CA2163560A1 - Indwelling catheter with stable enzyme coating - Google Patents

Indwelling catheter with stable enzyme coating

Info

Publication number
CA2163560A1
CA2163560A1 CA002163560A CA2163560A CA2163560A1 CA 2163560 A1 CA2163560 A1 CA 2163560A1 CA 002163560 A CA002163560 A CA 002163560A CA 2163560 A CA2163560 A CA 2163560A CA 2163560 A1 CA2163560 A1 CA 2163560A1
Authority
CA
Canada
Prior art keywords
coating
enzyme
catheter
indwelling catheter
stable enzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002163560A
Other languages
French (fr)
Other versions
CA2163560C (en
Inventor
William P. Van Antwerp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medtronic Minimed Inc
Original Assignee
William P. Van Antwerp
Minimed Technologies, Ltd. A California Limited Partnership D/B/A Minimed Technologies
Minimed Inc.
Medtronic Minimed, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by William P. Van Antwerp, Minimed Technologies, Ltd. A California Limited Partnership D/B/A Minimed Technologies, Minimed Inc., Medtronic Minimed, Inc. filed Critical William P. Van Antwerp
Publication of CA2163560A1 publication Critical patent/CA2163560A1/en
Application granted granted Critical
Publication of CA2163560C publication Critical patent/CA2163560C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0017—Catheters; Hollow probes specially adapted for long-term hygiene care, e.g. urethral or indwelling catheters to prevent infections

Abstract

An improved indwelling catheter (10) adapted for long-term usage includes a stable enzyme coating (14, 40) to prevent occlusion of the catheter lumen (16). The enzyme coating includes a fibrinolytic and/or lipolytic enzyme incorporated in a catheter coating to resist or control proteolytic degradation, thereby maintaining the enzyme in an active state for dissolving clots and occlusions within the catheter lumen over an extended period of time.
CA002163560A 1994-04-01 1995-03-20 Indwelling catheter with stable enzyme coating Expired - Fee Related CA2163560C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/221,934 1994-04-01
US08/221,934 US5505713A (en) 1994-04-01 1994-04-01 Indwelling catheter with stable enzyme coating
PCT/US1995/003550 WO1995026765A1 (en) 1994-04-01 1995-03-20 Indwelling catheter with stable enzyme coating

Publications (2)

Publication Number Publication Date
CA2163560A1 true CA2163560A1 (en) 1995-10-12
CA2163560C CA2163560C (en) 2009-05-19

Family

ID=22830035

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002163560A Expired - Fee Related CA2163560C (en) 1994-04-01 1995-03-20 Indwelling catheter with stable enzyme coating

Country Status (6)

Country Link
US (4) US5505713A (en)
EP (1) EP0703799B1 (en)
JP (1) JP3884475B2 (en)
CA (1) CA2163560C (en)
DE (1) DE69533236T2 (en)
WO (1) WO1995026765A1 (en)

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DE69533236D1 (en) 2004-08-12
JP3884475B2 (en) 2007-02-21
US5538511A (en) 1996-07-23
JPH09503951A (en) 1997-04-22
EP0703799A1 (en) 1996-04-03
EP0703799B1 (en) 2004-07-07
CA2163560C (en) 2009-05-19
EP0703799A4 (en) 2000-10-04
DE69533236T2 (en) 2004-11-04
WO1995026765A1 (en) 1995-10-12
US5505713A (en) 1996-04-09
US5788678A (en) 1998-08-04
US5868720A (en) 1999-02-09

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