecoxib compounds
|
US6649645B1
(en)
|
1998-12-23 |
2003-11-18 |
Pharmacia Corporation |
Combination therapy of radiation and a COX-2 inhibitor for treatment of neoplasia
|
US20040122011A1
(en)
*
|
1998-12-23 |
2004-06-24 |
Pharmacia Corporation |
Method of using a COX-2 inhibitor and a TACE inhibitors as a combination therapy
|
US20030013739A1
(en)
*
|
1998-12-23 |
2003-01-16 |
Pharmacia Corporation |
Methods of using a combination of cyclooxygenase-2 selective inhibitors and thalidomide for the treatment of neoplasia
|
US6155267A
(en)
*
|
1998-12-31 |
2000-12-05 |
Medtronic, Inc. |
Implantable medical device monitoring method and system regarding same
|
DE60041808D1
(en)
*
|
1999-01-27 |
2009-04-30 |
Cornell Res Foundation Inc |
TREATMENT OF CANCER WITH HER-2 / NEU OVEREXPRIMATION
|
US6498166B1
(en)
|
1999-02-27 |
2002-12-24 |
Smithkline Beecham Corporation |
Pyrazolopyridines
|
US6277873B1
(en)
|
1999-03-25 |
2001-08-21 |
Dingwei Tim Yu |
Oxadiazole antifungal agents
|
KR20010094161A
(en)
*
|
2000-04-04 |
2001-10-31 |
서경배 |
2,2-Dimethyl-4,5-diaryl- 3(2H)furanone derivatives and selective cyclooxygenase-2 inhibitors and a pharmaceutical composition thereof
|
ES2213007T3
(en)
*
|
1999-04-14 |
2004-08-16 |
Pacific Corporation |
DERIVATIVES OF 4,5-DIARIL-3 (2H) -FURANONE AS INHIBITORS OF CYCLLOXYGENASA-2.
|
CO5261541A1
(en)
*
|
1999-05-14 |
2003-03-31 |
Pfizer Prod Inc |
COMBINATION THERAPY FOR THE TREATMENT OF MIGRANA
|
CO5190664A1
(en)
|
1999-06-30 |
2002-08-29 |
Pfizer Prod Inc |
COMBINATION THERAPY FOR THE TREATMENT OF MIGRANA ADMINISTRATION OF A 5HT RECEPTOR, CAFFEINE AND A CYCLLOXYGENASA-2 INHIBITOR
|
US6066667A
(en)
*
|
1999-08-17 |
2000-05-23 |
Ashbrook; Charles D. |
Substituted furanones, compositions and antiarthritic use
|
AU6976400A
(en)
*
|
1999-09-08 |
2001-04-10 |
Merck Frosst Canada & Co. |
1,2,3-thiadiazoles and their use as cox-2 inhibitors
|
EP1216037A2
(en)
*
|
1999-09-21 |
2002-06-26 |
Emory University |
Methods and compositions for treating platelet-related disorders using mpl pathway inhibitory agents
|
PT1090915E
(en)
*
|
1999-10-08 |
2009-08-03 |
Merial Sas |
Polymorphic b form of 3-(cyclopropylmethoxy)-4-¬-4-(methylsulfonyl)phenyl - 5,5-dimethyl-5h-furan-2-one
|
EP1099695A1
(en)
*
|
1999-11-09 |
2001-05-16 |
Laboratoire Theramex S.A. |
5-aryl-1H-1,2,4-triazole compounds as inhibitors of cyclooxygenase-2 and pharmaceutical compositions containing them
|
EP1104759B1
(en)
|
1999-12-03 |
2003-10-22 |
Pfizer Products Inc. |
Heteroaryl phenyl pyrazole compounds as anti-inflammatory/analgesic agents
|
CA2326970C
(en)
|
1999-12-03 |
2004-11-23 |
Pfizer Products Inc. |
Acetylene derivatives as anti-inflammatory/analgesic agents
|
PT1104760E
(en)
|
1999-12-03 |
2003-06-30 |
Pfizer Prod Inc |
SULFAMOYL-HETEROARILPIRAZOLE COMPOUNDS AS ANALGESIC AND ANTI-INFLAMMATORY AGENTS
|
YU35102A
(en)
|
1999-12-03 |
2005-03-15 |
Pfizer Products Inc. |
Heterocyclo-alkylsulfonyl pyrazole derivatives as anti- inflammatory/analgesic agents
|
PT1150960E
(en)
*
|
1999-12-08 |
2005-06-30 |
Pharmacia Corp |
CELECOXIB POLYMORIC CRYSTALLINE FORMS
|
SK12672001A3
(en)
|
1999-12-08 |
2002-04-04 |
Pharmacia Corporation |
Compositions of cyclooxygenase-2 inhibitor having rapid onset of therapeutic effect
|
UA74539C2
(en)
|
1999-12-08 |
2006-01-16 |
Pharmacia Corp |
Crystalline polymorphous forms of celecoxib (variants), a method for the preparation thereof (variants), a pharmaceutical composition (variants)
|
GB9930358D0
(en)
|
1999-12-22 |
2000-02-09 |
Glaxo Group Ltd |
Process for the preparation of chemical compounds
|
AP2002002582A0
(en)
*
|
1999-12-23 |
2002-09-30 |
Nitromed Inc |
Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use
|
DE10001166A1
(en)
|
2000-01-13 |
2001-07-19 |
Merckle Gmbh |
Fused pyrrole compounds, pharmaceutical compositions containing them and their use
|
DE60138535D1
(en)
|
2000-02-04 |
2009-06-10 |
Children S Hospital Res Founda |
USE OF LYSOSOMAL ACID LIPASE FOR THE TREATMENT OF ATHEROSCLEROSIS AND SIMILAR DISEASES
|
CA2400578C
(en)
|
2000-02-08 |
2007-01-02 |
Euro-Celtique, S.A. |
Controlled-release compositions containing opioid agonist and antagonist
|
HU229705B1
(en)
|
2000-02-08 |
2014-05-28 |
Euro Celtique Sa |
Tamper-resistant oral opioid agonist formulations
|
ES2166710B1
(en)
*
|
2000-04-25 |
2004-10-16 |
J. URIACH & CIA, S.A. |
NEW HETEROCICLIC COMPOUNDS WITH ANTI-INFLAMMATORY ACTIVITY.
