CA2139284A1 - Automation of Plasma Sequestration - Google Patents

Automation of Plasma Sequestration

Info

Publication number
CA2139284A1
CA2139284A1 CA2139284A CA2139284A CA2139284A1 CA 2139284 A1 CA2139284 A1 CA 2139284A1 CA 2139284 A CA2139284 A CA 2139284A CA 2139284 A CA2139284 A CA 2139284A CA 2139284 A1 CA2139284 A1 CA 2139284A1
Authority
CA
Canada
Prior art keywords
volume
calculated
centrifuge
fill
marker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2139284A
Other languages
French (fr)
Other versions
CA2139284C (en
Inventor
G. Delbert Antwiler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cobe Cardiovascular Inc
Original Assignee
Cobe Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cobe Laboratories Inc filed Critical Cobe Laboratories Inc
Publication of CA2139284A1 publication Critical patent/CA2139284A1/en
Application granted granted Critical
Publication of CA2139284C publication Critical patent/CA2139284C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B13/00—Control arrangements specially designed for centrifuges; Programme control of centrifuges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0429—Red blood cells; Erythrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3306—Optical measuring means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0464—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with hollow or massive core in centrifuge bowl

Abstract

A plasma sequestration system having a volume control system is provided. When a calculated volume of whole blood has been processed, the system switches from a fill to an empty cycle. The termination point is calculated in advance, based on the desired composition of the collected plasma, thus improving process control and product uniformity. The system is automated or partially automated using an optical sensor or marker to monitor the volume of packed red blood cells. When the red cells reach the marker or sensor, a signal is sent to the control system which then calculates the required fill volume. Processing continues until the calculated fill volume is reached, at which time the system automatically stops the collection cycle. The system also provides for two speed operation of the centrifuge as a safeguard against foaming which may result in aerosol formation and blood trauma.
Foaming is reduced by reducing centrifuge speed as the packed red blood cells approach the stationary deflector in the centrifuge bowl.
CA002139284A 1994-01-21 1994-12-29 Automation of plasma sequestration Expired - Fee Related CA2139284C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/185,487 1994-01-21
US08/185,487 US5437598A (en) 1994-01-21 1994-01-21 Automation of plasma sequestration

Publications (2)

Publication Number Publication Date
CA2139284A1 true CA2139284A1 (en) 1995-07-22
CA2139284C CA2139284C (en) 1998-08-11

Family

ID=22681187

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002139284A Expired - Fee Related CA2139284C (en) 1994-01-21 1994-12-29 Automation of plasma sequestration

Country Status (7)

