CA2141704A1 - Solutions aqueuses concentrees d'argatroban - Google Patents

Solutions aqueuses concentrees d'argatroban

Info

Publication number
CA2141704A1
CA2141704A1 CA002141704A CA2141704A CA2141704A1 CA 2141704 A1 CA2141704 A1 CA 2141704A1 CA 002141704 A CA002141704 A CA 002141704A CA 2141704 A CA2141704 A CA 2141704A CA 2141704 A1 CA2141704 A1 CA 2141704A1
Authority
CA
Canada
Prior art keywords
concentrated aqueous
argatroban
esp
solutions
argatroban solutions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002141704A
Other languages
English (en)
Other versions
CA2141704C (fr
Inventor
Frederic Andre
Veronique Avril
Jean Montel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Pharma Corp
Original Assignee
Frederic Andre
Veronique Avril
Jean Montel
Synthelabo
Sanofi-Synthelabo
Mitsubishi-Tokyo Pharmaceuticals, Inc.
Mitsubishi Pharma Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Frederic Andre, Veronique Avril, Jean Montel, Synthelabo, Sanofi-Synthelabo, Mitsubishi-Tokyo Pharmaceuticals, Inc., Mitsubishi Pharma Corporation filed Critical Frederic Andre
Publication of CA2141704A1 publication Critical patent/CA2141704A1/fr
Application granted granted Critical
Publication of CA2141704C publication Critical patent/CA2141704C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Abstract

Solutions aqueuses concentrées d'argatroban contenant de l'argatroban, un agent formateur de micelles et une substance lipoïde.
CA002141704A 1994-02-03 1995-02-02 Solutions aqueuses concentrees d'argatroban Expired - Lifetime CA2141704C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9401195A FR2715566B1 (fr) 1994-02-03 1994-02-03 Solutions aqueuses concentrées d'argatroban.
FR94.01195 1994-02-03

Publications (2)

Publication Number Publication Date
CA2141704A1 true CA2141704A1 (fr) 1995-08-04
CA2141704C CA2141704C (fr) 2001-07-03

Family

ID=9459714

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002141704A Expired - Lifetime CA2141704C (fr) 1994-02-03 1995-02-02 Solutions aqueuses concentrees d'argatroban

Country Status (25)

Country Link
US (1) US5679690A (fr)
EP (1) EP0669131B1 (fr)
JP (1) JP3027103B2 (fr)
KR (1) KR100257692B1 (fr)
CN (1) CN1054743C (fr)
AT (1) ATE179327T1 (fr)
AU (1) AU687133B2 (fr)
CA (1) CA2141704C (fr)
CZ (1) CZ284611B6 (fr)
DE (1) DE69509279T2 (fr)
DK (1) DK0669131T3 (fr)
ES (1) ES2132547T3 (fr)
FI (1) FI950459A (fr)
FR (1) FR2715566B1 (fr)
GR (1) GR3030149T3 (fr)
HK (1) HK1013623A1 (fr)
HU (1) HU218220B (fr)
IL (1) IL112527A (fr)
NO (1) NO307324B1 (fr)
NZ (1) NZ270445A (fr)
PL (1) PL178586B1 (fr)
RU (1) RU2136282C1 (fr)
SK (1) SK12795A3 (fr)
TW (1) TW436295B (fr)
ZA (1) ZA95837B (fr)

