CA2149216A1 - Iontophoretic Structure for Medical Devices - Google Patents

Iontophoretic Structure for Medical Devices

Info

Publication number
CA2149216A1
CA2149216A1 CA2149216A CA2149216A CA2149216A1 CA 2149216 A1 CA2149216 A1 CA 2149216A1 CA 2149216 A CA2149216 A CA 2149216A CA 2149216 A CA2149216 A CA 2149216A CA 2149216 A1 CA2149216 A1 CA 2149216A1
Authority
CA
Canada
Prior art keywords
galvanic
separated
medical devices
catheter
dissimilar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2149216A
Other languages
French (fr)
Other versions
CA2149216C (en
Inventor
Fredric L. Milder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PATHAGON Inc
Original Assignee
Fredric L. Milder
Implemed, Inc.
Benefit Capital Management Corporation As Investment Manager For The Pru Dential Insurance Company Of America, Separate Account No. Vca-Ga-5028
Bridge Blood Technologies, Llc
Pathagon, Inc.
Bioenvision Acquisition Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fredric L. Milder, Implemed, Inc., Benefit Capital Management Corporation As Investment Manager For The Pru Dential Insurance Company Of America, Separate Account No. Vca-Ga-5028, Bridge Blood Technologies, Llc, Pathagon, Inc., Bioenvision Acquisition Corp. filed Critical Fredric L. Milder
Priority to CA002313440A priority Critical patent/CA2313440C/en
Publication of CA2149216A1 publication Critical patent/CA2149216A1/en
Application granted granted Critical
Publication of CA2149216C publication Critical patent/CA2149216C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A61N1/306—Arrangements where at least part of the apparatus is introduced into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details

Abstract

An iontophozetic structure for medical devices is provided that uses controlled electrical current derived from two dissimilar galvanic materials to drive oligodynamic metal ions (38) into olution to kill bacteria on and near the device to which the structure is affixed. In one embodiment, a first galvanic material (32) separated from a second galvanic material (34) by a resistive material (30) produces an anti-bacterial current flow when placed in contact with an electrolytic fluid. In another embodiment, a cylindrical elastomeric catheter (10) incorpotates a first and a second galvanic material separated by a resistive material which controls a current flow between the galvanic materials when the catheter is immersed in an electrolytic fluid. The galvanic materials can be dissimilar metal powders embedded in a conductive polymer substrate that forms an iontophoretic composite material, or dissimilar metals arranged in layers (76; 80) separated by a resistive layer (78). In yet another embodiment, the iontophotetie composite material is configured as an infection control sleeve (60) that covers a portion of an ordinary catheter or cannula. Methods of protecting implantabte medical devices and body structures with the iontophoretic strucriaxes are also provided.
CA002149216A 1992-11-12 1993-11-10 Iontophoretic structure for medical devices Expired - Lifetime CA2149216C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002313440A CA2313440C (en) 1992-11-12 1993-11-10 Methods of making an antibacterial device

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US975,597 1992-11-12
US07/975,597 US5322520A (en) 1992-11-12 1992-11-12 Iontophoretic structure for medical devices
PCT/US1993/010911 WO1994011058A1 (en) 1992-11-12 1993-11-10 Iontophoretic structure for medical devices

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA002313440A Division CA2313440C (en) 1992-11-12 1993-11-10 Methods of making an antibacterial device

Publications (2)

Publication Number Publication Date
CA2149216A1 true CA2149216A1 (en) 1994-05-26
CA2149216C CA2149216C (en) 2000-10-17

Family

ID=25523178

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002149216A Expired - Lifetime CA2149216C (en) 1992-11-12 1993-11-10 Iontophoretic structure for medical devices

Country Status (5)

Country Link
US (3) US5322520A (en)
EP (1) EP0678047A4 (en)
JP (1) JP3555684B2 (en)
CA (1) CA2149216C (en)
WO (1) WO1994011058A1 (en)

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CA2149216C (en) 2000-10-17
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US5322520A (en) 1994-06-21

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