CA2132293A1 - Medical devices subject to triggered disintegration - Google Patents

Medical devices subject to triggered disintegration

Info

Publication number
CA2132293A1
CA2132293A1 CA002132293A CA2132293A CA2132293A1 CA 2132293 A1 CA2132293 A1 CA 2132293A1 CA 002132293 A CA002132293 A CA 002132293A CA 2132293 A CA2132293 A CA 2132293A CA 2132293 A1 CA2132293 A1 CA 2132293A1
Authority
CA
Canada
Prior art keywords
medical devices
present
ionically crosslinked
crosslinking ion
ionically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002132293A
Other languages
French (fr)
Other versions
CA2132293C (en
Inventor
Gary A. Luzio
Samuel A. Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Scientific Ltd Barbados
Original Assignee
Hercules LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hercules LLC filed Critical Hercules LLC
Publication of CA2132293A1 publication Critical patent/CA2132293A1/en
Application granted granted Critical
Publication of CA2132293C publication Critical patent/CA2132293C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
    • Y10T428/2985—Solid-walled microcapsule from synthetic polymer
    • Y10T428/2987—Addition polymer from unsaturated monomers only

Abstract

The present invention provides medical devices comprised of ionically crosslinked polymer, especially, stents, catheter or cannula components, plugs, and constrictors . The medical devices of the present invention are prepared by treatment of ionically crosslinkable polymer compositions with crosslinking ion compositions to provide ionically crosslinked materials.
An important aspect of the present invention is that these medical devices can be disintegrated in-vivo at a desired time through the exposure of the medical device to a chemical trigger which generally is described as an agent that acts to displace the crosslinking ion in the ionically crosslinked material through binding or simple replacement with a non-crosslinking ion.
CA002132293A 1993-09-29 1994-09-16 Medical devices subject to triggered disintegration Expired - Fee Related CA2132293C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US128,952 1987-12-04
US08/128,952 US5531716A (en) 1993-09-29 1993-09-29 Medical devices subject to triggered disintegration

Publications (2)

Publication Number Publication Date
CA2132293A1 true CA2132293A1 (en) 1995-03-30
CA2132293C CA2132293C (en) 2009-04-07

Family

ID=22437777

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002132293A Expired - Fee Related CA2132293C (en) 1993-09-29 1994-09-16 Medical devices subject to triggered disintegration

Country Status (13)

Country Link
US (5) US5531716A (en)
EP (1) EP0645150B1 (en)
JP (1) JP3703155B2 (en)
KR (1) KR950007801A (en)
CN (1) CN1114177A (en)
AT (1) ATE209511T1 (en)
AU (1) AU685152B2 (en)
BR (1) BR9403911A (en)
CA (1) CA2132293C (en)
DE (1) DE69429227T2 (en)
DK (1) DK0645150T3 (en)
PL (1) PL177431B1 (en)
RU (1) RU2138297C1 (en)