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CA2291735A1 (fr) * 1997-05-27 1998-12-03 Takahiro Ogawa Preparations aqueuses contenant de l'israpafant
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
FR2793412B1 (fr) * 1999-05-11 2001-07-27 Synthelabo Formulations galeniques d'argatroban pour administration sous-cutanee
KR100399373B1 (ko) * 2000-12-20 2003-09-26 주식회사 아이센스 콜란산 고리를 포함하는 디글라이콜릭 디아마이드 유도체,그의 제조방법 및 용도
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
US7041468B2 (en) 2001-04-02 2006-05-09 Therasense, Inc. Blood glucose tracking apparatus and methods
US6984395B2 (en) * 2001-04-11 2006-01-10 Qlt, Inc. Drug delivery system for hydrophobic drugs
US7811231B2 (en) 2002-12-31 2010-10-12 Abbott Diabetes Care Inc. Continuous glucose monitoring system and methods of use
CN100344624C (zh) * 2003-03-20 2007-10-24 三菱制药株式会社 含有精氨酰胺类的医药制剂
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
WO2005089103A2 (fr) 2004-02-17 2005-09-29 Therasense, Inc. Procede et systeme de communication de donnees dans un systeme de controle et de gestion de glucose en continu
US8112240B2 (en) 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
RU2416393C2 (ru) * 2005-09-01 2011-04-20 Бакстер Интернэшнл Инк. Препаративная форма аргатробана
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
US7920907B2 (en) 2006-06-07 2011-04-05 Abbott Diabetes Care Inc. Analyte monitoring system and method
CA2662853C (fr) * 2006-08-31 2016-07-26 Emisphere Technologies, Inc. Composes et compositions pour la delivrance d'agents actifs
JP5624766B2 (ja) * 2006-09-27 2014-11-12 イーグル・ファーマシューティカルズ・インコーポレーテッド アルコールを含まないアルガトロバン製剤
US7687516B2 (en) * 2006-09-27 2010-03-30 Eagle Pharmaceuticals, Inc. Alcohol free formulation of argatroban
US20100076019A1 (en) * 2006-10-11 2010-03-25 Eagle Pharmaceuticals, Inc. Alcohol free formulation of argatroban
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8732188B2 (en) 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
WO2008135855A2 (fr) 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticules contenant un inhibiteur de la protéine de transfert d'ester de cholestéryle et un polymère non ionisable
US8309129B2 (en) 2007-05-03 2012-11-13 Bend Research, Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US9545384B2 (en) 2007-06-04 2017-01-17 Bend Research, Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glocol succinate
EP2162120B1 (fr) 2007-06-04 2016-05-04 Bend Research, Inc Nanoparticules comportant un polymère cellulosique non ionisable et un copolymère bloc amphiphile non ionisable
WO2009073216A1 (fr) 2007-12-06 2009-06-11 Bend Research, Inc. Nanoparticules comprenant un polymère non ionisable et un copolymère de méthacrylate fonctionnalisé par amine
WO2009073215A1 (fr) 2007-12-06 2009-06-11 Bend Research, Inc. Compositions pharmaceutiques comprenant des nanoparticules et une matière de remise en suspension
US7915290B2 (en) 2008-02-29 2011-03-29 Baxter International Inc. Argatroban formulations and methods for making and using same
US20090221637A1 (en) * 2008-02-29 2009-09-03 Baxter International Inc. Solid-state salt argatroban formulations and methods for producing and using the same
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
WO2010127050A1 (fr) 2009-04-28 2010-11-04 Abbott Diabetes Care Inc. Détection d'erreur dans des données de répétition critiques dans un système de capteur sans fil
WO2010138856A1 (fr) 2009-05-29 2010-12-02 Abbott Diabetes Care Inc. Systèmes d'antenne de dispositif médical comportant des configurations d'antenne externe
US8993331B2 (en) 2009-08-31 2015-03-31 Abbott Diabetes Care Inc. Analyte monitoring system and methods for managing power and noise
US9314195B2 (en) 2009-08-31 2016-04-19 Abbott Diabetes Care Inc. Analyte signal processing device and methods
US9320461B2 (en) 2009-09-29 2016-04-26 Abbott Diabetes Care Inc. Method and apparatus for providing notification function in analyte monitoring systems
CN102366410B (zh) * 2011-09-14 2013-05-29 海南灵康制药有限公司 一种阿加曲班脂质体注射剂
AU2012335830B2 (en) 2011-11-07 2017-05-04 Abbott Diabetes Care Inc. Analyte monitoring device and methods
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
WO2015006679A2 (fr) 2013-07-11 2015-01-15 Aqua Turf International, Inc. Masque de filtration d'air ayant un couvercle frontal ouvrant
DE102014108210A1 (de) 2014-06-11 2015-12-17 Dietrich Gulba Rodentizid
CN114025746B (zh) * 2019-05-10 2023-08-25 福多兹制药公司 抗血栓形成剂的可注射聚合物纳米颗粒组合物及其方法
CN110478471B (zh) * 2019-09-17 2020-04-10 鲁南制药集团股份有限公司 一种阿加曲班注射液及其制备方法
US20230134153A1 (en) 2020-07-03 2023-05-04 Toshiba Mitsubishi-Electric Industrial Systems Corporation Uninterruptible power supply system
EP4070658A1 (fr) 2021-04-06 2022-10-12 BIORoxx GmbH Utilisation de composés anticoagulants comme rodenticides
CN113855635A (zh) * 2021-10-20 2021-12-31 陇南市第一人民医院 一种阿加曲班注射液脂质体及其制备方法

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JPH02129123A (ja) * 1988-11-07 1990-05-17 Mitsubishi Kasei Corp 抗血液凝固剤
CA2091715A1 (fr) * 1992-03-18 1993-09-19 Mitsubishi Kasei Corporation Preparations d'argatroban pour usage ophtalmique
EP0566897A3 (en) * 1992-04-07 1994-07-06 Hoechst Ag The complete gene (cefg) encoding the acetyl-coa: deacetylcephalosporin c acetyltransferase of cephalosporium acremonium, its isolation and use

Also Published As

Publication number Publication date
PL178586B1 (pl) 2000-05-31
IL112527A (en) 1999-04-11
ZA95837B (en) 1996-03-29
JP3027103B2 (ja) 2000-03-27
US5679690A (en) 1997-10-21
CA2141704C (fr) 2001-07-03
ATE179327T1 (de) 1999-05-15
KR950031042A (ko) 1995-12-18
EP0669131B1 (fr) 1999-04-28
JPH07277980A (ja) 1995-10-24
EP0669131A1 (fr) 1995-08-30
CZ27195A3 (en) 1995-09-13
NO307324B1 (no) 2000-03-20
GR3030149T3 (en) 1999-08-31
CN1054743C (zh) 2000-07-26
HU218220B (hu) 2000-06-28
CN1109754A (zh) 1995-10-11
HK1013623A1 (en) 1999-09-03
TW436295B (en) 2001-05-28
ES2132547T3 (es) 1999-08-16
RU95101387A (ru) 1997-02-27
PL307041A1 (en) 1995-08-07
FI950459A (fi) 1995-08-04
NO950377L (no) 1995-08-04
FI950459A0 (fi) 1995-02-02
FR2715566B1 (fr) 1996-03-08
SK12795A3 (en) 1995-08-09
AU1154395A (en) 1995-08-10
DK0669131T3 (da) 1999-11-01
HUT71524A (en) 1995-12-28
RU2136282C1 (ru) 1999-09-10
IL112527A0 (en) 1995-05-26
AU687133B2 (en) 1998-02-19
FR2715566A1 (fr) 1995-08-04
CZ284611B6 (cs) 1999-01-13
DE69509279D1 (de) 1999-06-02
NO950377D0 (no) 1995-02-02
NZ270445A (en) 1995-07-26
KR100257692B1 (ko) 2000-08-01
DE69509279T2 (de) 1999-11-25

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Effective date: 20150202