Country Link
US (2) US5437598A (en)
EP (1) EP0664160B1 (en)
JP (1) JP3027795B2 (en)
AT (1) ATE186657T1 (en)
AU (1) AU675746B2 (en)
CA (1) CA2139284C (en)
DE (1) DE69513312T2 (en)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5730883A (en) 1991-12-23 1998-03-24 Baxter International Inc. Blood processing systems and methods using apparent hematocrit as a process control parameter
US6632191B1 (en) 1994-10-13 2003-10-14 Haemonetics Corporation System and method for separating blood components
US7332125B2 (en) * 1994-10-13 2008-02-19 Haemonetics Corporation System and method for processing blood
US5651766A (en) * 1995-06-07 1997-07-29 Transfusion Technologies Corporation Blood collection and separation system
US5733253A (en) * 1994-10-13 1998-03-31 Transfusion Technologies Corporation Fluid separation system
US5733545A (en) * 1995-03-03 1998-03-31 Quantic Biomedical Partners Platelet glue wound sealant
US5704888A (en) * 1995-04-14 1998-01-06 Cobe Laboratories, Inc. Intermittent collection of mononuclear cells in a centrifuge apparatus
US5704889A (en) * 1995-04-14 1998-01-06 Cobe Laboratories, Inc. Spillover collection of sparse components such as mononuclear cells in a centrifuge apparatus
CA2222506C (en) 1995-06-06 2007-07-24 Quantic Biomedical Partners Device and method for concentrating plasma
US6312607B1 (en) 1995-06-07 2001-11-06 Baxter International Inc. Blood processing systems and methods which optically monitor incremental platelet volumes in a plasma constituent
US5676644A (en) * 1995-06-07 1997-10-14 Cobe Laboratories, Inc. Extracorporeal blood processing methods and apparatus
US5958250A (en) 1995-06-07 1999-09-28 Baxter International Inc. Blood processing systems and methods which optically derive the volume of platelets contained in a plasma constituent
US5762791A (en) * 1995-08-09 1998-06-09 Baxter International Inc. Systems for separating high hematocrit red blood cell concentrations
US6527957B1 (en) 1995-08-09 2003-03-04 Baxter International Inc. Methods for separating, collecting and storing red blood cells
US6251284B1 (en) 1995-08-09 2001-06-26 Baxter International Inc. Systems and methods which obtain a uniform targeted volume of concentrated red blood cells in diverse donor populations
US5964724A (en) * 1996-01-31 1999-10-12 Medtronic Electromedics, Inc. Apparatus and method for blood separation
US5637082A (en) * 1996-02-22 1997-06-10 Haemonetics Corporation Adaptive apheresis apparatus
DE19746914C2 (en) * 1996-10-25 1999-07-22 Peter Dr Geigle Centrifugation unit
US5734464A (en) * 1996-11-06 1998-03-31 Cobe Laboratories, Inc. Red blood cell spillover detection technique
US5954971A (en) * 1997-01-07 1999-09-21 Haemonetics Corporation Pumped-filter blood-processing apparatus and methods
AU723430B2 (en) * 1997-01-08 2000-08-24 Vivolution A/S Apparatus and methods for preparing blood or plasma component solutions of known concentration
WO1998043720A1 (en) * 1997-04-03 1998-10-08 Baxter International Inc. Interface detection and control systems and methods
US6200287B1 (en) 1997-09-05 2001-03-13 Gambro, Inc. Extracorporeal blood processing methods and apparatus
US6254784B1 (en) 1997-10-30 2001-07-03 Baxter International Inc. Optical interface detection system for centrifugal blood processing
US6175420B1 (en) 1998-05-20 2001-01-16 Zymequest, Inc. Optical sensors for cell processing systems
CA2346814A1 (en) 1998-10-16 2000-04-27 Mission Medical, Inc. Blood processing system
US6296602B1 (en) 1999-03-17 2001-10-02 Transfusion Technologies Corporation Method for collecting platelets and other blood components from whole blood
JP3817091B2 (en) * 1999-07-02 2006-08-30 テルモ株式会社 Cell number measuring device
ATE523217T1 (en) * 2000-03-09 2011-09-15 Caridianbct Inc EXTRACORPORAL DEVICE FOR BLOOD PROCESSING
US8229675B2 (en) * 2000-03-31 2012-07-24 Global Med Technologies, Inc. Patient information bar and method for tracking and displaying blood products
CN100431637C (en) * 2000-07-07 2008-11-12 汾沃有限公司 Medical system, method and apparatus employing mems
JP4786812B2 (en) * 2001-03-29 2011-10-05 テルモ株式会社 Blood component collection device
US6835316B2 (en) 2001-04-09 2004-12-28 Medtronic, Inc. Clam shell blood reservoir holder with index line
US6890291B2 (en) 2001-06-25 2005-05-10 Mission Medical, Inc. Integrated automatic blood collection and processing unit
JP4832683B2 (en) * 2001-09-19 2011-12-07 テルモ株式会社 Platelet collection device
US6589153B2 (en) * 2001-09-24 2003-07-08 Medtronic, Inc. Blood centrifuge with exterior mounted, self-balancing collection chambers
JP4832686B2 (en) * 2001-09-26 2011-12-07 テルモ株式会社 Platelet collection device
US7211037B2 (en) 2002-03-04 2007-05-01 Therakos, Inc. Apparatus for the continuous separation of biological fluids into components and method of using same
US7479123B2 (en) 2002-03-04 2009-01-20 Therakos, Inc. Method for collecting a desired blood component and performing a photopheresis treatment
AU2003228582A1 (en) 2002-04-19 2003-11-03 Mission Medical, Inc. Integrated automatic blood processing unit
US7992725B2 (en) 2002-05-03 2011-08-09 Biomet Biologics, Llc Buoy suspension fractionation system
US7374678B2 (en) * 2002-05-24 2008-05-20 Biomet Biologics, Inc. Apparatus and method for separating and concentrating fluids containing multiple components
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US20030205538A1 (en) * 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
AU2003249642A1 (en) 2002-05-24 2003-12-12 Biomet Manufacturing Corp. Apparatus and method for separating and concentrating fluids containing multiple components
