CA2164850A1 - Wearable iontophoresis system - Google Patents

Wearable iontophoresis system

Info

Publication number
CA2164850A1
CA2164850A1 CA2164850A CA2164850A CA2164850A1 CA 2164850 A1 CA2164850 A1 CA 2164850A1 CA 2164850 A CA2164850 A CA 2164850A CA 2164850 A CA2164850 A CA 2164850A CA 2164850 A1 CA2164850 A1 CA 2164850A1
Authority
CA
Canada
Prior art keywords
connector
control housing
retaining
patch
permits
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2164850A
Other languages
French (fr)
Other versions
CA2164850C (en
Inventor
Karl Dallas Kirk, Iii
James Robert Toleman
Robert Peter Pandorf
Ellen R. Cohen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vyteris Inc
Original Assignee
Karl Dallas Kirk, Iii
James Robert Toleman
Robert Peter Pandorf
Ellen R. Cohen
Human Factors Industrial Design, Inc.
Becton, Dickinson And Company
Drug Delivery Technologies, Inc.
Vyteris, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Karl Dallas Kirk, Iii, James Robert Toleman, Robert Peter Pandorf, Ellen R. Cohen, Human Factors Industrial Design, Inc., Becton, Dickinson And Company, Drug Delivery Technologies, Inc., Vyteris, Inc. filed Critical Karl Dallas Kirk, Iii
Publication of CA2164850A1 publication Critical patent/CA2164850A1/en
Application granted granted Critical
Publication of CA2164850C publication Critical patent/CA2164850C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode

Abstract

A wearable iontophoresis system includes a control housing having a connector and an iontophoretic drug delivery patch for placement against the skin of a patient. The patch has a device for retaining the control housing connector which permits the connector to be removably attached to the patch. The control housing also has at least a power supply device and a current delivery device. The control housing has top and bottom surfaces wherein the top surface has raised, recessed and sloping regions. The thickness of the connector is tapered from a second end to a first end. Furthermore, the second end of the connector is attached to the control housing and oriented so that the first end is unattached to the control housing and proximate to the control housing bottom surface. The iontophoretic drug delivery patch includes top and bottom surfaces wherein mounted to the top surface is the device for retaining the control housing connector. The control housing connector retaining device has first and second open ends and a cavity for placement therein of the connector. The taper of the connector permits it to be easily inserted through one of the first and second open ends and into the control housing connector retaining device cavity.
CA002164850A 1993-06-08 1994-02-18 Wearable iontophoresis system Expired - Fee Related CA2164850C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/073,923 US5458569A (en) 1993-06-08 1993-06-08 Wearable iontophoresis system
US08/073,923 1993-06-08
PCT/US1994/001809 WO1994028965A1 (en) 1993-06-08 1994-02-18 Wearable iontophoresis system

Publications (2)

Publication Number Publication Date
CA2164850A1 true CA2164850A1 (en) 1994-12-22
CA2164850C CA2164850C (en) 2000-10-10

Family

ID=22116611

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002164850A Expired - Fee Related CA2164850C (en) 1993-06-08 1994-02-18 Wearable iontophoresis system

Country Status (8)

Country Link
US (1) US5458569A (en)
EP (1) EP0702579B1 (en)
JP (1) JP2802170B2 (en)
AT (1) ATE192663T1 (en)
AU (1) AU7013494A (en)
CA (1) CA2164850C (en)
DE (1) DE69424413T2 (en)
WO (1) WO1994028965A1 (en)