Families Citing this family (196)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5531716A (en) * 1993-09-29 1996-07-02 Hercules Incorporated Medical devices subject to triggered disintegration
US6361526B1 (en) * 1993-11-01 2002-03-26 Medtronic Xomed, Inc. Antimicrobial tympanostomy tube
US5505713A (en) * 1994-04-01 1996-04-09 Minimed Inc. Indwelling catheter with stable enzyme coating
US5931165A (en) * 1994-09-06 1999-08-03 Fusion Medical Technologies, Inc. Films having improved characteristics and methods for their preparation and use
US5531735A (en) * 1994-09-27 1996-07-02 Hercules Incorporated Medical devices containing triggerable disintegration agents
US6214331B1 (en) * 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
US7611533B2 (en) * 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
US6774278B1 (en) * 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
US7867275B2 (en) * 1995-06-07 2011-01-11 Cook Incorporated Coated implantable medical device method
US20070203520A1 (en) * 1995-06-07 2007-08-30 Dennis Griffin Endovascular filter
US7846202B2 (en) * 1995-06-07 2010-12-07 Cook Incorporated Coated implantable medical device
US7896914B2 (en) * 1995-06-07 2011-03-01 Cook Incorporated Coated implantable medical device
US7550005B2 (en) 1995-06-07 2009-06-23 Cook Incorporated Coated implantable medical device
US5702682A (en) * 1995-12-01 1997-12-30 Hercules Incorporated Methods for preparing radiopaque medical devices
US5718862A (en) * 1996-04-24 1998-02-17 Hercules Incorporated Secondary shaping of ionically crosslinked polymer compositions for medical devices
US5684051A (en) * 1996-04-24 1997-11-04 Hercules Incorporated Medical devices with improved elastic response
AU737078C (en) 1996-05-24 2002-05-02 Angiotech Pharmaceuticals, Inc. Compositions and methods for treating or preventing diseases of body passageways
EP0909148A1 (en) * 1996-05-31 1999-04-21 The University Of Western Ontario Expansible bioprosthetic valve stent
US5791352A (en) * 1996-06-19 1998-08-11 Fusion Medical Technologies, Inc. Methods and compositions for inhibiting tissue adhesion
US6368356B1 (en) 1996-07-11 2002-04-09 Scimed Life Systems, Inc. Medical devices comprising hydrogel polymers having improved mechanical properties
US5820918A (en) * 1996-07-11 1998-10-13 Hercules Incorporated Medical devices containing in-situ generated medical compounds
US6060534A (en) 1996-07-11 2000-05-09 Scimed Life Systems, Inc. Medical devices comprising ionically and non-ionically crosslinked polymer hydrogels having improved mechanical properties
US6530951B1 (en) * 1996-10-24 2003-03-11 Cook Incorporated Silver implantable medical device
EP0948784B1 (en) * 1996-12-04 2002-03-20 Erbe Elektromedizin GmbH Artifical tissue
EP0997057B1 (en) * 1997-07-18 2006-12-13 Resound Corporation Behind the ear hearing aid system
EP1763284B1 (en) * 1997-07-18 2018-06-13 Resound Corporation Behind the ear hearing system
US6186985B1 (en) 1997-10-03 2001-02-13 Boston Scientific Corporation Gastro-intestinal tube with dissolvable support bolster
US6293960B1 (en) 1998-05-22 2001-09-25 Micrus Corporation Catheter with shape memory polymer distal tip for deployment of therapeutic devices
US7314477B1 (en) 1998-09-25 2008-01-01 C.R. Bard Inc. Removable embolus blood clot filter and filter delivery unit
US6371904B1 (en) 1998-12-24 2002-04-16 Vivant Medical, Inc. Subcutaneous cavity marking device and method
US6356782B1 (en) * 1998-12-24 2002-03-12 Vivant Medical, Inc. Subcutaneous cavity marking device and method
US9669113B1 (en) 1998-12-24 2017-06-06 Devicor Medical Products, Inc. Device and method for safe location and marking of a biopsy cavity
US6165140A (en) 1998-12-28 2000-12-26 Micrus Corporation Composite guidewire
DK173680B1 (en) * 1999-02-10 2001-06-11 Coloplast As ostomy Prop
AU3503700A (en) * 1999-02-25 2000-09-14 Scimed Life Systems, Inc. Medical devices comprising hydrogel polymers having improved mechanical properties
US6575930B1 (en) * 1999-03-12 2003-06-10 Medrad, Inc. Agitation devices and dispensing systems incorporating such agitation devices
US6231589B1 (en) 1999-03-22 2001-05-15 Microvena Corporation Body vessel filter