US20060278588A1 (en) 2002-05-24 2006-12-14 Woodell-May Jennifer E Apparatus and method for separating and concentrating fluids containing multiple components
US7845499B2 (en) 2002-05-24 2010-12-07 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US6982038B2 (en) 2002-06-14 2006-01-03 Medtronic, Inc. Centrifuge system utilizing disposable components and automated processing of blood to collect platelet rich plasma
US20050049539A1 (en) * 2003-09-03 2005-03-03 O'hara Gerald P. Control system for driving fluids through an extracorporeal blood circuit
JP4937904B2 (en) * 2004-05-12 2012-05-23 マックスサイト インコーポレーティッド Method and apparatus associated with a controlled flow electroporation chamber
US7476209B2 (en) * 2004-12-21 2009-01-13 Therakos, Inc. Method and apparatus for collecting a blood component and performing a photopheresis treatment
US7866485B2 (en) 2005-02-07 2011-01-11 Hanuman, Llc Apparatus and method for preparing platelet rich plasma and concentrates thereof
EP2666494B1 (en) * 2005-02-07 2018-01-17 Hanuman LLC Platelet rich plasma concentrate apparatus and method
US7708152B2 (en) * 2005-02-07 2010-05-04 Hanuman Llc Method and apparatus for preparing platelet rich plasma and concentrates thereof
US20060258903A1 (en) * 2005-05-13 2006-11-16 David Stefanchik Method of inserting a feeding tube
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8430813B2 (en) * 2006-05-26 2013-04-30 Depuy Spine, Inc. Illuminated surgical access system including a surgical access device and integrated light emitter
US20080200859A1 (en) * 2007-02-15 2008-08-21 Mehdi Hatamian Apheresis systems & methods
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
EP2146794B1 (en) 2007-04-12 2016-10-19 Biomet Biologics, LLC Buoy suspension fractionation system
KR20100017695A (en) * 2007-05-09 2010-02-16 어드밴스드 테크놀러지 머티리얼즈, 인코포레이티드 Systems and methods for material blending and distribution
EP2567692B1 (en) 2008-02-27 2016-04-06 Biomet Biologics, LLC Use of a device for obtaining interleukin-1 receptor antagonist rich solutions
EP2254991B1 (en) 2008-02-29 2018-08-22 Biomet Manufacturing, LLC A system and process for separating a material
US8628489B2 (en) 2008-04-14 2014-01-14 Haemonetics Corporation Three-line apheresis system and method
US8454548B2 (en) 2008-04-14 2013-06-04 Haemonetics Corporation System and method for plasma reduced platelet collection
US8702637B2 (en) 2008-04-14 2014-04-22 Haemonetics Corporation System and method for optimized apheresis draw and return
US20090274348A1 (en) * 2008-04-30 2009-11-05 Ortho-Clinical Diagnostics, Inc. Immunodiagnostic test apparatus having at least one imager to provide agglutination evaluations during centrifugration cycle
US8012077B2 (en) * 2008-05-23 2011-09-06 Biomet Biologics, Llc Blood separating device
US8187475B2 (en) 2009-03-06 2012-05-29 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US8834402B2 (en) 2009-03-12 2014-09-16 Haemonetics Corporation System and method for the re-anticoagulation of platelet rich plasma
US8313954B2 (en) 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
US9011800B2 (en) 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
WO2012060848A1 (en) 2010-11-05 2012-05-10 Haemonetics Corporation System and method for automated platelet wash
US9302042B2 (en) 2010-12-30 2016-04-05 Haemonetics Corporation System and method for collecting platelets and anticipating plasma return
US11386993B2 (en) 2011-05-18 2022-07-12 Fenwal, Inc. Plasma collection with remote programming
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
CN104602725B (en) 2012-09-04 2017-04-26 汾沃有限公司 Interface detector for blood processing system
US10143725B2 (en) 2013-03-15 2018-12-04 Biomet Biologics, Llc Treatment of pain using protein solutions
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US20140271589A1 (en) 2013-03-15 2014-09-18 Biomet Biologics, Llc Treatment of collagen defects using protein solutions
US10208095B2 (en) 2013-03-15 2019-02-19 Biomet Manufacturing, Llc Methods for making cytokine compositions from tissues using non-centrifugal methods
US9950035B2 (en) 2013-03-15 2018-04-24 Biomet Biologics, Llc Methods and non-immunogenic compositions for treating inflammatory disorders
CN106030260B (en) * 2014-02-24 2019-05-07 费森尤斯卡比德国有限公司 Through retrieving the device and method of the liquid level of blood in blood collection storage cavern for determining autotransfusion system
US9713810B2 (en) 2015-03-30 2017-07-25 Biomet Biologics, Llc Cell washing plunger using centrifugal force
US9757721B2 (en) 2015-05-11 2017-09-12 Biomet Biologics, Llc Cell washing plunger using centrifugal force
US10758652B2 (en) 2017-05-30 2020-09-01 Haemonetics Corporation System and method for collecting plasma
US10792416B2 (en) 2017-05-30 2020-10-06 Haemonetics Corporation System and method for collecting plasma
US10561784B2 (en) 2017-05-31 2020-02-18 Fenwal, Inc. Stationary optical monitoring system for blood processing system
KR102443846B1 (en) 2018-05-21 2022-09-16 펜월, 인크. Systems for optimization of plasma collection volumes
US11412967B2 (en) 2018-05-21 2022-08-16 Fenwal, Inc. Systems and methods for plasma collection
US11898967B2 (en) 2021-02-02 2024-02-13 Fenwal, Inc. Predicting malfunction and failure of centrifuge umbilicus
CN114146827B (en) * 2021-11-26 2024-01-23 南京双威生物医学科技有限公司 One-time centrifugation preparation method of platelet-rich plasma
CN116570789B (en) * 2023-07-13 2023-10-13 四川天府南格尔生物医学有限公司 Plasma collection system and collection method