|
WO2001081332A2
(en)
*
|
2000-04-25 |
2001-11-01 |
Pharmacia Corporation |
2-fluorobenzenesulfonyl compounds for the treatment of inflammation
|
WO2001090097A2
(en)
*
|
2000-05-22 |
2001-11-29 |
Dr. Reddy's Research Foundation |
Novel compounds having antiinflammatory activity: process for their preparation and pharmaceutical compositions containing them
|
AU6837701A
(en)
|
2000-06-13 |
2001-12-24 |
American Home Prod |
Analgesic and anti-inflammatory compositions containing cox-2 inhibitors
|
US6465509B2
(en)
*
|
2000-06-30 |
2002-10-15 |
Merck Frosst Canada & Co. |
Pyrones as inhibitors of cyclooxygenase-2
|
PE20020146A1
(en)
*
|
2000-07-13 |
2002-03-31 |
Upjohn Co |
OPHTHALMIC FORMULATION INCLUDING A CYCLOOXYGENASE-2 (COX-2) INHIBITOR
|
JP2004503601A
(en)
*
|
2000-07-13 |
2004-02-05 |
ファルマシア・コーポレーション |
Use of COX-2 inhibitors in the treatment and prevention of ocular COX-2-mediated diseases
|
AU7090201A
(en)
*
|
2000-07-20 |
2002-02-05 |
Lauras As |
Method
|
US6716829B2
(en)
|
2000-07-27 |
2004-04-06 |
Pharmacia Corporation |
Aldosterone antagonist and cyclooxygenase-2 inhibitor combination therapy to prevent or treat inflammation-related cardiovascular disorders
|
PE20020506A1
(en)
|
2000-08-22 |
2002-07-09 |
Glaxo Group Ltd |
PIRAZOLE DERIVATIVES FUSED AS PROTEIN KINASE INHIBITORS
|
AU2001285334A1
(en)
*
|
2000-08-29 |
2002-03-13 |
Peter Van Patten |
Combination for the treatment of migraine comprising a cyclooxygenase-2 inhibitor and acetylsalicylic acid
|
GB0021494D0
(en)
*
|
2000-09-01 |
2000-10-18 |
Glaxo Group Ltd |
Chemical comkpounds
|
US20030219461A1
(en)
*
|
2000-09-12 |
2003-11-27 |
Britten Nancy J. |
Parenteral combination therapy for infective conditions
|
AU2001295038A1
(en)
*
|
2000-09-18 |
2002-03-26 |
Merck & Co., Inc. |
Treatment of inflammation with a combination of a cyclooxygenase-2 inhibitor and an integrin alpha-V antagonist
|
DE10057366A1
(en)
*
|
2000-11-18 |
2002-05-23 |
Mahle Gmbh |
Method for producing a piston with cooled ring carrier
|
DE60112609T2
(en)
|
2000-12-15 |
2006-01-19 |
Glaxo Group Ltd., Greenford |
pyrazolopyridines
|
EP1377573B1
(en)
|
2000-12-15 |
2005-07-27 |
Glaxo Group Limited |
Pyrazolopyridine derivatives
|
WO2002060378A2
(en)
|
2000-12-21 |
2002-08-08 |
Nitromed, Inc. |
Substituted aryl compounds as cyclooxygenase-2 selective inhibitors, compositions and methods of use
|
US7115565B2
(en)
*
|
2001-01-18 |
2006-10-03 |
Pharmacia & Upjohn Company |
Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
|
AUPR283801A0
(en)
*
|
2001-02-01 |
2001-03-01 |
Australian National University, The |
Chemical compounds and methods
|
EP1363669A2
(en)
*
|
2001-02-02 |
2003-11-26 |
Pharmacia Corporation |
Method of using a cyclooxygenase-2 inhibitor and sex steroids as a combination therapy for the treatment and prevention of dismenorrhea
|
DE10107683A1
(en)
|
2001-02-19 |
2002-08-29 |
Merckle Gmbh Chem Pharm Fabrik |
2-Thio-substituted imidazole derivatives and their use in pharmacy
|
ES2227451T3
(en)
|
2001-03-08 |
2005-04-01 |
Smithkline Beecham Corporation |
DERIVATIVES OF PIRAZOLOPIRIDINE.
|
EP1372643A1
(en)
|
2001-03-30 |
2004-01-02 |
Smithkline Beecham Corporation |
Pyrazolopyridines, process for their preparation and use as therapeutic compounds
|
MY137736A
(en)
|
2001-04-03 |
2009-03-31 |
Pharmacia Corp |
Reconstitutable parenteral composition
|
ES2266487T3
(en)
|
2001-04-10 |
2007-03-01 |
Smithkline Beecham Corporation |
ANTIVIRAL PIRAZOLOPIRINE COMPOUNDS.
|
US20030105144A1
(en)
|
2001-04-17 |
2003-06-05 |
Ping Gao |
Stabilized oral pharmaceutical composition
|
US6673818B2
(en)
|
2001-04-20 |
2004-01-06 |
Pharmacia Corporation |
Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation
|
WO2002088124A2
(en)
|
2001-04-27 |
2002-11-07 |
Smithkline Beecham Corporation |
Pyrazolo'1,5-a!pyridine derivatives
|
US6756498B2
(en)
|
2001-04-27 |
2004-06-29 |
Smithkline Beecham Corporation |
Process for the preparation of chemical compounds
|
UA81224C2
(en)
|
2001-05-02 |
2007-12-25 |
Euro Celtic S A |
Dosage form of oxycodone and use thereof
|
US20040132780A1
(en)
*
|
2001-05-04 |
2004-07-08 |
Allen Christopher P. |
Method and compositions for treating migraines
|
ATE493130T1
(en)
|
2001-05-11 |
2011-01-15 |
Endo Pharmaceuticals Inc |
MEDICINAL FORM CONTAINING OPIOID AGAINST ABUSE
|
GB0112810D0
(en)
*
|
2001-05-25 |
2001-07-18 |
Glaxo Group Ltd |
Pyrimidine derivatives
|
GB0112802D0
(en)
*
|
2001-05-25 |
2001-07-18 |
Glaxo Group Ltd |
Pyrimidine derivatives
|
US20030153801A1
(en)
*
|
2001-05-29 |
2003-08-14 |
Pharmacia Corporation |
Compositions of cyclooxygenase-2 selective inhibitors and radiation for inhibition or prevention of cardiovascular disease
|
CN1547474A
(en)
*
|
2001-05-31 |
2004-11-17 |
|
Skin-permeable selective cyclooxygenase-2 inhibitor composition
|
DE10129320A1
(en)
*
|
2001-06-19 |
2003-04-10 |
Norbert Mueller |
Use of cyclooxygenase-2 inhibitor in the preparation of a medicament for treating psychiatric disorders e.g. schizophrenia
|
US20060167074A1
(en)
*
|
2001-06-19 |
2006-07-27 |
Norbert Muller |
Methods and compositions for the treatment of psychiatric disorders
|
KR20040018281A
(en)
|
2001-06-21 |
2004-03-02 |
스미스클라인 비참 코포레이션 |
Imidazo‘1,2-α!pyridine derivatives for the prophylaxis and treatment of herpes viral infections
|
EP1273582B1
(en)
|
2001-07-05 |
2005-06-29 |
Pfizer Products Inc. |
Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents
|
DE60230632D1
(en)
|
2001-07-18 |
2009-02-12 |
Euro Celtique Sa |
PHARMACEUTICAL COMBINATIONS OF OXYCODONE AND NALOXONE
|
US20030044458A1
(en)
|
2001-08-06 |
2003-03-06 |
Curtis Wright |
Oral dosage form comprising a therapeutic agent and an adverse-effect agent
|
UA80682C2
(en)
*
|
2001-08-06 |
2007-10-25 |
Pharmacia Corp |
Orally deliverable stabilized oral suspension formulation and process for the incresaing physical stability of thixotropic pharmaceutical composition
|
WO2003013433A2
(en)
|
2001-08-06 |
2003-02-20 |
Euro-Celtique S.A. |
Sequestered antagonist formulations
|
ATE431738T1
(en)
|
2001-08-06 |
2009-06-15 |
Euro Celtique Sa |
OPIOID AGONIST FORMULATIONS WITH RELEASABLE AND SEQUESTRED ANTAGONIST
|
US20030068375A1
(en)
|
2001-08-06 |
2003-04-10 |
Curtis Wright |
Pharmaceutical formulation containing gelling agent
|
GB0119477D0
(en)
*
|
2001-08-09 |
2001-10-03 |
Glaxo Group Ltd |
Pyrimidine derivatives
|
AR038957A1
(en)
|
2001-08-15 |
2005-02-02 |
Pharmacia Corp |
COMBINATION THERAPY FOR CANCER TREATMENT
|
WO2003018575A1
(en)
*
|
2001-08-24 |
2003-03-06 |
Wyeth Holdings Corporation |
5-substituted-3(2h)-furanones useful for inhibition of farnesyl-protein transferase
|
US20030236308A1
(en)
*
|
2001-09-18 |
2003-12-25 |
Pharmacia Corporation |
Compositions of cyclooxygenase-2 selective inhibitors and acetaminophen for treatment and prevention of inflammation, inflammation-mediated disorders and pain
|
US20030114483A1
(en)
*
|
2001-09-18 |
2003-06-19 |
Pharmacia Corporation |
Compositions of chromene cyclooxygenase-2 selective inhibitors and acetaminophen for treatment and prevention of inflammation, inflammation-mediated disorders and pain
|
KR20040058189A
(en)
*
|
2001-09-26 |
2004-07-03 |
파마시아 코포레이션 |
Organoleptically acceptable intraorally disintegrating compositions
|
GT200200183A
(en)
|
2001-09-28 |
2003-05-23 |
|
PROCEDURE TO PREPARE DERIVATIVES OF HETEROCICLOALQUILSULFONIL PIRAZOL
|
WO2003031446A1
(en)
|
2001-10-05 |
2003-04-17 |
Smithkline Beecham Corporation |
Imidazo-pyridine derivatives for use in the treatment of herpes viral infection
|
KR100810468B1
(en)
|
2001-10-10 |
2008-03-07 |
씨제이제일제당 (주) |
1H-indole derivatives as a highly selective cyclooxygenase-2 inhibitor
|
KR100824233B1
(en)
|
2001-10-10 |
2008-04-24 |
씨제이제일제당 (주) |
3,4-Dihydro-1H-naphthalene derivatives as a highly selective cyclooxygenase-2 inhibitor
|
WO2003037336A1
(en)
|
2001-11-02 |
2003-05-08 |
Pfizer Products Inc. |
1-(5-sulfonyl-pyridin-2-yl)-5-(methylidene-cycloalkylmethoxy)-1h-pyrazole-4-carbonitrile derivatives and other compounds as cyclooxygenase inhibitors for the treatment of arthritis, neurodegeneration and colon cancer
|
DE60231439D1
(en)
|
2001-12-06 |
2009-04-16 |
Merck & Co Inc |
MITOTIC KINESINE HEMMER
|
FR2833164B1
(en)
*
|
2001-12-07 |
2004-07-16 |
Oreal |
ANTISOLAR COSMETIC COMPOSITIONS BASED ON A SYNERGISTIC MIXTURE OF FILTERS AND USES
|
JP2005516916A
(en)
|
2001-12-11 |
2005-06-09 |
スミスクライン ビーチャム コーポレーション |
Pyrazolo-pyridine derivatives as anti-herpes drugs
|
DE10162120A1
(en)
*
|
2001-12-12 |
2003-06-18 |
Berolina Drug Dev Ab Svedala |
Deuterated substituted dihydrofuranones and medicaments containing these compounds
|
US20040082940A1
(en)
*
|
2002-10-22 |
2004-04-29 |
Michael Black |
Dermatological apparatus and method
|
US20030212138A1
(en)
*
|
2002-01-14 |
2003-11-13 |
Pharmacia Corporation |
Combinations of peroxisome proliferator-activated receptor-alpha agonists and cyclooxygenase-2 selective inhibitors and therapeutic uses therefor
|
US20030220374A1
(en)
*
|
2002-01-14 |
2003-11-27 |
Pharmacia Corporation |
Compositions and methods of treatment involving peroxisome proliferator-activated receptor-gamma agonists and cyclooxygenase-2 selective inhibitors
|
US7985771B2
(en)
*
|
2002-01-31 |
2011-07-26 |
Monsanto Technology Llc |
Furanone derivatives
|
US6667330B2
(en)
|
2002-01-31 |
2003-12-23 |
Galileo Pharmaceuticals, Inc. |
Furanone derivatives
|
EP2243471A1
(en)
|
2002-04-05 |
2010-10-27 |
Euro-Celtique S.A. |
Matrix for sustained, invariant and independent release of active compounds
|
CA2481035A1
(en)
*
|
2002-04-08 |
2003-10-16 |
Glaxo Group Limited |
(2-((2-alkoxy) -phenyl) -cyclopent-1-enyl) aromatic carbo and heterocyclic acid and derivatives
|
IL164163A0
(en)
*
|
2002-04-09 |
2005-12-18 |
Pharmacia Corp |
Process for preparing a finely self-emulsifiable pharmaceutical composition
|
US7329401B2
(en)
|
2002-04-15 |
2008-02-12 |
The Regents Of The University Of California |
Cyclooxygenase-2 selective agents useful as imaging probes and related methods
|
JP2005532792A
(en)
|
2002-04-17 |
2005-11-04 |
ザ クリーブランド クリニック ファウンデーション |
Systemic markers for monitoring anti-inflammatory and antioxidant effects of therapeutic agents
|
CA2484017A1
(en)
*
|
2002-04-22 |
2003-10-30 |
Pfizer Products Inc. |
Indol-2-ones as selective inhibitors of cyclooxygenase-2
|
GB0210121D0
(en)
|
2002-05-02 |
2002-06-12 |
Celltech R&D Ltd |
Biological products
|
US7670769B2
(en)
|
2002-05-09 |
2010-03-02 |
The Brigham And Women's Hospital, Inc. |
IL1RL-1 as a cardiovascular disease marker and therapeutic target
|
WO2003095623A2
(en)
*
|
2002-05-10 |
2003-11-20 |
The Trustees Of Columbia University In The City Of New York |
Genetically engineered cell lines and systems for propagating varicella zoster virus and methods of use thereof
|
KR100804827B1
(en)
*
|
2002-05-17 |
2008-02-20 |
씨제이제일제당 (주) |
Thiazolidine derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same
|
US20030225054A1
(en)
*
|
2002-06-03 |
2003-12-04 |
Jingwu Duan |
Combined use of tace inhibitors and COX2 inhibitors as anti-inflammatory agents
|
KR100478467B1
(en)
|
2002-06-24 |
2005-03-23 |
씨제이 주식회사 |
Pyrazol-3-one derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same
|
KR100465455B1
(en)
|
2002-06-24 |
2005-01-13 |
씨제이 주식회사 |
Thioxo thiazole derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same
|
US7087630B2
(en)
*
|
2002-06-27 |
2006-08-08 |
Nitromed, Inc. |
Cyclooxygenase 2 selective inhibitors, compositions and methods of use
|
JP2005535642A
(en)
*
|
2002-06-28 |
2005-11-24 |
ニトロメッド インコーポレーティッド |
Nitrosated and / or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use containing oximes and / or hydrazones
|
WO2004004833A1
(en)
*
|
2002-07-02 |
2004-01-15 |
Pharmacia Corporation |
Use of cyclooxygenase-2 selective inhibitors and thrombolytic agents for the treatment or prevention of a vaso-occlusive event
|
KR100467668B1
(en)
|
2002-08-07 |
2005-01-24 |
씨제이 주식회사 |
1,2,4-Triazole derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same
|
US7235560B2
(en)
*
|
2002-08-19 |
2007-06-26 |
Glaxo Group Limited |
Pyrimidine derivative as selective COX-2 inhibitors
|
DE10238045A1
(en)
|
2002-08-20 |
2004-03-04 |
Merckle Gmbh Chem.-Pharm. Fabrik |
2-Thio-substituted imidazole derivatives and their use in pharmacy
|
UY27939A1
(en)
|
2002-08-21 |
2004-03-31 |
Glaxo Group Ltd |
COMPOUNDS
|
GB0221443D0
(en)
|
2002-09-16 |
2002-10-23 |
Glaxo Group Ltd |
Pyridine derivates
|
DK1551372T3
(en)
|
2002-09-20 |
2018-07-23 |
Alpharma Pharmaceuticals Llc |
SEQUERATION SUBSTANCES AND RELATED COMPOSITIONS AND PROCEDURES
|
US8303511B2
(en)
*
|
2002-09-26 |
2012-11-06 |
Pacesetter, Inc. |
Implantable pressure transducer system optimized for reduced thrombosis effect
|
JP2006504728A
(en)
|
2002-10-03 |
2006-02-09 |
スミスクライン ビーチャム コーポレーション |
Pyrazolopyridine derivative therapeutic compounds
|
US7255860B2
(en)
|
2002-10-08 |
2007-08-14 |
Rinat Neuroscience Corp. |
Methods for treating post-surgical pain by administering an anti-nerve growth factor antagonist antibody
|
ES2357948T3
(en)
*
|
2002-10-08 |
2011-05-04 |
Rinat Neuroscience Corp. |
PROCEDURES TO TREAT POST-SURGICAL PAIN THROUGH THE ADMINISTRATION OF AN ANTIBODY AGAINST THE NERVOUS GROWTH FACTOR AND COMPOSITIONS CONTAINING THE SAME.
