CA2134539A1 - Procede de selection et/ou d'obtention de sondes capables de detecter de nouvelles regions a nombres variable de repetitions en tandem, sondes pouvant etre ainsi obtenues et leursutilisations - Google Patents
Procede de selection et/ou d'obtention de sondes capables de detecter de nouvelles regions a nombres variable de repetitions en tandem, sondes pouvant etre ainsi obtenues et leursutilisationsInfo
- Publication number
- CA2134539A1 CA2134539A1 CA002134539A CA2134539A CA2134539A1 CA 2134539 A1 CA2134539 A1 CA 2134539A1 CA 002134539 A CA002134539 A CA 002134539A CA 2134539 A CA2134539 A CA 2134539A CA 2134539 A1 CA2134539 A1 CA 2134539A1
- Authority
- CA
- Canada
- Prior art keywords
- probes
- selecting
- obtaining
- detecting new
- new regions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
- C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
Abstract
L'invention a pour objet un procédé de sélection et d'obtention de sondes nucléiques capables de détecter des nouvelles régions à nombre variable de répétitions en tandem (ou VNTR) présentes dans le génome des eucaryotes supérieurs. Sont également objet de l'invention les sondes ainsi obtenues ainsi que leur utilisations. Ce nouveau procédé permet d'obtenir aisément de nouvelles sondes capable de s'apparier à de nouvelles VNTR, en utilisant des fragments d'ADN génomique obtenus après hydrolyse d'ADN à l'aide de certaines enzymes de restriction et sélectionnés d'après leur taille.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9312923A FR2711672B1 (fr) | 1993-10-29 | 1993-10-29 | Procédé de sélection et/ou d'obtention de sondes capables de détecter de nouvelles régions à nombre variable de répétitions en tandem, sondes pouvant être ainsi obtenues et leurs utilisations. |
FR9312923 | 1993-10-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2134539A1 true CA2134539A1 (fr) | 1995-04-30 |
CA2134539C CA2134539C (fr) | 2003-04-22 |
Family
ID=9452348
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002134539A Expired - Fee Related CA2134539C (fr) | 1993-10-29 | 1994-10-27 | Procede de selection et/ou d'obtention de sondes capables de detecter de nouvelles regions a nombres variable de repetitions en tandem, sondes pouvant etre ainsi obtenues et leursutilisations |
Country Status (3)
Country | Link |
---|---|
US (2) | US5573912A (fr) |
CA (1) | CA2134539C (fr) |
FR (1) | FR2711672B1 (fr) |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4800159A (en) * | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
JPH05501946A (ja) * | 1988-02-18 | 1993-04-15 | ユニバーシティ・オブ・ユタ | 可変数タンデム反復座のdnaプローブを使用する遺伝的同定 |
US4963663A (en) * | 1988-12-23 | 1990-10-16 | University Of Utah | Genetic identification employing DNA probes of variable number tandem repeat loci |
US5032501A (en) * | 1989-02-10 | 1991-07-16 | Virginia Mason Research Center | DNA probes to vntr loci |
US5075217A (en) * | 1989-04-21 | 1991-12-24 | Marshfield Clinic | Length polymorphisms in (dC-dA)n ·(dG-dT)n sequences |
US5097024A (en) * | 1989-09-25 | 1992-03-17 | Hodes Marion E | DNA probes for fingerpint analysis without tandem repeats |
US5273878A (en) * | 1990-08-30 | 1993-12-28 | John Groffen | Nucleic acid probes that reveal hypervariable restriction fragment length polymorphisms within the ABR gene |
US5364759B2 (en) * | 1991-01-31 | 1999-07-20 | Baylor College Medicine | Dna typing with short tandem repeat polymorphisms and identification of polymorphic short tandem repeats |
US5427932A (en) * | 1991-04-09 | 1995-06-27 | Reagents Of The University Of California | Repeat sequence chromosome specific nucleic acid probes and methods of preparing and using |
US5378602A (en) * | 1991-05-29 | 1995-01-03 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Highly informative microsatellite repeat polymorphic DNA markers twenty-[seven]six |
FR2680520B1 (fr) * | 1991-08-22 | 1995-09-22 | France Etat Armement | Procede de detection de nouvelles regions hypervariables dans une sequence d'adn, sequences de nucleotides constituant des sondes d'hybridation et leur application biologique. |
-
1993
- 1993-10-29 FR FR9312923A patent/FR2711672B1/fr not_active Expired - Fee Related
-
1994
- 1994-10-27 CA CA002134539A patent/CA2134539C/fr not_active Expired - Fee Related
- 1994-10-31 US US08/331,910 patent/US5573912A/en not_active Expired - Lifetime
-
1996
- 1996-07-31 US US08/690,129 patent/US5716786A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2134539C (fr) | 2003-04-22 |
US5573912A (en) | 1996-11-12 |
FR2711672A1 (fr) | 1995-05-05 |
US5716786A (en) | 1998-02-10 |
FR2711672B1 (fr) | 1995-12-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20131029 |