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3655123A (en) * 1966-08-08 1972-04-11 Us Health Education & Welfare Continuous flow blood separator
US4146172A (en) * 1977-10-18 1979-03-27 Baxter Travenol Laboratories, Inc. Centrifugal liquid processing system
US4151844A (en) * 1977-11-11 1979-05-01 Baxter Travenol Laboratories, Inc. Method and apparatus for separating whole blood into its components and for automatically collecting one component
SE416378B (en) * 1979-03-28 1980-12-22 Johansson A S SET ON SEPARATION OF BLOOD COMPONENTS FROM WHOLE BLOOD APPLICABLE BLOOD PASS SYSTEM FOR EXECUTIVE DEVICE SET
US4464167A (en) * 1981-09-03 1984-08-07 Haemonetics Corporation Pheresis apparatus
US4498983A (en) * 1983-05-26 1985-02-12 Baxter Travenol Laboratories, Inc. Pressure cuff draw mode enhancement system and method for a single needle blood fractionation system
DE3627814A1 (en) * 1986-08-16 1988-02-25 Fresenius Ag DEVICE FOR DETERMINING THE HAEMATOCRIT
DE3632176A1 (en) * 1986-09-22 1988-04-07 Fresenius Ag CONTROL OF A SYSTEM FOR SEPARATING THE COMPONENTS OF BLOOD TAKEN FROM A DONOR "IN VIVO"
US4834890A (en) * 1987-01-30 1989-05-30 Baxter International Inc. Centrifugation pheresis system
US5104526A (en) * 1987-01-30 1992-04-14 Baxter International Inc. Centrifugation system having an interface detection system
US5102407A (en) * 1990-03-13 1992-04-07 Miles Inc. Blood separation system
US5154716A (en) * 1990-11-06 1992-10-13 Miles Inc. Bottom blood bag separation system
DE4036793A1 (en) * 1990-11-19 1992-05-21 Westfalia Separator Ag SPIN DRUM FOR CONCENTRATING SUSPENDED SOLIDS
DE4129516C2 (en) * 1991-09-06 2000-03-09 Fresenius Ag Method and device for separating blood into its components
US5348533A (en) * 1992-08-27 1994-09-20 Haemoentics Corporation Pheresis apparatus

Also Published As

Publication number Publication date
EP0664160A1 (en) 1995-07-26
AU675746B2 (en) 1997-02-13
DE69513312T2 (en) 2000-03-23
JPH07206691A (en) 1995-08-08
US5437598A (en) 1995-08-01
US5505685A (en) 1996-04-09
AU1003695A (en) 1995-08-17
ATE186657T1 (en) 1999-12-15
JP3027795B2 (en) 2000-04-04
CA2139284C (en) 1998-08-11
EP0664160B1 (en) 1999-11-17
DE69513312D1 (en) 1999-12-23

Similar Documents

Publication Publication Date Title
CA2139284A1 (en) Automation of Plasma Sequestration
EP0653062A4 (en) Continuous centrifugation process for the separation of biologic components from heterogeneous cell populations.
AU3671389A (en) Method for separating blood into blood components, and blood components separator unit
AU4373096A (en) Method and device for separating fibrin I from blood plasma
AU591432B2 (en) Process for preparing highly pure cyclic esters
AU5577190A (en) Process for the preparation of ethylene polymers
CA2256354A1 (en) Method for fractionation of a solution by a chromatographic simulated moving bed process
IE812767L (en) Extraction of cloned interferon
AU3199489A (en) Method for removal of heavy metals, especially cadmium, from phosphoric acid containing solutions
AU9117291A (en) Aspiration method for hematology analyzing apparatus
AU562736B2 (en) Process for separating ethylene oxide from aqueous solutions
AU6630096A (en) Process for vacuum refining of molten steel
AU5256590A (en) Method for processing aqueous fermentation broths
AU5980690A (en) Double bubble process for making strong, thin films
AU6902087A (en) Process for bulk polymerizing butadiene
AU590181B2 (en) Method of discharging sewage by vacuum and control apparatus for carrying the method into effect
IL130729A0 (en) Apparatus and methods for preparing blood or plasma component solutions of known concentration
AU6771890A (en) Process for the preparation of vinyl acetate
AU3806889A (en) Process for catalyst aldehyde product separation
AU635953B2 (en) Process for eliminating heavy metals from phosphoric acid
AU633102B2 (en) Process for the preparation of vinyl acetate
AU635363B2 (en) Vacuum pump control apparatus for an evacuating type waste water collecting system
AU3902989A (en) Process for preparing membranes from tetrahalobisphenol polycarbinates
AU6200990A (en) Process for separating off enol ethers from reaction mixtures containing alcohols
FR2641774B3 (en) PROCESS FOR THE PREPARATION OF LITHIUM ZIRCONATE, AND LITHIUM ZIRCONATE AND INTERMEDIATE PRODUCTS PREPARED THEREOF

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed