CA2145302A1 - Peptide proteinaceous drug nasal powder composition - Google Patents

Peptide proteinaceous drug nasal powder composition

Info

Publication number
CA2145302A1
CA2145302A1 CA002145302A CA2145302A CA2145302A1 CA 2145302 A1 CA2145302 A1 CA 2145302A1 CA 002145302 A CA002145302 A CA 002145302A CA 2145302 A CA2145302 A CA 2145302A CA 2145302 A1 CA2145302 A1 CA 2145302A1
Authority
CA
Canada
Prior art keywords
powder composition
proteinaceous drug
nasal powder
peptide proteinaceous
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002145302A
Other languages
French (fr)
Other versions
CA2145302C (en
Inventor
Masahiko Dohi
Yoshihisa Nishibe
Yuji Makino
Yoshiki Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2145302A1 publication Critical patent/CA2145302A1/en
Application granted granted Critical
Publication of CA2145302C publication Critical patent/CA2145302C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B60—VEHICLES IN GENERAL
    • B60H—ARRANGEMENTS OF HEATING, COOLING, VENTILATING OR OTHER AIR-TREATING DEVICES SPECIALLY ADAPTED FOR PASSENGER OR GOODS SPACES OF VEHICLES
    • B60H1/00—Heating, cooling or ventilating [HVAC] devices
    • B60H1/00485—Valves for air-conditioning devices, e.g. thermostatic valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/25—Growth hormone-releasing factor [GH-RF] (Somatoliberin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose

Abstract

A peptide proteinaceous drug nasal powder composition containing (i) an absorption accelerant comprised of a compound, or its salt, having in its molecule a group expressed by the formula (I):

(see formula I) wherein, (see formula II) indicates a cyclohexane ring or a benzene ring which may be substituted at least one of its 3-position, 4-position, and 5-position and n is an integer of 1 to 3 and (ii) a therapeutically effective amount of a peptide proteinaceous drug.
CA002145302A 1993-07-30 1994-07-29 Peptide proteinaceous drug nasal powder composition Expired - Fee Related CA2145302C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP5/206922 1993-07-30
JP20692293 1993-07-30
JP5/235841 1993-08-30
JP23584193 1993-08-30
JP6/1644 1994-01-12
JP164494 1994-01-12
PCT/JP1994/001257 WO1995003818A1 (en) 1993-07-30 1994-07-29 Powder for nasal administration of peptidic or proteinaceous drug

Publications (2)

Publication Number Publication Date
CA2145302A1 true CA2145302A1 (en) 1995-02-09
CA2145302C CA2145302C (en) 2008-10-28

Family

ID=27275015

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002145302A Expired - Fee Related CA2145302C (en) 1993-07-30 1994-07-29 Peptide proteinaceous drug nasal powder composition

Country Status (9)

Country Link
US (1) US5578324A (en)
EP (1) EP0667163B1 (en)
JP (1) JP2974412B2 (en)
KR (1) KR100327563B1 (en)
AT (1) ATE215377T1 (en)
CA (1) CA2145302C (en)
DE (1) DE69430295T2 (en)
ES (1) ES2171459T3 (en)
WO (1) WO1995003818A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109996530A (en) * 2016-11-28 2019-07-09 宝丽化成工业有限公司 Wrinkle-diminishing agent

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US5981719A (en) 1993-03-09 1999-11-09 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
EP0803255A4 (en) * 1994-06-03 1999-06-30 Tsumura & Co Medicinal composition
JP3263598B2 (en) * 1995-11-01 2002-03-04 有限会社ドット Bioactive peptide composition for nasal absorption
WO1997031626A1 (en) * 1996-02-27 1997-09-04 Teijin Limited Powdery composition for nasal administration
ATE331532T1 (en) * 1998-08-26 2006-07-15 Teijin Ltd POWDERED PERNASALE PRODUCTS
AU2003273615B2 (en) * 2002-06-11 2010-07-29 Brigham And Women's Hospital Neuroprotective synergy of erythropoietin and insulin-like growth factor
US7812120B2 (en) * 2003-03-21 2010-10-12 Par Pharmaceutical, Inc. Nasal calcitonin formulations containing chlorobutanol
JP2008019245A (en) * 2006-06-15 2008-01-31 Japan Science & Technology Agency Intranasal agent for prevention and treatment of alzheimer's disease containing humanin derivative or fused peptide composed of humanin derivative and neurotropic peptide as active component
CA3101313C (en) * 2018-05-29 2023-01-24 Pola Chemical Industries, Inc. Skin whitening agent comprising an aminocarboxylic acid derivative
JP7102657B2 (en) * 2018-05-29 2022-07-20 ポーラ化成工業株式会社 Wrinkle improving composition
JP7102658B2 (en) * 2018-05-29 2022-07-20 ポーラ化成工業株式会社 Whitening composition

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4258030A (en) * 1979-03-07 1981-03-24 Zeria-Shinyaku Kogyo Kabushiki Kaisha Urokinase preparation for oral administration
DE3514508A1 (en) * 1985-04-22 1986-10-30 Kailash Kumar Prof. Dr. 2359 Lentföhrden Gauri Use of dopamine and its esters for the treatment of glaucoma
JPH01308235A (en) * 1988-06-03 1989-12-12 Yamanouchi Pharmaceut Co Ltd Human growth hormone for transnasal administration
GB9013448D0 (en) * 1990-06-15 1990-08-08 Sandoz Ltd Pharmaceutical resorption-improved somatostatin compositions,their preparation and use
JPH04235923A (en) * 1991-01-16 1992-08-25 Kyowa Hakko Kogyo Co Ltd Pharmaceutical preparation for nasal administration
JPH04300817A (en) * 1991-03-27 1992-10-23 Shiseido Co Ltd Composition for oral cavity
JPH0558908A (en) * 1991-09-05 1993-03-09 Mitsubishi Kasei Corp Medicinal composition for nasal drops of calcitonin
JP3090353B2 (en) * 1991-09-17 2000-09-18 旭化成工業株式会社 Emulsion for nasal administration containing parathyroid hormones
JP3047948B2 (en) * 1992-12-07 2000-06-05 株式会社ツムラ Composition for nasal administration of peptides

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109996530A (en) * 2016-11-28 2019-07-09 宝丽化成工业有限公司 Wrinkle-diminishing agent
CN109996530B (en) * 2016-11-28 2022-04-05 宝丽化成工业有限公司 Wrinkle-improving agent

Also Published As

Publication number Publication date
ES2171459T3 (en) 2002-09-16
WO1995003818A1 (en) 1995-02-09
ATE215377T1 (en) 2002-04-15
EP0667163A4 (en) 2000-04-19
KR950703352A (en) 1995-09-20
DE69430295D1 (en) 2002-05-08
CA2145302C (en) 2008-10-28
EP0667163A1 (en) 1995-08-16
US5578324A (en) 1996-11-26
EP0667163B1 (en) 2002-04-03
JP2974412B2 (en) 1999-11-10
DE69430295T2 (en) 2002-10-31
KR100327563B1 (en) 2002-08-24

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed
MKLA Lapsed

Effective date: 20110729