CA2165343A1 - A method and apparatus for calculating a coagulation characteristic of a sample of blood, a blood fraction or a control - Google Patents

A method and apparatus for calculating a coagulation characteristic of a sample of blood, a blood fraction or a control

Info

Publication number
CA2165343A1
CA2165343A1 CA002165343A CA2165343A CA2165343A1 CA 2165343 A1 CA2165343 A1 CA 2165343A1 CA 002165343 A CA002165343 A CA 002165343A CA 2165343 A CA2165343 A CA 2165343A CA 2165343 A1 CA2165343 A1 CA 2165343A1
Authority
CA
Canada
Prior art keywords
values
stored
blood
envelope values
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002165343A
Other languages
French (fr)
Other versions
CA2165343C (en
Inventor
Rick L. Collins
Zindel Herbert Heller
Edna Probst
Stefan Weinert
Martin T. Gerber
James L. Maxwell
Loy Maugh Vail
Morris J. Young
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics Operations Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2165343A1 publication Critical patent/CA2165343A1/en
Application granted granted Critical
Publication of CA2165343C publication Critical patent/CA2165343C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/22—Blood coagulation

Abstract

A method for calculating a coagulation characteristic of a sample (513) of blood, a blood fraction, or a control comprises generating an output signal (501) indicative of coagulation of the sample, sampling the output signal (501) at a sampling rate for a predetermined time to provide a plurality of sample signal values, storing (500) the sampled signal values, rectifying (604) the stored sampled signal values to provide a plurality of envelope values (503), and storing (606) the envelope values (503). The stored envelope values (503) are examined in reverse time order to determine a slope of the envelope (503) at each of the stored envelope values (503). All relative maximum is in the stored envelope values (503) are identified. A range of stored envelope values (503) corresponding to each relative maximum is determined. The identified relative maxima are compared (732, 734, 736, 738) to locate an absolute maximum in the stored envelope values (503). The coagulation characteristic is then calculated from the stored envelope values within the predetermined range of envelope values corresponding to the absolute maximum.
CA002165343A 1993-08-31 1994-08-18 A method and apparatus for calculating a coagulation characteristic of a sample of blood, a blood fraction or a control Expired - Fee Related CA2165343C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/114,897 1993-08-31
US08/114,897 US5526111A (en) 1993-08-31 1993-08-31 Method and apparatus for calculating a coagulation characteristic of a sample of blood a blood fraction or a control
PCT/US1994/009321 WO1995006919A1 (en) 1993-08-31 1994-08-18 Method and apparatus for operating a medical instrument

Publications (2)

Publication Number Publication Date
CA2165343A1 true CA2165343A1 (en) 1995-03-09
CA2165343C CA2165343C (en) 2003-12-16

Family

ID=22358089

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002165343A Expired - Fee Related CA2165343C (en) 1993-08-31 1994-08-18 A method and apparatus for calculating a coagulation characteristic of a sample of blood, a blood fraction or a control

Country Status (7)

Country Link
US (1) US5526111A (en)
EP (1) EP0720742B1 (en)
JP (1) JP3390009B2 (en)
CA (1) CA2165343C (en)
DE (1) DE69429355T2 (en)
ES (1) ES2169084T3 (en)
WO (1) WO1995006919A1 (en)

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Also Published As

Publication number Publication date
CA2165343C (en) 2003-12-16
DE69429355T2 (en) 2002-09-19
JP3390009B2 (en) 2003-03-24
ES2169084T3 (en) 2002-07-01
EP0720742A1 (en) 1996-07-10
EP0720742B1 (en) 2001-12-05
WO1995006919A1 (en) 1995-03-09
JPH09502266A (en) 1997-03-04
DE69429355D1 (en) 2002-01-17
US5526111A (en) 1996-06-11
EP0720742A4 (en) 1997-05-07

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Effective date: 20100818