US6352531B1 (en) 1999-03-24 2002-03-05 Micrus Corporation Variable stiffness optical fiber shaft
US6887235B2 (en) 1999-03-24 2005-05-03 Micrus Corporation Variable stiffness heating catheter
DK1229940T3 (en) 1999-11-15 2014-08-18 Piramal Healthcare Canada Ltd TEMPERATURE CONTROL AND PH-DEPENDENT SELF-GELING, Aqueous BIOPOLYMER SOLUTION
AU1848601A (en) * 1999-12-09 2001-06-18 Bio Syntech Canada Inc Mineral-polymer hybrid composition
US20030158302A1 (en) * 1999-12-09 2003-08-21 Cyric Chaput Mineral-polymer hybrid composition
US6592566B2 (en) 2000-02-03 2003-07-15 Arizona Board Of Regents Method for forming an endovascular occlusion
SG149679A1 (en) 2000-06-29 2009-02-27 Biosyntech Canada Inc Composition and method for the repair and regeneration of cartilage and other tissues
US6607553B1 (en) 2000-11-17 2003-08-19 B. Braun Medical, Inc. Method for deploying a thermo-mechanically expandable stent
US6913765B2 (en) * 2001-03-21 2005-07-05 Scimed Life Systems, Inc. Controlling resorption of bioresorbable medical implant material
DE10115740A1 (en) 2001-03-26 2002-10-02 Ulrich Speck Preparation for restenosis prophylaxis
WO2002103004A1 (en) * 2001-06-15 2002-12-27 The Children's Hospital Of Philadelphia Surface modification for improving biocompatibility
US20040143180A1 (en) * 2001-11-27 2004-07-22 Sheng-Ping Zhong Medical devices visible under magnetic resonance imaging
US20030100830A1 (en) 2001-11-27 2003-05-29 Sheng-Ping Zhong Implantable or insertable medical devices visible under magnetic resonance imaging
US20030153971A1 (en) * 2002-02-14 2003-08-14 Chandru Chandrasekaran Metal reinforced biodegradable intraluminal stents
US20030153972A1 (en) * 2002-02-14 2003-08-14 Michael Helmus Biodegradable implantable or insertable medical devices with controlled change of physical properties leading to biomechanical compatibility
US9204956B2 (en) 2002-02-20 2015-12-08 C. R. Bard, Inc. IVC filter with translating hooks
US8328877B2 (en) 2002-03-19 2012-12-11 Boston Scientific Scimed, Inc. Stent retention element and related methods
US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
GB0210216D0 (en) * 2002-05-03 2002-06-12 First Water Ltd Ionically crosslinked alginate hydrogels, process for their manufacture and their use in medical devices
EP1511522B1 (en) 2002-06-12 2011-08-10 Boston Scientific Limited Bulking agents
EP2851097A3 (en) * 2002-07-12 2015-06-10 Cook Medical Technologies LLC Drug-coated angioplasty balloons
US7842377B2 (en) 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US7338433B2 (en) 2002-08-13 2008-03-04 Allergan, Inc. Remotely adjustable gastric banding method
EP2181655B1 (en) 2002-08-28 2016-12-07 Apollo Endosurgery, Inc. Fatigue-restistant gastric banding device
US8012454B2 (en) 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
DE10243132B4 (en) 2002-09-17 2006-09-14 Biocer Entwicklungs Gmbh Anti-infective, biocompatible titanium oxide coatings for implants and methods of making them
DE10244847A1 (en) 2002-09-20 2004-04-01 Ulrich Prof. Dr. Speck Medical device for drug delivery
WO2004029581A2 (en) * 2002-09-26 2004-04-08 The Children's Hospital Of Philadelphia Method of determining surface binding capacity
US7883490B2 (en) 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
US6992127B2 (en) 2002-11-25 2006-01-31 Ast Products, Inc. Polymeric coatings containing a pH buffer agent
US8709038B2 (en) * 2002-12-20 2014-04-29 Boston Scientific Scimed, Inc. Puncture hole sealing device
WO2004069169A2 (en) * 2003-01-31 2004-08-19 Scimed Life Systems, Inc. Localized drug delivery using drug-loaded nanocapsules and implantable device coated with the same
FR2861734B1 (en) 2003-04-10 2006-04-14 Corneal Ind CROSSLINKING OF LOW AND HIGH MOLECULAR MASS POLYSACCHARIDES; PREPARATION OF INJECTABLE SINGLE PHASE HYDROGELS; POLYSACCHARIDES AND HYDROGELS OBTAINED
US6923996B2 (en) * 2003-05-06 2005-08-02 Scimed Life Systems, Inc. Processes for producing polymer coatings for release of therapeutic agent
GB0310858D0 (en) * 2003-05-12 2003-06-18 Univ Cambridge Tech Polymer transistor
KR101172526B1 (en) * 2003-05-12 2012-08-13 캠브리지 엔터프라이즈 리미티드 Manufacture of a polymer device
US7364585B2 (en) * 2003-08-11 2008-04-29 Boston Scientific Scimed, Inc. Medical devices comprising drug-loaded capsules for localized drug delivery
US7976823B2 (en) 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
US20050143678A1 (en) 2003-10-14 2005-06-30 Pluromed, Inc. Confinement of kidney-stone fragments during lithotripsy
US7294123B2 (en) * 2003-12-17 2007-11-13 Corris Neurovascular, Inc. Activatable bioactive vascular occlusive device and method of use
DE602004029928D1 (en) * 2003-12-23 2010-12-16 Fmc Biopolymer As USE OF ALGINATE MATRICES FOR CONTROLLING CELL GROWTH
EP1706044B1 (en) 2004-01-23 2011-10-05 Allergan, Inc. Releasably-securable one-piece adjustable gastric band
US7736671B2 (en) 2004-03-02 2010-06-15 Boston Scientific Scimed, Inc. Embolization
US20050220882A1 (en) * 2004-03-04 2005-10-06 Wilson Pritchard Materials for medical implants and occlusive devices
US7811299B2 (en) 2004-03-08 2010-10-12 Allergan, Inc. Closure system for tubular organs
WO2005094257A2 (en) 2004-03-18 2005-10-13 Inamed Medical Products Corporation Apparatus and method for volume adjustment of intragastric balloons
US8173176B2 (en) 2004-03-30 2012-05-08 Boston Scientific Scimed, Inc. Embolization
US7311861B2 (en) 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
US7704267B2 (en) 2004-08-04 2010-04-27 C. R. Bard, Inc. Non-entangling vena cava filter
CA2583373C (en) * 2004-10-12 2013-09-03 Fmc Biopolymer As Self-gelling alginate systems and uses thereof
US7794473B2 (en) 2004-11-12 2010-09-14 C.R. Bard, Inc. Filter delivery system
US8425550B2 (en) 2004-12-01 2013-04-23 Boston Scientific Scimed, Inc. Embolic coils
US8267954B2 (en) 2005-02-04 2012-09-18 C. R. Bard, Inc. Vascular filter with sensing capability
US7727555B2 (en) 2005-03-02 2010-06-01 Boston Scientific Scimed, Inc. Particles
US7858183B2 (en) 2005-03-02 2010-12-28 Boston Scientific Scimed, Inc. Particles
US8251888B2 (en) * 2005-04-13 2012-08-28 Mitchell Steven Roslin Artificial gastric valve
EP2614796B1 (en) 2005-04-25 2020-04-08 Covidien LP Controlled fracture connections for stents
US7963287B2 (en) 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
CN101237887A (en) 2005-05-02 2008-08-06 普拉罗美德公司 Non-lithotripsic kidney-stone therapy
CA2946470C (en) 2005-05-12 2019-02-19 C.R. Bard Inc. Removable embolus blood clot filter
US9463426B2 (en) 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
JP4851522B2 (en) 2005-08-09 2012-01-11 シー・アール・バード・インコーポレーテッド Insertion type thrombus filter and delivery system
US8007509B2 (en) 2005-10-12 2011-08-30 Boston Scientific Scimed, Inc. Coil assemblies, components and methods
EP1948810A4 (en) * 2005-11-04 2010-06-30 Biosyntech Canada Inc Composition and method for efficient delivery of nucleic acids to cells using chitosan
JP2009519731A (en) 2005-11-18 2009-05-21 シー・アール・バード・インコーポレイテツド Vena cava filter with filament
US8101197B2 (en) 2005-12-19 2012-01-24 Stryker Corporation Forming coils
US8152839B2 (en) 2005-12-19 2012-04-10 Boston Scientific Scimed, Inc. Embolic coils
US7947368B2 (en) 2005-12-21 2011-05-24 Boston Scientific Scimed, Inc. Block copolymer particles
US7798954B2 (en) 2006-01-04 2010-09-21 Allergan, Inc. Hydraulic gastric band with collapsible reservoir
US8043206B2 (en) 2006-01-04 2011-10-25 Allergan, Inc. Self-regulating gastric band with pressure data processing
US20070191878A1 (en) * 2006-01-20 2007-08-16 Segner Garland L Body vessel filter
US8828077B2 (en) * 2006-03-15 2014-09-09 Medinol Ltd. Flat process of preparing drug eluting stents
US10188496B2 (en) 2006-05-02 2019-01-29 C. R. Bard, Inc. Vena cava filter formed from a sheet
WO2007143602A2 (en) 2006-06-05 2007-12-13 C.R. Bard Inc. Embolus blood clot filter utilizable with a single delivery system or a single retrieval system in one of a femoral or jugular access
EP2046288B1 (en) * 2006-07-14 2013-07-03 FMC Biopolymer AS Hydrogels containing low molecular weight alginates and biostructures made therefrom
EP2090314A4 (en) * 2006-10-26 2010-01-13 Senju Pharma Co Ophthalmic aqeous liquid preparation
US8414927B2 (en) 2006-11-03 2013-04-09 Boston Scientific Scimed, Inc. Cross-linked polymer particles
JP2010522023A (en) * 2007-03-20 2010-07-01 ボストン サイエンティフィック サイムド，インコーポレイテッド Urological medical device for releasing beneficial therapeutics to the prostate
EP2136854A2 (en) * 2007-03-20 2009-12-30 Boston Scientific Scimed, Inc. Urological medical devices for release of therapeutic agents
US20080243234A1 (en) * 2007-03-27 2008-10-02 Medtronic Vascular, Inc. Magnesium Alloy Stent
WO2008147867A2 (en) * 2007-05-23 2008-12-04 Allergan, Inc. Cross-linked collagen and uses thereof
US20100172953A1 (en) * 2007-06-13 2010-07-08 Fmc Corporation Biopolymer Based Implantable Degradable Devices
US20110077737A1 (en) * 2007-07-30 2011-03-31 Allergan, Inc. Tunably Crosslinked Polysaccharide Compositions
US8318695B2 (en) * 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
KR20100063744A (en) * 2007-08-28 2010-06-11 에프엠씨 코포레이션 Delayed self-gelling alginate systems and uses thereof
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
DE102007050839A1 (en) * 2007-10-24 2009-04-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Carbohydrate-based additives with adhesive effect for aqueous fire and fire protection agents, their preparation and use
KR101577471B1 (en) 2007-11-16 2015-12-14 알러간, 인코포레이티드 Compositions and methods for treating purpura
US20090143348A1 (en) * 2007-11-30 2009-06-04 Ahmet Tezel Polysaccharide gel compositions and methods for sustained delivery of drugs
US8394784B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
US8394782B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US8241657B2 (en) 2007-12-04 2012-08-14 Boston Scientific Scimed, Inc. Biodisintegrable medical devices
WO2009108760A2 (en) 2008-02-26 2009-09-03 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
US20090263458A1 (en) * 2008-04-21 2009-10-22 Lasse Daniel Efskind Material for surgical use in traumatology
WO2009132229A2 (en) 2008-04-24 2009-10-29 Medtronic, Inc. Cold ionizing radiation sterilization
AU2009240513B2 (en) 2008-04-24 2015-03-26 Medtronic, Inc. Chitosan-containing protective composition
JP5833919B2 (en) * 2008-04-24 2015-12-16 メドトロニック，インコーポレイテッド Protective gel based on chitosan and oxidized polysaccharide
EP2291524A2 (en) 2008-04-24 2011-03-09 Medtronic, Inc Rehydratable thiolated polysaccharide particles and sponge
US8450475B2 (en) 2008-08-04 2013-05-28 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
JP5722217B2 (en) 2008-09-02 2015-05-20 アラーガン・ホールディングス・フランス・ソシエテ・パール・アクシオン・サンプリフィエＡｌｌｅｒｇａｎ Ｈｏｌｄｉｎｇｓ Ｆｒａｎｃｅ Ｓ．Ａ．Ｓ． Yarn of hyaluronic acid and / or its derivative, method for its preparation and use thereof
GB0816365D0 (en) * 2008-09-08 2008-10-15 Univ Belfast Polymeric material
US20100305397A1 (en) * 2008-10-06 2010-12-02 Allergan Medical Sarl Hydraulic-mechanical gastric band
WO2010042493A1 (en) 2008-10-06 2010-04-15 Allergan, Inc. Mechanical gastric band with cushions
US20100185049A1 (en) 2008-10-22 2010-07-22 Allergan, Inc. Dome and screw valves for remotely adjustable gastric banding systems
WO2011014703A1 (en) 2009-07-29 2011-02-03 C.R. Bard, Inc. Tubular filter
EP2498764B1 (en) 2009-11-09 2017-09-06 Spotlight Technology Partners LLC Fragmented hydrogels
CA2780294C (en) 2009-11-09 2018-01-16 Spotlight Technology Partners Llc Polysaccharide based hydrogels
US10240419B2 (en) 2009-12-08 2019-03-26 Baker Hughes, A Ge Company, Llc Downhole flow inhibition tool and method of unplugging a seat
EP2338477A1 (en) 2009-12-15 2011-06-29 bene-Arzneimittel GmbH Suppository comprising pantoprazole
US20110171286A1 (en) * 2010-01-13 2011-07-14 Allergan, Inc. Hyaluronic acid compositions for dermatological use
US20110171311A1 (en) * 2010-01-13 2011-07-14 Allergan Industrie, Sas Stable hydrogel compositions including additives
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US8758221B2 (en) 2010-02-24 2014-06-24 Apollo Endosurgery, Inc. Source reservoir with potential energy for remotely adjustable gastric banding system
US8840541B2 (en) * 2010-02-25 2014-09-23 Apollo Endosurgery, Inc. Pressure sensing gastric banding system
RU2440808C2 (en) * 2010-02-27 2012-01-27 Учреждение Российской академии наук Институт органического синтеза им. И.Я. Постовского Уральского отделения РАН Adhesive composition for detachable dentures
WO2011110894A2 (en) * 2010-03-12 2011-09-15 Allergan Industrie Sas Fluid composition for improving skin conditions
HUE043344T2 (en) 2010-03-22 2019-08-28 Allergan Inc Cross-linked hydrogels for soft tissue augmentation
AR081808A1 (en) * 2010-03-26 2012-10-24 Philip Morris Prod PROCEDURE TO PRODUCE A CONTINUOUS STRUCTURE OF AN ENCAPSULATED MATERIAL
US20110270024A1 (en) 2010-04-29 2011-11-03 Allergan, Inc. Self-adjusting gastric band having various compliant components
US9044298B2 (en) 2010-04-29 2015-06-02 Apollo Endosurgery, Inc. Self-adjusting gastric band
US9028394B2 (en) 2010-04-29 2015-05-12 Apollo Endosurgery, Inc. Self-adjusting mechanical gastric band
US20110270025A1 (en) 2010-04-30 2011-11-03 Allergan, Inc. Remotely powered remotely adjustable gastric band system
US8517915B2 (en) 2010-06-10 2013-08-27 Allergan, Inc. Remotely adjustable gastric banding system
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US20120059216A1 (en) 2010-09-07 2012-03-08 Allergan, Inc. Remotely adjustable gastric banding system
US9095558B2 (en) 2010-10-08 2015-08-04 Board Of Regents, The University Of Texas System Anti-adhesive barrier membrane using alginate and hyaluronic acid for biomedical applications
WO2012048283A1 (en) 2010-10-08 2012-04-12 Board Of Regents, The University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
US8961393B2 (en) 2010-11-15 2015-02-24 Apollo Endosurgery, Inc. Gastric band devices and drive systems
CA3133676A1 (en) 2011-06-03 2012-12-06 Allergan Industrie, Sas Dermal filler compositions including antioxidants
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
WO2012171540A1 (en) 2011-06-15 2012-12-20 Bene-Arzneimittel Gmbh Suppository comprising pantoprazole comprised in pellets with a cellulose core
US9707739B2 (en) 2011-07-22 2017-07-18 Baker Hughes Incorporated Intermetallic metallic composite, method of manufacture thereof and articles comprising the same
US9033055B2 (en) 2011-08-17 2015-05-19 Baker Hughes Incorporated Selectively degradable passage restriction and method
US9090956B2 (en) 2011-08-30 2015-07-28 Baker Hughes Incorporated Aluminum alloy powder metal compact
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US8876694B2 (en) 2011-12-07 2014-11-04 Apollo Endosurgery, Inc. Tube connector with a guiding tip
US8961394B2 (en) 2011-12-20 2015-02-24 Apollo Endosurgery, Inc. Self-sealing fluid joint for use with a gastric band
US9010416B2 (en) 2012-01-25 2015-04-21 Baker Hughes Incorporated Tubular anchoring system and a seat for use in the same
CA2894658C (en) 2012-12-11 2017-07-04 Board Of Regents, The University Of Texas System Hydrogel membrane for adhesion prevention
US11565027B2 (en) 2012-12-11 2023-01-31 Board Of Regents, The University Of Texas System Hydrogel membrane for adhesion prevention
EP2968825A4 (en) 2013-03-15 2016-09-07 Childrens Medical Center Gas-filled stabilized particles and methods of use
CA2921952C (en) * 2013-08-21 2022-12-13 Children's National Medical Center Dissolvable on-command implant
US9816339B2 (en) 2013-09-03 2017-11-14 Baker Hughes, A Ge Company, Llc Plug reception assembly and method of reducing restriction in a borehole
US9192692B2 (en) 2013-10-24 2015-11-24 Medtronic Xomed, Inc. Chitosan stenting paste
US9192574B2 (en) 2013-10-24 2015-11-24 Medtronic Xomed, Inc. Chitosan paste wound dressing
US11167343B2 (en) 2014-02-21 2021-11-09 Terves, Llc Galvanically-active in situ formed particles for controlled rate dissolving tools
CA2936851A1 (en) 2014-02-21 2015-08-27 Terves, Inc. Fluid activated disintegrating metal system
WO2016051219A1 (en) 2014-09-30 2016-04-07 Allergan Industrie, Sas Stable hydrogel compositions including additives
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
WO2018079812A1 (en) * 2016-10-31 2018-05-03 キユーピー株式会社 Gel composition and method for producing same
CA3012511A1 (en) 2017-07-27 2019-01-27 Terves Inc. Degradable metal matrix composite
WO2022271985A1 (en) * 2021-06-24 2022-12-29 Rvo 2.0 Inc, D/B/A Optics Medical Catheters comprising a hydrogel polymer

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2485512A (en) * 1941-10-21 1949-10-18 Alginate Ind Ltd Manufacture of transparent alginic films
GB579004A (en) * 1943-11-12 1946-07-19 Ernest Gordon Greville Improved surgical sutures and like surgical material and the manufacture thereof
GB674755A (en) * 1949-08-04 1952-07-02 Courtaulds Ltd Improvements in and relating to the production of artificial protein fibres
US2712672A (en) * 1952-01-28 1955-07-12 Calcagno Luigi Process for preparing proteic sponges
US2847713A (en) * 1955-05-13 1958-08-19 Weingand Richard Process for producing synthetic sausage skins and other laminar structures from alginates
US2897547A (en) * 1955-05-27 1959-08-04 Weingand Richard Process for producing synthetic sausage casing from alginates or alginic acid
US3271496A (en) * 1964-01-27 1966-09-06 Amicon Corp Method of shaping polyelectrolyte polymer
US4137921A (en) * 1977-06-24 1979-02-06 Ethicon, Inc. Addition copolymers of lactide and glycolide and method of preparation
US4339295A (en) * 1978-12-20 1982-07-13 The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services Hydrogel adhesives and sandwiches or laminates using microwave energy
US4286341A (en) * 1979-04-16 1981-09-01 Iowa State University Research Foundation, Inc. Vascular prosthesis and method of making the same
JPS5714640A (en) * 1980-07-02 1982-01-25 Toray Ind Inc Separating membrane of methyl methacrylate type
US4539234A (en) * 1981-05-27 1985-09-03 Unitika Ltd. Urethral catheter capable of preventing urinary tract infection and process for producing the same
US4613517A (en) * 1983-04-27 1986-09-23 Becton, Dickinson And Company Heparinization of plasma treated surfaces
CA1238043A (en) * 1983-12-15 1988-06-14 Endre A. Balazs Water insoluble preparations of hyaluronic acid and processes therefor
FR2559666B1 (en) * 1984-02-21 1986-08-08 Tech Cuir Centre PROCESS FOR THE MANUFACTURE OF COLLAGEN TUBES, ESPECIALLY LOW-DIAMETER TUBES, AND APPLICATION OF THE TUBES OBTAINED IN THE FIELD OF VASCULAR PROSTHESES AND NERVOUS SUTURES
US4716224A (en) * 1984-05-04 1987-12-29 Seikagaku Kogyo Co. Ltd. Crosslinked hyaluronic acid and its use
US4650488A (en) * 1984-05-16 1987-03-17 Richards Medical Company Biodegradable prosthetic device
SE442820B (en) * 1984-06-08 1986-02-03 Pharmacia Ab GEL OF THE CROSS-BOND HYALURONIC ACID FOR USE AS A GLASS BODY SUBSTITUTE
US4863907A (en) * 1984-06-29 1989-09-05 Seikagaku Kogyo Co., Ltd. Crosslinked glycosaminoglycans and their use
US4801475A (en) * 1984-08-23 1989-01-31 Gregory Halpern Method of hydrophilic coating of plastics
US4582865A (en) * 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US4605691A (en) * 1984-12-06 1986-08-12 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US5128326A (en) * 1984-12-06 1992-07-07 Biomatrix, Inc. Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same
US4636524A (en) * 1984-12-06 1987-01-13 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US4851521A (en) * 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
US5202431A (en) * 1985-07-08 1993-04-13 Fidia, S.P.A. Partial esters of hyaluronic acid
JPS6233855A (en) * 1985-07-31 1987-02-13 株式会社　君津化学研究所 Alginic acid nonwoven fabric and its production
US4902295A (en) * 1985-08-26 1990-02-20 Hana Biologics, Inc. Transplantable artificial tissue
AU589438B2 (en) * 1985-08-26 1989-10-12 Hana Biologics, Inc. Transplantable artificial tissue and process
US4997443A (en) * 1985-08-26 1991-03-05 Hana Biologics, Inc. Transplantable artificial tissue and process
SE8504501D0 (en) * 1985-09-30 1985-09-30 Astra Meditec Ab METHOD OF FORMING AN IMPROVED HYDROPHILIC COATING ON A POLYMER SURFACE
US4838876A (en) * 1986-04-29 1989-06-13 The Kendall Company Silicone rubber catheter having improved surface morphology
IT1198449B (en) * 1986-10-13 1988-12-21 F I D I Farmaceutici Italiani ESTERS OF POLYVALENT ALCOHOLS OF HYALURONIC ACID
JPH0696023B2 (en) * 1986-11-10 1994-11-30 宇部日東化成株式会社 Artificial blood vessel and method for producing the same
GB8729977D0 (en) * 1987-12-23 1988-02-03 Bard Ltd Catheter
US4888016A (en) * 1988-02-10 1989-12-19 Langerman David W "Spare parts" for use in ophthalmic surgical procedures
US5061738A (en) * 1988-04-18 1991-10-29 Becton, Dickinson And Company Blood compatible, lubricious article and composition and method therefor
IT1219587B (en) * 1988-05-13 1990-05-18 Fidia Farmaceutici SELF-CROSS-LINKED CARBOXYLY POLYSACCHARIDES
US5085629A (en) * 1988-10-06 1992-02-04 Medical Engineering Corporation Biodegradable stent
US5089606A (en) * 1989-01-24 1992-02-18 Minnesota Mining And Manufacturing Company Water-insoluble polysaccharide hydrogel foam for medical applications
US5057606A (en) * 1989-01-24 1991-10-15 Minnesota Mining And Manufacturing Company Form-in-place polysaccharide gels
HU203372B (en) * 1989-02-24 1991-07-29 Richter Gedeon Vegyeszet Process for producing hyaluronic associates and pharmaceutical compositions and cosmetics comprising such active ingredient
US5049138A (en) * 1989-11-13 1991-09-17 Boston Scientific Corporation Catheter with dissolvable tip
DE69112260T2 (en) * 1990-04-23 1996-04-11 Monsanto Co Gellan rubber fibers.
US5077352A (en) * 1990-04-23 1991-12-31 C. R. Bard, Inc. Flexible lubricious organic coatings
US5149543A (en) * 1990-10-05 1992-09-22 Massachusetts Institute Of Technology Ionically cross-linked polymeric microcapsules
JP2777279B2 (en) * 1990-10-08 1998-07-16 工業技術院長 Wound dressing and method for producing the same
IT1247157B (en) * 1991-02-11 1994-12-12 Fidia Spa BIODEGRADABLE AND BIOABSORBABLE GUIDE CHANNELS TO BE USED FOR NERVE REGENERATION.
GR920100122A (en) * 1991-04-05 1993-03-16 Ethicon Inc Ionically crosslinked carboxyl-containing polysaccharides for adhension prevention.
US5334640A (en) * 1992-04-08 1994-08-02 Clover Consolidated, Ltd. Ionically covalently crosslinked and crosslinkable biocompatible encapsulation compositions and methods
US5306764A (en) * 1992-09-03 1994-04-26 China Technical Consultants Inc. Water dispersible polyurethane and process for preparation thereof
US5531716A (en) * 1993-09-29 1996-07-02 Hercules Incorporated Medical devices subject to triggered disintegration