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US5795321A (en) * 1994-09-30 1998-08-18 Becton Dickinson And Company Iontophoretic drug delivery system, including removable controller
US5879322A (en) * 1995-03-24 1999-03-09 Alza Corporation Self-contained transdermal drug delivery device
CH693606A5 (en) * 1995-05-15 2003-11-14 Alza Corp Electrotransport device having reusable controller.
US5978701A (en) * 1995-06-02 1999-11-02 Alza Corporation Electrotransport device with separable controller and drug unit and method of setting controller output
CA2233197A1 (en) * 1995-09-28 1997-04-03 Becton, Dickinson And Company Iontophoretic drug delivery system, including reusable device
US5676648A (en) 1996-05-08 1997-10-14 The Aps Organization, Llp Iontophoretic drug delivery apparatus and method for use
US6385487B1 (en) 1996-05-08 2002-05-07 Biophoretic Therapeutic Systems, Llc Methods for electrokinetic delivery of medicaments
US6086572A (en) * 1996-05-31 2000-07-11 Alza Corporation Electrotransport device and method of setting output
US5961483A (en) * 1996-06-19 1999-10-05 Sage; Burton H. Iontophoretic delivery of cell adhesion inhibitors
US5991655A (en) * 1997-03-03 1999-11-23 Drug Delivery Systems, Inc. Iontophoretic drug delivery device and method of manufacturing the same
US6119036A (en) 1997-03-26 2000-09-12 The Board Of Regents Of The University Of Oklahoma Iontophoretic transdermal delivery device
US5873850A (en) * 1997-05-29 1999-02-23 Becton Dickinson And Company Locking and disfiguring mechanism for an iontophoretic system
ATE373957T1 (en) 1997-10-09 2007-10-15 Univ Emory METHOD AND DEVICE FOR TRANSDERMAL ADMINISTRATION OF LITHIUM
USRE37796E1 (en) 1997-12-16 2002-07-23 Biophoretic Therapeutic Systems, Llc Methods for iontophoretic delivery of antiviral agents
EP1115454B1 (en) * 1998-08-31 2006-10-25 Travanti Pharma Inc Controlled dosage drug delivery system
US6148231A (en) * 1998-09-15 2000-11-14 Biophoretic Therapeutic Systems, Llc Iontophoretic drug delivery electrodes and method
EP1121059A4 (en) * 1998-09-15 2006-04-05 Biophoretic Therapeutic System Iontophoretic drug delivery electrodes
US6475514B1 (en) 1998-12-03 2002-11-05 Andrew Blitzer Athletic patch
US6317630B1 (en) 1999-01-29 2001-11-13 Yossi Gross Drug delivery device
US6477410B1 (en) 2000-05-31 2002-11-05 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery of medicaments
US6553253B1 (en) 1999-03-12 2003-04-22 Biophoretic Therapeutic Systems, Llc Method and system for electrokinetic delivery of a substance
US6792306B2 (en) 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
JP2000316991A (en) 1999-05-13 2000-11-21 Hisamitsu Pharmaceut Co Inc Electrode structural body for iontophoresis device and its manufacture
US6687536B1 (en) * 1999-12-09 2004-02-03 Iomed, Inc. Connection system for an iontophoretic drug delivery device
CA2325195A1 (en) * 1999-12-09 2001-06-09 Iomed, Inc. Connection system including a tether for an iontophoretic drug delivery device
US6421561B1 (en) * 1999-12-30 2002-07-16 Birch Point Medical, Inc. Rate adjustable drug delivery system
DE10025890A1 (en) * 2000-05-25 2001-11-29 Euro Celtique Sa Dosage of transdermal drug systems
US6560483B1 (en) 2000-10-18 2003-05-06 Minnesota High-Tech Resources, Llc Iontophoretic delivery patch
US6653014B2 (en) 2001-05-30 2003-11-25 Birch Point Medical, Inc. Power sources for iontophoretic drug delivery systems
US6745071B1 (en) 2003-02-21 2004-06-01 Birch Point Medical, Inc. Iontophoretic drug delivery system
US7856263B2 (en) * 2005-04-22 2010-12-21 Travanti Pharma Inc. Transdermal systems for the delivery of therapeutic agents including granisetron using iontophoresis
WO2007013310A1 (en) * 2005-07-25 2007-02-01 Sony Corporation Communication system, communication apparatus, method and program
US20090221985A1 (en) * 2005-10-19 2009-09-03 Shmuel Bukshpan System for iontophoretic transdermal delivery of polymeric agents and methods of use thereof
CA2935569A1 (en) * 2006-04-13 2007-10-25 Teva Pharmaceuticals International Gmbh Transdermal methods and systems for the delivery of anti-migraine compounds
US7904146B2 (en) * 2006-11-13 2011-03-08 Travanti Pharma Inc. Transdermal systems for the delivery of ionic agents directly to open wounds and surgically repaired incisions
US20080234627A1 (en) * 2007-03-22 2008-09-25 Wanda Dent Pivotally engaged multiple part electrotransport drug delivery device
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
EP2644228A1 (en) 2007-06-27 2013-10-02 The General Hospital Corporation Method and apparatus for optical inhibition of photodynamic therapy
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
US8366600B2 (en) * 2008-06-19 2013-02-05 Nupathe Inc. Polyamine enhanced formulations for triptan compound iontophoresis
US8155737B2 (en) * 2008-06-19 2012-04-10 Nupathe, Inc. Pharmacokinetics of iontophoretic sumatriptan administration
KR101674904B1 (en) 2009-02-26 2016-11-10 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 Interventional drug delivery system and associated methods
CN102573489A (en) 2009-08-10 2012-07-11 纽帕特公司 Methods for iontophoretically treating nausea and migraine
WO2011046927A1 (en) * 2009-10-13 2011-04-21 Nupathe,Inc. Transdermal methods and systems for the delivery of rizatriptan
EP2407193A1 (en) * 2010-07-12 2012-01-18 Roche Diagnostics GmbH Medicinal device with multiple part housing
CA2817824A1 (en) 2010-11-23 2012-05-31 Nupathe, Inc. User-activated self-contained co-packaged iontophoretic drug delivery system
US8428709B1 (en) 2012-06-11 2013-04-23 Incline Therapeutics, Inc. Current control for electrotransport drug delivery
US8428708B1 (en) 2012-05-21 2013-04-23 Incline Therapeutics, Inc. Self-test for analgesic product
US8301238B2 (en) 2011-03-31 2012-10-30 Incline Therapeutics, Inc. Two-part electrotransport device

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US4622031A (en) * 1983-08-18 1986-11-11 Drug Delivery Systems Inc. Indicator for electrophoretic transcutaneous drug delivery device
US4856188A (en) * 1984-10-12 1989-08-15 Drug Delivery Systems Inc. Method for making disposable and/or replenishable transdermal drug applicators
US5224928A (en) * 1983-08-18 1993-07-06 Drug Delivery Systems Inc. Mounting system for transdermal drug applicator
US4919648A (en) * 1983-08-18 1990-04-24 Drug Delivery Systems Inc. High tack drug patch
US5135479A (en) * 1983-08-18 1992-08-04 Drug Delivery Systems, Inc. Programmable control and mounting system for transdermal drug applicator
DK150841C (en) * 1984-12-19 1988-07-11 Medicotest Systemer As CONNECTOR FOR ESTABLISHING ELECTRICAL CONNECTION WITH A disposable skin electrode
ATE80048T1 (en) * 1985-06-10 1992-09-15 Drug Delivery Systems Inc PROGRAMMABLE CONTROL AND CONSTRUCTION SYSTEM OF A TRANSDERMIC DRUG DELIVERY DEVICE.
US4725263A (en) * 1986-07-31 1988-02-16 Medtronic, Inc. Programmable constant current source transdermal drug delivery system
US4700997A (en) * 1986-11-14 1987-10-20 Minnesota Mining And Manufacturing Company Electrical connector
US4931046A (en) * 1987-05-15 1990-06-05 Newman Martin H Iontophoresis drug delivery system
US4942883A (en) * 1987-09-29 1990-07-24 Newman Martin H Drug delivery device
US4950229A (en) * 1989-09-25 1990-08-21 Becton, Dickinson And Company Apparatus for an electrode used for iontophoresis

Also Published As

Publication number Publication date
WO1994028965A1 (en) 1994-12-22
JP2802170B2 (en) 1998-09-24
CA2164850C (en) 2000-10-10
JPH08508915A (en) 1996-09-24
ATE192663T1 (en) 2000-05-15
EP0702579A4 (en) 1997-01-15
DE69424413D1 (en) 2000-06-15
DE69424413T2 (en) 2001-01-25
US5458569A (en) 1995-10-17
EP0702579A1 (en) 1996-03-27
AU7013494A (en) 1995-01-03
EP0702579B1 (en) 2000-05-10

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Legal Events

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EEER Examination request
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