|
KR100484525B1
(en)
*
|
2002-10-15 |
2005-04-20 |
씨제이 주식회사 |
Isothiazole derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same
|
US20040082543A1
(en)
*
|
2002-10-29 |
2004-04-29 |
Pharmacia Corporation |
Compositions of cyclooxygenase-2 selective inhibitors and NMDA receptor antagonists for the treatment or prevention of neuropathic pain
|
US7399764B2
(en)
*
|
2002-10-30 |
2008-07-15 |
Merck & Co., Inc. |
Inhibitors of Akt activity
|
GB0225548D0
(en)
*
|
2002-11-01 |
2002-12-11 |
Glaxo Group Ltd |
Compounds
|
AU2003283096A1
(en)
*
|
2002-11-05 |
2004-06-07 |
Merck Frosst Canada And Co. |
Nitric oxide releasing prodrugs of diaryl-2-(5h)-furanones as cyclooxygenase-2 inhibitors
|
WO2004043358A2
(en)
*
|
2002-11-08 |
2004-05-27 |
Bristol-Myers Squibb Company |
Formulations of low solubility bioactive agents and processes for making the same
|
US20040147581A1
(en)
*
|
2002-11-18 |
2004-07-29 |
Pharmacia Corporation |
Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy
|
KR100470075B1
(en)
|
2002-11-21 |
2005-02-05 |
씨제이 주식회사 |
1,2,4-triazole derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same
|
GB0227443D0
(en)
*
|
2002-11-25 |
2002-12-31 |
Glaxo Group Ltd |
Pyrimidine derivatives
|
KR100491317B1
(en)
|
2002-11-26 |
2005-05-24 |
씨제이 주식회사 |
1,2,4-Triazole derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same
|
KR100470076B1
(en)
|
2002-11-27 |
2005-02-05 |
씨제이 주식회사 |
1,2,4-triazole derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same
|
KR20050085563A
(en)
|
2002-12-13 |
2005-08-29 |
워너-램버트 캄파니 엘엘씨 |
Alpha-2-delta ligand to treat lower urinary tract symptoms
|
PL377427A1
(en)
*
|
2002-12-19 |
2006-02-06 |
Pharmacia Corporation |
Methods and compositions for the treatment of herpes virus infections using cyclooxygenase-2 selective inhibitors or cyclooxygenase-2 inhibitors in combination with antiviral agents
|
WO2004058354A1
(en)
*
|
2002-12-20 |
2004-07-15 |
Pharmacia Corporation |
Compositions of cyclooxygenase-2 selective inhibitors and selective serotonin reuptake inhibitors for the treatment or prevention of a vaso-occlusive event
|
ES2215474B1
(en)
*
|
2002-12-24 |
2005-12-16 |
J. URIACH & CIA S.A. |
NEW DERIVATIVES OF PHOSPHORAMIDE.
|
US7569364B2
(en)
*
|
2002-12-24 |
2009-08-04 |
Pfizer Inc. |
Anti-NGF antibodies and methods using same
|
PT1575517E
(en)
|
2002-12-24 |
2012-05-28 |
Rinat Neuroscience Corp |
Anti-ngf antibodies and methods using same
|
US9498530B2
(en)
|
2002-12-24 |
2016-11-22 |
Rinat Neuroscience Corp. |
Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same
|
AU2003303631B2
(en)
*
|
2002-12-26 |
2008-05-29 |
Nuvo Pharmaceuticals (Ireland) Designated Activity Company |
Multilayer Dosage Forms Containing NSAIDs and Triptans
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
US20070265606A1
(en)
*
|
2003-02-14 |
2007-11-15 |
Reliant Technologies, Inc. |
Method and Apparatus for Fractional Light-based Treatment of Obstructive Sleep Apnea
|
PL379983A1
(en)
|
2003-02-19 |
2006-11-27 |
Rinat Neuroscience Corp. |
Methods for treating pain by administering a nerve growth factor antagonist and an nsaid and compositions containing the same
|
US20050004098A1
(en)
*
|
2003-03-20 |
2005-01-06 |
Britten Nancy Jean |
Dispersible formulation of an anti-inflammatory agent
|
RU2325189C2
(en)
*
|
2003-03-20 |
2008-05-27 |
Фармация Корпорейшн |
Method and pharmaceutical composition for antiphlogistic agent delivery
|
US20050009931A1
(en)
*
|
2003-03-20 |
2005-01-13 |
Britten Nancy Jean |
Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
|
US20040214753A1
(en)
*
|
2003-03-20 |
2004-10-28 |
Britten Nancy Jean |
Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
|
US20040220155A1
(en)
*
|
2003-03-28 |
2004-11-04 |
Pharmacia Corporation |
Method of providing a steroid-sparing benefit with a cyclooxygenase-2 inhibitor and compositions therewith
|
TWI347201B
(en)
|
2003-04-21 |
2011-08-21 |
Euro Celtique Sa |
Pharmaceutical products,uses thereof and methods for preparing the same
|
WO2004093814A2
(en)
*
|
2003-04-22 |
2004-11-04 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a sodium channel blocker
|
WO2004093813A2
(en)
*
|
2003-04-22 |
2004-11-04 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a calcium modulating agent for the treatment of pain, inflammation or inflammation mediated disorders
|
WO2004093816A2
(en)
*
|
2003-04-22 |
2004-11-04 |
Pharmacia Corporation |
Compositions comprising a selective cox-2 inhibitor and a calcium modulating agent
|
WO2004093895A1
(en)
*
|
2003-04-22 |
2004-11-04 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a potassium ion channel modulator for the treatment of pain, inflammation or inflammation mediated disorders
|
US20050107387A1
(en)
*
|
2003-05-13 |
2005-05-19 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a peroxisome proliferator activated receptor agonist for the treatment of ischemic mediated central nervous system disorders
|
US20060160776A1
(en)
*
|
2003-05-28 |
2006-07-20 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a cannabinoid agent for the treatment of central nervous system damage
|
AP2501A
(en)
|
2003-05-30 |
2012-10-22 |
Ranbaxy Lab Ltd |
Substituted pyrrole derivatives
|
CN1309717C
(en)
*
|
2003-06-03 |
2007-04-11 |
李小虎 |
4-aryl group-5H-thoifuran-2-ketone derivative, producing method and use thereof
|
CA2527368A1
(en)
*
|
2003-06-06 |
2004-12-23 |
Glaxo Group Limited |
Pharmaceutical composition
|
WO2005000238A2
(en)
*
|
2003-06-20 |
2005-01-06 |
Merck & Co., Inc. |
Use of selective cyclooxygenase-2 inhibitors for the treatment of endometriosis
|
MXPA05013624A
(en)
*
|
2003-06-24 |
2006-02-24 |
Pharmacia Corp |
Treatment of migraine accompanied by nausea.
|
WO2005007106A2
(en)
*
|
2003-07-10 |
2005-01-27 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a non-nmda glutamate modulator for the treatment of central nervous system damage
|
WO2005009342A2
(en)
*
|
2003-07-16 |
2005-02-03 |
Pharmacia Corporation |
Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith
|
US20050075341A1
(en)
*
|
2003-07-17 |
2005-04-07 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and an IKK inhibitor for the treatment of ischemic mediated central nervous system disorders or injury
|
WO2005018561A2
(en)
*
|
2003-08-20 |
2005-03-03 |
Nitromed, Inc. |
Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use
|
US20050119262A1
(en)
*
|
2003-08-21 |
2005-06-02 |
Pharmacia Corporation |
Method for preventing or treating an optic neuropathy with a cox-2 inhibitor and an intraocular pressure reducing agent
|
US20050107350A1
(en)
*
|
2003-08-22 |
2005-05-19 |
Pharmacia Corporation |
Method for the treatment or prevention of bone disorders with a cyclooxygenase-2 inhibitor alone and in combination with a bone disorder treatment agent and compositions therewith
|
US20050187278A1
(en)
*
|
2003-08-28 |
2005-08-25 |
Pharmacia Corporation |
Treatment or prevention of vascular disorders with Cox-2 inhibitors in combination with cyclic AMP-specific phosphodiesterase inhibitors
|
EP1668008A4
(en)
*
|
2003-08-28 |
2009-02-25 |
Nitromed Inc |
Nitrosated ad nitrosylated diuretic compouds, compositions and methods of use
|
WO2005077344A2
(en)
|
2003-08-29 |
2005-08-25 |
The Brigham And Women's Hospital, Inc. |
Hydantoin derivatives as inhibitors of cellular necrosis
|
WO2005023189A2
(en)
*
|
2003-09-03 |
2005-03-17 |
Pharmacia Corporation |
Method of cox-2 selective inhibitor and nitric oxide-donating agent
|
US20050131028A1
(en)
*
|
2003-09-11 |
2005-06-16 |
Pharmacia Corporation |
Methods and compositions for the extended duration treatment of pain, inflammation and inflammation-related disorders
|
EP2298303A1
(en)
|
2003-09-25 |
2011-03-23 |
Euro-Celtique S.A. |
Pharmaceutical combinations of hydrocodone and naltrexone
|
GB0323584D0
(en)
*
|
2003-10-08 |
2003-11-12 |
Glaxo Group Ltd |
Compounds
|
GB0323581D0
(en)
*
|
2003-10-08 |
2003-11-12 |
Glaxo Group Ltd |
Novel compounds
|
GB0323585D0
(en)
*
|
2003-10-08 |
2003-11-12 |
Glaxo Group Ltd |
Compounds
|
FR2860792B1
(en)
*
|
2003-10-10 |
2006-02-24 |
Sanofi Synthelabo |
THIOPHENE-2-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE
|
WO2005044227A1
(en)
*
|
2003-11-05 |
2005-05-19 |
Glenmark Pharmaceuticals Limited |
Topical pharmaceutical compositions
|
US20050100594A1
(en)
*
|
2003-11-12 |
2005-05-12 |
Nilendu Sen |
Pharmaceutical formulation containing muscle relaxant and COX-II inhibitor
|
WO2005051919A1
(en)
*
|
2003-11-26 |
2005-06-09 |
Pfizer Products Inc. |
Aminopyrazole derivatives as gsk-3 inhibitors
|
US7070816B2
(en)
*
|
2003-12-05 |
2006-07-04 |
New Chapter, Inc. |
Methods for treating prostatic intraepithelial neoplasia with herbal compositions
|
US7781219B2
(en)
|
2003-12-05 |
2010-08-24 |
The Cleveland Clinic Foundation |
Risk markers for cardiovascular disease
|
US7067159B2
(en)
*
|
2003-12-05 |
2006-06-27 |
New Chapter, Inc. |
Methods for treating prostate cancer with herbal compositions
|
AU2005207037A1
(en)
*
|
2004-01-22 |
2005-08-04 |
Nitromed, Inc. |
Nitrosated and/or nitrosylated compounds, compositions and methods of use
|
US7449462B2
(en)
|
2004-01-22 |
2008-11-11 |
Pfizer, Inc. |
Triazole derivatives which inhibit vasopressin antagonistic activity
|
TW200602337A
(en)
*
|
2004-02-25 |
2006-01-16 |
Wyeth Corp |
Inhibitors of protein tyrosine phosphatase 1B
|
WO2005081960A2
(en)
*
|
2004-02-25 |
2005-09-09 |
Wyeth |
Inhibitors of protein tyrosine phosphatase 1b
|
DK2206728T3
(en)
|
2004-04-07 |
2018-04-23 |
Rinat Neuroscience Corp |
METHODS OF TREATING BONE CANCER PAIN BY SUBMITTING A NERVOUS FACTOR-ANTAGONISTIC ANTIBODY
|
WO2005105779A1
(en)
*
|
2004-04-28 |
2005-11-10 |
Pfizer Limited |
3-heterocyclyl-4-phenyl-triazole derivatives as inhibitors of the vasopressin v1a receptor
|
US7507823B2
(en)
*
|
2004-05-06 |
2009-03-24 |
Bristol-Myers Squibb Company |
Process of making aripiprazole particles
|
GB0410121D0
(en)
*
|
2004-05-06 |
2004-06-09 |
Glaxo Group Ltd |
Compounds
|
WO2005120584A2
(en)
*
|
2004-06-03 |
2005-12-22 |
The Trustees Of Columbia University In The City Of New York |
Radiolabeled arylsulfonyl compounds and uses thereof
|
EP1604666A1
(en)
|
2004-06-08 |
2005-12-14 |
Euro-Celtique S.A. |
Opioids for the treatment of the Chronic Obstructive Pulmonary Disease (COPD)
|
ES2653568T3
(en)
|
2004-06-12 |
2018-02-07 |
Collegium Pharmaceutical, Inc. |
Drug formulations for abuse prevention
|
US7632833B2
(en)
|
2004-07-01 |
2009-12-15 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
ES2257929B1
(en)
*
|
2004-07-16 |
2007-05-01 |
Laboratorios Del Dr. Esteve, S.A. |
DERIVATIVES OF PIRAZOLINA, PROCEDURE FOR OBTAINING AND USING THE SAME AS THERAPEUTIC AGENTS.
|
RU2007101510A
(en)
*
|
2004-07-22 |
2008-08-27 |
Фармаци Корпорейшн (US) |
COMPOSITIONS FOR TREATING INFLAMMATION AND PAIN USING THE COMBINATION OF THE COX-2 SELECTIVE INHIBITOR AND THE LTB4 RECEPTOR ANTAGONIST
|
EP2494992A1
(en)
|
2004-08-24 |
2012-09-05 |
Merck Sharp & Dohme Corp. |
Combination therapy for treating cyclooxygenase-2 mediated diseases or conditions in patients at risk of thrombotic cardiovascular events
|
US7622142B2
(en)
*
|
2004-09-14 |
2009-11-24 |
New Chapter Inc. |
Methods for treating glioblastoma with herbal compositions
|
US8271093B2
(en)
*
|
2004-09-17 |
2012-09-18 |
Cardiac Pacemakers, Inc. |
Systems and methods for deriving relative physiologic measurements using a backend computing system
|
WO2006041855A2
(en)
|
2004-10-04 |
2006-04-20 |
Nitromed, Inc. |
Compositions and methods using apocynin compounds and nitric oxide donors
|
EP2343553A1
(en)
|
2004-10-06 |
2011-07-13 |
The Brigham and Women's Hospital |
Relevance of achieved levels of markers of systemic inflammation following treatment
|
WO2006052899A2
(en)
*
|
2004-11-08 |
2006-05-18 |
Nitromed, Inc. |
Nitrosated and nitrosylated compounds, compositions and methods for the treatment of ophthalmic disorders
|
US20080275093A1
(en)
*
|
2004-11-15 |
2008-11-06 |
Nitromed, Inc. |
Diuretic Compounds Comprising Heterocyclic Nitric Oxide Donor Groups, Compositions and Methods of Use
|
US20100137378A1
(en)
|
2004-12-23 |
2010-06-03 |
Glaxo Group Limited |
Pyridine Compounds For The Treatment Of Prostaglandin Mediated Diseases
|
NZ555693A
(en)
|
2004-12-27 |
2010-10-29 |
Eisai R&D Man Co Ltd |
Matrix type sustained-release preparation containing donepezil
|
AU2006206249A1
(en)
*
|
2005-01-21 |
2006-07-27 |
Nicox S.A. |
Cardiovascular compounds comprising heterocyclic nitric oxide donor group compositions and methods of use
|
SG175477A1
(en)
*
|
2005-01-31 |
2011-11-28 |
Mylan Lab Inc |
Hydroxylated nebivolol metabolites
|
CA2597422A1
(en)
*
|
2005-02-16 |
2007-08-02 |
Nitromed, Inc. |
Organic nitric oxide donor salts of antimicrobial compounds, compositions and methods of use
|
US7521435B2
(en)
*
|
2005-02-18 |
2009-04-21 |
Pharma Diagnostics, N.V. |
Silicon containing compounds having selective COX-2 inhibitory activity and methods of making and using the same
|
EP1702558A1
(en)
|
2005-02-28 |
2006-09-20 |
Euro-Celtique S.A. |
Method and device for the assessment of bowel function
|
EP1858863A1
(en)
*
|
2005-02-28 |
2007-11-28 |
Nitromed, Inc. |
Cardiovascular compounds comprising nitric oxide enhancing groups, compositions and methods of use
|
WO2006099058A2
(en)
*
|
2005-03-09 |
2006-09-21 |
Nitromed, Inc. |
Organic nitric oxide enhancing salts of angiotensin ii antagonists, compositions and methods of use
|
WO2006110918A1
(en)
*
|
2005-04-13 |
2006-10-19 |
Ambit Biosciences Corporation |
Pyrrole compounds and uses thereof
|
CA2604617C
(en)
*
|
2005-04-28 |
2014-06-17 |
Eisai R&D Management Co., Ltd. |
Composition containing anti-dementia drug
|
CA2607913C
(en)
*
|
2005-05-05 |
2014-03-18 |
Cook Biotech Incorporated |
Implantable materials and methods for inhibiting tissue adhesion formation
|
ES2382814T3
(en)
|
2005-05-17 |
2012-06-13 |
Merck Sharp & Dohme Ltd. |
Cis-4 - [(4-chlorophenyl) sulfonyl] -4- (2,5-difluorophenyl) cyclohexanopropanoic acid for cancer treatment
|
EP1885713A1
(en)
*
|
2005-05-18 |
2008-02-13 |
Pfizer Limited |
1, 2, 4 -triazole derivatives as vasopressin antagonists
|
EP1883614A4
(en)
*
|
2005-05-23 |
2010-04-14 |
Nicox Sa |
Organic nitric oxide enhancing salts of nonsteroidal antiinflammatory compounds, compositions and methods of use
|
AU2005332300B2
(en)
|
2005-05-31 |
2011-07-07 |
Mylan Laboratories, Inc. |
Compositions comprising nebivolol
|
EP1915157A4
(en)
*
|
2005-08-02 |
2010-09-01 |
Nicox Sa |
Nitric oxide enhancing antimicrobial compounds, compositions and methods of use
|
TW200804345A
(en)
|
2005-08-30 |
2008-01-16 |
Novartis Ag |
Substituted benzimidazoles and methods of preparation
|
CA2624933A1
(en)
*
|
2005-10-04 |
2007-04-12 |
Nitromed, Inc. |
Methods for treating respiratory disorders
|
US8119358B2
(en)
|
2005-10-11 |
2012-02-21 |
Tethys Bioscience, Inc. |
Diabetes-related biomarkers and methods of use thereof
|
EP1948599A1
(en)
|
2005-11-08 |
2008-07-30 |
Ranbaxy Laboratories Limited |
Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
|
EP1954685A4
(en)
*
|
2005-11-16 |
2009-11-11 |
Nitromed Inc |
Furoxan compounds, compositions and methods of use
|
TW200735866A
(en)
|
2005-11-18 |
2007-10-01 |
Synta Pharmaceuticals Corp |
Compounds for the treatment of proliferative disorders
|
EP1968584A2
(en)
*
|
2005-12-20 |
2008-09-17 |
Nitromed, Inc. |
Nitric oxide enhancing glutamic acid compounds, compositions and methods of use
|
EP1971340A2
(en)
*
|
2005-12-22 |
2008-09-24 |
Nitromed, Inc. |
Nitric oxide enhancing pyruvate compounds, compositions and methods of use
|
WO2007087246A2
(en)
|
2006-01-24 |
2007-08-02 |
Merck & Co., Inc. |
Jak2 tyrosine kinase inhibition
|
GB0603041D0
(en)
|
2006-02-15 |
2006-03-29 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
EP2001496B1
(en)
|
2006-03-15 |
2017-05-31 |
The Brigham And Women's Hospital, Inc. |
Use of gelsolin to diagnose and treat inflammatory diseases
|
US8067414B2
(en)
|
2006-03-29 |
2011-11-29 |
Nicox S.A. |
Nitric oxide enhancing prostaglandin compounds, compositions and methods of use
|
LT2010528T
(en)
|
2006-04-19 |
2017-12-27 |
Novartis Ag |
6-o-substituted benzoxazole and benzothiazole compounds and methods of inhibiting csf-1r signaling
|
EP2302395B1
(en)
|
2006-06-07 |
2015-04-15 |
Health Diagnostic Laboratory, Inc. |
Markers associated with arteriovascular events and methods of use thereof
|
CN101677963B
(en)
|
2006-06-19 |
2012-05-30 |
奥尔制药公司 |
Pharmaceutical compositions
|
US8128460B2
(en)
*
|
2006-09-14 |
2012-03-06 |
The Material Works, Ltd. |
Method of producing rust inhibitive sheet metal through scale removal with a slurry blasting descaling cell
|
CA2664113C
(en)
|
2006-09-22 |
2013-05-28 |
Merck & Co., Inc. |
Use of platencin and platensimycin as fatty acid synthesis inhibitors to treat obesity, diabetes and cancer
|
US20080208179A1
(en)
*
|
2006-10-26 |
2008-08-28 |
Reliant Technologies, Inc. |
Methods of increasing skin permeability by treatment with electromagnetic radiation
|
AU2007313630B2
(en)
*
|
2006-10-31 |
2013-07-04 |
Bio-Tec Environmental, Llc |
Chemical additives to make polymeric materials biodegradable
|
US8513329B2
(en)
|
2006-10-31 |
2013-08-20 |
Bio-Tec Environmental, Llc |
Chemical additives to make polymeric materials biodegradable
|
US20110218176A1
(en)
|
2006-11-01 |
2011-09-08 |
Barbara Brooke Jennings-Spring |
Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
|
JP5308350B2
(en)
|
2006-12-22 |
2013-10-09 |
レコルダーティ アイルランド リミテッド |
Combination therapy of lower urinary tract dysfunction using α2δ ligand and NSAID
|
BRPI0806245B1
(en)
|
2007-01-10 |
2022-01-25 |
Msd Italia S.R.L. |
Compounds of formula i and their uses
|
US20100111858A1
(en)
*
|
2007-01-19 |
2010-05-06 |
Howard Carol P |
Diangostic and Therapeutic Cyclooxygenase-2 Binding Ligands
|
BRPI0808523A2
(en)
|
2007-03-01 |
2014-08-19 |
Novartis Vaccines & Diagnostic |
PIM KINASE INHIBITORS AND METHODS OF USE
|
GB0704407D0
(en)
|
2007-03-07 |
2007-04-18 |
Glaxo Group Ltd |
Compounds
|
DK2147315T3
(en)
|
2007-04-18 |
2013-09-23 |
Tethys Bioscience Inc |
DIABETES-RELATED BIOMARKETS AND METHODS FOR USE THEREOF
|
CA2685967A1
(en)
|
2007-05-21 |
2008-11-21 |
Novartis Ag |
Csf-1r inhibitors, compositions, and methods of use
|
EP2170076B1
(en)
|
2007-06-27 |
2016-05-18 |
Merck Sharp & Dohme Corp. |
4-carboxybenzylamino derivatives as histone deacetylase inhibitors
|
CN101801188A
(en)
|
2007-07-12 |
2010-08-11 |
特拉加拉医药品公司 |
Methods and compositions for the treatment of cancer, tumors, and tumor-related disorders
|
US7943658B2
(en)
*
|
2007-07-23 |
2011-05-17 |
Bristol-Myers Squibb Company |
Indole indane amide compounds useful as CB2 agonists and method
|
CA2699157A1
(en)
|
2007-09-10 |
2009-03-19 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
US8623418B2
(en)
|
2007-12-17 |
2014-01-07 |
Alpharma Pharmaceuticals Llc |
Pharmaceutical composition
|
US8598184B2
(en)
|
2008-03-03 |
2013-12-03 |
Tiger Pharmatech |
Protein kinase inhibitors
|
GB2462022B
(en)
|
2008-06-16 |
2011-05-25 |
Biovascular Inc |
Controlled release compositions of agents that reduce circulating levels of platelets and methods thereof
|
GB0813142D0
(en)
|
2008-07-17 |
2008-08-27 |
Glaxo Group Ltd |
Novel compounds
|
GB0813144D0
(en)
|
2008-07-17 |
2008-08-27 |
Glaxo Group Ltd |
Novel compounds
|
MX2011002149A
(en)
|
2008-08-27 |
2011-04-05 |
Calcimedica Inc |
Compounds that modulate intracellular calcium.
|
EP2177215A1
(en)
|
2008-10-17 |
2010-04-21 |
Laboratorios Del. Dr. Esteve, S.A. |
Co-crystals of tramadol and NSAIDs
|
CN101429181A
(en)
*
|
2008-12-18 |
2009-05-13 |
毛近隆 |
P-hydroxybenzene acrylic acid derivative and uses thereof
|
WO2010071865A1
(en)
|
2008-12-19 |
2010-06-24 |
Nuon Therapeutics, Inc. |
Pharmaceutical compositions and methods for treating hyperuricemia and related disorders
|
US20100160351A1
(en)
*
|
2008-12-19 |
2010-06-24 |
Nuon Therapeutics, Inc. |
Pharmaceutical compositions and methods for treating hyperuricemia and related disorders
|
GB0903493D0
(en)
|
2009-02-27 |
2009-04-08 |
Vantia Ltd |
New compounds
|
DK2405915T3
(en)
|
2009-03-10 |
2019-02-11 |
Euro Celtique Sa |
PHARMACEUTICAL COMPOSITIONS WITH IMMEDIATE RELEASE INCLUDING OXYCODON AND NALOXON
|
WO2011012622A1
(en)
|
2009-07-30 |
2011-02-03 |
Glaxo Group Limited |
Benzoxazinone derivatives for the treatment of glytl mediated disorders
|
WO2011023753A1
(en)
|
2009-08-27 |
2011-03-03 |
Glaxo Group Limited |
Benzoxazine derivatives as glycine transport inhibitors
|
WO2011032175A1
(en)
|
2009-09-14 |
2011-03-17 |
Nuon Therapeutics, Inc. |
Combination formulations of tranilast and allopurinol and methods related thereto
|
WO2011046771A1
(en)
|
2009-10-14 |
2011-04-21 |
Schering Corporation |
SUBSTITUTED PIPERIDINES THAT INCREASE p53 ACTIVITY AND THE USES THEREOF
|
US10668060B2
(en)
|
2009-12-10 |
2020-06-02 |
Collegium Pharmaceutical, Inc. |
Tamper-resistant pharmaceutical compositions of opioids and other drugs
|
WO2011075478A1
(en)
|
2009-12-16 |
2011-06-23 |
N30 Pharmaceuticals, Llc |
Novel thiophene inhibitors of s-nitrosoglutathione reductase
|
GB201000685D0
(en)
|
2010-01-15 |
2010-03-03 |
Glaxo Group Ltd |
Novel compounds
|
TW201201764A
(en)
|
2010-02-01 |
2012-01-16 |
Hospital For Sick Children |
Remote ischemic conditioning for treatment and prevention of restenosis
|
WO2011121402A2
(en)
|
2010-03-31 |
2011-10-06 |
The Hospital For Sick Children |
Use of remote ischemic conditioning to improve outcome after myocardial infarction
|
WO2011139489A2
(en)
|
2010-04-27 |
2011-11-10 |
Calcimedica Inc. |
Compounds that modulate intracellular calcium
|
AU2011248579A1
(en)
|
2010-04-27 |
2012-11-29 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
GB201007789D0
(en)
|
2010-05-10 |
2010-06-23 |
Glaxo Group Ltd |
Novel Compound
|
GB201007791D0
(en)
|
2010-05-10 |
2010-06-23 |
Glaxo Group Ltd |
Novel compounds
|
WO2011163330A1
(en)
|
2010-06-24 |
2011-12-29 |
Merck Sharp & Dohme Corp. |
Novel heterocyclic compounds as erk inhibitors
|
ES2529233T3
(en)
|
2010-07-09 |
2015-02-18 |
Convergence Pharmaceuticals Limited |
Tetrazole compounds as calcium channel blockers
|
CA2805265A1
(en)
|
2010-08-02 |
2012-02-09 |
Merck Sharp & Dohme Corp. |
Rna interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (ctnnb1) gene expression using short interfering nucleic acid (sina)
|
WO2012024170A2
(en)
|
2010-08-17 |
2012-02-23 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF HEPATITIS B VIRUS (HBV) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
HUE058226T2
(en)
|
2010-08-19 |
2022-07-28 |
Zoetis Belgium S A |
Anti-ngf antibodies and their use
|
US8883801B2
(en)
|
2010-08-23 |
2014-11-11 |
Merck Sharp & Dohme Corp. |
Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors
|
US9079891B2
(en)
|
2010-08-27 |
2015-07-14 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
US8946216B2
(en)
|
2010-09-01 |
2015-02-03 |
Merck Sharp & Dohme Corp. |
Indazole derivatives useful as ERK inhibitors
|
EP2615916B1
(en)
|
2010-09-16 |
2017-01-04 |
Merck Sharp & Dohme Corp. |
Fused pyrazole derivatives as novel erk inhibitors
|
WO2012058210A1
(en)
|
2010-10-29 |
2012-05-03 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACIDS (siNA)
|
WO2012087772A1
(en)
|
2010-12-21 |
2012-06-28 |
Schering Corporation |
Indazole derivatives useful as erk inhibitors
|
CN103370058A
(en)
|
2010-12-22 |
2013-10-23 |
普渡制药公司 |
Encased tamper resistant controlled release dosage forms
|
CN107412173A
(en)
|
2010-12-23 |
2017-12-01 |
普渡制药公司 |
Anti-distort solid oral dosage form
|
EP2665729B1
(en)
|
2011-01-19 |
2015-04-01 |
Convergence Pharmaceuticals Limited |
Piperazine derivatives as cav2.2 calcium channel blockers
|
JP2014514321A
(en)
|
2011-04-21 |
2014-06-19 |
メルク・シャープ・アンド・ドーム・コーポレーション |
Insulin-like growth factor 1 receptor inhibitor
|
CN108373502B
(en)
|
2011-05-20 |
2022-03-22 |
H.伦德贝克公司 |
anti-CGRP compositions and uses thereof
|
US9023865B2
(en)
|
2011-10-27 |
2015-05-05 |
Merck Sharp & Dohme Corp. |
Compounds that are ERK inhibitors
|
WO2013066729A1
(en)
|
2011-10-31 |
2013-05-10 |
Merck Sharp & Dohme Corp. |
Aminopyrimidinones as interleukin receptor-associated kinase inhibitors
|
GB201122113D0
(en)
|
2011-12-22 |
2012-02-01 |
Convergence Pharmaceuticals |
Novel compounds
|
US20150299696A1
(en)
|
2012-05-02 |
2015-10-22 |
Sirna Therapeutics, Inc. |
SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS
|
WO2013170186A1
(en)
|
2012-05-11 |
2013-11-14 |
Reset Therapeutics, Inc. |
Carbazole-containing sulfonamides as cryptochrome modulators
|
EP2859018B1
(en)
|
2012-06-06 |
2021-09-22 |
Zoetis Services LLC |
Caninized anti-ngf antibodies and methods thereof
|
WO2014052563A2
(en)
|
2012-09-28 |
2014-04-03 |
Merck Sharp & Dohme Corp. |
Novel compounds that are erk inhibitors
|
US9512116B2
(en)
|
2012-10-12 |
2016-12-06 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
MX363243B
(en)
|
2012-11-28 |
2019-03-14 |
Merck Sharp & Dohme |
Compositions and methods for treating cancer.
|
RU2690663C2
(en)
|
2012-12-20 |
2019-06-05 |
Мерк Шарп И Доум Корп. |
Substituted imidazopyridines as hdm2 inhibitors
|
US9540377B2
(en)
|
2013-01-30 |
2017-01-10 |
Merck Sharp & Dohme Corp. |
2,6,7,8 substituted purines as HDM2 inhibitors
|
MX2015010041A
(en)
|
2013-02-05 |
2015-10-30 |
Purdue Pharma Lp |
Tamper resistant pharmaceutical formulations.
|
JP2016514693A
(en)
|
2013-03-15 |
2016-05-23 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
Hybrid necrotosis inhibitor
|
US10751287B2
(en)
|
2013-03-15 |
2020-08-25 |
Purdue Pharma L.P. |
Tamper resistant pharmaceutical formulations
|
TWI634114B
(en)
|
2013-05-08 |
2018-09-01 |
永恒生物科技公司 |
Furanone compounds as kinase inhibitors
|
EP3019171B1
(en)
|
2013-07-11 |
2018-09-05 |
Merck Sharp & Dohme Corp. |
Substituted amidopyrazole inhibitors of interleukin receptor-associated kinases (irak-4)
|
KR20180037074A
(en)
|
2013-07-23 |
2018-04-10 |
유로-셀티큐 에스.에이. |
A combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation
|
US20160194368A1
(en)
|
2013-09-03 |
2016-07-07 |
Moderna Therapeutics, Inc. |
Circular polynucleotides
|
WO2015054283A1
(en)
|
2013-10-08 |
2015-04-16 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
US10413520B2
(en)
|
2014-01-29 |
2019-09-17 |
Crystalgenomics, Inc. |
Oral pharmacological composition including 5-{4-(amino sulfonyl)phenyl}-2,2-dimethyl-4-(3-fluorophenyl)-3(2H)-furanone having crystalline structure with excellent stability
|
KR101446601B1
(en)
*
|
2014-01-29 |
2014-10-07 |
크리스탈지노믹스(주) |
Pharmaceutical composition and capsule formulation comprising 5-(4-(aminosulfonyl)phenyl)-2,2-dimethyl-4-(3-fluorophenyl)-3(2h)-furanone
|
TWI690521B
(en)
|
2014-04-07 |
2020-04-11 |
美商同步製藥公司 |
Carbazole-containing amides, carbamates, and ureas as cryptochrome modulators
|
JO3589B1
(en)
|
2014-08-06 |
2020-07-05 |
Novartis Ag |
Protein kinase c inhibitors and methods of their use
|
GB201417500D0
(en)
|
2014-10-03 |
2014-11-19 |
Convergence Pharmaceuticals |
Novel use
|
GB201417499D0
(en)
|
2014-10-03 |
2014-11-19 |
Convergence Pharmaceuticals |
Novel use
|
GB201417497D0
(en)
|
2014-10-03 |
2014-11-19 |
Convergence Pharmaceuticals |
Novel use
|
RU2563876C1
(en)
*
|
2014-11-11 |
2015-09-27 |
Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Санкт-Петербургский государственный университет" (СПбГУ) |
Method of producing 2,2-dialkyl-4,5-diarylfuran-3(2h)-ones
|
EP3267996B1
(en)
|
2015-03-12 |
2020-11-11 |
Merck Sharp & Dohme Corp. |
Pyrazolopyrimidine inhibitors of irak4 activity
|
EP3268367B8
(en)
|
2015-03-12 |
2022-11-16 |
Merck Sharp & Dohme LLC |
Carboxamide inhibitors of irak4 activity
|
WO2016144849A1
(en)
|
2015-03-12 |
2016-09-15 |
Merck Sharp & Dohme Corp. |
Thienopyrazine inhibitors of irak4 activity
|
WO2016177776A1
(en)
|
2015-05-04 |
2016-11-10 |
Academisch Medisch Centrum |
Biomarkers for the detection of aspirin insensitivity
|
US10202435B2
(en)
|
2016-04-15 |
2019-02-12 |
Alder Biopharmaceuticals, Inc. |
Anti-PACAP antibodies and uses thereof
|
US9737530B1
(en)
|
2016-06-23 |
2017-08-22 |
Collegium Pharmaceutical, Inc. |
Process of making stable abuse-deterrent oral formulations
|
WO2018015279A1
(en)
|
2016-07-21 |
2018-01-25 |
Unilever Plc |
Lactams for the treatment of respiratory tract infections
|
EP3487496A1
(en)
|
2016-07-21 |
2019-05-29 |
Unilever PLC |
4-(4-chlorophenyl)-5-methylene-pyrrol-2-one and 5-methylene-4-(p-tolyl)pyrrol-2-one for use in the treatment of gram negative bacterial infections
|
BR112019001130A2
(en)
|
2016-07-21 |
2019-04-30 |
Unilever Nv |
use of lactam and pharmaceutical composition
|
US10947234B2
(en)
|
2017-11-08 |
2021-03-16 |
Merck Sharp & Dohme Corp. |
PRMT5 inhibitors
|
WO2019177690A1
(en)
|
2018-03-12 |
2019-09-19 |
Zoetis Services Llc |
Anti-ngf antibodies and methods thereof
|
EP3833668A4
(en)
|
2018-08-07 |
2022-05-11 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
WO2020033284A1
(en)
|
2018-08-07 |
2020-02-13 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
EP3852732A1
(en)
|
2018-09-19 |
2021-07-28 |
ModernaTX, Inc. |
Peg lipids and uses thereof
|
JP2022500543A
(en)
|
2018-09-19 |
2022-01-04 |
モデルナティーエックス, インコーポレイテッド |
High-purity PEG lipids and their use
|
CN113660934A
(en)
|
2018-11-21 |
2021-11-16 |
特默罗制药股份有限公司 |
Purified forms, methods of preparation and uses of rofecoxib
|
CN110452198B
(en)
*
|
2019-09-03 |
2021-03-26 |
山东鲁抗舍里乐药业有限公司 |
Preparation method of feloxicib
|
CN110452199B
(en)
*
|
2019-09-03 |
2021-03-30 |
山东鲁抗舍里乐药业有限公司 |
Preparation method of feloxicib
|
US10945992B1
(en)
|
2019-11-13 |
2021-03-16 |
Tremeau Pharmaceuticals, Inc. |
Dosage forms of rofecoxib and related methods
|
AU2020408148A1
(en)
|
2019-12-17 |
2022-06-16 |
Merck Sharp & Dohme Llc |
PRMT5 inhibitors
|
CN114014824B
(en)
*
|
2020-12-09 |
2023-06-13 |
上海科技大学 |
Application of heterocyclic compound
|
CN117015540A
(en)
*
|
2021-03-11 |
2023-11-07 |
南京明德新药研发有限公司 |
Thiophene compound and application thereof
|
WO2022195579A1
(en)
|
2021-03-15 |
2022-09-22 |
Saul Yedgar |
Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory diseases
|
US11161833B1
(en)
|
2021-04-09 |
2021-11-02 |
Tremeau Pharmaceuticals, Inc. |
Deuterated etoricoxib, methods of manufacture, and use thereof
|
WO2023026245A1
(en)
|
2021-08-27 |
2023-03-02 |
H. Lundbeck A/S |
Treatment of cluster headache using anti-cgrp antibodies
|