Also Published As

Publication number Publication date
US6096018A (en) 2000-08-01
DE69429227D1 (en) 2002-01-10
CA2132293C (en) 2009-04-07
JP3703155B2 (en) 2005-10-05
EP0645150B1 (en) 2001-11-28
BR9403911A (en) 1995-05-30
US6126645A (en) 2000-10-03
KR950007801A (en) 1995-04-15
AU685152B2 (en) 1998-01-15
AU7429694A (en) 1995-04-13
RU94034125A (en) 1996-07-10
US5531716A (en) 1996-07-02
PL305241A1 (en) 1995-04-03
PL177431B1 (en) 1999-11-30
US5820608A (en) 1998-10-13
CN1114177A (en) 1996-01-03
EP0645150A1 (en) 1995-03-29
ATE209511T1 (en) 2001-12-15
DE69429227T2 (en) 2002-07-25
DK0645150T3 (en) 2002-03-18
US5650116A (en) 1997-07-22
RU2138297C1 (en) 1999-09-27
JPH07163655A (en) 1995-06-27

Similar Documents

Publication Publication Date Title
CA2132293A1 (en) Medical devices subject to triggered disintegration
CA1145082A (en) Covering material
CA2158689A1 (en) Medical devices containing triggerable disintegration agents
WO1996013286A3 (en) Modulation of cell proliferation and wound healing
CA2290743A1 (en) Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering
GR1002807B (en) Device for topical treatment of acne and method of manufacture.
DE782855T1 (en) ANTI-INFLAMMATIONAL ACTIVE SUBSTANCES
CA2090718A1 (en) Miniaturized low power x-ray source
CA2216696A1 (en) Polysaccharide-bound nitric oxide-nucleophile adducts
EP2407135A3 (en) Absorbent structures of chemically treated cellulose fibers
NZ597106A (en) Ophthalmic compositions comprising carnitine and methods for treating eyes
CA2265708A1 (en) Lipoxin compounds and their use in treating cell proliferative disorders
CA2260750A1 (en) Methods for providing safe local anesthesia
JPS5581649A (en) Polymer composition for medical treatment and its preparation
AU6041880A (en) Germicidal and healing treatment of tissue
AU1756597A (en) Medical syringe and self-retracting needle apparatus
WO2002017880A3 (en) Nitric oxide-producing hydrogel materials
CA2178458A1 (en) Stable complexes of crosslinked polyvinylpyrrolidone and iodine and method of making the same
IL107153A (en) Pharmaceutical compositions for preventing insulin-dependent diabetes mellitus comprising IL10 and method for their manufacture
MX9504023A (en) Transdermally active pharmaceutical composition containing 5-aminolaevulinic acid.
CA2106105A1 (en) Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
WO1995016435A3 (en) Improved intraocular irrigating solution containing non-steroidal antiinflammatory agent
CA2158173A1 (en) Method of treating addictive behaviors
WO2005021722A3 (en) METHODS AND COMPOSITIONS FOR INHIBITION OF NUCLEAR FACTOR κB
AU2003213459A1 (en) External medicine for wounds

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed